BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0004.p (232 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8ITQ4.1 D8ITQ4_HERSS Response regulator for cobalt/zinc/cadmium... 455 e-126 Q470K3.1 Q470K3_CUPPJ Two component heavy metal response transcr... 329 2e-88 Q1LMJ6.1 Q1LMJ6_RALME DNA-binding response regulator in two-comp... 321 4e-86 B5SBZ2.1 B5SBZ2_RALSO Response regulator protein for cobalt zinc... 318 5e-85 B5S3Z4.1 B5S3Z4_RALSO Response regulator protein for cobalt zinc... 317 6e-85 A3RWM8.1 A3RWM8_RALSO CzcR 316 2e-84 Q8XSI5.1 Q8XSI5_RALSO Probable response regulator for cobalt zin... 315 3e-84 D8NGU3.1 D8NGU3_RALSO Response regulator in two-component regula... 315 4e-84 D8MZI6.1 D8MZI6_RALSO Response regulator in two-component regula... 315 4e-84 Q46U67.1 Q46U67_CUPPJ Heavy metal response regulator 313 9e-84 >D8ITQ4.1 D8ITQ4_HERSS Response regulator for cobalt/zinc/cadmium resistance transcription regulator protein Length = 235 Score = 455 bits (1170), Expect = e-126, Method: Compositional matrix adjust. Identities = 232/235 (98%), Positives = 232/235 (98%), Gaps = 3/235 (1%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW Sbjct: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS Sbjct: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM Sbjct: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFEVREG---REVREERP 232 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFEVREG REVREERP Sbjct: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFEVREGREVREVREERP 235 >Q470K3.1 Q470K3_CUPPJ Two component heavy metal response transcriptional regulator, winged helix family Length = 224 Score = 329 bits (844), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 165/222 (74%), Positives = 187/222 (84%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 M IL+VEDEPK+G+YLR+GLTES FVVD TG DGLH A +Y LIILDVMLPGM+GW Sbjct: 1 MKILVVEDEPKTGEYLRKGLTESSFVVDVAVTGGDGLHQATEHEYDLIILDVMLPGMSGW 60 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 D+LR+LR DTPVLFLTARDEVEDRV+GLELG DDYL KPFA+ ELLARVRTLLRRGP Sbjct: 61 DVLRQLRERKDTPVLFLTARDEVEDRVRGLELGGDDYLAKPFAFVELLARVRTLLRRGPV 120 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 RE D IE D+ +DV+R +VTRAGQRIDLT +EFALLH L RR GEVLSR IASQVWDM Sbjct: 121 READRIEIGDLEIDVIRHRVTRAGQRIDLTPREFALLHFLARRHGEVLSRTHIASQVWDM 180 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFEVR 222 NFDSDTNVVDVA+RRLRAK+D+ F KL+H+V G+GYV E+R Sbjct: 181 NFDSDTNVVDVAIRRLRAKMDDHFAPKLIHSVRGIGYVLEIR 222 >Q1LMJ6.1 Q1LMJ6_RALME DNA-binding response regulator in two-component regulatory system with AgrS Length = 224 Score = 321 bits (823), Expect = 4e-86, Method: Compositional matrix adjust. Identities = 158/224 (70%), Positives = 187/224 (83%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 M IL++EDEPK+G+YLR+GLTES FVVD TG DGLH+A DY L+ILDVMLPGMNGW Sbjct: 1 MKILVIEDEPKTGEYLRKGLTESSFVVDLASTGRDGLHHAIDGDYDLVILDVMLPGMNGW 60 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 ++L+ELR DTPVLFLTARDEVEDRVKGLELG DDYL KPFA+ ELLAR RTLLRRGP+ Sbjct: 61 EVLKELREHKDTPVLFLTARDEVEDRVKGLELGGDDYLAKPFAFVELLARARTLLRRGPT 120 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 RE + IE +D+ +D+LR +V+R G RIDL+ +EFALLH L RR GEVLSR QIAS VWDM Sbjct: 121 REAERIEIEDLEIDLLRHRVSRGGIRIDLSPREFALLHFLARRHGEVLSRTQIASHVWDM 180 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFEVREG 224 NFDSDTNVVDVA+RRLRAK+D+ + KL+H+V G+GYV E R+ Sbjct: 181 NFDSDTNVVDVAIRRLRAKMDDTYAPKLIHSVRGIGYVLENRQS 224 >B5SBZ2.1 B5SBZ2_RALSO Response regulator protein for cobalt zinc cadmium resistance Length = 224 Score = 318 bits (814), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 153/220 (69%), Positives = 189/220 (85%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 M +L+VEDEPK+GDYL +GLTESGFV D ++G DGL+ A DY LI+LDVMLPGM+GW Sbjct: 1 MRLLIVEDEPKAGDYLLKGLTESGFVADLARSGPDGLYQAMEHDYDLIVLDVMLPGMDGW 60 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 ++RELRR TPVLFLTARDE+ DR+KGLELGADDYLVKPFA+ EL+ARVRT+LRRGP Sbjct: 61 QVIRELRRRKATPVLFLTARDELSDRLKGLELGADDYLVKPFAFAELVARVRTILRRGPM 120 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 RE ++++ D+ +D ++R+VTRAGQRIDLTAKE+ALLH+L RR GEVLSR I+SQVWD+ Sbjct: 121 RESEILDIADLSIDTIKRRVTRAGQRIDLTAKEYALLHLLARRAGEVLSRSLISSQVWDV 180 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFE 220 NFDS+TNVVDVA+RRLRAK+D+ FE KL+HT+ GMGYV + Sbjct: 181 NFDSNTNVVDVAIRRLRAKVDDPFEHKLIHTLRGMGYVLD 220 >B5S3Z4.1 B5S3Z4_RALSO Response regulator protein for cobalt zinc cadmium resistance Length = 224 Score = 317 bits (813), Expect = 6e-85, Method: Compositional matrix adjust. Identities = 153/220 (69%), Positives = 189/220 (85%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 M +L+VEDEPK+GDYL +GLTESGFV D ++G DGL+ A DY LI+LDVMLPGM+GW Sbjct: 1 MRLLIVEDEPKAGDYLLKGLTESGFVADLARSGPDGLYQAMEHDYDLIVLDVMLPGMDGW 60 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 ++RELRR TPVLFLTARDE+ DR+KGLELGADDYLVKPFA+ EL+ARVRT+LRRGP Sbjct: 61 QVIRELRRRKPTPVLFLTARDELSDRLKGLELGADDYLVKPFAFAELVARVRTILRRGPM 120 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 RE ++++ D+ +D ++R+VTRAGQRIDLTAKE+ALLH+L RR GEVLSR I+SQVWD+ Sbjct: 121 RESEILDIADLSIDTIKRRVTRAGQRIDLTAKEYALLHLLARRAGEVLSRSLISSQVWDV 180 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFE 220 NFDS+TNVVDVA+RRLRAK+D+ FE KL+HT+ GMGYV + Sbjct: 181 NFDSNTNVVDVAIRRLRAKVDDPFEHKLIHTLRGMGYVLD 220 >A3RWM8.1 A3RWM8_RALSO CzcR Length = 248 Score = 316 bits (809), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 153/220 (69%), Positives = 189/220 (85%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 M +L+VEDEPK+GDYL +GLTESGFV D ++G DGL+ A DY LI+LDVMLPGM+GW Sbjct: 25 MRLLIVEDEPKAGDYLLKGLTESGFVADLARSGPDGLYQAMEHDYDLIVLDVMLPGMDGW 84 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 ++RELRR TPVLFLTARDE+ DR+KGLELGADDYLVKPFA+ EL+ARVRT+LRRGP Sbjct: 85 QVIRELRRRKATPVLFLTARDELSDRLKGLELGADDYLVKPFAFAELVARVRTILRRGPM 144 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 RE ++++ D+ +D ++R+VTRAGQRIDLTAKE+ALLH+L RR GEVLSR I+SQVWD+ Sbjct: 145 RESEILDIADLSIDTIKRRVTRAGQRIDLTAKEYALLHLLARRAGEVLSRSLISSQVWDV 204 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFE 220 NFDS+TNVVDVA+RRLRAK+D+ FE KL+HT+ GMGYV + Sbjct: 205 NFDSNTNVVDVAIRRLRAKVDDPFEHKLIHTLRGMGYVLD 244 >Q8XSI5.1 Q8XSI5_RALSO Probable response regulator for cobalt zinc cadmium resistance transcription regulator protein Length = 224 Score = 315 bits (807), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 152/220 (69%), Positives = 188/220 (85%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 M +L+VEDEPK+GDYL +GLTESGFV D ++G DGL+ A DY LI+LDVMLPGM+GW Sbjct: 1 MRLLIVEDEPKAGDYLLKGLTESGFVADLARSGPDGLYQAMEHDYDLIVLDVMLPGMDGW 60 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 ++RELRR TPVLFLTARDE+ DR+KGLELGADDYLVKPFA+ EL+ARV T+LRRGP Sbjct: 61 QVIRELRRRKTTPVLFLTARDELSDRLKGLELGADDYLVKPFAFAELVARVHTILRRGPM 120 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 RE +++E D+ +D ++R+VTRAG+RIDLTAKE+ALLH+L RR GEVLSR I+SQVWD+ Sbjct: 121 RESEVLEIADLTIDTIKRRVTRAGRRIDLTAKEYALLHLLARRTGEVLSRSLISSQVWDV 180 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFE 220 NFDS+TNVVDVA+RRLRAK+D+ FE KL+HT+ GMGYV + Sbjct: 181 NFDSNTNVVDVAIRRLRAKVDDPFEHKLIHTLRGMGYVLD 220 >D8NGU3.1 D8NGU3_RALSO Response regulator in two-component regulatory system, regulation of heavy metal resistance operon czcCBA Length = 224 Score = 315 bits (807), Expect = 4e-84, Method: Compositional matrix adjust. Identities = 152/220 (69%), Positives = 188/220 (85%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 M +L+VEDEPK+GDYL +GLTESGFV D ++G DGL+ A DY LI+LDVMLPGM+GW Sbjct: 1 MRLLIVEDEPKAGDYLLKGLTESGFVADLARSGPDGLYQAMEHDYDLIVLDVMLPGMDGW 60 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 ++RELRR TPVLFLTARDE+ DR+KGLELGADDYLVKPFA+ EL+ARV T+LRRGP Sbjct: 61 QVIRELRRRKTTPVLFLTARDELSDRLKGLELGADDYLVKPFAFAELVARVHTILRRGPM 120 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 RE +++E D+ +D ++R+VTRAG+RIDLTAKE+ALLH+L RR GEVLSR I+SQVWD+ Sbjct: 121 RESEVLEIADLTIDTIKRRVTRAGRRIDLTAKEYALLHLLARRTGEVLSRSLISSQVWDV 180 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFE 220 NFDS+TNVVDVA+RRLRAK+D+ FE KL+HT+ GMGYV + Sbjct: 181 NFDSNTNVVDVAIRRLRAKVDDPFEPKLIHTLRGMGYVLD 220 >D8MZI6.1 D8MZI6_RALSO Response regulator in two-component regulatory system, regulation of heavy metal resistance operon czcCBA Length = 224 Score = 315 bits (807), Expect = 4e-84, Method: Compositional matrix adjust. Identities = 152/221 (68%), Positives = 188/221 (85%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 M +L+VEDEPK+GDYL +GLTESGFV D ++G DGL+ A DY LI+LDVMLPGM+GW Sbjct: 1 MRLLIVEDEPKAGDYLLKGLTESGFVADLARSGPDGLYQAMEHDYDLIVLDVMLPGMDGW 60 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 ++RELRR TPVLFLTARDE+ DR+KGLELGADDYLVKPFA+ EL+ARV T+LRRGP Sbjct: 61 QVIRELRRHKTTPVLFLTARDELSDRLKGLELGADDYLVKPFAFAELVARVHTILRRGPM 120 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 RE +++E D+ +D ++R+VTRAG+RIDLTAKE+ALLH+L RR GEVLSR I+SQVWD+ Sbjct: 121 RESEVLEIADLTIDTIKRRVTRAGRRIDLTAKEYALLHLLARRTGEVLSRSLISSQVWDV 180 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFEV 221 NFDS+TNVVDVA+RRLRAK+D+ FE KL+HT+ GMGYV + Sbjct: 181 NFDSNTNVVDVAIRRLRAKVDDPFEHKLIHTLRGMGYVLDT 221 >Q46U67.1 Q46U67_CUPPJ Heavy metal response regulator Length = 229 Score = 313 bits (803), Expect = 9e-84, Method: Compositional matrix adjust. Identities = 153/220 (69%), Positives = 189/220 (85%) Query: 1 MHILLVEDEPKSGDYLRRGLTESGFVVDWVQTGVDGLHNARTLDYKLIILDVMLPGMNGW 60 M IL+VEDEPK+GDYL +GLTESGFVVD + GVDGL +AR Y LI+LDVMLPGM+GW Sbjct: 1 MRILIVEDEPKAGDYLLKGLTESGFVVDLARDGVDGLAHAREQPYDLIVLDVMLPGMDGW 60 Query: 61 DILRELRRTHDTPVLFLTARDEVEDRVKGLELGADDYLVKPFAYTELLARVRTLLRRGPS 120 +LRELRR DTPVLFLTARDE++DR+KGLELGADDY+VKPFA+ EL+ R+RT+LRRGP Sbjct: 61 SVLRELRRERDTPVLFLTARDELQDRLKGLELGADDYMVKPFAFAELVMRIRTILRRGPL 120 Query: 121 REVDLIEYDDVVLDVLRRKVTRAGQRIDLTAKEFALLHMLIRRPGEVLSRPQIASQVWDM 180 RE + IE D+ +D +RR+V+R+GQ+IDLT+KEFALL++L RR GEVLSR IASQVWD+ Sbjct: 121 RESEFIEVADLQIDAIRRRVSRSGQKIDLTSKEFALLYLLARRRGEVLSRSLIASQVWDV 180 Query: 181 NFDSDTNVVDVAVRRLRAKLDEGFEKKLLHTVWGMGYVFE 220 NFDS+TNVVDV++RRLRAK+D+ F+ KL+HT GMGYV + Sbjct: 181 NFDSNTNVVDVSIRRLRAKVDDPFDHKLIHTRRGMGYVLD 220