BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0240.p (217 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IS39.1 D8IS39_HERSS Putative uncharacterized protein 438 e-121 A6T2R0.1 A6T2R0_JANMA GTP cyclohydrolase I 269 2e-70 A4G8Y9.1 A4G8Y9_HERAR NADPH-dependent 7-cyano-7-deazaguanine red... 265 3e-69 C3X6B9.1 C3X6B9_OXAFO GTP cyclohydrolase I 256 1e-66 C5AD36.1 C5AD36_BURGB GTP cyclohydrolase family protein 256 1e-66 A4JHT1.1 QUEF_BURVG NADPH-dependent 7-cyano-7-deazaguanine reduc... 253 1e-65 B1YWG4.1 QUEF_BURA4 NADPH-dependent 7-cyano-7-deazaguanine reduc... 253 1e-65 C5NFY3.1 C5NFY3_BURMA NADPH-dependent 7-cyano-7-deazaguanine red... 253 1e-65 C4ASW9.1 C4ASW9_BURMA PreQ(1) synthase EC=1.7.1.13 253 1e-65 B7CJ70.1 B7CJ70_BURPS NADPH-dependent 7-cyano-7-deazaguanine red... 253 1e-65 >D8IS39.1 D8IS39_HERSS Putative uncharacterized protein Length = 291 Score = 438 bits (1126), Expect = e-121, Method: Compositional matrix adjust. Identities = 214/215 (99%), Positives = 215/215 (100%) Query: 1 MDHTNPSASPASHSPESSPLGKSSQYPTHYDPSLLFPIPRAPKRAELQISGTLPFFGVDL 60 MDHTNPSASPASHSPESSPLGKSSQYPTHYDPSLLFPIPRAPKRAELQISGTLPFFGVDL Sbjct: 1 MDHTNPSASPASHSPESSPLGKSSQYPTHYDPSLLFPIPRAPKRAELQISGTLPFFGVDL 60 Query: 61 WTAYEISWLNLRGKPQIAIATFMVPADSPNIIESKSFKLYLNSFNQERLESADQLIDKMR 120 WTAYEISWLNLRGKPQIAIATFMVPADSPNIIESKSFKLYLNSFNQERLESADQLIDKMR Sbjct: 61 WTAYEISWLNLRGKPQIAIATFMVPADSPNIIESKSFKLYLNSFNQERLESADQLIDKMR 120 Query: 121 TDLSAAAGAQVQVALTEPAQFGQLQFGELSGLLLDRLDVEIEAAASGAHPDGSQLRANSE 180 TDLSAAAGAQVQVALTEPAQFGQLQFGELSGLLLDRLDVEIEAAASGAHPDGSQLRAN+E Sbjct: 121 TDLSAAAGAQVQVALTEPAQFGQLQFGELSGLLLDRLDVEIEAAASGAHPDGSQLRANTE 180 Query: 181 EATVEETLVSHLLKSNCPVTSQPDWGSVQIQYVGA 215 EATVEETLVSHLLKSNCPVTSQPDWGSVQIQYVGA Sbjct: 181 EATVEETLVSHLLKSNCPVTSQPDWGSVQIQYVGA 215 >A6T2R0.1 A6T2R0_JANMA GTP cyclohydrolase I Length = 279 Score = 269 bits (687), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 132/201 (65%), Positives = 155/201 (77%), Gaps = 4/201 (1%) Query: 14 SPESSPLGKSSQYPTHYDPSLLFPIPRAPKRAELQISGTLPFFGVDLWTAYEISWLNLRG 73 SP++SPLGK S Y T YDPSLLFPIPR KR EL +SG LPFFGVD+W AYE+SWLN+RG Sbjct: 6 SPDASPLGKPSVYQTQYDPSLLFPIPRQGKRDELGLSGDLPFFGVDIWNAYELSWLNMRG 65 Query: 74 KPQIAIATFMVPADSPNIIESKSFKLYLNSFNQERLESADQLIDKMRTDLSAAAGAQVQV 133 KPQ+AIA MVPADSPNI+ESKSFKLYLNSFNQ +L D L++ +R DLSA GA VQ+ Sbjct: 66 KPQVAIARIMVPADSPNIVESKSFKLYLNSFNQTKLGGTDALLELLRADLSAGFGAPVQI 125 Query: 134 ALTEPAQFGQLQFGELSGLLLDRLDVEIEAAASGAHPDGSQLRANSEEATVEETLVSHLL 193 LT P F ++ GEL G+LLDRLD+E+ PD S L+A ++A VEETL+S+LL Sbjct: 126 TLTLPEDFVKINIGELDGMLLDRLDIEVTDYV----PDPSLLQAAHDDAPVEETLLSNLL 181 Query: 194 KSNCPVTSQPDWGSVQIQYVG 214 KSNC VT QPDWGSVQI YVG Sbjct: 182 KSNCLVTGQPDWGSVQIHYVG 202 >A4G8Y9.1 A4G8Y9_HERAR NADPH-dependent 7-cyano-7-deazaguanine reductase (NADPH-dependent nitrile oxidoreductase) EC=1.7.1.- Length = 279 Score = 265 bits (677), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 129/202 (63%), Positives = 152/202 (75%), Gaps = 4/202 (1%) Query: 14 SPESSPLGKSSQYPTHYDPSLLFPIPRAPKRAELQISGTLPFFGVDLWTAYEISWLNLRG 73 P+ SPLGK + Y HYDPSLLF IPR KR E+ +SGTLPFFGVD+W AYEISWLN+RG Sbjct: 6 KPDGSPLGKPTAYEAHYDPSLLFSIPRQYKRDEIGLSGTLPFFGVDIWNAYEISWLNMRG 65 Query: 74 KPQIAIATFMVPADSPNIIESKSFKLYLNSFNQERLESADQLIDKMRTDLSAAAGAQVQV 133 KPQ+A+A VPADSPNI+ESKSFKLYLNS NQ +L + L++ +R DLS+ GA VQV Sbjct: 66 KPQVAMARVTVPADSPNIVESKSFKLYLNSLNQTKLGGTEALLELLREDLSSGFGAPVQV 125 Query: 134 ALTEPAQFGQLQFGELSGLLLDRLDVEIEAAASGAHPDGSQLRANSEEATVEETLVSHLL 193 LT P F ++ GEL+GLLLDRLD+E+ + PD + LRA +E VEETLVSHLL Sbjct: 126 TLTLPENFARVPMGELNGLLLDRLDIEVHEYS----PDPTLLRAARDEPVVEETLVSHLL 181 Query: 194 KSNCPVTSQPDWGSVQIQYVGA 215 KSNC VT QPDW SVQIQYVG Sbjct: 182 KSNCLVTGQPDWASVQIQYVGG 203 >C3X6B9.1 C3X6B9_OXAFO GTP cyclohydrolase I Length = 279 Score = 256 bits (655), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 124/204 (60%), Positives = 150/204 (73%), Gaps = 4/204 (1%) Query: 11 ASHSPESSPLGKSSQYPTHYDPSLLFPIPRAPKRAELQISGTLPFFGVDLWTAYEISWLN 70 +S + SPLG+S+ YPT YDPSLL+PI R P R +L I+G+LPFFG+D W AYE+SWLN Sbjct: 3 SSDDMKESPLGRSTDYPTRYDPSLLYPIERKPMREKLGITGSLPFFGLDFWNAYELSWLN 62 Query: 71 LRGKPQIAIATFMVPADSPNIIESKSFKLYLNSFNQERLESADQLIDKMRTDLSAAAGAQ 130 LRGKPQ+AI F V ADSPNI+ESKS KLYLNSF Q R++ LI+ +R DLS A G+ Sbjct: 63 LRGKPQVAIMNFTVSADSPNIVESKSLKLYLNSFTQTRMDETGDLINILRNDLSDAFGSP 122 Query: 131 VQVALTEPAQFGQLQFGELSGLLLDRLDVEIEAAASGAHPDGSQLRANSEEATVEETLVS 190 VQV+L +P F ++ EL GLLLDRLD+ AA PD S L++N EE VEETLVS Sbjct: 123 VQVSLKQPGDFPAIKLQELEGLLLDRLDI----AADEYTPDPSFLKSNQEEYPVEETLVS 178 Query: 191 HLLKSNCPVTSQPDWGSVQIQYVG 214 HLLK+NCPVT QPDW S+QI Y G Sbjct: 179 HLLKTNCPVTGQPDWASLQIHYAG 202 >C5AD36.1 C5AD36_BURGB GTP cyclohydrolase family protein Length = 274 Score = 256 bits (655), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 125/202 (61%), Positives = 152/202 (75%), Gaps = 4/202 (1%) Query: 14 SPESSPLGKSSQYPTHYDPSLLFPIPRAPKRAELQISGTLPFFGVDLWTAYEISWLNLRG 73 +PE SPLGK++ Y T YD +LLFPIPRA R ++ I TLPFFG D+W AYE+SWL RG Sbjct: 2 TPEHSPLGKAAVYTTDYDAALLFPIPRAAAREQIGIGATLPFFGTDIWNAYELSWLTPRG 61 Query: 74 KPQIAIATFMVPADSPNIIESKSFKLYLNSFNQERLESADQLIDKMRTDLSAAAGAQVQV 133 KPQIA+ATF+VPADSPNI+ESKSFKLYL SF Q +SAD + D ++ D+SAA GA V V Sbjct: 62 KPQIAVATFLVPADSPNIVESKSFKLYLGSFAQTAFDSADAVRDTLKRDVSAACGASVAV 121 Query: 134 ALTEPAQFGQLQFGELSGLLLDRLDVEIEAAASGAHPDGSQLRANSEEATVEETLVSHLL 193 L P+ F +L+ EL+GL LDRLD++ + HPD + L A+ +E+ VEETLVS LL Sbjct: 122 QLASPSGFAKLKLEELAGLSLDRLDLDTDV----YHPDPTLLSASHDESPVEETLVSDLL 177 Query: 194 KSNCPVTSQPDWGSVQIQYVGA 215 KSNCPVT QPDWGSVQI YVGA Sbjct: 178 KSNCPVTGQPDWGSVQIHYVGA 199 >A4JHT1.1 QUEF_BURVG NADPH-dependent 7-cyano-7-deazaguanine reductase EC=1.7.1.13 Length = 274 Score = 253 bits (647), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 124/201 (61%), Positives = 148/201 (73%), Gaps = 4/201 (1%) Query: 14 SPESSPLGKSSQYPTHYDPSLLFPIPRAPKRAELQISGTLPFFGVDLWTAYEISWLNLRG 73 +PE SPLGK++ Y YD SLLFPIPRA R +L I+ LPFFG D+W AYE+SWLN RG Sbjct: 2 NPEHSPLGKATVYAAQYDASLLFPIPRAGAREQLGIAAALPFFGTDIWNAYELSWLNARG 61 Query: 74 KPQIAIATFMVPADSPNIIESKSFKLYLNSFNQERLESADQLIDKMRTDLSAAAGAQVQV 133 KPQ+A+ATF VPA+SPNI+ESKSFKLYL SF Q + +S D + D ++ D+SAA GA V V Sbjct: 62 KPQLAVATFYVPAESPNIVESKSFKLYLGSFAQSKFDSVDAVRDVLKRDVSAACGASVSV 121 Query: 134 ALTEPAQFGQLQFGELSGLLLDRLDVEIEAAASGAHPDGSQLRANSEEATVEETLVSHLL 193 L P FG+LQ EL GL LDRLD++ + PD S L A ++EA VEETLVS LL Sbjct: 122 QLVSPHDFGKLQMEELDGLSLDRLDLDTDV----YEPDPSLLSAAADEAPVEETLVSDLL 177 Query: 194 KSNCPVTSQPDWGSVQIQYVG 214 +SNCPVT QPDWGSVQI YVG Sbjct: 178 RSNCPVTGQPDWGSVQIHYVG 198 >B1YWG4.1 QUEF_BURA4 NADPH-dependent 7-cyano-7-deazaguanine reductase EC=1.7.1.13 Length = 274 Score = 253 bits (647), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 125/201 (62%), Positives = 147/201 (73%), Gaps = 4/201 (1%) Query: 14 SPESSPLGKSSQYPTHYDPSLLFPIPRAPKRAELQISGTLPFFGVDLWTAYEISWLNLRG 73 +PE SPLGK++ Y YD SLLFPIPRA R +L I+ LPFFG D+W AYE+SWLN RG Sbjct: 2 NPEHSPLGKATVYAAQYDASLLFPIPRAGAREQLGITSALPFFGTDIWNAYELSWLNARG 61 Query: 74 KPQIAIATFMVPADSPNIIESKSFKLYLNSFNQERLESADQLIDKMRTDLSAAAGAQVQV 133 KPQ+A+ATF VPA+SPNI+ESKSFKLYL SF Q + +S D + D ++ D+SAA GA V V Sbjct: 62 KPQLAVATFYVPAESPNIVESKSFKLYLGSFAQSKFDSLDAVRDTLKRDVSAACGASVSV 121 Query: 134 ALTEPAQFGQLQFGELSGLLLDRLDVEIEAAASGAHPDGSQLRANSEEATVEETLVSHLL 193 L P FG+LQ EL GL LDRLD++ + PD S L A EEA VEETLVS LL Sbjct: 122 QLVSPHDFGKLQMEELDGLSLDRLDLDTDV----YEPDPSLLSAAQEEAPVEETLVSDLL 177 Query: 194 KSNCPVTSQPDWGSVQIQYVG 214 +SNCPVT QPDWGSVQI YVG Sbjct: 178 RSNCPVTGQPDWGSVQIHYVG 198 >C5NFY3.1 C5NFY3_BURMA NADPH-dependent 7-cyano-7-deazaguanine reductase EC=1.7.1.- Length = 274 Score = 253 bits (646), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 127/202 (62%), Positives = 148/202 (73%), Gaps = 4/202 (1%) Query: 14 SPESSPLGKSSQYPTHYDPSLLFPIPRAPKRAELQISGTLPFFGVDLWTAYEISWLNLRG 73 +PE SPLGK++ Y YD SLLFPIPRA R ++ I LPFFG D+W AYE+SWLN RG Sbjct: 2 NPEHSPLGKATVYANQYDASLLFPIPRAGAREQIGIGAPLPFFGTDIWNAYELSWLNARG 61 Query: 74 KPQIAIATFMVPADSPNIIESKSFKLYLNSFNQERLESADQLIDKMRTDLSAAAGAQVQV 133 KPQIAIATF VPA+SPNI+ESKSFKLYL SF Q ESAD + D ++ D+SAA GA V V Sbjct: 62 KPQIAIATFYVPAESPNIVESKSFKLYLGSFAQTAFESADAVRDALKRDVSAACGASVTV 121 Query: 134 ALTEPAQFGQLQFGELSGLLLDRLDVEIEAAASGAHPDGSQLRANSEEATVEETLVSHLL 193 L PA+F +LQ EL GL LDRLD++ + D S L A+ +EA VEETLV+ LL Sbjct: 122 RLATPAEFRKLQMDELDGLSLDRLDLDAHVYET----DPSFLTASHDEAPVEETLVTDLL 177 Query: 194 KSNCPVTSQPDWGSVQIQYVGA 215 KSNCPVT QPDWGSVQI YVGA Sbjct: 178 KSNCPVTGQPDWGSVQIHYVGA 199 >C4ASW9.1 C4ASW9_BURMA PreQ(1) synthase EC=1.7.1.13 Length = 274 Score = 253 bits (646), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 127/202 (62%), Positives = 148/202 (73%), Gaps = 4/202 (1%) Query: 14 SPESSPLGKSSQYPTHYDPSLLFPIPRAPKRAELQISGTLPFFGVDLWTAYEISWLNLRG 73 +PE SPLGK++ Y YD SLLFPIPRA R ++ I LPFFG D+W AYE+SWLN RG Sbjct: 2 NPEHSPLGKATVYANQYDASLLFPIPRAGAREQIGIGAPLPFFGTDIWNAYELSWLNARG 61 Query: 74 KPQIAIATFMVPADSPNIIESKSFKLYLNSFNQERLESADQLIDKMRTDLSAAAGAQVQV 133 KPQIAIATF VPA+SPNI+ESKSFKLYL SF Q ESAD + D ++ D+SAA GA V V Sbjct: 62 KPQIAIATFYVPAESPNIVESKSFKLYLGSFAQTAFESADAVRDALKRDVSAACGASVTV 121 Query: 134 ALTEPAQFGQLQFGELSGLLLDRLDVEIEAAASGAHPDGSQLRANSEEATVEETLVSHLL 193 L PA+F +LQ EL GL LDRLD++ + D S L A+ +EA VEETLV+ LL Sbjct: 122 RLATPAEFRKLQMDELDGLSLDRLDLDAHVYET----DPSFLTASHDEAPVEETLVTDLL 177 Query: 194 KSNCPVTSQPDWGSVQIQYVGA 215 KSNCPVT QPDWGSVQI YVGA Sbjct: 178 KSNCPVTGQPDWGSVQIHYVGA 199 >B7CJ70.1 B7CJ70_BURPS NADPH-dependent 7-cyano-7-deazaguanine reductase EC=1.7.1.- Length = 274 Score = 253 bits (646), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 127/202 (62%), Positives = 148/202 (73%), Gaps = 4/202 (1%) Query: 14 SPESSPLGKSSQYPTHYDPSLLFPIPRAPKRAELQISGTLPFFGVDLWTAYEISWLNLRG 73 +PE SPLGK++ Y YD SLLFPIPRA R ++ I LPFFG D+W AYE+SWLN RG Sbjct: 2 NPEHSPLGKATVYANQYDASLLFPIPRAGAREQIGIGAPLPFFGTDIWNAYELSWLNARG 61 Query: 74 KPQIAIATFMVPADSPNIIESKSFKLYLNSFNQERLESADQLIDKMRTDLSAAAGAQVQV 133 KPQIAIATF VPA+SPNI+ESKSFKLYL SF Q ESAD + D ++ D+SAA GA V V Sbjct: 62 KPQIAIATFYVPAESPNIVESKSFKLYLGSFAQTAFESADAVRDALKRDVSAACGASVTV 121 Query: 134 ALTEPAQFGQLQFGELSGLLLDRLDVEIEAAASGAHPDGSQLRANSEEATVEETLVSHLL 193 L PA+F +LQ EL GL LDRLD++ + D S L A+ +EA VEETLV+ LL Sbjct: 122 RLATPAEFRKLQMDELDGLSLDRLDLDAHVYET----DPSFLTASHDEAPVEETLVTDLL 177 Query: 194 KSNCPVTSQPDWGSVQIQYVGA 215 KSNCPVT QPDWGSVQI YVGA Sbjct: 178 KSNCPVTGQPDWGSVQIHYVGA 199