BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0124.p (471 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8ISF8.1 D8ISF8_HERSS GDP-mannose pyrophosphorylase protein EC=2... 962 0.0 A4G335.2 A4G335_HERAR Mannose-1-phosphate guanylyltransferase [G... 668 0.0 C6WXN8.1 C6WXN8_METML Mannose-1-phosphate guanylyltransferase/ma... 635 e-180 A6SVN9.1 A6SVN9_JANMA Mannose-6-phosphate isomerase / mannose-1-... 632 e-179 Q83VQ4.1 Q83VQ4_9PROT GDP-mannose pyrophosphorylase EpsQ 625 e-177 Q3SJG9.1 Q3SJG9_THIDA Mannose-1-phosphate guanylyltransferase/ma... 623 e-176 C6X6S1.1 C6X6S1_METSD Mannose-1-phosphate guanylyltransferase/ma... 615 e-174 F0BD02.1 F0BD02_9XANT Mannose-1-phosphate guanylyltransferase (G... 580 e-163 Q3BP78.1 Q3BP78_XANC5 Phosphomannose isomerase / GDPmannose dehy... 575 e-162 F0BWQ7.1 F0BWQ7_9XANT Mannose-1-phosphate guanylyltransferase (G... 574 e-161 >D8ISF8.1 D8ISF8_HERSS GDP-mannose pyrophosphorylase protein EC=2.7.7.22 Length = 471 Score = 962 bits (2488), Expect = 0.0, Method: Compositional matrix adjust. Identities = 471/471 (100%), Positives = 471/471 (100%) Query: 1 MKIYPVILSGGAGTRLWPLSRAAYPKQLLPLVSEQTMLQETVARVCAWPEALAPLVVCGN 60 MKIYPVILSGGAGTRLWPLSRAAYPKQLLPLVSEQTMLQETVARVCAWPEALAPLVVCGN Sbjct: 1 MKIYPVILSGGAGTRLWPLSRAAYPKQLLPLVSEQTMLQETVARVCAWPEALAPLVVCGN 60 Query: 61 EHRFMIAEQLREMDVRPHAIVLEPQGKNTAPAVAAAALQLMRQDPDAVMLVLPADHVITN 120 EHRFMIAEQLREMDVRPHAIVLEPQGKNTAPAVAAAALQLMRQDPDAVMLVLPADHVITN Sbjct: 61 EHRFMIAEQLREMDVRPHAIVLEPQGKNTAPAVAAAALQLMRQDPDAVMLVLPADHVITN 120 Query: 121 REAFHEAVRAAMRSVEQGALVTFGITPSKPETGYGYILRGAAHGDTGNFAVERFVEKPDL 180 REAFHEAVRAAMRSVEQGALVTFGITPSKPETGYGYILRGAAHGDTGNFAVERFVEKPDL Sbjct: 121 REAFHEAVRAAMRSVEQGALVTFGITPSKPETGYGYILRGAAHGDTGNFAVERFVEKPDL 180 Query: 181 ERAQGFVADGRYYWNSGMFLLRARDYLEELELHRPLIAAAVKDAVAKAYTDLDFCRLGEA 240 ERAQGFVADGRYYWNSGMFLLRARDYLEELELHRPLIAAAVKDAVAKAYTDLDFCRLGEA Sbjct: 181 ERAQGFVADGRYYWNSGMFLLRARDYLEELELHRPLIAAAVKDAVAKAYTDLDFCRLGEA 240 Query: 241 AFGASPAESIDYAVMENTRRAVVVPADIGWSDVGSWSALQEVMPADAQGNVTRGDVYLDG 300 AFGASPAESIDYAVMENTRRAVVVPADIGWSDVGSWSALQEVMPADAQGNVTRGDVYLDG Sbjct: 241 AFGASPAESIDYAVMENTRRAVVVPADIGWSDVGSWSALQEVMPADAQGNVTRGDVYLDG 300 Query: 301 VSNSLVRAESRMVAVLGLQDLIVVETDDAVLVAHKDKAQDVKGVVDQLKDKKRSEHIHHK 360 VSNSLVRAESRMVAVLGLQDLIVVETDDAVLVAHKDKAQDVKGVVDQLKDKKRSEHIHHK Sbjct: 301 VSNSLVRAESRMVAVLGLQDLIVVETDDAVLVAHKDKAQDVKGVVDQLKDKKRSEHIHHK 360 Query: 361 RVYRPWGSYESVDAGDRFQVKRIIVKPGEKLSLQMHYHRAEHWVVVSGSALVTRGEEVTL 420 RVYRPWGSYESVDAGDRFQVKRIIVKPGEKLSLQMHYHRAEHWVVVSGSALVTRGEEVTL Sbjct: 361 RVYRPWGSYESVDAGDRFQVKRIIVKPGEKLSLQMHYHRAEHWVVVSGSALVTRGEEVTL 420 Query: 421 LSENESIYLPIGVTHRLENPGKLPLHLIEVQSGSYLGEDDIVRFDDVYKRA 471 LSENESIYLPIGVTHRLENPGKLPLHLIEVQSGSYLGEDDIVRFDDVYKRA Sbjct: 421 LSENESIYLPIGVTHRLENPGKLPLHLIEVQSGSYLGEDDIVRFDDVYKRA 471 >A4G335.2 A4G335_HERAR Mannose-1-phosphate guanylyltransferase [GDP] (GDP-mannose pyrophosphorylase) (GMP) EC=2.7.7.22 Length = 472 Score = 668 bits (1724), Expect = 0.0, Method: Compositional matrix adjust. Identities = 329/472 (69%), Positives = 392/472 (83%), Gaps = 1/472 (0%) Query: 1 MKIYPVILSGGAGTRLWPLSRAAYPKQLLPLVSEQTMLQETVARVCAWPEALAPLVVCGN 60 MKIYPVILSGG+G+RLWPLSRAA PKQLLPLVSE+TMLQETV RV WPE PL+VCG+ Sbjct: 1 MKIYPVILSGGSGSRLWPLSRAALPKQLLPLVSERTMLQETVLRVAGWPEIAPPLIVCGD 60 Query: 61 EHRFMIAEQLREMDVRPHAIVLEPQGKNTAPAVAAAALQLMRQDPDAVMLVLPADHVITN 120 +HRF++AEQLR++D +P AI+LE +G+NTAPAVAAAA L+ +DPDA+MLVLPADH+I + Sbjct: 61 DHRFLVAEQLRQIDSKPTAILLEAEGRNTAPAVAAAANYLLARDPDALMLVLPADHLIID 120 Query: 121 REAFHEAVRAAMRSVEQGALVTFGITPSKPETGYGYILRGAAHGDTGN-FAVERFVEKPD 179 +AFHEAV A +V + AL TFGI PS ETGYGYI RGAA + FAVERFVEKPD Sbjct: 121 ADAFHEAVLVAAHAVGKHALATFGILPSAAETGYGYIRRGAAIDRSETCFAVERFVEKPD 180 Query: 180 LERAQGFVADGRYYWNSGMFLLRARDYLEELELHRPLIAAAVKDAVAKAYTDLDFCRLGE 239 L AQ F+AD RY WNSGMFL RA YL ELE +P +AA K AV AY+DL FCRL E Sbjct: 181 LATAQAFLADERYSWNSGMFLFRADTYLAELERLQPEMAACSKAAVQDAYSDLSFCRLHE 240 Query: 240 AAFGASPAESIDYAVMENTRRAVVVPADIGWSDVGSWSALQEVMPADAQGNVTRGDVYLD 299 AA+ A P++SID+AVME+T++A+V+PADIGWSD+GSWSAL E+ +AQGNV +GDVY D Sbjct: 241 AAYAACPSQSIDFAVMEHTQQAIVIPADIGWSDIGSWSALSEMQDGNAQGNVLQGDVYAD 300 Query: 300 GVSNSLVRAESRMVAVLGLQDLIVVETDDAVLVAHKDKAQDVKGVVDQLKDKKRSEHIHH 359 V NSL+RAESR V+V+GL +++VVET DAVL+ +KD+ Q VK VVD LK K R EH++H Sbjct: 301 NVQNSLIRAESRFVSVIGLDNVVVVETRDAVLIVNKDQVQRVKNVVDFLKQKNRCEHLNH 360 Query: 360 KRVYRPWGSYESVDAGDRFQVKRIIVKPGEKLSLQMHYHRAEHWVVVSGSALVTRGEEVT 419 RVYRPWGSYE +DAG+RFQVKRI V PGEKLSLQMH+HRAEHWVVV+G+A +T GE V Sbjct: 361 TRVYRPWGSYEPIDAGERFQVKRITVDPGEKLSLQMHHHRAEHWVVVTGTARITCGETVR 420 Query: 420 LLSENESIYLPIGVTHRLENPGKLPLHLIEVQSGSYLGEDDIVRFDDVYKRA 471 LL+ENESIY+PIG+THRLENPGK+PLHLIEVQSG+YLGEDDIVRFDDVY+RA Sbjct: 421 LLTENESIYIPIGMTHRLENPGKMPLHLIEVQSGAYLGEDDIVRFDDVYQRA 472 >C6WXN8.1 C6WXN8_METML Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase EC=2.7.7.13 Length = 473 Score = 635 bits (1637), Expect = e-180, Method: Compositional matrix adjust. Identities = 313/475 (65%), Positives = 373/475 (78%), Gaps = 9/475 (1%) Query: 2 KIYPVILSGGAGTRLWPLSRAAYPKQLLPLVSEQTMLQETVARVCAWPEALAPLVVCGNE 61 KI PVILSGGAGTRLWPLSRAA PKQLLPL+SE +MLQET+ R+ WPE LAP+VVCGN+ Sbjct: 3 KIIPVILSGGAGTRLWPLSRAALPKQLLPLLSEHSMLQETILRLADWPEVLAPMVVCGND 62 Query: 62 HRFMIAEQLREMDVRPHAIVLEPQGKNTAPAVAAAALQLMRQDPDAVMLVLPADHVITNR 121 HRF++AEQLRE+ V PH+I+LEP G+NTAPA+A AA + DA+MLVLPADHVI + Sbjct: 63 HRFLVAEQLREIQVLPHSIMLEPVGRNTAPAIAVAAYGVEEGAEDALMLVLPADHVIRDV 122 Query: 122 EAFHEAVRAAMRSVEQGALVTFGITPSKPETGYGYILRGAAHGDT-----GNFAVERFVE 176 +AFH AV+ A ++ QG LVTFGI PS PETGYGYI +G DT G+F V++FVE Sbjct: 123 KAFHLAVQVAAKAAAQGRLVTFGIQPSSPETGYGYIKKG----DTDRVAEGSFTVQKFVE 178 Query: 177 KPDLERAQGFVADGRYYWNSGMFLLRARDYLEELELHRPLIAAAVKDAVAKAYTDLDFCR 236 KP+ + A+G+VA G Y+WNSGMFL + YL EL RP IA K + +Y DLDFCR Sbjct: 179 KPNRDVAEGYVASGDYFWNSGMFLFKPSAYLAELARLRPDIADITKQSFEGSYRDLDFCR 238 Query: 237 LGEAAFGASPAESIDYAVMENTRRAVVVPADIGWSDVGSWSALQEVMPADAQGNVTRGDV 296 L E +F P++SIDYAVMENT A +VP D+GW+DVGSW+AL EV D GN RGDV Sbjct: 239 LEEKSFMQCPSDSIDYAVMENTHLAALVPVDMGWNDVGSWTALWEVQSQDEAGNALRGDV 298 Query: 297 YLDGVSNSLVRAESRMVAVLGLQDLIVVETDDAVLVAHKDKAQDVKGVVDQLKDKKRSEH 356 Y+D V SLVRAE R+VA +G++DL+++ET DAVLVAHKD+AQDVK +VD LK RSEH Sbjct: 299 YVDDVKRSLVRAEGRIVAAIGVEDLVIIETSDAVLVAHKDRAQDVKKIVDHLKRNGRSEH 358 Query: 357 IHHKRVYRPWGSYESVDAGDRFQVKRIIVKPGEKLSLQMHYHRAEHWVVVSGSALVTRGE 416 H RVYRPWGSYE VD G+RFQVKRIIV PG KLSLQMH+HRAEHWVVVSG+ALVTR Sbjct: 359 EVHARVYRPWGSYEGVDIGERFQVKRIIVNPGSKLSLQMHHHRAEHWVVVSGTALVTRDG 418 Query: 417 EVTLLSENESIYLPIGVTHRLENPGKLPLHLIEVQSGSYLGEDDIVRFDDVYKRA 471 + +LSEN+S Y+PIGVTHRLENPGKLPLHLIE+QSGSYLGEDDIVR++D Y R+ Sbjct: 419 KTEMLSENQSTYIPIGVTHRLENPGKLPLHLIEIQSGSYLGEDDIVRYEDTYGRS 473 >A6SVN9.1 A6SVN9_JANMA Mannose-6-phosphate isomerase / mannose-1-phosphate guanylyltransferase EC=2.7.7.22 Length = 470 Score = 632 bits (1629), Expect = e-179, Method: Compositional matrix adjust. Identities = 315/471 (66%), Positives = 376/471 (79%), Gaps = 3/471 (0%) Query: 3 IYPVILSGGAGTRLWPLSRAAYPKQLLPLVSEQTMLQETVARVCAWPEALAPLVVCGNEH 62 +YPVILSGG+G+RLWPLSRAA PKQLLPLVSE+TMLQ+TV R+ W PLVVCG++H Sbjct: 1 MYPVILSGGSGSRLWPLSRAALPKQLLPLVSERTMLQDTVLRISGWKGMAPPLVVCGDDH 60 Query: 63 RFMIAEQLREMDVRPHAIVLEPQGKNTAPAVAAAALQLMRQDPDAVMLVLPADHVITNRE 122 RF++AEQLR++ + P AI+LE QG+NTAPAVAAAA L DPDAVMLVLPADHVI + + Sbjct: 61 RFLVAEQLRQIGITPTAILLEAQGRNTAPAVAAAANYLAAIDPDAVMLVLPADHVIVDDD 120 Query: 123 AFHEAVRAAMRSVEQGALVTFGITPSKPETGYGYILRGAAHGDTGN--FAVERFVEKPDL 180 AFH AV A ++ AL TFGI P+ ETGYGYI RGAA DT N FAVERFVEKPD Sbjct: 121 AFHVAVMLAADAIGSTALATFGIVPTAAETGYGYIRRGAAL-DTSNTCFAVERFVEKPDR 179 Query: 181 ERAQGFVADGRYYWNSGMFLLRARDYLEELELHRPLIAAAVKDAVAKAYTDLDFCRLGEA 240 A+ F+AD Y WNSGMF+ RA YL EL+ +P +A AV AY+DL FCRL E Sbjct: 180 ATAEKFIADKNYSWNSGMFMFRASAYLAELQRLQPEMAQCCALAVHDAYSDLSFCRLDET 239 Query: 241 AFGASPAESIDYAVMENTRRAVVVPADIGWSDVGSWSALQEVMPADAQGNVTRGDVYLDG 300 A+ A PAESID+AVME+T A+V+P DIGWSDVGSWSAL E+ P D GN+ GDVY DG Sbjct: 240 AYAACPAESIDFAVMEHTPHALVIPVDIGWSDVGSWSALAEIKPGDKDGNILHGDVYADG 299 Query: 301 VSNSLVRAESRMVAVLGLQDLIVVETDDAVLVAHKDKAQDVKGVVDQLKDKKRSEHIHHK 360 V+++L+R+ESR VA +G+ +LIVVET DAVL+ KD+ Q VK VV+ LK ++RSEH++H Sbjct: 300 VTDTLIRSESRFVAAIGVDNLIVVETRDAVLIVAKDQVQRVKQVVEHLKLEQRSEHLNHT 359 Query: 361 RVYRPWGSYESVDAGDRFQVKRIIVKPGEKLSLQMHYHRAEHWVVVSGSALVTRGEEVTL 420 RVYRPWG YE +DAG+RFQVKRI V PGEKLSLQMH+HRAEHWVVV+G+A +T GE V L Sbjct: 360 RVYRPWGCYEGIDAGERFQVKRITVDPGEKLSLQMHHHRAEHWVVVTGTARITCGENVRL 419 Query: 421 LSENESIYLPIGVTHRLENPGKLPLHLIEVQSGSYLGEDDIVRFDDVYKRA 471 L+ENESIY+PIG+THRLENPGK+PLHLIEVQSG+YLGEDDIVRFDDVY+RA Sbjct: 420 LTENESIYIPIGMTHRLENPGKMPLHLIEVQSGAYLGEDDIVRFDDVYQRA 470 >Q83VQ4.1 Q83VQ4_9PROT GDP-mannose pyrophosphorylase EpsQ Length = 473 Score = 625 bits (1613), Expect = e-177, Method: Compositional matrix adjust. Identities = 305/473 (64%), Positives = 373/473 (78%), Gaps = 2/473 (0%) Query: 1 MKIYPVILSGGAGTRLWPLSRAAYPKQLLPLVSEQTMLQETVARVCAWPEALAPLVVCGN 60 MKI PVILSGG+GTRLWPLSR A PKQLLPL S +MLQET+ R+ +P+VVCGN Sbjct: 1 MKIVPVILSGGSGTRLWPLSRQALPKQLLPLTSGHSMLQETLLRLSGVESIESPIVVCGN 60 Query: 61 EHRFMIAEQLREMDVRPHAIVLEPQGKNTAPAVAAAALQLMRQDP-DAVMLVLPADHVIT 119 +HRF++AEQL E+ +P AIVLEP G+NTAPA+A AA +L++++ D +MLVLPADHVI Sbjct: 61 DHRFLVAEQLLEIGSKPKAIVLEPVGRNTAPAIAVAASRLLQENAEDVLMLVLPADHVIQ 120 Query: 120 NREAFHEAVRAAMRSVEQGALVTFGITPSKPETGYGYILRGAAHGDT-GNFAVERFVEKP 178 NR AF A+ A ++ + G LVTFGI P+ PETGYGYI GAA G+F + RFVEKP Sbjct: 121 NRAAFSAAIAVAAQAAKSGRLVTFGIKPTVPETGYGYINGGAALASCPGSFELSRFVEKP 180 Query: 179 DLERAQGFVADGRYYWNSGMFLLRARDYLEELELHRPLIAAAVKDAVAKAYTDLDFCRLG 238 +LE A+ ++A G YYWNSGMFL + Y+EEL P IA+ +A+ ++YTDLDF RL Sbjct: 181 NLETAKQYLASGDYYWNSGMFLFSPKQYMEELTQFAPEIASKASEALEQSYTDLDFVRLH 240 Query: 239 EAAFGASPAESIDYAVMENTRRAVVVPADIGWSDVGSWSALQEVMPADAQGNVTRGDVYL 298 EA+F P++S+DYAVME+TR A VVP DIGWSDVGSW+AL +V+ D GNVT GDVYL Sbjct: 241 EASFKECPSQSVDYAVMEHTRNAAVVPVDIGWSDVGSWTALADVLDKDDAGNVTVGDVYL 300 Query: 299 DGVSNSLVRAESRMVAVLGLQDLIVVETDDAVLVAHKDKAQDVKGVVDQLKDKKRSEHIH 358 +GV NS+VR+E RMVA LG+++LI+VET DAVLVAHKD AQDVK +VD LK++ R EH + Sbjct: 301 NGVKNSMVRSEGRMVAALGVENLIIVETSDAVLVAHKDAAQDVKKIVDYLKEQGRKEHEY 360 Query: 359 HKRVYRPWGSYESVDAGDRFQVKRIIVKPGEKLSLQMHYHRAEHWVVVSGSALVTRGEEV 418 H RVYRPWG YE +DA +RFQVKRI+VKPGEKLSLQMH+HRAEHWVVVSG+A+VT+ E Sbjct: 361 HSRVYRPWGWYEGIDAAERFQVKRIMVKPGEKLSLQMHHHRAEHWVVVSGTAIVTKNGEA 420 Query: 419 TLLSENESIYLPIGVTHRLENPGKLPLHLIEVQSGSYLGEDDIVRFDDVYKRA 471 +L EN+S Y+PIG THRLENPGKLPLHLIEVQSG YLGEDDIVRF+D Y R+ Sbjct: 421 EMLCENQSTYIPIGATHRLENPGKLPLHLIEVQSGGYLGEDDIVRFEDTYGRS 473 >Q3SJG9.1 Q3SJG9_THIDA Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase EC=2.7.7.22 Length = 472 Score = 623 bits (1607), Expect = e-176, Method: Compositional matrix adjust. Identities = 310/471 (65%), Positives = 375/471 (79%), Gaps = 1/471 (0%) Query: 1 MKIYPVILSGGAGTRLWPLSRAAYPKQLLPLVSEQTMLQETVARVCAWPEALAPLVVCGN 60 M I+PVILSGG+GTRLWPLSRAA PKQLLPL SE+++LQ+TV R+ +P+ APL+VC Sbjct: 1 MTIHPVILSGGSGTRLWPLSRAALPKQLLPLASERSLLQDTVLRLADFPDMAAPLMVCNV 60 Query: 61 EHRFMIAEQLREMDVRPHAIVLEPQGKNTAPAVAAAALQLMRQDPDAVMLVLPADHVITN 120 EHRFMIAEQ+R++ V P AIVLEP G+NTAPA+A AAL+L R+D DA+MLVLPADH+I + Sbjct: 61 EHRFMIAEQMRQIGVHPSAIVLEPVGRNTAPAIAVAALRLSREDADALMLVLPADHLIGD 120 Query: 121 REAFHEAVRAAMRSVEQGALVTFGITPSKPETGYGYILRG-AAHGDTGNFAVERFVEKPD 179 AFH A+ A + + G L TFGI + PETGYGYI +G A G AV FVEKPD Sbjct: 121 IAAFHAAITRAADAAKHGYLATFGIVAATPETGYGYIRKGDALAEAAGAHAVAGFVEKPD 180 Query: 180 LERAQGFVADGRYYWNSGMFLLRARDYLEELELHRPLIAAAVKDAVAKAYTDLDFCRLGE 239 L AQ +VA G Y+WNSGMFL RA D+L+ELE RP I +A + A+ A DLDF RL Sbjct: 181 LATAQQYVASGDYFWNSGMFLFRASDFLKELETLRPDILSASRAALDAAKPDLDFVRLDP 240 Query: 240 AAFGASPAESIDYAVMENTRRAVVVPADIGWSDVGSWSALQEVMPADAQGNVTRGDVYLD 299 AF A P+ES+DYAVME+TRRA VVPADIGW+D+G+WSAL EV DA GN RGDV L+ Sbjct: 241 VAFEACPSESVDYAVMEHTRRAAVVPADIGWNDIGAWSALWEVAEKDAAGNAVRGDVMLE 300 Query: 300 GVSNSLVRAESRMVAVLGLQDLIVVETDDAVLVAHKDKAQDVKGVVDQLKDKKRSEHIHH 359 +N+ VRAE+RMVA+LG+ DL+VVET D VLVA++D+ QDVK +VD+LK KR EH+ H Sbjct: 301 NAANNFVRAETRMVAMLGVSDLVVVETADVVLVANRDQVQDVKKLVDRLKAAKRCEHLVH 360 Query: 360 KRVYRPWGSYESVDAGDRFQVKRIIVKPGEKLSLQMHYHRAEHWVVVSGSALVTRGEEVT 419 K+VYRPWG YE +D GDRFQVKRI+VKPGEKLSLQMH+HRAEHWVVVSG+A VT G+EV Sbjct: 361 KQVYRPWGWYEGIDGGDRFQVKRIMVKPGEKLSLQMHHHRAEHWVVVSGTASVTCGDEVM 420 Query: 420 LLSENESIYLPIGVTHRLENPGKLPLHLIEVQSGSYLGEDDIVRFDDVYKR 470 LL+EN+S Y+P+G THRLENPGK+ LH+IEVQSG+YLGEDDIVRF+DVYKR Sbjct: 421 LLAENQSTYIPLGTTHRLENPGKVDLHMIEVQSGTYLGEDDIVRFEDVYKR 471 >C6X6S1.1 C6X6S1_METSD Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase EC=2.7.7.13 Length = 472 Score = 615 bits (1586), Expect = e-174, Method: Compositional matrix adjust. Identities = 301/470 (64%), Positives = 368/470 (78%), Gaps = 2/470 (0%) Query: 3 IYPVILSGGAGTRLWPLSRAAYPKQLLPLVSEQTMLQETVARVCAWPEALAPLVVCGNEH 62 I PV+LSGG+GTRLWPLSR A PKQLLPL S +MLQET+ R+ +P+VVCGN+H Sbjct: 2 IVPVVLSGGSGTRLWPLSRQALPKQLLPLTSGYSMLQETLLRLNGVESIESPIVVCGNDH 61 Query: 63 RFMIAEQLREMDVRPHAIVLEPQGKNTAPAVAAAALQLMRQDP-DAVMLVLPADHVITNR 121 RF++AEQL E+ +P AIVLEP G+NTAPA+A AA +L++ + D +MLVLPADHVI N+ Sbjct: 62 RFLVAEQLLEIGSKPKAIVLEPVGRNTAPAIAVAASRLLQDNAEDFLMLVLPADHVIQNK 121 Query: 122 EAFHEAVRAAMRSVEQGALVTFGITPSKPETGYGYILRGAAHGDT-GNFAVERFVEKPDL 180 AF A+ A ++ E G LVTFGI P+ PETGYGYI GAA G+F + RFVEKP+L Sbjct: 122 AAFSAAIAVAAQAAESGRLVTFGIKPTLPETGYGYINGGAALASCPGSFELSRFVEKPNL 181 Query: 181 ERAQGFVADGRYYWNSGMFLLRARDYLEELELHRPLIAAAVKDAVAKAYTDLDFCRLGEA 240 E A+ ++A G YYWNSGMFL + Y+EEL P IA+ +A+ ++YTDLDF RL EA Sbjct: 182 ETAKQYLASGDYYWNSGMFLFSPKQYMEELTKFAPEIASKASEALEQSYTDLDFVRLHEA 241 Query: 241 AFGASPAESIDYAVMENTRRAVVVPADIGWSDVGSWSALQEVMPADAQGNVTRGDVYLDG 300 +F P++S+DYAVME+T A VVP DIGWSDVGSW+AL +V+ D GNVT GDVYL+G Sbjct: 242 SFKECPSQSVDYAVMEHTCNAAVVPVDIGWSDVGSWTALADVLDKDDAGNVTVGDVYLNG 301 Query: 301 VSNSLVRAESRMVAVLGLQDLIVVETDDAVLVAHKDKAQDVKGVVDQLKDKKRSEHIHHK 360 V NS+VR+E RMVA LG+++LI+VET DAVLVAHKD AQDVK +VD LK++ R EH +H Sbjct: 302 VKNSMVRSEGRMVAALGVENLIIVETSDAVLVAHKDAAQDVKKIVDYLKEQGRKEHEYHS 361 Query: 361 RVYRPWGSYESVDAGDRFQVKRIIVKPGEKLSLQMHYHRAEHWVVVSGSALVTRGEEVTL 420 RVYRPWG YE +DA +RFQVKRI+VKPGEKLSLQMH+HRAEHWVVVSG+A+VT+ E + Sbjct: 362 RVYRPWGWYEGIDAAERFQVKRIMVKPGEKLSLQMHHHRAEHWVVVSGTAIVTKNGEAEM 421 Query: 421 LSENESIYLPIGVTHRLENPGKLPLHLIEVQSGSYLGEDDIVRFDDVYKR 470 L EN+S Y+PIG THRLENPGKLPLHLIEVQSG YLGEDDIVRF+D Y R Sbjct: 422 LCENQSTYIPIGTTHRLENPGKLPLHLIEVQSGGYLGEDDIVRFEDTYGR 471 >F0BD02.1 F0BD02_9XANT Mannose-1-phosphate guanylyltransferase (GDP) EC=2.7.7.22 EC=5.3.1.8 Length = 467 Score = 580 bits (1494), Expect = e-163, Method: Compositional matrix adjust. Identities = 289/469 (61%), Positives = 348/469 (74%), Gaps = 5/469 (1%) Query: 3 IYPVILSGGAGTRLWPLSRAAYPKQLLPLVSEQTMLQETVARVCAWPEALAPLVVCGNEH 62 + P+ILSGG+GTRLWPLSR +YPKQ LPLV +++MLQ T R A AP+VV EH Sbjct: 4 VLPIILSGGSGTRLWPLSRESYPKQFLPLVGDKSMLQATWLR-AAPVAGHAPIVVANEEH 62 Query: 63 RFMIAEQLREMDVRPHAIVLEPQGKNTAPAVAAAALQLMRQDPDAVMLVLPADHVITNRE 122 RFM AEQL+++ V+P AI+LEP+G+NTAPA+A AAL+ MR D ++LVLP+DHVI + Sbjct: 63 RFMAAEQLQQLGVKPSAILLEPKGRNTAPAIAVAALEAMRDGADPLLLVLPSDHVIGDEA 122 Query: 123 AFHEAVRAAMRSVEQGALVTFGITPSKPETGYGYILRGAAHGDTGNFAVERFVEKPDLER 182 AF V+ A + QG LVTFGI P+ PETGYGYI G+ TG AVERFVEKPDL Sbjct: 123 AFQAGVKVAAEAAAQGKLVTFGIKPTAPETGYGYIKAGSG---TGATAVERFVEKPDLAT 179 Query: 183 AQGFVADGRYYWNSGMFLLRARDYLEELELHRPLIAAAVKDAVAKAYTDLDFCRLGEAAF 242 AQG++A G YYWNSGMFL RA YLEEL P IA A + A D DF RL + AF Sbjct: 180 AQGYLASGEYYWNSGMFLFRASRYLEELRKFHPAIADACQKAWQNGKRDADFTRLDKDAF 239 Query: 243 GASPAESIDYAVMENTRRAVVVPADIGWSDVGSWSALQEVMPADAQGNVTRGDVYLDGVS 302 ASP++SIDYAVME T AVVVP D GW+DVGSWS+L +V DAQGN GDV Sbjct: 240 AASPSDSIDYAVMEKTADAVVVPLDAGWNDVGSWSSLLDVSEQDAQGNAHHGDVIQIDCQ 299 Query: 303 NSLVRAESRMVAVLGLQDLIVVETDDAVLVAHKDKAQDVKGVVDQLKDKKRSEHIHHKRV 362 N+ SR++A++GL+D++VVET DAVLV H+D+ Q+VK VV Q+K RSE H++V Sbjct: 300 NTYAYG-SRLIAMVGLEDVVVVETPDAVLVGHRDRIQEVKDVVSQIKTAGRSEATWHRKV 358 Query: 363 YRPWGSYESVDAGDRFQVKRIIVKPGEKLSLQMHYHRAEHWVVVSGSALVTRGEEVTLLS 422 YRPWG+Y+S+D G R QVKRI VKPG LSLQMH+HRAEHW+VVSG+A VTRGEEV LL+ Sbjct: 359 YRPWGAYDSIDMGQRHQVKRITVKPGAVLSLQMHHHRAEHWIVVSGTAEVTRGEEVLLLT 418 Query: 423 ENESIYLPIGVTHRLENPGKLPLHLIEVQSGSYLGEDDIVRFDDVYKRA 471 EN+S Y+P+GVTHRL NPGKLPL LIEVQSGSYLGEDDIVRF+D Y RA Sbjct: 419 ENQSTYIPLGVTHRLRNPGKLPLELIEVQSGSYLGEDDIVRFEDTYGRA 467 >Q3BP78.1 Q3BP78_XANC5 Phosphomannose isomerase / GDPmannose dehydrogenase Length = 467 Score = 575 bits (1482), Expect = e-162, Method: Compositional matrix adjust. Identities = 290/469 (61%), Positives = 348/469 (74%), Gaps = 5/469 (1%) Query: 3 IYPVILSGGAGTRLWPLSRAAYPKQLLPLVSEQTMLQETVARVCAWPEALAPLVVCGNEH 62 + P+ILSGG+GTRLWPLSR +YPKQ LPLV +++MLQ T R A AP+VV EH Sbjct: 4 VLPIILSGGSGTRLWPLSRESYPKQFLPLVGDKSMLQSTWLR-AAPVAGHAPIVVANEEH 62 Query: 63 RFMIAEQLREMDVRPHAIVLEPQGKNTAPAVAAAALQLMRQDPDAVMLVLPADHVITNRE 122 RFM AEQL+++ V+P AI+LEP+G+NTAPA+A AAL+ R D ++LVLP+DHVI N Sbjct: 63 RFMAAEQLQQLGVKPSAILLEPKGRNTAPAIAVAALEATRDGADPLLLVLPSDHVIQNEA 122 Query: 123 AFHEAVRAAMRSVEQGALVTFGITPSKPETGYGYILRGAAHGDTGNFAVERFVEKPDLER 182 AF AV A + EQG LVTFGI P+ PETGYGYI GA TG AVERFVEKPDL Sbjct: 123 AFQAAVTLAATAAEQGKLVTFGIKPTAPETGYGYIKAGAG---TGASAVERFVEKPDLAT 179 Query: 183 AQGFVADGRYYWNSGMFLLRARDYLEELELHRPLIAAAVKDAVAKAYTDLDFCRLGEAAF 242 AQ ++A G YYWNSGMFL RA YLEEL P IA A + A D DF RL + AF Sbjct: 180 AQSYLASGEYYWNSGMFLFRASRYLEELRKFHPAIADACQKAWENGKRDADFTRLDKDAF 239 Query: 243 GASPAESIDYAVMENTRRAVVVPADIGWSDVGSWSALQEVMPADAQGNVTRGDVYLDGVS 302 ASP++SIDYAVME T AVVVP D GW+DVGSWS+L++V DAQGN GDV Sbjct: 240 AASPSDSIDYAVMEKTADAVVVPLDAGWNDVGSWSSLRDVSKQDAQGNAHHGDVIQLDCQ 299 Query: 303 NSLVRAESRMVAVLGLQDLIVVETDDAVLVAHKDKAQDVKGVVDQLKDKKRSEHIHHKRV 362 N+ SR++A++GL+D++VVET DAVLV H+D+ Q+VK +V Q+K RSE H++V Sbjct: 300 NTYAYG-SRLIAMVGLEDVVVVETPDAVLVGHRDRIQEVKDIVSQIKTAGRSEATWHRKV 358 Query: 363 YRPWGSYESVDAGDRFQVKRIIVKPGEKLSLQMHYHRAEHWVVVSGSALVTRGEEVTLLS 422 YRPWG+Y+S+D G R QVKRI VKPG LSLQMH+HRAEHW+VVSG+A VTRGEEV LL+ Sbjct: 359 YRPWGAYDSIDMGQRHQVKRITVKPGAVLSLQMHHHRAEHWIVVSGTAEVTRGEEVLLLT 418 Query: 423 ENESIYLPIGVTHRLENPGKLPLHLIEVQSGSYLGEDDIVRFDDVYKRA 471 EN+S Y+P+GVTHRL NPGKLPL LIEVQSGSYLGEDDIVRF+D Y RA Sbjct: 419 ENQSTYIPLGVTHRLRNPGKLPLELIEVQSGSYLGEDDIVRFEDTYGRA 467 >F0BWQ7.1 F0BWQ7_9XANT Mannose-1-phosphate guanylyltransferase (GDP) EC=2.7.7.22 EC=5.3.1.8 Length = 467 Score = 574 bits (1480), Expect = e-161, Method: Compositional matrix adjust. Identities = 291/469 (62%), Positives = 347/469 (73%), Gaps = 5/469 (1%) Query: 3 IYPVILSGGAGTRLWPLSRAAYPKQLLPLVSEQTMLQETVARVCAWPEALAPLVVCGNEH 62 + P+ILSGG+GTRLWPLSR +YPKQ LPLV +++MLQ T R A AP+VV EH Sbjct: 4 VLPIILSGGSGTRLWPLSRESYPKQFLPLVGDKSMLQSTWLR-AAPVAGHAPIVVANEEH 62 Query: 63 RFMIAEQLREMDVRPHAIVLEPQGKNTAPAVAAAALQLMRQDPDAVMLVLPADHVITNRE 122 RFM AEQL+++ V+P AI+LEP+G+NTAPA+A AAL+ R D ++LVLP+DHVI N Sbjct: 63 RFMAAEQLQQLGVKPSAILLEPKGRNTAPAIAVAALEATRDGADPLLLVLPSDHVIQNEA 122 Query: 123 AFHEAVRAAMRSVEQGALVTFGITPSKPETGYGYILRGAAHGDTGNFAVERFVEKPDLER 182 AF AV A + EQG LVTFGI P+ PETGYGYI GA TG AVERFVEKPDL Sbjct: 123 AFQAAVTLAATAAEQGKLVTFGIKPTAPETGYGYIKAGAG---TGASAVERFVEKPDLAT 179 Query: 183 AQGFVADGRYYWNSGMFLLRARDYLEELELHRPLIAAAVKDAVAKAYTDLDFCRLGEAAF 242 AQ ++A G YYWNSGMFL RA YLEEL P IA A + A D DF RL + AF Sbjct: 180 AQSYLASGEYYWNSGMFLFRASRYLEELRKFHPAIADACQKAWENGKRDADFTRLDKDAF 239 Query: 243 GASPAESIDYAVMENTRRAVVVPADIGWSDVGSWSALQEVMPADAQGNVTRGDVYLDGVS 302 ASP++SIDYAVME T AVVVP D GW+DVGSWS+L +V DAQGN GDV Sbjct: 240 AASPSDSIDYAVMEKTADAVVVPLDAGWNDVGSWSSLLDVSSQDAQGNAHHGDVIQLDCQ 299 Query: 303 NSLVRAESRMVAVLGLQDLIVVETDDAVLVAHKDKAQDVKGVVDQLKDKKRSEHIHHKRV 362 N+ SR++A++GL+D++VVET DAVLV H+D+ Q+VK VV Q+K RSE H++V Sbjct: 300 NTYAYG-SRLIAMVGLEDVVVVETPDAVLVGHRDRIQEVKDVVSQIKTAGRSEATWHRKV 358 Query: 363 YRPWGSYESVDAGDRFQVKRIIVKPGEKLSLQMHYHRAEHWVVVSGSALVTRGEEVTLLS 422 YRPWG+Y+S+D G R QVKRI VKPG LSLQMH+HRAEHW+VVSG+A VTRGEEV LL+ Sbjct: 359 YRPWGAYDSIDMGQRHQVKRITVKPGAVLSLQMHHHRAEHWIVVSGTAEVTRGEEVLLLT 418 Query: 423 ENESIYLPIGVTHRLENPGKLPLHLIEVQSGSYLGEDDIVRFDDVYKRA 471 EN+S Y+P+GVTHRL NPGKLPL LIEVQSGSYLGEDDIVRF+D Y RA Sbjct: 419 ENQSTYIPLGVTHRLRNPGKLPLELIEVQSGSYLGEDDIVRFEDTYGRA 467