BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0065.p (1504 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IR87.1 D8IR87_HERSS Two component hybrid sensor histidine kina... 2887 0.0 A0L2G4.1 A0L2G4_SHESA Putative PAS/PAC sensor protein 659 0.0 Q12NK9.1 Q12NK9_SHEDO CHASE 647 0.0 E0ITH8.1 E0ITH8_9GAMM Multi-sensor hybrid histidine kinase 645 0.0 E0HVC3.1 E0HVC3_9GAMM Multi-sensor hybrid histidine kinase 641 0.0 B8ECP2.1 B8ECP2_SHEB2 Multi-sensor hybrid histidine kinase EC=2.... 627 e-177 E0IR00.1 E0IR00_9GAMM Multi-sensor hybrid histidine kinase 618 e-174 E0HT85.1 E0HT85_9GAMM Multi-sensor hybrid histidine kinase 618 e-174 E6T8U9.1 E6T8U9_SHEB6 Multi-sensor hybrid histidine kinase 616 e-173 A9KUZ6.1 A9KUZ6_SHEB9 Multi-sensor hybrid histidine kinase 616 e-173 >D8IR87.1 D8IR87_HERSS Two component hybrid sensor histidine kinase/response regulator protein EC=2.7.13.1 EC=2.7.13.2 Length = 1524 Score = 2887 bits (7483), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1483/1504 (98%), Positives = 1490/1504 (99%), Gaps = 1/1504 (0%) Query: 1 MTRVTRNTVVFLLITLLFMLAGAATVRYLNERELHDSLAVDSRWIGDDIESLLRRYEHGL 60 MTRVTRNTVVFLLITLLFMLAGAATVRYLNERELHDSLAVDSRWIGDDIESLLRRYEHGL Sbjct: 22 MTRVTRNTVVFLLITLLFMLAGAATVRYLNERELHDSLAVDSRWIGDDIESLLRRYEHGL 81 Query: 61 RGERGAILAIGEHALTRERMLRYMDSRDLATEFPWAGGFGFIRHVPLSARAAYEQQVRQG 120 RGERGAILAIGEHALTRER+LRYMDSRDLATEFPWAGGFGFIRHVPLSARAAYEQQVRQG Sbjct: 82 RGERGAILAIGEHALTRERLLRYMDSRDLATEFPWAGGFGFIRHVPLSARAAYEQQVRQG 141 Query: 121 RRLFPSITQLAENPGELYVIEYIEPIEANRKALGLDIASSQARRSAADHAMLTGRAELTP 180 R LFPSITQLAENPGELYVIEYIEPIEANRKALGLDIASSQARRSAADHAMLTGRAELTP Sbjct: 142 RMLFPSITQLAENPGELYVIEYIEPIEANRKALGLDIASSQARRSAADHAMLTGRAELTP 201 Query: 181 PIHLVQKDGASANAYLFLLPIYAGSVTPPTLHERQEKIIGWAYAPLSVHDIISELSRRWK 240 PIHLVQKDGASANAYLFLLPIYAGSVTPPTLHERQEKIIGWAYAPLSVHDIISELSRRWK Sbjct: 202 PIHLVQKDGASANAYLFLLPIYAGSVTPPTLHERQEKIIGWAYAPLSVHDIISELSRRWK 261 Query: 241 THALEVLIKDAAADGDNVELFRSDGFDALAQDSGLDSALSLYGRTWKLQLRPSTDYRQTH 300 THALEVLIKDAAADGDNVELFRSDGFDALAQDSGLDSALSLYGRTWKLQLRPSTDYRQTH Sbjct: 262 THALEVLIKDAAADGDNVELFRSDGFDALAQDSGLDSALSLYGRTWKLQLRPSTDYRQTH 321 Query: 301 QFVSDRAMLLSCGSLLVLALVIALAYQTYSRREEKLQQAQALLAAVVDSSPDAIVTTDAQ 360 QFVSDRAMLLSCGSLLVLALVIALAYQTYSRREEKLQQAQALLAAVVDSSPDAIVTTDA Sbjct: 322 QFVSDRAMLLSCGSLLVLALVIALAYQTYSRREEKLQQAQALLAAVVDSSPDAIVTTDAL 381 Query: 361 GRISSWNRGAADYLPSSPAQALNTPLAQHPDLRDDLRARAASDASGQTTPHIVSLQGAPV 420 GRISSWNRGAADYLPSSPAQALNTPLAQHPDLR+ L ARAASDASGQTTPHIVSL GAPV Sbjct: 382 GRISSWNRGAADYLPSSPAQALNTPLAQHPDLRE-LDARAASDASGQTTPHIVSLHGAPV 440 Query: 421 RYASAQVFALHDRAGRAVGKAFMLRDITHEKNIERQLQRINEELEWTVQQRTQALHQAKT 480 RYASAQVFALHDRAGRAVGKAFMLRDITHEKNIERQLQRINEELEWTVQQRTQALHQAKT Sbjct: 441 RYASAQVFALHDRAGRAVGKAFMLRDITHEKNIERQLQRINEELEWTVQQRTQALHQAKT 500 Query: 481 MLQTVLNVMPSLVAYWDRHLINHFANAAYERAFQREAGQLNGVYMPDLVGPALFEKALPH 540 MLQTVLNVMPSLVAYWDRHLINHFANAAYERAFQREAGQLNGVYMPDLVGPALFEKALPH Sbjct: 501 MLQTVLNVMPSLVAYWDRHLINHFANAAYERAFQREAGQLNGVYMPDLVGPALFEKALPH 560 Query: 541 IEGVLAGAQQTFERSVDDPVLGARHMLTTYIPEIGDLGEVTGFYVVAHDVTEITHNRNQL 600 I+GVLAGAQQTFERSVDDPVLGARHMLTTYIPEIGDLGEVTGFYVVAHDVTEITHNRNQL Sbjct: 561 IKGVLAGAQQTFERSVDDPVLGARHMLTTYIPEIGDLGEVTGFYVVAHDVTEITHNRNQL 620 Query: 601 SETLAQNQSLLDQVQDANTLLNNVLSSAKGVAIIATDTEGLVTLFNSGAEQMLGYRAEDV 660 SETLAQNQSLLDQVQDANTLLNNVLSSAKGVAIIATDTEGLVTLFNSGAEQMLGYRAEDV Sbjct: 621 SETLAQNQSLLDQVQDANTLLNNVLSSAKGVAIIATDTEGLVTLFNSGAEQMLGYRAEDV 680 Query: 661 VGKLKEEHFSSRPEAALPGQDSHTELLYRRHDGATLPVARQQTSMFDHRQRHLGYLYIAL 720 VGKLKEEHFSSRPEAALPGQDSHTELLYRRHDGATLPVARQQTSMFDHRQRHLGYLYIAL Sbjct: 681 VGKLKEEHFSSRPEAALPGQDSHTELLYRRHDGATLPVARQQTSMFDHRQRHLGYLYIAL 740 Query: 721 DVSLQRQQASALAAARDQLVLAAEVAKLGVWVWDKDSDVLEYNPQVAEIYGFGDRGGAPR 780 DVSLQRQQASALAAARDQLVLAAEVAKLGVWVWDKDSDVLEYNPQVAEIYGFGDRGGAPR Sbjct: 741 DVSLQRQQASALAAARDQLVLAAEVAKLGVWVWDKDSDVLEYNPQVAEIYGFGDRGGAPR 800 Query: 781 VSTYADWRRRVHPDDVDYVEKTLRAGLAVDGDHEPVFRVVRDDGGIRYVQARAYVQRDGA 840 VSTYADWRRRVHPDDVDYVEKTLRAGLAVDGDHEPVFRVVRDDGGIRYVQARAYVQRDGA Sbjct: 801 VSTYADWRRRVHPDDVDYVEKTLRAGLAVDGDHEPVFRVVRDDGGIRYVQARAYVQRDGA 860 Query: 841 GRPVRVICINLDITQRIEFENNLVDARLKAEQANSAKSLFLASVSHEIRTPMNGVLGMIQ 900 GRPVRVICINLDITQRIEFENNLVDARLKAEQANSAKSLFLASVSHEIRTPMNGVLGMIQ Sbjct: 861 GRPVRVICINLDITQRIEFENNLVDARLKAEQANSAKSLFLASVSHEIRTPMNGVLGMIQ 920 Query: 901 LLQRTQPLPAQQDYLDKAEISAKSLLNLLNDLLDFSKMDAKQLQLDPQAFELERFGHDLA 960 LLQRTQPLPAQQDYLDKAEISAKSLLNLLNDLLDFSKMDAKQLQLD QAFELERFGH+LA Sbjct: 921 LLQRTQPLPAQQDYLDKAEISAKSLLNLLNDLLDFSKMDAKQLQLDLQAFELERFGHNLA 980 Query: 961 AVLAGSPPQAGVRLHIALDPQLPRRLVGDAHRLQQVLVNLAGNALKFTHQGHIDVHFTRL 1020 AVLAGSPPQAGV LHIALDPQLPRRLVGDAHRLQQVLVNL GNALKFTHQGHIDVHFTRL Sbjct: 981 AVLAGSPPQAGVSLHIALDPQLPRRLVGDAHRLQQVLVNLTGNALKFTHQGHIDVHFTRL 1040 Query: 1021 DPLPGRTVALRVEVSDTGIGIAADRLDDIFDAFTQAEASTTRRYGGTGLGLAISKHLVGL 1080 DPLPGRTVALRVEVSDTGIGIAADRLDDIFDAFTQAEASTTRRYGGTGLGLAISKHLVGL Sbjct: 1041 DPLPGRTVALRVEVSDTGIGIAADRLDDIFDAFTQAEASTTRRYGGTGLGLAISKHLVGL 1100 Query: 1081 MGGQLQVSSEPGRGSRFWFDLQLAVDDDSVLGPAAADDAARPQPLQAASHTAGSRAPETA 1140 MGGQLQVSSEPGRGSRFWFDLQLAVDDDSVLGPAAADDAARPQPLQAASHTAGSRAPETA Sbjct: 1101 MGGQLQVSSEPGRGSRFWFDLQLAVDDDSVLGPAAADDAARPQPLQAASHTAGSRAPETA 1160 Query: 1141 RAAPDAQCLQGVQILLVEDNPVNRQVASELLALSGAQVTCADSGSMGVAMACDPARHFDL 1200 R+APDAQCLQGVQILLVEDNPVNRQVASELLALSGAQVTCADSGSMGVAMACDPARHFDL Sbjct: 1161 RSAPDAQCLQGVQILLVEDNPVNRQVASELLALSGAQVTCADSGSMGVAMACDPARHFDL 1220 Query: 1201 VLMDLQMPGMDGIEATRRIRGQYELRGLPILAMTANASPEDKQRCIEAGMAGHIAKPIDI 1260 VLMDLQMPGMDGIEATRRIRGQYELRGLPILAMTANASPEDKQRCIEAGMAGHIAKPIDI Sbjct: 1221 VLMDLQMPGMDGIEATRRIRGQYELRGLPILAMTANASPEDKQRCIEAGMAGHIAKPIDI 1280 Query: 1261 ATLIPVLLAHLHHERPVPEAASPPAPQDLAEDRLCVEDYSSILHRFQQASDIYRTTLDAA 1320 ATLIPVLLAHLHHERPVPEAA PQDLA+DRL VEDYSSILHRFQQASDIYRTTLDAA Sbjct: 1281 ATLIPVLLAHLHHERPVPEAAPQAVPQDLADDRLSVEDYSSILHRFQQASDIYRTTLDAA 1340 Query: 1321 GPELERLLAQYCAALAMSPVRAQEAMAALAQASHALRGVTATIGARGLAAYFGALEQRCR 1380 GPELERLLAQYCAALAMSP +AQEAMAALAQASHALRGVTATIGARGLAAYFGALEQRCR Sbjct: 1341 GPELERLLAQYCAALAMSPEQAQEAMAALAQASHALRGVTATIGARGLAAYFGALEQRCR 1400 Query: 1381 QAMAGRTPDLDWLERCRTEMDACQHDAMLVRQRLVMQALRPPASDAGPAAAALATVAASD 1440 QAMAGRTPDLDWLERCRTEMDACQHDAMLVRQRLVMQALRPPASDAGPAAAALATVAASD Sbjct: 1401 QAMAGRTPDLDWLERCRTEMDACQHDAMLVRQRLVMQALRPPASDAGPAAAALATVAASD 1460 Query: 1441 FPDRQRLRELLLSNNLEALDLIETLGKRHGLTQQEPYRQLNRLIEKLDFAAALTCLDHHF 1500 FPDRQRLRELLLSNNLEALDLIETLGKRHGLTQQEPYRQLNRLIEKLDFAAALTCLDHHF Sbjct: 1461 FPDRQRLRELLLSNNLEALDLIETLGKRHGLTQQEPYRQLNRLIEKLDFAAALTCLDHHF 1520 Query: 1501 GDAT 1504 GDAT Sbjct: 1521 GDAT 1524 >A0L2G4.1 A0L2G4_SHESA Putative PAS/PAC sensor protein Length = 1626 Score = 659 bits (1700), Expect = 0.0, Method: Compositional matrix adjust. Identities = 459/1335 (34%), Positives = 683/1335 (51%), Gaps = 107/1335 (8%) Query: 12 LLITLLFMLAGAATVRYLNERELHDSLAVDSRWIGDDIESLLRRYEHGLRGERGAILAIG 71 LL+ L F A V +N + + +L ++ I +++ + + Y++GLRG RG IL G Sbjct: 18 LLVGLFFSAVLAWQVSRINAQTISQALEERAQQISENVTNRITLYQYGLRGARGMILTAG 77 Query: 72 EHALTRERMLRYMDSRDLATEFPWAGGFGFIRHVPLSARAAYEQQVRQGRRLFPSITQLA 131 E ++R Y +RD+ EFP A GFGFIR VP A + +V+ I QL Sbjct: 78 EDHISRSMFQNYSLTRDVDEEFPGARGFGFIRRVPKENEAQFLARVKSMDWPDFHIRQLN 137 Query: 132 ENPGELYVIEYIEPIEANRKALGLDIASSQARRSAADHAMLTGRAELTPPIHLVQKDGAS 191 N GE Y+IEYIEP++ N+ A+GLDIAS R+ AAD A+L+G +++ PI LVQ G Sbjct: 138 PNEGEKYLIEYIEPLDRNKAAVGLDIASESHRKEAADRALLSGAVQISAPITLVQATGKP 197 Query: 192 ANAYLFLLPIYAGSVTPPTLHERQEKIIGWAYAPLSVHDIISELSRRWKTHALEVLIKDA 251 ++L LLP+Y P T ER + GW+YAPL +I++ LS K L ++ D Sbjct: 198 LQSFLILLPVYRSGTVPKTPEERLAQGFGWSYAPLVTTEILTGLSLHQKMTKL--MLSDV 255 Query: 252 AADGDNVELFRSDGFD-ALAQDSGLDSALSLYGRTWKLQLRPSTDYRQTHQFVSDRAMLL 310 + + F + D + D S +++GR W+ ++ + ++ +L Sbjct: 256 TDEQQPINFFETHANDLSELSDYSYKSTKTIFGRHWQFEVIAYPAFIKSLHLNKPSLVLF 315 Query: 311 S-CGSLLVLALVIALAYQTYSRREEKLQQAQALLAAVVDSSPDAIVTTDAQGRISSWNRG 369 S C L+LA +IA+ + R+++ L + QA A++++ S D I++ D G I+SWN+G Sbjct: 316 SGCLFSLLLAALIAMWSLSLQRKQQVLAE-QARRASMLEHSLDGIISYDLAGNITSWNQG 374 Query: 370 AADYLPSSPAQALNTP---LAQHPDLRDDLRARAASDASGQTTPHIVSLQ----GAPVRY 422 A + + L P L P + + +A A +G+T + VS G+ + Sbjct: 375 AERLFGFTEPETLGLPSSELIVPPSIVLEEQALFAEVLAGKTVLNRVSRHQRADGSNLS- 433 Query: 423 ASAQVFALHDRAGRAVGKAFMLRDITHEKNIERQLQRINEELEWTVQQRTQALHQAKTML 482 S ++D G VG + +RDIT +++ ER + +N LE V +RT AL QA Sbjct: 434 TSTTALPIYDEHGDIVGLSQTIRDITAQQDAERHILNLNASLERQVAKRTHALQQALLEN 493 Query: 483 QTVLNVMPSLVAY----WDRHLINHFANAAYERAFQRE--AGQLNGVYMPDLVGPALFEK 536 Q +L+ + + Y D +++ + + RE G+ + V A ++ Sbjct: 494 QALLDTINQQLHYSVTDLDGVILDVNEHFCLISGYAREELVGKTHAVLKSGEHDAAFWKA 553 Query: 537 ALPHIEGVLAGAQQTFERSVDDPVLGARHMLTTYIPEIGDL-GEVTGFYVVAHDVTEITH 595 I+ + + R D + T I + D G+V F + D+TE Sbjct: 554 MWEQIKAGKSWHGEICNRGKDQQL----KWFDTVIGSVFDEHGQVERFVALQTDITE--- 606 Query: 596 NRNQLSETLAQNQSLLDQVQDANTLLNNVLSSAKGVAIIATDTEGLVTLFNSGAEQMLGY 655 LAQ + TLL NVL +A + IIA D +G++T+FN GAE+ML Y Sbjct: 607 ------RKLAQIEK-----NRIATLLTNVLDAASEMTIIAADPQGIITIFNRGAERMLWY 655 Query: 656 RAEDVVGKLKEEHFSSRPEAA-------------LPGQDSHTE-----------LLYRRH 691 AE+++GK F E A + G D+ Y R Sbjct: 656 SAEEIIGKTTPAPFHIADEIAARAAELSVEYGQKIQGFDTFVHKAREEGSETRTWTYVRK 715 Query: 692 DGATLPVARQQTSMFDHRQRHLGYLYIALDVSLQRQQASALAAARDQLVLAAEVAKLGVW 751 DG+ LP++ T+M + LGYL I +D+S Q AL A + L AAEVAKLG+W Sbjct: 716 DGSQLPISLSVTAMRGNDGEILGYLGIGVDISQIVAQQEALLTASNHLSKAAEVAKLGIW 775 Query: 752 VWDKDSDVLEYNPQVAEIYGFGDRGGAPRVSTYADWRRRVHPDDVDYVEKTLRAGLAVDG 811 W+ + L++N ++ +Y + +S Y WR RVHPDDV E+TL+ + D Sbjct: 776 TWNLLDNSLQWNDRMFAMYDQPESLKQQGLS-YEHWRMRVHPDDVIEAEETLKRAVEHDE 834 Query: 812 DHEPVFRVVRDDGGIRYVQARAYVQRDGAGRPVRVICINLDITQRIEFENNLVDARLKAE 871 +EP+FR++ DG +RYVQA A ++RD G +RVI IN+DIT + + E L +A+ +A+ Sbjct: 835 PYEPIFRILTTDGEVRYVQAAAKIERDRQGHVIRVIGINIDITAQRQLEKTLRNAKQEAD 894 Query: 872 QANSAKSLFLASVSHEIRTPMNGVLGMIQLLQRTQPLPAQQDYLDKAEISAKSLLNLLND 931 AN+AKS FLA++SHEIRTPMN VLGM+QL+Q T QQ Y+ KA+ +AKSLL LLND Sbjct: 895 TANAAKSAFLANMSHEIRTPMNAVLGMLQLMQYTALSVQQQGYVTKAQTAAKSLLGLLND 954 Query: 932 LLDFSKMDAKQLQLDPQAFELERFGHDLAAVLAGSPPQAGVRLHIALDPQLPRRLVGDAH 991 +LDFSK+DA +L+LD +E DLA VL+ + + V + LD LP L+ D Sbjct: 955 ILDFSKIDAGKLKLDLHPCSIELLMRDLAVVLSANHGNSDVEVMFDLDSALPAWLLADQL 1014 Query: 992 RLQQVLVNLAGNALKFTHQGHIDVHFTRLDPLPGRTVALRVEVSDTGIGIAADRLDDIFD 1051 RLQQ+L+NLAGNALKFT G + V L +V ++ + D+GIGI+ ++++ IF Sbjct: 1015 RLQQILINLAGNALKFTPHGQVIVGLECLRH-EAESVTVQFSIVDSGIGISEEQIERIFT 1073 Query: 1052 AFTQAEASTTRRYGGTGLGLAISKHLVGLMGGQLQVSSEPGRGSRFWFDLQLAVDDDSVL 1111 F QAE+ST+RR+GGTGLGLAISK LV LMGGQLQV+S+ G GSRFWFDL V + Sbjct: 1074 GFEQAESSTSRRFGGTGLGLAISKRLVELMGGQLQVTSKVGVGSRFWFDLTFPVME---- 1129 Query: 1112 GPAAADDAARPQPLQAASHTAGSRAPETARAAPDAQCLQGVQILLVEDNPVNRQVASELL 1171 A P A L G +IL+V+DN + ++ S++L Sbjct: 1130 ----------------------------VEANPRAD-LSGYRILVVDDNQITTEILSKIL 1160 Query: 1172 ALSGAQVTCADSGSMG---VAMACDPARHFDLVLMDLQMPGMDGIEATRRIRGQYELRGL 1228 + G V A G V A A+ FD+VLMD +MP +DG++ ++ Sbjct: 1161 SDYGCVVETASGGYQAIEKVKQATANAQQFDVVLMDWRMPDIDGLQTAEMLKNAGTGSYT 1220 Query: 1229 PILAMTANASPE---DKQRCIEAGMAGHIAKPIDIATLIPVLLAHLHHERPVPEAASPPA 1285 P++ M E + Q + KP+ L +L + E +A P Sbjct: 1221 PLVVMLTAYGHEVIAESQHINNVPFVNFLTKPVTSQILAEAVLNAI--EGKTMDANPKPR 1278 Query: 1286 PQDL--AEDRLCVED 1298 Q L L VED Sbjct: 1279 SQRLLAGLTLLVVED 1293 Score = 171 bits (432), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 122/363 (33%), Positives = 181/363 (49%), Gaps = 23/363 (6%) Query: 1140 ARAAPDAQ-CLQGVQILLVEDNPVNRQVASELLALSGAQVTCADSGSMGVAMACDPARHF 1198 A P +Q L G+ +L+VEDN +NR+V ELL GA V A+ G GV D F Sbjct: 1273 ANPKPRSQRLLAGLTLLVVEDNQLNREVIDELLTYEGATVVLAEGGIEGVTQVLDSGDMF 1332 Query: 1199 DLVLMDLQMPGMDGIEATRRIRGQYELRGLPILAMTANASPEDKQRCIEAGMAGHIAKPI 1258 D V+MD+QMP +DG+EATRRIR LPILAMTANAS DKQ C+EAGM H++KPI Sbjct: 1333 DAVIMDMQMPDIDGLEATRRIRADGRFDQLPILAMTANASQADKQECLEAGMNAHVSKPI 1392 Query: 1259 DIATLIPVLLAHLHHER---PVPEAASPPAPQDLAEDRLCVEDYSSILHRFQQASDIYRT 1315 D+ L+P +L + + PE+ A +L E ++D IL RF + Sbjct: 1393 DMQQLLPNILRLVGRDAAQFAEPESMHLDAQHNL-EGETLLDDIRLILRRFGGNQVFFEK 1451 Query: 1316 TLDAAGPELERLLAQYCAALAMSPVRAQEAMAALAQASHALRGVTATIGARGLAAYFGAL 1375 + PE+ + L+ + + A A SHA++G+ + GAR LA + L Sbjct: 1452 MASSFAPEMIKQLSLFKQSTKTFD------YATTAAISHAIKGIASNFGARRLAVHAAFL 1505 Query: 1376 EQRCRQAMAGRTPDLDWLERCRTEMDAC--QHDAMLVRQRLVMQALRPPASDAGPAAAAL 1433 E++ +Q W + + ++ Q L + +L + +S++ + Sbjct: 1506 EKQFKQEGLELLEIKRWTDTLESLINQSIEQLSGFLPKTQLK----QSQSSESANGVVDI 1561 Query: 1434 ATVAASDFPDRQRLRELLLSNNLEALDLIETLGKRHGLTQQEPYRQLNRLIEKLDFAAAL 1493 +V A + L LL NNLEA+ L++ L K L+Q + +LN ++ L F AL Sbjct: 1562 QSVRA----ELDNLASLLQENNLEAVTLVDKLAK--PLSQHPQWTELNGQVQSLAFMQAL 1615 Query: 1494 TCL 1496 L Sbjct: 1616 ETL 1618 >Q12NK9.1 Q12NK9_SHEDO CHASE Length = 1659 Score = 647 bits (1668), Expect = 0.0, Method: Compositional matrix adjust. Identities = 427/1265 (33%), Positives = 679/1265 (53%), Gaps = 109/1265 (8%) Query: 9 VVFLLITLLFMLAGAATVRYLNERELHDSLAVDSRWIGDDIESLLRRYEHGLRGERGAIL 68 +VF L L LA + V N+R + +L +++ I + + Y++GLR RG+IL Sbjct: 16 LVFTL-GLAISLATSLWVHDKNQRFITQALEENTQDISQRVIERVTLYQYGLRSARGSIL 74 Query: 69 AIGEHALTRERMLRYMDSRDLATEFPWAGGFGFIRHVPLSARAAYEQQVRQGRRLFPSIT 128 GE ++RE Y D+RD+ EFP A GFGFIR V A++ +V+ SI Sbjct: 75 TAGEQGISREIFKGYSDTRDIDIEFPGARGFGFIRRVKPIDEASFIAKVKHAGWPDFSIR 134 Query: 129 QLAENPGELYVIEYIEPIEANRKALGLDIASSQARRSAADHAMLTGRAELTPPIHLVQKD 188 QL + E +VIE +EP+E N A+GLDIAS R AA A+L+G+ L+ PI LVQ Sbjct: 135 QLTPHDNERFVIELVEPVERNMAAIGLDIASETNRYQAAYQALLSGKVHLSGPITLVQAT 194 Query: 189 GASANAYLFLLPIYAGSVTPPTLHERQEKIIGWAYAPLSVHDIISELSRRWKTHALEVLI 248 G ++L LLPIY P T+ R+ + GW+YAPL + +++ +L+ +T LE + Sbjct: 195 GNPQQSFLILLPIYRTGNIPETVKLRKAEGFGWSYAPLVIDEVLEDLNLTQETTKLE--L 252 Query: 249 KDAAADGDNVELFRSDGFDALAQDSGLDSALS--LYGRTWKLQLRPSTDYRQTHQFVSDR 306 KD + + V +++ FD A+ S + LS ++GR W + + + ++ ++ Sbjct: 253 KDVTDNSNPVLFYQTHAFDT-AKLSRYSTTLSTNIFGRQWTISVSAYPVFIESLH-LTRP 310 Query: 307 AMLLSCGSLLVLALVIALAYQTYSRREEKLQQAQ-ALLAAVVDSSPDAIVTTDAQGRISS 365 +++L+ G L+ L + +A+ + ++++++L A+ A A +++ S DAI++ D++G I+ Sbjct: 311 SLVLAYGLLMSLLFAVLMAFYSRNKQQKRLLDAENARRANILEHSLDAIISYDSEGLITG 370 Query: 366 WNRGAAD---YLPSSPAQALNTPLAQHPDLRDDLRARAASDASGQTTPHIVSLQGAPVRY 422 WN+GA Y Q N L ++ + SG+ + V + + Sbjct: 371 WNQGAEHIFGYTKDEVMQGANLGLIVPAANKEIEWTQFKQVLSGEAIQNAVGVHHDKEQN 430 Query: 423 ---ASAQVFALHDRAGRAVGKAFMLRDITHEKNIERQLQRINEELEWTVQQRTQALHQAK 479 S +++ G VG + +RDIT ++ ERQ+ +N LE V RTQAL Sbjct: 431 KLSTSMTALPIYNHVGVIVGVSQTIRDITAAQDAERQIHELNASLERKVHLRTQALEHVV 490 Query: 480 TMLQTVLNVMPSLVAYWDRHL------IN-HFANAAYERAFQREAGQLNGVYMPDLVG-- 530 +T+ + + + Y + L +N +F A+ + RE QL G+ + Sbjct: 491 AENKTLFDTIDQQLLYSEIDLQGIILAVNDNFCEAS---GYSRE--QLVGLSHLQVSSGE 545 Query: 531 -PALFEKALPHIEGVLAGAQQTFERSVDDPVLGARHMLTTYIPEIGDLGEVTGFYVVAHD 589 LF + L + + +G E D + T P + F +A D Sbjct: 546 HDKLFWQRLWN--KIKSGKPWHGEICTLDSKGEPKWFDTVIAPIFDKQKNIERFVSLATD 603 Query: 590 VTEITHNRNQLSETLAQNQSLLDQVQDANTLLNNVLSSAKGVAIIATDTEGLVTLFNSGA 649 +TE + + L +N+ LL+NVL +A VAIIATD G++++FN GA Sbjct: 604 ITE------RKNAQLEKNK--------VGALLSNVLFAASEVAIIATDETGIISIFNRGA 649 Query: 650 EQMLGYRAEDVVGKLKEEHFSSRPEAALPGQDSHTE------------------------ 685 E++LGY +++VGK+ F E L G + E Sbjct: 650 ERLLGYHRDELVGKISPAIFHLTQEVMLRGDELSAEHGIEIRGFEAFIYHAKHKGPETRR 709 Query: 686 LLYRRHDGATLPVARQQTSMFDHRQRHLGYLYIALDVSLQRQQASALAAARDQLVLAAEV 745 Y R DG+ V+ ++M D + LGYL +A ++ L +Q L + QL AAEV Sbjct: 710 WTYVRKDGSECQVSLSVSAMRDTQGNLLGYLGVATNIDLMLKQQEELVSTSTQLTQAAEV 769 Query: 746 AKLGVWVWDKDSDVLEYNPQVAEIYGFGDRGGAPRVSTYADWRRRVHPDDVDYVEKTLRA 805 A+LG+W W+ ++++L++N ++ IY + +S Y W R+HPDDVD ++ L+A Sbjct: 770 AELGIWTWEIETNILDWNERMFAIYDYPSSLNHNGLS-YQHWLDRLHPDDVDMAQEKLKA 828 Query: 806 GLAVDGDHEPVFRVVRDDGGIRYVQARAYVQRDGAGRPVRVICINLDITQRIEFENNLVD 865 + G+++P+FRV+R +RYVQ A+V RD G+ ++++ IN DIT++ E E+ L Sbjct: 829 AIEGTGEYDPIFRVIRPSDEVRYVQGGAHVIRDRFGKALKLLGINRDITEQRELEHTLRR 888 Query: 866 ARLKAEQANSAKSLFLASVSHEIRTPMNGVLGMIQLLQRTQPLPAQQDYLDKAEISAKSL 925 A+ +A+ ++AKS FLA++SHEIRTPMN +LGM+QL+Q T P QQDY+ K E++A+SL Sbjct: 889 AKEEADATSAAKSAFLANMSHEIRTPMNAILGMLQLVQHTDMTPQQQDYVSKTEVAAQSL 948 Query: 926 LNLLNDLLDFSKMDAKQLQLDPQAFELERFGHDLAAVLAGSPPQAGVRLHIALDPQLPRR 985 L LLND+LDFSK+DA +L +D LE +LA +LA + + + + LDP +P Sbjct: 949 LGLLNDILDFSKIDAGKLNVDLHPCSLEEIMRELAVLLAANMRRKHIEVLFDLDPSIPEL 1008 Query: 986 LVGDAHRLQQVLVNLAGNALKFTHQGHIDVHFTRLDPLPGRTVALRVEVSDTGIGIAADR 1045 ++ D RLQQVL+NLAGNA+KFT QGH+ + L L V LR+ V+DTGIGI + Sbjct: 1009 VLADKQRLQQVLLNLAGNAIKFTAQGHVILQVFNL-KLSSHKVRLRISVADTGIGINVSQ 1067 Query: 1046 LDDIFDAFTQAEASTTRRYGGTGLGLAISKHLVGLMGGQLQVSSEPGRGSRFWFDLQLAV 1105 LD IF F QAE+ST+RR+GGTGLGLAI+K LV LMG +L+V S+ G+GSRFWFD++ + Sbjct: 1068 LDKIFQGFMQAESSTSRRFGGTGLGLAITKRLVELMGAELEVESQEGQGSRFWFDIEFEL 1127 Query: 1106 DDDSVLGPAAADDAARPQPLQAASHTAGSRAPETARAAPDAQCLQGVQILLVEDNPVNRQ 1165 + P+ ++ T +R ++LLV+D+ ++R+ Sbjct: 1128 VE---------------TPITKSTLTLNNR-----------------RVLLVDDSAMSRK 1155 Query: 1166 VASELLALSGAQVTCADSGSMGVAM---ACDPARHFDLVLMDLQMPGMDGIEATRRIRGQ 1222 + + L GA+V A G + + + + + FD V+MD +MP ++G+EA RI Sbjct: 1156 IVANTLVTHGAEVVEASGGLEALTLIEQSLEEEKAFDAVVMDWRMPELNGLEAAERI--- 1212 Query: 1223 YELRG 1227 +EL G Sbjct: 1213 HELCG 1217 Score = 155 bits (392), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 98/269 (36%), Positives = 135/269 (50%), Gaps = 44/269 (16%) Query: 1149 LQGVQILLVEDNPVNRQVASELLALSGAQVTCADSGSMGVAMACDPARHFDLVLMDLQMP 1208 LQG+ IL+VEDN +NRQV ELL L GA VT A+ G GV D FD+V+MD+QMP Sbjct: 1284 LQGLSILVVEDNALNRQVIDELLKLQGAIVTLAEGGIEGVKQVTDQGMDFDIVIMDMQMP 1343 Query: 1209 GMDGIEATRRIRGQYELRGLPILAMTANASPEDKQRCIEAGMAGHIAKPIDIATLIPVL- 1267 +DG+EATR IR LPILAMTANAS D++ C+ AGM HI KP+D++ L+P + Sbjct: 1344 DIDGLEATRLIRADGRFEHLPILAMTANASAIDRENCLRAGMNDHIGKPVDMSELVPRIL 1403 Query: 1268 --------------LAHLH-----------------HERPVPEAASPP--APQDLAEDRL 1294 LA+ H +R E+ S PQD+A Sbjct: 1404 TLTRDEYSISGNNSLANSHSADNNPANNNSANISAEQDRLATESISTERVMPQDVA---- 1459 Query: 1295 CVEDYSSILHRFQQASDIYRTTLDAAGPELERLLAQYCAALAMSPVRAQEAMAALAQASH 1354 +ED SSIL RF + + E+ L A + ++ +A H Sbjct: 1460 ILEDTSSILRRFGGEMSFFIDVKQSFVSEMMLQLGLLTTAFEQADLQTASIVA------H 1513 Query: 1355 ALRGVTATIGARGLAAYFGALEQRCRQAM 1383 ++G + +GA+ LAA+ LE C+Q + Sbjct: 1514 TIKGTASNLGAKRLAAFGAQLELECKQGL 1542 >E0ITH8.1 E0ITH8_9GAMM Multi-sensor hybrid histidine kinase Length = 1629 Score = 645 bits (1665), Expect = 0.0, Method: Compositional matrix adjust. Identities = 454/1283 (35%), Positives = 664/1283 (51%), Gaps = 117/1283 (9%) Query: 29 LNERELHDSLAVDSRWIGDDIESLLRRYEHGLRGERGAILAIGEHALTRERMLRYMDSRD 88 +N + + +L ++ I +++ + + Y++GLRG RG+IL+ GE+ ++R RY SRD Sbjct: 35 MNAQTIGQALRENTEQISENVLNRITLYQYGLRGARGSILSAGEYGISRASFHRYSLSRD 94 Query: 89 LATEFPWAGGFGFIRHVPLSARAAYEQQVRQGRRLFPSITQLAENPGELYVIEYIEPIEA 148 + EFP A GFGFIR VP S AA+ + + +I QL + GE YVIEYIEPI+ Sbjct: 95 VDQEFPGARGFGFIRRVPNSDEAAFLTRAKNDDWPDFNIRQLTPHSGEKYVIEYIEPIDR 154 Query: 149 NRKALGLDIASSQARRSAADHAMLTGRAELTPPIHLVQKDGASANAYLFLLPIYAGSVTP 208 NR A+GLD+AS R++AAD AML+G L+ PI LVQ ++L L PIY P Sbjct: 155 NRAAIGLDVASEAHRKAAADAAMLSGEVRLSAPITLVQATRKPLQSFLILQPIYRTISVP 214 Query: 209 PTLHERQEKIIGWAYAPLSVHDIISELSRRWKTHALEVLIKDAAADGDNVELFRSDGFDA 268 T ER GW+YAPL +++++ L+ K L L+ D + F + DA Sbjct: 215 KTPQERLAAGYGWSYAPLVTNEVLTGLALNQKMTKL--LLSDITQTERPISFFETHPDDA 272 Query: 269 LAQDSGLDSALS--LYGRTWKLQLRPSTDYRQTHQFVSDRAMLLSCGSLLVLALVIALAY 326 + S L+ ++GR W++++ + Q+ +LLS L +L + Sbjct: 273 -SPLSAYSHTLTKEIFGRKWQVEVIAYPAFIQSLHLNQPSLVLLSGSLLSLLLAAFIAIW 331 Query: 327 QTYSRREEKLQQAQALLAAVVDSSPDAIVTTDAQGRISSWNRGAADYLPSSPAQAL---N 383 +R++++Q QA A++++ S DAI++ D G I+SWN+GA + + + + Sbjct: 332 SISLQRKQQVQLEQARRASMLEHSLDAIISYDLTGNITSWNQGAEEIFGYTQTDVIGHSS 391 Query: 384 TPLAQHPDLRDDLRARAASDASGQTTPHIVSL---QGAPVRYASAQVFALHDRAGRAVGK 440 L P + + + A SG+T + +S Q S ++D VG Sbjct: 392 CDLIIPPSIVLEEQVLFAEVFSGKTVLNQISTHQRQNGSHVSTSTTSLPIYDEDSAIVGL 451 Query: 441 AFMLRDITHEKNIERQLQRINEELEWTVQQRTQALHQAKTMLQTVLNVMPSLVAYW---- 496 + +RDIT ++ ER + +N LE V +RT AL QA QT+L+ + + Y Sbjct: 452 SQTIRDITTQQEAERYILSLNARLEQEVTKRTNALQQALLENQTLLDTINQQLLYSATDP 511 Query: 497 DRHLINHFANAAYERAFQREA--GQLNGVYMPDLVGPALFEKALPHIEGVLAGAQQTFER 554 + ++ N + + R+ G+ + + A + I+ L+ + R Sbjct: 512 NGVILEVNDNFCHVSGYSRKQLLGETHAILNSGEHDAAFWRTMWTQIKSGLSWHGEICNR 571 Query: 555 SVDDPVLGARHMLTTYI-----PEIGDLGEVTGFYVVAHDVTEITHNRNQLSETLAQNQS 609 RH + + P + G + F + D+TE LAQ + Sbjct: 572 D--------RHQMLKWFDTVIGPVFNENGNIERFVALRTDITE---------RKLAQIEK 614 Query: 610 LLDQVQDANTLLNNVLSSAKGVAIIATDTEGLVTLFNSGAEQMLGYRAEDVVG------- 662 +LL NVL +A ++IIATD +G++T+FN GAEQ+LGY A D++G Sbjct: 615 -----NKLGSLLTNVLDAASEMSIIATDKKGVITIFNRGAEQLLGYAAVDMIGLSTPAPL 669 Query: 663 KLKEE------HFSSRPEAALPGQD----------SHTELL-YRRHDGATLPVARQQTSM 705 L EE SS + G D S T Y R D + V+ T+M Sbjct: 670 HLPEEVAARSAELSSEYGEDIQGFDVFVYKARTLGSETRTWTYVRKDTSQCQVSLSVTAM 729 Query: 706 FDHRQRHLGYLYIALDVSLQRQQASALAAARDQLVLAAEVAKLGVWVWDKDSDVLEYNPQ 765 D+ +GYL IA+D+S QQ AL A + L AAEVAKLG+W WD + LE+N + Sbjct: 730 LDNVGEIIGYLGIAIDISQVLQQQKALITASNHLSKAAEVAKLGIWSWDLRDNSLEWNER 789 Query: 766 VAEIY----GFGDRGGAPRVSTYADWRRRVHPDDVDYVEKTLRAGLAVDGDHEPVFRVVR 821 + IY D+G TY WR R+H DD+D+ E L+A + ++P+FRVVR Sbjct: 790 MFAIYDHPLSLQDKG-----LTYEHWRMRIHSDDIDFAEAKLKAAIEEKDQYDPIFRVVR 844 Query: 822 DDGGIRYVQARAYVQRDGAGRPVRVICINLDITQRIEFENNLVDARLKAEQANSAKSLFL 881 DG IRYVQA A ++RD G+ +VI INLDIT++ + E L +A+ +A+ AN+AKS FL Sbjct: 845 TDGTIRYVQAAAQIERDVTGQVTKVIGINLDITEQRQLEETLREAKHEADAANAAKSAFL 904 Query: 882 ASVSHEIRTPMNGVLGMIQLLQRTQPLPAQQDYLDKAEISAKSLLNLLNDLLDFSKMDAK 941 A++SHEIRTPMN VLGM+QL+Q T QQDY+ K + +AKSLL LLND+LDFSK+DA Sbjct: 905 ANMSHEIRTPMNAVLGMLQLMQHTSMSVQQQDYVSKTQTAAKSLLGLLNDILDFSKIDAG 964 Query: 942 QLQLDPQAFELERFGHDLAAVLAGSPPQAGVRLHIALDPQLPRRLVGDAHRLQQVLVNLA 1001 +L LD +E DLA VL+G+ V + LDP LP L+ D RLQQ+LVNLA Sbjct: 965 KLTLDLHPCSIELLMRDLAIVLSGNHGNKNVEVMFDLDPALPAWLLADQLRLQQILVNLA 1024 Query: 1002 GNALKFTHQGHIDVHFTRLDPLPGRTVALRVEVSDTGIGIAADRLDDIFDAFTQAEASTT 1061 GNALKFT G + V L TV +++ +SDTGIGI+ ++++ IF F QAE+ST+ Sbjct: 1025 GNALKFTRHGQVTVAMECLRH-EVNTVTVQISISDTGIGISEEQIERIFTGFEQAESSTS 1083 Query: 1062 RRYGGTGLGLAISKHLVGLMGGQLQVSSEPGRGSRFWFDLQLAVDDDSVLGPAAADDAAR 1121 RR+GGTGLGLAISK LV LMGGQL V+S G GSRFWFD+ V + Sbjct: 1084 RRFGGTGLGLAISKKLVELMGGQLNVTSRVGVGSRFWFDVTFCVME-------------- 1129 Query: 1122 PQPLQAASHTAGSRAPETARAAPDAQCLQGVQILLVEDNPVNRQVASELLALSGAQVTCA 1181 A+H A L G IL+V+DNP+ ++ ++L G A Sbjct: 1130 ----VEATH---------------AIDLSGYHILIVDDNPLTVEILHKILTYFGCSAETA 1170 Query: 1182 DSGSMG---VAMACDPARHFDLVLMDLQMPGMDGIEATRRIRGQYELRGLPILAMTANAS 1238 G V A AR FD+VLMD +MP +DG++ I + +P++ M Sbjct: 1171 SGGYQALEKVKQANTNARPFDVVLMDWRMPDLDGLQTADLICNSHSDSPIPLIVMLTAYG 1230 Query: 1239 PE---DKQRCIEAGMAGHIAKPI 1258 E + Q + KP+ Sbjct: 1231 HEVISESQHIKNVPFVNFLTKPV 1253 Score = 156 bits (395), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 120/364 (32%), Positives = 178/364 (48%), Gaps = 28/364 (7%) Query: 1139 TARAAPDAQC-LQGVQILLVEDNPVNRQVASELLALSGAQVTCADSGSMGVAMACDPARH 1197 T P +Q L + IL+VEDN +NRQV ELL+ GA V A+ G GV + Sbjct: 1272 TVNPTPHSQRRLSTLAILVVEDNQLNRQVIDELLSYEGANVQLANGGVEGVFQVLESGNV 1331 Query: 1198 FDLVLMDLQMPGMDGIEATRRIRGQYELRGLPILAMTANASPEDKQRCIEAGMAGHIAKP 1257 FD+V+MD+QMP MDG+ ATR IR LPILAMTANAS DKQ C +AGM H+ KP Sbjct: 1332 FDIVIMDIQMPDMDGLAATRLIRADSRFAELPILAMTANASQSDKQDCFDAGMNDHVGKP 1391 Query: 1258 IDIATLIPVLLAHLHHERPVPEAASPPAPQDLA---EDRLCVEDYSSILHRFQQASDIYR 1314 ID+ L+P +L + E P A P +L +D ++D IL RF ++ Sbjct: 1392 IDMQILLPSILRLVGQEE-APSLAQQHQPAELQVPLDDMPLLDDIQLILRRFGGNQAFFQ 1450 Query: 1315 TTLDAAGPELERLLAQYCAALAMSPVRAQEAMAALAQASHALRGVTATIGARGLAAYFGA 1374 PE+ + L + + + A A H ++G+ + GA LAAY Sbjct: 1451 KMAKGFAPEMLKQLNLFKQSTKVFE------YATAAAVGHGIKGLASNFGALRLAAYAAF 1504 Query: 1375 LEQRCRQAMAGRTPDLDWLE-RCRTE-MDACQHDAMLVRQRLVMQALRPP----ASDAGP 1428 LE++ +Q DL+++E + TE ++ +++ Q+L +P A D Sbjct: 1505 LEKQLKQN------DLEFIEIKVWTEQLELLINEST---QQLSTYIPQPESTVLAQDKMT 1555 Query: 1429 AAAALATVAASDFPDRQRLRELLLSNNLEALDLIETLGKRHGLTQQEPYRQLNRLIEKLD 1488 A + S + + L LL +NNLEA+ ++ L K+ L + L ++ L+ Sbjct: 1556 QAIDSQALMPSAWTELNALMLLLKANNLEAMTFVDRLIKK--LPHHPQWITLQGQVQALE 1613 Query: 1489 FAAA 1492 F A Sbjct: 1614 FDKA 1617 >E0HVC3.1 E0HVC3_9GAMM Multi-sensor hybrid histidine kinase Length = 1629 Score = 641 bits (1653), Expect = 0.0, Method: Compositional matrix adjust. Identities = 454/1287 (35%), Positives = 664/1287 (51%), Gaps = 125/1287 (9%) Query: 29 LNERELHDSLAVDSRWIGDDIESLLRRYEHGLRGERGAILAIGEHALTRERMLRYMDSRD 88 +N + + +L ++ I +++ + + Y++GLRG RG+IL GE+ ++R RY SRD Sbjct: 35 MNAQTIGQALRENTEQISENVLNRITLYQYGLRGARGSILTAGEYGISRASFHRYSLSRD 94 Query: 89 LATEFPWAGGFGFIRHVPLSARAAYEQQVRQGRRLFPSITQLAENPGELYVIEYIEPIEA 148 + EFP A GFGFIR VP S AA+ + + +I QL + GE YVIEYIEPI+ Sbjct: 95 VDQEFPGARGFGFIRRVPNSDEAAFLTRAKNDDWPDFNIRQLTPHSGEKYVIEYIEPIDR 154 Query: 149 NRKALGLDIASSQARRSAADHAMLTGRAELTPPIHLVQKDGASANAYLFLLPIYAGSVTP 208 NR A+GLD+AS R++AAD AML+G L+ PI LVQ G ++L L PIY P Sbjct: 155 NRAAIGLDVASEAHRKAAADAAMLSGEVRLSAPITLVQATGKPLQSFLILQPIYRTISVP 214 Query: 209 PTLHERQEKIIGWAYAPLSVHDIISELSRRWKTHALEVLIKDAAADGDNVELFRSDGFDA 268 T ER GW+YAPL +++++ L+ K L L+ D + F + DA Sbjct: 215 KTPQERLAAGYGWSYAPLVTNEVLTGLALNQKMTKL--LLSDITQTERPISFFETHPDDA 272 Query: 269 LAQDSGLDSALS--LYGRTWKLQLRPSTDYRQT-HQFVSDRAMLLSCGSLLVLALVIALA 325 + S L+ ++GR W++++ + Q+ H +L L+LA IA+ Sbjct: 273 -SPLSAYSHTLTKEIFGRKWQVEVIAYPAFIQSLHLNQPSLVLLSGSLLSLLLAAFIAI- 330 Query: 326 YQTYSRREEKLQQAQALLAAVVDSSPDAIVTTDAQGRISSWNRGAADYLPSSPAQAL--- 382 + +R++++Q QA A++++ S DAI++ D G I+SWN+GA + + + Sbjct: 331 WSISLQRKQQVQLEQARRASMLEHSLDAIISYDLTGNITSWNQGAEEIFGYTQTDVIGHS 390 Query: 383 NTPLAQHPDLRDDLRARAASDASGQTTPHIVSL---QGAPVRYASAQVFALHDRAGRAVG 439 + L P + + + A SG+T + +S Q S ++D VG Sbjct: 391 SCDLIIPPSIVLEEQVLFAEVFSGKTVLNQISTHQRQNGSHVSTSTTSLPIYDEDSAIVG 450 Query: 440 KAFMLRDITHEKNIERQLQRINEELEWTVQQRTQALHQAKTMLQTVLNVMPSLVAYW--- 496 + +RDIT ++ ER + +N LE V +RT AL QA QT+L+ + + Y Sbjct: 451 LSQTIRDITTQQEAERYILSLNARLEQEVTKRTNALQQALLENQTLLDTINQQLLYSATD 510 Query: 497 -DRHLINHFANAAYERAFQREA--GQLNGVYMPDLVGPALFEKALPHIEGVLAGAQQTFE 553 + ++ N + + R+ G+ + + A + I+ L+ + Sbjct: 511 PNGVILEVNDNFCHVSGYSRKQLLGETHAILNSGEHDAAFWRTMWTQIKSGLSWHGEICN 570 Query: 554 RSVDDPVLGARHMLTTYI-----PEIGDLGEVTGFYVVAHDVTE---ITHNRNQLSETLA 605 R RH + + P + G + F + D+TE + +N+L Sbjct: 571 RD--------RHQMLKWFDTVIGPVFNENGNIERFVALRTDITERKLVQIEKNKLG---- 618 Query: 606 QNQSLLDQVQDANTLLNNVLSSAKGVAIIATDTEGLVTLFNSGAEQMLGYRAEDVVG--- 662 +LL NVL +A ++IIATD +G++T+FN GAEQ+LGY A D++G Sbjct: 619 -------------SLLTNVLDAASEMSIIATDKKGVITIFNRGAEQLLGYAAVDMIGLST 665 Query: 663 ----KLKEE------HFSSRPEAALPGQD----------SHTELL-YRRHDGATLPVARQ 701 L EE SS + G D S T Y R D + V+ Sbjct: 666 PAPLHLPEEVAARSAELSSEYGEDIQGFDVFVYKARTLGSETRTWTYVRKDTSQCQVSLS 725 Query: 702 QTSMFDHRQRHLGYLYIALDVSLQRQQASALAAARDQLVLAAEVAKLGVWVWDKDSDVLE 761 T+M D+ +GYL IA+D+S QQ AL A + L AAEVAKLG+W WD + LE Sbjct: 726 VTAMLDNVGEIIGYLGIAIDISQVLQQQKALITASNHLSKAAEVAKLGIWSWDLRDNSLE 785 Query: 762 YNPQVAEIY----GFGDRGGAPRVSTYADWRRRVHPDDVDYVEKTLRAGLAVDGDHEPVF 817 +N ++ IY D G TY WR R+H DD+D+ E L+A + ++P+F Sbjct: 786 WNERMFAIYDQPLSLQDIG-----LTYEHWRMRIHSDDIDFAEAKLKAAVEEKDQYDPIF 840 Query: 818 RVVRDDGGIRYVQARAYVQRDGAGRPVRVICINLDITQRIEFENNLVDARLKAEQANSAK 877 RVVR DG IRYVQA A ++RD G+ +VI INLDIT++ + E L +A+ +A+ AN+AK Sbjct: 841 RVVRTDGTIRYVQAGAQIERDVTGQVTKVIGINLDITEQRQLEETLREAKHEADAANAAK 900 Query: 878 SLFLASVSHEIRTPMNGVLGMIQLLQRTQPLPAQQDYLDKAEISAKSLLNLLNDLLDFSK 937 S FLA++SHEIRTPMN VLGM+QL+Q T QQDY+ K + +AKSLL LLND+LDFSK Sbjct: 901 SAFLANMSHEIRTPMNAVLGMLQLMQHTSMSVQQQDYVTKTQTAAKSLLGLLNDILDFSK 960 Query: 938 MDAKQLQLDPQAFELERFGHDLAAVLAGSPPQAGVRLHIALDPQLPRRLVGDAHRLQQVL 997 +DA +L LD +E DLA VL+G+ V + LDP LP L+ D RLQQ+L Sbjct: 961 IDAGKLTLDLHPCSIELLMRDLAIVLSGNHGNKNVEVMFDLDPALPAWLLADQLRLQQIL 1020 Query: 998 VNLAGNALKFTHQGHIDVHFTRLDPLPGRTVALRVEVSDTGIGIAADRLDDIFDAFTQAE 1057 VNLAGNALKFT G + V L TV +++ +SDTGIGI+ ++++ IF F QAE Sbjct: 1021 VNLAGNALKFTRHGQVTVTMECLRH-EANTVTVQISISDTGIGISEEQIERIFTGFEQAE 1079 Query: 1058 ASTTRRYGGTGLGLAISKHLVGLMGGQLQVSSEPGRGSRFWFDLQLAVDDDSVLGPAAAD 1117 +ST+RR+GGTGLGLAISK LV LMGGQL V+S G GSRFWFD+ V + Sbjct: 1080 SSTSRRFGGTGLGLAISKKLVELMGGQLNVTSRVGVGSRFWFDVTFCVME---------- 1129 Query: 1118 DAARPQPLQAASHTAGSRAPETARAAPDAQCLQGVQILLVEDNPVNRQVASELLALSGAQ 1177 A A L G IL+V+DN + ++ ++L G Sbjct: 1130 -----------------------VEATQAIDLSGYHILIVDDNELTVEILHKILTDFGCS 1166 Query: 1178 VTCADSGSMG---VAMACDPARHFDLVLMDLQMPGMDGIEATRRIRGQYELRGLPILAMT 1234 A G V A AR FD+VLMD +MP +DG++ I + +P++ M Sbjct: 1167 AETASGGYQALEKVKQANINARPFDVVLMDWRMPDLDGLQTADLICNSHSDSPIPLIVML 1226 Query: 1235 ANASPE---DKQRCIEAGMAGHIAKPI 1258 E + Q + KP+ Sbjct: 1227 TAYGHEVISESQHIKNVPFVNFLTKPV 1253 Score = 156 bits (394), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 120/364 (32%), Positives = 178/364 (48%), Gaps = 28/364 (7%) Query: 1139 TARAAPDAQC-LQGVQILLVEDNPVNRQVASELLALSGAQVTCADSGSMGVAMACDPARH 1197 T P +Q L + IL+VEDN +NRQV ELL+ GA V A+ G GV + Sbjct: 1272 TVNPTPHSQRRLSTLAILVVEDNQLNRQVIDELLSYEGANVQLANGGVEGVFQVLESGNV 1331 Query: 1198 FDLVLMDLQMPGMDGIEATRRIRGQYELRGLPILAMTANASPEDKQRCIEAGMAGHIAKP 1257 FD+V+MD+QMP MDG+ ATR IR LPILAMTANAS DKQ C +AGM H+ KP Sbjct: 1332 FDIVIMDIQMPDMDGLAATRLIRADSRFAELPILAMTANASQSDKQDCFDAGMNDHVGKP 1391 Query: 1258 IDIATLIPVLLAHLHHERPVPEAASPPAPQDLA---EDRLCVEDYSSILHRFQQASDIYR 1314 ID+ L+P +L + E P A P +L +D ++D IL RF ++ Sbjct: 1392 IDMQILLPSILRLVGQEE-APSLAQQHQPAELQVPLDDMPLLDDIQLILRRFGGNQAFFQ 1450 Query: 1315 TTLDAAGPELERLLAQYCAALAMSPVRAQEAMAALAQASHALRGVTATIGARGLAAYFGA 1374 PE+ + L + + + A A H ++G+ + GA LAAY Sbjct: 1451 KMAKGFAPEMLKQLNLFKQSTKVFE------YATAAAVGHGIKGLASNFGALRLAAYAAF 1504 Query: 1375 LEQRCRQAMAGRTPDLDWLE-RCRTE-MDACQHDAMLVRQRLVMQALRPP----ASDAGP 1428 LE++ +Q DL+++E + TE ++ +++ Q+L +P A D Sbjct: 1505 LEKQLKQN------DLEFIEIKVWTEQLELLINEST---QQLSTYIPQPESTVLAQDKMT 1555 Query: 1429 AAAALATVAASDFPDRQRLRELLLSNNLEALDLIETLGKRHGLTQQEPYRQLNRLIEKLD 1488 A + S + + L LL +NNLEA+ ++ L K+ L + L ++ L+ Sbjct: 1556 QAIDSQALMPSAWTELNALMLLLKANNLEAMTFVDRLIKK--LPHHPQWITLQGQVQALE 1613 Query: 1489 FAAA 1492 F A Sbjct: 1614 FDKA 1617 >B8ECP2.1 B8ECP2_SHEB2 Multi-sensor hybrid histidine kinase EC=2.7.13.3 Length = 1629 Score = 627 bits (1618), Expect = e-177, Method: Compositional matrix adjust. Identities = 454/1307 (34%), Positives = 684/1307 (52%), Gaps = 109/1307 (8%) Query: 29 LNERELHDSLAVDSRWIGDDIESLLRRYEHGLRGERGAILAIGEHALTRERMLRYMDSRD 88 +N + + +L ++ I +++ + + Y++GLRG RG I+ GEH ++R RY +RD Sbjct: 35 MNAQTIEQALRENAEQISENVINRITLYQYGLRGARGTIVTAGEHGISRASFHRYSLTRD 94 Query: 89 LATEFPWAGGFGFIRHVPLSARAAYEQQVRQGRRLFPSITQLAENPGELYVIEYIEPIEA 148 + EFP A GFGFIR VP + AA+ +VRQ +I QL + GE YVIEYIEP++ Sbjct: 95 VDHEFPGARGFGFIRRVPSADEAAFIARVRQDDWPDFNIRQLHAHDGERYVIEYIEPVDR 154 Query: 149 NRKALGLDIASSQARRSAADHAMLTGRAELTPPIHLVQKDGASANAYLFLLPIYAGSVTP 208 N+ A+GLDIAS R++AAD AML+G L+ PI LVQ G ++L L PIY + P Sbjct: 155 NKAAVGLDIASEAHRKAAADAAMLSGEVRLSAPITLVQATGRPLQSFLILQPIYRTGLVP 214 Query: 209 PTLHERQEKIIGWAYAPLSVHDIISELSRRWKTHALEVLIKDAAADGDNVELFRSDGFDA 268 T +R GW+YAPL ++++ L+ K L + D + F + D Sbjct: 215 KTQQDRLSAGYGWSYAPLVTNEVLMGLALNQKMTKL--FLSDITQAERPISFFETHP-DE 271 Query: 269 LAQDSGLDSALS--LYGRTWKLQLRPSTDYRQTHQFVSDRAMLLS-CGSLLVLALVIALA 325 + S ++ ++GR W++++ + ++ +LLS C L+LA +IA+ Sbjct: 272 ASPLSAYRHKMTKDIFGRQWQIEVIAYPSFIKSLHLNQPSLVLLSGCLFSLLLAALIAMW 331 Query: 326 YQTYSRREEKLQQAQALLAAVVDSSPDAIVTTDAQGRISSWNRGAADYLPSSPAQALN-- 383 + R+++ L + QA A++++ S D I++ D +G+I+SWN+GA + A AL Sbjct: 332 SISLQRKQQVLLE-QARRASMLEHSLDGIISYDTKGQITSWNQGAEQLFGYTEAHALGQS 390 Query: 384 -TPLAQHPDLRDDLRARAASDASGQTTPH-IVSLQGAPVRYASAQVFA--LHDRAGRAVG 439 L + + RA + +G+T+ + I S Q + S A ++D G+ G Sbjct: 391 CCKLIVPASIVQEERALFSEVLAGKTSLNRITSHQRQDGSHLSTSTTAVPIYDEHGKIAG 450 Query: 440 KAFMLRDITHEKNIERQLQRINEELEWTVQQRTQALHQAKTMLQTVLNVMPSLVAY--WD 497 + +RDIT + ER + +N LE V +RT AL QA QT+L+ + + Y D Sbjct: 451 MSQTIRDITAQLEAERHILSLNASLERQVTKRTHALQQALLENQTLLDTINQQLLYSVTD 510 Query: 498 RHLINHFANAAYERAFQREAGQLNGVYMPDLVG---PALFEKALPHIEGVLAGAQQTFER 554 + + N + R QL G L A F +A+ + + AG E Sbjct: 511 PNGVILEVNDNFCRISGYSREQLVGKTHAILKSGEHDASFWRAM--WQQINAGQSWHGEI 568 Query: 555 SVDDPVLGARHMLTTYIPEIGDLGEVTGFYVVAHDVTEITHNRNQLSETLAQNQSLLDQV 614 D + T P + G++ F + D+T+ L Q+ Sbjct: 569 CNLDKHQTLKWFDTVIGPVFDEYGKIERFVALRIDITD----------------RKLTQI 612 Query: 615 QDAN--TLLNNVLSSAKGVAIIATDTEGLVTLFNSGAEQMLGYRAEDVVGK--------L 664 + N +LL NVL +A ++IIATD +G +T+FN GAE++LGY AE+++G+ L Sbjct: 613 EKNNLGSLLTNVLDAASEMSIIATDVQGNITIFNRGAERLLGYSAEEMIGQSTPAPLHLL 672 Query: 665 KEEHFSSRPEAALPGQD---------------SHT-ELLYRRHDGATLPVARQQTSMFDH 708 +E S +A G+D S T Y R DG+ V+ T+M D Sbjct: 673 EEVMIRSAELSAEYGKDIQGFDVFIYKARAEGSETRNWTYVRKDGSQFQVSLSVTAMRDS 732 Query: 709 RQRHLGYLYIALDVSLQRQQASALAAARDQLVLAAEVAKLGVWVWDKDSDVLEYNPQVAE 768 +GYL I +D+SL Q AL A L AAEVA+LG+W W+ + LE+N ++ Sbjct: 733 VGEIIGYLGIGVDISLMLLQQQALMTASSHLSKAAEVAQLGIWTWNLLGNSLEWNERMFA 792 Query: 769 IYGFGDRGGAPRVS--TYADWRRRVHPDDVDYVEKTLRAGLAVDGDHEPVFRVVRDDGGI 826 IY D+ + R TY W RVHPDD+ + + L+ + ++P+FRVVR DG I Sbjct: 793 IY---DQPESLREQGLTYEHWSMRVHPDDIAFADAKLKGAVEGTAQYDPIFRVVRTDGSI 849 Query: 827 RYVQARAYVQRDGAGRPVRVICINLDITQRIEFENNLVDARLKAEQANSAKSLFLASVSH 886 RYVQA A ++RD G +RVI INLDIT++ + E L A+ +A+ A++AKS FLA++SH Sbjct: 850 RYVQAAAQIERDKQGNAIRVIGINLDITEQQQLEETLRKAKQEADAASAAKSAFLANMSH 909 Query: 887 EIRTPMNGVLGMIQLLQRTQPLPAQQDYLDKAEISAKSLLNLLNDLLDFSKMDAKQLQLD 946 EIRTPMN VLGM+QL+Q T QQDY++K + +AKSLL LLND+LDFSK+DA +L LD Sbjct: 910 EIRTPMNAVLGMLQLIQYTSLSRQQQDYVNKTQTAAKSLLGLLNDILDFSKIDAGKLALD 969 Query: 947 PQAFELERFGHDLAAVLAGSPPQAGVRLHIALDPQLPRRLVGDAHRLQQVLVNLAGNALK 1006 +E DLA VL+G+ V + LD LP L+ D RLQQ+LVNLAGNALK Sbjct: 970 LHPCSIELLMRDLAVVLSGNHGDKDVEVMFDLDTALPPWLLADQLRLQQILVNLAGNALK 1029 Query: 1007 FTHQGHIDVHFTRLDPLPGRTVALRVEVSDTGIGIAADRLDDIFDAFTQAEASTTRRYGG 1066 FTH G + V L TV +++ ++DTGIGI+ ++++ IF F QAE+ST+RR+GG Sbjct: 1030 FTHHGQVIVGIECLRH-EADTVTVQISITDTGIGISDEQIERIFTGFEQAESSTSRRFGG 1088 Query: 1067 TGLGLAISKHLVGLMGGQLQVSSEPGRGSRFWFDLQLAVDDDSVLGPAAADDAARPQPLQ 1126 TGLGLAISK L+GLMG +L V+S+ G GSRFWFD+ + ++ Sbjct: 1089 TGLGLAISKRLIGLMGSELHVTSKVGVGSRFWFDVTFPIIQ-----------------VE 1131 Query: 1127 AASHTAGSRAPETARAAPDAQCLQGVQILLVEDNPVNRQVASELLALSGAQVTCADSGSM 1186 HT L G ++L+V+DN + ++ ++L G +V A G Sbjct: 1132 ETRHTD----------------LSGYRVLVVDDNELTVEILEKILTGFGCEVETALGGYS 1175 Query: 1187 GVA---MACDPARHFDLVLMDLQMPGMDGIEATRRIRGQYELRGLPILAMTANASPE--- 1240 +A + + + FD+VLMD +MP +DG++ +R P++ M E Sbjct: 1176 ALAKVKQSHEKSTPFDVVLMDWRMPDLDGLQTAEMLRNSDANNQTPLVVMLTAYGHEVIA 1235 Query: 1241 DKQRCIEAGMAGHIAKPIDIATLIPVLLAHLHHERPVPEAASPPAPQ 1287 + Q+ + KP+ L +L + E EA P Q Sbjct: 1236 ESQQIRHVPFVNFLTKPVTSQILAEAVLNAI--EGKTMEAHPQPRSQ 1280 Score = 177 bits (449), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 120/352 (34%), Positives = 182/352 (51%), Gaps = 17/352 (4%) Query: 1149 LQGVQILLVEDNPVNRQVASELLALSGAQVTCADSGSMGVAMACDPARHFDLVLMDLQMP 1208 L G+ IL+VEDN +NRQV ELL+ GA V A+ G GV++ + FD+V+MD+QMP Sbjct: 1283 LAGLTILVVEDNQLNRQVIDELLSYEGANVVLAEGGMEGVSLVLESGDLFDIVIMDMQMP 1342 Query: 1209 GMDGIEATRRIRGQYELRGLPILAMTANASPEDKQRCIEAGMAGHIAKPIDIATLIPVLL 1268 MDG+EATRRIR LPILAMTANAS D+Q C+ AGM H+ KPID+ L+P +L Sbjct: 1343 DMDGLEATRRIRADGRFAALPILAMTANASQSDRQECLNAGMNDHVGKPIDMPLLLPSIL 1402 Query: 1269 AHLHHERPVP---EAASPPAPQDLAEDRLCVEDYSSILHRFQQASDIYRTTLDAAGPELE 1325 + E E P A Q+ ++++L ++D IL RF ++ + PE+ Sbjct: 1403 RLVGREDMTSAEFEGHWPEATQEQSDEQL-LDDIRLILRRFGGNQSFFQKMAKSFAPEMM 1461 Query: 1326 RLLAQYCAALAMSPVRAQEAMAALAQASHALRGVTATIGARGLAAYFGALEQRCRQAMAG 1385 + LA + + + + AA+ SH ++G+ + GAR LAA+ LE++ +Q Sbjct: 1462 KQLALFKQS---TKIFDHSTAAAI---SHGIKGIASNFGARRLAAHAAYLEKQFKQ---- 1511 Query: 1386 RTPDLDWLERCRTEMDA-CQHDAMLVRQRLVMQALRPPASDAGPAAAALATVAASDFPDR 1444 P+L ++R ++ + + ++ SD A + S D Sbjct: 1512 ECPELIDIKRWTDTLEELINQSSQQLSTYFEVEEFNAVISDNVEKAVYSSVSVQSVKTDL 1571 Query: 1445 QRLRELLLSNNLEALDLIETLGKRHGLTQQEPYRQLNRLIEKLDFAAALTCL 1496 L LL NNLEA+ L + L + L+ + L+ ++ LDF AL L Sbjct: 1572 NTLMTLLKENNLEAMALTDQLAEL--LSGHPQWSILHGQVQALDFNQALDTL 1621 >E0IR00.1 E0IR00_9GAMM Multi-sensor hybrid histidine kinase Length = 1629 Score = 618 bits (1593), Expect = e-174, Method: Compositional matrix adjust. Identities = 451/1308 (34%), Positives = 685/1308 (52%), Gaps = 111/1308 (8%) Query: 29 LNERELHDSLAVDSRWIGDDIESLLRRYEHGLRGERGAILAIGEHALTRERMLRYMDSRD 88 +N +++ +L D+ I +++ + + Y++GLRG RG I+ GEH ++R RY +RD Sbjct: 35 MNAQKIEQALREDAEQISENVINRITLYQYGLRGARGTIVTAGEHDISRASFHRYSLTRD 94 Query: 89 LATEFPWAGGFGFIRHVPLSARAAYEQQVRQGRRLFPSITQLAENPGELYVIEYIEPIEA 148 + EFP A GFGFIR VP + AA+ + RQ +I QL + GE YVIEYIEP++ Sbjct: 95 VDHEFPGARGFGFIRRVPSADEAAFIARARQDDWPDFNIRQLNAHDGERYVIEYIEPVDR 154 Query: 149 NRKALGLDIASSQARRSAADHAMLTGRAELTPPIHLVQKDGASANAYLFLLPIYAGSVTP 208 N+ A+GLDIAS R++AAD AML+G L+ PI LVQ G ++L L PIY + P Sbjct: 155 NKAAVGLDIASEAHRKAAADAAMLSGEVRLSAPITLVQATGRPLQSFLILQPIYRTGLVP 214 Query: 209 PTLHERQEKIIGWAYAPLSVHDIISELSRRWKTHALEVLIKDAAADGDNVELFRSDGFDA 268 + +R GW+YAPL ++++ L+ K L L+ D + F + D Sbjct: 215 KSQQDRLSAGYGWSYAPLVTNEVLMGLALNQKMTKL--LLSDITQAERPISFFETHP-DE 271 Query: 269 LAQDSGLDSALS--LYGRTWKLQLRPSTDY-RQTHQFVSDRAMLLSCGSLLVLALVIALA 325 + S ++ ++GR W++++ + + H +L L+LA +IA+ Sbjct: 272 ASPLSAYRHKMTKDIFGRQWQIEVIAYPSFIKSLHLNQPSLVLLSGSLFSLLLAALIAMW 331 Query: 326 YQTYSRREEKLQQAQALLAAVVDSSPDAIVTTDAQGRISSWNRGAADYLPSSPAQALN-- 383 + R+++ L + QA A++++ S D I++ D +G+I+SWN+GA + A AL Sbjct: 332 SISLQRKQQVLLE-QARRASMLEHSLDGIISYDTKGQITSWNQGAEQLFGYTEAHALGQS 390 Query: 384 -TPLAQHPDLRDDLRARAASDASGQTTPH-IVSLQGAPVRYASAQVFA--LHDRAGRAVG 439 L + + RA A +G+T+ + I S Q + S A ++D G+ G Sbjct: 391 CCKLIVPASIVQEERALFAEVLAGKTSLNRITSHQRQDGSHLSTSTTAVPIYDEHGKIAG 450 Query: 440 KAFMLRDITHEKNIERQLQRINEELEWTVQQRTQALHQAKTMLQTVLNVMPSLVAY--WD 497 + +RDIT + ER + +N LE V +RT AL QA QT+L+ + + Y D Sbjct: 451 MSQTIRDITAQLEAERHILSLNASLERQVTKRTHALQQALLENQTLLDTINQQLLYSVTD 510 Query: 498 RHLINHFANAAYER--AFQRE--AGQLNGVYMPDLVGPALFEKALPHIEGVLAGAQQTFE 553 + + N + R + RE G+ + + + + I +G E Sbjct: 511 PNGVILEVNDNFCRISGYSREQLVGKTHAILQSGEHDVSFWRSMWQQIN---SGQSWHGE 567 Query: 554 RSVDDPVLGARHMLTTYIPEIGDLGEVTGFYVVAHDVTEITHNRNQLSETLAQNQSLLDQ 613 D + T P + G++ F + D+T+ L Q Sbjct: 568 ICNLDKHQTLKWFDTVIGPVFDEYGKIERFVALRIDITD----------------RKLTQ 611 Query: 614 VQDAN--TLLNNVLSSAKGVAIIATDTEGLVTLFNSGAEQMLGYRAEDVVGK-------- 663 ++ N +LL NVL +A ++IIATD +G +T+FN GAE++LGY AE+++G+ Sbjct: 612 IEKNNLGSLLTNVLDAASEMSIIATDVQGNITIFNRGAERLLGYSAEEMIGQSTPAPLHL 671 Query: 664 LKEEHFSSRPEAALPGQD---------------SHT-ELLYRRHDGATLPVARQQTSMFD 707 L+E S +A G+D S T Y R DG+ V+ T+M D Sbjct: 672 LEEVMIRSAELSAEYGKDIQGFDVFVYKAKAEGSETRNWTYVRKDGSQFQVSLSVTAMRD 731 Query: 708 HRQRHLGYLYIALDVSLQRQQASALAAARDQLVLAAEVAKLGVWVWDKDSDVLEYNPQVA 767 +GYL I +D+SL Q AL A + L AAEVA+LG+W W+ + LE+N ++ Sbjct: 732 SVGEIIGYLGIGVDISLMLLQQQALMTASNHLSKAAEVAQLGIWTWNLLGNSLEWNERMF 791 Query: 768 EIYGFGDRGGAPRVS--TYADWRRRVHPDDVDYVEKTLRAGLAVDGDHEPVFRVVRDDGG 825 IY D+ + R TY W RVHPDD+ + + L+ + ++P+FRVVR DG Sbjct: 792 AIY---DQPESLREQGLTYEHWSMRVHPDDIAFADAKLKGAVEGTAQYDPIFRVVRTDGS 848 Query: 826 IRYVQARAYVQRDGAGRPVRVICINLDITQRIEFENNLVDARLKAEQANSAKSLFLASVS 885 IRYVQA A V+RD G +RVI INLDIT++ + E +L +A+ +A+ A++AKS FLA++S Sbjct: 849 IRYVQAAAQVERDKQGHAIRVIGINLDITEQQQLEESLREAKQEADAASAAKSAFLANMS 908 Query: 886 HEIRTPMNGVLGMIQLLQRTQPLPAQQDYLDKAEISAKSLLNLLNDLLDFSKMDAKQLQL 945 HEIRTPMN VLGM+QL+Q T QQDY++K + +AKSLL LLND+LDFSK+DA +L L Sbjct: 909 HEIRTPMNAVLGMLQLIQYTSLSRQQQDYVNKTQTAAKSLLGLLNDILDFSKIDAGKLVL 968 Query: 946 DPQAFELERFGHDLAAVLAGSPPQAGVRLHIALDPQLPRRLVGDAHRLQQVLVNLAGNAL 1005 D +E DLA VL+G+ V + LD LP L+ D RLQQ+LVNLAGNAL Sbjct: 969 DLHPCSIELLMRDLAVVLSGNHGDKDVEVMFDLDTALPPWLLADQLRLQQILVNLAGNAL 1028 Query: 1006 KFTHQGHIDVHFTRLDPLPGRTVALRVEVSDTGIGIAADRLDDIFDAFTQAEASTTRRYG 1065 KFTH G + V L TV +++ ++DTGIGI+ ++++ IF F QAE+ST+RR+G Sbjct: 1029 KFTHHGQVIVGIECLRH-EADTVTVQISITDTGIGISDEQIERIFTGFEQAESSTSRRFG 1087 Query: 1066 GTGLGLAISKHLVGLMGGQLQVSSEPGRGSRFWFDLQLAVDDDSVLGPAAADDAARPQPL 1125 GTGLGLAISK L+GLMG +LQV+S+ G GSRFWFD+ + + Sbjct: 1088 GTGLGLAISKRLIGLMGSELQVTSKVGVGSRFWFDMTFPIIQ-----------------V 1130 Query: 1126 QAASHTAGSRAPETARAAPDAQCLQGVQILLVEDNPVNRQVASELLALSGAQVTCADSGS 1185 + HT L G ++L+V+DN + ++ ++L G +V A G Sbjct: 1131 EETRHTD----------------LSGYRVLVVDDNELTVEILEKILTGFGCEVETALGGY 1174 Query: 1186 MGVA---MACDPARHFDLVLMDLQMPGMDGIEATRRIRGQYELRGLPILAMTANASPE-- 1240 +A + + + FD+VLMD +MP +DG++ +R P++ M E Sbjct: 1175 SALAKVKQSHEKSTPFDVVLMDWRMPDLDGLQTAEMLRNSDANNQTPLVVMLTAYGHEVI 1234 Query: 1241 -DKQRCIEAGMAGHIAKPIDIATLIPVLLAHLHHERPVPEAASPPAPQ 1287 + Q+ + KP+ L +L + E EA P Q Sbjct: 1235 AESQQIRHVPFVNFLTKPVTSQILAEAVLNAI--EGKTMEAHPQPRSQ 1280 Score = 178 bits (451), Expect = 8e-42, Method: Compositional matrix adjust. Identities = 120/352 (34%), Positives = 182/352 (51%), Gaps = 17/352 (4%) Query: 1149 LQGVQILLVEDNPVNRQVASELLALSGAQVTCADSGSMGVAMACDPARHFDLVLMDLQMP 1208 L G+ IL+VEDN +NRQV ELL+ GA V A+ G GV++ + FD+V+MD+QMP Sbjct: 1283 LAGLTILVVEDNQLNRQVIDELLSYEGANVVLAEGGMEGVSLVLESGDLFDIVIMDMQMP 1342 Query: 1209 GMDGIEATRRIRGQYELRGLPILAMTANASPEDKQRCIEAGMAGHIAKPIDIATLIPVLL 1268 MDG+EATRRIR LPILAMTANAS D+Q C+ AGM H+ KPID+ L+P +L Sbjct: 1343 DMDGLEATRRIRADERFAALPILAMTANASQSDRQECLNAGMNDHVGKPIDMPLLLPSIL 1402 Query: 1269 AHLHHERPVP---EAASPPAPQDLAEDRLCVEDYSSILHRFQQASDIYRTTLDAAGPELE 1325 + E E P A Q+ ++++L ++D IL RF ++ + PE+ Sbjct: 1403 RLVGREDMTSAEFEGHWPEATQEQSDEQL-LDDIRLILRRFGGNQSFFQKMAKSFAPEMM 1461 Query: 1326 RLLAQYCAALAMSPVRAQEAMAALAQASHALRGVTATIGARGLAAYFGALEQRCRQAMAG 1385 + LA + + + + AA+ SH ++G+ + GAR LAA+ LE++ +Q Sbjct: 1462 KQLALFKQS---TKIFDHSTAAAI---SHGIKGIASNFGARRLAAHAAYLEKQFKQ---- 1511 Query: 1386 RTPDLDWLERCRTEMDA-CQHDAMLVRQRLVMQALRPPASDAGPAAAALATVAASDFPDR 1444 P+L ++R ++ + + ++ SD A + S D Sbjct: 1512 ECPELIDIKRWTDTLEELINQSSQQLSTYFEVEEFNAVISDNVEKAVYSSVSVQSVKTDL 1571 Query: 1445 QRLRELLLSNNLEALDLIETLGKRHGLTQQEPYRQLNRLIEKLDFAAALTCL 1496 L LL NNLEA+ L + L + L+ + L+ ++ LDF AL L Sbjct: 1572 NTLMNLLKENNLEAMALTDQLAEL--LSGHPQWSILHGQVQALDFNQALDTL 1621 >E0HT85.1 E0HT85_9GAMM Multi-sensor hybrid histidine kinase Length = 1629 Score = 618 bits (1593), Expect = e-174, Method: Compositional matrix adjust. Identities = 451/1308 (34%), Positives = 685/1308 (52%), Gaps = 111/1308 (8%) Query: 29 LNERELHDSLAVDSRWIGDDIESLLRRYEHGLRGERGAILAIGEHALTRERMLRYMDSRD 88 +N +++ +L D+ I +++ + + Y++GLRG RG I+ GEH ++R RY +RD Sbjct: 35 MNAQKIEQALREDAEQISENVINRITLYQYGLRGARGTIVTAGEHDISRASFHRYSLTRD 94 Query: 89 LATEFPWAGGFGFIRHVPLSARAAYEQQVRQGRRLFPSITQLAENPGELYVIEYIEPIEA 148 + EFP A GFGFIR VP + AA+ + RQ +I QL + GE YVIEYIEP++ Sbjct: 95 VDHEFPGARGFGFIRRVPSADEAAFIARARQDDWPDFNIRQLNAHDGERYVIEYIEPVDR 154 Query: 149 NRKALGLDIASSQARRSAADHAMLTGRAELTPPIHLVQKDGASANAYLFLLPIYAGSVTP 208 N+ A+GLDIAS R++AAD AML+G L+ PI LVQ G ++L L PIY + P Sbjct: 155 NKAAVGLDIASEAHRKAAADAAMLSGEVRLSAPITLVQATGRPLQSFLILQPIYRTGLVP 214 Query: 209 PTLHERQEKIIGWAYAPLSVHDIISELSRRWKTHALEVLIKDAAADGDNVELFRSDGFDA 268 + +R GW+YAPL ++++ L+ K L L+ D + F + D Sbjct: 215 KSQQDRLSAGYGWSYAPLVTNEVLMGLALNQKMTKL--LLSDITQAERPISFFETHP-DE 271 Query: 269 LAQDSGLDSALS--LYGRTWKLQLRPSTDY-RQTHQFVSDRAMLLSCGSLLVLALVIALA 325 + S ++ ++GR W++++ + + H +L L+LA +IA+ Sbjct: 272 ASPLSAYRHKMTKDIFGRQWQIEVIAYPSFIKSLHLNQPSLVLLSGSLFSLLLAALIAMW 331 Query: 326 YQTYSRREEKLQQAQALLAAVVDSSPDAIVTTDAQGRISSWNRGAADYLPSSPAQALN-- 383 + R+++ L + QA A++++ S D I++ D +G+I+SWN+GA + A AL Sbjct: 332 SISLQRKQQVLLE-QARRASMLEHSLDGIISYDTKGQITSWNQGAEQLFGYTEAHALGQS 390 Query: 384 -TPLAQHPDLRDDLRARAASDASGQTTPH-IVSLQGAPVRYASAQVFA--LHDRAGRAVG 439 L + + RA A +G+T+ + I S Q + S A ++D G+ G Sbjct: 391 CCKLIVPASIVQEERALFAEVLAGKTSLNRITSHQRQDGSHLSTSTTAVPIYDEHGKIAG 450 Query: 440 KAFMLRDITHEKNIERQLQRINEELEWTVQQRTQALHQAKTMLQTVLNVMPSLVAY--WD 497 + +RDIT + ER + +N LE V +RT AL QA QT+L+ + + Y D Sbjct: 451 MSQTIRDITAQLEAERHILSLNASLERQVTKRTHALQQALLENQTLLDTINQQLLYSVTD 510 Query: 498 RHLINHFANAAYER--AFQRE--AGQLNGVYMPDLVGPALFEKALPHIEGVLAGAQQTFE 553 + + N + R + RE G+ + + + + I +G E Sbjct: 511 PNGVILEVNDNFCRISGYSREQLVGKTHAILQSGEHDVSFWRSMWQQIN---SGQSWHGE 567 Query: 554 RSVDDPVLGARHMLTTYIPEIGDLGEVTGFYVVAHDVTEITHNRNQLSETLAQNQSLLDQ 613 D + T P + G++ F + D+T+ L Q Sbjct: 568 ICNLDKHQTLKWFDTVIGPVFDEYGKIERFVALRIDITD----------------RKLTQ 611 Query: 614 VQDAN--TLLNNVLSSAKGVAIIATDTEGLVTLFNSGAEQMLGYRAEDVVGK-------- 663 ++ N +LL NVL +A ++IIATD +G +T+FN GAE++LGY AE+++G+ Sbjct: 612 IEKNNLGSLLTNVLDAASEMSIIATDVQGNITIFNRGAERLLGYSAEEMIGQSTPAPLHL 671 Query: 664 LKEEHFSSRPEAALPGQD---------------SHT-ELLYRRHDGATLPVARQQTSMFD 707 L+E S +A G+D S T Y R DG+ V+ T+M D Sbjct: 672 LEEVMIRSAELSAEYGKDIQGFDVFVYKAKAEGSETRNWTYVRKDGSQFQVSLSVTAMRD 731 Query: 708 HRQRHLGYLYIALDVSLQRQQASALAAARDQLVLAAEVAKLGVWVWDKDSDVLEYNPQVA 767 +GYL I +D+SL Q AL A + L AAEVA+LG+W W+ + LE+N ++ Sbjct: 732 SVGEIIGYLGIGVDISLMLLQQQALMTASNHLSKAAEVAQLGIWTWNLLGNSLEWNERMF 791 Query: 768 EIYGFGDRGGAPRVS--TYADWRRRVHPDDVDYVEKTLRAGLAVDGDHEPVFRVVRDDGG 825 IY D+ + R TY W RVHPDD+ + + L+ + ++P+FRVVR DG Sbjct: 792 AIY---DQPESLREQGLTYEHWSMRVHPDDIAFADAKLKGAVEGTAQYDPIFRVVRTDGS 848 Query: 826 IRYVQARAYVQRDGAGRPVRVICINLDITQRIEFENNLVDARLKAEQANSAKSLFLASVS 885 IRYVQA A V+RD G +RVI INLDIT++ + E +L +A+ +A+ A++AKS FLA++S Sbjct: 849 IRYVQAAAQVERDKQGHAIRVIGINLDITEQQQLEESLREAKQEADAASAAKSAFLANMS 908 Query: 886 HEIRTPMNGVLGMIQLLQRTQPLPAQQDYLDKAEISAKSLLNLLNDLLDFSKMDAKQLQL 945 HEIRTPMN VLGM+QL+Q T QQDY++K + +AKSLL LLND+LDFSK+DA +L L Sbjct: 909 HEIRTPMNAVLGMLQLIQYTSLSRQQQDYVNKTQTAAKSLLGLLNDILDFSKIDAGKLVL 968 Query: 946 DPQAFELERFGHDLAAVLAGSPPQAGVRLHIALDPQLPRRLVGDAHRLQQVLVNLAGNAL 1005 D +E DLA VL+G+ V + LD LP L+ D RLQQ+LVNLAGNAL Sbjct: 969 DLHPCSIELLMRDLAVVLSGNHGDKDVEVMFDLDTALPPWLLADQLRLQQILVNLAGNAL 1028 Query: 1006 KFTHQGHIDVHFTRLDPLPGRTVALRVEVSDTGIGIAADRLDDIFDAFTQAEASTTRRYG 1065 KFTH G + V L TV +++ ++DTGIGI+ ++++ IF F QAE+ST+RR+G Sbjct: 1029 KFTHHGQVIVGIECLRH-EADTVTVQISITDTGIGISDEQIERIFTGFEQAESSTSRRFG 1087 Query: 1066 GTGLGLAISKHLVGLMGGQLQVSSEPGRGSRFWFDLQLAVDDDSVLGPAAADDAARPQPL 1125 GTGLGLAISK L+GLMG +LQV+S+ G GSRFWFD+ + + Sbjct: 1088 GTGLGLAISKRLIGLMGSELQVTSKVGVGSRFWFDMTFPIIQ-----------------V 1130 Query: 1126 QAASHTAGSRAPETARAAPDAQCLQGVQILLVEDNPVNRQVASELLALSGAQVTCADSGS 1185 + HT L G ++L+V+DN + ++ ++L G +V A G Sbjct: 1131 EETRHTD----------------LSGYRVLVVDDNELTVEILEKILTGFGCEVETALGGY 1174 Query: 1186 MGVA---MACDPARHFDLVLMDLQMPGMDGIEATRRIRGQYELRGLPILAMTANASPE-- 1240 +A + + + FD+VLMD +MP +DG++ +R P++ M E Sbjct: 1175 SALAKVKQSHEKSTPFDVVLMDWRMPDLDGLQTAEMLRNSDANNQTPLVVMLTAYGHEVI 1234 Query: 1241 -DKQRCIEAGMAGHIAKPIDIATLIPVLLAHLHHERPVPEAASPPAPQ 1287 + Q+ + KP+ L +L + E EA P Q Sbjct: 1235 AESQQIRHVPFVNFLTKPVTSQILAEAVLNAI--EGKTMEAHPQPRSQ 1280 Score = 178 bits (451), Expect = 8e-42, Method: Compositional matrix adjust. Identities = 120/352 (34%), Positives = 182/352 (51%), Gaps = 17/352 (4%) Query: 1149 LQGVQILLVEDNPVNRQVASELLALSGAQVTCADSGSMGVAMACDPARHFDLVLMDLQMP 1208 L G+ IL+VEDN +NRQV ELL+ GA V A+ G GV++ + FD+V+MD+QMP Sbjct: 1283 LAGLTILVVEDNQLNRQVIDELLSYEGANVVLAEGGMEGVSLVLESGDLFDIVIMDMQMP 1342 Query: 1209 GMDGIEATRRIRGQYELRGLPILAMTANASPEDKQRCIEAGMAGHIAKPIDIATLIPVLL 1268 MDG+EATRRIR LPILAMTANAS D+Q C+ AGM H+ KPID+ L+P +L Sbjct: 1343 DMDGLEATRRIRADERFAALPILAMTANASQSDRQECLNAGMNDHVGKPIDMPLLLPSIL 1402 Query: 1269 AHLHHERPVP---EAASPPAPQDLAEDRLCVEDYSSILHRFQQASDIYRTTLDAAGPELE 1325 + E E P A Q+ ++++L ++D IL RF ++ + PE+ Sbjct: 1403 RLVGREDMTSAEFEGHWPEATQEQSDEQL-LDDIRLILRRFGGNQSFFQKMAKSFAPEMM 1461 Query: 1326 RLLAQYCAALAMSPVRAQEAMAALAQASHALRGVTATIGARGLAAYFGALEQRCRQAMAG 1385 + LA + + + + AA+ SH ++G+ + GAR LAA+ LE++ +Q Sbjct: 1462 KQLALFKQS---TKIFDHSTAAAI---SHGIKGIASNFGARRLAAHAAYLEKQFKQ---- 1511 Query: 1386 RTPDLDWLERCRTEMDA-CQHDAMLVRQRLVMQALRPPASDAGPAAAALATVAASDFPDR 1444 P+L ++R ++ + + ++ SD A + S D Sbjct: 1512 ECPELIDIKRWTDTLEELINQSSQQLSTYFEVEEFNAVISDNVEKAVYSSVSVQSVKTDL 1571 Query: 1445 QRLRELLLSNNLEALDLIETLGKRHGLTQQEPYRQLNRLIEKLDFAAALTCL 1496 L LL NNLEA+ L + L + L+ + L+ ++ LDF AL L Sbjct: 1572 NTLMNLLKENNLEAMALTDQLAEL--LSGHPQWSILHGQVQALDFNQALDTL 1621 >E6T8U9.1 E6T8U9_SHEB6 Multi-sensor hybrid histidine kinase Length = 1629 Score = 616 bits (1588), Expect = e-173, Method: Compositional matrix adjust. Identities = 450/1308 (34%), Positives = 683/1308 (52%), Gaps = 111/1308 (8%) Query: 29 LNERELHDSLAVDSRWIGDDIESLLRRYEHGLRGERGAILAIGEHALTRERMLRYMDSRD 88 +N +++ +L D+ I +++ + + Y++GLRG RG I+ GEH ++R RY +RD Sbjct: 35 MNAQKIEQALREDAEQISENVINRITLYQYGLRGARGTIVTAGEHDISRASFHRYSLTRD 94 Query: 89 LATEFPWAGGFGFIRHVPLSARAAYEQQVRQGRRLFPSITQLAENPGELYVIEYIEPIEA 148 + EFP A GFGFIR VP AA+ + RQ +I QL + GE YVIEYIEP++ Sbjct: 95 VDHEFPGARGFGFIRRVPSPDEAAFIARARQDDWPDFNIRQLNAHDGERYVIEYIEPVDR 154 Query: 149 NRKALGLDIASSQARRSAADHAMLTGRAELTPPIHLVQKDGASANAYLFLLPIYAGSVTP 208 N+ A+GLDIAS R++AAD AML+G L+ PI LVQ G ++L L PIY + P Sbjct: 155 NKAAVGLDIASEAHRKAAADAAMLSGEVRLSAPITLVQATGRPLQSFLILQPIYRTGLVP 214 Query: 209 PTLHERQEKIIGWAYAPLSVHDIISELSRRWKTHALEVLIKDAAADGDNVELFRSDGFDA 268 T +R GW+YAPL ++++ L+ K L L+ D + F + D Sbjct: 215 KTQQDRLSAGYGWSYAPLVTNEVLMGLALNQKMTKL--LLSDITQAERPISFFETHP-DE 271 Query: 269 LAQDSGLDSALS--LYGRTWKLQLRPSTDY-RQTHQFVSDRAMLLSCGSLLVLALVIALA 325 + S ++ ++GR W++++ + + H +L L+LA +IA+ Sbjct: 272 ASPLSAYRHKMTKDIFGRKWQIEVIAYPSFIKSLHLNQPSLVLLSGSLFSLLLAALIAMW 331 Query: 326 YQTYSRREEKLQQAQALLAAVVDSSPDAIVTTDAQGRISSWNRGAADYLPSSPAQALN-- 383 + R+++ L + QA A++++ S D I++ D +G+I+SWN+GA + A AL Sbjct: 332 SISLQRKQQVLLE-QARRASMLEHSLDGIISYDTKGQITSWNQGAEQLFGYTEAHALGQS 390 Query: 384 -TPLAQHPDLRDDLRARAASDASGQTTPH-IVSLQGAPVRYASAQVFA--LHDRAGRAVG 439 L + + RA A +G+T+ + I S Q + S A ++D G+ G Sbjct: 391 CCKLIVPASIVQEERALFAEVLAGKTSLNRITSHQRQDGSHLSTSTTAVPIYDEHGKIAG 450 Query: 440 KAFMLRDITHEKNIERQLQRINEELEWTVQQRTQALHQAKTMLQTVLNVMPSLVAY--WD 497 + +RDIT + ER + +N LE V +RT AL QA QT+L+ + + Y D Sbjct: 451 MSQTIRDITAQLEAERHILSLNASLERQVTKRTHALQQALLENQTLLDTINQQLLYSVTD 510 Query: 498 RHLINHFANAAYER--AFQRE--AGQLNGVYMPDLVGPALFEKALPHIEGVLAGAQQTFE 553 + + N + R + RE G+ + + + ++ I AG E Sbjct: 511 PNGVILEVNDNFCRISGYPREQLVGKTHAILQSGEHDASFWQSMWQQIN---AGQSWHGE 567 Query: 554 RSVDDPVLGARHMLTTYIPEIGDLGEVTGFYVVAHDVTEITHNRNQLSETLAQNQSLLDQ 613 D + T P + G++ F + D+T+ L Q Sbjct: 568 ICNLDKHQTLKWFDTVIGPVFDEYGKIERFVALRIDITD----------------RKLTQ 611 Query: 614 VQDAN--TLLNNVLSSAKGVAIIATDTEGLVTLFNSGAEQMLGYRAEDVVGK-------- 663 ++ N +LL NVL +A ++IIATD +G +T+FN GAE++LGY AE+++G+ Sbjct: 612 IEKNNLGSLLTNVLDAASEMSIIATDVQGNITIFNRGAERLLGYSAEEMIGQSTPAPLHL 671 Query: 664 LKEEHFSSRPEAALPGQD---------------SHT-ELLYRRHDGATLPVARQQTSMFD 707 L+E S +A G+D S T Y R DG+ V+ T+M D Sbjct: 672 LEEVMIRSAELSAEYGKDIQGFDVFIYKARAEGSETRNWTYVRKDGSQFQVSLSVTAMRD 731 Query: 708 HRQRHLGYLYIALDVSLQRQQASALAAARDQLVLAAEVAKLGVWVWDKDSDVLEYNPQVA 767 +GYL I +D+SL Q AL A + L AAEVA+LG+W W+ + LE+N ++ Sbjct: 732 SVGEIIGYLGIGVDISLMLLQQQALMTASNHLSKAAEVAQLGIWTWNLLGNSLEWNERMF 791 Query: 768 EIYGFGDRGGAPRVS--TYADWRRRVHPDDVDYVEKTLRAGLAVDGDHEPVFRVVRDDGG 825 IY D+ + R TY W RVHPDD+ + + L+ + ++P+FRVVR DG Sbjct: 792 AIY---DQPESLREQGLTYEHWSMRVHPDDIAFADAKLKGAVEGTAKYDPIFRVVRTDGS 848 Query: 826 IRYVQARAYVQRDGAGRPVRVICINLDITQRIEFENNLVDARLKAEQANSAKSLFLASVS 885 IR+VQA A V+RD G +RVI INLDIT++ + E +L +A+ +A+ A++AKS FLA++S Sbjct: 849 IRFVQAAAQVERDKQGHAIRVIGINLDITEQQQLEESLREAKQEADAASAAKSAFLANMS 908 Query: 886 HEIRTPMNGVLGMIQLLQRTQPLPAQQDYLDKAEISAKSLLNLLNDLLDFSKMDAKQLQL 945 HEIRTPMN VLGM+QL+Q T QQDY++K + +AKSLL LLND+LDFSK+D +L L Sbjct: 909 HEIRTPMNAVLGMLQLIQYTSLSRQQQDYVNKTQTAAKSLLGLLNDILDFSKIDVGKLIL 968 Query: 946 DPQAFELERFGHDLAAVLAGSPPQAGVRLHIALDPQLPRRLVGDAHRLQQVLVNLAGNAL 1005 D +E DLA VL+G+ V + LD LP L+ D RLQQ+LVNLAGNAL Sbjct: 969 DLHPCSIELLMRDLAVVLSGNHGDKDVEVMFDLDTALPPWLLADQLRLQQILVNLAGNAL 1028 Query: 1006 KFTHQGHIDVHFTRLDPLPGRTVALRVEVSDTGIGIAADRLDDIFDAFTQAEASTTRRYG 1065 KFTH G + V L TV +++ ++DTGIGI+ ++++ IF F QAE+ST+RR+G Sbjct: 1029 KFTHHGQVIVGIECLRH-EADTVTVQISITDTGIGISDEQIERIFTGFEQAESSTSRRFG 1087 Query: 1066 GTGLGLAISKHLVGLMGGQLQVSSEPGRGSRFWFDLQLAVDDDSVLGPAAADDAARPQPL 1125 GTGLGLAISK L+GLMG +L V+S+ G GSRFWFD+ + + Sbjct: 1088 GTGLGLAISKRLIGLMGSELHVTSKVGVGSRFWFDMTFPIIQ-----------------V 1130 Query: 1126 QAASHTAGSRAPETARAAPDAQCLQGVQILLVEDNPVNRQVASELLALSGAQVTCADSGS 1185 + HT L G ++L+V+DN + ++ ++L G +V A G Sbjct: 1131 EETRHTD----------------LSGYRVLVVDDNELTTEILEKILTGFGCEVETALGGY 1174 Query: 1186 MGVA---MACDPARHFDLVLMDLQMPGMDGIEATRRIRGQYELRGLPILAMTANASPE-- 1240 +A + + + FD+VLMD +MP +DG++ +R P++ M E Sbjct: 1175 AALAKVKQSHEKSTPFDVVLMDWRMPDLDGLQTAEMLRNSDANNQTPLVVMLTAYGHEVI 1234 Query: 1241 -DKQRCIEAGMAGHIAKPIDIATLIPVLLAHLHHERPVPEAASPPAPQ 1287 + Q+ + KP+ L +L + E EA P Q Sbjct: 1235 AESQQIRHVPFVNFLTKPVTSQILAEAVLNAI--EGKTMEAHPQPRSQ 1280 Score = 178 bits (452), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 120/352 (34%), Positives = 182/352 (51%), Gaps = 17/352 (4%) Query: 1149 LQGVQILLVEDNPVNRQVASELLALSGAQVTCADSGSMGVAMACDPARHFDLVLMDLQMP 1208 L G+ IL+VEDN +NRQV ELL+ GA V A+ G GV++ + FD+V+MD+QMP Sbjct: 1283 LAGLTILVVEDNQLNRQVIDELLSYEGANVVLAEGGMEGVSLVLESGDLFDIVIMDMQMP 1342 Query: 1209 GMDGIEATRRIRGQYELRGLPILAMTANASPEDKQRCIEAGMAGHIAKPIDIATLIPVLL 1268 MDG+EATRRIR LPILAMTANAS D+Q C+ AGM H+ KPID+ L+P +L Sbjct: 1343 DMDGLEATRRIRADERFAALPILAMTANASQSDRQECLNAGMNDHVGKPIDMPLLLPSIL 1402 Query: 1269 AHLHHERPVP---EAASPPAPQDLAEDRLCVEDYSSILHRFQQASDIYRTTLDAAGPELE 1325 + E E P A Q+ ++++L ++D IL RF ++ + PE+ Sbjct: 1403 RLVGREDMTSAEFEGHWPEATQEQSDEQL-LDDIRLILRRFGGNQSFFQKMAKSFAPEMM 1461 Query: 1326 RLLAQYCAALAMSPVRAQEAMAALAQASHALRGVTATIGARGLAAYFGALEQRCRQAMAG 1385 + LA + + + + AA+ SH ++G+ + GAR LAA+ LE++ +Q Sbjct: 1462 KQLALFKQS---TKIFDHSTAAAI---SHGIKGIASNFGARRLAAHAAYLEKQFKQ---- 1511 Query: 1386 RTPDLDWLERCRTEMDA-CQHDAMLVRQRLVMQALRPPASDAGPAAAALATVAASDFPDR 1444 P+L ++R ++ + + ++ SD A + S D Sbjct: 1512 ECPELIDIKRWTDTLEVLINQSSQQLSTYFEVEEFNAVISDNVEKAVYSSVSVQSVKTDL 1571 Query: 1445 QRLRELLLSNNLEALDLIETLGKRHGLTQQEPYRQLNRLIEKLDFAAALTCL 1496 L LL NNLEA+ L + L + L+ + L+ ++ LDF AL L Sbjct: 1572 NTLMNLLKENNLEAMALTDQLAEL--LSGHPQWSILHGQVQALDFNQALDTL 1621 >A9KUZ6.1 A9KUZ6_SHEB9 Multi-sensor hybrid histidine kinase Length = 1629 Score = 616 bits (1588), Expect = e-173, Method: Compositional matrix adjust. Identities = 450/1308 (34%), Positives = 683/1308 (52%), Gaps = 111/1308 (8%) Query: 29 LNERELHDSLAVDSRWIGDDIESLLRRYEHGLRGERGAILAIGEHALTRERMLRYMDSRD 88 +N +++ +L D+ I +++ + + Y++GLRG RG I+ GEH ++R RY +RD Sbjct: 35 MNAQKIEQALREDAEQISENVINRITLYQYGLRGARGTIVTAGEHDISRASFHRYSLTRD 94 Query: 89 LATEFPWAGGFGFIRHVPLSARAAYEQQVRQGRRLFPSITQLAENPGELYVIEYIEPIEA 148 + EFP A GFGFIR VP AA+ + RQ +I QL + GE YVIEYIEP++ Sbjct: 95 VDHEFPGARGFGFIRRVPSPDEAAFIARARQDDWPDFNIRQLNAHDGERYVIEYIEPVDR 154 Query: 149 NRKALGLDIASSQARRSAADHAMLTGRAELTPPIHLVQKDGASANAYLFLLPIYAGSVTP 208 N+ A+GLDIAS R++AAD AML+G L+ PI LVQ G ++L L PIY + P Sbjct: 155 NKAAVGLDIASEAHRKAAADAAMLSGEVRLSAPITLVQATGRPLQSFLILQPIYRTGLVP 214 Query: 209 PTLHERQEKIIGWAYAPLSVHDIISELSRRWKTHALEVLIKDAAADGDNVELFRSDGFDA 268 T +R GW+YAPL ++++ L+ K L L+ D + F + D Sbjct: 215 KTQQDRLSAGYGWSYAPLVTNEVLMGLALNQKMTKL--LLSDITQAERPISFFETHP-DE 271 Query: 269 LAQDSGLDSALS--LYGRTWKLQLRPSTDY-RQTHQFVSDRAMLLSCGSLLVLALVIALA 325 + S ++ ++GR W++++ + + H +L L+LA +IA+ Sbjct: 272 ASPLSAYRHKMTKDIFGRKWQIEVIAYPSFIKSLHLNQPSLVLLSGSLFSLLLAALIAMW 331 Query: 326 YQTYSRREEKLQQAQALLAAVVDSSPDAIVTTDAQGRISSWNRGAADYLPSSPAQALN-- 383 + R+++ L + QA A++++ S D I++ D +G+I+SWN+GA + A AL Sbjct: 332 SISLQRKQQVLLE-QARRASMLEHSLDGIISYDTKGQITSWNQGAEQLFGYTEAHALGQS 390 Query: 384 -TPLAQHPDLRDDLRARAASDASGQTTPH-IVSLQGAPVRYASAQVFA--LHDRAGRAVG 439 L + + RA A +G+T+ + I S Q + S A ++D G+ G Sbjct: 391 CCKLIVPASIVQEERALFAEVLAGKTSLNRITSHQRQDGSHLSTSTTAVPIYDEHGKIAG 450 Query: 440 KAFMLRDITHEKNIERQLQRINEELEWTVQQRTQALHQAKTMLQTVLNVMPSLVAY--WD 497 + +RDIT + ER + +N LE V +RT AL QA QT+L+ + + Y D Sbjct: 451 MSQTIRDITAQLEAERHILSLNASLERQVTKRTHALQQALLENQTLLDTINQQLLYSVTD 510 Query: 498 RHLINHFANAAYER--AFQRE--AGQLNGVYMPDLVGPALFEKALPHIEGVLAGAQQTFE 553 + + N + R + RE G+ + + + ++ I AG E Sbjct: 511 PNGVILEVNDNFCRISGYPREQLVGKTHAILQSGEHDASFWQSMWQQIN---AGQSWHGE 567 Query: 554 RSVDDPVLGARHMLTTYIPEIGDLGEVTGFYVVAHDVTEITHNRNQLSETLAQNQSLLDQ 613 D + T P + G++ F + D+T+ L Q Sbjct: 568 ICNLDKHQTLKWFDTVIGPVFDEYGKIERFVALRIDITD----------------RKLTQ 611 Query: 614 VQDAN--TLLNNVLSSAKGVAIIATDTEGLVTLFNSGAEQMLGYRAEDVVGK-------- 663 ++ N +LL NVL +A ++IIATD +G +T+FN GAE++LGY AE+++G+ Sbjct: 612 IEKNNLGSLLTNVLDAASEMSIIATDVQGNITIFNRGAERLLGYSAEEMIGQSTPAPLHL 671 Query: 664 LKEEHFSSRPEAALPGQD---------------SHT-ELLYRRHDGATLPVARQQTSMFD 707 L+E S +A G+D S T Y R DG+ V+ T+M D Sbjct: 672 LEEVMIRSAELSAEYGKDIQGFDVFIYKARAEGSETRNWTYVRKDGSQFQVSLSVTAMRD 731 Query: 708 HRQRHLGYLYIALDVSLQRQQASALAAARDQLVLAAEVAKLGVWVWDKDSDVLEYNPQVA 767 +GYL I +D+SL Q AL A + L AAEVA+LG+W W+ + LE+N ++ Sbjct: 732 SVGEIIGYLGIGVDISLMLLQQQALMTASNHLSKAAEVAQLGIWTWNLLGNSLEWNERMF 791 Query: 768 EIYGFGDRGGAPRVS--TYADWRRRVHPDDVDYVEKTLRAGLAVDGDHEPVFRVVRDDGG 825 IY D+ + R TY W RVHPDD+ + + L+ + ++P+FRVVR DG Sbjct: 792 AIY---DQPESLREQGLTYEHWSMRVHPDDIAFADAKLKGAVEGTAKYDPIFRVVRTDGS 848 Query: 826 IRYVQARAYVQRDGAGRPVRVICINLDITQRIEFENNLVDARLKAEQANSAKSLFLASVS 885 IR+VQA A V+RD G +RVI INLDIT++ + E +L +A+ +A+ A++AKS FLA++S Sbjct: 849 IRFVQAAAQVERDKQGHAIRVIGINLDITEQQQLEESLREAKQEADAASAAKSAFLANMS 908 Query: 886 HEIRTPMNGVLGMIQLLQRTQPLPAQQDYLDKAEISAKSLLNLLNDLLDFSKMDAKQLQL 945 HEIRTPMN VLGM+QL+Q T QQDY++K + +AKSLL LLND+LDFSK+D +L L Sbjct: 909 HEIRTPMNAVLGMLQLIQYTSLSRQQQDYVNKTQTAAKSLLGLLNDILDFSKIDVGKLIL 968 Query: 946 DPQAFELERFGHDLAAVLAGSPPQAGVRLHIALDPQLPRRLVGDAHRLQQVLVNLAGNAL 1005 D +E DLA VL+G+ V + LD LP L+ D RLQQ+LVNLAGNAL Sbjct: 969 DLHPCSIELLMRDLAVVLSGNHGDKDVEVMFDLDTALPPWLLADQLRLQQILVNLAGNAL 1028 Query: 1006 KFTHQGHIDVHFTRLDPLPGRTVALRVEVSDTGIGIAADRLDDIFDAFTQAEASTTRRYG 1065 KFTH G + V L TV +++ ++DTGIGI+ ++++ IF F QAE+ST+RR+G Sbjct: 1029 KFTHHGQVIVGIECLRH-EADTVTVQISITDTGIGISDEQIERIFTGFEQAESSTSRRFG 1087 Query: 1066 GTGLGLAISKHLVGLMGGQLQVSSEPGRGSRFWFDLQLAVDDDSVLGPAAADDAARPQPL 1125 GTGLGLAISK L+GLMG +L V+S+ G GSRFWFD+ + + Sbjct: 1088 GTGLGLAISKRLIGLMGSELHVTSKVGVGSRFWFDMTFPIIQ-----------------V 1130 Query: 1126 QAASHTAGSRAPETARAAPDAQCLQGVQILLVEDNPVNRQVASELLALSGAQVTCADSGS 1185 + HT L G ++L+V+DN + ++ ++L G +V A G Sbjct: 1131 EETRHTD----------------LSGYRVLVVDDNELTTEILEKILTGFGCEVETALGGY 1174 Query: 1186 MGVA---MACDPARHFDLVLMDLQMPGMDGIEATRRIRGQYELRGLPILAMTANASPE-- 1240 +A + + + FD+VLMD +MP +DG++ +R P++ M E Sbjct: 1175 AALAKVKQSHEKSTPFDVVLMDWRMPDLDGLQTAEMLRNSDANNQTPLVVMLTAYGHEVI 1234 Query: 1241 -DKQRCIEAGMAGHIAKPIDIATLIPVLLAHLHHERPVPEAASPPAPQ 1287 + Q+ + KP+ L +L + E EA P Q Sbjct: 1235 AESQQIRHVPFVNFLTKPVTSQILAEAVLNAI--EGKTMEAHPQPRSQ 1280 Score = 178 bits (452), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 120/352 (34%), Positives = 182/352 (51%), Gaps = 17/352 (4%) Query: 1149 LQGVQILLVEDNPVNRQVASELLALSGAQVTCADSGSMGVAMACDPARHFDLVLMDLQMP 1208 L G+ IL+VEDN +NRQV ELL+ GA V A+ G GV++ + FD+V+MD+QMP Sbjct: 1283 LAGLTILVVEDNQLNRQVIDELLSYEGANVVLAEGGMEGVSLVLESGDLFDIVIMDMQMP 1342 Query: 1209 GMDGIEATRRIRGQYELRGLPILAMTANASPEDKQRCIEAGMAGHIAKPIDIATLIPVLL 1268 MDG+EATRRIR LPILAMTANAS D+Q C+ AGM H+ KPID+ L+P +L Sbjct: 1343 DMDGLEATRRIRADERFAALPILAMTANASQSDRQECLNAGMNDHVGKPIDMPLLLPSIL 1402 Query: 1269 AHLHHERPVP---EAASPPAPQDLAEDRLCVEDYSSILHRFQQASDIYRTTLDAAGPELE 1325 + E E P A Q+ ++++L ++D IL RF ++ + PE+ Sbjct: 1403 RLVGREDMTSAEFEGHWPEATQEQSDEQL-LDDIRLILRRFGGNQSFFQKMAKSFAPEMM 1461 Query: 1326 RLLAQYCAALAMSPVRAQEAMAALAQASHALRGVTATIGARGLAAYFGALEQRCRQAMAG 1385 + LA + + + + AA+ SH ++G+ + GAR LAA+ LE++ +Q Sbjct: 1462 KQLALFKQS---TKIFDHSTAAAI---SHGIKGIASNFGARRLAAHAAYLEKQFKQ---- 1511 Query: 1386 RTPDLDWLERCRTEMDA-CQHDAMLVRQRLVMQALRPPASDAGPAAAALATVAASDFPDR 1444 P+L ++R ++ + + ++ SD A + S D Sbjct: 1512 ECPELIDIKRWTDTLEVLINQSSQQLSTYFEVEEFNAVISDNVEKAVYSSVSVQSVKTDL 1571 Query: 1445 QRLRELLLSNNLEALDLIETLGKRHGLTQQEPYRQLNRLIEKLDFAAALTCL 1496 L LL NNLEA+ L + L + L+ + L+ ++ LDF AL L Sbjct: 1572 NTLMNLLKENNLEAMALTDQLAEL--LSGHPQWSILHGQVQALDFNQALDTL 1621