BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0047.p (281 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8ITV5.1 D8ITV5_HERSS Permease of the drug/metabolite transporte... 534 e-150 A6SUZ7.1 A6SUZ7_JANMA Transporter of the DMT superfamily 355 6e-96 C6BJY5.1 C6BJY5_RALP1 Putative uncharacterized protein 296 2e-78 B2U8D0.1 B2U8D0_RALPJ Putative uncharacterized protein 280 1e-73 E2T1K4.1 E2T1K4_9RALS Integral membrane protein DUF6 280 1e-73 E2XRM9.1 E2XRM9_PSEFL Putative uncharacterized protein 247 1e-63 C3KCD1.1 C3KCD1_PSEFS Putative membrane protein 246 3e-63 A4WB79.1 A4WB79_ENT38 Putative uncharacterized protein 242 5e-62 E8Y160.1 E8Y160_RAHSY Putative uncharacterized protein 240 2e-61 D4E4F7.1 D4E4F7_SEROD Integral membrane protein 238 6e-61 >D8ITV5.1 D8ITV5_HERSS Permease of the drug/metabolite transporter (DMT) superfamily protein Length = 281 Score = 534 bits (1376), Expect = e-150, Method: Compositional matrix adjust. Identities = 280/281 (99%), Positives = 280/281 (99%) Query: 1 MNIAVIALVLAAALLHASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWF 60 MNIAVIALVLAAALLHASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWF Sbjct: 1 MNIAVIALVLAAALLHASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWF 60 Query: 61 YIILSGLLHTGYNLFLIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGI 120 YIILSGLLHTGYNLFLIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGI Sbjct: 61 YIILSGLLHTGYNLFLIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGI 120 Query: 121 LLVSLGIVSLADLRAMRSREHLAGPLAAFATGAFIAAYTITDGIGARLAGDAMSYAGWLF 180 LLVSLGIVSLADLRAMRSREHLAGPLAAFATGAFIAAYTITDGIGARLAGDAMSYAGWLF Sbjct: 121 LLVSLGIVSLADLRAMRSREHLAGPLAAFATGAFIAAYTITDGIGARLAGDAMSYAGWLF 180 Query: 181 VLDSIALAVIYQRRHGRWPIALGRRETWIGLGGGVMSLLAYGIVIWAVTLAPMGMVSALR 240 VLDSIALAVIYQRRHGRWPIALGRRETW GLGGGVMSLLAYGIVIWAVTLAPMGMVSALR Sbjct: 181 VLDSIALAVIYQRRHGRWPIALGRRETWTGLGGGVMSLLAYGIVIWAVTLAPMGMVSALR 240 Query: 241 ETSVLFALLIGALFLGERLTLRRVLSGVVIVAGTIVLGTHH 281 ETSVLFALLIGALFLGERLTLRRVLSGVVIVAGTIVLGTHH Sbjct: 241 ETSVLFALLIGALFLGERLTLRRVLSGVVIVAGTIVLGTHH 281 >A6SUZ7.1 A6SUZ7_JANMA Transporter of the DMT superfamily Length = 298 Score = 355 bits (910), Expect = 6e-96, Method: Compositional matrix adjust. Identities = 194/280 (69%), Positives = 234/280 (83%), Gaps = 3/280 (1%) Query: 1 MNIAVIALVLAAALLHASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWF 60 M+I V++LVL AALLHASWNALLKSS D L +LA+MT+G+G+ A+PLIL+ P P P SW Sbjct: 21 MSIFVLSLVLFAALLHASWNALLKSSADPLGALAVMTIGSGLAALPLILYLPLPLPESWP 80 Query: 61 YIILSGLLHTGYNLFLIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGI 120 YI LS +LHT YNLFLIRAYRIGDF QSYPIARGSSPLLV LGAA+ GEQ+ T++G+ Sbjct: 81 YIALSAVLHTAYNLFLIRAYRIGDFSQSYPIARGSSPLLVTLGAALLVGEQMSWMTLLGV 140 Query: 121 LLVSLGIVSLADLRAMRSREHLAGPLAAFATGAFIAAYTITDGIGARLAGDAMSYAGWLF 180 +L+S+GI+SLA ++ +R HLAGP+AAF TGAFIAAYTITDG+GAR+AG A+SY GWLF Sbjct: 141 ILISVGIISLAHIK---NRLHLAGPIAAFTTGAFIAAYTITDGLGARVAGSALSYCGWLF 197 Query: 181 VLDSIALAVIYQRRHGRWPIALGRRETWIGLGGGVMSLLAYGIVIWAVTLAPMGMVSALR 240 VLDS+ L +IY R H R P+A G +ETW+ LGGG+MSLLAYGIVIWAVTLAPMG VSALR Sbjct: 198 VLDSVPLLLIYLRLHKRLPMAFGSKETWVALGGGLMSLLAYGIVIWAVTLAPMGTVSALR 257 Query: 241 ETSVLFALLIGALFLGERLTLRRVLSGVVIVAGTIVLGTH 280 ETSVLFA LIG LFLGE+L++RR+LS ++I G I+LG H Sbjct: 258 ETSVLFAALIGWLFLGEKLSMRRILSCLLITVGAIILGLH 297 >C6BJY5.1 C6BJY5_RALP1 Putative uncharacterized protein Length = 277 Score = 296 bits (758), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 164/278 (58%), Positives = 200/278 (71%), Gaps = 4/278 (1%) Query: 1 MNIAVIALVLAAALLHASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWF 60 M AVIALVL AALLHASWNALLKS DRL ++ LMTL +G+ A+P+ + P P PA+W Sbjct: 1 MTPAVIALVLCAALLHASWNALLKSGADRLRAITLMTLASGVAALPMAIALPLPAPAAWP 60 Query: 61 YIILSGLLHTGYNLFLIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGI 120 Y+ LS +LH GYN+FL RAYR G+FGQ YPIARGSSPLLV +GAA+FAGE G+ + G+ Sbjct: 61 YVALSAVLHVGYNVFLARAYRFGEFGQVYPIARGSSPLLVTVGAALFAGEMPGVIALTGV 120 Query: 121 LLVSLGIVSLADLRAMRSREHLAGPLAAFATGAFIAAYTITDGIGARLAGDAMSYAGWLF 180 +LVS GI+SLA R + L LAA TG FIA YT+ DGIGAR+AG+A +Y+ WLF Sbjct: 121 VLVSGGILSLARGR----KADLGSTLAALTTGVFIACYTVCDGIGARVAGNANAYSAWLF 176 Query: 181 VLDSIALAVIYQRRHGRWPIALGRRETWIGLGGGVMSLLAYGIVIWAVTLAPMGMVSALR 240 +LD + + ++Y+ G I L T GGGV+SL+AYGIVIWAVTLAPMG VSALR Sbjct: 177 MLDGLPMVLLYRVWKGPLNIGLRDVNTLKTFGGGVVSLVAYGIVIWAVTLAPMGPVSALR 236 Query: 241 ETSVLFALLIGALFLGERLTLRRVLSGVVIVAGTIVLG 278 ETSV+FA L+G LFL E LT RRV + VI G LG Sbjct: 237 ETSVVFAALLGRLFLKESLTARRVSACSVIAFGAYCLG 274 >B2U8D0.1 B2U8D0_RALPJ Putative uncharacterized protein Length = 277 Score = 280 bits (717), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 163/278 (58%), Positives = 200/278 (71%), Gaps = 4/278 (1%) Query: 1 MNIAVIALVLAAALLHASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWF 60 M AVIALVL AALLHASWNALLKS DRL ++ LMTL +G+ A+P+ + P P PA+W Sbjct: 1 MTPAVIALVLCAALLHASWNALLKSGSDRLRAITLMTLASGVAALPMAIALPLPAPAAWP 60 Query: 61 YIILSGLLHTGYNLFLIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGI 120 Y+ LS +LH GYN+FL RAYR G+FGQ YPIARGSSPLLV +GA++FAGE G+ T+ G+ Sbjct: 61 YVALSAVLHVGYNVFLARAYRFGEFGQVYPIARGSSPLLVTVGASLFAGEMPGVITLAGV 120 Query: 121 LLVSLGIVSLADLRAMRSREHLAGPLAAFATGAFIAAYTITDGIGARLAGDAMSYAGWLF 180 +LVS GI+SLA R + L LAA TG FIA YT+ DGIGAR AG+A +Y+ WLF Sbjct: 121 VLVSGGILSLARGR----KADLGSTLAALTTGVFIACYTVCDGIGARAAGNANAYSAWLF 176 Query: 181 VLDSIALAVIYQRRHGRWPIALGRRETWIGLGGGVMSLLAYGIVIWAVTLAPMGMVSALR 240 +LD + + ++Y+ G I L T GGGV+SL+AYGIVIWAVTLAPMG VSALR Sbjct: 177 MLDGLPMVLLYRVWKGPLNIDLRDANTLKTFGGGVVSLIAYGIVIWAVTLAPMGPVSALR 236 Query: 241 ETSVLFALLIGALFLGERLTLRRVLSGVVIVAGTIVLG 278 ETSV+FA L+G LFL E LT RR+ + VI G LG Sbjct: 237 ETSVVFAALLGRLFLKESLTARRLSACSVIAFGAYCLG 274 >E2T1K4.1 E2T1K4_9RALS Integral membrane protein DUF6 Length = 277 Score = 280 bits (717), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 163/278 (58%), Positives = 200/278 (71%), Gaps = 4/278 (1%) Query: 1 MNIAVIALVLAAALLHASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWF 60 M AVIALVL AALLHASWNALLKS DRL ++ LMTL +G+ A+P+ + P P PA+W Sbjct: 1 MTPAVIALVLCAALLHASWNALLKSGSDRLRAITLMTLASGVAALPMAIALPLPAPAAWP 60 Query: 61 YIILSGLLHTGYNLFLIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGI 120 Y+ LS +LH GYN+FL RAYR G+FGQ YPIARGSSPLLV +GA++FAGE G+ T+ G+ Sbjct: 61 YVALSAVLHVGYNVFLARAYRFGEFGQVYPIARGSSPLLVTVGASLFAGEMPGVITLAGV 120 Query: 121 LLVSLGIVSLADLRAMRSREHLAGPLAAFATGAFIAAYTITDGIGARLAGDAMSYAGWLF 180 +LVS GI+SLA R + L LAA TG FIA YT+ DGIGAR AG+A +Y+ WLF Sbjct: 121 VLVSGGILSLARGR----KADLGSTLAALTTGVFIACYTVCDGIGARAAGNANAYSAWLF 176 Query: 181 VLDSIALAVIYQRRHGRWPIALGRRETWIGLGGGVMSLLAYGIVIWAVTLAPMGMVSALR 240 +LD + + ++Y+ G I L T GGGV+SL+AYGIVIWAVTLAPMG VSALR Sbjct: 177 MLDGLPMVLLYRVWKGPLNIDLRDANTLKTFGGGVVSLIAYGIVIWAVTLAPMGPVSALR 236 Query: 241 ETSVLFALLIGALFLGERLTLRRVLSGVVIVAGTIVLG 278 ETSV+FA L+G LFL E LT RR+ + VI G LG Sbjct: 237 ETSVVFAALLGRLFLKESLTARRLSACSVIAFGAYCLG 274 >E2XRM9.1 E2XRM9_PSEFL Putative uncharacterized protein Length = 275 Score = 247 bits (631), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 146/280 (52%), Positives = 193/280 (68%), Gaps = 7/280 (2%) Query: 1 MNIAVIALVLAAALLHASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWF 60 M I ++ LVL AALLHASWNALL+ DRL S+ +M + + + + P P SW Sbjct: 1 MPIHLVVLVLFAALLHASWNALLRGGADRLWSMTVMCIAIAVTCVLAATFMVRPAPESWG 60 Query: 61 YIILSGLLHTGYNLFLIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGI 120 Y +LSGLLH GYNLFL+R+YR+GD GQ YPI+RGSSP+L+ LGAA FAGE++ ++GI Sbjct: 61 YALLSGLLHVGYNLFLVRSYRVGDLGQIYPISRGSSPVLITLGAAAFAGERIAPGELLGI 120 Query: 121 LLVSLGIVSLADLRAMRSREHLAGPLAAFA--TGAFIAAYTITDGIGARLAGDAMSYAGW 178 LVS GI+SL A R R L+ P FA TG FIAAY++ DGIGARL+G ++Y W Sbjct: 121 ALVSGGIISL----AFRGRS-LSVPSLPFALGTGVFIAAYSVVDGIGARLSGAPLAYTVW 175 Query: 179 LFVLDSIALAVIYQRRHGRWPIALGRRETWIGLGGGVMSLLAYGIVIWAVTLAPMGMVSA 238 + L + + V+Y + R + GG++SLLAYG+VI+A+ AP+G VSA Sbjct: 176 MCALWGVLMPVVYIGLRDARSLFCVRPGAVSAVVGGLVSLLAYGVVIYAMNEAPLGAVSA 235 Query: 239 LRETSVLFALLIGALFLGERLTLRRVLSGVVIVAGTIVLG 278 LRETSVLFA+LIG LFLGE LT+RR+L+ VVIV+GT+++G Sbjct: 236 LRETSVLFAVLIGYLFLGETLTVRRILACVVIVSGTLLIG 275 >C3KCD1.1 C3KCD1_PSEFS Putative membrane protein Length = 275 Score = 246 bits (628), Expect = 3e-63, Method: Compositional matrix adjust. Identities = 141/280 (50%), Positives = 188/280 (67%), Gaps = 7/280 (2%) Query: 1 MNIAVIALVLAAALLHASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWF 60 M ++ L+L AALLHASWNALL++ DRL S+ +M L + + + L+ P ASW Sbjct: 1 MPFPIVLLILFAALLHASWNALLRAGTDRLWSMTVMCLAVAVASTVIALFLTPPAAASWP 60 Query: 61 YIILSGLLHTGYNLFLIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGI 120 Y +LSG+LH GYNLFL+R+Y++GD GQ+YPIARGSSP+L+ L A FA E + +IGI Sbjct: 61 YAVLSGVLHVGYNLFLVRSYKVGDLGQTYPIARGSSPILITLFAFAFAEETVNAGALIGI 120 Query: 121 LLVSLGIVSLADLRAMRSREHLAGPLAAFA--TGAFIAAYTITDGIGARLAGDAMSYAGW 178 +LVS GI+SL + LA P +A TG FIAAY++TDGIGARL+ ++Y W Sbjct: 121 VLVSAGIISLT-----FKQRRLAVPSLPYALGTGVFIAAYSVTDGIGARLSDAPLAYTAW 175 Query: 179 LFVLDSIALAVIYQRRHGRWPIALGRRETWIGLGGGVMSLLAYGIVIWAVTLAPMGMVSA 238 + L I + ++Y G + R GG++SLLAYGIVI+A++ APMG VSA Sbjct: 176 MCALWGIMMPLVYVGLRGTRSLLTPRPGCITAFLGGLVSLLAYGIVIYAMSEAPMGAVSA 235 Query: 239 LRETSVLFALLIGALFLGERLTLRRVLSGVVIVAGTIVLG 278 LRETSV+FA LIG FLGE LT+R+VL+ VVI GTI++G Sbjct: 236 LRETSVVFAALIGYYFLGESLTVRKVLACVVIATGTILIG 275 >A4WB79.1 A4WB79_ENT38 Putative uncharacterized protein Length = 275 Score = 242 bits (617), Expect = 5e-62, Method: Compositional matrix adjust. Identities = 145/281 (51%), Positives = 189/281 (67%), Gaps = 17/281 (6%) Query: 5 VIALVLAAALLHASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWFYIIL 64 ++ L L AALLHASWN LL+ + DRL S+ +M + + + + L P P ASW Y+ + Sbjct: 5 IVFLTLFAALLHASWNTLLRGATDRLWSMTIMCVAIAVTSAVIALLVPLPSTASWKYMFV 64 Query: 65 SGLLHTGYNLFLIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGILLVS 124 S LLH GYNL LIR+Y+ GD GQSYPIARG SPLLVA AA+FAGE++ L T+ GI LVS Sbjct: 65 SALLHVGYNLCLIRSYQSGDLGQSYPIARGCSPLLVACAAALFAGEKIELNTLGGITLVS 124 Query: 125 LGIVSLADLRAMRSREHLAGP--LAAFATGAFIAAYTITDGIGARLAGDAMSYAGWLFVL 182 GI+ L AM+ + LA P A ATGAFIAAY++ DGIG R +G+A+SY W+ L Sbjct: 125 CGILML----AMKGYK-LAMPDLKYALATGAFIAAYSVVDGIGVRFSGNALSYTAWMSTL 179 Query: 183 -----DSIALAVIYQRRHGRWPIALGRRETWIGLGGGVMSLLAYGIVIWAVTLAPMGMVS 237 ++ +A+ R RW L R GG++SLLAYGI+I+A+ APMG VS Sbjct: 180 WGGLMPALYIALRDSRSLLRWRPGLPRAAI-----GGLVSLLAYGIIIYAMQGAPMGTVS 234 Query: 238 ALRETSVLFALLIGALFLGERLTLRRVLSGVVIVAGTIVLG 278 ALRETSVLFA ++G LFLGE LTLR+ L+ +VI GT+++G Sbjct: 235 ALRETSVLFAAVLGYLFLGESLTLRKTLASIVIATGTLIIG 275 >E8Y160.1 E8Y160_RAHSY Putative uncharacterized protein Length = 275 Score = 240 bits (612), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 140/275 (50%), Positives = 188/275 (68%), Gaps = 5/275 (1%) Query: 5 VIALVLAAALLHASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWFYIIL 64 +I L L AALLHASWNALL+S DRL S+ +M + + + L+ P P+ AS Y +L Sbjct: 5 IIFLTLFAALLHASWNALLRSGTDRLWSMTIMCVTIAVTCGVIALFLPLPDFASAKYAVL 64 Query: 65 SGLLHTGYNLFLIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGILLVS 124 S LLH GYNL LIR+Y+ GD GQ+YPIARGSSPL+V GAA+FAGE++ T++GI L+S Sbjct: 65 SALLHVGYNLCLIRSYQSGDLGQTYPIARGSSPLMVTCGAALFAGEKIAFNTLVGIALIS 124 Query: 125 LGIVSLADLRAMRSRE-HLAGPLAAFATGAFIAAYTITDGIGARLAGDAMSYAGWLFVLD 183 GI+ L AMRSR+ + G ATGAFIAAY++ DGIG R++G++ SY W+ +L Sbjct: 125 GGILML----AMRSRKLAIPGLKYPLATGAFIAAYSVVDGIGVRVSGNSFSYTVWMSMLW 180 Query: 184 SIALAVIYQRRHGRWPIALGRRETWIGLGGGVMSLLAYGIVIWAVTLAPMGMVSALRETS 243 + + +Y + R GGV+SLLAYG++I+A+ APMG VSALRETS Sbjct: 181 GVLMPALYIALRDTKSLLRWRPGLLSAAAGGVVSLLAYGMIIYAMVAAPMGAVSALRETS 240 Query: 244 VLFALLIGALFLGERLTLRRVLSGVVIVAGTIVLG 278 VLFA ++G LFLGE LTLR++L+ VI GT+++G Sbjct: 241 VLFAAVLGYLFLGETLTLRKMLACAVIATGTLLIG 275 >D4E4F7.1 D4E4F7_SEROD Integral membrane protein Length = 275 Score = 238 bits (608), Expect = 6e-61, Method: Compositional matrix adjust. Identities = 147/281 (52%), Positives = 186/281 (66%), Gaps = 17/281 (6%) Query: 5 VIALVLAAALLHASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWFYIIL 64 +I L L AALLHASWN LL+ DRL S+ +M L + + + P P ASW Y +L Sbjct: 5 IILLTLFAALLHASWNTLLRGGTDRLWSMTIMCLAIAVSCALAMPFLPLPASASWRYALL 64 Query: 65 SGLLHTGYNLFLIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGILLVS 124 S LLH GYNL LIR+Y G+ GQ+YPIARGS+PLLV AA+ AGEQ+ L T+ GI LV Sbjct: 65 SALLHVGYNLCLIRSYHSGELGQTYPIARGSAPLLVTCAAALLAGEQIELNTLGGIALVC 124 Query: 125 LGIVSLADLRAMRSREHLAGPLA--AFATGAFIAAYTITDGIGARLAGDAMSYAGWLFVL 182 +GI+ L A R R+ L P A ATG FIAAY++ DGIG RL+G+A+SY W+ L Sbjct: 125 VGIL----LLAFRGRK-LTRPTVQYALATGVFIAAYSVVDGIGVRLSGNALSYTVWMSAL 179 Query: 183 DSIALAVIY-QRRHG----RWPIALGRRETWIGLGGGVMSLLAYGIVIWAVTLAPMGMVS 237 I + +Y R G RW +GR T GGV+SLLAYGI+I+A+ APMG VS Sbjct: 180 WGILMPALYIALRDGKSLLRWRAGVGRAAT-----GGVVSLLAYGIIIYAMAAAPMGAVS 234 Query: 238 ALRETSVLFALLIGALFLGERLTLRRVLSGVVIVAGTIVLG 278 ALRETSVLFA L+G LFLGE LTL ++L+ VIV+G +++G Sbjct: 235 ALRETSVLFAALLGYLFLGETLTLGKMLACTVIVSGIVIMG 275