BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0071.p (721 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IZM9.1 D8IZM9_HERSS Calcium binding secreted hemolysin protein 1471 0.0 D8IZN0.1 D8IZN0_HERSS Calcium binding secreted hemolysin protein 704 0.0 D8IZN4.1 D8IZN4_HERSS Hemolysin-type calcium binding protein 602 e-169 D8IXI1.1 D8IXI1_HERSS Hemolysin-type calcium binding protein 484 e-134 B1Z0Q1.1 B1Z0Q1_BURA4 Hemolysin-type calcium-binding region 480 e-133 B1K647.1 B1K647_BURCC Hemolysin-type calcium-binding region 479 e-133 E1MSK1.1 E1MSK1_9GAMM Hemolysin-type calcium binding domain protein 172 1e-40 Q8YKJ3.1 Q8YKJ3_NOSS1 Alr7304 protein 167 5e-39 D7DJN9.1 D7DJN9_METS0 Hemolysin-type calcium-binding region 166 1e-38 D0CEI3.1 D0CEI3_ACIBA Hemolysin-type calcium-binding region 160 5e-37 >D8IZM9.1 D8IZM9_HERSS Calcium binding secreted hemolysin protein Length = 984 Score = 1471 bits (3808), Expect = 0.0, Method: Compositional matrix adjust. Identities = 717/721 (99%), Positives = 720/721 (99%) Query: 1 VATASSGPQALTPEALTVRGTQVERWARAAPESAKAALIRKLHFLDGVDKPLTEAQLAAL 60 VATASSGPQALTPEALTVRGTQVERWARAAPESAKAALIRKLHFLDG DKPLTEAQLAAL Sbjct: 264 VATASSGPQALTPEALTVRGTQVERWARAAPESAKAALIRKLHFLDGADKPLTEAQLAAL 323 Query: 61 DKNKDAHLDSDELAGLHAWTDLNEDGIAQAGELTSLPSAMTAAGLASGLRVADYQVYLRG 120 DKNKDAHLDSDELAGLHAWTDLNEDGIAQAGELTSLPSAMTAAGLASGLRVADYQVYLRG Sbjct: 324 DKNKDAHLDSDELAGLHAWTDLNEDGIAQAGELTSLPSAMTAAGLASGLRVADYQVYLRG 383 Query: 121 NASFRTPEQVQAMRSAAQASGKKNQGGAGNDVLFATNGEEINGNGGDDVIYGGDGDDTLV 180 NASFRTPEQVQAMRSAAQASGKKNQGGAGNDVLFATNGEEINGNGGDDVIYGGDGDDTLV Sbjct: 384 NASFRTPEQVQAMRSAAQASGKKNQGGAGNDVLFATNGEEINGNGGDDVIYGGDGDDTLV 443 Query: 181 GGTYSALARGETDNDVLYGGAGKDSLNGGVGNDILDGGTGDDRMYGGAGDDIYVVDSAGD 240 GGTYSALARGETDNDVLYGGAGKDSL+GGVGND+LDGGTGDDRMYGGAGDDIYVVDSAGD Sbjct: 444 GGTYSALARGETDNDVLYGGAGKDSLSGGVGNDLLDGGTGDDRMYGGAGDDIYVVDSAGD 503 Query: 241 GVFENADAGRDTVLAGMSTTLGENVEDLRLLEGGSYNGTGNFLDNRLTGNSQDNILDGLA 300 GVFENADAGRDTVLAGMSTTLGENVEDLRLLEGGSYNGTGNFLDNRLTGNSQDNILDGLA Sbjct: 504 GVFENADAGRDTVLAGMSTTLGENVEDLRLLEGGSYNGTGNFLDNRLTGNSQDNILDGLA 563 Query: 301 GADTMMGGQGNDRYFVDNVGDQVIEEAGEGIDTVYSTVSMTLGANVENLTLMDARTPVHG 360 GADTMMGGQGNDRYFVDNVGDQVIEEAGEGIDTVYSTVSMTLGANVENLTLMDARTPVHG Sbjct: 564 GADTMMGGQGNDRYFVDNVGDQVIEEAGEGIDTVYSTVSMTLGANVENLTLMDARTPVHG 623 Query: 361 EIYGQDALIYGTPKSYLMDYRQGDARPGFLGTCGVTSVANMLTMAGVNVTEKETLQRAID 420 EIYGQDALIYGTPKSYLMDYRQGDARPGFLGTCGVTSVANMLTMAGVNVTEKETLQRAID Sbjct: 624 EIYGQDALIYGTPKSYLMDYRQGDARPGFLGTCGVTSVANMLTMAGVNVTEKETLQRAID 683 Query: 421 RDWCDSDPSLPITLRGGVTCNDLAELMGSFGVAGEVDYRYDEARLVKLLKGGHVVTLCAD 480 RDWCDSDPSLPITLRGGVTCNDLAELMGSFGVAGEVDYRYDEARLVKLLKGGHVVTLCAD Sbjct: 684 RDWCDSDPSLPITLRGGVTCNDLAELMGSFGVAGEVDYRYDEARLVKLLKGGHVVTLCAD 743 Query: 481 AAVFRDMSGYLAGKRVGFHAVAVSGVACSAKTGEVLGFYITDSGPGRYSEMNRFLSVGDL 540 AAVFRDMSGYLAGKRVGFHAVAVSGVACSAKTGEVLGFYITDSGPGRYSEMNRFLSVGDL Sbjct: 744 AAVFRDMSGYLAGKRVGFHAVAVSGVACSAKTGEVLGFYITDSGPGRYSEMNRFLSVGDL 803 Query: 541 RNMDAHESALIYSVDPAKLLHRDSSATGNELDNILMGNQDNNLLTGAKGNDTLTGQAGND 600 RNMDAHESALIYSVDPAKLLHRDSSATGNELDNIL+GNQDNNLLTGAKGNDTLTGQAGND Sbjct: 804 RNMDAHESALIYSVDPAKLLHRDSSATGNELDNILVGNQDNNLLTGAKGNDTLTGQAGND 863 Query: 601 TYVFGKGDGRDLVVDQDATAGNIDTIKFSDARQTNLWFSQVGKDLQIDVLGSTDQVTVKD 660 TYVFGKGDGRDLVVDQDATAGNIDTIKFSDARQTNLWFSQVGKDLQIDVLGSTDQVTVKD Sbjct: 864 TYVFGKGDGRDLVVDQDATAGNIDTIKFSDARQTNLWFSQVGKDLQIDVLGSTDQVTVKD 923 Query: 661 WYAGADNRVERIKTADGKTLYDSDVDKLVQAMASFDPPAATQTSWTDGQTSKGKVLLTVT 720 WYAGADNRVERIKTADGKTLYDSDVDKLVQAMASFDPPAATQTSWTDGQTSKGKVLLTVT Sbjct: 924 WYAGADNRVERIKTADGKTLYDSDVDKLVQAMASFDPPAATQTSWTDGQTSKGKVLLTVT 983 Query: 721 H 721 H Sbjct: 984 H 984 >D8IZN0.1 D8IZN0_HERSS Calcium binding secreted hemolysin protein Length = 1080 Score = 704 bits (1816), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/720 (55%), Positives = 488/720 (67%), Gaps = 45/720 (6%) Query: 11 LTPEALTVRGTQVERWARAAPESAKAALIRKLHFLDGVDKPLTEAQLAALDKNKDAHLDS 70 L+P++L ER ++ ES +A R+LH LD K ++ AQ+AALD N + L++ Sbjct: 397 LSPDSLLPISAINERPSKPELESTSSAAARRLHILDHNGKAMSAAQVAALDLNHNGKLEA 456 Query: 71 DELAGLHAWTDLNEDGIAQAGELTSLPSAMTAAGLASGLRVADYQVYLRGNASFRTPEQV 130 ELA L AWTD NED +AQA ELTSL A+ AAGL + LR DY +Y G + P Q Sbjct: 457 GELADLKAWTDSNEDDLAQASELTSLSDALKAAGLPNTLRATDYSIYTVG----KGPRQE 512 Query: 131 QAMRSA-AQASGKKNQGGAGNDVLFATNGEEINGNGGDDVIYGGDGDDTLVGGTYSALAR 189 +S A SG+ GA VL AT G GDD + G G+D+L Sbjct: 513 WNFKSLLATLSGQ----GAFFFVLPATPQA---GTAGDDQLLGSTGEDSL---------- 555 Query: 190 GETDNDVLYGGAGKDSLNGGVGNDILDGGTGDDRMYGGAGDDIYVVDSAGDGVFENADAG 249 +GG GKD L G GND+LDGG G D +YGG GDD Y+V+S+ D V E + G Sbjct: 556 --------HGGDGKDWLFGFDGNDVLDGGLGADTLYGGDGDDTYIVNSSDDRVVETINGG 607 Query: 250 RDTVLAGMSTTLGENVEDLRLLEGGSYNGTGNFLDNRLTGNSQDNILDGLAGADTMMGGQ 309 DTV+A ST L NVEDLRL+EGG+ NG GN LDN + GN QDNILDG GADTM+GG Sbjct: 608 HDTVIASCSTILAANVEDLRLVEGGNLNGAGNTLDNLIVGNGQDNILDGGVGADTMIGGL 667 Query: 310 GNDRYFVDNVGDQVIEEAGEGIDTVYSTVSMTLGANVENLTLMDARTPVHGEIYGQDALI 369 GND YFVD+ GDQV E A EG+DTVYS +SM L ANVENLTL+D TP+ G + G+ ALI Sbjct: 668 GNDSYFVDDAGDQVTEAADEGVDTVYSRISMRLAANVENLTLLDGGTPLRGTVEGKAALI 727 Query: 370 YGTPKSYLMDYRQGDARPGFLGTCGVTSVANMLTMAGVNVTEKETLQRAIDRDWCDSD-P 428 YG PK+Y +DY+QG+ G+ GTCG TSV N+L MA V+EKE +QRAID+ WC +D P Sbjct: 728 YGAPKAYDLDYQQGNGVTGYDGTCGETSVVNVLRMADQWVSEKEVVQRAIDKKWCITDAP 787 Query: 429 SLPITLRGGVTCNDLAELMGSFGVAGEVDYRYDEARLVKLLKGGHVVTLCADAAVFRDMS 488 S + +GG + D L+ S+G+ E +YD+ +L L+K G V + D+ R S Sbjct: 788 S--ASAKGGSSALDQKRLLESYGLRAEYTLKYDQDKLAALVKEGRGVMVSVDSR--RLWS 843 Query: 489 GYLAGKRVGF--HAVAVSGVACSAKTGEVLGFYITDSGPGRYSEMNRFLSVGDLRNM-DA 545 G GK + F H V V+GVA +A+ GE++GFYI DSG G + R++S +LR M D Sbjct: 844 G---GKGLNFTDHVVTVTGVAYAAEKGELIGFYIADSGRGLAEDATRYVSADELRAMADV 900 Query: 546 HESALIYSVDPAKLLHRDSSATGNELDNILMGNQDNNLLTGAKGNDTLTGQAGNDTYVFG 605 ++++Y++DP KL ++ ATGNELDN L+GN+ +NL+TGAKGNDTL GQAGNDTYVFG Sbjct: 901 RGASMVYTLDPIKLRQQNLEATGNELDNHLVGNRGDNLITGAKGNDTLVGQAGNDTYVFG 960 Query: 606 KGDGRDLVVDQDATAGNIDTIKFSDARQTNLWFSQVGKDLQIDVLGSTDQVTVKDWY--- 662 KGDGRDLV D DATAGNIDTIKFSDARQTNLWF QVG+DLQIDVLG+TDQVTVKDWY Sbjct: 961 KGDGRDLVADHDATAGNIDTIKFSDARQTNLWFRQVGQDLQIDVLGTTDQVTVKDWYVGG 1020 Query: 663 -AGADNRVERIKTADGKTLYDSDVDKLVQAMASFDPPAATQTSWTDGQTSKGKVLLTVTH 721 +G DNR+ERIKTADGKTLYDSDVD+LVQAMASF PP ATQTSW DGQ KG VLLTV H Sbjct: 1021 DSGTDNRIERIKTADGKTLYDSDVDRLVQAMASFAPPPATQTSWRDGQQEKGAVLLTVNH 1080 >D8IZN4.1 D8IZN4_HERSS Hemolysin-type calcium binding protein Length = 1139 Score = 602 bits (1551), Expect = e-169, Method: Compositional matrix adjust. Identities = 322/585 (55%), Positives = 407/585 (69%), Gaps = 13/585 (2%) Query: 146 GGAGNDVLFATNG-EEINGNGGDDVIYGGDGDDTLVGG--TYSALARGETD-NDVLYGGA 201 G G+D L+ G + I G G+DVI GGDGDD + G Y + T +D+LYGGA Sbjct: 559 GNEGDDKLYGEAGNDHIYGGKGNDVIQGGDGDDLIYGDDMEYFWMQPDTTGGDDLLYGGA 618 Query: 202 GKDSLNGGVGNDILDGGTGDDRMYGGAGDDIYVVDSAGDGVFENADAGRDTVLAGMSTTL 261 G DSL GG GND+LDGG+G+D + GG GDD YVVD AGD + E+AD G DTV+A S TL Sbjct: 619 GNDSLFGGSGNDVLDGGSGNDSLVGGLGDDTYVVDGAGDTIREDADQGHDTVVASCSYTL 678 Query: 262 GENVEDLRLLEGGSYNGTGNFLDNRLTGNSQDNILDGLAGADTMMGGQGNDRYFVDNVGD 321 G N+EDLRL EGG +NGTGN DN +TGNSQDNILDG GADT+MGG GND YFVD+V D Sbjct: 679 GRNLEDLRLAEGGQFNGTGNAQDNLITGNSQDNILDGGRGADTLMGGTGNDSYFVDDVND 738 Query: 322 QVIEEAGEGIDTVYSTVSMTLGANVENLTLMDARTPVHGEIYGQDALIYGTPKSYLMDYR 381 +V+E+AGEG+DTV+S +S TLGAN+ENLTL+D+ TP H + G+D L+YG P +DY Sbjct: 739 KVVEQAGEGVDTVFSRISTTLGANLENLTLLDSATPQHEIVNGRDMLVYGYPHYAELDYS 798 Query: 382 QGDARPGFLGTCGVTSVANMLTMAGVNVTEKETLQRAIDRDWCDSDPSLPITLRGGVTCN 441 QGDA G+ GTCG TSV N+ MAG+ VTE + ++RAI WC + + GG Sbjct: 799 QGDAVAGYTGTCGETSVVNLCLMAGLAVTEAQAVKRAIANGWCVTSGE---SQLGGSNQY 855 Query: 442 DLAELMGSFGVAGEVDYRYDEARLVKLLKGGHVVTLCADAAVFRDMSGYLAGKRVGFHAV 501 D L+ S+G+ + Y YDE LVK+LK G + +A D G + G H + Sbjct: 856 DQVALLASYGIRAKAGYGYDEKALVKVLKEGRGALVSVNAGKLWDNPGAVQLGN-GNHVI 914 Query: 502 AVSGVACSAKTGEVLGFYITDSGPGRYSEMNRFLSVGDLRNM-DAHESALIYSVDPAKLL 560 V+GV C TGE GF+I DSG GR + R+LS +LR + D + ++ +VDP K+ Sbjct: 915 TVTGVVCDPGTGEAQGFFIADSGRGRPEDACRYLSKDELRKVADVTDGYMVATVDPIKVP 974 Query: 561 HRDSSATGNELDNILMGNQDNNLLTGAKGNDTLTGQAGNDTYVFGKGDGRDLVVDQDATA 620 + + ATGNELDN++ GN+ N++ G +GNDTL G AGNDTYVF +GDG+D++ DQDAT Sbjct: 975 NENLDATGNELDNVITGNRGANVIRGGRGNDTLIGGAGNDTYVFARGDGQDVIADQDATR 1034 Query: 621 GNIDTIKFSDARQTNLWFSQVGKDLQIDVLGSTDQVTVKDWY----AGADNRVERIKTAD 676 GNIDT++ SD RQTNLWFSQ G DL+IDVLG D++T+KDWY +G+DN +ERI+TAD Sbjct: 1035 GNIDTLQLSDLRQTNLWFSQSGNDLRIDVLGGNDRITIKDWYQGGSSGSDNHIERIRTAD 1094 Query: 677 GKTLYDSDVDKLVQAMASFDPPAATQTSWTDGQTSKGKVLLTVTH 721 G TLYDSDVDKLVQAMASF PP A Q+ WT GQTS+GKVLLTVTH Sbjct: 1095 GNTLYDSDVDKLVQAMASFAPPPALQSEWTPGQTSQGKVLLTVTH 1139 Score = 108 bits (271), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 97/289 (33%), Positives = 140/289 (48%), Gaps = 76/289 (26%) Query: 146 GGAGNDVLFATNGEEINGNGGDDVIYGGDGDDTLVGG----------------------- 182 GGAGND LF G G+D ++G DGDD L+GG Sbjct: 447 GGAGNDTLF--------GREGNDRLFGEDGDDQLLGGEGFDLLDGGAGDDQLFGGLGNDQ 498 Query: 183 -----------------TYSALARGETDNDVLYGGAGKDSLNGGVGND---------ILD 216 T L G+TD+D+++GGAGKD + GG GND L Sbjct: 499 MWGGDGDDTMMGSDVSNTGRPLPAGQTDDDIMFGGAGKDGMFGGAGNDQMWGGDGDDGLY 558 Query: 217 GGTGDDRMYGGAGDDIYVVDSAGDGVFENADAGRDTVLAGMSTTLGENVEDLRLLE---G 273 G GDD++YG AG+D ++ G+ V + D G D + G+++E + G Sbjct: 559 GNEGDDKLYGEAGND-HIYGGKGNDVIQGGD-GDDLI-------YGDDMEYFWMQPDTTG 609 Query: 274 GS---YNGTGNFLDNRLTGNSQDNILDGLAGADTMMGGQGNDRYFVDNVGDQVIEEAGEG 330 G Y G GN + L G S +++LDG +G D+++GG G+D Y VD GD + E+A +G Sbjct: 610 GDDLLYGGAGN---DSLFGGSGNDVLDGGSGNDSLVGGLGDDTYVVDGAGDTIREDADQG 666 Query: 331 IDTVYSTVSMTLGANVENLTLMDARTPVHGEIYGQDALIYGTPKSYLMD 379 DTV ++ S TLG N+E+L L + +G QD LI G + ++D Sbjct: 667 HDTVVASCSYTLGRNLEDLRLAEGGQ-FNGTGNAQDNLITGNSQDNILD 714 Score = 70.1 bits (170), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 65/181 (35%), Positives = 88/181 (48%), Gaps = 25/181 (13%) Query: 164 NGGDDVIYGGDGDDTLVGGTYSALARGETDNDVLYGGAGKDSLNGGVGNDILDGGTGDDR 223 N G D + G GDDTL GG + G ND L+G G D L GG G D+LDGG GDD+ Sbjct: 430 NSGKDTLVGTTGDDTLWGGAGNDTLFGREGNDRLFGEDGDDQLLGGEGFDLLDGGAGDDQ 489 Query: 224 MYGGAGDDIYVVDSAGDGVFENADAGRDTVLAGMSTTLGENVEDLRL---LEGGSYNGTG 280 ++GG G+D GDG ++ G D G G+ +D+ + G + G G Sbjct: 490 LFGGLGNDQMW---GGDG--DDTMMGSDVSNTGRPLPAGQTDDDIMFGGAGKDGMFGGAG 544 Query: 281 N------FLDNRLTGNSQDNILDGLAGADTMMGGQGNDRYFVDNVGDQVIEEAGEGIDTV 334 N D+ L GN D+ L G AG D + GG+GND + + G+G D + Sbjct: 545 NDQMWGGDGDDGLYGNEGDDKLYGEAGNDHIYGGKGND-----------VIQGGDGDDLI 593 Query: 335 Y 335 Y Sbjct: 594 Y 594 >D8IXI1.1 D8IXI1_HERSS Hemolysin-type calcium binding protein Length = 1974 Score = 484 bits (1247), Expect = e-134, Method: Compositional matrix adjust. Identities = 255/474 (53%), Positives = 329/474 (69%), Gaps = 10/474 (2%) Query: 253 VLAGMSTTLGENVEDLRLLEGGSYNGTGNFLDNRLTGNSQDNILDGLAGADTMMGGQGND 312 V A + +L E+ +DL L G S NG GN LDNRLTGN Q+NILDG+ G DTM+GG+G+D Sbjct: 1506 VAAPKNLSLDEDTDDLSL--GSSLNGIGNALDNRLTGNDQNNILDGMGGTDTMIGGKGDD 1563 Query: 313 RYFVDNVGDQVIEEAGEGIDTVYSTVSMTLGANVENLTLMDARTPVHGEIYGQDALIYGT 372 Y++DN GD+++E+AGEG+DTVY+T S TL ANVENL L+DA P + G + L+YG Sbjct: 1564 SYYLDNAGDKIVEQAGEGVDTVYATASTTLAANVENLVLLDASKPQSAVVNGVNVLVYGM 1623 Query: 373 PKSYLMDYRQGDARPGFLGTCGVTSVANMLTMAGVNVTEKETLQRAIDRDWCDSDPSLPI 432 P+SY +DY QG G+ GTCG TSVAN+ M G V+EKE +QRAI + CD+ Sbjct: 1624 PRSYQLDYDQGGEVEGYWGTCGETSVANVTLMGGHAVSEKEVVQRAIKENLCDTAAESAD 1683 Query: 433 TLRGGVTCNDLAELMGSFGVAGEVDYRYDEARLVKLLKGGHVVTLCADAAVFRDMSGYLA 492 T RG + +D L+ FG A V+ D + + +K G V + A+ D+ + Sbjct: 1684 T-RGATSEDDRQALLQDFGFAASVEEELDLKAVAQSIKDGKGVIISVSASKLWDL--HEE 1740 Query: 493 GKRVGFHAVAVSGVACSAKTGEVLGFYITDSGPGRYSEMNRFLSVGDLR-NMDAHESALI 551 + HA+ V+GVACSA +G+++GFYI DSG G S+M RF+S+ LR + + + + Sbjct: 1741 NEDASDHAITVTGVACSAASGKIVGFYIADSGRGLASDMCRFVSLQRLRAATNVYGADTV 1800 Query: 552 YSVDPAKLLHRDSSATGNELDNILMGNQDNNLLTGAKGNDTLTGQAGNDTYVFGKGDGRD 611 + DP KL +++ ATGNELDNIL+GN+ NN LTG KGND L G AGNDTY F KGDG+D Sbjct: 1801 TTDDPIKLRNQNLDATGNELDNILVGNRGNNALTGGKGNDLLIGGAGNDTYAFAKGDGQD 1860 Query: 612 LVVDQDATAGNIDTIKFSDARQTNLWFSQVGKDLQIDVLGSTDQVTVKDWY----AGADN 667 ++ D DAT GN+DT+ FSD +QTNLW S+ G DL+IDVLG+TDQV VKDWY +G+DN Sbjct: 1861 VLYDHDATKGNLDTLSFSDVKQTNLWLSKAGNDLRIDVLGTTDQVLVKDWYVGGDSGSDN 1920 Query: 668 RVERIKTADGKTLYDSDVDKLVQAMASFDPPAATQTSWTDGQTSKGKVLLTVTH 721 VERIKTADGKTLYDSDVDKLVQAMASF PPAATQTSW + GKVLLT++H Sbjct: 1921 HVERIKTADGKTLYDSDVDKLVQAMASFAPPAATQTSWPETAGGNGKVLLTISH 1974 Score = 468 bits (1205), Expect = e-129, Method: Compositional matrix adjust. Identities = 247/451 (54%), Positives = 312/451 (69%), Gaps = 10/451 (2%) Query: 277 NGTGNFLDNRLTGNSQDNILDGLAGADTMMGGQGNDRYFVDNVGDQVIEEAGEGIDTVYS 336 NG GN L NR+TGN +DNILDG+AGADT+ GG+GND Y+VD+ GD+VIE+AGEG+DTVY+ Sbjct: 695 NGIGNALANRITGNDRDNILDGMAGADTLTGGKGNDSYYVDDAGDKVIEKAGEGLDTVYA 754 Query: 337 TVSMTLGANVENLTLMDARTPVHGEIYGQDALIYGTPKSYLMDYRQGDARPGFLGTCGVT 396 TVS TL ANVENL L+DA P + G L+YG PKSY +DY+QGDA G+ GTCG T Sbjct: 755 TVSTTLAANVENLVLLDASKPQTAVVNGIHVLVYGRPKSYQLDYKQGDAVKGYRGTCGET 814 Query: 397 SVANMLTMAGVNVTEKETLQRAIDRDWCDSDPSLPI-TLRGGVTCNDLAELMGSFGVAGE 455 +VAN+ + +EKE ++RAI CD+ P RGG L+ FG+ Sbjct: 815 AVANITMLGDRPASEKEVVERAIKEKLCDT--LTPYDQFRGGSDEKQQQALLKDFGLRSS 872 Query: 456 VDYRYDEARLVKLLKGGHVVTLCADAAVFRDMSGYLAGKRVGFHAVAVSGVACSAKTGEV 515 V +DE + + +K G V + A MS L + H + V+GVACSA TG++ Sbjct: 873 VTEGFDEKSVAQSIKEGKGVAVGVSAGNLWGMS--LRDQDQSDHVITVTGVACSAMTGDI 930 Query: 516 LGFYITDSGPGRYSEMNRFLSVGDLR-NMDAHESALIYSVDPAKLLHRDSSATGNELDNI 574 +GFYI DSG GR S+ RF+S LR + S + + DP KL +++ ATGNELDN+ Sbjct: 931 VGFYIADSGLGRESDRCRFVSSEQLRYAAKVNGSYTLTTDDPIKLRNQNLDATGNELDNV 990 Query: 575 LMGNQDNNLLTGAKGNDTLTGQAGNDTYVFGKGDGRDLVVDQDATAGNIDTIKFSDARQT 634 L+GN+ NN+L+G KGND L G GNDTY F KGDG+D + D DAT N+DT+ F+DA+QT Sbjct: 991 LVGNRGNNVLSGGKGNDLLIGGPGNDTYSFAKGDGQDELYDHDATKDNLDTLTFADAKQT 1050 Query: 635 NLWFSQVGKDLQIDVLGSTDQVTVKDWY----AGADNRVERIKTADGKTLYDSDVDKLVQ 690 NLWFS+ G DL+I VLGS DQVTVKDWY +G DN +ERIKTADGKTLYD+DV++LVQ Sbjct: 1051 NLWFSKAGNDLKISVLGSKDQVTVKDWYVGGDSGTDNHIERIKTADGKTLYDTDVEQLVQ 1110 Query: 691 AMASFDPPAATQTSWTDGQTSKGKVLLTVTH 721 AMASF PP ATQ+SW DGQ+S GKVLLTVTH Sbjct: 1111 AMASFAPPTATQSSWKDGQSSNGKVLLTVTH 1141 Score = 129 bits (325), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 76/205 (37%), Positives = 118/205 (57%), Gaps = 6/205 (2%) Query: 359 HGEIYGQDALIYGTPKSY-LMDYRQGDARPGFLGTCGVTSVANMLTMAGVNVTEKETLQR 417 H +I G+D L+YG PKSY +++Y QG A G+ GTC S+AN+L++AG +V+E + ++R Sbjct: 188 HDKIDGKDVLVYGYPKSYDMLNYSQGFAVSGYYGTCTEASIANLLSIAGQDVSEADVIKR 247 Query: 418 AIDRDWCDSDPSLPITLRGGVTCNDLAELMGSFGVAGEVDYRYDEARLVKLLKGGHVVTL 477 AI WCD+ P LRGG +L+ S+GV V +D +L L+K G V L Sbjct: 248 AIVNGWCDTTSDNPC-LRGGAMTGQQRDLLKSYGVETGVLNDFDPEKLAMLVKQGRGVIL 306 Query: 478 CADAAVF--RDMSGYLAGKRVGFHAVAVSGVACSAKTGEVLGFYITDSGPGRYSEMNRFL 535 ++ ++ L H + ++GVA +A TG +LGFYI+D+G GR + RF+ Sbjct: 307 GVESKELWGAELPPILHTLLNDNHVINLTGVAYAADTGALLGFYISDTGRGRPEDKARFM 366 Query: 536 SVGDLRNMDAHESAL--IYSVDPAK 558 +V +L + + IY++DP K Sbjct: 367 TVSELYKVAHFDYGCNAIYTLDPIK 391 Score = 87.0 bits (214), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 66/213 (30%), Positives = 101/213 (47%), Gaps = 4/213 (1%) Query: 330 GIDTVYSTVSMTLGANVENLTLMDARTPVHGEIYGQDALIYGTPKSYL-MDYRQGDARPG 388 G + +Y T+ A V + D P G+ YG +IYG PK+Y ++Y Q Sbjct: 380 GCNAIY-TLDPIKKAKVPDTGPADPSKPQMGKEYGVKLIIYGDPKAYHNLNYDQPVVMAM 438 Query: 389 FLGTCGVTSVANMLTMAGVNVTEKETLQRAIDRDWCDSDPSLPITLRGGVTCNDLAELMG 448 + T G +VAN+ +AG +++ K LQ AID CD+ L GG T + L+ Sbjct: 439 YTETSGEIAVANIAALAGQSLSPKTVLQTAIDEKLCDTT-KKDRDLGGGTTSENQVALLK 497 Query: 449 SFGVAGEVDYRYDEARLVKLLKGGHVVTLCADAAVFRDMSGYLAGKRVGFHAVAVSGVAC 508 FG+A ++ +D + + + G V L + V + R + +V V+GVA Sbjct: 498 KFGIAATLEQGFDANAVAQHIIEGKGVILRVNGGVLWCKTEPDHPGRSDY-SVTVTGVAF 556 Query: 509 SAKTGEVLGFYITDSGPGRYSEMNRFLSVGDLR 541 SA TGEV GFY+ D G R++ + LR Sbjct: 557 SADTGEVAGFYLADPGFELSGARPRYIEINHLR 589 >B1Z0Q1.1 B1Z0Q1_BURA4 Hemolysin-type calcium-binding region Length = 1534 Score = 480 bits (1236), Expect = e-133, Method: Compositional matrix adjust. Identities = 270/571 (47%), Positives = 360/571 (63%), Gaps = 9/571 (1%) Query: 138 QASGKKNQGGAGNDVLFATNG-EEINGNGGDDVIYGGDGDDTLVGGT-----YSALARGE 191 +A + QGGAG+D L+ +G + + G G+D++YGG GDD LVG T LA GE Sbjct: 943 EAGNDEIQGGAGHDRLYGGDGNDRLFGQVGNDILYGGAGDDLLVGFTGDNEEKRTLAPGE 1002 Query: 192 TDNDVLYGGAGKDSLNGGVGNDILDGGTGDDRMYGGAGDDIYVVDSAGDGVFENADAGRD 251 TD+D LYGG G+D+L GG+GND LDGG G D M GG G+D Y+V+S D + E A+ G D Sbjct: 1003 TDDDYLYGGDGRDTLLGGLGNDYLDGGAGADHMEGGQGNDTYIVNSVNDVILEYANEGYD 1062 Query: 252 TVLAGMSTTLGENVEDLRLLEGGSYNGTGNFLDNRLTGNSQDNILDGLAGADTMMGGQGN 311 TV++ + L N+E+LRL+EG NGTGN LDN + GNS DNILDG+ GADTM+GG+GN Sbjct: 1063 TVISSANYILNANIEELRLVEGFDINGTGNALDNVIVGNSADNILDGVTGADTMIGGKGN 1122 Query: 312 DRYFVDNVGDQVIEEAGEGIDTVYSTVSMTLGANVENLTLMDARTPVHGEIYGQDALIYG 371 D Y+VDNVGD+V+E AGEGIDTV S +S LG +VENL L+D P G + G L+YG Sbjct: 1123 DTYYVDNVGDRVVERAGEGIDTVQSKISYALGDHVENLNLLDFGKPEKGLVDGTSVLVYG 1182 Query: 372 TPKSYLMDYRQGDARPGFLGTCGVTSVANMLTMAGVNVTEKETLQRAIDRDWCDSDPSLP 431 PK+ +DY QGDA P F GTC +TS+AN+LT G TE E ++RAI+ W + P+ Sbjct: 1183 YPKANELDYMQGDAVPTFQGTCALTSIANLLTQIGTPTTEGEVVRRAINNQWAITSPAAT 1242 Query: 432 ITLRGGVTCNDLAELMGSFGVAGEVDYRYDEARLVKLLKGGHVVTLCADAAVFRDMSGYL 491 RGG L+ S+G+ + YDE + L++ G V L +A YL Sbjct: 1243 DYQRGGSNYVQQQALLKSYGITNNLLAGYDEHAVANLVRSGRGVILALNAGRLWGDGAYL 1302 Query: 492 AGKRVGFHAVAVSGVACSAKTGEVLGFYITDSGPGRYSEMNRFLSVGDLRN-MDAHESAL 550 V H V V+G G + GFYI DSG R S+M R++S+ + R+ + S Sbjct: 1303 DSGGVN-HVVTVTGAVYGEADGVLKGFYIADSGRQRVSDMTRYVSLQEFRSAANVPNSYA 1361 Query: 551 IYSVDPAKLLHRDSSATGNELDNILMGNQDNNLLTGAKGNDTLTGQAGNDTYVFGKGDGR 610 IY+ + KL + D TGN LDN ++GN+ NN+L G GND L G GNDTY FG+G GR Sbjct: 1362 IYTAEALKLWNEDIDGTGNALDNTIIGNRGNNVLDGGAGNDILVGGLGNDTYRFGRGAGR 1421 Query: 611 DLVVDQDATAGNIDTIKF-SDARQTNLWFSQVGKDLQIDVLGSTDQVTVKDWYAGADNRV 669 D + D D T GN D I + LWF VG DL+I +LGS+D TV+DWY+G+ ++ Sbjct: 1422 DTIQDDDETLGNNDVISIGAGVSADQLWFRHVGNDLEISILGSSDTATVRDWYSGSRYQI 1481 Query: 670 ERIKTADGKTLYDSDVDKLVQAMASFDPPAA 700 E+I+ DG+TL ++DV+KLVQAMA++ PP A Sbjct: 1482 EQIRLDDGRTLVNADVEKLVQAMAAWSPPGA 1512 Score = 101 bits (251), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 115/352 (32%), Positives = 150/352 (42%), Gaps = 120/352 (34%) Query: 145 QGGAGNDVLFATNGEE-INGNGGDDVIYGGDGDDTLVGGT-----YSALARGETDNDVLY 198 G GND L G + I G GDDVI+GGDGDD LVG T L+ GETDND LY Sbjct: 760 HGDEGNDRLLGEAGHDRIFGEAGDDVIWGGDGDDVLVGFTADNDAKQTLSWGETDNDALY 819 Query: 199 GG------------------------------------AGKDSLNGGVGNDILDGGTGDD 222 GG AG D LNGG GND+L G TG+D Sbjct: 820 GGNGNDALYGGLGNDYLDGGNDDDFLDGGEGDDTLFGGAGSDELNGGNGNDVLSGETGND 879 Query: 223 RMYGGA---------GDDIYVVDSAGD------GVFENAD------AGRDTVLAGMSTTL 261 +++GGA GDDI V +A + +E D AG D +L G+ L Sbjct: 880 KIFGGAGNDTIWGGDGDDILVGFTATNDAKQSLAAWETDDDTIYGGAGNDLILGGLGNDL 939 Query: 262 --GENVEDLRLLEGGS-----------------------YNGTGNFLDNRLTGNSQ---- 292 GE D ++GG+ Y G G+ L TG+++ Sbjct: 940 LYGEAGND--EIQGGAGHDRLYGGDGNDRLFGQVGNDILYGGAGDDLLVGFTGDNEEKRT 997 Query: 293 -----------------DNILDGL--------AGADTMMGGQGNDRYFVDNVGDQVIEEA 327 D +L GL AGAD M GGQGND Y V++V D ++E A Sbjct: 998 LAPGETDDDYLYGGDGRDTLLGGLGNDYLDGGAGADHMEGGQGNDTYIVNSVNDVILEYA 1057 Query: 328 GEGIDTVYSTVSMTLGANVENLTLMDARTPVHGEIYGQDALIYGTPKSYLMD 379 EG DTV S+ + L AN+E L L++ ++G D +I G ++D Sbjct: 1058 NEGYDTVISSANYILNANIEELRLVEG-FDINGTGNALDNVIVGNSADNILD 1108 Score = 100 bits (250), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 103/339 (30%), Positives = 142/339 (41%), Gaps = 93/339 (27%) Query: 44 FLDGVDKPLTEAQLAALDKNKDAHLDSDELAGLHAWTDLNEDGIAQAGELTSLPSAMTAA 103 L+ + L+ L +LD N+D L EL GL W D+NEDGIA AGE +L A Sbjct: 439 LLNAQRQGLSAETLRSLDTNRDGKLSGAELNGLQVWVDMNEDGIADAGEFRALHHAGI-- 496 Query: 104 GLASGLRVADYQVYLRGNASFRTPEQVQAMRSAAQASG---------------------- 141 S +R D+ + RGN+ + ++ + A Sbjct: 497 ---SEIRAVDFDIVTRGNSRYANGPDTAPLKGSEVAGQPGRIYLAPAVPFSNYRALRDTD 553 Query: 142 ------------------KKNQGGA-------GNDVL----FATNGEEIN--------GN 164 K N G GNDV +A G IN Sbjct: 554 NTYWINSSQFIHFGARQIKINNGNRTYLIGTDGNDVFDANYYAAYGHWINSGLLVNFLAG 613 Query: 165 GGDDVIYGGDGDDTLVGGTYSALARGETDNDVLYGGAGKDSLNGGVGNDILDGGTGDDRM 224 GGDDV+ G +D L GGT + G +D LYG G D L GG GND+LDGG+G+D + Sbjct: 614 GGDDVMGGSWRNDNLWGGTGNDTLFGYDGDDRLYGEEGDDELQGGAGNDVLDGGSGNDSL 673 Query: 225 YGGAGDDIYVVDSAGDGVFENADAGRDTVLAGMSTT--------LGENVEDLRLLEGGSY 276 +G AG+DI + GDG D ++ G + + GE +D+ Y Sbjct: 674 FGQAGNDIM---NGGDG---------DDIMMGFTASNEAKQALAPGETDDDVM------Y 715 Query: 277 NGTGNFLDNRLTGNSQDNILDGLAGADTMMGGQGNDRYF 315 G GN +R+ G ++ +DG GAD + GG GND F Sbjct: 716 GGAGN---DRMWGGLGNDYMDGGDGADLVRGGHGNDTIF 751 Score = 85.9 bits (211), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 82/216 (37%), Positives = 107/216 (49%), Gaps = 56/216 (25%) Query: 145 QGGAGNDVLFATNG-EEINGNGGDDVIYGGDGDDTLVGGTYS-----ALARGETDNDVLY 198 QGGAGNDVL +G + + G G+D++ GGDGDD ++G T S ALA GETD+DV+Y Sbjct: 656 QGGAGNDVLDGGSGNDSLFGQAGNDIMNGGDGDDIMMGFTASNEAKQALAPGETDDDVMY 715 Query: 199 GGAGKDSLNGGVGNDILDGG------------------------------------TGDD 222 GGAG D + GG+GND +DGG G D Sbjct: 716 GGAGNDRMWGGLGNDYMDGGDGADLVRGGHGNDTIFGGTGNDELHGDEGNDRLLGEAGHD 775 Query: 223 RMYGGAGDDIYVVDSAGDGVFENADAGRDTVLAGMSTTLGENVEDLRLLEGGS-----YN 277 R++G AGDD+ + GD V A D A + + GE D L GG+ Y Sbjct: 776 RIFGEAGDDV-IWGGDGDDVLVGFTADND---AKQTLSWGETDND--ALYGGNGNDALYG 829 Query: 278 GTGNFLDNRLTGNSQDNILDGLAGADTMMGGQGNDR 313 G GN + L G + D+ LDG G DT+ GG G+D Sbjct: 830 GLGN---DYLDGGNDDDFLDGGEGDDTLFGGAGSDE 862 >B1K647.1 B1K647_BURCC Hemolysin-type calcium-binding region Length = 1532 Score = 479 bits (1233), Expect = e-133, Method: Compositional matrix adjust. Identities = 270/571 (47%), Positives = 361/571 (63%), Gaps = 9/571 (1%) Query: 138 QASGKKNQGGAGNDVLFATNG-EEINGNGGDDVIYGGDGDDTLVGGT-----YSALARGE 191 +A + QGG G+D L+ +G + + G G+D++YGG GDD LVG T L GE Sbjct: 941 EAGNDEIQGGDGHDKLYGGDGNDRLFGQVGNDILYGGAGDDLLVGFTGDNEAKRTLGPGE 1000 Query: 192 TDNDVLYGGAGKDSLNGGVGNDILDGGTGDDRMYGGAGDDIYVVDSAGDGVFENADAGRD 251 TD+D LYGG G D+L GG+G+D LDGG G D M GG G+D Y+V+S D V E A+ G D Sbjct: 1001 TDDDYLYGGEGNDTLLGGLGDDYLDGGAGADHMEGGEGNDTYIVNSVNDVVLEYANEGYD 1060 Query: 252 TVLAGMSTTLGENVEDLRLLEGGSYNGTGNFLDNRLTGNSQDNILDGLAGADTMMGGQGN 311 TV++ + L N+E+LRL+EG + NGTGN LDNR+ GNS DNILDG+ GADTM+GG+GN Sbjct: 1061 TVISSANYILNANIEELRLVEGFNINGTGNALDNRIVGNSADNILDGVTGADTMIGGKGN 1120 Query: 312 DRYFVDNVGDQVIEEAGEGIDTVYSTVSMTLGANVENLTLMDARTPVHGEIYGQDALIYG 371 D Y+VDNVGD+V+E AGEGIDTV S +S TLG +VENL L+D P G + G +YG Sbjct: 1121 DTYYVDNVGDRVVEFAGEGIDTVQSKISYTLGEHVENLNLLDFGKPEKGLVDGVAVHVYG 1180 Query: 372 TPKSYLMDYRQGDARPGFLGTCGVTSVANMLTMAGVNVTEKETLQRAIDRDWCDSDPSLP 431 PK+ +DY QGDA P F GTC +TS+AN+LT G +TE + ++RAID W + P+ Sbjct: 1181 YPKANELDYMQGDAVPRFQGTCALTSIANLLTQTGTPITEGDVVRRAIDNQWAVTSPAAT 1240 Query: 432 ITLRGGVTCNDLAELMGSFGVAGEVDYRYDEARLVKLLKGGHVVTLCADAAVFRDMSGYL 491 RGG L+ S+G+A + YDE + L++ G V L ++ + S YL Sbjct: 1241 DYQRGGSNYVQQQALLASYGIANNLLAGYDEHAVANLVRSGRGVILALNSGRLWEDSAYL 1300 Query: 492 AGKRVGFHAVAVSGVACSAKTGEVLGFYITDSGPGRYSEMNRFLSVGDLR-NMDAHESAL 550 G V H V V+G GE+ GFYI DSG R S+M R++S+ + R + + Sbjct: 1301 DGGGVN-HVVTVTGAVYGDADGELKGFYIADSGRRRVSDMTRYISLQEFRAAANVPNAYA 1359 Query: 551 IYSVDPAKLLHRDSSATGNELDNILMGNQDNNLLTGAKGNDTLTGQAGNDTYVFGKGDGR 610 IY+ + KL + D TGN LDN ++GN+ NN+L G GND L G GNDTY FG+G G Sbjct: 1360 IYTAEALKLWNEDIDGTGNALDNTIIGNRGNNVLDGGAGNDILIGGLGNDTYRFGRGSGC 1419 Query: 611 DLVVDQDATAGNIDTIKF-SDARQTNLWFSQVGKDLQIDVLGSTDQVTVKDWYAGADNRV 669 D + D D T GN D I + LWF VG DL+I +LG+ D TV+DWY G+ ++ Sbjct: 1420 DTIRDDDETLGNSDVISIGAGVSADQLWFRHVGNDLEISILGTGDTATVRDWYLGSRYQI 1479 Query: 670 ERIKTADGKTLYDSDVDKLVQAMASFDPPAA 700 E+I+ DG+TL ++DV+KLVQAMA + PPAA Sbjct: 1480 EQIRVDDGRTLVNADVEKLVQAMAVWSPPAA 1510 Score = 98.6 bits (244), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 107/327 (32%), Positives = 137/327 (41%), Gaps = 121/327 (37%) Query: 145 QGGAGNDVLFATNG-EEINGNGGDDVIYGGDGDDTLVGGTYS-----ALARGETDNDVLY 198 G AGND L G + I G GDDV++GGDGDD LVG T S L+ GE+DND+LY Sbjct: 758 HGDAGNDRLLGEAGNDRIFGEAGDDVLWGGDGDDVLVGFTASNDAKQTLSWGESDNDMLY 817 Query: 199 GG------------------------------------AGKDSLNGGVGNDILDGGTGDD 222 GG AG D LNGG G+D L G TG+D Sbjct: 818 GGNGNDALYGGLGNDYLDGGNDNDFLDGGDGDDRLFGGAGDDELNGGNGHDALSGETGND 877 Query: 223 RMYGGA---------GDDIYVVDSAGD------GVFENAD------AGRDTVLAGMSTTL 261 +++GGA GDDI V +A + +E D AG D +L G+ L Sbjct: 878 KIFGGAGNDTIWGGDGDDILVGFTASNDAKQSLAAWETDDDTIYGGAGNDLILGGLGNDL 937 Query: 262 GENVEDLRLLEGGS-----YNGTGNFLDNRLTGNSQDNIL-------------------- 296 ++GG Y G GN +RL G ++IL Sbjct: 938 LHGEAGNDEIQGGDGHDKLYGGDGN---DRLFGQVGNDILYGGAGDDLLVGFTGDNEAKR 994 Query: 297 ------------------------------DGLAGADTMMGGQGNDRYFVDNVGDQVIEE 326 DG AGAD M GG+GND Y V++V D V+E Sbjct: 995 TLGPGETDDDYLYGGEGNDTLLGGLGDDYLDGGAGADHMEGGEGNDTYIVNSVNDVVLEY 1054 Query: 327 AGEGIDTVYSTVSMTLGANVENLTLMD 353 A EG DTV S+ + L AN+E L L++ Sbjct: 1055 ANEGYDTVISSANYILNANIEELRLVE 1081 Score = 90.5 bits (223), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 99/328 (30%), Positives = 131/328 (39%), Gaps = 94/328 (28%) Query: 55 AQLAALDKNKDAHLDSDELAGLHAWTDLNEDGIAQAGELTSLPSAMTAAGLASGLRVADY 114 + L + D N+D L EL GL W D NEDGI GE SL A +R DY Sbjct: 449 SALQSRDANRDGKLTGAELDGLQVWIDANEDGIGDVGEFRSLAQAGITE-----IRAVDY 503 Query: 115 QVYLRGNASFRTPEQVQAMRSAAQASGKKNQ----------------------------- 145 V RGN S+ V A +AS Sbjct: 504 DVITRGN-SYHASAPVAAPLKPWEASQPGRMYLAPAVPLSNYRTLRDNDKIYWINSRDFI 562 Query: 146 ------------------GGAGNDVL----FATNGEEINGN--------GGDDVIYGGDG 175 G GNDV +A G I+ N G+D++ G Sbjct: 563 MFGPTQIKVSPSNRSYLIGTDGNDVFDANYYAAYGHWIDSNLLVNFLAGDGNDMMGGSSR 622 Query: 176 DDTLVGGTYSALARGETDNDVLYGGAGKDSLNGGVGNDILDGGTGDDRMYGGAGDDIYVV 235 +D L GGT + G +D LYG G D LNGG GND+LDGG G+D+++G G+DI Sbjct: 623 NDNLWGGTGNDTLFGYDGDDRLYGEEGDDELNGGAGNDVLDGGIGNDKLFGHVGNDIM-- 680 Query: 236 DSAGDGVFENADAGRDTVLAGMSTT--------LGENVEDLRLLEGGSYNGTGNFLDNRL 287 + GDG D ++ G + + GE +D+ Y G GN +R+ Sbjct: 681 -NGGDG---------DDIMLGFTASNDSKQTLAWGETDDDIM------YGGAGN---DRM 721 Query: 288 TGNSQDNILDGLAGADTMMGGQGNDRYF 315 G + +DG GAD + GG GND F Sbjct: 722 WGGVGHDYMDGGDGADFVSGGDGNDTVF 749 >E1MSK1.1 E1MSK1_9GAMM Hemolysin-type calcium binding domain protein Length = 2762 Score = 172 bits (437), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 210/627 (33%), Positives = 286/627 (45%), Gaps = 116/627 (18%) Query: 129 QVQAMRSAAQASGKKN--------------QGGAGNDVLFATNGEEI-NGNGGDDVIYGG 173 Q+QA+ SA SG + QG GND L+ NG ++ +G G+D + GG Sbjct: 2028 QLQALVSAVSNSGTEQADFLEAWVDENATLQGLGGNDDLYGNNGNDLLDGGAGNDYLSGG 2087 Query: 174 DGDDTLV------------------------------------GGTYSALARGETDNDVL 197 G+DT + GT + G ++VL Sbjct: 2088 SGNDTYIIDSLGDVIAENADEGTDTVQSSISYTLNANVENLALTGTAAINGTGNGLDNVL 2147 Query: 198 YGGAGKDSLNGGVGNDILDGGTGDDRMYGGAGDDIYVVDSAGDGVFENA--DAGRDTVLA 255 G + ++L GG+GND LDGG+G D + GG G+D YVVD GD V E + DTV + Sbjct: 2148 IGNSAANTLTGGLGNDTLDGGSGADTLIGGLGNDTYVVDDLGDVVKETSALKTEIDTVQS 2207 Query: 256 GMSTTLGENVEDLRLLEGGSYNGTGNFLDNRLTGNSQDNILDGLAGADTMMGGQGNDRYF 315 ++ TLG +E+L L + NGTGN L+N LTGNS DNIL+G AGAD ++GG GND Y Sbjct: 2208 SITYTLGSKLENLTLTGTSAINGTGNSLNNTLTGNSGDNILNGGAGADHLIGGLGNDTYV 2267 Query: 316 VDNVGDQVIEEAGEGIDTVYSTVSMTLGANVENLTLMDARTPVHGEIYGQDALIYGTPKS 375 V NV D V E EGIDTV S+V+ TL N+ENLTL A +P++G D ++ G Sbjct: 2268 VSNVNDAVTEGDDEGIDTVQSSVTYTLSDNIENLTLTGA-SPINGTGNDLDNILIGNAGK 2326 Query: 376 YLMDYRQG-DARPGFLG-----------------TCGVTSVANMLTMA-GVNVTEKETLQ 416 +++ +G DA G G G +V + +T G NV EK TL Sbjct: 2327 NVLNGGEGSDAMTGGAGNDTYVVDNTGDVVTENANEGTDTVQSFITYTLGENV-EKLTL- 2384 Query: 417 RAIDRDWCDS-DPSLPITLRGGVTCNDLAELMGS---FGVAGEVDYRYDEAR-LVKLLKG 471 I D D +L TL G N L G+ G G Y D A +VK Sbjct: 2385 --IGTDAIDGIGNALNNTLTGNEAANILDGSTGADILIGGLGNDTYVVDNASDVVK---- 2438 Query: 472 GHVVTLCADAAVFRDMSGYLAGKRVGFHAVAVSGVACSAKTGEVLGF-YITDSGP----- 525 TL + + Y G V + ++G A TG L I +SG Sbjct: 2439 -ETSTLSTEIDTVQSSVSYTLGSNV--ENLILTGAAAINGTGNSLNNQLIGNSGDNVLTG 2495 Query: 526 GRYSEMNRFLSVGDLRN----MDAHESALIYSVDPAKLLHRDSSATGNELD-----NILM 576 G+ S++ GDL N +A L D L D++ T N LD + L Sbjct: 2496 GKGSDLLN----GDLGNDTLKGNAGNDILQGGADNDSL--SDTAGT-NLLDGGSGADTLS 2548 Query: 577 GNQDNNLLTGAKGNDTLTGQAGNDTYVFGKGDGRDLVVDQDATAGNIDTIKFSDARQ-TN 635 GN N + G GNDT+T G D F +GDG D+V + G +T+ Q + Sbjct: 2549 GNAANEMFVGGTGNDTITTGNGADIIAFNRGDGMDVV---NGGVGTDNTLSLGGGIQYAD 2605 Query: 636 LWFSQVGKDLQIDVLGSTDQVTVKDWY 662 L S+ GKDL ++ G+ DQVT+ WY Sbjct: 2606 LALSKSGKDLIVEA-GNGDQVTLSGWY 2631 Score = 80.5 bits (197), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 182/686 (26%), Positives = 268/686 (39%), Gaps = 158/686 (23%) Query: 126 TPEQVQAMRSAAQASGKKNQGGAGNDVLFATNGEEINGNG-GDDVIYGGDGDDTLVGGTY 184 T +R + G G DV++A G++ G G+DV++G DG+D+L Sbjct: 621 TIATTNGIRQYSPVVGDPAPADFGADVIYAGAGDDYVWAGQGNDVLFGEDGNDSL----- 675 Query: 185 SALARGETDNDVLYGGAGKDSLNGGVGNDILDGGTGDDRMYGGAGDDIYVVDSAGDGVFE 244 G+ NDV+ GGAG D + G G+D+L GGTG+D + GGAG+D Y+ + GDG Sbjct: 676 ----NGQEGNDVIVGGAGVDIIGGQQGDDVLIGGTGNDTLVGGAGNDTYIFNR-GDGRDT 730 Query: 245 NADAGRDT-VLAGMSTTLGE--------------------------------NVEDLRLL 271 D +D+ +L G + G+ +V R Sbjct: 731 VIDPDKDSNLLFGEGISAGDITLRLGSLELDLGNGDQVHIDGFDPNDVFNSSSVSTFRFA 790 Query: 272 EGGS----------YNGTGNFLDNRLTGNSQDNILDGLAGADTMMGGQGNDRYFVDNVGD 321 +G ++ G+ D+ LTG + + ++GL G DT++GG GND +D Sbjct: 791 DGTELSINQLLARGFDLDGSSGDDTLTGTNTTDRINGLGGNDTLIGGAGNDS--LDGGAG 848 Query: 322 QVIEEAGEGIDTVYS-----TVSMTLGANVENLTLMDARTPVHGEIYGQDALIYGTPKSY 376 I G G DT + T++ T G N L L A G G A YG Y Sbjct: 849 ADILMGGAGDDTYLNVTGEDTLADTEGHNT--LQLAQANGLGAG---GLKATHYGNQSQY 903 Query: 377 L---MDYRQGD---ARPGFLGTCGVTSVA-----NMLTMAGVNVTEKETLQR-------- 417 L + GD + F GT A ++ T+ G ++T LQ Sbjct: 904 LRLDIALDNGDILKIQDAFFGTDATLQFAKGNQLDLETLVGASLTTALNLQLDNSGGKLY 963 Query: 418 ---------------AIDRDWCDSDPSLPITLRGGVTCNDLAELMGS---FGVAGEVDYR 459 + W D TL GG + L G G AG Y+ Sbjct: 964 GGAGADSLHGGSGDDMLSGAWGDD------TLSGGAGNDTLIGGAGRDLLLGGAGNDAYQ 1017 Query: 460 YDE---ARLVKLLKGGHVVTLCAD--AAVFRDMSGYLAGKRVGFHAVAVSGVACSAKTGE 514 A L+ +G +++ AD AA + +AG+ + V+GV + T Sbjct: 1018 LSATSGADLITDTEGQNIIRFAADISAANLTVSTLTMAGQPA--LRMKVNGVEAATIT-- 1073 Query: 515 VLGFYITDSGPGRYSEMNRFLSVGDLRNMDAHESALIYSVDPAKLLHRDSSATGNELDNI 574 SG YS D M + E L + +P + GN DN Sbjct: 1074 --------SGVDHYS-----FEFADGSRMTSAEFLLNFRAEPQTVY-------GNGTDNT 1113 Query: 575 LMGNQDNNLLTGAKGNDTL---------TGQAGNDTYVFGKGDGRDLVVDQDATA---GN 622 L G Q + L G GND+L G G+D Y + GDG+D++ + D + Sbjct: 1114 LYGGQAGDTLYGQDGNDSLWGGAGDDLLDGGLGSDDYHYRPGDGQDVIQETDMPGSGQSS 1173 Query: 623 IDTIKF-SDARQTNLWFS-QVGKDLQIDVLGSTDQVTVKDWYAGADNRVERIKTADG--- 677 D + F + +++ F Q DL + V G D +TV WY RVE + ADG Sbjct: 1174 QDRVIFGAGIALSDVTFKHQANGDLSVTVSGLADAITVTGWYTDPAKRVEAFEFADGLQV 1233 Query: 678 --KTLYDSDVDKLVQAMASFDPPAAT 701 TL DV L Q A +P + T Sbjct: 1234 TADTLAALDVTPL-QGSAGNNPLSGT 1258 Score = 78.6 bits (192), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 42/125 (33%), Positives = 79/125 (63%), Gaps = 3/125 (2%) Query: 573 NILMGNQDNNLLTGAKGNDTLTGQAGNDTYVFGKGDGRDLVVDQDA--TAGNIDTIKFSD 630 ++L+G + +++L G ND L+G GND Y+FG GDG+D + + AGN+DT++F Sbjct: 1914 DMLIGGEGDDVLYGGADNDYLSGGLGNDVYMFGLGDGQDAIENWTGPDIAGNVDTLRFGV 1973 Query: 631 ARQT-NLWFSQVGKDLQIDVLGSTDQVTVKDWYAGADNRVERIKTADGKTLYDSDVDKLV 689 ++ F++ G+DL + + G++DQ+T+++W G ++R++ ADG Y + + LV Sbjct: 1974 GIAAGDISFTRTGEDLVLGINGTSDQLTIRNWRYGEAYHIKRVEFADGTEWYVAQLQALV 2033 Query: 690 QAMAS 694 A+++ Sbjct: 2034 SAVSN 2038 >Q8YKJ3.1 Q8YKJ3_NOSS1 Alr7304 protein Length = 4936 Score = 167 bits (423), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 104/231 (45%), Positives = 135/231 (58%), Gaps = 28/231 (12%) Query: 157 NGEEINGNGGDDVIYGGDGDDTLVGGTYSALARGETDNDVLYGGAGKDSLNGGVGNDILD 216 N + + GN G+D ++GG G+D+L GG + G ND L G AG D+L+GG GND LD Sbjct: 4537 NDDTLRGNAGNDTLFGGSGNDSLSGGIGDDILNGADGNDNLKGEAGNDTLDGGAGNDSLD 4596 Query: 217 GGTGDDRMYGGAGDDIYVVDSAGDGVFENADAGRDTVLAGMSTTLGENVEDLRLLEGGSY 276 GG GDD M GGAG+D Y VDS+ D + E D G DTV A +S TL +N+E+L L + Sbjct: 4597 GGLGDDVMTGGAGNDTYFVDSSNDTIAEETDGGSDTVNASVSWTLDDNLENLTLTGSNAI 4656 Query: 277 NGTGNFLDNRLTGNSQDNI---------------------------LDGLAGADTMMGGQ 309 NGTGN L N +TGNS DNI LDG G D M GG Sbjct: 4657 NGTGNALRNTITGNSADNILSGGDNDDTLRGNAGNDILNGGAGNDSLDGGLGDDVMTGGA 4716 Query: 310 GNDRYFVDNVGDQVIEEAGEGIDTVYSTVSMTLGANVENLTLMDARTPVHG 360 ND YFVD+ D +IEEA G DTV +++++TLG ++ENL L+ +P+ G Sbjct: 4717 SNDTYFVDSSNDTIIEEADGGTDTVRASITLTLGDHLENLILI-GNSPIDG 4766 Score = 132 bits (333), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 80/159 (50%), Positives = 98/159 (61%) Query: 157 NGEEINGNGGDDVIYGGDGDDTLVGGTYSALARGETDNDVLYGGAGKDSLNGGVGNDILD 216 N + + G G+D +YGG G+D+L GG + GE ND L G G D LNG GND LD Sbjct: 4393 NDDILRGGEGNDTLYGGAGNDSLDGGIGNDSLNGEDGNDNLKGDVGNDILNGNAGNDTLD 4452 Query: 217 GGTGDDRMYGGAGDDIYVVDSAGDGVFENADAGRDTVLAGMSTTLGENVEDLRLLEGGSY 276 GG GDD M GGAG+DIY VDS+ D + E + G DTV A ++ TLG N+E+L L Sbjct: 4453 GGLGDDVMTGGAGNDIYFVDSSNDTIIEELNEGTDTVNASINWTLGNNLENLTLTGSNGI 4512 Query: 277 NGTGNFLDNRLTGNSQDNILDGLAGADTMMGGQGNDRYF 315 NGTGN L N +TGN+ DNIL G DT+ G GND F Sbjct: 4513 NGTGNALKNIITGNNGDNILSGGDNDDTLRGNAGNDTLF 4551 Score = 127 bits (320), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 89/219 (40%), Positives = 114/219 (52%), Gaps = 45/219 (20%) Query: 170 IYGGDGDDTLVGGTYSALARGETDNDVLYGGAGKDSLNGGVGNDILDGGTGDDRMYGGAG 229 I G G++TL G +ND + G G D + G GND L+GGTG D M GG G Sbjct: 4154 IVGTSGNNTLAG---------TPNNDNIQGLGGNDIIFGLAGNDTLNGGTGSDTMTGGLG 4204 Query: 230 DDIYVVDSAGDGVFENADAGRDTVLAGMSTTLGENVEDLRLLEGGSYNGTGNFLDNRLTG 289 DD Y+VD+ D V EN + G DTV + +S TL ENVE+L L + +GTGN L N +TG Sbjct: 4205 DDTYIVDNNVDKVVENLNEGIDTVRSSISYTLLENVENLILTGTSNISGTGNILSNIITG 4264 Query: 290 NSQDN------------------------------------ILDGLAGADTMMGGQGNDR 313 NS N ILDG G D M GG GND Sbjct: 4265 NSGANTLNGKAGDDILNGEGGNDNLKGEDGNDVLNGGAGNDILDGGLGDDVMTGGVGNDI 4324 Query: 314 YFVDNVGDQVIEEAGEGIDTVYSTVSMTLGANVENLTLM 352 Y+VD+ D +I+E EG DTV + ++ TLG ++ENLTL+ Sbjct: 4325 YYVDSSNDIIIDELNEGTDTVNTIITWTLGNHLENLTLI 4363 Score = 122 bits (306), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 83/198 (41%), Positives = 108/198 (54%), Gaps = 18/198 (9%) Query: 118 LRGNASFRTPEQVQAMRSAAQASGKKNQGGAGNDVLFATNGEEINGNGGDDVIYGGDGDD 177 +R + S+ E V+ + +G N G GN + I GN G + + G GDD Sbjct: 4228 VRSSISYTLLENVENLI----LTGTSNISGTGNIL-----SNIITGNSGANTLNGKAGDD 4278 Query: 178 TLVGGTYSALARGETDNDVLYGGAGKDSLNGGVGNDILDGGTGDDRMYGGAGDDIYVVDS 237 L GE ND L G G D LNGG GNDILDGG GDD M GG G+DIY VDS Sbjct: 4279 IL---------NGEGGNDNLKGEDGNDVLNGGAGNDILDGGLGDDVMTGGVGNDIYYVDS 4329 Query: 238 AGDGVFENADAGRDTVLAGMSTTLGENVEDLRLLEGGSYNGTGNFLDNRLTGNSQDNILD 297 + D + + + G DTV ++ TLG ++E+L L+ + NGTGN L N + GNS DNIL Sbjct: 4330 SNDIIIDELNEGTDTVNTIITWTLGNHLENLTLIGSSAINGTGNALKNIIIGNSADNILS 4389 Query: 298 GLAGADTMMGGQGNDRYF 315 G D + GG+GND + Sbjct: 4390 GGDNDDILRGGEGNDTLY 4407 Score = 122 bits (305), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 73/157 (46%), Positives = 93/157 (59%), Gaps = 18/157 (11%) Query: 161 INGNGGDDVIYGGDGDDTLVGGTYSALARGETDNDVLYGGAGKDSLNGGVGNDILDGGTG 220 I GN D+++ GGD DDTL G AG D LNGG GND LDGG G Sbjct: 4667 ITGNSADNILSGGDNDDTL------------------RGNAGNDILNGGAGNDSLDGGLG 4708 Query: 221 DDRMYGGAGDDIYVVDSAGDGVFENADAGRDTVLAGMSTTLGENVEDLRLLEGGSYNGTG 280 DD M GGA +D Y VDS+ D + E AD G DTV A ++ TLG+++E+L L+ +GTG Sbjct: 4709 DDVMTGGASNDTYFVDSSNDTIIEEADGGTDTVRASITLTLGDHLENLILIGNSPIDGTG 4768 Query: 281 NFLDNRLTGNSQDNILDGLAGADTMMGGQGNDRYFVD 317 N L N +TGN +NIL G A DT++ G G+D + D Sbjct: 4769 NALRNNITGNVANNILSGGADNDTIISGDGDDTLYGD 4805 Score = 89.0 bits (219), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 79/253 (31%), Positives = 116/253 (45%), Gaps = 73/253 (28%) Query: 145 QGGAGNDVLFATNGEEI-NGNGGDDVIYGGDGDDTLVGGTYSALARGETDND-------- 195 G GND L +G ++ NG G+D++ GG GDD + GG + + ++ ND Sbjct: 4281 NGEGGNDNLKGEDGNDVLNGGAGNDILDGGLGDDVMTGGVGNDIYYVDSSNDIIIDELNE 4340 Query: 196 -------------------------------------VLYGGAGKDSLNGGVGNDILDGG 218 ++ G + + L+GG +DIL GG Sbjct: 4341 GTDTVNTIITWTLGNHLENLTLIGSSAINGTGNALKNIIIGNSADNILSGGDNDDILRGG 4400 Query: 219 TGDDRMYGGAGDDIYVVDSAGDGVFENADAGRDTVLAGMSTTLGENVEDLRLLEGGSYNG 278 G+D +YGGAG+ DS G+ ++ G D G+ N Sbjct: 4401 EGNDTLYGGAGN-----DSLDGGIGNDSLNGED----------------------GNDNL 4433 Query: 279 TGNFLDNRLTGNSQDNILDGLAGADTMMGGQGNDRYFVDNVGDQVIEEAGEGIDTVYSTV 338 G+ ++ L GN+ ++ LDG G D M GG GND YFVD+ D +IEE EG DTV +++ Sbjct: 4434 KGDVGNDILNGNAGNDTLDGGLGDDVMTGGAGNDIYFVDSSNDTIIEELNEGTDTVNASI 4493 Query: 339 SMTLGANVENLTL 351 + TLG N+ENLTL Sbjct: 4494 NWTLGNNLENLTL 4506 >D7DJN9.1 D7DJN9_METS0 Hemolysin-type calcium-binding region Length = 1902 Score = 166 bits (420), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 171/465 (36%), Positives = 225/465 (48%), Gaps = 63/465 (13%) Query: 165 GGDDVIYGGDGDDTLVGGTYSALARGETDNDVLYGGAGKDSLNGGVGNDILDGGTGDDRM 224 GGDDVI G G+D L GG ND LYGG+G D+L+G GND+LDGGTGDD M Sbjct: 1066 GGDDVIDGEAGNDYLNGGD---------GNDTLYGGSGNDNLSGDTGNDVLDGGTGDDTM 1116 Query: 225 YGGAGDDIYVVDSAGDGVFENADAGRDTVLAGMST-----TLGENVEDLRLLEGGSYNGT 279 GG G+D Y +D D + EN + G D V ++T T+ NVE+ L+ +Y+ Sbjct: 1117 SGGEGNDTYTIDVLTDVITENLNEGTDLVNVAIATASGTYTVAANVENATLINTVAYSLI 1176 Query: 280 GNFLDNRLTGNSQDN---------ILDGLAGADTMMGGQGNDRYFVDNVGDQVIEEAGEG 330 GN LDN L GN+ N ILDG GADTM GG+GND Y VDNV D V E EG Sbjct: 1177 GNALDNILIGNAAVNTLNGDAGNDILDGGTGADTMKGGKGNDTYIVDNVADIVSENLDEG 1236 Query: 331 IDTVYSTVSMTLGANVENLTLMDARTPVHGEIYGQDALIYGTPKSYLMDYRQG-DARPGF 389 DTV S+ + L AN+ENLTL ++G D ++ G + ++ G D G Sbjct: 1237 TDTVQSSATYLLTANIENLTLT-GNVAINGVGNALDNIMIGNSANNTLNGAAGADTMIGG 1295 Query: 390 LGTCGVTSVANMLTMAGVNVTEKETLQRAIDRDWCDSDPSLPITLRGGVTCNDLAELMGS 449 LG T +MLT VTE L D ++ I GG +A + + Sbjct: 1296 LGND--TYTIDMLTDV---VTEN--LNEGTDL------VNVAIATTGGAYT--VAANVEN 1340 Query: 450 FGVAGEVDYRYDEARLVKLLKGGHVVTLCADAAVFRDMSGYLAGKRVGFHAVAVSGVACS 509 + V Y L +L G V A ++G LAG + G+ Sbjct: 1341 ATLTNTVTYSLTGNALDNILIGNAAVNTLNGGAGNDTLNG-LAGSD-----TMIGGLGND 1394 Query: 510 AKTGEVLGFYITDSGPGRYSEMNRFLSVG-DLRNMDAHESALIYS----VDPAKLLHRDS 564 T +VL IT++ L+ G DL N+ ++ Y+ V+ A L + + Sbjct: 1395 IYTIDVLTDVITEN-----------LNEGTDLVNVAIATASGTYTVAANVENATLTNTVA 1443 Query: 565 -SATGNELDNILMGNQDNNLLTGAKGNDTLTGQAGNDTYVFGKGD 608 S TGN LDN+L GN N L G GNDTL G AGNDT + G G+ Sbjct: 1444 YSLTGNVLDNVLTGNAAANTLDGGAGNDTLNGLAGNDTMIGGLGN 1488 Score = 141 bits (355), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 104/268 (38%), Positives = 137/268 (51%), Gaps = 56/268 (20%) Query: 145 QGGAGNDVLFATNGEE-INGNGGDDVIYGGDGDDTLVGG--------------------- 182 GG GND L+ +G + ++G+ G+DV+ GG GDDT+ GG Sbjct: 1081 NGGDGNDTLYGGSGNDNLSGDTGNDVLDGGTGDDTMSGGEGNDTYTIDVLTDVITENLNE 1140 Query: 183 --------------TYSALAR---------------GETDNDVLYGGAGKDSLNGGVGND 213 TY+ A G +++L G A ++LNG GND Sbjct: 1141 GTDLVNVAIATASGTYTVAANVENATLINTVAYSLIGNALDNILIGNAAVNTLNGDAGND 1200 Query: 214 ILDGGTGDDRMYGGAGDDIYVVDSAGDGVFENADAGRDTVLAGMSTTLGENVEDLRLLEG 273 ILDGGTG D M GG G+D Y+VD+ D V EN D G DTV + + L N+E+L L Sbjct: 1201 ILDGGTGADTMKGGKGNDTYIVDNVADIVSENLDEGTDTVQSSATYLLTANIENLTLTGN 1260 Query: 274 GSYNGTGNFLDNRLTGNSQDNILDGLAGADTMMGGQGNDRYFVDNVGDQVIEEAGEGIDT 333 + NG GN LDN + GNS +N L+G AGADTM+GG GND Y +D + D V E EG D Sbjct: 1261 VAINGVGNALDNIMIGNSANNTLNGAAGADTMIGGLGNDTYTIDMLTDVVTENLNEGTDL 1320 Query: 334 VYSTVSM-----TLGANVENLTLMDART 356 V ++ T+ ANVEN TL + T Sbjct: 1321 VNVAIATTGGAYTVAANVENATLTNTVT 1348 Score = 112 bits (280), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 80/191 (41%), Positives = 106/191 (55%), Gaps = 21/191 (10%) Query: 183 TYSALARGETDNDVLYGGAGKDSLNGGVGNDILDGGTGDDRMYGGAGDDIYVVDSAGDGV 242 TYS G +++L G A ++LNGG GND L+G G D M GG G+DIY +D D + Sbjct: 1348 TYSL--TGNALDNILIGNAAVNTLNGGAGNDTLNGLAGSDTMIGGLGNDIYTIDVLTDVI 1405 Query: 243 FENADAGRDTVLAGMST-----TLGENVEDLRLLEGGSYNGTGNFLDNRLTGNSQDNILD 297 EN + G D V ++T T+ NVE+ L +Y+ TGN LDN LTGN+ N LD Sbjct: 1406 TENLNEGTDLVNVAIATASGTYTVAANVENATLTNTVAYSLTGNVLDNVLTGNAAANTLD 1465 Query: 298 ---------GLAGADTMMGGQGNDRYFVDNVGDQVIEEAGEGIDTVYSTV-----SMTLG 343 GLAG DTM+GG GND Y +D + D V E EG D V + + T+ Sbjct: 1466 GGAGNDTLNGLAGNDTMIGGLGNDTYTIDALTDVVTENLNEGTDLVNVAIATASGTYTVA 1525 Query: 344 ANVENLTLMDA 354 ANVEN L+++ Sbjct: 1526 ANVENANLVNS 1536 Score = 111 bits (277), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 76/175 (43%), Positives = 104/175 (59%), Gaps = 18/175 (10%) Query: 195 DVLYGGAGKDSLNGGVGNDILDGGTGDDRMYGGAGDDIYVVDSAGDGVFENADAGRDTVL 254 +VL G A ++L+GG GND L+G G+D M GG G+D Y +D+ D V EN + G D V Sbjct: 1453 NVLTGNAAANTLDGGAGNDTLNGLAGNDTMIGGLGNDTYTIDALTDVVTENLNEGTDLVN 1512 Query: 255 AGMST-----TLGENVEDLRLLEGGSYNGTGNFLDNRLTGNSQDNILDGLAGAD------ 303 ++T T+ NVE+ L+ +Y +GN L+N LTGN+ N L+GLAG D Sbjct: 1513 VAIATASGTYTVAANVENANLVNSVAYTLSGNELNNVLTGNAYANTLNGLAGNDTLNGGA 1572 Query: 304 ---TMMGGQGNDRYFVDNVGDQVIE--EAGEGIDTVYSTVSMTLGA--NVENLTL 351 T++GG G+D Y VD D + E G G+DTV S+V+ LGA N+ENLTL Sbjct: 1573 GVDTLVGGDGDDTYIVDTTTDVITEADTVGAGVDTVQSSVTYVLGATSNLENLTL 1627 Score = 79.0 bits (193), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 81/227 (35%), Positives = 105/227 (46%), Gaps = 57/227 (25%) Query: 146 GGAGNDVLFATNGEEINGNGGDDVIYGGDGDDTLV------------------------- 180 GGAGND L NG G+D + GG G+DT Sbjct: 1466 GGAGNDTL--------NGLAGNDTMIGGLGNDTYTIDALTDVVTENLNEGTDLVNVAIAT 1517 Query: 181 -GGTYSALAR---------------GETDNDVLYGGAGKDSLNGGVGNDILDGGTGDDRM 224 GTY+ A G N+VL G A ++LNG GND L+GG G D + Sbjct: 1518 ASGTYTVAANVENANLVNSVAYTLSGNELNNVLTGNAYANTLNGLAGNDTLNGGAGVDTL 1577 Query: 225 YGGAGDDIYVVDSAGDGVFENAD---AGRDTVLAGMSTTLG--ENVEDLRLLEGGSYNGT 279 GG GDD Y+VD+ D + E AD AG DTV + ++ LG N+E+L L + N T Sbjct: 1578 VGGDGDDTYIVDTTTDVITE-ADTVGAGVDTVQSSVTYVLGATSNLENLTLTGTTAINAT 1636 Query: 280 GNFLDNRLTGNSQDN-ILDGLAGADTMMGGQGNDRYFVDNVGDQVIE 325 GN L N + GNS +N I D G D + GND F D VG+ + + Sbjct: 1637 GNALANFMKGNSANNTITDTAGGNDILQAFAGNDT-FNDTVGNNLFD 1682 Score = 68.2 bits (165), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 45/90 (50%), Positives = 54/90 (60%), Gaps = 10/90 (11%) Query: 165 GGDDVIYGGDGDDTLVGGTYSALARGETDNDVLYGGAGKDSLNGGVGNDILDGGTGDDRM 224 GGDDVI G G+D L GG ND LYGG+G D+L+G GND+LDGGTGDD M Sbjct: 884 GGDDVIDGEAGNDYLNGGD---------GNDTLYGGSGNDNLSGDTGNDVLDGGTGDDTM 934 Query: 225 YGGAGDDIYVVDS-AGDGVFENADAGRDTV 253 GG G D YVV + +G V N + + V Sbjct: 935 SGGEGSDTYVVRTGSGQDVINNINNSSEAV 964 >D0CEI3.1 D0CEI3_ACIBA Hemolysin-type calcium-binding region Length = 2890 Score = 160 bits (406), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 108/252 (42%), Positives = 145/252 (57%), Gaps = 46/252 (18%) Query: 146 GGAGNDVLFATNGEE-INGNGGDDVIYGGDGDDTLV------------------------ 180 G AGND+L+ G + +NG G+D +YGG GDDT + Sbjct: 2480 GQAGNDILYGQAGNDTLNGGTGNDTMYGGKGDDTYIVDSTADVISESVNEGTDIVQSSVT 2539 Query: 181 ------------GGTYSALARGETDNDVLYGGAGKDSLNGGVGNDILDGGTGDDRMYGGA 228 GT + G N+V+ G + ++L GGVG+D L+GG G D++ GG Sbjct: 2540 YTLLNNVENLTLTGTTAINGTGNALNNVIVGNSAINTLTGGVGDDYLNGGVGADKLLGGI 2599 Query: 229 GDDIYVVDSAGDGVFENADAGRDTVLAGMSTTLGENVEDLRLLEGGSYNGTGNFLDNRLT 288 G+D YV+D+ GD V ENA G DTVL+ ++ TLG N+E+L L+ + NGTGN L+N L Sbjct: 2600 GNDSYVIDNTGDIVTENAGEGIDTVLSSITYTLGNNLENLTLIGSTAINGTGNALNNVLV 2659 Query: 289 GNSQ---------DNILDGLAGADTMMGGQGNDRYFVDNVGDQVIEEAGEGIDTVYSTVS 339 GNS D+ LDG AGAD ++GG GND Y +DN GD V E AGEGIDTV S+++ Sbjct: 2660 GNSAINTLTAGVGDDYLDGGAGADKLLGGIGNDTYVIDNTGDIVTENAGEGIDTVLSSIT 2719 Query: 340 MTLGANVENLTL 351 TL +N+ENLTL Sbjct: 2720 YTLSSNLENLTL 2731 Score = 154 bits (388), Expect = 7e-35, Method: Compositional matrix adjust. Identities = 98/218 (44%), Positives = 129/218 (59%), Gaps = 28/218 (12%) Query: 152 VLFATNGEEINGNGGDDVIYGGDGDDTLVGGTYSALARGETDNDVLYGGAGKDSLNGGVG 211 ++F + ING D +YG G+DTL G + ND+LYG AG D+LNGG G Sbjct: 2451 LIFVVQNQTINGTSNADTLYGASGNDTLTG---------QAGNDILYGQAGNDTLNGGTG 2501 Query: 212 NDILDGGTGDDRMYGGAGDDIYVVDSAGDGVFENADAGRDTVLAGMSTTLGENVEDLRLL 271 ND MYGG GDD Y+VDS D + E+ + G D V + ++ TL NVE+L L Sbjct: 2502 ND---------TMYGGKGDDTYIVDSTADVISESVNEGTDIVQSSVTYTLLNNVENLTLT 2552 Query: 272 EGGSYNGTGNFLDNRLTGNSQ---------DNILDGLAGADTMMGGQGNDRYFVDNVGDQ 322 + NGTGN L+N + GNS D+ L+G GAD ++GG GND Y +DN GD Sbjct: 2553 GTTAINGTGNALNNVIVGNSAINTLTGGVGDDYLNGGVGADKLLGGIGNDSYVIDNTGDI 2612 Query: 323 VIEEAGEGIDTVYSTVSMTLGANVENLTLMDARTPVHG 360 V E AGEGIDTV S+++ TLG N+ENLTL+ T ++G Sbjct: 2613 VTENAGEGIDTVLSSITYTLGNNLENLTLI-GSTAING 2649 Score = 99.4 bits (246), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 65/136 (47%), Positives = 87/136 (63%), Gaps = 1/136 (0%) Query: 178 TLVGGTYSALARGETDNDVLYGGAGKDSLNGGVGNDILDGGTGDDRMYGGAGDDIYVVDS 237 TL+G T + G N+VL G + ++L GVG+D LDGG G D++ GG G+D YV+D+ Sbjct: 2640 TLIGST-AINGTGNALNNVLVGNSAINTLTAGVGDDYLDGGAGADKLLGGIGNDTYVIDN 2698 Query: 238 AGDGVFENADAGRDTVLAGMSTTLGENVEDLRLLEGGSYNGTGNFLDNRLTGNSQDNILD 297 GD V ENA G DTVL+ ++ TL N+E+L L + N TGN L+N LTGNS N L+ Sbjct: 2699 TGDIVTENAGEGIDTVLSSITYTLSSNLENLTLTGSTAINATGNTLNNTLTGNSGVNALN 2758 Query: 298 GLAGADTMMGGQGNDR 313 G AG D + G GND+ Sbjct: 2759 GGAGNDILDGQGGNDQ 2774 Score = 97.8 bits (242), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 84/235 (35%), Positives = 114/235 (48%), Gaps = 43/235 (18%) Query: 143 KNQGGAGNDVLFA---------TNGEEINGNGG------DDVIYGGDGDDTLVGGTYSAL 187 K GGAGNDV++ +N +N N DV+YGG+GDD + G Sbjct: 1852 KISGGAGNDVIYTYDPLSNNQISNSPYLNINLARNIYDIKDVVYGGEGDDYIYLGNQKTE 1911 Query: 188 ARGETDNDV------------LYGGAGKDSLNGGVGNDILDGGTGDDRMYGGAGDDIYVV 235 A G+ ND+ LYGG G D+L G G LDGG G D + GG+GDD ++V Sbjct: 1912 AYGDDGNDIIVSYSLSSNIQFLYGGDGNDTLKAGDGGAYLDGGAGTDHLVGGSGDDTFIV 1971 Query: 236 DSAGDGVFENADAGRDTVLAGMSTTLGEN-VEDLRLLEGGSYNGTGNFLDNRLTGNSQDN 294 D + + G DT+ + L +E + LL + + GN DN+L GN+ +N Sbjct: 1972 DEQDTYEENDPNGGYDTIHISQNIDLSLGYLEAVTLLGSQNLSIYGNTSDNKLIGNAGNN 2031 Query: 295 ILDGLAGADTMMGGQGNDRYFVDNV---------------GDQVIEEAGEGIDTV 334 +DG AG+D M GG GND Y VD GDQV+E+ GIDT+ Sbjct: 2032 YIDGRAGSDYMQGGLGNDYYVVDTTETIETDENGNTYFIEGDQVVEDVDGGIDTL 2086 Score = 75.1 bits (183), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 47/92 (51%), Positives = 59/92 (64%), Gaps = 3/92 (3%) Query: 150 NDVLFATNGEE-INGNGGDDVIYGGDGDDTLVGGTYSALARGETDNDVLYGGAGKDSLNG 208 ND L+ G + I G+GG D+IYGGDGDD LV + R +D LYGG GKDSL+G Sbjct: 1006 NDTLYGDAGNDNIRGDGGSDIIYGGDGDDFLVADVINN--RAFDGDDQLYGGNGKDSLSG 1063 Query: 209 GVGNDILDGGTGDDRMYGGAGDDIYVVDSAGD 240 GND LDGG GDD ++GG GDD ++ + D Sbjct: 1064 FDGNDTLDGGAGDDIIFGGKGDDYFISNEGND 1095 Score = 75.1 bits (183), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 80/239 (33%), Positives = 104/239 (43%), Gaps = 66/239 (27%) Query: 146 GGAGNDVLFATNG-EEINGNGGDDVIYGGDGDDTLV------------GGTYSALARGE- 191 GG GND L A +G ++G G D + GG GDDT + G Y + + Sbjct: 1935 GGDGNDTLKAGDGGAYLDGGAGTDHLVGGSGDDTFIVDEQDTYEENDPNGGYDTIHISQN 1994 Query: 192 ---------------TDNDVLYGGAGKDSLNGGVGNDILDGGTGDDRMYGGAGDDIYVVD 236 + N +YG + L G GN+ +DG G D M GG G+D YVVD Sbjct: 1995 IDLSLGYLEAVTLLGSQNLSIYGNTSDNKLIGNAGNNYIDGRAGSDYMQGGLGNDYYVVD 2054 Query: 237 SA---------------GDGVFENADAGRDT------------------VLAGMSTTLGE 263 + GD V E+ D G DT VL L Sbjct: 2055 TTETIETDENGNTYFIEGDQVVEDVDGGIDTLERWEDARFISQDENGNPVLTDSYKILEN 2114 Query: 264 NVEDLRLLEGGSYNGTGNFLDNRLTGNSQDNILDGLAGADTMMG--GQGNDRY-FVDNV 319 N+E+L +L+G + G GN LDN + GN QDN +DGLAG DT + G G D Y F DN+ Sbjct: 2115 NIENL-ILKGNAKTGFGNDLDNIIVGNEQDNYIDGLAGNDTYIFSRGGGTDTYSFEDNI 2172 Score = 68.6 bits (166), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 43/87 (49%), Positives = 57/87 (65%), Gaps = 1/87 (1%) Query: 146 GGAGNDVLFATNGE-EINGNGGDDVIYGGDGDDTLVGGTYSALARGETDNDVLYGGAGKD 204 GG GND LF +GE ++ G GDDVI G+G+D L+GGT + G ND L GG G D Sbjct: 1350 GGEGNDQLFGGDGEDQLEGGNGDDVIDSGEGNDQLIGGTGNDRLLGGEGNDQLQGGEGDD 1409 Query: 205 SLNGGVGNDILDGGTGDDRMYGGAGDD 231 L GND ++GGTG+D++ GG+G+D Sbjct: 1410 YLEASNGNDFIEGGTGNDQLIGGSGED 1436