BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0030.p (220 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IYS5.1 D8IYS5_HERSS Signal transduction histidine kinase prote... 401 e-110 F1VWU8.1 F1VWU8_9BURK Putative uncharacterized protein 121 7e-26 D7DPX5.1 D7DPX5_METS0 PAS/PAC sensor signal transduction histidi... 119 3e-25 C6WV68.1 C6WV68_METML PAS/PAC sensor signal transduction histidi... 119 4e-25 A4G677.1 A4G677_HERAR Putative signal transduction histidine kinase 119 4e-25 Q1GZT2.1 Q1GZT2_METFK Putative signal transduction histidine kinase 117 1e-24 B9TG52.1 B9TG52_RICCO Putative uncharacterized protein 117 2e-24 A6SXZ6.1 A6SXZ6_JANMA Two-component sensor histidine kinase 116 3e-24 E8YVG7.1 E8YVG7_9BURK Multi-sensor signal transduction histidine... 113 1e-23 E4QKI6.1 E4QKI6_METS6 PAS/PAC sensor signal transduction histidi... 112 3e-23 >D8IYS5.1 D8IYS5_HERSS Signal transduction histidine kinase protein EC=2.7.3.- Length = 356 Score = 401 bits (1030), Expect = e-110, Method: Compositional matrix adjust. Identities = 215/220 (97%), Positives = 215/220 (97%) Query: 1 MSHPLPPPATAIHIREQERERIARDLHDDLGGVLAGVGMALGRLQEQLAAQGLAAPLAEA 60 MSHPLPPPATAIHIREQERERIARDLHDDLGGVLAGVGMALGRLQEQLAAQGLAAPLAEA Sbjct: 137 MSHPLPPPATAIHIREQERERIARDLHDDLGGVLAGVGMALGRLQEQLAAQGLAAPLAEA 196 Query: 61 DEARQLLQQAMASMHDIIDELHPPIVEFGLVDALQWQCRQIQREYRLHCQLDCPPALEQE 120 DEARQLLQQAMASMH IIDELHPPIVEFGLVDALQWQCRQIQREYRLHCQLDCPP LEQE Sbjct: 197 DEARQLLQQAMASMHSIIDELHPPIVEFGLVDALQWQCRQIQREYRLHCQLDCPPTLEQE 256 Query: 121 DRFLILGLLRILREAASNAARHGRASALRVGLRMRQARLEMQIADDGCGIAPLHAKEDAT 180 DRFLILGLLRILREAASNAARHGRASALRV LRMRQARLEMQIADDGCGIAPLHAKE A Sbjct: 257 DRFLILGLLRILREAASNAARHGRASALRVDLRMRQARLEMQIADDGCGIAPLHAKEVAP 316 Query: 181 RHGHGLRNMRERAQALGGELFIEAGQDGGVVIRTLIPVAR 220 RHGHGLRNMRERAQALGGELFIEAGQDGGVVIRTLIPVAR Sbjct: 317 RHGHGLRNMRERAQALGGELFIEAGQDGGVVIRTLIPVAR 356 >F1VWU8.1 F1VWU8_9BURK Putative uncharacterized protein Length = 446 Score = 121 bits (303), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 75/212 (35%), Positives = 119/212 (56%), Gaps = 19/212 (8%) Query: 14 IREQERERIARDLHDDLGGVLAGVGMALGRLQEQLAAQGLAAPLAEADEARQLLQQAMAS 73 ++E+ER RIAR++HDD GG L + MAL L+ +L A +AD L+ + + S Sbjct: 227 VKEEERTRIAREIHDDRGGNLTAIKMALALLRRRLPDD--PALTDKADYVDSLVDRTIES 284 Query: 74 MHDIIDELHPPIVEFGLVDALQWQCRQIQREYRLHCQ-------LDCPPALEQEDRFLIL 126 +H I +L P I++FG+V A++WQ + +++ + C +D PP EQ Sbjct: 285 IHRISVDLRPSILDFGIVAAIEWQAAEFEKQLGIPCHVASSDSDIDLPP--EQAS----- 337 Query: 127 GLLRILREAASNAARHGRASALRVGLRMRQARLEMQIADDGCGIAPLHAKEDATRHGHGL 186 L RI +E+ +N ++H RAS+++V L Q + M+I+D+G GIA A++ G+ Sbjct: 338 ALFRIFQESLNNISKHARASSVQVRLNRNQRGIRMEISDNGTGIA---ARDRQKPASFGI 394 Query: 187 RNMRERAQALGGELFIEAGQDGGVVIRTLIPV 218 R M ERA ALGG L + GG ++ IP+ Sbjct: 395 RGMIERANALGGSLSVSNLPKGGSMVAIRIPL 426 >D7DPX5.1 D7DPX5_METS0 PAS/PAC sensor signal transduction histidine kinase EC=2.7.13.3 Length = 485 Score = 119 bits (298), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 64/205 (31%), Positives = 107/205 (52%), Gaps = 4/205 (1%) Query: 14 IREQERERIARDLHDDLGGVLAGVGMALGRLQEQLAAQGLAAPLAEADEARQLLQQAMAS 73 I+EQER IAR++HDDLGG L + M L + +L+ +G + +A +L + Sbjct: 284 IKEQERSAIAREIHDDLGGNLTAIKMGLSSIINKLS-KGQDVTIEQAQGLESILDSTFEA 342 Query: 74 MHDIIDELHPPIVEFGLVDALQWQCRQIQREYRLHCQLDCPPALEQEDRFLILGLLRILR 133 +H I +L P +++ G+V AL+WQ ++ +++ + C+ C + + L RI + Sbjct: 343 VHRISSDLRPNVLDLGIVAALEWQAKEFEKQLGITCKFTCNQSEISVTTDQGITLFRIFQ 402 Query: 134 EAASNAARHGRASALRVGLRMRQARLEMQIADDGCGIAPLHAKEDATRHGHGLRNMRERA 193 E+ SN A+H +A+ + V L + + I D+G GI + + + GLR MRER Sbjct: 403 ESMSNIAKHAKATHVSVDLSAFAHDIILTINDNGVGIK---SSDTLKSNSFGLRGMRERV 459 Query: 194 QALGGELFIEAGQDGGVVIRTLIPV 218 AL G ++ G VI +PV Sbjct: 460 TALHGTFAVQQSNKQGTVITIKLPV 484 >C6WV68.1 C6WV68_METML PAS/PAC sensor signal transduction histidine kinase EC=2.7.13.3 Length = 499 Score = 119 bits (297), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 71/211 (33%), Positives = 112/211 (53%), Gaps = 16/211 (7%) Query: 14 IREQERERIARDLHDDLGGVLAGVGMALGRLQEQLAAQGLAAPLAEADEARQLLQQAMAS 73 I+E ER RIAR++HDDLGG L + + L + ++A GL +A ++ + Sbjct: 298 IKELERTRIAREIHDDLGGNLTAIKIGLTSIINRIAT-GLPVSFEQAKGLESIVDNTFEA 356 Query: 74 MHDIIDELHPPIVEFGLVDALQWQCRQIQREYRLHCQLDCPPALEQEDRFLI----LGLL 129 +H I +L P I++ G+V AL+WQ ++ +++ + C Q D + + L Sbjct: 357 IHKISSDLRPNILDLGIVAALEWQAKEFEKQVGVTCTFTT----NQADIVVTPDQAITLF 412 Query: 130 RILREAASNAARHGRASALRVGLRMRQARLEMQIADDGCGIAPLHAKEDATRHGHGLRNM 189 RI +E+ SN A+H ASA+ V L + + M+I+D+G GI + + + GLR M Sbjct: 413 RICQESMSNIAKHANASAVHVDLNLHYGEIIMKISDNGIGI---NTADTYKPNSFGLRGM 469 Query: 190 RERAQALGGELFIE--AGQDGGVVIRTLIPV 218 +ER AL G IE AGQ G VI +P+ Sbjct: 470 QERVAALYGSFDIEQLAGQ--GTVIAVTLPI 498 >A4G677.1 A4G677_HERAR Putative signal transduction histidine kinase Length = 478 Score = 119 bits (297), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 70/210 (33%), Positives = 112/210 (53%), Gaps = 14/210 (6%) Query: 14 IREQERERIARDLHDDLGGVLAGVGMALGRLQEQLAAQGLAAPLAEADEARQLLQQAMAS 73 ++EQER IAR++HDDLGG L + MAL L +L + + + +AD L+ + + S Sbjct: 274 VKEQERTHIAREIHDDLGGNLTAIKMALALLTRRLPRKNVEL-IEKADYVESLVDRTIES 332 Query: 74 MHDIIDELHPPIVEFGLVDALQWQCRQIQREYRLHCQLDCPP-----ALEQEDRFLILGL 128 +H I L P I++FGLV A+ WQ R+ +++ + CQ AL+Q L Sbjct: 333 VHRIAGNLRPGILDFGLVAAIDWQGREFEKQVGIPCQFSSNKTEIDLALDQAT-----AL 387 Query: 129 LRILREAASNAARHGRASALRVGLRMRQARLEMQIADDGCGIAPLHAKEDATRHGHGLRN 188 RI +EA +N A+H +AS + V L + + ++I D+G GI + G+R Sbjct: 388 FRIFQEALTNIAKHAKASLVTVQLVHTRQYVRLEIVDNGRGI---QMTDRNKPKSFGIRG 444 Query: 189 MRERAQALGGELFIEAGQDGGVVIRTLIPV 218 M ER+ A+GG L + GG ++ +P+ Sbjct: 445 MVERSIAMGGSLSVSTAPKGGTIVAINVPL 474 >Q1GZT2.1 Q1GZT2_METFK Putative signal transduction histidine kinase Length = 479 Score = 117 bits (293), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 67/206 (32%), Positives = 112/206 (54%), Gaps = 4/206 (1%) Query: 13 HIREQERERIARDLHDDLGGVLAGVGMALGRLQEQLAAQGLAAPLAEADEARQLLQQAMA 72 I+E+ER +IA+++HDDLGG L + + L + ++L + LA+A + ++ Sbjct: 268 QIKEKERLKIAQEVHDDLGGNLTAIRLGLSSMIKRLGPEQ-EVLLAKARQLEAIVDDTFE 326 Query: 73 SMHDIIDELHPPIVEFGLVDALQWQCRQIQREYRLHCQLDCPPALEQEDRFLILGLLRIL 132 + H I +L P ++E G+V AL+WQ Q + + C+ C A + L RI Sbjct: 327 AAHRIASDLRPNVLELGIVAALEWQATQFVDKIGIPCEFVCNVAEVDISTDHAITLFRIC 386 Query: 133 REAASNAARHGRASALRVGLRMRQARLEMQIADDGCGIAPLHAKEDATRHGHGLRNMRER 192 +EA SN A++ +AS + V L + MQ+ DDG GIAP+ + + G+ M ER Sbjct: 387 QEAMSNIAKYAKASHVEVTLEASAEEIMMQVIDDGIGIAPV---DRLKANAFGISGMSER 443 Query: 193 AQALGGELFIEAGQDGGVVIRTLIPV 218 A AL G+ ++AG+ GG ++ +P+ Sbjct: 444 AVALAGQCKVQAGRQGGTIVSVTLPL 469 >B9TG52.1 B9TG52_RICCO Putative uncharacterized protein Length = 335 Score = 117 bits (292), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 78/216 (36%), Positives = 116/216 (53%), Gaps = 20/216 (9%) Query: 12 IH-IREQERERIARDLHDDLGGVLAGVGMALGRLQEQLAAQGLAAPLAEADEARQLLQQA 70 IH ++EQER IAR++HDDLGG L + + L + +Q+ + +A + ++ Q Sbjct: 126 IHQVKEQERVSIAREIHDDLGGNLTAMKLGLSTIIQQIE-DSQQVNMEQATMLQAIINQT 184 Query: 71 MASMHDIIDELHPPIVEFGLVDALQWQCRQIQRE------YRLHCQ-LDCPPALEQEDRF 123 ++H I L P I++ GLVDAL+WQ Q +++ + +C L+C P +Q Sbjct: 185 FDAVHRISGNLRPNILDLGLVDALEWQVSQFKKQLGITARFVTNCHDLECDP--DQS--- 239 Query: 124 LILGLLRILREAASNAARHGRASALRVGLRMRQARLEMQIADDGCGIAPLHAKEDATRHG 183 + L RI +EA SN A++ +A + V L + L M I+D+G GIAP + + Sbjct: 240 --MALFRICQEALSNIAKYAQADLVSVELSLVDQALFMTISDNGVGIAP---ADKIKPNS 294 Query: 184 HGLRNMRERAQALGGELFIEAGQDG-GVVIRTLIPV 218 GLR M+ERA ALGGE IEA G G I P Sbjct: 295 FGLRGMQERAAALGGECHIEASSSGPGTCIHVRAPF 330 >A6SXZ6.1 A6SXZ6_JANMA Two-component sensor histidine kinase Length = 490 Score = 116 bits (290), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 68/205 (33%), Positives = 111/205 (54%), Gaps = 4/205 (1%) Query: 14 IREQERERIARDLHDDLGGVLAGVGMALGRLQEQLAAQGLAAPLAEADEARQLLQQAMAS 73 ++E+ER RIAR++HDDLGG L + MAL L +L + + L +A L+ + + + Sbjct: 274 VKEKERTRIAREIHDDLGGNLTAIKMALALLTRRLPGKS-SELLEKAAYVESLVDRTIET 332 Query: 74 MHDIIDELHPPIVEFGLVDALQWQCRQIQREYRLHCQLDCPPALEQEDRFLILGLLRILR 133 +H I +L P I++FGLV A+ WQ ++ +++ + C+ A D L RI + Sbjct: 333 VHRIAGDLRPGILDFGLVAAIDWQSKEFEKQLGIPCEFVSNQAEIDLDLDQATALFRIFQ 392 Query: 134 EAASNAARHGRASALRVGLRMRQARLEMQIADDGCGIAPLHAKEDATRHGHGLRNMRERA 193 EA +N A+H +AS + V L + ++I D+G GI + A G+R M ER+ Sbjct: 393 EALTNIAKHAQASLVSVQLMHTPQYVRLEIIDNGRGI---ELADRAKPKSFGIRGMVERS 449 Query: 194 QALGGELFIEAGQDGGVVIRTLIPV 218 A+GG L + GG V+ +P+ Sbjct: 450 VAMGGSLSVSTAPKGGTVVAINLPL 474 >E8YVG7.1 E8YVG7_9BURK Multi-sensor signal transduction histidine kinase Length = 610 Score = 113 bits (283), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 73/212 (34%), Positives = 114/212 (53%), Gaps = 17/212 (8%) Query: 14 IREQERERIARDLHDDLGGVLAGVGMALGRLQEQLA----AQGLAAPLAEADEARQLLQQ 69 IRE+ER+RIA ++HD+LG +L + + + LQ +LA AQG + D R+L+++ Sbjct: 400 IREEERKRIALEVHDELGQLLTALKIDISLLQMRLAGNPEAQG------KTDAMRELIER 453 Query: 70 AMASMHDIIDELHPPIVEFGLVDALQWQCRQIQREYRLHCQLDC---PPALEQEDRFLIL 126 M + ++ + L P + FGLV AL+W + Y + C + P LE Sbjct: 454 TMWMVRNVANHLRPAALNFGLVSALEWLAQDFNARYYIQCTVVTHGDEPVLEDAR---AT 510 Query: 127 GLLRILREAASNAARHGRASALRVGLRMRQARLEMQIADDGCGIAPLHAKEDATRHGHGL 186 + RI +E+ +N ARH RAS + + LR + ++++I DDGCG A R +GL Sbjct: 511 AIFRIAQESLTNVARHARASHVVLTLRSGEGFIDLEIRDDGCGF-DRDAVSARQRGSYGL 569 Query: 187 RNMRERAQALGGELFIEAGQDGGVVIRTLIPV 218 M ERA+ +GG L I +G G V+ IP+ Sbjct: 570 LGMAERARLIGGALTITSGASTGTVVALRIPL 601 >E4QKI6.1 E4QKI6_METS6 PAS/PAC sensor signal transduction histidine kinase Length = 465 Score = 112 bits (281), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 67/205 (32%), Positives = 107/205 (52%), Gaps = 4/205 (1%) Query: 13 HIREQERERIARDLHDDLGGVLAGVGMALGRLQEQLAAQGLAAPLAEADEARQLLQQAMA 72 ++EQER RIAR++HDDLGG L + + L + +++ + +A ++ + Sbjct: 261 QVKEQERRRIAREIHDDLGGNLTAIKIGLTSIIKRINPDE-PKLVEKAHNLESIVDRTFD 319 Query: 73 SMHDIIDELHPPIVEFGLVDALQWQCRQIQREYRLHCQLDCPPALEQEDRFLILGLLRIL 132 +H I +L P ++E G+V AL+WQC Q ++++ L C+ + L RI Sbjct: 320 IVHRIASDLRPDVLELGIVAALEWQCGQFEKQFSLPCRFYSSQTELAVSADEAITLFRIC 379 Query: 133 REAASNAARHGRASALRVGLRMRQARLEMQIADDGCGIAPLHAKEDATRHGHGLRNMRER 192 +EA SN A+H RA + V L + + ++I DDG GI ++ + GLR MRER Sbjct: 380 QEAMSNIAKHARARQVEVELLVEDRDIMLRIVDDGQGI---RMQDQHKSNSFGLRGMRER 436 Query: 193 AQALGGELFIEAGQDGGVVIRTLIP 217 AL G L +E GG ++ IP Sbjct: 437 VAALDGSLEVEKRVRGGTAVQVKIP 461