BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0032.p (324 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IRC4.1 D8IRC4_HERSS Permease of the drug/metabolite transporte... 615 e-174 E5UBD0.1 E5UBD0_ALCXX Membrane protein 290 2e-76 Q1LEK4.1 Q1LEK4_RALME Putative membrane protein DUF6 289 4e-76 E3HK05.1 E3HK05_ACHXA Putative uncharacterized protein 286 2e-75 D4XB21.1 D4XB21_9BURK Putative uncharacterized protein 283 3e-74 Q2KZP3.1 Q2KZP3_BORA1 Putative membrane protein 266 3e-69 Q2RXX5.1 Q2RXX5_RHORT Putative uncharacterized protein 165 9e-39 B9CAX4.1 B9CAX4_9BURK Drug/metabolite transporter 161 1e-37 B9BQQ1.1 B9BQQ1_9BURK Drug/metabolite transporter 161 1e-37 C4LF80.1 C4LF80_TOLAT Putative uncharacterized protein 161 1e-37 >D8IRC4.1 D8IRC4_HERSS Permease of the drug/metabolite transporter (DMT) superfamily protein Length = 324 Score = 615 bits (1585), Expect = e-174, Method: Compositional matrix adjust. Identities = 321/324 (99%), Positives = 321/324 (99%) Query: 1 MSTAVATPTVPAAAARPAASSPAPAPMSRLFLVCVVLAICIWGGNWPVMKFGSQFIPPLW 60 MSTAVATPTVPAAAARPAA SPAPA MSRLFLVCVVLAICIWGGNWPVMKFGSQFIPPLW Sbjct: 1 MSTAVATPTVPAAAARPAALSPAPASMSRLFLVCVVLAICIWGGNWPVMKFGSQFIPPLW 60 Query: 61 FAASRFLSAAILSFVIAVVLCKLRLPTRQEWPVVVGVGVLQMGLFTALVTGALHFVMPGR 120 FAASRFLSAAILSFVIAVVL KLRLPTRQEWPVVVGVGVLQMGLFTALVTGALHFVMPGR Sbjct: 61 FAASRFLSAAILSFVIAVVLGKLRLPTRQEWPVVVGVGVLQMGLFTALVTGALHFVMPGR 120 Query: 121 ASLIAYATSIWVVPGAALVLKQKLSPQQSLATVCSYAGMAVIVLPALLHADLHSMIGYLM 180 ASLIAYATSIWVVPGAALVLKQKLSPQQSLATVCSYAGMAVIVLPALLHADLHSMIGYLM Sbjct: 121 ASLIAYATSIWVVPGAALVLKQKLSPQQSLATVCSYAGMAVIVLPALLHADLHSMIGYLM 180 Query: 181 LGVASLSWAMNILQIKMSPGVKLDFALLPWQTLVAALPLSLLALAVDGAPSFLADPHAWG 240 LGVASLSWAMNILQIKMSPGVKLDFALLPWQTLVAALPLSLLALAVDGAPSFLADPHAWG Sbjct: 181 LGVASLSWAMNILQIKMSPGVKLDFALLPWQTLVAALPLSLLALAVDGAPSFLADPHAWG 240 Query: 241 VIAYTGPLATALTFLIVLQMTQRLSPVTVSVCMLGVPVVGLTLSSLVFGERLSSDLVLGM 300 VIAYTGPLATALTFLIVLQMTQRLSPVTVSVCMLGVPVVGLTLSSLVFGERLSSDLVLGM Sbjct: 241 VIAYTGPLATALTFLIVLQMTQRLSPVTVSVCMLGVPVVGLTLSSLVFGERLSSDLVLGM 300 Query: 301 GLLCLGLVLPALPSLGLRRLATKG 324 GLLCLGLVLPALPSLGLRRLATKG Sbjct: 301 GLLCLGLVLPALPSLGLRRLATKG 324 >E5UBD0.1 E5UBD0_ALCXX Membrane protein Length = 304 Score = 290 bits (742), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 154/258 (59%), Positives = 191/258 (74%) Query: 38 AICIWGGNWPVMKFGSQFIPPLWFAASRFLSAAILSFVIAVVLCKLRLPTRQEWPVVVGV 97 A+ IWGGNWPVMK G + PLW AASRF SAA++S V+ L +LR PTRQEWP+V GV Sbjct: 19 AVMIWGGNWPVMKLGLAHMSPLWLAASRFGSAALISVVVLAALRRLRWPTRQEWPLVAGV 78 Query: 98 GVLQMGLFTALVTGALHFVMPGRASLIAYATSIWVVPGAALVLKQKLSPQQSLATVCSYA 157 +LQMG FTAL AL +V PGRAS+IAYATSIWV+P ++LVLK++LS Q LAT SYA Sbjct: 79 ALLQMGAFTALALWALQYVAPGRASVIAYATSIWVIPLSSLVLKERLSAAQWLATALSYA 138 Query: 158 GMAVIVLPALLHADLHSMIGYLMLGVASLSWAMNILQIKMSPGVKLDFALLPWQTLVAAL 217 G+ VIV PA H++IG +ML AS +WA NI+Q++ + V+L ++PWQT +A + Sbjct: 139 GIGVIVAPAFSPWQAHTVIGLVMLLGASFAWACNIIQLRGNRHVRLGADMIPWQTAIATV 198 Query: 218 PLSLLALAVDGAPSFLADPHAWGVIAYTGPLATALTFLIVLQMTQRLSPVTVSVCMLGVP 277 PL+ LA DGAP FLA P AW VI YTGPLATALTF++VL MTQ+L PV S+ ML VP Sbjct: 199 PLAALAWLRDGAPLFLAVPDAWPVILYTGPLATALTFIVVLGMTQKLPPVATSIAMLCVP 258 Query: 278 VVGLTLSSLVFGERLSSD 295 V+GL +SSLVF ER+S D Sbjct: 259 VIGLIVSSLVFHERISPD 276 >Q1LEK4.1 Q1LEK4_RALME Putative membrane protein DUF6 Length = 312 Score = 289 bits (740), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 163/306 (53%), Positives = 219/306 (71%), Gaps = 3/306 (0%) Query: 19 ASSPAPAPMSRLFLVCVVLAICIWGGNWPVMKFGSQFIPPLWFAASRFLSAAILSFVIAV 78 ASS APA + ++ A+ IWGGNWPVMK G I PLWFAA RF SAA++SF++ Sbjct: 9 ASSRAPATTGFRSFLPLIGAVVIWGGNWPVMKMGLAHISPLWFAACRFGSAALISFLVLG 68 Query: 79 VLCKLRLPTRQEWPVVVGVGVLQMGLFTALVTGALHFVMPGRASLIAYATSIWVVPGAAL 138 L +LRLP+RQEWP+V+GVG+LQMG FTAL AL +V PGRAS+IAYAT+IWV+P ++L Sbjct: 69 ALRRLRLPSRQEWPLVIGVGLLQMGAFTALALWALQYVPPGRASVIAYATAIWVIPLSSL 128 Query: 139 VLKQKLSPQQSLATVCSYAGMAVIVLPALLHADLHSMIGYLMLGVASLSWAMNILQIKMS 198 VL ++ S Q LAT SYAG+AVIV PAL +LH+++G ML ASL+W+++I+Q++ + Sbjct: 129 VLGERPSRLQWLATAFSYAGIAVIVAPALGGWELHTVMGLTMLLGASLAWSVSIIQLRAN 188 Query: 199 PGVKLDFALLPWQTLVAALPLSLLALAVDGAPSFLADPHAWGVIAYTGPLATALTFLIVL 258 ++L ++PW+ VA +PL LA DGAP A W VIAYTGPLATALTF++VL Sbjct: 189 RAIRLGADMIPWECAVATVPLIALAWLRDGAPDLGAMVDIWPVIAYTGPLATALTFIVVL 248 Query: 259 QMTQRLSPVTVSVCMLGVPVVGLTLSSLVFGERLSSDLVLGMGLLCLGLVLPAL-PSLGL 317 +TQ L P S+ MLGVPV+GL LS++ + E++S DL +G+ L+ +G+V AL P LG Sbjct: 249 NVTQSLPPAATSIAMLGVPVIGLVLSTVAWHEQISLDLSIGLALIGMGVVTTALAPRLG- 307 Query: 318 RRLATK 323 RLA + Sbjct: 308 -RLAAR 312 >E3HK05.1 E3HK05_ACHXA Putative uncharacterized protein Length = 303 Score = 286 bits (733), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 157/266 (59%), Positives = 201/266 (75%) Query: 38 AICIWGGNWPVMKFGSQFIPPLWFAASRFLSAAILSFVIAVVLCKLRLPTRQEWPVVVGV 97 A+ IWGGNWPVMK G + PLW AASRF SAA++S ++ +L +LRLPTRQEWP+V GV Sbjct: 16 AVAIWGGNWPVMKLGLTHMSPLWLAASRFGSAALISALVLGMLGRLRLPTRQEWPLVAGV 75 Query: 98 GVLQMGLFTALVTGALHFVMPGRASLIAYATSIWVVPGAALVLKQKLSPQQSLATVCSYA 157 +LQMG FTAL AL +V PGRAS+IAYATSIWV+P ++L+LK++LS Q LAT SYA Sbjct: 76 ALLQMGAFTALALWALQYVAPGRASVIAYATSIWVIPLSSLILKERLSLAQWLATALSYA 135 Query: 158 GMAVIVLPALLHADLHSMIGYLMLGVASLSWAMNILQIKMSPGVKLDFALLPWQTLVAAL 217 G+ VIV PA H++IG ML AS +WA NI+Q++ + ++L ++PWQT +AAL Sbjct: 136 GIVVIVAPAFSPWQAHTVIGLAMLLGASFAWACNIIQLRGNRHIRLGADMIPWQTAIAAL 195 Query: 218 PLSLLALAVDGAPSFLADPHAWGVIAYTGPLATALTFLIVLQMTQRLSPVTVSVCMLGVP 277 PL+ LA DGAP FLA+P AW VI YTGPLATALTF++VL MTQ++ PV S+ ML VP Sbjct: 196 PLAALAWLRDGAPVFLAEPQAWPVILYTGPLATALTFIVVLGMTQKMPPVATSIAMLCVP 255 Query: 278 VVGLTLSSLVFGERLSSDLVLGMGLL 303 V+GL +SSLVF ER+S+DL LG+ L+ Sbjct: 256 VIGLIVSSLVFQERISADLALGLALI 281 >D4XB21.1 D4XB21_9BURK Putative uncharacterized protein Length = 303 Score = 283 bits (723), Expect = 3e-74, Method: Compositional matrix adjust. Identities = 145/258 (56%), Positives = 191/258 (74%) Query: 38 AICIWGGNWPVMKFGSQFIPPLWFAASRFLSAAILSFVIAVVLCKLRLPTRQEWPVVVGV 97 A+ +WGGNWPVMK G + PLW AASRF SAA++S ++ + +LR PTRQEWP+V GV Sbjct: 16 AVMVWGGNWPVMKMGLAHMSPLWLAASRFGSAALVSVLVLAAVGRLRFPTRQEWPLVAGV 75 Query: 98 GVLQMGLFTALVTGALHFVMPGRASLIAYATSIWVVPGAALVLKQKLSPQQSLATVCSYA 157 +LQMG FTAL AL +V PGRAS++AYATSIWV+P +AL+LK++L+ Q LAT SYA Sbjct: 76 ALLQMGAFTALALWALQYVAPGRASVVAYATSIWVIPLSALILKERLNAGQWLATGLSYA 135 Query: 158 GMAVIVLPALLHADLHSMIGYLMLGVASLSWAMNILQIKMSPGVKLDFALLPWQTLVAAL 217 G+ VIV PA H+++G +ML AS +WA NI+Q++ V+L ++PWQT +A + Sbjct: 136 GIGVIVAPAFSPWQAHTVVGLIMLLGASFAWACNIIQLRGHRHVRLGADMIPWQTALATV 195 Query: 218 PLSLLALAVDGAPSFLADPHAWGVIAYTGPLATALTFLIVLQMTQRLSPVTVSVCMLGVP 277 PL+ LA DGAP FLA P AW +I YTGPLATALTF++VL MTQ++ PV S+ ML VP Sbjct: 196 PLAALAWLRDGAPGFLAVPDAWPIILYTGPLATALTFIVVLGMTQKMPPVATSIAMLCVP 255 Query: 278 VVGLTLSSLVFGERLSSD 295 V+GL +SS+VF ER+S+D Sbjct: 256 VIGLIVSSVVFHERISAD 273 >Q2KZP3.1 Q2KZP3_BORA1 Putative membrane protein Length = 307 Score = 266 bits (680), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 147/286 (51%), Positives = 197/286 (68%) Query: 35 VVLAICIWGGNWPVMKFGSQFIPPLWFAASRFLSAAILSFVIAVVLCKLRLPTRQEWPVV 94 ++ A+ +WGGNWP+MK G + PLW AA RF SA ++S ++ L +LR P+ +WP+V Sbjct: 13 LICAVFVWGGNWPIMKLGLAHMSPLWLAACRFGSATLVSLLVLGALGRLRRPSAAQWPLV 72 Query: 95 VGVGVLQMGLFTALVTGALHFVMPGRASLIAYATSIWVVPGAALVLKQKLSPQQSLATVC 154 GVG+LQM FTAL AL +V PGRAS+IAYATS+WV+P +AL LK++LS Q LAT+ Sbjct: 73 AGVGLLQMAAFTALALWALQYVPPGRASIIAYATSVWVIPLSALWLKERLSAVQWLATLL 132 Query: 155 SYAGMAVIVLPALLHADLHSMIGYLMLGVASLSWAMNILQIKMSPGVKLDFALLPWQTLV 214 SYAG+ +IV PA ++G ML AS +WA NI+Q++ V+L ++PWQT + Sbjct: 133 SYAGIGMIVAPAFSPWQPQLVVGLGMLLGASFAWACNIVQLRAGRSVRLGVEMIPWQTGL 192 Query: 215 AALPLSLLALAVDGAPSFLADPHAWGVIAYTGPLATALTFLIVLQMTQRLSPVTVSVCML 274 A LPL LA DGAP FLA P W +IAYTGPLATALTF++VL MTQR+ PV S+ ML Sbjct: 193 ACLPLIALAWLRDGAPVFLAQPEVWPLIAYTGPLATALTFIVVLTMTQRMPPVATSIAML 252 Query: 275 GVPVVGLTLSSLVFGERLSSDLVLGMGLLCLGLVLPALPSLGLRRL 320 VP++GL +SS VF ERLS+DL+ G+ + +++ AL L RL Sbjct: 253 CVPLIGLVVSSWVFKERLSADLLWGLVFIGASVMVSALGEKCLPRL 298 >Q2RXX5.1 Q2RXX5_RHORT Putative uncharacterized protein Length = 334 Score = 165 bits (417), Expect = 9e-39, Method: Compositional matrix adjust. Identities = 109/295 (36%), Positives = 167/295 (56%), Gaps = 5/295 (1%) Query: 32 LVCVVLAICIWGGNWPVMKFGSQFIPPLWFAASRFLSAAILSFVIAVVLCKLRLPTRQEW 91 LV + + + +WG +WPVMK PPLW AA RF S+ + F +LRLP R +W Sbjct: 25 LVWLGVMVALWGFSWPVMKICVGLAPPLWLAAIRFTSSGLCLFAFLACRGELRLPPRADW 84 Query: 92 PVVVGVGVLQMGLFTALVTGALHFVMPGRASLIAYATSIWVVPGAALVLKQKLSPQQSLA 151 P+V VG LQM FT L A+ + GRA+L+AY T +W V A + Q+ + Q +A Sbjct: 85 PIVASVGGLQMMAFTGLGLVAMQYTDAGRAALLAYTTPLWAVVTAWIAFGQRPTAAQGVA 144 Query: 152 TVCSYAGMAVIVLPALLH-ADLHSMIGYLMLGVASLSWAMNILQIKMSPGVKLDFALLPW 210 +G+AVI PA + D ++G +L ++++ W+ IL ++ L PW Sbjct: 145 LCVGLSGVAVICSPADMDWGDSTVLLGNALLLLSAMCWSFVILHVRRHRFTARPIDLAPW 204 Query: 211 QTLVAALPLSLLALAVDGAPSFLA-DPHAWGVIAYTGPLATALTFLIVLQMTQRLSPVTV 269 Q L+AALPL ++A +VDG+P +A P G + Y GP+AT+ F+I + +R+S + Sbjct: 205 QMLLAALPLIVIAASVDGSPLTIAWTPELIGFLIYFGPIATSACFVISSEYGRRVSAFAM 264 Query: 270 SVCMLGVPVVGLTLSSLVFGERLSSDLVLGMGLLCLGLVLPALPSLGLRRLATKG 324 S LGVPV+G+ S + GER++ L++G+ L+ G+ AL +L + R A G Sbjct: 265 SNITLGVPVIGMLSSIFLLGERVTVPLIIGLTLIVSGV---ALAALAVNRKAAAG 316 >B9CAX4.1 B9CAX4_9BURK Drug/metabolite transporter Length = 307 Score = 161 bits (408), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 115/297 (38%), Positives = 163/297 (54%), Gaps = 8/297 (2%) Query: 16 RPAASSPAPAPMSRLFLVCVVLAICIWGGNWPVMKFGSQFIPPLWFAASRFLSAAILSFV 75 R AA++P+ L L +AI +WG NWP MK G I P+W +A RF S A+ FV Sbjct: 11 RRAAAAPSSTYGGALLLG---VAIFLWGANWPAMKLGLAHITPIWLSAMRFASGALCLFV 67 Query: 76 IAVVLCKLRLPTRQEWPVVVGVGVLQMGLFTALVTGALHFVMPGRASLIAYATSIWVVPG 135 + V +R+P R + P + VG+LQM FTAL ALH V GR++++AY T IWV P Sbjct: 68 VQAVTGTVRVPQRGDLPFLASVGLLQMLAFTALSAIALHRVGAGRSAVLAYTTPIWVAPV 127 Query: 136 AALVLKQKLSPQQSLATVCSYAGMAVIVLPALLHADLHS---MIGYLMLGVASLSWAMNI 192 + L +++LS + + T AG+ ++ P L D H ++ +ML ASL WA+ I Sbjct: 128 SVLAFRERLSARAAFGTALGVAGVLLLFNP--LDVDWHDRQAVLANIMLLAASLCWAVCI 185 Query: 193 LQIKMSPGVKLDFALLPWQTLVAALPLSLLALAVDGAPSFLADPHAWGVIAYTGPLATAL 252 L ++ V +AL PWQ LVAA+PL LA V+G + + Y GP+ATA Sbjct: 186 LHLRHFRSVSSAYALAPWQMLVAAVPLVALAAVVEGPYTGDGSVALASALFYIGPIATAF 245 Query: 253 TFLIVLQMTQRLSPVTVSVCMLGVPVVGLTLSSLVFGERLSSDLVLGMGLLCLGLVL 309 F V R+S +++ MLGVPVVGL S L E L++ L + L+ G+ L Sbjct: 246 CFCAVNAANTRMSSTSMATAMLGVPVVGLITSVLFLHEHLTAGLATSVALIVAGIAL 302 >B9BQQ1.1 B9BQQ1_9BURK Drug/metabolite transporter Length = 307 Score = 161 bits (408), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 115/297 (38%), Positives = 163/297 (54%), Gaps = 8/297 (2%) Query: 16 RPAASSPAPAPMSRLFLVCVVLAICIWGGNWPVMKFGSQFIPPLWFAASRFLSAAILSFV 75 R AA++P+ L L +AI +WG NWP MK G I P+W +A RF S A+ FV Sbjct: 11 RRAAAAPSSTYGGALLLG---VAIFLWGANWPAMKLGLAHITPIWLSAMRFASGALCLFV 67 Query: 76 IAVVLCKLRLPTRQEWPVVVGVGVLQMGLFTALVTGALHFVMPGRASLIAYATSIWVVPG 135 + V +R+P R + P + VG+LQM FTAL ALH V GR++++AY T IWV P Sbjct: 68 VQAVTGTVRVPQRGDLPFLASVGLLQMLAFTALSAIALHRVGAGRSAVLAYTTPIWVAPV 127 Query: 136 AALVLKQKLSPQQSLATVCSYAGMAVIVLPALLHADLHS---MIGYLMLGVASLSWAMNI 192 + L +++LS + + T AG+ ++ P L D H ++ +ML ASL WA+ I Sbjct: 128 SVLAFRERLSARAAFGTALGVAGVLLLFNP--LDVDWHDRQAVLANIMLLAASLCWAVCI 185 Query: 193 LQIKMSPGVKLDFALLPWQTLVAALPLSLLALAVDGAPSFLADPHAWGVIAYTGPLATAL 252 L ++ V +AL PWQ LVAA+PL LA V+G + + Y GP+ATA Sbjct: 186 LHLRHFRSVSSAYALAPWQMLVAAVPLVALAAVVEGPYTGDGSVALASALFYIGPIATAF 245 Query: 253 TFLIVLQMTQRLSPVTVSVCMLGVPVVGLTLSSLVFGERLSSDLVLGMGLLCLGLVL 309 F V R+S +++ MLGVPVVGL S L E L++ L + L+ G+ L Sbjct: 246 CFCAVNAANTRMSSTSMATAMLGVPVVGLITSVLFLHEHLTAGLATSVALIVAGIAL 302 >C4LF80.1 C4LF80_TOLAT Putative uncharacterized protein Length = 311 Score = 161 bits (408), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 104/295 (35%), Positives = 168/295 (56%) Query: 14 AARPAASSPAPAPMSRLFLVCVVLAICIWGGNWPVMKFGSQFIPPLWFAASRFLSAAILS 73 A+ + S A A S L+ + + + +WG +WP MK I PLW AA RF SAA+ Sbjct: 3 ASNTISISYADARTSSGDLLKLGIMVLLWGFSWPAMKICLLSISPLWLAAIRFGSAALCL 62 Query: 74 FVIAVVLCKLRLPTRQEWPVVVGVGVLQMGLFTALVTGALHFVMPGRASLIAYATSIWVV 133 F+ + +L+ P +Q+ P++ VG+LQM FT L A+ V G+A+L+AY T +WV Sbjct: 63 FLFTGIRGELKFPVKQDIPIIASVGLLQMMAFTVLGLIAMTKVAAGQAALLAYTTPLWVS 122 Query: 134 PGAALVLKQKLSPQQSLATVCSYAGMAVIVLPALLHADLHSMIGYLMLGVASLSWAMNIL 193 +VL++ L Q A + G+ V+ P+LL+ ++IG +ML A+L W++ I+ Sbjct: 123 LITVVVLRRSLGKSQLYAVIAGLLGIVVVFSPSLLNGQSAAIIGDIMLLGAALCWSIVIV 182 Query: 194 QIKMSPGVKLDFALLPWQTLVAALPLSLLALAVDGAPSFLADPHAWGVIAYTGPLATALT 253 ++ L PWQ L++ALPL ++AL +G P + ++ + GPLAT Sbjct: 183 HVRQHQWHSSPLMLAPWQMLLSALPLMIIALITEGIPHINWNTELVSLLVFIGPLATCFC 242 Query: 254 FLIVLQMTQRLSPVTVSVCMLGVPVVGLTLSSLVFGERLSSDLVLGMGLLCLGLV 308 F+I L + +R++ V++SV LGVPV+GL S L GE+++ + +G+ L+ LV Sbjct: 243 FVISLAVGRRINSVSMSVATLGVPVIGLFSSILFLGEKITLAIAVGVVLILCSLV 297