BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0213.p (257 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J0F8.1 D8J0F8_HERSS 2-C-methyl-D-erythritol 4-phosphate cytidy... 493 e-137 A4G6C5.1 A4G6C5_HERAR 2-C-methyl-D-erythritol 4-phosphate cytidy... 273 1e-71 A6SXV2.1 A6SXV2_JANMA 2-C-methyl-D-erythritol 4-phosphate cytidy... 266 2e-69 C3X223.1 C3X223_OXAFO 2-C-methyl-D-erythritol 4-phosphate cytidy... 228 6e-58 C3XA82.1 C3XA82_OXAFO 2-C-methyl-D-erythritol 4-phosphate cytidy... 227 1e-57 Q1H2A3.1 Q1H2A3_METFK 2-C-methyl-D-erythritol 4-phosphate cytidy... 226 2e-57 Q2Y751.1 ISPD_NITMU 2-C-methyl-D-erythritol 4-phosphate cytidyly... 220 2e-55 Q3SK38.1 ISPD_THIDA 2-C-methyl-D-erythritol 4-phosphate cytidyly... 219 2e-55 Q0AFW3.1 ISPD_NITEC 2-C-methyl-D-erythritol 4-phosphate cytidyly... 215 6e-54 Q6SG03.1 Q6SG03_9BACT 2-C-methyl-D-erythritol 4-phosphate cytidy... 213 2e-53 >D8J0F8.1 D8J0F8_HERSS 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase EC=2.7.7.60 Length = 254 Score = 493 bits (1269), Expect = e-137, Method: Compositional matrix adjust. Identities = 250/254 (98%), Positives = 251/254 (98%) Query: 4 MNPSPSTSSLPPAPVSPPARHFALIPAAGVGARMGGQIPKQYLPLAGQPMLLHALQSFAA 63 MNPSPS SSLPPAP SPPARHFALIPAAGVGARMGGQIPKQYLPLAGQPMLLHALQ FAA Sbjct: 1 MNPSPSASSLPPAPASPPARHFALIPAAGVGARMGGQIPKQYLPLAGQPMLLHALQRFAA 60 Query: 64 HARIAHTFVVVSAEDGWIDALMTPALRQRVSILRVGGPTRQDSVFNGLNALREQLADADW 123 HARIAHTFVVVSAEDGWIDALMTPALRQRVSILRVGGPTRQDSVFNGLNALREQLADADW Sbjct: 61 HARIAHTFVVVSAEDGWIDALMTPALRQRVSILRVGGPTRQDSVFNGLNALREQLADADW 120 Query: 124 VLVHDAARPGLDAALIDRLLDALAQDEVGGLLALPVVDTLKRGDGASSPRSQQTVPRAGL 183 VLVHDAARPG+DAALIDRLLDALAQDEVGGLLALPVVDTLKRGDGASSPRSQQTVPRAGL Sbjct: 121 VLVHDAARPGVDAALIDRLLDALAQDEVGGLLALPVVDTLKRGDGASSPRSQQTVPRAGL 180 Query: 184 WAAQTPQMFPYALLHRALRQAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQ 243 WAAQTPQMFPYALLHRALRQAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQ Sbjct: 181 WAAQTPQMFPYALLHRALRQAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQ 240 Query: 244 DAALAEFFLKGPHP 257 DAALAEFFLKGPHP Sbjct: 241 DAALAEFFLKGPHP 254 >A4G6C5.1 A4G6C5_HERAR 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase EC=2.7.7.60 Length = 232 Score = 273 bits (699), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 141/234 (60%), Positives = 172/234 (73%), Gaps = 10/234 (4%) Query: 23 RHFALIPAAGVGARMGGQIPKQYLPLAGQPMLLHALQSFAAHARIAHTFVVVSAEDGWID 82 R+FALIPAAG+GAR+GG PKQY+ +AG+ ML H L +F+ I+HTFVVVSAEDG+I+ Sbjct: 5 RYFALIPAAGIGARIGGSTPKQYVSIAGKAMLRHVLDTFSDTVAISHTFVVVSAEDGYIN 64 Query: 83 ALMT--PALRQRVSILRVGGPTRQDSVFNGLNALREQLADADWVLVHDAARPGLDAALID 140 +M P +++LRVGGPTRQ SV NGL+A RE + D DWVLVHDAARPGL+ +L+D Sbjct: 65 DIMAEPPDHHAGITVLRVGGPTRQLSVLNGLHAAREWIGDDDWVLVHDAARPGLNDSLVD 124 Query: 141 RLLDALAQDEVGGLLALPVVDTLKRGDGASSPRSQQTVPRAGLWAAQTPQMFPYALLHRA 200 +L+ L DEVGGLLA+PVVDTLKR D S R + TV R LWAAQTPQMFPY LL +A Sbjct: 125 KLIQTLKDDEVGGLLAVPVVDTLKRMD--ESGRVENTVAREHLWAAQTPQMFPYGLLKKA 182 Query: 201 LRQAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEFFLKG 254 L QA +TD+A AIE LGL+P+LV G N KVTL +D ALAE +LKG Sbjct: 183 LEQA------AAVTDEAGAIEALGLKPKLVTGHACNFKVTLPEDVALAELYLKG 230 >A6SXV2.1 A6SXV2_JANMA 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase EC=2.7.7.60 Length = 235 Score = 266 bits (680), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 145/238 (60%), Positives = 169/238 (71%), Gaps = 15/238 (6%) Query: 23 RHFALIPAAGVGARMGGQIPKQYLPLAGQPMLLHALQSFAAHARIAHTFVVVSAEDGWID 82 R+FALIPAAGVGARMG +IPKQY+ +AG+PML H L +F I HT+VVVSAEDG+ID Sbjct: 5 RYFALIPAAGVGARMGEKIPKQYVQIAGKPMLRHVLDTFCRADVITHTYVVVSAEDGYID 64 Query: 83 ALMTPALRQ--RVSILRVGGPTRQDSVFNGLNALREQ----LADADWVLVHDAARPGLDA 136 A M AL ++LRVGG TR SV NGL A++EQ + D DWVLVHDAARPGL Sbjct: 65 ATMA-ALHDSSYATVLRVGGATRHQSVLNGLQAMQEQVNEPINDDDWVLVHDAARPGLSI 123 Query: 137 ALIDRLLDALAQDEVGGLLALPVVDTLKRGDGASSPRSQQTVPRAGLWAAQTPQMFPYAL 196 LID+L++ L DEVGGLLA+PVVDTLKR + R QTV R LWAAQTPQMF Y L Sbjct: 124 GLIDKLINILQDDEVGGLLAMPVVDTLKR--AGAEGRVDQTVTRDRLWAAQTPQMFRYGL 181 Query: 197 LHRALRQAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEFFLKG 254 L +AL QA +TD+ASAIE GL+P+LVEG RN KVTL D ALAE +LKG Sbjct: 182 LRKALEQAT------AVTDEASAIEAQGLQPKLVEGDARNFKVTLPHDVALAELYLKG 233 >C3X223.1 C3X223_OXAFO 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase EC=2.7.7.60 Length = 241 Score = 228 bits (581), Expect = 6e-58, Method: Compositional matrix adjust. Identities = 127/253 (50%), Positives = 161/253 (63%), Gaps = 20/253 (7%) Query: 4 MNPSPSTSSLPPAPVSPPARHFALIPAAGVGARMGGQIPKQYLPLAGQPMLLHALQSFAA 63 M +TS++ P R FALIPAAGVG+RMG PKQYL L G+P+L +AL++F Sbjct: 1 MTTLTNTSAIAP-------RFFALIPAAGVGSRMGAACPKQYLELLGKPVLRYALEAFGE 53 Query: 64 HARIAHTFVVVSAEDGWIDALMT--PALRQ-RVSILRVGGPTRQDSVFNGLNALREQLAD 120 + I +V++S ED W+DA + P L RV LR GG TR+++V NGL+ L + A Sbjct: 54 CSEIERIYVLISHEDEWLDAFLASWPDLDTGRVRFLRCGGVTRRETVLNGLHVLFRECAP 113 Query: 121 ADWVLVHDAARPGLDAALIDRLLDALAQDEVGGLLALPVVDTLKRGDGASSPRSQQTVPR 180 DW+LVHDAARPGL LI RL+ A+A D+ GGLLALPVVDT+KR +TV R Sbjct: 114 DDWILVHDAARPGLTPELIQRLIHAVADDKTGGLLALPVVDTVKR----QGNNGLETVSR 169 Query: 181 AGLWAAQTPQMFPYALLHRALRQAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVT 240 GLW AQTPQMF YA+L AL ++ G +TD+A A+E + L P LVEG RN K+T Sbjct: 170 DGLWLAQTPQMFRYAILREALEKS------GNVTDEAGAVEAMSLTPHLVEGHLRNTKIT 223 Query: 241 LAQDAALAEFFLK 253 D AL E FLK Sbjct: 224 RPADLALVELFLK 236 >C3XA82.1 C3XA82_OXAFO 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2 EC=2.7.7.60 Length = 245 Score = 227 bits (579), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 122/234 (52%), Positives = 154/234 (65%), Gaps = 13/234 (5%) Query: 22 ARHFALIPAAGVGARMGGQIPKQYLPLAGQPMLLHALQSFAAHARIAHTFVVVSAEDGWI 81 AR+FALIPAAGVG+RMG PKQYL L G+P+L H +++F A I FVVVS ED W+ Sbjct: 11 ARYFALIPAAGVGSRMGADCPKQYLFLQGKPVLQHTIEAFLACDGIESVFVVVSPEDEWL 70 Query: 82 DALMTPALR---QRVSILRVGGPTRQDSVFNGLNALREQLADADWVLVHDAARPGLDAAL 138 D + + + RV LR GG TR+DSV NGL+AL + A DW+LVHDAARPGL L Sbjct: 71 DDFVASSPKWDASRVRFLRCGGNTRRDSVLNGLHALFLECAPKDWILVHDAARPGLTPEL 130 Query: 139 IDRLLDALAQDEVGGLLALPVVDTLKRGDGASSPRSQQTVPRAGLWAAQTPQMFPYALLH 198 + +L++ + +++GGLLALPVVDT+K+ S QTV R GLW AQTPQMFPYA L Sbjct: 131 VRKLIETIGPEDIGGLLALPVVDTVKK----QSEEGVQTVSREGLWLAQTPQMFPYAYLM 186 Query: 199 RALRQAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEFFL 252 AL Q ++TD+ASAIE +G P+LVEG N K+T D L E F+ Sbjct: 187 DALEQQ------SDVTDEASAIEAMGQVPKLVEGHLCNSKITKPDDLPLVELFM 234 >Q1H2A3.1 Q1H2A3_METFK 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase EC=2.7.7.60 Length = 238 Score = 226 bits (577), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 124/233 (53%), Positives = 152/233 (65%), Gaps = 7/233 (3%) Query: 20 PPARHFALIPAAGVGARMGGQIPKQYLPLAGQPMLLHALQSFAAHARIAHTFVVVSAEDG 79 P ++ ALIPAAG G+RMG ++PKQYLPL G+P++ HAL FAA RI+ VV++ +D Sbjct: 3 PMSKFHALIPAAGTGSRMGSKLPKQYLPLNGKPLIFHALSLFAAAPRISAVHVVIAPDDH 62 Query: 80 WIDALMTPALRQRVSILRVGGPTRQDSVFNGLNALREQLADADWVLVHDAARPGLDAALI 139 L +V + +GG TR +V NGL A+ Q+AD DW+LVHDAARPGL A++ Sbjct: 63 LWAQYGATGLDAKVVVHALGGATRATTVLNGLEAMVHQVADDDWILVHDAARPGLSMAML 122 Query: 140 DRLLDALAQDEVGGLLALPVVDTLKRGDGASSPRSQQTVPRAGLWAAQTPQMFPYALLHR 199 DRLLD++ D VGGLLA+P+ DTLKR D R T R GLW AQTPQMF YALL Sbjct: 123 DRLLDSVQDDAVGGLLAIPLADTLKRADAGQ--RVAHTESREGLWQAQTPQMFRYALLKN 180 Query: 200 ALRQAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEFFL 252 ALRQA G TD+A A+E LG PRLV G RNLK+T QD LAE L Sbjct: 181 ALRQAS-----GAPTDEAQAVEALGFSPRLVPGELRNLKITYPQDLQLAEAIL 228 >Q2Y751.1 ISPD_NITMU 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase EC=2.7.7.60 Length = 232 Score = 220 bits (560), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 125/232 (53%), Positives = 151/232 (65%), Gaps = 8/232 (3%) Query: 25 FALIPAAGVGARMGGQIPKQYLPLAGQPMLLHALQSFAAHARIAHTFVVVSAEDGWIDAL 84 FALIPAAG G+RMG ++PKQYL LAG+PM+ HAL + R++ FVV+S D Sbjct: 5 FALIPAAGSGSRMGDRMPKQYLTLAGKPMIHHALATLCNSPRLSRVFVVLSPGDVEWARH 64 Query: 85 MTPALRQRVSILRVGGPTRQDSVFNGLNALREQLA--DADWVLVHDAARPGLDAALIDRL 142 ++S+L GG TR ++V NGL A +E A D DWVLVHDAARP L L+D+L Sbjct: 65 DWSEFSSKLSMLECGGATRAETVLNGLKAAQEGTAIEDDDWVLVHDAARPCLGGKLLDKL 124 Query: 143 LDALAQDEVGGLLALPVVDTLKRGDGASSPRSQQTVPRAGLWAAQTPQMFPYALLHRALR 202 +D L +DEVGGLLA+PV DTLKR D + R+++T PR GLW AQTPQMF Y L AL Sbjct: 125 MDELEEDEVGGLLAVPVADTLKRSD--PTCRAERTEPREGLWQAQTPQMFRYRTLVNALS 182 Query: 203 QAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEFFLKG 254 A +TDDA AIE LGLRP+LV RNLKVT QD ALAE LK Sbjct: 183 GAGGV----TMTDDAGAIEALGLRPKLVVSDARNLKVTYPQDLALAELILKN 230 >Q3SK38.1 ISPD_THIDA 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase EC=2.7.7.60 Length = 233 Score = 219 bits (559), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 121/232 (52%), Positives = 150/232 (64%), Gaps = 7/232 (3%) Query: 23 RHFALIPAAGVGARMGGQIPKQYLPLAGQPMLLHALQSFAAHARIAHTFVVVSAEDGWID 82 + +ALIPAAG G+RMGG I KQY+ + PM+ HA+ A RIA FVV+S D + Sbjct: 2 KFYALIPAAGSGSRMGGAIEKQYMDVNSVPMIAHAMMVLAREPRIARIFVVLSPTDKRWN 61 Query: 83 ALMTPALRQRVSILRVGGPTRQDSVFNGLNALREQLADADWVLVHDAARPGLDAALIDRL 142 +R+ +LR GG TR ++V N L+A+ E ADWVLVHDAARP L ++ +L Sbjct: 62 NYEWQGWEERIEVLRCGGGTRAETVLNALDAIAEVCDPADWVLVHDAARPCLPDEMLGKL 121 Query: 143 LDALAQDEVGGLLALPVVDTLKR--GDGASSPRSQQTVPRAGLWAAQTPQMFPYALLHRA 200 LD +A D VGGLLA+PV DTLKR GD +S R + TVPRAGLW AQTPQMF + L A Sbjct: 122 LDEVADDPVGGLLAVPVADTLKRAAGDTSSGTRVEATVPRAGLWQAQTPQMFRHGTLTEA 181 Query: 201 LRQAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEFFL 252 LR A ++TD+ASAIE LGL+P+LVE RNLKVT QD LA L Sbjct: 182 LRAAG-----SDMTDEASAIEKLGLQPQLVESDSRNLKVTYPQDLELASLIL 228 >Q0AFW3.1 ISPD_NITEC 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase EC=2.7.7.60 Length = 233 Score = 215 bits (547), Expect = 6e-54, Method: Compositional matrix adjust. Identities = 124/234 (52%), Positives = 148/234 (63%), Gaps = 11/234 (4%) Query: 23 RHFALIPAAGVGARMGGQIPKQYLPLAGQPMLLHALQSFAAHARIAHTFVVVSAEDG-WI 81 + ALI AAG G+RMG IPKQY PLAG+PM+ HAL++ ARI+ +V++ ED WI Sbjct: 3 KFIALITAAGSGSRMGEDIPKQYRPLAGKPMIYHALRTLCGIARISTVCIVLAPEDTEWI 62 Query: 82 DALMTPALRQRVSILRVGGPTRQDSVFNGLNALR--EQLADADWVLVHDAARPGLDAALI 139 ++ I GG TR +SV NGL ALR + D DW+LVHDAARPGL L+ Sbjct: 63 RHNWRE-FAGKIQIFNCGGATRAESVTNGLKALRAANHVQDQDWILVHDAARPGLSTTLV 121 Query: 140 DRLLDALAQDEVGGLLALPVVDTLKRGDGASSPRSQQTVPRAGLWAAQTPQMFPYALLHR 199 +RLLD LA DEVGGLLA+P+ DTLKR D A R T PR LW AQTPQMF LL Sbjct: 122 ERLLDQLADDEVGGLLAVPLADTLKRADDAG--RVICTEPRERLWQAQTPQMFRMKLLLE 179 Query: 200 ALRQAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEFFLK 253 AL +A ITDDASA+E LGL P+LV G+ N KVT QD LAE L+ Sbjct: 180 ALEKAP-----AGITDDASAVEALGLSPKLVVGNAYNFKVTYPQDLKLAELILR 228 >Q6SG03.1 Q6SG03_9BACT 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase EC=2.7.7.60 Length = 240 Score = 213 bits (542), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 112/238 (47%), Positives = 152/238 (63%), Gaps = 10/238 (4%) Query: 22 ARHFALIPAAGVGARMGGQIPKQYLPLAGQPMLLHALQSFAAHARIAHTFVVVSAED-GW 80 ++ FALIPAAG G+RMG +PKQYL LAG+PM+ HA+ + IA+ FV++S ED W Sbjct: 2 SKFFALIPAAGSGSRMGNSLPKQYLALAGRPMIYHAVHTLCVSPEIANVFVILSPEDREW 61 Query: 81 IDALMTPALRQRVSILRVGGPTRQDSVFNGLNALREQ--LADADWVLVHDAARPGLDAAL 138 + + ++ + GG TR S+ NGL A E+ + + DWV+VHDAARP L L Sbjct: 62 LKYDWSE-FSSKLVVFNCGGETRATSILNGLKAASEKSLIGNGDWVMVHDAARPCLSEEL 120 Query: 139 IDRLLDALAQDEVGGLLALPVVDTLKRGDGASSPRSQQTVPRAGLWAAQTPQMFPYALLH 198 + +L+D L+ DE+GGLLA+P+ DTLKR G ++ R Q+T PR GLW AQTPQMF Y LL Sbjct: 121 LKKLMDELSDDEIGGLLAVPLSDTLKR--GGTNNRVQKTEPRKGLWQAQTPQMFRYKLLL 178 Query: 199 RALRQAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEFFLKGPH 256 AL + +TDDASA+E L L P+LV G N+K+T +D LAE L+ + Sbjct: 179 DALCKPDSI----TMTDDASAVEALDLCPKLVLGDVSNIKITYPKDLVLAELILRAQN 232