BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0178.p (392 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J0C2.1 D8J0C2_HERSS Cystathionine beta-lyase (Cysteine lyase) ... 802 0.0 A6SXU3.1 A6SXU3_JANMA Cystathionine beta-lyase EC=4.4.1.8 610 e-173 A4G6D2.1 A4G6D2_HERAR Cystathionine beta-lyase EC=4.4.1.8 608 e-172 F1W514.1 F1W514_9BURK Cystathionine beta-lyase 599 e-169 C3XB36.1 C3XB36_OXAFO Cystathionine beta-lyase 534 e-150 C3X4X4.1 C3X4X4_OXAFO Cystathionine beta-lyase 518 e-145 E5AQL7.1 E5AQL7_BURRH Cystathionine beta-lyase (EC 4.4.1.8) EC=4... 485 e-135 B5WR96.1 B5WR96_9BURK Cystathionine beta-lyase 482 e-134 D5W7V2.1 D5W7V2_BURSC Cystathionine beta-lyase 477 e-132 B9C6S4.1 B9C6S4_9BURK Cystathionine beta-lyase EC=4.4.1.8 477 e-132 >D8J0C2.1 D8J0C2_HERSS Cystathionine beta-lyase (Cysteine lyase) protein EC=4.4.1.8 Length = 392 Score = 802 bits (2071), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/392 (99%), Positives = 392/392 (100%) Query: 1 VSDPKQTSLTPQTSLVHSSYRAPDGFEAFPVGIHHASTVLFPDVAAMRSRDWREKLGYTY 60 +SDPKQTSLTPQTSLVHSSYRAPDGFEAFPVGIHHASTVLFPDVAAMRSRDWREKLGYTY Sbjct: 1 MSDPKQTSLTPQTSLVHSSYRAPDGFEAFPVGIHHASTVLFPDVAAMRSRDWREKLGYTY 60 Query: 61 GLHGTPTSFVLEARLAEIEGGKYCRVTPSGLAAIAMVNFAFLKSGDDVLLPDNVYGPSKD 120 GLHGTPTSFVLEARLAEIEGGKYCRVTPSGLAAIAMVNFAFLKSGDDVLLPDNVYGPSKD Sbjct: 61 GLHGTPTSFVLEARLAEIEGGKYCRVTPSGLAAIAMVNFAFLKSGDDVLLPDNVYGPSKD 120 Query: 121 LGQWLERDFQITARFYDPMIGEGLAELIRPTTRLVWTEAPGSVSMEVPDIPALCRAAHAK 180 LGQWLERDFQITARFYDPMIGEGLAELIRPTTRLVWTEAPGSVSMEVPDIPALCRAAHAK Sbjct: 121 LGQWLERDFQITARFYDPMIGEGLAELIRPTTRLVWTEAPGSVSMEVPDIPALCRAAHAK 180 Query: 181 GVLVAIDNTWSAGIAFKAFEHGVDIVMQAVTKYQSGGSDVLMGAVIVRDQALNEKLELAH 240 GVLVAIDNTWSAGIAFKAFEHGVDIVMQAVTKYQSGGSDVLMGAVIVRDQALNEKLELAH Sbjct: 181 GVLVAIDNTWSAGIAFKAFEHGVDIVMQAVTKYQSGGSDVLMGAVIVRDQALNEKLELAH 240 Query: 241 MRLGFGVGMDDVYMVLRSLSSMRLRFDAHDAAARKVAAWLKQRPEIVAVLHPAFEDCPGH 300 MRLGFGVGMDDVYMVLRSLSSMRLRF+AHDAAARKVAAWLKQRPEIVAVLHPAFEDCPGH Sbjct: 241 MRLGFGVGMDDVYMVLRSLSSMRLRFEAHDAAARKVAAWLKQRPEIVAVLHPAFEDCPGH 300 Query: 301 AHWKRDFSGAGGLFSVIFDPRYVEAQTDRFVDSLRLFKIGYSWGGAHSLCVPYRMKGMRR 360 AHWKRDFSGAGGLFSVIFDPRYVEAQTDRFVDSLRLFKIGYSWGGAHSLCVPYRMKGMRR Sbjct: 301 AHWKRDFSGAGGLFSVIFDPRYVEAQTDRFVDSLRLFKIGYSWGGAHSLCVPYRMKGMRR 360 Query: 361 AWVREGQLVRFNIGLESPEDLIADIEQALARL 392 AW+REGQLVRFNIGLESPEDLIADIEQALARL Sbjct: 361 AWMREGQLVRFNIGLESPEDLIADIEQALARL 392 >A6SXU3.1 A6SXU3_JANMA Cystathionine beta-lyase EC=4.4.1.8 Length = 380 Score = 610 bits (1574), Expect = e-173, Method: Compositional matrix adjust. Identities = 280/375 (74%), Positives = 330/375 (88%) Query: 15 LVHSSYRAPDGFEAFPVGIHHASTVLFPDVAAMRSRDWREKLGYTYGLHGTPTSFVLEAR 74 ++H+ YRAPDGF A P IHHASTVLF DVA+MRSR+W++K YTYGLHGTPT+F LEAR Sbjct: 1 MIHNDYRAPDGFSALPQAIHHASTVLFKDVASMRSRNWQDKNAYTYGLHGTPTTFTLEAR 60 Query: 75 LAEIEGGKYCRVTPSGLAAIAMVNFAFLKSGDDVLLPDNVYGPSKDLGQWLERDFQITAR 134 LA IE GK+C + PSGLAAIA+V+FAFLKSGDDVL+PDNVY P+++L WL++DF ITAR Sbjct: 61 LAAIEDGKHCVLAPSGLAAIALVDFAFLKSGDDVLIPDNVYNPNRELANWLQQDFGITAR 120 Query: 135 FYDPMIGEGLAELIRPTTRLVWTEAPGSVSMEVPDIPALCRAAHAKGVLVAIDNTWSAGI 194 +YDP+IG G++ LI+P TRL+WTEAPGSVSMEVPD+PA+C+AAHAKGVLVA+DNTW+AG+ Sbjct: 121 YYDPLIGSGISGLIQPNTRLIWTEAPGSVSMEVPDLPAICQAAHAKGVLVALDNTWAAGL 180 Query: 195 AFKAFEHGVDIVMQAVTKYQSGGSDVLMGAVIVRDQALNEKLELAHMRLGFGVGMDDVYM 254 A + FE GVDI+MQA+TKYQSGGSDVLMGAVI +D+ALN++LE AHMRLGFGV DDVY+ Sbjct: 181 ALRGFELGVDIIMQALTKYQSGGSDVLMGAVITQDKALNQRLETAHMRLGFGVAADDVYL 240 Query: 255 VLRSLSSMRLRFDAHDAAARKVAAWLKQRPEIVAVLHPAFEDCPGHAHWKRDFSGAGGLF 314 VLRSL +M+LRF+AHDAAAR VAAWL+ RPEI AVLHPA +CPGHA W+RDFSGAGGLF Sbjct: 241 VLRSLPTMKLRFEAHDAAARTVAAWLQARPEIAAVLHPALPECPGHAIWQRDFSGAGGLF 300 Query: 315 SVIFDPRYVEAQTDRFVDSLRLFKIGYSWGGAHSLCVPYRMKGMRRAWVREGQLVRFNIG 374 SV+FDPRY EAQTDRFVDSL+LFKIG+SWGG HSL VPYRM+ MR W +GQLVR NIG Sbjct: 301 SVVFDPRYSEAQTDRFVDSLQLFKIGFSWGGVHSLAVPYRMQHMRGNWPHQGQLVRLNIG 360 Query: 375 LESPEDLIADIEQAL 389 LE P+DLIADIEQA Sbjct: 361 LEDPQDLIADIEQAF 375 >A4G6D2.1 A4G6D2_HERAR Cystathionine beta-lyase EC=4.4.1.8 Length = 388 Score = 608 bits (1568), Expect = e-172, Method: Compositional matrix adjust. Identities = 279/381 (73%), Positives = 329/381 (86%) Query: 12 QTSLVHSSYRAPDGFEAFPVGIHHASTVLFPDVAAMRSRDWREKLGYTYGLHGTPTSFVL 71 QT+L+H Y AP+GF AFP IHHASTVLF DVA+MRSR+W++K YTYGLHGTPT+F L Sbjct: 8 QTALIHHDYVAPEGFAAFPQAIHHASTVLFKDVASMRSRNWQDKTAYTYGLHGTPTTFTL 67 Query: 72 EARLAEIEGGKYCRVTPSGLAAIAMVNFAFLKSGDDVLLPDNVYGPSKDLGQWLERDFQI 131 EARLA IE GK+C + PSGL+AIAMV+FAFLKSGDDVL+PDNVY P+++L WL DF I Sbjct: 68 EARLAAIENGKHCLLAPSGLSAIAMVDFAFLKSGDDVLIPDNVYNPNRELANWLAHDFGI 127 Query: 132 TARFYDPMIGEGLAELIRPTTRLVWTEAPGSVSMEVPDIPALCRAAHAKGVLVAIDNTWS 191 AR+YDP+IG G+A+LI+P TRL+WTEAPGSVSMEVPDIPA+C+AAHAK VLVA+DNTWS Sbjct: 128 AARYYDPLIGSGIADLIQPNTRLIWTEAPGSVSMEVPDIPAICKAAHAKSVLVALDNTWS 187 Query: 192 AGIAFKAFEHGVDIVMQAVTKYQSGGSDVLMGAVIVRDQALNEKLELAHMRLGFGVGMDD 251 AGIA +AF+ GVDIVMQA+TKYQSGGSDVLMGAVI +DQALN +LELAHMRLGFGV DD Sbjct: 188 AGIALRAFDLGVDIVMQALTKYQSGGSDVLMGAVITQDQALNHRLELAHMRLGFGVSADD 247 Query: 252 VYMVLRSLSSMRLRFDAHDAAARKVAAWLKQRPEIVAVLHPAFEDCPGHAHWKRDFSGAG 311 Y+VLRSL +M+LRF+AHDAAARK+AAWL+ +P+I VLHPA +CPGH W+RDFSGAG Sbjct: 248 SYLVLRSLPTMKLRFEAHDAAARKIAAWLQTQPQIATVLHPALPECPGHEIWQRDFSGAG 307 Query: 312 GLFSVIFDPRYVEAQTDRFVDSLRLFKIGYSWGGAHSLCVPYRMKGMRRAWVREGQLVRF 371 GLFS++FD RY EAQTDRFVDSL+LFKIG+SWGGA+SLCVPYRM+ MRR W +GQL+R Sbjct: 308 GLFSILFDARYTEAQTDRFVDSLKLFKIGFSWGGANSLCVPYRMQHMRRNWPHQGQLLRL 367 Query: 372 NIGLESPEDLIADIEQALARL 392 NIGLE P+DLI D+ QA L Sbjct: 368 NIGLEDPDDLIGDLRQAFDAL 388 >F1W514.1 F1W514_9BURK Cystathionine beta-lyase Length = 390 Score = 599 bits (1544), Expect = e-169, Method: Compositional matrix adjust. Identities = 280/381 (73%), Positives = 325/381 (85%) Query: 12 QTSLVHSSYRAPDGFEAFPVGIHHASTVLFPDVAAMRSRDWREKLGYTYGLHGTPTSFVL 71 QT L HS+Y AP+GF+AFPV IHHASTV+F DVAAMRSR W+ K YTYGLHGTPTSF L Sbjct: 8 QTLLSHSNYTAPEGFDAFPVPIHHASTVVFKDVAAMRSRCWQHKNAYTYGLHGTPTSFTL 67 Query: 72 EARLAEIEGGKYCRVTPSGLAAIAMVNFAFLKSGDDVLLPDNVYGPSKDLGQWLERDFQI 131 EARLAEIE + C + PSGLAAIA+VN LKSGDD+LLPDNVYGP++++ QWL +D I Sbjct: 68 EARLAEIEDAQQCLLAPSGLAAIALVNLGLLKSGDDMLLPDNVYGPNREMAQWLAQDHGI 127 Query: 132 TARFYDPMIGEGLAELIRPTTRLVWTEAPGSVSMEVPDIPALCRAAHAKGVLVAIDNTWS 191 + RFYDPMIG +A LI P TRL+WTEAPGS++MEVPDIPALC AAHA+GVLVAIDNTWS Sbjct: 128 SVRFYDPMIGADIAALIEPNTRLLWTEAPGSITMEVPDIPALCAAAHARGVLVAIDNTWS 187 Query: 192 AGIAFKAFEHGVDIVMQAVTKYQSGGSDVLMGAVIVRDQALNEKLELAHMRLGFGVGMDD 251 AG+AF+AF+HGVDI+MQA+TKYQSGG+DVLMGAV+ RD A+ ++L AHMRLG GVGMDD Sbjct: 188 AGLAFRAFDHGVDIIMQALTKYQSGGADVLMGAVLTRDDAIAQQLGRAHMRLGMGVGMDD 247 Query: 252 VYMVLRSLSSMRLRFDAHDAAARKVAAWLKQRPEIVAVLHPAFEDCPGHAHWKRDFSGAG 311 VYMVLRSL SM LRF AHD AAR++A WLK RPEI VLHPA EDCPGHAHWKRDF+GAG Sbjct: 248 VYMVLRSLPSMPLRFHAHDMAARQIAGWLKSRPEITTVLHPALEDCPGHAHWKRDFTGAG 307 Query: 312 GLFSVIFDPRYVEAQTDRFVDSLRLFKIGYSWGGAHSLCVPYRMKGMRRAWVREGQLVRF 371 GLFSVIFD R+ EAQTDRFV++L+LF+IG+SWGG++SLCVPYR+ MR +W GQLVRF Sbjct: 308 GLFSVIFDARFTEAQTDRFVNALQLFRIGFSWGGSNSLCVPYRIGSMRDSWPHAGQLVRF 367 Query: 372 NIGLESPEDLIADIEQALARL 392 NIGLE+P DLIADIE+A L Sbjct: 368 NIGLENPLDLIADIERATGAL 388 >C3XB36.1 C3XB36_OXAFO Cystathionine beta-lyase Length = 391 Score = 534 bits (1376), Expect = e-150, Method: Compositional matrix adjust. Identities = 241/384 (62%), Positives = 309/384 (80%), Gaps = 1/384 (0%) Query: 10 TPQTSLVHSSYRAPDGFEAFPVGIHHASTVLFPDVAAMRSRDWREKLGYTYGLHGTPTSF 69 + QT +VHS Y P GF AFP ++HASTV+F V A+RSR+W + YTYGLHGTPT+F Sbjct: 7 SKQTGIVHSDYVPPAGFSAFPPAVYHASTVIFDTVEALRSREWIGRDSYTYGLHGTPTTF 66 Query: 70 VLEARLAEIEGGKYCRVTPSGLAAIAMVNFAFLKSGDDVLLPDNVYGPSKDLGQWLERDF 129 LEA+LA IEGG +C + PSGLAAI +V+ AFLK+GDDVL+P+N+Y P+++LG WL +DF Sbjct: 67 TLEAQLANIEGGNHCVLAPSGLAAITIVDMAFLKTGDDVLIPENIYNPNRELGNWLSKDF 126 Query: 130 QITARFYDPMIGEGLAELIRPTTRLVWTEAPGSVSMEVPDIPALCRAAHAKGVLVAIDNT 189 ++ R+YDP+IG G+A+LI P TRL+W E PGS++MEVPDIPA C+AAH KGV+VA+DNT Sbjct: 127 GVSVRYYDPLIGAGIADLILPNTRLIWAETPGSITMEVPDIPAFCKAAHEKGVIVAVDNT 186 Query: 190 WSAGIAFKAFEHGVDIVMQAVTKYQSGGSDVLMGAVIVRDQALNEKLELAHMRLGFGVGM 249 W+AG+ F AF HG D+V+QAVTKYQ+G SD+LMGAVI RD+ LN K+ +AHMRLG GV Sbjct: 187 WAAGLVFDAFGHGADVVVQAVTKYQAGASDLLMGAVITRDEELNRKINMAHMRLGMGVSP 246 Query: 250 DDVYMVLRSLSSMRLRFDAHDAAARKVAAWLKQRPEIVAVLHPAFEDCPGHAHWKRDFSG 309 DD Y+VLRSL+SM++RF+ ++ VA WLKQRPEI +LHPAF DCPGH ++RDF+G Sbjct: 247 DDTYLVLRSLASMKVRFEKSGESSMIVANWLKQRPEISKILHPAFPDCPGHDIFERDFTG 306 Query: 310 AGGLFSVIFDPRYVEAQTDRFVDSLRLFKIGYSWGGAHSLCVPYRMKGMRRAW-VREGQL 368 GGLFSV+FD RY EAQTDRF+++L+LFK+G+SWGG HSL VPYR++ R+ W R+ QL Sbjct: 307 TGGLFSVLFDERYTEAQTDRFLEALKLFKMGFSWGGTHSLSVPYRIRPDRKDWNQRDHQL 366 Query: 369 VRFNIGLESPEDLIADIEQALARL 392 +RF IGLE P DLIAD+EQAL+ L Sbjct: 367 IRFYIGLEDPADLIADLEQALSTL 390 >C3X4X4.1 C3X4X4_OXAFO Cystathionine beta-lyase Length = 390 Score = 518 bits (1334), Expect = e-145, Method: Compositional matrix adjust. Identities = 245/385 (63%), Positives = 305/385 (79%), Gaps = 1/385 (0%) Query: 9 LTPQTSLVHSSYRAPDGFEAFPVGIHHASTVLFPDVAAMRSRDWREKLGYTYGLHGTPTS 68 ++ QT + HS Y AP+GF+AFP + ASTVLF V A+RSR+W + YTYGLHGTPT+ Sbjct: 5 VSKQTRINHSDYVAPEGFDAFPEPTYRASTVLFDSVDALRSREWIGRDSYTYGLHGTPTT 64 Query: 69 FVLEARLAEIEGGKYCRVTPSGLAAIAMVNFAFLKSGDDVLLPDNVYGPSKDLGQWLERD 128 F LEA+LAEIEGG++ + PSGLAAI +V+FAFLKSGDDVL+P+N+Y P+++LG WL RD Sbjct: 65 FTLEAQLAEIEGGRHAVLAPSGLAAITIVDFAFLKSGDDVLIPENIYNPNRELGNWLSRD 124 Query: 129 FQITARFYDPMIGEGLAELIRPTTRLVWTEAPGSVSMEVPDIPALCRAAHAKGVLVAIDN 188 F I R+YDPMIG +A L+R TRLVW E PGSV+MEVPDIPA+C+AAH KG LV +DN Sbjct: 125 FGIHVRYYDPMIGGRIAGLLRDNTRLVWAETPGSVTMEVPDIPAICKAAHEKGALVVLDN 184 Query: 189 TWSAGIAFKAFEHGVDIVMQAVTKYQSGGSDVLMGAVIVRDQALNEKLELAHMRLGFGVG 248 TWSAG+AF AF HG D+V+QAVTKYQ G SD+LMGAVI RD L ++ +AHMRLG GVG Sbjct: 185 TWSAGLAFDAFGHGADVVVQAVTKYQGGASDLLMGAVITRDGELFRRICMAHMRLGMGVG 244 Query: 249 MDDVYMVLRSLSSMRLRFDAHDAAARKVAAWLKQRPEIVAVLHPAFEDCPGHAHWKRDFS 308 DD Y+VLRSLSS+++RF+ +A VA WLK R EI VLHPAF DCPGHA +KRDF+ Sbjct: 245 ADDAYLVLRSLSSLKVRFEKSGESAMTVAHWLKNRAEIHRVLHPAFPDCPGHAIFKRDFT 304 Query: 309 GAGGLFSVIFDPRYVEAQTDRFVDSLRLFKIGYSWGGAHSLCVPYRMKGMRRAW-VREGQ 367 GA GLFSV+F+ Y E QTDRF+++L+LF++G+SWGG HSL VPYR++ RR W +R+ Q Sbjct: 305 GASGLFSVLFNELYTEEQTDRFLEALKLFRMGFSWGGTHSLAVPYRIRPDRRDWNLRQNQ 364 Query: 368 LVRFNIGLESPEDLIADIEQALARL 392 L+RF IGLE PEDLIAD+EQA+ L Sbjct: 365 LIRFYIGLEDPEDLIADLEQAMETL 389 >E5AQL7.1 E5AQL7_BURRH Cystathionine beta-lyase (EC 4.4.1.8) EC=4.4.1.8 Length = 408 Score = 485 bits (1249), Expect = e-135, Method: Compositional matrix adjust. Identities = 229/390 (58%), Positives = 290/390 (74%), Gaps = 2/390 (0%) Query: 4 PKQTSLTPQTSLVHSSYRAPDGFEAFPVGIHHASTVLFPDVAAMRSRDWREKLGYTYGLH 63 P + PQT L+H GFE+F V ASTV+FPD+A+MR+ DWR + YGLH Sbjct: 16 PAGAARDPQTELLHPVTPVQPGFESFSVPTARASTVIFPDLASMRALDWRSDAQWRYGLH 75 Query: 64 GTPTSFVLEARLAEIEGGKYCRVTPSGLAAIAMVNFAFLKSGDDVLLPDNVYGPSKDLGQ 123 TPTS L+ R+A IEGG+Y + PSGL+AI+ V FAF+K+GDDVL+PDNVY P+++ G Sbjct: 76 ATPTSVALQQRIAAIEGGRYALLQPSGLSAISNVYFAFVKAGDDVLVPDNVYSPNREHGD 135 Query: 124 WLERDFQITARFYDPMIGEGLAELIRPTTRLVWTEAPGSVSMEVPDIPALCRAAHAKGVL 183 WL +DF IT R+YDPM+G G+A L+RP TRL+W EAPGS++MEVPD+PA+ A +G++ Sbjct: 136 WLAQDFGITVRYYDPMVGSGMAALLRPNTRLIWLEAPGSITMEVPDVPAITALARERGIV 195 Query: 184 VAIDNTWSAGIAFKAFEHGVDIVMQAVTKYQSGGSDVLMGAVIVRDQALNEKLELAHMRL 243 A+DNT+SAG+ FK FEHGVDI +QA+TKYQSGGSDVLMGA I D L ++ A MR+ Sbjct: 196 TALDNTYSAGLVFKPFEHGVDISVQALTKYQSGGSDVLMGATITADHDLYLAMKRARMRV 255 Query: 244 GFGVGMDDVYMVLRSLSSMRLRFDAHDAAARKVAAWLKQRPEIVAVLHPAFEDCPGHAHW 303 G GV DD +VLR L SM++R+ AH+ +A +A WLK+RPE+ AVLHPAFEDCPGHA+W Sbjct: 256 GLGVSADDCSLVLRGLPSMQVRYRAHERSALAIAGWLKRRPEVAAVLHPAFEDCPGHAYW 315 Query: 304 KRDFSGAGGLFSVIFDPRYVEAQTDRFVDSLRLFKIGYSWGGAHSLCVPYRMKGMRRA-- 361 KRDF+GAGGLFSV+FDPRY AQ D FV+ L LF +G+SWGGAHS+ +PY + MR A Sbjct: 316 KRDFTGAGGLFSVVFDPRYTSAQVDAFVEGLELFALGWSWGGAHSIAMPYDIAAMRTAGM 375 Query: 362 WVREGQLVRFNIGLESPEDLIADIEQALAR 391 W G LVRF IGLE DL ADIE++L R Sbjct: 376 WPHRGVLVRFYIGLEHEADLRADIERSLTR 405 >B5WR96.1 B5WR96_9BURK Cystathionine beta-lyase Length = 394 Score = 482 bits (1240), Expect = e-134, Method: Compositional matrix adjust. Identities = 232/383 (60%), Positives = 285/383 (74%), Gaps = 2/383 (0%) Query: 12 QTSLVHSSYRAPDGFEAFPVGIHHASTVLFPDVAAMRSRDWREKLGYTYGLHGTPTSFVL 71 QT +VH+ + GFE+F + ASTV+FPD+AAMR+ DW+ + YGLH TPT L Sbjct: 11 QTRIVHAEDQITPGFESFSTPVTRASTVVFPDLAAMRALDWKNDAQWRYGLHATPTQIAL 70 Query: 72 EARLAEIEGGKYCRVTPSGLAAIAMVNFAFLKSGDDVLLPDNVYGPSKDLGQWLERDFQI 131 RLA IEGG + + PSGL++I+ V F LKSGDDVL+PDNVY P++D G WL RDF I Sbjct: 71 AQRLAAIEGGNHALLQPSGLSSISNVYFGLLKSGDDVLIPDNVYSPNRDHGDWLARDFGI 130 Query: 132 TARFYDPMIGEGLAELIRPTTRLVWTEAPGSVSMEVPDIPALCRAAHAKGVLVAIDNTWS 191 TAR+YDP+IG +A LIRP TRL+W EAPGSV+MEVPD+PA+ AA A+ V+ AIDNTWS Sbjct: 131 TARYYDPLIGADIAGLIRPNTRLIWIEAPGSVTMEVPDVPAITAAARARKVVTAIDNTWS 190 Query: 192 AGIAFKAFEHGVDIVMQAVTKYQSGGSDVLMGAVIVRDQALNEKLELAHMRLGFGVGMDD 251 AG+AF+ F+HGVDI +QA+TKYQSGG DVLMGA I D+ ++ KL+ A MR+G GV DD Sbjct: 191 AGLAFRPFDHGVDISVQALTKYQSGGGDVLMGATITVDRDVHVKLKAARMRMGIGVSSDD 250 Query: 252 VYMVLRSLSSMRLRFDAHDAAARKVAAWLKQRPEIVAVLHPAFEDCPGHAHWKRDFSGAG 311 ++LRSL SM+LRF HD AA +A WLK+RPEI AVLHPA DCPGH +KRDF+GAG Sbjct: 251 CSLILRSLPSMQLRFAQHDRAALSLATWLKRRPEITAVLHPALADCPGHEVYKRDFTGAG 310 Query: 312 GLFSVIFDPRYVEAQTDRFVDSLRLFKIGYSWGGAHSLCVPYRMKGMRRA--WVREGQLV 369 GLFSV+FD RY ++Q D F +SL LF +G+SWGGAHSL +PY + MR A W G LV Sbjct: 311 GLFSVVFDERYSDSQIDTFCESLELFSLGWSWGGAHSLAMPYHIASMRTAAQWPHRGTLV 370 Query: 370 RFNIGLESPEDLIADIEQALARL 392 RF IGLE DL ADIEQ+LA L Sbjct: 371 RFYIGLEDEADLRADIEQSLASL 393 >D5W7V2.1 D5W7V2_BURSC Cystathionine beta-lyase Length = 394 Score = 477 bits (1228), Expect = e-132, Method: Compositional matrix adjust. Identities = 230/383 (60%), Positives = 283/383 (73%), Gaps = 2/383 (0%) Query: 12 QTSLVHSSYRAPDGFEAFPVGIHHASTVLFPDVAAMRSRDWREKLGYTYGLHGTPTSFVL 71 QT +V + GFE+F + ASTV+FPD+AAMR+ DW+ + YGLH TPT L Sbjct: 11 QTRIVRAEDDITPGFESFSTPVTRASTVVFPDLAAMRALDWKNDAQWRYGLHATPTQIAL 70 Query: 72 EARLAEIEGGKYCRVTPSGLAAIAMVNFAFLKSGDDVLLPDNVYGPSKDLGQWLERDFQI 131 RLA IEGG + + PSGL++I+ V F +K+GDDVL+PDNVY P++D G WL RDF I Sbjct: 71 AQRLAAIEGGNHALLQPSGLSSISNVYFGLMKAGDDVLIPDNVYSPNRDHGDWLARDFGI 130 Query: 132 TARFYDPMIGEGLAELIRPTTRLVWTEAPGSVSMEVPDIPALCRAAHAKGVLVAIDNTWS 191 TAR+YDP+IG G+A+LI+P TRL+W EAPGSV+MEVPD+PA+ AA A+ V AIDNTWS Sbjct: 131 TARYYDPLIGAGIADLIQPNTRLIWIEAPGSVTMEVPDVPAITAAARARNVFTAIDNTWS 190 Query: 192 AGIAFKAFEHGVDIVMQAVTKYQSGGSDVLMGAVIVRDQALNEKLELAHMRLGFGVGMDD 251 AG+AF+ F+HGVDI +QA+TKYQSGG DVLMGA I D+ ++ KL+ A MR+G GV DD Sbjct: 191 AGLAFRPFDHGVDISVQALTKYQSGGGDVLMGATITVDRDVHVKLKAARMRMGIGVSSDD 250 Query: 252 VYMVLRSLSSMRLRFDAHDAAARKVAAWLKQRPEIVAVLHPAFEDCPGHAHWKRDFSGAG 311 ++LRSL SM+LRF HD AA +A WLK RPEIVAVLHPA DCPGH +KRDF+GAG Sbjct: 251 CSLILRSLPSMQLRFAQHDRAALSLAGWLKSRPEIVAVLHPALVDCPGHEVYKRDFTGAG 310 Query: 312 GLFSVIFDPRYVEAQTDRFVDSLRLFKIGYSWGGAHSLCVPYRMKGMRRA--WVREGQLV 369 GLFSV+FD +Y AQ D F +SL LF +G+SWGGAHSL +PY + MR A W G LV Sbjct: 311 GLFSVVFDEQYSAAQIDTFCESLELFSLGWSWGGAHSLAMPYDIASMRTAAQWPHRGTLV 370 Query: 370 RFNIGLESPEDLIADIEQALARL 392 RF IGLE DL ADIEQ+LA L Sbjct: 371 RFYIGLEDEADLRADIEQSLATL 393 >B9C6S4.1 B9C6S4_9BURK Cystathionine beta-lyase EC=4.4.1.8 Length = 393 Score = 477 bits (1227), Expect = e-132, Method: Compositional matrix adjust. Identities = 234/378 (61%), Positives = 280/378 (74%) Query: 12 QTSLVHSSYRAPDGFEAFPVGIHHASTVLFPDVAAMRSRDWREKLGYTYGLHGTPTSFVL 71 QT +V P+GF +F + ASTV+FPD+A MR DWR+ + YGLH TPTS L Sbjct: 11 QTRIVQPDDVIPEGFRSFVPPVARASTVVFPDLATMRQLDWRKDGQWRYGLHATPTSLAL 70 Query: 72 EARLAEIEGGKYCRVTPSGLAAIAMVNFAFLKSGDDVLLPDNVYGPSKDLGQWLERDFQI 131 RLAEIEGG + + PSGLAAI V FA +K+GDDVL+P NVYGP+ D G WL +DF I Sbjct: 71 AQRLAEIEGGTHALLQPSGLAAIMNVYFAVVKAGDDVLIPHNVYGPNADFGNWLAKDFGI 130 Query: 132 TARFYDPMIGEGLAELIRPTTRLVWTEAPGSVSMEVPDIPALCRAAHAKGVLVAIDNTWS 191 +ARFYDP+IG G+AELI+P TRL+W EAPGSV+MEVPD+ A+ AA A+GV+ AIDNT+S Sbjct: 131 SARFYDPLIGAGIAELIQPNTRLIWLEAPGSVTMEVPDVGAITAAARARGVVTAIDNTYS 190 Query: 192 AGIAFKAFEHGVDIVMQAVTKYQSGGSDVLMGAVIVRDQALNEKLELAHMRLGFGVGMDD 251 AG+AFK FEHGVDI +QA+TKYQSGGSD+LMGA I + L+ +L+LA MR G GV +DD Sbjct: 191 AGLAFKPFEHGVDISVQALTKYQSGGSDLLMGATITANAELHAQLKLARMRCGVGVSVDD 250 Query: 252 VYMVLRSLSSMRLRFDAHDAAARKVAAWLKQRPEIVAVLHPAFEDCPGHAHWKRDFSGAG 311 +VLRSL SM+LRFDAH +A +A WLK RPEI VLHP DCPGH + RDF+GAG Sbjct: 251 CSLVLRSLPSMQLRFDAHSKSALSLAKWLKTRPEIATVLHPQLPDCPGHESFVRDFTGAG 310 Query: 312 GLFSVIFDPRYVEAQTDRFVDSLRLFKIGYSWGGAHSLCVPYRMKGMRRAWVREGQLVRF 371 GLFSV+FD RY AQ DRFV+SL LF IG+SWGGA SL VPY + MR W G LVRF Sbjct: 311 GLFSVVFDERYSAAQVDRFVESLALFAIGWSWGGACSLAVPYDVASMRPEWPHRGTLVRF 370 Query: 372 NIGLESPEDLIADIEQAL 389 IGLE DL ADIE+AL Sbjct: 371 YIGLEDEADLRADIERAL 388