BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0238.p (475 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J0I5.1 D8J0I5_HERSS Cobalt/zinc/cadmium resistance two compone... 955 0.0 Q7WET9.1 Q7WET9_BORBR Sensor kinase protein 540 e-151 D5WH15.1 D5WH15_BURSC Multi-sensor signal transduction histidine... 508 e-142 B5WEC6.1 B5WEC6_9BURK Heavy metal sensor signal transduction his... 499 e-139 D5NHY9.1 D5NHY9_9BURK Multi-sensor signal transduction histidine... 494 e-137 Q13NX1.1 Q13NX1_BURXL Heavy metal sensor signal transduction his... 490 e-136 B2TC78.1 B2TC78_BURPP Heavy metal sensor signal transduction his... 487 e-135 D1RNL5.1 D1RNL5_SEROD Heavy metal sensor signal transduction his... 419 e-115 A8GBW3.1 A8GBW3_SERP5 Heavy metal sensor signal transduction his... 416 e-114 Q02FD2.1 Q02FD2_PSEAB Putative two-component sensor 407 e-111 >D8J0I5.1 D8J0I5_HERSS Cobalt/zinc/cadmium resistance two component transmembrane sensor histidine kinase protein EC=2.7.3.- Length = 475 Score = 955 bits (2469), Expect = 0.0, Method: Compositional matrix adjust. Identities = 471/475 (99%), Positives = 474/475 (99%) Query: 1 MSPPTPAVGGWTLTTRVTALFALMTSLVVTGLGFYLDRSAGQALSQRADQALIGRVEHFR 60 MSPPTPAVGGWTLTTRVTALFALMTSLVVTGLGFYLDRSAGQALSQRADQALIGRVEHFR Sbjct: 1 MSPPTPAVGGWTLTTRVTALFALMTSLVVTGLGFYLDRSAGQALSQRADQALIGRVEHFR 60 Query: 61 NLMHDLYNVEQMEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHLVPPAMTPLPVGS 120 NLMHDLYNVEQMEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHLVPPAMTPLPVGS Sbjct: 61 NLMHDLYNVEQMEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHLVPPAMTPLPVGS 120 Query: 121 PVSSASLRTSQRADGVRVRWVSALADVGKGGDTVEIVAAYVMVQEARMMRSYRWRIAGAA 180 PVSSASLRTSQRADGVRVRWVSALADVGKGGDTVEIVAAYVMVQEARMMRSYRWRIAGAA Sbjct: 121 PVSSASLRTSQRADGVRVRWVSALADVGKGGDTVEIVAAYVMVQEARMMRSYRWRIAGAA 180 Query: 181 AAAVVMTALLGFLLLRRGLQPLEAMSQRAAQITPDHLSARLDQEGMPAELRRVALSFNAM 240 AAAVV+TALLGFLLLRRGLQPLEAMSQRAAQITPDHLSARLDQEGMPAELRRVALSFNAM Sbjct: 181 AAAVVLTALLGFLLLRRGLQPLEAMSQRAAQITPDHLSARLDQEGMPAELRRVALSFNAM 240 Query: 241 LDRLEAGYAHLAQFSGDLAHEIRTPINVLMGQSQVALGQRRSPEEYEQVLESNVEELQRL 300 LDRLEAGYAHLAQFSGDLAHEIRTPINVLMGQSQVALGQRRSPEEYEQVLESNVEELQRL Sbjct: 241 LDRLEAGYAHLAQFSGDLAHEIRTPINVLMGQSQVALGQRRSPEEYEQVLESNVEELQRL 300 Query: 301 SRIVENILFLAQADHAALAVERSALDLAEELGRITDYFEGIADERGMRFDVQAAGQCQAN 360 SRIVENILFLAQADHAALAVER+ALDLAEELGRITDYFEGIADERGMRFDVQAAGQCQAN Sbjct: 301 SRIVENILFLAQADHAALAVERNALDLAEELGRITDYFEGIADERGMRFDVQAAGQCQAN 360 Query: 361 LIMWRRAVSNLVINAVRYGQAESTIRILAESDGEGSRIMVENRSEDVTAQAMARMFDRFY 420 LIMWRR VSNLVINAVRYG+AESTIRILAESDGEGSRIMVENRSEDVTAQAMARMFDRFY Sbjct: 361 LIMWRRVVSNLVINAVRYGRAESTIRILAESDGEGSRIMVENRSEDVTAQAMARMFDRFY 420 Query: 421 RGDRSRSAFTESNGLGLAIVKAIMALHGGTAAVECPAPGWIRFSLRFPSAAAVPS 475 RGDRSRSAFTESNGLGLAIVKAIMALHGGTAAVECPAPGWIRFSLRFPSAAAVPS Sbjct: 421 RGDRSRSAFTESNGLGLAIVKAIMALHGGTAAVECPAPGWIRFSLRFPSAAAVPS 475 >Q7WET9.1 Q7WET9_BORBR Sensor kinase protein Length = 471 Score = 540 bits (1391), Expect = e-151, Method: Compositional matrix adjust. Identities = 282/468 (60%), Positives = 351/468 (75%), Gaps = 3/468 (0%) Query: 11 WTL---TTRVTALFALMTSLVVTGLGFYLDRSAGQALSQRADQALIGRVEHFRNLMHDLY 67 WTL T R FA+++ LVV+GLG YL SA QAL RAD L+GRVE FRN++HDLY Sbjct: 4 WTLDSLTVRTALSFAVVSCLVVSGLGLYLYSSARQALETRADYTLVGRVERFRNMLHDLY 63 Query: 68 NVEQMEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHLVPPAMTPLPVGSPVSSASL 127 N+ QMEQRPALFESM+GNE+DVRIFRR GEAPFI NPD + PP MTP+PVG ++ SL Sbjct: 64 NIRQMEQRPALFESMLGNERDVRIFRRLGEAPFIAVNPDGMAPPPMTPVPVGRDITIESL 123 Query: 128 RTSQRADGVRVRWVSALADVGKGGDTVEIVAAYVMVQEARMMRSYRWRIAGAAAAAVVMT 187 + +R DGVRVRWVSALA++G+ G TVE+ AAYVM QE+ M+ +Y R+ A ++T Sbjct: 124 HSGERPDGVRVRWVSALAEIGEDGGTVEVTAAYVMKQESNMLSAYLLRVVVAIVLTTLLT 183 Query: 188 ALLGFLLLRRGLQPLEAMSQRAAQITPDHLSARLDQEGMPAELRRVALSFNAMLDRLEAG 247 AL+G+ LL RG +PL AMS RA +I+P +L+ARL + PAELR +A FNAMLDRL+AG Sbjct: 184 ALIGYALLVRGFRPLAAMSARATEISPANLAARLPERDAPAELRGLARQFNAMLDRLQAG 243 Query: 248 YAHLAQFSGDLAHEIRTPINVLMGQSQVALGQRRSPEEYEQVLESNVEELQRLSRIVENI 307 Y HL+QFS DLAHEIRTPINVLMGQ+QVAL Q R +EYE +LESN+EEL RL+ IVENI Sbjct: 244 YEHLSQFSADLAHEIRTPINVLMGQTQVALRQPRGADEYELLLESNLEELARLAHIVENI 303 Query: 308 LFLAQADHAALAVERSALDLAEELGRITDYFEGIADERGMRFDVQAAGQCQANLIMWRRA 367 LFL++A+H AVE + L + EL +I +YFEG A ERGMRF ++A+GQC+AN IMWRRA Sbjct: 304 LFLSRANHDGAAVEYAWLAQSAELAKIAEYFEGPAQERGMRFAIEASGQCRANPIMWRRA 363 Query: 368 VSNLVINAVRYGQAESTIRILAESDGEGSRIMVENRSEDVTAQAMARMFDRFYRGDRSRS 427 V+NLV+NAVRYG +S I + A +D G+ I+VEN V+ + RMF RFYR D+SR+ Sbjct: 364 VNNLVVNAVRYGHPDSCILLRAGADANGATIVVENMGAPVSQEEADRMFGRFYRSDKSRT 423 Query: 428 AFTESNGLGLAIVKAIMALHGGTAAVECPAPGWIRFSLRFPSAAAVPS 475 A TESNGLGLAIV AIM +HGG+A+ G IRF+LRFP A P+ Sbjct: 424 ASTESNGLGLAIVSAIMRMHGGSASATALDDGRIRFTLRFPPGPAAPA 471 >D5WH15.1 D5WH15_BURSC Multi-sensor signal transduction histidine kinase Length = 466 Score = 508 bits (1309), Expect = e-142, Method: Compositional matrix adjust. Identities = 253/463 (54%), Positives = 323/463 (69%), Gaps = 3/463 (0%) Query: 11 WT---LTTRVTALFALMTSLVVTGLGFYLDRSAGQALSQRADQALIGRVEHFRNLMHDLY 67 WT L R T LFAL+ V+ LG Y SA AL +RAD L GRVEHF ++HDLY Sbjct: 4 WTERSLIARTTLLFALIACAVIGSLGAYFYHSAEVALQRRADVVLSGRVEHFSRIVHDLY 63 Query: 68 NVEQMEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHLVPPAMTPLPVGSPVSSASL 127 +V ++++RP LFE+M+G E+DV IFRR GEAPF+ NP L P + +P G+P + + Sbjct: 64 SVSELKKRPLLFETMLGAEEDVLIFRRPGEAPFVDVNPGGLAVPDLPVMPAGNPPRATDV 123 Query: 128 RTSQRADGVRVRWVSALADVGKGGDTVEIVAAYVMVQEARMMRSYRWRIAGAAAAAVVMT 187 R ++ DGV V W A A + G VE++A + M E RM+ YR RI A ++ Sbjct: 124 RRTRLPDGVPVHWAIATATAREDGAEVEVIAGHPMTHEMRMLAEYRNRIVLATLTGMLAA 183 Query: 188 ALLGFLLLRRGLQPLEAMSQRAAQITPDHLSARLDQEGMPAELRRVALSFNAMLDRLEAG 247 LL + +LRR L+P+ ++ RAAQI+P +L+ RLD E P ELR++ +FNAMLDRL G Sbjct: 184 TLLAYCVLRRALRPVREIAARAAQISPTNLAVRLDDEAAPVELRQLTHAFNAMLDRLADG 243 Query: 248 YAHLAQFSGDLAHEIRTPINVLMGQSQVALGQRRSPEEYEQVLESNVEELQRLSRIVENI 307 Y L QFS DLAHEIRTP+ L+GQ+QVAL Q R P+EY+Q+LESN+EEL RLS I ENI Sbjct: 244 YQRLQQFSADLAHEIRTPVGALVGQTQVALAQPREPDEYQQLLESNLEELNRLSHIAENI 303 Query: 308 LFLAQADHAALAVERSALDLAEELGRITDYFEGIADERGMRFDVQAAGQCQANLIMWRRA 367 LFLA ADHAAL++ER +DL EL RI DYFEG+ADERGMRF+V AAG AN ++ RRA Sbjct: 304 LFLAHADHAALSIERQPVDLHGELVRIADYFEGLADERGMRFEVDAAGIASANPMLCRRA 363 Query: 368 VSNLVINAVRYGQAESTIRILAESDGEGSRIMVENRSEDVTAQAMARMFDRFYRGDRSRS 427 ++NLV+NAVRYG ++ +R+ D G+ + VEN E + A + R+FDRFYRGD +RS Sbjct: 364 INNLVVNAVRYGSGDTIVRLRGAQDQAGALVTVENEGEPIPAAQLDRLFDRFYRGDAARS 423 Query: 428 AFTESNGLGLAIVKAIMALHGGTAAVECPAPGWIRFSLRFPSA 470 AFTESNGLGLAIVKAIM LHGG+A V CP PG +RF LRFP+A Sbjct: 424 AFTESNGLGLAIVKAIMHLHGGSARVVCPLPGVVRFELRFPAA 466 >B5WEC6.1 B5WEC6_9BURK Heavy metal sensor signal transduction histidine kinase Length = 466 Score = 499 bits (1285), Expect = e-139, Method: Compositional matrix adjust. Identities = 250/463 (53%), Positives = 320/463 (69%), Gaps = 3/463 (0%) Query: 11 WT---LTTRVTALFALMTSLVVTGLGFYLDRSAGQALSQRADQALIGRVEHFRNLMHDLY 67 WT L R T LFAL+ +V+ LG Y SA +L +RAD L GRV HF ++HDLY Sbjct: 4 WTERSLIARTTLLFALIACVVIGSLGAYFYHSAEVSLQRRADVVLSGRVGHFSRIVHDLY 63 Query: 68 NVEQMEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHLVPPAMTPLPVGSPVSSASL 127 +V ++++RP LFE+M+G E+DV IFRR GEAPF+ NP L P + G+ +A + Sbjct: 64 SVSELKKRPLLFETMLGAEEDVLIFRRPGEAPFVDVNPARLAVPDLQDAAAGNLPRAADI 123 Query: 128 RTSQRADGVRVRWVSALADVGKGGDTVEIVAAYVMVQEARMMRSYRWRIAGAAAAAVVMT 187 R ++ DGV V W A A + G VE++A + M QE RM+ +YR RI A ++ Sbjct: 124 RQTRLPDGVPVHWAIATARSREDGTEVEVIAGHPMTQEMRMLAAYRNRIVLATLTGMLAA 183 Query: 188 ALLGFLLLRRGLQPLEAMSQRAAQITPDHLSARLDQEGMPAELRRVALSFNAMLDRLEAG 247 LL + +LRR L+P+ ++ RAAQI+P +L+ RLD E P ELR++ +FNAMLDRL G Sbjct: 184 TLLAYFVLRRALRPVREIATRAAQISPANLAVRLDDEAAPVELRQLTQAFNAMLDRLADG 243 Query: 248 YAHLAQFSGDLAHEIRTPINVLMGQSQVALGQRRSPEEYEQVLESNVEELQRLSRIVENI 307 Y L QFS DLAHEIRTP+ L+GQ+QVAL Q R P+EY+Q+LESN+EEL RLS I ENI Sbjct: 244 YQRLQQFSADLAHEIRTPVGALVGQTQVALAQPREPDEYQQLLESNLEELSRLSHIAENI 303 Query: 308 LFLAQADHAALAVERSALDLAEELGRITDYFEGIADERGMRFDVQAAGQCQANLIMWRRA 367 LFLA ADHAAL++ER +DL EL RI DYFEG+ADERGMRF+V A G AN ++WRRA Sbjct: 304 LFLAHADHAALSIERQPVDLQGELVRIADYFEGLADERGMRFEVDATGVVSANPMLWRRA 363 Query: 368 VSNLVINAVRYGQAESTIRILAESDGEGSRIMVENRSEDVTAQAMARMFDRFYRGDRSRS 427 ++NLV NAVRYG +S +R+ D G+ + VEN + + + R+FDRFYRGD +RS Sbjct: 364 INNLVANAVRYGAGDSIVRLRGAQDEAGALVTVENEGDPIPTAQLDRLFDRFYRGDAARS 423 Query: 428 AFTESNGLGLAIVKAIMALHGGTAAVECPAPGWIRFSLRFPSA 470 AFTESNGLGLAIVKAIM LHGG+A V CP PG +RF LRFP A Sbjct: 424 AFTESNGLGLAIVKAIMHLHGGSAQVVCPLPGVVRFELRFPGA 466 >D5NHY9.1 D5NHY9_9BURK Multi-sensor signal transduction histidine kinase Length = 466 Score = 494 bits (1272), Expect = e-137, Method: Compositional matrix adjust. Identities = 248/459 (54%), Positives = 319/459 (69%) Query: 10 GWTLTTRVTALFALMTSLVVTGLGFYLDRSAGQALSQRADQALIGRVEHFRNLMHDLYNV 69 G +LT R T LFA + +V+ LG Y RSA +L RAD L RVEHF ++HDLY+V Sbjct: 6 GRSLTARTTVLFASIACVVIGTLGAYFYRSAELSLQLRADLVLTARVEHFSRIVHDLYSV 65 Query: 70 EQMEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHLVPPAMTPLPVGSPVSSASLRT 129 +++ RP LFE+M+G EQDV +FRR GEAPFI NP+ + PA+ G + A +R Sbjct: 66 SELKNRPLLFETMLGAEQDVLLFRRPGEAPFIDVNPEGVAVPALQAGEAGRLPTIADIRQ 125 Query: 130 SQRADGVRVRWVSALADVGKGGDTVEIVAAYVMVQEARMMRSYRWRIAGAAAAAVVMTAL 189 ++ ADGV V W A A + G VE++A + M QE RM+ +YR RI A ++ L Sbjct: 126 TRLADGVPVHWAIATATAREDGTEVEVIAGHPMTQEVRMLAAYRNRIVLATLIGMLAATL 185 Query: 190 LGFLLLRRGLQPLEAMSQRAAQITPDHLSARLDQEGMPAELRRVALSFNAMLDRLEAGYA 249 L + +LRR L+P+ ++ RAAQI+P LS RLD E P ELR++ +FNAMLDRL GY Sbjct: 186 LAYYVLRRALRPVREIATRAAQISPASLSVRLDSEAAPLELRQLTHAFNAMLDRLADGYQ 245 Query: 250 HLAQFSGDLAHEIRTPINVLMGQSQVALGQRRSPEEYEQVLESNVEELQRLSRIVENILF 309 L+QFS DLAHEIRTP+ L+GQ+QV L + R PEEY+Q+LESN+EEL RLS I ENILF Sbjct: 246 RLSQFSADLAHEIRTPVGALIGQTQVTLARTREPEEYQQLLESNLEELSRLSHIAENILF 305 Query: 310 LAQADHAALAVERSALDLAEELGRITDYFEGIADERGMRFDVQAAGQCQANLIMWRRAVS 369 LA ADHAAL+V+R +DL EL RI DYFEG ADERGMRF V+A G N ++ RRA++ Sbjct: 306 LAHADHAALSVDREPVDLRGELVRIADYFEGPADERGMRFVVEAEGVASVNPMLCRRAIN 365 Query: 370 NLVINAVRYGQAESTIRILAESDGEGSRIMVENRSEDVTAQAMARMFDRFYRGDRSRSAF 429 NLV+NAVRYG +++ +R+ D G+ ++VEN + + + R+FDRFYR D +RSAF Sbjct: 366 NLVVNAVRYGASDTVVRLRGTQDEGGATVVVENDGAPIPEEQLGRLFDRFYRADAARSAF 425 Query: 430 TESNGLGLAIVKAIMALHGGTAAVECPAPGWIRFSLRFP 468 TES+GLGLAIVKAIM LHGGTA V CPAPG +RF LRFP Sbjct: 426 TESSGLGLAIVKAIMHLHGGTARVVCPAPGVVRFELRFP 464 >Q13NX1.1 Q13NX1_BURXL Heavy metal sensor signal transduction histidine kinases (STHK) EC=2.7.3.- Length = 466 Score = 490 bits (1262), Expect = e-136, Method: Compositional matrix adjust. Identities = 247/459 (53%), Positives = 318/459 (69%) Query: 10 GWTLTTRVTALFALMTSLVVTGLGFYLDRSAGQALSQRADQALIGRVEHFRNLMHDLYNV 69 G +LT R T LFA + +V+ LG Y RSA +L +RAD L RVEHF ++ DLY+V Sbjct: 6 GRSLTARTTVLFASIACVVIGTLGAYFYRSAELSLERRADVVLAARVEHFSRIVRDLYSV 65 Query: 70 EQMEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHLVPPAMTPLPVGSPVSSASLRT 129 +++ RP LFE+M+G EQDV +FRR GEAPFI NP + PA+ G + A +R Sbjct: 66 SELKNRPLLFETMLGAEQDVLLFRRPGEAPFIDVNPAGVAVPALQAGEAGRLPTFADIRQ 125 Query: 130 SQRADGVRVRWVSALADVGKGGDTVEIVAAYVMVQEARMMRSYRWRIAGAAAAAVVMTAL 189 ++ ADGV V W A A + G VE++A + M QE RM+ +YR RI A ++ L Sbjct: 126 TRLADGVPVHWAMATARAREDGTEVEVIAGHPMTQEVRMLAAYRNRIVLATLIGMLAATL 185 Query: 190 LGFLLLRRGLQPLEAMSQRAAQITPDHLSARLDQEGMPAELRRVALSFNAMLDRLEAGYA 249 L + +LRR L+P+ ++ RAAQI+P LS RLD P ELR++ +FNAMLDRL GY Sbjct: 186 LAYYVLRRALRPVREIATRAAQISPASLSVRLDSAAAPLELRQLTHAFNAMLDRLADGYQ 245 Query: 250 HLAQFSGDLAHEIRTPINVLMGQSQVALGQRRSPEEYEQVLESNVEELQRLSRIVENILF 309 L+QFS DLAHEIRTP+ L+GQ+QV L + R PEEY+Q+LESN+EEL RLS I ENILF Sbjct: 246 RLSQFSADLAHEIRTPVGALIGQTQVTLARTREPEEYQQLLESNLEELSRLSHIAENILF 305 Query: 310 LAQADHAALAVERSALDLAEELGRITDYFEGIADERGMRFDVQAAGQCQANLIMWRRAVS 369 LA ADHAAL+V+R +DL EL RI DYFEG ADERGMRF V+A G N ++ RRA++ Sbjct: 306 LAHADHAALSVDREPVDLRGELVRIADYFEGPADERGMRFAVEAEGVASVNPMLCRRAIN 365 Query: 370 NLVINAVRYGQAESTIRILAESDGEGSRIMVENRSEDVTAQAMARMFDRFYRGDRSRSAF 429 NLV+NAVRYG +++ +R+ D EG+ ++VEN + + + R+FDRFYR D +RSAF Sbjct: 366 NLVVNAVRYGASDTVVRLRGTQDEEGATVVVENDGAPIPEEQLGRLFDRFYRADAARSAF 425 Query: 430 TESNGLGLAIVKAIMALHGGTAAVECPAPGWIRFSLRFP 468 TES+GLGLAIVKAIM LHGGTA V CPAPG +RF LRFP Sbjct: 426 TESSGLGLAIVKAIMHLHGGTARVVCPAPGVVRFELRFP 464 >B2TC78.1 B2TC78_BURPP Heavy metal sensor signal transduction histidine kinase Length = 466 Score = 487 bits (1254), Expect = e-135, Method: Compositional matrix adjust. Identities = 247/461 (53%), Positives = 320/461 (69%) Query: 10 GWTLTTRVTALFALMTSLVVTGLGFYLDRSAGQALSQRADQALIGRVEHFRNLMHDLYNV 69 G +LT R T LFA + +V+ LG Y SA +L +RAD L RVEHF ++ DLY+V Sbjct: 6 GRSLTARTTVLFASIACVVIGTLGAYFYHSAEVSLQRRADVVLTARVEHFSRIVRDLYSV 65 Query: 70 EQMEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHLVPPAMTPLPVGSPVSSASLRT 129 +++ RP LFE+M+G EQDV +FRR GEAPFI NP + PA+ G + A +R Sbjct: 66 GELKSRPLLFETMLGAEQDVLLFRRPGEAPFIDVNPAGVAVPALQAGVEGRLPTFADVRQ 125 Query: 130 SQRADGVRVRWVSALADVGKGGDTVEIVAAYVMVQEARMMRSYRWRIAGAAAAAVVMTAL 189 ++ A+GV V W A A + G VE++A + M +E RM+ +YR RI A ++ L Sbjct: 126 TRLANGVPVHWAIATAKAREDGTEVEVIAGHPMTEEVRMLAAYRDRIVLATLIGMLAATL 185 Query: 190 LGFLLLRRGLQPLEAMSQRAAQITPDHLSARLDQEGMPAELRRVALSFNAMLDRLEAGYA 249 L + +LRR L+P+ ++ RAAQI+P LS RLD E P ELR++ +FNAML+RL GY Sbjct: 186 LAWYVLRRALRPVREIATRAAQISPTSLSVRLDSEAAPLELRQLTHAFNAMLERLADGYQ 245 Query: 250 HLAQFSGDLAHEIRTPINVLMGQSQVALGQRRSPEEYEQVLESNVEELQRLSRIVENILF 309 L+QFS DLAHEIRTP+ L+GQ+QV L + R P+EY+QVLESN+EEL RLS I ENILF Sbjct: 246 RLSQFSADLAHEIRTPVGALIGQTQVTLARIREPDEYQQVLESNLEELSRLSHIAENILF 305 Query: 310 LAQADHAALAVERSALDLAEELGRITDYFEGIADERGMRFDVQAAGQCQANLIMWRRAVS 369 LA ADHAAL+VER +DL EEL RI DYFEG ADERGMRF V+A G AN ++ RRA++ Sbjct: 306 LAHADHAALSVEREPVDLREELVRIADYFEGPADERGMRFVVEATGVASANPMLCRRAIN 365 Query: 370 NLVINAVRYGQAESTIRILAESDGEGSRIMVENRSEDVTAQAMARMFDRFYRGDRSRSAF 429 NLV+NAVRYG +++ +R+ D G+ ++VEN + + + R+FDRFYR D +RSAF Sbjct: 366 NLVVNAVRYGASDTVVRLRGTQDEAGATVVVENDGAPIPEEQLGRLFDRFYRADTARSAF 425 Query: 430 TESNGLGLAIVKAIMALHGGTAAVECPAPGWIRFSLRFPSA 470 TES+GLGLAIVKAIM LHGGTA V CPAPG +RF LRFP A Sbjct: 426 TESSGLGLAIVKAIMHLHGGTARVVCPAPGVVRFELRFPGA 466 >D1RNL5.1 D1RNL5_SEROD Heavy metal sensor signal transduction histidine kinase Length = 474 Score = 419 bits (1076), Expect = e-115, Method: Compositional matrix adjust. Identities = 222/463 (47%), Positives = 312/463 (67%), Gaps = 5/463 (1%) Query: 12 TLTTRVTALFALMTSLVVTGLGFYLDRSAGQALSQRADQALIGRVEHFRNLMHDLYNVEQ 71 +LT R LFAL+ +LVV+G G+YL + Q ++ R+D + GRVE+FR+L+ + +++ Sbjct: 12 SLTIRSAMLFALVAALVVSGAGWYLYGAMRQEMTTRSDFQVTGRVEYFRHLLSQRFPLDR 71 Query: 72 MEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHLVPPAMTPLPVGSPVSSASLRTSQ 131 + LFE+M+GNEQDV IF++ G+ P I NP L P +TP PV +P +++ + + Sbjct: 72 LVANTGLFENMLGNEQDVLIFQQPGQKPLINVNPARLTLPPITPTPVDAPQLLSAVSSGE 131 Query: 132 RADGVRVRWVSALADVGKGGDTVEIVAAYVMVQEARMMRSYRWRIAGAAAAAVVMTALLG 191 A GV +R SAL + G + ++I AA+VMV E +M+ Y WRI A A A ++ ALLG Sbjct: 132 TAQGVPLRVASALVRLDDG-NLLQISAAHVMVNEQKMLARYLWRIVAAVAVAFLLIALLG 190 Query: 192 FLLLRRGLQPLEAMSQRAAQITPDHLSARLDQEGMPAELRRVALSFNAMLDRLEAGYAHL 251 + ++RRGLQPL M+ +AA ITP+ LS RL ++G P ELR++ SFNAMLDRL GY L Sbjct: 191 YWVMRRGLQPLWRMAAQAAVITPNTLSTRLSEQGAPKELRQLTRSFNAMLDRLNDGYQRL 250 Query: 252 AQFSGDLAHEIRTPINVLMGQSQVALGQRRSPEEYEQVLESNVEELQRLSRIVENILFLA 311 QFS DLAHEIRTP+ LMG QVAL Q RS EEYE +L +N++EL+R+SR+VENILFLA Sbjct: 251 TQFSADLAHEIRTPVGALMGHCQVALYQPRSVEEYETLLSNNMDELERISRMVENILFLA 310 Query: 312 QADHAALAVERSALDLAEELGRITDYFEGIADERGMRFDVQAAGQCQANLIMWRRAVSNL 371 +A A + S +D+A+EL R+ DYFEG+A+ERG+ + GQ A+ ++++RA+SNL Sbjct: 311 RAGEAQAVLNCSRMDIAQELQRVADYFEGLAEERGITLVCRGEGQLMADAMLFQRALSNL 370 Query: 372 VINAVRYGQAESTIRILAESDGEGSRIM-VENRSEDVTAQAMARMFDRFYRGDRSRSAFT 430 V NAVRY S IR+ A S +G ++ V N+ ++ + ++FDRFYR D +RSA + Sbjct: 371 VANAVRYADENSQIRLQALSQPKGRVVIQVVNQGRPISPAHLDKLFDRFYRADAARSAGS 430 Query: 431 ESNGLGLAIVKAIMALHGGTAAVECPA---PGWIRFSLRFPSA 470 ++GLGL+IV+AIM LHGG EC A I FSL FP A Sbjct: 431 HASGLGLSIVRAIMTLHGGEVRAECIAGEPAARITFSLIFPQA 473 >A8GBW3.1 A8GBW3_SERP5 Heavy metal sensor signal transduction histidine kinase Length = 474 Score = 416 bits (1070), Expect = e-114, Method: Compositional matrix adjust. Identities = 222/464 (47%), Positives = 308/464 (66%), Gaps = 7/464 (1%) Query: 12 TLTTRVTALFALMTSLVVTGLGFYLDRSAGQALSQRADQALIGRVEHFRNLMHDLYNVEQ 71 +LT R LFAL+ +LVV+G G+YL + Q ++ R+D + GRVE++RNL+ + +E+ Sbjct: 12 SLTLRSAMLFALVAALVVSGAGWYLYDAMRQEMTLRSDLQVTGRVEYYRNLLSRRFPLER 71 Query: 72 MEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHLVPPAMTPLPVGSPVSSASLRTSQ 131 + LFE+M+GNEQDV IF++ G+ P I NP L P M P PVG+P +++++ Q Sbjct: 72 LMANTGLFENMLGNEQDVLIFQQPGQKPLINVNPARLSLPPMIPTPVGTPQRLSAVQSGQ 131 Query: 132 RADGVRVRWVSALADVGKGGDTVEIVAAYVMVQEARMMRSYRWRIAGAAAAAVVMTALLG 191 A GV +R VSAL + + G+ ++I AA+VM E +M+ Y WRI A A V+ ALLG Sbjct: 132 TAQGVPLRAVSALVRL-EDGNLLQISAAHVMFNEQKMLARYLWRIVAAVIVAFVLIALLG 190 Query: 192 FLLLRRGLQPLEAMSQRAAQITPDHLSARLDQEGMPAELRRVALSFNAMLDRLEAGYAHL 251 + ++RRGLQPL M+ +AA ITP+ LS RL ++G P EL+++ SFNAMLDRL GY L Sbjct: 191 YWVMRRGLQPLWRMAAQAAVITPNTLSTRLSEQGAPKELQQLTRSFNAMLDRLNEGYQRL 250 Query: 252 AQFSGDLAHEIRTPINVLMGQSQVALGQRRSPEEYEQVLESNVEELQRLSRIVENILFLA 311 QFS DLAHEIRTP+ LMGQ QVAL Q RS EEYE +L +N++EL+R+SR+VENILFLA Sbjct: 251 TQFSADLAHEIRTPVGALMGQCQVALYQSRSVEEYETLLSNNMDELERISRMVENILFLA 310 Query: 312 QADHAALAVERSALDLAEELGRITDYFEGIADERGMRFDVQAAGQCQANLIMWRRAVSNL 371 +A + S LD+A+EL R+ DYFEG+A+ERG+ GQ A+ ++++RA+SNL Sbjct: 311 RAGEGQAVLNVSRLDMAQELQRVADYFEGLAEERGITLVCAGRGQLLADAMLFQRALSNL 370 Query: 372 VINAVRYGQAESTI--RILAESDGEGSRIMVENRSEDVTAQAMARMFDRFYRGDRSRSAF 429 V NAVRY S I + L + GE + V N+ + + ++FDRFYR D +RS+ Sbjct: 371 VANAVRYADENSQILLQTLTQQTGE-VVVQVVNQGPAIAPAHLDKLFDRFYRADAARSSG 429 Query: 430 TESNGLGLAIVKAIMALHGGTAAVECPA---PGWIRFSLRFPSA 470 + ++GLGLAIV+AIM LHGG C I FSL FP+A Sbjct: 430 SHASGLGLAIVRAIMTLHGGVTRAHCSGGNNSARITFSLIFPAA 473 >Q02FD2.1 Q02FD2_PSEAB Putative two-component sensor Length = 463 Score = 407 bits (1045), Expect = e-111, Method: Compositional matrix adjust. Identities = 217/437 (49%), Positives = 300/437 (68%), Gaps = 2/437 (0%) Query: 33 GFYLDRSAGQALSQRADQALIGRVEHFRNLMHDLYNVEQMEQRPALFESMMGNEQDVRIF 92 GFYL RS +A+ +R+D + GRVEHFRNL+ D + +++ RP LFE+M+GNEQD+ + Sbjct: 27 GFYLYRSVEEAMLRRSDVMVAGRVEHFRNLLRDNLTLAELKARPRLFENMLGNEQDILLL 86 Query: 93 RRQGEAPFIQSNPDHLVPPAMTPLPVGSPVSSASLRTSQRADGVRVRWVSALADVGKGGD 152 + GEAP + NP H P++ + G ++ + + + DGV +R ++A VG G + Sbjct: 87 GQPGEAPIVAVNPRHERLPSLRVVAAGQALNPSVVHAALTHDGVPMRVLAAEVLVG-GRE 145 Query: 153 TVEIVAAYVMVQEARMMRSYRWRIAGAAAAAVVMTALLGFLLLRRGLQPLEAMSQRAAQI 212 ++I AA++++ E RM+ YR R+ A A + TALLG+L+LR GL+PL ++ +AA+I Sbjct: 146 PLQITAAHLLLGETRMLAQYRDRVIAAVLLAFLGTALLGWLVLRHGLRPLRTLAAKAAEI 205 Query: 213 TPDHLSARLDQEGMPAELRRVALSFNAMLDRLEAGYAHLAQFSGDLAHEIRTPINVLMGQ 272 P L RLD PAEL++VA SFNAML+RL+ GY L QFS DLAHEIRTPI LMG Sbjct: 206 HPTSLDTRLDVAAAPAELQQVAQSFNAMLERLDDGYQRLQQFSADLAHEIRTPIGSLMGH 265 Query: 273 SQVALGQRRSPEEYEQVLESNVEELQRLSRIVENILFLAQADHAALAVERSALDLAEELG 332 QVAL Q RS EEY+ ++ SN EEL+R++R+VE+ILFLA+AD AVERS LDL EEL Sbjct: 266 GQVALRQPRSNEEYQALIASNQEELERIARMVESILFLARADDVRAAVERSRLDLGEELR 325 Query: 333 RITDYFEGIADERGMRFDVQAAGQCQANLIMWRRAVSNLVINAVRYGQAESTIRILAESD 392 R +YFEG+A+ERG+ D+Q +GQ +A+ ++RRA+SNL+ NA+RY AES I + Sbjct: 326 RQAEYFEGLAEERGLSLDIQISGQLRADPQLFRRALSNLLANAIRYASAESLIEVRGLRR 385 Query: 393 GEGSRIMVENRSEDVTAQAMARMFDRFYRGDRSRSAFTESNGLGLAIVKAIMALHGGTAA 452 + VEN + + A+ ++R+FDRFYRGD +RS +S+GLGLAIV+AIM LHGG A Sbjct: 386 SGEFLLSVENACDRLPAEPLSRLFDRFYRGDAARSD-AQSSGLGLAIVQAIMRLHGGRAE 444 Query: 453 VECPAPGWIRFSLRFPS 469 PAPG IRF L FP+ Sbjct: 445 ASAPAPGRIRFELAFPA 461