BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0021.p (716 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IRD2.1 D8IRD2_HERSS GGDEF domain containing protein 1445 0.0 A6T250.1 A6T250_JANMA Putative uncharacterized protein 684 0.0 A4G8F7.1 A4G8F7_HERAR Putative uncharacterized protein 648 0.0 D9SHG7.1 D9SHG7_GALCS Diguanylate cyclase/phosphodiesterase with... 312 1e-82 Q2SJI5.1 Q2SJI5_HAHCH FOG: GGDEF domain 293 5e-77 C6XAD7.1 C6XAD7_METSD Diguanylate cyclase with PAS/PAC and GAF s... 289 1e-75 E4QMJ3.1 E4QMJ3_METS6 Diguanylate cyclase with PAS/PAC and GAF s... 288 2e-75 A4TYP2.1 A4TYP2_9PROT PAS:GGDEF 276 1e-71 Q2SIG3.1 Q2SIG3_HAHCH FOG: GGDEF domain 270 5e-70 Q2SHY3.1 Q2SHY3_HAHCH FOG: GGDEF domain 266 7e-69 >D8IRD2.1 D8IRD2_HERSS GGDEF domain containing protein Length = 738 Score = 1445 bits (3741), Expect = 0.0, Method: Compositional matrix adjust. Identities = 714/716 (99%), Positives = 715/716 (99%) Query: 1 LNKKKAPSPPNLSSLITLGVVVTVLVTTVSVLILVDQFTRGYARSEVETRLKQLAWQMQD 60 LNKKKAPSPPNLSSLITLGVVVTVLVTTVSVLILVDQFTRGYARSEVETRLKQLAWQMQD Sbjct: 23 LNKKKAPSPPNLSSLITLGVVVTVLVTTVSVLILVDQFTRGYARSEVETRLKQLAWQMQD 82 Query: 61 ALERGMAEREIDIRLLVSRPSIRQAQDPAHIRAVLEELQRNVPHYAWIGMARPDGTVLAA 120 ALERGMAEREIDIRLLVSRPSIRQAQDPAHIRAVLEELQRNVPHYAWIGMARPDGTVLAA Sbjct: 83 ALERGMAEREIDIRLLVSRPSIRQAQDPAHIRAVLEELQRNVPHYAWIGMARPDGTVLAA 142 Query: 121 TKGLLEGMSVAERPWFQQGQQTEYAADYHPAVLLEKKLPPQSDPWRFVDLSMPVLNMQGQ 180 TKGLLEGMSVAERPWFQQGQQTEYAADYHPAVLLEKKLPPQSDPWRFVDLSMPVLNMQGQ Sbjct: 143 TKGLLEGMSVAERPWFQQGQQTEYAADYHPAVLLEKKLPPQSDPWRFVDLSMPVLNMQGQ 202 Query: 181 MIGVMGMHLSWGWAREIASKLLNPTSSRYDVDVLIVRSDGTVILGPKDMEETKIDTASFR 240 MIGVMGMHLSWGWAREIASKLLNPTSSRYDVDVLIVRSDGTVILGPKDMEETKIDTASFR Sbjct: 203 MIGVMGMHLSWGWAREIASKLLNPTSSRYDVDVLIVRSDGTVILGPKDMEETKIDTASFR 262 Query: 241 AAQHSSAGGSLIETWPDDRRYVTGYARTGQGGEMKLKWTVIVRQPETVALEAFRDLERRV 300 AAQHSSAGGSLIETWPD RRYVTGYARTGQGGEMKLKWTVIVRQPETVALEAFRDLERRV Sbjct: 263 AAQHSSAGGSLIETWPDGRRYVTGYARTGQGGEMKLKWTVIVRQPETVALEAFRDLERRV 322 Query: 301 IVVGALAGAVLVLLAFMLTRRLVAPINALSAALEQRAAGLQEVKIPLVTSVRELQLLSSA 360 IVVGALAGAVLVLLAFMLTRRLVAPINALSAALEQRAAGLQEV+IPLVTSVRELQLLSSA Sbjct: 323 IVVGALAGAVLVLLAFMLTRRLVAPINALSAALEQRAAGLQEVEIPLVTSVRELQLLSSA 382 Query: 361 LGTMVEREERYLREMRSLNESLEERVVERTSRLHETATALQQALDQQQTNQIQLEESAAE 420 LGTMVEREERYLREMRSLNESLEERVVERTSRLHETATALQQALDQQQTNQIQLEESAAE Sbjct: 383 LGTMVEREERYLREMRSLNESLEERVVERTSRLHETATALQQALDQQQTNQIQLEESAAE 442 Query: 421 LRAILENAQDAFIAADEHGHIVEWNRQAELLLGWPRDTVMGRSMAELIIPSDMRAAHNHG 480 LRAILENAQDAFIAADEHGHIVEWNRQAELLLGWPRDTVMGRSMAELIIPSDMRAAHNHG Sbjct: 443 LRAILENAQDAFIAADEHGHIVEWNRQAELLLGWPRDTVMGRSMAELIIPSDMRAAHNHG 502 Query: 481 MAQFLKDGTSVVINNRIELQALHRDGHELPVEITVGHVKRQSGHLFIAFLHDITERLAFR 540 MAQFLKDGTSVVINNRIELQALHRDGHELPVEITVGHVKRQSGHLFIAFLHDITERLAFR Sbjct: 503 MAQFLKDGTSVVINNRIELQALHRDGHELPVEITVGHVKRQSGHLFIAFLHDITERLAFR 562 Query: 541 DQMRELALTDVLTSLPNRRAFSDRLPEGMMRARRAHQLLALFFMDLDGFKGINDRYGHEA 600 DQMRELALTDVLTSLPNRRAFSDRLPEGMMRARRAHQLLALFFMDLDGFKGINDRYGHEA Sbjct: 563 DQMRELALTDVLTSLPNRRAFSDRLPEGMMRARRAHQLLALFFMDLDGFKGINDRYGHEA 622 Query: 601 GDELLVEFARRLQASVRDVDTVARLAGDEFVVILENLQSQQDAIMVAEKILHAIREPFEL 660 GDELLVEFARRLQASVRDVDTVARLAGDEFVVILENLQSQQDAIMVAEKILHAIREPFEL Sbjct: 623 GDELLVEFARRLQASVRDVDTVARLAGDEFVVILENLQSQQDAIMVAEKILHAIREPFEL 682 Query: 661 THSTVHISSSIGVAVYQPDLDGEIGPEELLSMADKAMYAAKRLGKNRIELGRVGDF 716 THSTVHISSSIGVAVYQPDLDGEIGPEELLSMADKAMYAAKRLGKNRIELGRVGDF Sbjct: 683 THSTVHISSSIGVAVYQPDLDGEIGPEELLSMADKAMYAAKRLGKNRIELGRVGDF 738 >A6T250.1 A6T250_JANMA Putative uncharacterized protein Length = 719 Score = 684 bits (1764), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/706 (49%), Positives = 486/706 (68%), Gaps = 5/706 (0%) Query: 3 KKKAPSPPNLSSLITLGVVVTVLVTTVSVLILVDQFTRGYARSEVETRLKQLAWQMQDAL 62 + K P L++L+T+GV TV+VT +++L+L+D F YA+ + RL+QL+WQM+D+L Sbjct: 14 RPKTPERLRLATLVTIGVCATVIVTMLTLLVLIDHFAATYAKQQAHERLQQLSWQMRDSL 73 Query: 63 ERGMAEREIDIRLLVSRPSIRQAQDPAHIRAVLEELQRNVPHYAWIGMARPDGTVLAATK 122 +RGM +++ +R AQ+PA +R V + + +N P YAWIG+ P G V++A+ Sbjct: 74 DRGMGRMIDHAQVIADLVPVRDAQNPAEMRRVFDNVHKNFPDYAWIGLTDPKGIVVSASG 133 Query: 123 GLLEGMSVAERPWFQQGQQTEYAADYHPAVLLEKKLPPQSDPWRFVDLSMPVLNMQGQMI 182 GLLEG+ V++RPWFQ G Q + DYHPAVLLE KLP + WRFVD+++PV G Sbjct: 134 GLLEGVDVSKRPWFQGGAQQVFIGDYHPAVLLEDKLPESEERWRFVDVALPVTRSDGSYR 193 Query: 183 GVMGMHLSWGWAREIASKLLNPTSSRYDVDVLIVRSDGTVILGPKDMEETKIDTASFRAA 242 GV+G+HLSW WAR IA+ LL P +Y V+V++VR+DG V+LGP +EE+ I T S A Sbjct: 194 GVLGIHLSWNWARGIANSLLVPADRQYMVEVIVVRNDGMVMLGPDYLEESTITTTSLDLA 253 Query: 243 QHSSAGGSLIETWPDDRRYVTGYARTG-QGGEMKLKWTVIVRQPETVALEAFRDLERRVI 301 H+ + G++ E WPD RRY+TGY++TG + G LKW V++RQPE +AL FR+L+++V+ Sbjct: 254 -HTGSTGAIAEKWPDGRRYLTGYSQTGARAGHPSLKWAVLIRQPEEIALADFRELQQQVL 312 Query: 302 VVGALAGAVLVLLAFMLTRRLVAPINALSAALEQRAAGLQEVKIPLVTSVRELQLLSSAL 361 VGA G +L L+A L R+L P++ LSAA+ QR G IP++ E+ LLS L Sbjct: 313 WVGAALGLLLALIAVALARQLARPLDDLSAAITQRKEG-TGTAIPVIDGYHEVHLLSLTL 371 Query: 362 GTMVEREERYLREMRSLNESLEERVVERTSRLHETATALQQALDQQQTNQIQLEESAAEL 421 MV RE++++ ++R+LNE+LE V ERT + + A AL+ AL QQ Q +L+ES AEL Sbjct: 372 ADMVGREQQHVGKLRALNENLEHLVQERTQEIEQKAQALEDALQQQLAIQERLQESEAEL 431 Query: 422 RAILENAQDAFIAADEHGHIVEWNRQAELLLGWPRDTVMGRSMAELIIPSDMRAAHNHGM 481 RA L+NA DAFI+ D+ G IV+WN QAE LLGW +G+ +AELI+P +R + + Sbjct: 432 RATLQNANDAFISMDQDGIIVDWNEQAEHLLGWTHKEAVGQPLAELIVPPTLRDGYERDL 491 Query: 482 AQFLKDGTSVVINNRIELQALHRDGHELPVEITVGHVKRQSGHLFIAFLHDITERLAFRD 541 FL G S +IN R+EL AL RDG E P+E+ V V R++G+LFIAFLHDITER + Sbjct: 492 QHFLLTGESNIINRRVELSALRRDGKEFPIELAVACVARRNGYLFIAFLHDITERKLLQA 551 Query: 542 QMRELALTDVLTSLPNRRAFSDRLPEGMMRARRAHQLLALFFMDLDGFKGINDRYGHEAG 601 + +AL D LT LPNRRA RLPE + RA R + LA+ F+DLDGFKG+ND YGHEAG Sbjct: 552 SLMGMALKDPLTDLPNRRALIQRLPESIARAARLGKPLAVLFLDLDGFKGVNDGYGHEAG 611 Query: 602 DELLVEFARRLQASVRDVDTVARLAGDEFVVILENLQSQQDAIMVAEKILHAIREPFELT 661 DELL A+RL +VR DTVARLAGDEFV++LE L DA+ VA+KILH +++PF LT Sbjct: 612 DELLRTIAQRLLGAVRTTDTVARLAGDEFVIVLEMLNGDSDAMDVADKILHTLQQPFTLT 671 Query: 662 HSTVHISSSIGVAVYQPDLDGEIGPEELLSMADKAMYAAKRLGKNR 707 +TV IS+SIG+A++ P + PE+L+++AD AMYAAK+ GKNR Sbjct: 672 AATVTISASIGIAMHWP--EDHTTPEQLITLADGAMYAAKKKGKNR 715 >A4G8F7.1 A4G8F7_HERAR Putative uncharacterized protein Length = 708 Score = 648 bits (1671), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/698 (49%), Positives = 466/698 (66%), Gaps = 6/698 (0%) Query: 12 LSSLITLGVVVTVLVTTVSVLILVDQFTRGYARSEVETRLKQLAWQMQDALERGMAEREI 71 L++L+T GV TV+VT +++ +L+D F YAR + RL+QL+WQM+D+L+ GM Sbjct: 11 LATLVTAGVCATVVVTMLALFVLIDHFAANYAREQARERLQQLSWQMRDSLDLGMQHAAN 70 Query: 72 DIRLLVSRPSIRQAQDPAHIRAVLEELQRNVPHYAWIGMARPDGTVLAATKGLLEGMSVA 131 R + P +R A D A IR + +++ P YAWIG+ G V A ++GLLEG V+ Sbjct: 71 HARTIADLPMVRDADDAAVIRQIFSNIRQYFPDYAWIGLTDRQGRVFAGSEGLLEGADVS 130 Query: 132 ERPWFQQGQQTEYAADYHPAVLLEKKLPPQSDPWRFVDLSMPVLNMQGQMIGVMGMHLSW 191 +R WF G+ + DYHPAVLLE KL WRFVD+++PV + G+ GV+G+HLSW Sbjct: 131 QRNWFSGGKIGLFTGDYHPAVLLENKLSRPDGSWRFVDIALPVTHSNGEFRGVLGVHLSW 190 Query: 192 GWAREIASKLLNPTSSRYDVDVLIVRSDGTVILGPKDMEETKIDTASFRAAQHSSAGGSL 251 WAR IA +LL PT +Y V+V++VR DG +ILGP +EET I+T S ++ S G ++ Sbjct: 191 DWARGIAHELLVPTDRQYQVEVIVVRDDGMIILGPDYLEETSINTDSLNLSRIGSTG-AI 249 Query: 252 IETWPDDRRYVTGYARTG-QGGEMKLKWTVIVRQPETVALEAFRDLERRVIVVGALAGAV 310 ETW D RRY+TGYA+TG + + +KW+V++RQPE +AL FR L+ ++++VG G + Sbjct: 250 AETWADGRRYLTGYAQTGLRNPDASVKWSVLIRQPEEIALADFRGLQHQILLVGGGIGLL 309 Query: 311 LVLLAFMLTRRLVAPINALSAALEQRAAGLQEVKIPLVTSVRELQLLSSALGTMVEREER 370 L L+A L RRL P++ LSAA+ ++ IP+ + RE+ LLS L +MVERE + Sbjct: 310 LALVAIALGRRLAKPLDDLSAAIVDQSKDGAIKAIPITNNYREVHLLSMTLASMVERERQ 369 Query: 371 YLREMRSLNESLEERVVERTSRLHETATALQQALDQQQTNQIQLEESAAELRAILENAQD 430 ++ + +LNE+LE V ERTS + + A AL+ +L QQ Q +L++S AELRAIL NA D Sbjct: 370 HVMHLHALNENLENLVHERTSEIEQKAMALEASLAQQLAIQARLQDSEAELRAILHNAND 429 Query: 431 AFIAADEHGHIVEWNRQAELLLGWPRDTVMGRSMAELIIPSDMRAAHNHGMAQFLKDGTS 490 AFIA D+ G IVEWN QAE LLGW R GR + ++IIP RAA+ + FL G S Sbjct: 430 AFIAIDQDGIIVEWNEQAEHLLGWTRTEACGRKVEQMIIPPAQRAAYAESLQDFLNTGAS 489 Query: 491 VVINNRIELQALHRDGHELPVEITVGHVKRQSGHLFIAFLHDITERLAFRDQMRELALTD 550 VIN R+E+ AL RDG E PVE+ V V R +G LFIAFLHDITER + + +AL D Sbjct: 490 KVINRRVEVSALRRDGLEFPVELAVASVPRHNGWLFIAFLHDITERQLLQATLTNMALKD 549 Query: 551 VLTSLPNRRAFSDRLPEGMMRARRAHQLLALFFMDLDGFKGINDRYGHEAGDELLVEFAR 610 LT LPNRRA +LPE ++RA R + LA+ F+DLDGFKGIND YGHEAGDELL + Sbjct: 550 ALTDLPNRRALMQKLPEAIVRAARLGKPLAVLFIDLDGFKGINDGYGHEAGDELLRTMGQ 609 Query: 611 RLQASVRDVDTVARLAGDEFVVILENLQSQQDAIMVAEKILHAIREPFELTHSTVHISSS 670 R+ VR DTV RLAGDEFVV+LE L DA+ VA+KIL AI++PF L+ +TV +S S Sbjct: 610 RIVGVVRATDTVVRLAGDEFVVVLEMLNGDADALEVADKILQAIQQPFVLSAATVTLSGS 669 Query: 671 IGVAVYQP-DLDGEIGPEELLSMADKAMYAAKRLGKNR 707 IG+A++ P DL E+L+++AD AMYAAK+ GKNR Sbjct: 670 IGIAMHWPQDL---THAEQLITLADGAMYAAKKQGKNR 704 >D9SHG7.1 D9SHG7_GALCS Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) Length = 935 Score = 312 bits (800), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 228/725 (31%), Positives = 353/725 (48%), Gaps = 70/725 (9%) Query: 1 LNK--KKAPSPPNLSSLITLGVVVTVLVTTVSV-LILVDQFTRGYARSE---VETRLKQL 54 +NK KK +L + I+L V VL+ + ++ D R SE E R K Sbjct: 1 MNKFLKKLHPGYSLRAQISLASAVMVLLLSAAIGFYAADVSKRQIEESEGNAFELRAKN- 59 Query: 55 AWQMQDALERGMAEREIDIRLLVSRPSIRQAQDP-AHIRAVLEELQRNVPHYAWIGMARP 113 D L+RGM ER +I+ IR P H R +L LQ YAWIG+ P Sbjct: 60 ---ALDVLDRGMFERSREIQNAAILNEIRDPLAPIEHKREILTRLQATFNAYAWIGICDP 116 Query: 114 DGTVLAATKGLLEGMSVAERPWFQQGQQTEYAADYHPAVLLEKKLP-PQSDPWRFVDLSM 172 DG L T LEG +++RPW +G+ Y D H A+LL K LP P + + VD++ Sbjct: 117 DGVGLVGTGRYLEGKDLSKRPWCSKGRDKTYIGDVHDALLLSKLLPNPSGEMFYLVDVAA 176 Query: 173 PVLNMQGQMIGVMGMHLSWGWAREIASKLLNPTSSRYDVDVLIVRSDGTVILGPKDMEET 232 PVL+ QG + GV+ H+ W WA E+ P D+ ++ SDGTV+ GP + Sbjct: 177 PVLDRQGVLQGVLCGHIFWRWAEEVLDSKKTPGK-----DIFLISSDGTVLSGPAKPQSK 231 Query: 233 KID--TASFRAAQHSSAGGSLIETWPDDRRYVTGYARTGQGGEMK-LKWTVIVRQPETVA 289 D A+ +A + +GGS + W D + Y+ G++++ E + L W +VRQ A Sbjct: 232 LADLSPAAMQAISTNQSGGSQLVKWNDGKTYLVGFSKSSGYREYQGLGWASLVRQDVNTA 291 Query: 290 LEAFRDLERRVIVVGALAGAVLVLLAFMLTRRLVAPINALSAALEQRAAGLQEVKIPLVT 349 R L++ + +VGA G + L +++ R+ PI+ +S A ++ A G E ++P Sbjct: 292 FAPARQLQQHIWLVGAALGLLFAWLGWLMAGRIARPISLISQAADKVAGGDLEYELPARL 351 Query: 350 SVRELQLLSSALGTMVEREERYLREMRSLNESLEERVVERTSRLHETATALQQALDQQQT 409 E+ LS+A+ H+ L + Q++ Sbjct: 352 GEGEVAHLSTAI--------------------------------HDMVVNLTHEIKQRKE 379 Query: 410 NQIQLEESAAELRAILENAQDAFIAADEHGHIVEWNRQAELLLGWPRDTVMGRSMAELII 469 + L SA + E+ +A + D +IV N+ + G+ D V+G+ Sbjct: 380 AEQGLRLSAK----VFESNTEAIMITDAEQNIVMVNQAFTQITGYGADEVLGQR------ 429 Query: 470 PSDMRAAHNHGMAQFLKDGTSVVINN--RIELQALHRDGHELPVEITVGHVKRQSGHL-- 525 + ++ HG + ++ N+ R E+ ++G P +T+ ++ ++ + Sbjct: 430 -PKLLSSGRHGPEFYEAFWHALRANDLWRGEIWNKRKNGEIFPEWVTISALRDETSQISH 488 Query: 526 FIAFLHDITERLAFRDQMRELALTDVLTSLPNRRAFSDRLPEGMMRARRAHQLLALFFMD 585 ++A DITER +++ LA DVLT LPNR SDR+ + A+R + +A+ F+D Sbjct: 489 YVAVFLDITERKKEEERINYLANYDVLTGLPNRYLLSDRIEQAFSSAQRNNFKVAVLFID 548 Query: 586 LDGFKGINDRYGHEAGDELLVEFARRLQASVRDVDTVARLAGDEFVVILENLQSQQDAIM 645 LD FK IND GH+ GD LL A RL+ +R DT+ARL GDEFV +L L S ++ I Sbjct: 549 LDYFKNINDSLGHDIGDALLKLVAARLKTCLRRSDTIARLGGDEFVALLSELDSSEEVIF 608 Query: 646 VAEKILHAIREPFELTHSTVHISSSIGVAVYQPDLDGEIGPEELLSMADKAMYAAKRLGK 705 VAEK++ ++ E F L + I+ SIG+ +Y PD DGE ELL AD AMY AK G+ Sbjct: 609 VAEKMIESLTEKFTLGEYQLSITPSIGICIY-PD-DGETSV-ELLRNADLAMYQAKDDGR 665 Query: 706 NRIEL 710 N + Sbjct: 666 NNFKF 670 >Q2SJI5.1 Q2SJI5_HAHCH FOG: GGDEF domain Length = 664 Score = 293 bits (751), Expect = 5e-77, Method: Compositional matrix adjust. Identities = 219/701 (31%), Positives = 342/701 (48%), Gaps = 63/701 (8%) Query: 11 NLSSLITLGVVVTVLVTTVSVLILVDQFTRGYARSEVETRLKQLAWQMQDALERGMAERE 70 + +L++L + V +TT V ++D R+E+ + +LA+QM D L+R M ER Sbjct: 4 GIRTLLSLTLAGIVFITTSLVNGIIDYEASHRLRNELGEQYSELAYQMADRLDREMFERL 63 Query: 71 IDIRLLVSRPSIRQAQDP-AHI-RAVLEELQRNVPHYAWIGMARPDGTVLAATKGLLEGM 128 D+ + S P+IR A + R +LE L+R +YAW+G+ +G VL AT GL+EGM Sbjct: 64 SDMINVSSLPTIRNLNGSQAELQRNILETLKRTYGYYAWVGLTDVNGVVLRATGGLMEGM 123 Query: 129 SVAERPWFQQGQQTEYAADYHPAVLLEKKLPPQSD---PWRFVDLSMPVLNMQGQMIGVM 185 V+ PW+++G Y D + LL+ + P Q D P R VD + P+L + G IGVM Sbjct: 124 DVSGLPWWKEGHLAPYVGDVRDSELLD-RYPRQGDPTRPLRIVDFAAPILGLDGAQIGVM 182 Query: 186 GMHLSWGWAREIASKLLNPTSSRYDVDVLIVRSDGTVILGPKDMEETKIDTASFRAAQHS 245 G HL+W W +E AS LL + D+++L++ DG V+L P++ TK+ + Sbjct: 183 GAHLNWDWVKEAASSLLQQRNR--DIELLVLSKDGDVLLAPENTPFTKVSLPDSLKGNET 240 Query: 246 SAGGSLIETWPDDRRYVTGYARTGQGGEMK-LKWTVIVRQPETVALEAFRDLERRVIVVG 304 I TWPD ++Y+TG++ T E L WTVI R+ + AL R L + + G Sbjct: 241 H-----IMTWPDGKKYLTGFSGTKGFLEYSGLGWTVIARREVSQALGPVRRLSAAIWMWG 295 Query: 305 ALAGAVLVLLAFMLTRRLVAPINALSAALEQRAAGLQEVKIPLVTSVRELQLLSSALGTM 364 + ++ +M+ R+ P+ L+A+ E + G + Sbjct: 296 GSITVIFAMIGWMVAARISRPLRELAASAEA---------------------VERTDGRL 334 Query: 365 VEREERYLREMRSLNESLEERVVERTSRLHETATALQQALDQQQTNQIQLEESAAELRAI 424 E RE+R L A ALQ LD+ + + L +EL+ + Sbjct: 335 AYSEAFAPREIRGL------------------AAALQDMLDKLRNREETLRRQYSELQML 376 Query: 425 LENAQDAFIAADEHGHIVEWNRQAELLLGWPRDTVMGRSMAELIIPSDMRAAHNHGMAQF 484 E + + + + N + V+GRS+ E I S++ + Q Sbjct: 377 YEGSPVGIVMIGRDLNCLRINSRLADWFELDNTQVVGRSINE--ISSELIEWTKPVVLQV 434 Query: 485 LKDGT-SVVINNRIELQALHRDGHELPVEITVGHVKRQSGHLFIAFLHDITERLAFRDQM 543 L G I +++ + H L + + + S + +A L I+E A R Q Sbjct: 435 LASGAPEFGIEMKMKGGGAGKTRHFLASCLPLFEEGKASA-VGVALL--ISEMTAQR-QA 490 Query: 544 RELALTDVLTSLPNRRAFSDRLPEGMMRARRAHQLLALFFMDLDGFKGINDRYGHEAGDE 603 A D LT LPNRR S + + + ARR ++ +A ++DLD FK +ND +GH GD Sbjct: 491 EYFATHDTLTGLPNRRFLSTFITQELAVARRQNKKVAALYLDLDRFKDVNDTHGHSVGDA 550 Query: 604 LLVEFARRLQASVRDVDTVARLAGDEFVVILENLQSQQDAIMVAEKILHAIREPFELTHS 663 LL E RRL+ VR+ D + RL GDEFVV+L +++ D +AE I+ ++ + + Sbjct: 551 LLQEVTRRLRQVVRESDLIVRLGGDEFVVVLLDIKGVSDLTRLAESIIRSLSATYLFGSA 610 Query: 664 TVHISSSIGVAVYQPDLDGEIGPEELLSMADKAMYAAKRLG 704 V S SIG+AVY D+ GE +LLS AD+AMY AK+ G Sbjct: 611 EVRTSPSIGIAVYPDDVSGE---SQLLSCADEAMYEAKKSG 648 >C6XAD7.1 C6XAD7_METSD Diguanylate cyclase with PAS/PAC and GAF sensors Length = 640 Score = 289 bits (740), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 150/337 (44%), Positives = 213/337 (63%), Gaps = 2/337 (0%) Query: 375 MRSLNESLEERVVERTSRLHETATALQQALDQQQTNQIQLEESAAELRAILENAQDAFIA 434 + L LE RV +RT L+++ L A+ +Q +L+E E+ ++ENA DA+++ Sbjct: 305 LNELQHELENRVAQRTFELNKSNEMLSFAMAKQTLAAQELKERELEISMVIENANDAYVS 364 Query: 435 ADEHGHIVEWNRQAELLLGWPRDTVMGRSMAELIIPSDMRAAHNHGMAQFLKDGTSVVIN 494 ++ G I WNRQAE+ GW +G+ + ++IIP M+ AH +GM + + G +VV+ Sbjct: 365 INQSGIITAWNRQAEITFGWSAREAIGQRLDQVIIPPHMQQAHLNGMQRHMDTGEAVVLG 424 Query: 495 NRIELQALHRDGHELPVEITVGHVKRQSGHLFIAFLHDITERLAFRDQMRELALTDVLTS 554 R+EL+A H+DGH +PVE+ + ++ H+F AFL DI+ER + + + A DVLT Sbjct: 425 KRLELEAKHKDGHIVPVEVRISKIEVHGKHIFSAFLTDISERKHLQSLLEKEAKHDVLTG 484 Query: 555 LPNRRAFSDRLPEGMMRARRAHQLLALFFMDLDGFKGINDRYGHEAGDELLVEFARRLQA 614 LPNRRAF++ LP + RA R Q +AL F+DLDGFK IND GH+AGD LL E A RL + Sbjct: 485 LPNRRAFTEALPLALARADRTQQWMALMFIDLDGFKQINDELGHDAGDMLLREIANRLNS 544 Query: 615 SVRDVDTVARLAGDEFVVILENLQSQQDAIMVAEKILHAIREPFELTHSTVHISSSIGVA 674 + R DTVAR AGDEFVV+LEN+ +Q A VA+KIL +R+P L IS S+G+A Sbjct: 545 ATRQTDTVARFAGDEFVVLLENMPEKQHAEGVAQKILTLLRDPVMLGGEPRQISCSLGLA 604 Query: 675 VYQPDLDGEIGPEELLSMADKAMYAAKRLGKNRIELG 711 Y P + + P+ LL AD AMY AKR GKN+I + Sbjct: 605 YYAP--NSHVQPDMLLKEADNAMYEAKRSGKNQIRIS 639 >E4QMJ3.1 E4QMJ3_METS6 Diguanylate cyclase with PAS/PAC and GAF sensors Length = 640 Score = 288 bits (738), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 149/337 (44%), Positives = 213/337 (63%), Gaps = 2/337 (0%) Query: 375 MRSLNESLEERVVERTSRLHETATALQQALDQQQTNQIQLEESAAELRAILENAQDAFIA 434 + L LE RV +RT L+++ L A+ +Q +L+E E+ ++ENA DA+++ Sbjct: 305 LNELQHELENRVAQRTFELNKSNEMLSFAMAKQTLAAQELKERELEISMVIENANDAYVS 364 Query: 435 ADEHGHIVEWNRQAELLLGWPRDTVMGRSMAELIIPSDMRAAHNHGMAQFLKDGTSVVIN 494 ++ G I WNRQAE+ GW +G+ + ++IIP M+ AH +GM + + G ++V+ Sbjct: 365 INQSGIITAWNRQAEITFGWSAREAIGQRLDQVIIPPHMQQAHLNGMQRHMDTGEALVLG 424 Query: 495 NRIELQALHRDGHELPVEITVGHVKRQSGHLFIAFLHDITERLAFRDQMRELALTDVLTS 554 R+EL+A H+DGH +PVE+ + ++ H+F AFL DI+ER + + + A DVLT Sbjct: 425 KRLELEAKHKDGHIVPVEVRISKIEVHGKHIFSAFLTDISERKHLQSLLEKEAKHDVLTG 484 Query: 555 LPNRRAFSDRLPEGMMRARRAHQLLALFFMDLDGFKGINDRYGHEAGDELLVEFARRLQA 614 LPNRRAF++ LP + RA R Q +AL F+DLDGFK IND GH+AGD LL E A RL + Sbjct: 485 LPNRRAFTEALPLALARADRTQQWMALMFIDLDGFKQINDELGHDAGDMLLREIANRLNS 544 Query: 615 SVRDVDTVARLAGDEFVVILENLQSQQDAIMVAEKILHAIREPFELTHSTVHISSSIGVA 674 + R DTVAR AGDEFVV+LEN+ +Q A VA+KIL +R+P L IS S+G+A Sbjct: 545 ATRQTDTVARFAGDEFVVLLENMPEKQHAEGVAQKILTLLRDPVMLGGEPRQISCSLGLA 604 Query: 675 VYQPDLDGEIGPEELLSMADKAMYAAKRLGKNRIELG 711 Y P + + P+ LL AD AMY AKR GKN+I + Sbjct: 605 YYAP--NSHVQPDMLLKEADNAMYEAKRSGKNQIRIS 639 >A4TYP2.1 A4TYP2_9PROT PAS:GGDEF Length = 953 Score = 276 bits (705), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 201/668 (30%), Positives = 332/668 (49%), Gaps = 47/668 (7%) Query: 51 LKQLAWQMQDALERGMAEREIDIRLLVSRPSIRQAQDP-AHIRAVLEELQRNVPHYAWIG 109 L + A Q+ ++ G+ ER +I++ I + P A + +LE L+ + P+YAWIG Sbjct: 51 LSEAAIQLAAHMDTGLYERWREIQVFAGMAEIVDPKAPLARKKQLLETLKNSYPNYAWIG 110 Query: 110 MARPDGTVLAATKGLLEGMSVAERPWFQQGQQTEYAADYHPAVLLEKKLP--PQSD-PWR 166 +G +LA T G+LEG SVA+R WFQ+G++ + D H A LL K +P P+ P R Sbjct: 111 FTDTEGNILAGTGGMLEGKSVAQRSWFQEGKKGPFLGDVHDAFLLAKLIPRDPKDPLPLR 170 Query: 167 FVDLSMPVLNMQGQMIGVMGMHLSWGWAREIASKLLNPTSSRYDVDVLIVRSDGTVILGP 226 +D+S P+++ G +GV+ HLSW W+REI ++ L P R V I+ +G +LG Sbjct: 171 LLDVSAPLISADGVFLGVLCGHLSWDWSREIKAQSLAPLQQRNLTGVHILNHEGKTVLGT 230 Query: 227 KDMEE-TKIDTASFRAAQHSSAGGSLIETWPDDRRYVTGYART-GQGGEMKLKWTVIVRQ 284 D+ + A+ G IE WPD + Y+TGYAR G G L W +++ Q Sbjct: 231 GDVASWPDVSNVPSVASAKQGMHGWTIENWPDGKSYLTGYARAKGTMGSPGLGWIILIHQ 290 Query: 285 PETVALEAFRD---LERRVIVVGALAGAVLVLLAFMLTRRLVAPINALSAALEQRAAGLQ 341 P EAF D +V++VG L ++ R + P+ ++ ++ G Sbjct: 291 PVD---EAFADAVLFRNQVMIVGFLVAVGAAAWLWLALGRTIRPLTRIAEIADRIQKGEA 347 Query: 342 EVKIPLVTSVRELQLLSSALGTMVEREERYLREMRSLNESLEERVVERTSRLHETATALQ 401 +IP++ E +LS +L +V ++ + N +LE+ + R Sbjct: 348 VAQIPIIDGRSEAHILSVSLNRLVSTLADRNADLAAANTALEDDIRRR------------ 395 Query: 402 QALDQQQTNQIQLEESAAELRAILENAQDAFIAADEHGHIVEWNRQAELLLGWPRDTVMG 461 +AL+Q+ E++AE I+ D G I N + G+ R V+G Sbjct: 396 EALEQELRLAATYYEASAE--GIVVTVAD--------GTIASVNDAFCRITGYQRHEVLG 445 Query: 462 RSMAELIIPSDMRAAHNHG-MAQFLKDGTSVVINNRIELQALHRDGHELPVEITVGHVKR 520 ++ + ++ S ++ + M Q L+D + E+ +DG P +T+ V+R Sbjct: 446 KTTS--LLKSGVQDDEFYADMWQLLRDTG----HWEGEIWNRRKDGRTFPEYLTINAVRR 499 Query: 521 QSGHL--FIAFLHDITERLAFRDQMRELALTDVLTSLPNRRAFSDRLPEGMMRARRAHQL 578 G + ++A D+++R A +++ +L+ D LT LP R +RL + ARR +L Sbjct: 500 D-GEITHYVAQFSDLSDRKAAEEKIVQLSTHDTLTGLPKRIVAMERLSGLISEARRDGRL 558 Query: 579 LALFFMDLDGFKGINDRYGHEAGDELLVEFARRLQASVRDVDTVARLAGDEFVVILENLQ 638 +AL +++LDG +ND GH GD +LVE A+RL+ ++ D +ARL GDEF++I Sbjct: 559 VALIYVNLDGLNRVNDALGHHGGDRVLVETAQRLRQLLQPADALARLGGDEFLIISSRFM 618 Query: 639 SQQDAIMVAEKILHAIREPFELTHSTVHISSSIGVAVYQPDLDGEIGPEELLSMADKAMY 698 +A +A +IL A + F + ++++ IG+A Y DGE P EL+ + A Sbjct: 619 VMAEAEALARQILDACSQAFFVDEKDTYLTARIGIAFYP--RDGE-DPLELIRNSHAASV 675 Query: 699 AAKRLGKN 706 AK G N Sbjct: 676 RAKEQGGN 683 >Q2SIG3.1 Q2SIG3_HAHCH FOG: GGDEF domain Length = 673 Score = 270 bits (691), Expect = 5e-70, Method: Compositional matrix adjust. Identities = 219/692 (31%), Positives = 339/692 (48%), Gaps = 71/692 (10%) Query: 24 VLVTTVSVLILVDQFTRGYARSEVETRLKQLAWQMQDALERGMAEREIDIRLLVSRPSIR 83 V+ TT V +VD + E++ + A Q+ + L+RG+ R DI + S P+IR Sbjct: 17 VIATTAVVSAIVDYEASLRLQKELDRQFIGAASQLAEDLDRGIYARLRDIINVSSLPTIR 76 Query: 84 QAQD--PAHIRAVLEELQRNVPHYAWIGMARPDGTVLAATKGLLEGMSVAERPWFQQGQQ 141 +D R +LE L++ +YAWIG +G VL AT GL+EGM+V+++ W+ G+ Sbjct: 77 YLRDGQEEERRNILEALKKTQEYYAWIGFTDENGLVLQATGGLMEGMNVSDQTWWLNGKA 136 Query: 142 TEYAADYHPAVLLEKKLPPQSDPW-RFVDLSMPVLNMQGQMIGVMGMHLSWGWAREIASK 200 Y D P + F++++ PV N QG +IG++G ++SW WA E+A+ Sbjct: 137 GPYVGDIRSLRQDGVDSPGFTTKLSNFIEMATPVRNSQGLVIGILGAYVSWDWASELAAN 196 Query: 201 LLNPTSSRYDVDVLIVRSDGTVILGPKDMEETKIDTASFRAAQHSSAGGSLIETWPDDRR 260 +L S + ++ L++ VILGP + +D + + ++ G + WPD R Sbjct: 197 VLRHQSQK--LEFLVLSQQHRVILGPDAL--LAMDIYLPDSLKANAIG---LTQWPDGER 249 Query: 261 YVTGYART-GQGGEMKLKWTVIVRQPETVALEAFRDLERRVIVVGALAGAVLVLLAFMLT 319 Y+TG+A T G L WTV+ RQ AL R L + GA AV LL + + Sbjct: 250 YLTGFADTKGFRSYKGLGWTVVARQQAETALAPVRQLRTAIWRWGAFIAAVFALLGWGIA 309 Query: 320 RRLVAPINALSAALEQRAAGLQEVKIPLVTSV-RELQLLSSALGTMVEREERYLREMRSL 378 +++ P+ +L+AA + G + V + S +E+ LLS ALG M+ + Sbjct: 310 KQISRPLKSLAAAAREIKDGARLVAFRMRQSAPQEIHLLSDALGDMMRQ----------- 358 Query: 379 NESLEERVVERTSRLHETATALQQALDQQQTNQIQLEESAAELRAILENAQDAFIAADEH 438 LE R ETA L+ AEL + E A + D++ Sbjct: 359 ---LESR---------ETA----------------LQRQYAELDMLYEGAPIGIVIVDQN 390 Query: 439 GHIVEWNRQAELLLGWPRDTVMGRSMAELIIPSDMRAAHNHGMAQFLKDGT------SVV 492 + N + G V GR + EL PS++ ++Q L GT +V+ Sbjct: 391 MRCLRMNGRLAEWSGLQNSVVNGRMITEL--PSELLTQFETPLSQTLLSGTPSYNAEAVI 448 Query: 493 INNRIELQALHRDGHELPVEITVGHVKRQSGHLFIAFLHDITERLAFRDQMRELALTDVL 552 + EL+ H LP+ QSG + A L I+E A R Q A D L Sbjct: 449 EDTSNELER-HFLAACLPL-----FEDGQSGPVGAALL--ISEMTAQR-QAEYFATHDSL 499 Query: 553 TSLPNRRAFSDRLPEGMMRARRAHQLLALFFMDLDGFKGINDRYGHEAGDELLVEFARRL 612 T L NRR + L + + ARR + LAL ++D+D FK +ND YGH+AGD LL E A RL Sbjct: 500 TGLANRRFLTAYLFQELAMARRRKRKLALLYLDMDRFKAVNDTYGHDAGDALLREVAFRL 559 Query: 613 QASVRDVDTVARLAGDEFVVILENLQSQQDAIMVAEKILHAIREPFELTHSTVHISSSIG 672 + R+ D ++RL GDEFV++ + ++ ++ +A+ ++ ++ P+ L + +H S SIG Sbjct: 560 KNVCRESDLISRLGGDEFVIVALDHKNLNNSARLAKSVVISLSRPYILGGAHIHTSPSIG 619 Query: 673 VAVYQPDLDGEIGPEELLSMADKAMYAAKRLG 704 +AVY D D E LL AD+AMY AK+ G Sbjct: 620 IAVYPDDADDET---TLLRYADEAMYEAKKSG 648 >Q2SHY3.1 Q2SHY3_HAHCH FOG: GGDEF domain Length = 658 Score = 266 bits (681), Expect = 7e-69, Method: Compositional matrix adjust. Identities = 135/311 (43%), Positives = 199/311 (63%), Gaps = 3/311 (0%) Query: 396 TATALQQALDQQQTNQIQLEESAAELRAILENAQDAFIAADEHGHIVEWNRQAELLLGWP 455 T L+Q + Q++ + QL+ S R I+E++ +AFIA + G I +WN +AE GW Sbjct: 334 TLMQLEQEVAQRKQIEEQLKASEMRTRRIIESSHEAFIAMNSSGFITDWNPKAEETFGWT 393 Query: 456 RDTVMGRSMAELIIPSDMRAAHNHGMAQFLKDGTSVVINNRIELQALHRDGHELPVEITV 515 +GR ++ELIIPS +R H GM +F++ G +V+ R+EL AL+ G ++PVEIT+ Sbjct: 394 ATEAIGRKLSELIIPSGLRERHELGMRKFIETGQGIVLGKRLELLALNIKGEKIPVEITI 453 Query: 516 GHVKRQSGHLFIAFLHDITERLAFRDQMRELALTDVLTSLPNRRAFSDRLPEGMMRARRA 575 + Q F AFLHDI+ER ++R LA D LTSLPNR F DRL + + R+ R Sbjct: 454 SAISAQEQWQFCAFLHDISERKQTEQKLRHLAQYDSLTSLPNRALFYDRLNQALARSHRN 513 Query: 576 HQLLALFFMDLDGFKGINDRYGHEAGDELLVEFARRLQASVRDVDTVARLAGDEFVVILE 635 L AL ++D+D FK IND +GH GDELL F+ R++ +R+ DT+ARL GDEFV+I E Sbjct: 514 QTLFALMYLDIDHFKSINDTHGHGVGDELLSAFSSRIRLIIRESDTLARLGGDEFVIIAE 573 Query: 636 NLQSQQDAIMVAEKILHAIREPFELTHSTVHISSSIGVAVYQPDLDGEIGPEELLSMADK 695 N+ Q DA +A+KIL A+++ F+L ++ + +SIGVA+ P + ++L+ MADK Sbjct: 574 NISVQGDAEHIAQKILWAMKQAFQLNELSIQVGTSIGVALPPPH---AVNADDLVKMADK 630 Query: 696 AMYAAKRLGKN 706 A+Y+AK G+N Sbjct: 631 ALYSAKAAGRN 641