BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0074.p (556 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IR80.1 D8IR80_HERSS Two component sensor histidine kinase prot... 1125 0.0 Q07PA3.1 Q07PA3_RHOP5 Periplasmic sensor hybrid histidine kinase 350 3e-94 A4YWZ3.1 A4YWZ3_BRASO Putative sensor histidine kinase with a re... 345 2e-92 A5EHF7.1 A5EHF7_BRASB Putative sensor histidine kinase with a re... 320 3e-85 B1Y0E3.1 B1Y0E3_LEPCP Histidine kinase EC=2.7.13.3 282 1e-73 C5T5I5.1 C5T5I5_ACIDE PAS/PAC sensor signal transduction histidi... 270 4e-70 F0QBD7.1 F0QBD7_ACIAP Integral membrane sensor signal transducti... 264 3e-68 A1TRR9.1 A1TRR9_ACIAC Integral membrane sensor signal transducti... 252 1e-64 A4U3D7.1 A4U3D7_9PROT Signal transduction histidine kinase 239 1e-60 B3E5C2.1 B3E5C2_GEOLS Histidine kinase EC=2.7.13.3 235 2e-59 >D8IR80.1 D8IR80_HERSS Two component sensor histidine kinase protein EC=2.7.3.- Length = 556 Score = 1125 bits (2909), Expect = 0.0, Method: Compositional matrix adjust. Identities = 553/556 (99%), Positives = 554/556 (99%) Query: 1 MDDRKQQSLPLRFARIDLRVALSLFSLLLICGLWLGAFKELQNSRNNYLDDARRDAQSLS 60 MDDRKQQS PLRFARIDLRVALSLFSLLLICGLWLGAFKELQNSRNNYLDDARRDAQSLS Sbjct: 1 MDDRKQQSFPLRFARIDLRVALSLFSLLLICGLWLGAFKELQNSRNNYLDDARRDAQSLS 60 Query: 61 RLFLEHAYRTIEAADQAALYLRYRYAERGNALNLATEIDNGLVARNVYNLFSIVDAQGDV 120 RLFLEHAYRTIEAADQAALYLRYRYAERGNALNLATEIDNGLVARNVYNLFSIVDAQGDV Sbjct: 61 RLFLEHAYRTIEAADQAALYLRYRYAERGNALNLATEIDNGLVARNVYNLFSIVDAQGDV 120 Query: 121 VLSSKPFTPVNLADREHVQVHMQGGQDQLFISKPVLGRVSKKWSLQITRRINRPDGGFGG 180 VLSSKPFTPVNLADREHVQVHMQGGQDQLFISKPVLGRVSKKWSLQITRRINRPDGGFGG Sbjct: 121 VLSSKPFTPVNLADREHVQVHMQGGQDQLFISKPVLGRVSKKWSLQITRRINRPDGGFGG 180 Query: 181 VVVVSMDPQYFTRLYHQIDVGHHGVITLVGADGVARVRRTGDMDAMGEQVAGGKVYAAML 240 VVVVSMDPQYFTRLYHQIDVGHHGVITLVGADGVARVRRTGDMDAMGEQVAGGKVYAAML Sbjct: 181 VVVVSMDPQYFTRLYHQIDVGHHGVITLVGADGVARVRRTGDMDAMGEQVAGGKVYAAML 240 Query: 241 AQGSGTIEAVSKIDGRERLYAFQKLRDYPLFAAVGIDLEERLAPYYRERERTLMLAALLS 300 AQGSGTIEAVSKIDGRERLYAFQKLRDYPLFAAVGIDL+ERLAPYYRERERTLMLAALLS Sbjct: 241 AQGSGTIEAVSKIDGRERLYAFQKLRDYPLFAAVGIDLKERLAPYYRERERTLMLAALLS 300 Query: 301 VAVLVFNAVLLWLAGSLVRSRREALQANQAKSRFLSNMSHEFRTPLNGVLGYSDALREEL 360 VAVLVFNAVLLWLAGSLVRSRREALQANQAKSRFLSNMSHEFRTPLNGVLGYSDALREEL Sbjct: 301 VAVLVFNAVLLWLAGSLVRSRREALQANQAKSRFLSNMSHEFRTPLNGVLGYSDALREEL 360 Query: 361 GESPLAQYAVAIHDSGNRLLDLVNAILEVTELEDRRVAVHLDPANIRELVGQAIARHYPQ 420 GESPLAQYAVAIHDSGNRLLDLVNAILEVTELEDRRVAVHLDPANIRELVGQAIARHYPQ Sbjct: 361 GESPLAQYAVAIHDSGNRLLDLVNAILEVTELEDRRVAVHLDPANIRELVGQAIARHYPQ 420 Query: 421 AQAKGLPLECRIGEDVPQILVCDERKIQRVLDNLISNAVRYTDHGRVMVEVERSGAQQLT 480 AQAKGLPLECRIGEDVPQILVCDERKIQRVLDNLISNAVRYTDHGRVMVEVERSG QQLT Sbjct: 421 AQAKGLPLECRIGEDVPQILVCDERKIQRVLDNLISNAVRYTDHGRVMVEVERSGPQQLT 480 Query: 481 MRIKDTGIGIAASQQNDIFEKFTQADDSPRRSQEGAGLGLTIAQRLVMLMGGQLVLQSEQ 540 MRIKDTGIGIAASQQNDIFEKFTQADDSPRRSQEGAGLGLTIAQRLVMLMGGQLVLQSEQ Sbjct: 481 MRIKDTGIGIAASQQNDIFEKFTQADDSPRRSQEGAGLGLTIAQRLVMLMGGQLVLQSEQ 540 Query: 541 HQGSTFSFTLPLQEPK 556 HQGSTFSFTLPLQEPK Sbjct: 541 HQGSTFSFTLPLQEPK 556 >Q07PA3.1 Q07PA3_RHOP5 Periplasmic sensor hybrid histidine kinase Length = 729 Score = 350 bits (898), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 198/536 (36%), Positives = 308/536 (57%), Gaps = 11/536 (2%) Query: 29 LICGLWLGAFKELQNSRNNYLDDARRDAQSLSRLFLEHAYRTIEAADQAALYLRYRYAER 88 +I +W G + + A ++ +L+R F E R+I+AADQ LY+R YA Sbjct: 38 VIAIVWAGILSNISVDQTRTERAALQNNANLARAFEEQIVRSIKAADQTLLYVRDSYARA 97 Query: 89 GNALNLATEIDNGLVARNVYNLFSIVDAQGDVVLSSKPFTP----VNLADREHVQVHMQG 144 + +++ N + F +V D ++ S P ++L DREH +VH G Sbjct: 98 PASFDMSLWSKNSQFLTDFS--FQVVVIGKDGIMLSSNIDPTMKGLDLRDREHFRVHADG 155 Query: 145 GQDQLFISKPVLGRVSKKWSLQITRRINRPDGGFGGVVVVSMDPQYFTRLYHQIDVGHHG 204 +D LFISKP+ GRVSKKWS+Q+TRRI PDG FGGVVVVS+DP Y +R Y +++G +G Sbjct: 156 DKDFLFISKPIFGRVSKKWSVQLTRRIVMPDGSFGGVVVVSLDPNYLSRFYDSVEIGKNG 215 Query: 205 VITLVGADGVARVRRTGDMDAMGEQVAGGKVYAAMLAQGSGTIEAVSKIDGRERLYAFQK 264 +T+VG DG+ R R A+G +A G++ + + +G+ A S +DG R+++++K Sbjct: 216 SVTVVGFDGIIRARGASGPAAVGASLATGRLMSEFAQRPAGSFTAASAVDGVVRIFSYRK 275 Query: 265 LRDYPLFAAVGIDLEERLAPYYRERERTLMLAALLSVAVLVFNAVLLWLAGSLVRSRREA 324 + DYPL +VG +E APY +R++ +M+AALL++ ++V +A+++ L +SR A Sbjct: 276 VGDYPLVVSVGQASDEVFAPYRSDRDKDIMVAALLTLVIIVVSALIIRYQTGLAKSRDAA 335 Query: 325 LQANQAKSRFLSNMSHEFRTPLNGVLGYSDALREELGESPLAQYAVAIHDSGNRLLDLVN 384 +A+S FL+ MSHE RTP+NGV+G +D L + A + +S + LL L+N Sbjct: 336 EMGTRARSEFLAMMSHEIRTPMNGVIGLADLLVAADLPGEQNKIAATLRESADYLLQLLN 395 Query: 385 AILEVTELEDRRVAVHLDPANIRELVGQAIARHYPQAQAKGLPLECRIGEDVPQILVCDE 444 +L+ ++L+ R+ + + V I P+AQ KGL L RIG +VP + D Sbjct: 396 DVLDFSKLDANRLEIERIDFGLHRSVHATIDLLAPRAQEKGLSLTARIGPNVPDSITGDP 455 Query: 445 RKIQRVLDNLISNAVRYTDHGR----VMVEVERSGAQQLTMRIKDTGIGIAASQQNDIFE 500 +I++VL NL+ NA+++T G V E A +L ++ DTG+GI A +F Sbjct: 456 ARIRQVLFNLVGNAIKFTQAGSVEVVVEAEAAVGNAVRLVFKVIDTGVGIPAESLGLLFR 515 Query: 501 KFTQADDSPRRSQEGAGLGLTIAQRLVMLMGGQLVLQSEQHQGSTFSFTLPLQEPK 556 +F+Q D S R G GLGL I +RLV MGG++ +QS +GS F F++ L EP+ Sbjct: 516 EFSQGDSSISRRFGGTGLGLAICKRLVACMGGEISVQSRVGKGSVFRFSV-LVEPQ 570 >A4YWZ3.1 A4YWZ3_BRASO Putative sensor histidine kinase with a response regulator receiver domain Length = 731 Score = 345 bits (884), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 205/565 (36%), Positives = 312/565 (55%), Gaps = 21/565 (3%) Query: 7 QSLPLRFARIDLRV----------ALSLFSLLLICGLWLGAFKELQNSRNNYLDDARRDA 56 +S+P F R+D V ++ L I +W G F + + A ++ Sbjct: 7 KSMPF-FGRLDRAVDTMVRLIGHFGSAVIGLSAIALVWAGIFYTITEEHSRTEQSALKNG 65 Query: 57 QSLSRLFLEHAYRTIEAADQAALYLRYRYAERGNALNLATEIDNGLVARNVYNLFSIVDA 116 +L+R F E R+I AADQ LY+R YA+ +++ N + F +V Sbjct: 66 ANLARAFEEQIIRSIRAADQTLLYVRDSYAKDPQNFDMSLWSKNSQFLSDFS--FQVVVI 123 Query: 117 QGDVVLSSKPFTP----VNLADREHVQVHMQGGQDQLFISKPVLGRVSKKWSLQITRRIN 172 D ++ S P V+L DREH +VH G D LFISKP+ GRVS KWS+Q+TRRI Sbjct: 124 GKDGIMLSSNIDPKMRGVDLRDREHFRVHADGKDDFLFISKPIFGRVSNKWSIQLTRRII 183 Query: 173 RPDGGFGGVVVVSMDPQYFTRLYHQIDVGHHGVITLVGADGVARVRRTGDMDAMGEQVAG 232 PDG FGGVVVVS+DP+Y + Y+ +D+G +G +TLVG DG+ R R + +G +AG Sbjct: 184 MPDGSFGGVVVVSLDPEYLSSFYNSVDLGKNGNVTLVGLDGIVRARASAGPTGVGSSLAG 243 Query: 233 GKVYAAMLAQGSGTIEAVSKIDGRERLYAFQKLRDYPLFAAVGIDLEERLAPYYRERERT 292 V AA+ + SG+ S IDG R+Y+FQ+++D PL VG +E A + R R+R Sbjct: 244 SPVMAAIQHRSSGSYTVKSLIDGIPRIYSFQRIKDQPLVVIVGQASDEIFAAFKRNRDRD 303 Query: 293 LMLAALLSVAVLVFNAVLLWLAGSLVRSRREALQANQAKSRFLSNMSHEFRTPLNGVLGY 352 L++ LL+V + + ++ L SR A +A+S FL+ MSHE RTP+NGV+G Sbjct: 304 LLVGGLLTVVIGIITILIARYQAGLAASRDAAEAGTRARSEFLAMMSHEIRTPMNGVIGL 363 Query: 353 SDALREELGESPLAQYAVAIHDSGNRLLDLVNAILEVTELEDRRVAVHLDPANIRELVGQ 412 +D L + A + +S + LL L+N +L+ ++L+ R+ + ++ V Sbjct: 364 ADLLLSADLAPEQRKIATTLRESADYLLQLLNDVLDFSKLDADRLEIEHIEFDLHRSVTA 423 Query: 413 AIARHYPQAQAKGLPLECRIGEDVPQILVCDERKIQRVLDNLISNAVRYTDHGRVMVEV- 471 +A+ KGL L I DVP +V D ++++VL NL+ NA+++T+ G V V+V Sbjct: 424 TAELLVSRAKEKGLQLTTSIAPDVPTYVVGDPARLRQVLFNLVGNALKFTEAGSVHVDVR 483 Query: 472 -ERSGAQQLTM--RIKDTGIGIAASQQNDIFEKFTQADDSPRRSQEGAGLGLTIAQRLVM 528 E LT+ + DTG+GI A +F++F+Q D+S R G GLGL I +RLV Sbjct: 484 AEDLAGPNLTLVFSVADTGVGIPAEAVGRLFKQFSQVDNSISRRFGGTGLGLAICKRLVT 543 Query: 529 LMGGQLVLQSEQHQGSTFSFTLPLQ 553 MGG + +QS+ +GSTF+F++ +Q Sbjct: 544 CMGGDIKVQSKVGEGSTFTFSIQVQ 568 >A5EHF7.1 A5EHF7_BRASB Putative sensor histidine kinase with a response regulator receiver domain Length = 729 Score = 320 bits (821), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 204/569 (35%), Positives = 310/569 (54%), Gaps = 31/569 (5%) Query: 7 QSLPLRFARIDLRV----------ALSLFSLLLICGLWLGAFKELQNSRNNYLDDARRDA 56 +S+PL F R+D V ++ L I +W+G + R A ++ Sbjct: 7 KSMPL-FGRLDRAVDALVRLIGHFGSAVIGLSAIALVWVGIVYTITEERARTEQSALKNG 65 Query: 57 QSLSRLFLEHAYRTIEAADQAALYLRYRYAERGNALNLATEIDNGLVARNVYNL----FS 112 +L+R F E R+I AADQ LY+R YA+ D L ARN L F Sbjct: 66 ANLARAFEEQIIRSIRAADQTLLYVRDSYAKD------PQNFDMSLWARNSQFLSDFSFQ 119 Query: 113 IVDAQGDVVLSSKPFTP----VNLADREHVQVHMQGGQDQLFISKPVLGRVSKKWSLQIT 168 +V D ++ S P ++L DREH +VH G D LFISKP+ GRVS KWS+Q+T Sbjct: 120 VVVIGKDGIMLSSNIDPKMRGLDLHDREHFRVHADGTADFLFISKPIFGRVSNKWSIQLT 179 Query: 169 RRINRPDGGFGGVVVVSMDPQYFTRLYHQIDVGHHGVITLVGADGVARVRRTGDMDAMGE 228 RRI DG FGGVVVVS+DP+Y + Y+ +D+G +G +TLVG DG+ R R + A+G Sbjct: 180 RRIILQDGSFGGVVVVSLDPEYLSSFYNSVDIGKNGNVTLVGTDGIVRARASAGPSAVGS 239 Query: 229 QVAGGKVYAAMLAQGSGTIEAVSKIDGRERLYAFQKLRDYPLFAAVGIDLEERLAPYYRE 288 +AG + A + + SG+ S+IDG R+Y+F++++D PL VG +E + Sbjct: 240 SLAGSPIMANIEQKTSGSYITKSQIDGISRIYSFRRVKDQPLVVVVGQATDEVFSAI--R 297 Query: 289 RERTLMLAALLSVAVLVFNAVLLWLAGSLVRSRREALQANQAKSRFLSNMSHEFRTPLNG 348 +R LM+ LL+V + + ++ L SR A +A+S FL+ MSHE RTP+NG Sbjct: 298 VDRGLMVGTLLTVIIGIITILIARYQAGLAASRDAAEAGTRARSEFLAMMSHEIRTPMNG 357 Query: 349 VLGYSDALREELGESPLAQYAVAIHDSGNRLLDLVNAILEVTELEDRRVAVHLDPANIRE 408 V+G +D L + A + +S + LL L+N +L+ ++L+ R+ + ++ Sbjct: 358 VIGLADLLLSADLAPEQRKIATTLRESADYLLQLLNDVLDFSKLDADRLEIEHIEFDLHR 417 Query: 409 LVGQAIARHYPQAQAKGLPLECRIGEDVPQILVCDERKIQRVLDNLISNAVRYTDHGRVM 468 V +A+ KGL L I DVP +V D ++++VL NL+ NA+++T+ G V Sbjct: 418 SVTATAELLVSRAKEKGLQLTTSIAPDVPNYVVGDPARLRQVLFNLVGNALKFTEAGSVN 477 Query: 469 VEV--ERSGAQQLTM--RIKDTGIGIAASQQNDIFEKFTQADDSPRRSQEGAGLGLTIAQ 524 ++V E LT+ + DTG+GI A +F +F+Q D+S R G GLGL I + Sbjct: 478 IDVRAENLAGPNLTLVFSVADTGVGIPAEAVGRLFRQFSQVDNSISRRFGGTGLGLAICK 537 Query: 525 RLVMLMGGQLVLQSEQHQGSTFSFTLPLQ 553 RLV MGG + +QS+ +GSTF+F++ +Q Sbjct: 538 RLVTCMGGDIKVQSKIGEGSTFTFSIEVQ 566 >B1Y0E3.1 B1Y0E3_LEPCP Histidine kinase EC=2.7.13.3 Length = 589 Score = 282 bits (721), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 208/583 (35%), Positives = 298/583 (51%), Gaps = 45/583 (7%) Query: 3 DRKQQSLPLRF-ARIDLRVALSLF-----SLLLICGLWLGAFKELQNSRNNYLDDARRDA 56 D S P R +R LR L++ S+L++ GL R + AR + Sbjct: 21 DAPPASRPARLVSRWALRFMLAMLAIAWASVLVVIGL---------EYRESMAAQARHN- 70 Query: 57 QSLSRLFLEHAYRTIEAADQAALYLRYRYAERGNA---LNLATEIDNGLVARNVYNLFSI 113 +L+R F E R + A DQA + R R A R A +LA + +A + S+ Sbjct: 71 TNLARAFEEQTVRVVAAVDQATI--RMRDAVRSGAHTLADLAQFANETGMAPTILVQLSL 128 Query: 114 VDAQGDVVLSSKPFTP-------VNLADREHVQVHMQ----GGQ--DQLFISKPVLGRVS 160 V G S P V+L+ REH++VH+ GQ D LFI KPVLG+VS Sbjct: 129 VGPDGR--FSGSNLDPDGSKTGHVDLSTREHIRVHLSPDGAAGQHADGLFIGKPVLGKVS 186 Query: 161 KKWSLQITRRINRPDGGFGGVVVVSMDPQYFTRLYHQIDVGHHGVITLVGADGVARVRRT 220 +W++Q++RRI+ PDG GVVV S+DP YF +Y +++G G +TLVG D R R Sbjct: 187 GRWTIQLSRRIDGPDGRVLGVVVASLDPSYFENVYRSVELGRQGGVTLVGTDLAIRARVM 246 Query: 221 GDMD-AMGEQVAGGKVYAAMLAQGSGTIEAVSKIDGRERLYAFQKLRDYPLFAAVGIDLE 279 GD MG + + Q SG + S +DG ERL + ++ DYPL+ V Sbjct: 247 GDSSLGMGANIGAASPLVSGGWQRSGDYVSASTVDGVERLVGYHRIDDYPLYVLVSSATA 306 Query: 280 ERLAPYYRERERTLMLAALLS----VAVLVFNAVLLWLAGS---LVRSRREALQANQAKS 332 E LA + R L+L ALLS A +F + + L S L+ S A AN AK+ Sbjct: 307 ESLAGWRAMRNTVLLLTALLSAAVIAAAWIFLSNVRRLEASNVALIASEARAQSANHAKT 366 Query: 333 RFLSNMSHEFRTPLNGVLGYSDALREELGESPLAQYAVAIHDSGNRLLDLVNAILEVTEL 392 FL+ +SHE RTPL + G+++ + + + + A I + L L+ IL+ ++ Sbjct: 367 EFLAAISHELRTPLTSIRGFAELMEKRIEQPKFKDQAGMIRRAAEHLNALLTQILDFAKI 426 Query: 393 EDRRVAVHLDPANIRELVGQAIARHYPQAQAKGLPLECRIGEDVPQILVCDERKIQRVLD 452 E + V P IR LV A KGL L +I +DVP+ L+ DE ++++VL+ Sbjct: 427 EAGAMRVGATPVAIRPLVRGTADFFAVSAAEKGLELRVQIADDVPETLLTDELRLKQVLN 486 Query: 453 NLISNAVRYTDHGRVMVEVERSGAQQLTMRIKDTGIGIAASQQNDIFEKFTQADDSPRRS 512 NL+SNA+++T G V +EVER A QL + + DTG GI A Q IFE+F QAD Sbjct: 487 NLLSNAMKFTAGGHVAIEVERD-ATQLRLHVVDTGPGIPAEQHELIFERFRQADSQVAHQ 545 Query: 513 QEGAGLGLTIAQRLVMLMGGQLVLQSEQHQGSTFSFTLPLQEP 555 G GLGL +++ L LMGG L + S +G+ F+ TLPL P Sbjct: 546 HGGTGLGLALSRSLAELMGGTLGVTSTPGEGARFTLTLPLGAP 588 >C5T5I5.1 C5T5I5_ACIDE PAS/PAC sensor signal transduction histidine kinase EC=2.7.13.3 Length = 1425 Score = 270 bits (690), Expect = 4e-70, Method: Compositional matrix adjust. Identities = 194/564 (34%), Positives = 285/564 (50%), Gaps = 37/564 (6%) Query: 20 VALSLFSLLLICGLWLGAFKELQNSRNNYLDDARRDAQSLSRLFLEHAYRTIEAADQAAL 79 V +FS L++ G W L LD R + ++ EH R ++ DQA Sbjct: 857 VVACVFSALVLLGAWATMAALLTWQWQETLDAEMRQNTNTAQALKEHTLRVLDTVDQA-- 914 Query: 80 YLRYRYAERGNALN----LATEIDNGLVARNVYNLFSIVDAQGDVVLSSKPFTP------ 129 R + A R L+ ++ + G+V + + L S V A G S+ P Sbjct: 915 MWRVQSAVRDRQLSGQDLVSIANETGMVPQILTQL-SFVGADGRFQGSN--LDPDGSRSQ 971 Query: 130 -VNLADREHVQVHMQGGQ----------DQLFISKPVLGRVSKKWSLQITRRINRPDGGF 178 VNL DR+H++VH+ Q + LF+S+ +LG+VS ++QI+R++ DG Sbjct: 972 HVNLMDRDHIRVHLLPSQATPSPTGMLQNSLFVSRSLLGKVSGVRTIQISRKVIAEDGTT 1031 Query: 179 GGVVVVSMDPQYFTRLYHQIDVGHHGVITLVGADGVARVRRTGDMDAMGEQVAGGKVYAA 238 GVVV S++P +F +Y +D G G + LVG DG+ RVR G A + + Sbjct: 1032 LGVVVASLNPDHFAEVYRGVDFGEDGGVALVGLDGIIRVRVLGGASANVDAQLPDDLLQT 1091 Query: 239 MLAQGSGTIEAVSKIDGRERLYAFQKLRDYPLFAAVGIDLEERLAPYYRERERTLMLAAL 298 M G AVS DG R+ F ++ DYPL G E AP+ R LML L Sbjct: 1092 MSKTSRGATAAVSS-DGIRRIIGFSRVGDYPLVVLSGTSETEAFAPWRTTRNTVLMLTVL 1150 Query: 299 LSVAVLVFNAVLLW----LA---GSLVRSRREALQANQAKSRFLSNMSHEFRTPLNGVLG 351 LS+AV+ F AV L LA +L +S EA +ANQAKS FL+ MSHE RTPL + G Sbjct: 1151 LSLAVVAFVAVFLGSISRLALSHAALTQSEAEAQRANQAKSEFLAAMSHELRTPLTSIRG 1210 Query: 352 YSDALREELGESPLAQYAVAIHDSGNRLLD-LVNAILEVTELEDRRVAVHLDPANIRELV 410 +++ L E + PL Q A+ G L+ L+ IL++ +E + H +P + +LV Sbjct: 1211 FAE-LMELRSKDPLIQEQSALIRQGAEHLNALLTEILDLARIEAGAMPAHPEPVVLHDLV 1269 Query: 411 GQAIARHYPQAQAKGLPLECRIGEDVPQILVCDERKIQRVLDNLISNAVRYTDHGRVMVE 470 + A AK L L + + PQ LV D K++++L NL+SNA+++T GRV + Sbjct: 1270 HEVSELFRVSAVAKSLALTAAVSDAAPQTLVTDRLKLKQILSNLLSNAIKFTPAGRVEIF 1329 Query: 471 VERS-GAQQLTMRIKDTGIGIAASQQNDIFEKFTQADDSPRRSQEGAGLGLTIAQRLVML 529 V+ Q+ + DTG GI AS IFEKF+Q G GLGL++++ L L Sbjct: 1330 VDACPDGSQVHFHVNDTGPGIPASLHGVIFEKFSQGHARISYQHGGTGLGLSLSRALAEL 1389 Query: 530 MGGQLVLQSEQHQGSTFSFTLPLQ 553 +GG L ++S +GSTF+ +LPL Sbjct: 1390 LGGTLTVRSAVGEGSTFTLSLPLH 1413 Score = 109 bits (273), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 72/235 (30%), Positives = 125/235 (53%), Gaps = 6/235 (2%) Query: 320 SRREALQANQAKSRFLSNMSHEFRTPLNGVLGYSD--ALREELGESPLAQYAVAIHDSGN 377 +R A +A+++KS F++N+SHE RTPL +LG+S+ LR E A ++ IH +G Sbjct: 593 ARDLAEEASRSKSEFVANISHELRTPLQSILGFSELGMLRGRQHEKLAAMFS-DIHAAGQ 651 Query: 378 RLLDLVNAILEVTELEDRRVAVHLDPANIRELVGQAIARHYPQAQAKGLPLECRIGEDVP 437 R+L LVN +L++ ++E A H + ++R+L+ A K L L +G P Sbjct: 652 RMLVLVNDLLDIAKIESTVGAFHFERIDVRDLIDDVAAEMELLLGRKRLDLRLALGR-AP 710 Query: 438 QILVCDERKIQRVLDNLISNAVRYTDHGRVM-VEVERSGAQQLTMRIKDTGIGIAASQQN 496 I D + Q+V+ N+++NAV+++ G + + + +++ D G GI S+ Sbjct: 711 LIAKVDPSRFQQVVRNVLANAVKFSPKGSAIDISASTPDDDFIHIQVCDQGPGIPPSELE 770 Query: 497 DIFEKFTQADDSPRRSQEGAGLGLTIAQRLVMLMGGQLVLQSEQHQGSTFSFTLP 551 +FE F Q+ + R G GLGL I ++++ GG++ + G+ F LP Sbjct: 771 AVFEAFVQSSQT-RDGSGGTGLGLAICRKIITAHGGRINATNVPGGGAMFHIVLP 824 >F0QBD7.1 F0QBD7_ACIAP Integral membrane sensor signal transduction histidine kinase Length = 595 Score = 264 bits (674), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 191/574 (33%), Positives = 293/574 (51%), Gaps = 50/574 (8%) Query: 21 ALSLFSLLL-ICGLWLGAFKELQNSRNNYLDDARRDAQSLSRLFLEHAYRTIEAADQAAL 79 AL + +LLL + W LQ + + RR +L+R+ E R + AADQA L Sbjct: 29 ALVIGTLLLALTATWALVAISLQTKWQDAVQSQRRQNANLARVLEEQTLRVLAAADQATL 88 Query: 80 ----------YLRYRYAERGNALNLATEIDNGLVARNVYNLFSIVDAQGDVVLSSKPFT- 128 + + YA N LA +I L SIV G V S+ T Sbjct: 89 RVAAEVRSGEFTKEDYALFANETGLAPDILTQL---------SIVGPDGRFVGSNLDPTG 139 Query: 129 ----PVNLADREHVQVHMQGGQ----------DQLFISKPVLGRVSKKWSLQITRRINRP 174 +L++REH++VH++ + LFI KPV GR+S + ++Q++R I Sbjct: 140 ARNQDTDLSEREHIRVHLEPSKVPHARTQMSASGLFIGKPVTGRISGRRTMQLSRPIIGR 199 Query: 175 DGGFGGVVVVSMDPQYFTRLYHQIDVGHHGVITLVGAD--GVARVRRT--GDMDAMGEQV 230 +G GVVV S++P YF ++Y +D+G G + L+GAD + RV T G++D + E Sbjct: 200 NGYLHGVVVASLNPSYFEKVYGGVDIGAQGAVVLMGADFGMLTRVIGTQAGNIDQVIEFP 259 Query: 231 AGGKVYAAMLAQGSGTIEAVSKIDGRERLYAFQKLRDYPLFAAVGIDLEERLAPYYRERE 290 + A + GT + VS +DG R+ AF +L YPL V +E LA + R Sbjct: 260 PDHPL--ADTTRRHGTYQRVSHVDGLGRITAFHRLPGYPLTVLVSTADDEALAEWKTMRN 317 Query: 291 RTLMLAALLSVAVLVFNAVLL-------WLAGSLVRSRREALQANQAKSRFLSNMSHEFR 343 T++ A L S A++ A L +L S +A AN+AKS FL+ +SHE R Sbjct: 318 FTMVFAGLFSAALVALCAGFLRGLRQLEQKNVALAASEAQARSANRAKSEFLTAISHELR 377 Query: 344 TPLNGVLGYSDALREELGESPLAQYAVAIHDSGNRLLDLVNAILEVTELEDRRVAVHLDP 403 TPL + G+++ + + L + + A I + L L++ IL++ +++ + + Sbjct: 378 TPLTSIHGFAELMEQRLEQPSYREAAGLIRSAAEHLNTLLSEILDLAKVQAGAMPIVPGD 437 Query: 404 ANIRELVGQAIARHYPQAQAKGLPLECRIGEDVPQILVCDERKIQRVLDNLISNAVRYTD 463 +RELVG + A KGL LE RI DVP +L CD +++++L+NL+SNA+++T Sbjct: 438 HAVRELVGTTVDLFAISAAQKGLTLEKRIAPDVPHMLRCDGLRLKQILNNLLSNALKFTR 497 Query: 464 HGRVMVEVERSGAQQLTMRIKDTGIGIAASQQNDIFEKFTQADDSPRRSQEGAGLGLTIA 523 G V +EV+ + A+ L R+ DTG GI A IFEKF+Q G GLGL ++ Sbjct: 498 EGGVRLEVDTAEARNLRFRVIDTGPGIPADLHEVIFEKFSQGGAEVSTQHGGTGLGLALS 557 Query: 524 QRLVMLMGGQLVLQSEQHQGSTFSFTLPL--QEP 555 + L LMGG+L + SE G+ F+ LP+ QEP Sbjct: 558 RGLAELMGGRLTVASETGHGACFTLELPMPAQEP 591 >A1TRR9.1 A1TRR9_ACIAC Integral membrane sensor signal transduction histidine kinase Length = 595 Score = 252 bits (644), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 178/547 (32%), Positives = 278/547 (50%), Gaps = 45/547 (8%) Query: 46 NNYLDDARRDAQ----SLSRLFLEHAYRTIEAADQAALYLRYR-----YAERGNALNLAT 96 N DA R + +L+R+ E R + AADQA L + ++E+ AL A Sbjct: 52 NTKWQDAVRSQERQNANLARVLEEQTLRVLAAADQATLRVAAEVRSGEFSEQDYAL-FAN 110 Query: 97 EIDNGLVARNVYNLFSIVDAQGDVVLSS-KPFTPVN----LADREHVQVHMQGGQDQ--- 148 E +A ++ SIV G V S+ P N L++REH++VH++ G++ Sbjct: 111 ETG---LAPDILTQLSIVGPDGRFVGSNLDPSAARNQDTDLSEREHIRVHLEPGKEPRAR 167 Query: 149 -------LFISKPVLGRVSKKWSLQITRRINRPDGGFGGVVVVSMDPQYFTRLYHQIDVG 201 LF+ +PV GRVS + ++Q++R I + GVVV S++P YF ++Y +D+G Sbjct: 168 TRMSASGLFVGRPVTGRVSGRRTMQLSRPIVGSNRYLHGVVVASLNPGYFEQVYGSVDIG 227 Query: 202 HHGVITLVGADGVARVRRTG----DMDAMGEQVAGGKVYAAMLAQGSGTIEAVSKIDGRE 257 G + L+GAD R G +D E G + QG T + VS IDG Sbjct: 228 AQGAVALMGADFNVLARVIGAQAESIDKTIEFPPGHPLTDTTRTQG--TYQRVSHIDGLG 285 Query: 258 RLYAFQKLRDYPLFAAVGIDLEERLAPYYRERERTLMLAALLSVAVLVFNAVLLWLAG-- 315 R+ AF ++ YPL V +E LA + R T++ A L S ++ A +L G Sbjct: 286 RITAFHRVPGYPLTVLVSTTDDEALAEWKTMRTFTVVFAGLFSATLIALGAG--FLRGLH 343 Query: 316 -------SLVRSRREALQANQAKSRFLSNMSHEFRTPLNGVLGYSDALREELGESPLAQY 368 +L S +A AN+AKS FL+ +SHE RTPL + G+++ + + L + + Sbjct: 344 QLEQKNLALAASEAQARSANRAKSEFLTAISHELRTPLTSIHGFAELMEQRLEQPSYREA 403 Query: 369 AVAIHDSGNRLLDLVNAILEVTELEDRRVAVHLDPANIRELVGQAIARHYPQAQAKGLPL 428 A I + L L++ IL++ +++ + + +RELVG + A KGL L Sbjct: 404 AGLIRSAAEHLNTLLSEILDLAKVQAGAMPIVPGDHAVRELVGTTVDLFAISAVQKGLTL 463 Query: 429 ECRIGEDVPQILVCDERKIQRVLDNLISNAVRYTDHGRVMVEVERSGAQQLTMRIKDTGI 488 E I VPQ+L CD +++++L+NL+SNA+++T G V +E + + + R+ DTG Sbjct: 464 EMHIAPGVPQVLRCDGLRLKQILNNLLSNALKFTREGGVRLETDTADGHSVRFRVTDTGP 523 Query: 489 GIAASQQNDIFEKFTQADDSPRRSQEGAGLGLTIAQRLVMLMGGQLVLQSEQHQGSTFSF 548 GI A IFEKF+Q G GLGL +++ L LMGG+L + SE QG+ F+ Sbjct: 524 GIPADLHEVIFEKFSQGSADVSTQHGGTGLGLALSRGLAELMGGRLTVASEPGQGACFTL 583 Query: 549 TLPLQEP 555 LP+ P Sbjct: 584 ELPMHPP 590 >A4U3D7.1 A4U3D7_9PROT Signal transduction histidine kinase Length = 576 Score = 239 bits (610), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 171/558 (30%), Positives = 278/558 (49%), Gaps = 35/558 (6%) Query: 21 ALSLFSLLLICGLWLGAFKELQNSRNNYLDDARRDAQSLSRLFLEHAYRTIEAADQAALY 80 A++ F L+ +W+ + L + R L D R D +L+R F EH RTI DQ LY Sbjct: 17 AVAWFGAALLVMVWVAIYASLSSERTRVLADTRADTANLARAFDEHIQRTIAGLDQTLLY 76 Query: 81 LRYRYAERGNALNLATEIDNGLVARNVYNLFSIVDAQGDVVLSSKP-FTPVNLADREHVQ 139 LR + + +L + N ++ + V + +DA G + S+ P F ++L+DREH + Sbjct: 77 LRAEFQQAPGRFDLNRSVANNVILKRVSVQIARIDADGMLADSNVPGFARMDLSDREHFR 136 Query: 140 VHMQGGQDQLFISKPVLGRVSKKWSLQITRRINRPDGGFGGVVVVSMDPQYFTRLYHQID 199 VH +D+LFISKPVLGR S KWS+Q+TRR+ G F GV+VVS+DP Y +Y ID Sbjct: 137 VHKTAVKDELFISKPVLGRASGKWSIQLTRRLEDGHGNFAGVLVVSLDPNYLGDIYGSID 196 Query: 200 VGHHGVITLVGADGVARVRRTGDMDAMGEQVAGGKVYAAMLAQGSGTIEAVSKIDGRERL 259 VG +G I ++G DGV RV G +G+ + GG + A+ Q + T+E+ +DG +R+ Sbjct: 197 VGENGAIAVIGTDGVVRVASHGGGGFLGKSLQGGTILEAVRRQEATTLESAGPLDGIDRI 256 Query: 260 YAFQKLRDYPLFAAVGIDLEERLAPYYRERERTLMLAALLSVAVLVFNAVLL-------W 312 + + L + PL VG E +A Y R L++ A +++A+ L Sbjct: 257 SSLRPLPNVPLSVLVGRSKVEAMAVYDRSVTWHLLIGAAVTLALGAALIALYRMVRAQES 316 Query: 313 LAGSLVRSRREALQANQAKSRFLSNM-------SHEFRTPLNGVLGYSDALREELGESPL 365 +A L + E L + R+++++ +H+ + PL V+ Y+ L + + Sbjct: 317 IAADLAVKKAELLASRVRLRRYVADLERIAEVAAHDLQEPLRRVVAYAQLLSSHVASALD 376 Query: 366 AQ---YAVAIHDSGNRLLDLVN---AILEVTELEDRRVAVHLDPANIRELVGQAIARHYP 419 + Y + D R+ LV A + V ++ D V + A V A+ R Sbjct: 377 DEGRGYVAHVVDGAQRMRKLVKDLEAFVAVDQIPDCDGEVAVSTA-----VSTAMDRLAD 431 Query: 420 QAQAKGLPLECRIGEDVPQILVCDERKIQRVLDNLISNAVRYTDHGR-VMVEVE-RSGAQ 477 Q ++ G + + + +P LV DER + + L+ N++RY R ++ V RS Sbjct: 432 QIRSAGATI---VVDPLPSALV-DERALAEIFTQLLDNSIRYRCESRKPLIHVSARSEGD 487 Query: 478 QLTMRIKDTGIGIAASQQNDIFEKFTQADDSPRRSQEGAGLGLTIAQRLVMLMGGQLVLQ 537 L ++D G GI + +FE F + + L I +R+V MGG++ + Sbjct: 488 CLVFSVRDNGAGIDPRDRIRLFEIFHRLEGIDGGGTGIG---LAIVRRMVEHMGGKVWVD 544 Query: 538 SEQHQGSTFSFTLPLQEP 555 S +GSTFSF+LP ++P Sbjct: 545 STLGEGSTFSFSLPRRKP 562 >B3E5C2.1 B3E5C2_GEOLS Histidine kinase EC=2.7.13.3 Length = 735 Score = 235 bits (599), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 171/535 (31%), Positives = 275/535 (51%), Gaps = 39/535 (7%) Query: 49 LDDARRDAQSLSRLFLEHAYRTIEAADQAALYLRYRYAERGNALNLATEIDNGLVARNVY 108 + +A +QS +R EHA R ADQ+ Y ++ + RG + + + L+A+N Sbjct: 49 ITNAEHQSQSYARALKEHAERAFSEADQSIHYTIHQISNRGGLQSFSRRELSDLLAQNAG 108 Query: 109 NL-----FSIVDAQGDVVLSS--KPFTPVNLADREHVQVHMQGGQDQLFISKPVLGRVS- 160 N+ +I+DA G ++ +S P P ++ R++ + H +LF P+ ++ Sbjct: 109 NIAQIGTIAIIDANGRMLAASGNTPSLPSDITFRDYFKHHRSNPSPELFFGPPIKSIIAG 168 Query: 161 KKWSLQITRRINRPDGGFGGVVVVSMDPQYFTRLYHQIDVGHHGVITL---VGADGVARV 217 +W ++RRIN P G F G+V V+ D YF LY I G +G TL G D + V Sbjct: 169 NRWHFTVSRRINTPAGAFAGIVRVAFDISYFEELYSSIVAGRNGRFTLATTTGGDYLVLV 228 Query: 218 RRTGDMDAMGEQVAGG-KVYAAMLAQGSGTIEAVSKIDGRERLYAFQKLRDYPLFAAVGI 276 + A G++ A + Y A A + S I G R+ ++ +L YP+ A Sbjct: 229 PSEEKVYASGKKTAPFFRTYVAEQAVRTYH-NKKSNIAGEYRIISYHRLDHYPVVAISSF 287 Query: 277 DLEERLAPYYRERERTLMLAALLSVAVLVFNAVL---------LWLAGSLVRSRREALQA 327 ++ A + +E T+ + ++ L+ + L L L++ ++E L+A Sbjct: 288 GRDQATAEW---KETTIKQGIITALLCLLALLLTRILLVQIKQLDLTNRLLQLQQEELRA 344 Query: 328 N--------QAKSRFLSNMSHEFRTPLNGVLGYSDALREELGESPLAQYAVAIHDSGNRL 379 QAKS FL+NMSHE RTP+N ++G + E + Y + ++ L Sbjct: 345 AKETAEAATQAKSEFLANMSHEIRTPMNAIIGLAQLTLETRLDPQQKSYLERLRNASTAL 404 Query: 380 LDLVNAILEVTELEDRRVAV-HLDPANIRELVGQAIARHYPQAQAKGLPLECRIGEDVPQ 438 L ++N IL+ +++E ++ + HL+ N+ +++ + A+ KGL L I +D+PQ Sbjct: 405 LSIINDILDFSKIEAHKIEIAHLE-LNLADILQDGVTLFQTAAKEKGLKLSLEIADDIPQ 463 Query: 439 ILVCDERKIQRVLDNLISNAVRYTDHGRVMVEVERS--GAQQLTMRI--KDTGIGIAASQ 494 L+ D ++ +VL+NLISNAV++T+ G V V E + QQ+ +RI DTGIGI Q Sbjct: 464 HLIGDPLRLGQVLNNLISNAVKFTERGSVTVRAELADRDDQQVIIRILVSDTGIGIDKEQ 523 Query: 495 QNDIFEKFTQADDSPRRSQEGAGLGLTIAQRLVMLMGGQLVLQSEQHQGSTFSFT 549 +F+ FTQAD S R G GLGL+IA+ LV LMGG + L S QGSTF+FT Sbjct: 524 SERLFQPFTQADGSIVRRFGGTGLGLSIARNLVELMGGSITLSSCPDQGSTFAFT 578