BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0294.p (277 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IUL4.1 D8IUL4_HERSS Polypeptide chain release factors methylas... 547 e-154 A6SUF4.1 A6SUF4_JANMA Methylase of polypeptide chain release fac... 357 1e-96 A4G1N0.1 A4G1N0_HERAR Protein methyltransferase HemK (Protein-gl... 336 3e-90 F1VX62.1 F1VX62_9BURK Methylase of polypeptide chain release factor 330 1e-88 C3X9Z9.1 C3X9Z9_OXAFO Methyltransferase HemK MTase hemK 323 2e-86 C3X2B7.1 C3X2B7_OXAFO Methyltransferase HemK MTase hemK 316 2e-84 D5NGZ2.1 D5NGZ2_9BURK Protein-(Glutamine-N5) methyltransferase, ... 286 3e-75 E1TAP1.1 E1TAP1_BURSG Protein-(Glutamine-N5) methyltransferase, ... 284 1e-74 Q1LIF1.1 Q1LIF1_RALME N5-glutamine methyltransferase, modifies r... 284 1e-74 C1D8T7.1 C1D8T7_LARHH HemK1 281 8e-74 >D8IUL4.1 D8IUL4_HERSS Polypeptide chain release factors methylase protein EC=2.1.1.- Length = 277 Score = 547 bits (1409), Expect = e-154, Method: Compositional matrix adjust. Identities = 277/277 (100%), Positives = 277/277 (100%) Query: 1 MPILPSYAGCTLATVLKTAPLDPLENRILLCHALRLTRVQLITQSERQLSAAEAETLAAL 60 MPILPSYAGCTLATVLKTAPLDPLENRILLCHALRLTRVQLITQSERQLSAAEAETLAAL Sbjct: 1 MPILPSYAGCTLATVLKTAPLDPLENRILLCHALRLTRVQLITQSERQLSAAEAETLAAL 60 Query: 61 LARRLRGEPIAYIVGQREFYGLDLRVSPDVLIPRPDTELLVELALERLPQGGSALDMGTG 120 LARRLRGEPIAYIVGQREFYGLDLRVSPDVLIPRPDTELLVELALERLPQGGSALDMGTG Sbjct: 61 LARRLRGEPIAYIVGQREFYGLDLRVSPDVLIPRPDTELLVELALERLPQGGSALDMGTG 120 Query: 121 SGAIAVAIAHTRPDAQVTALDASPAALAIARENASTHQVRVRLLESDWYGALDADQAFDL 180 SGAIAVAIAHTRPDAQVTALDASPAALAIARENASTHQVRVRLLESDWYGALDADQAFDL Sbjct: 121 SGAIAVAIAHTRPDAQVTALDASPAALAIARENASTHQVRVRLLESDWYGALDADQAFDL 180 Query: 181 IVSNPPYIVAGDIHLSQGDLRFEPVDALTDHADGLSDLRTIIEGAPAHLKAGGWLLMEHG 240 IVSNPPYIVAGDIHLSQGDLRFEPVDALTDHADGLSDLRTIIEGAPAHLKAGGWLLMEHG Sbjct: 181 IVSNPPYIVAGDIHLSQGDLRFEPVDALTDHADGLSDLRTIIEGAPAHLKAGGWLLMEHG 240 Query: 241 YDQAAAVRALLTGGGWREVQSWRDLAGIERVSGARLG 277 YDQAAAVRALLTGGGWREVQSWRDLAGIERVSGARLG Sbjct: 241 YDQAAAVRALLTGGGWREVQSWRDLAGIERVSGARLG 277 >A6SUF4.1 A6SUF4_JANMA Methylase of polypeptide chain release factors Length = 280 Score = 357 bits (915), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 185/268 (69%), Positives = 210/268 (78%), Gaps = 1/268 (0%) Query: 8 AGCTLATVLKTAPLDPLENRILLCHALRLTRVQLITQSERQLSAAEAETLAALLARRLRG 67 AG T+A V++ AP+ LE RILL + RL+RVQLITQ+ER L+A EA+ L+ L ARRL G Sbjct: 10 AGTTVAAVMQRAPVAQLEARILLGYVTRLSRVQLITQAERALTAEEAQQLSQLFARRLAG 69 Query: 68 EPIAYIVGQREFYGLDLRVSPDVLIPRPDTELLVELALERLPQGGSALDMGTGSGAIAVA 127 EPIAY+ G+REF+GL VSP VLIPRPDTELLVELAL LP G LDMGTGSGAIAVA Sbjct: 70 EPIAYLTGEREFFGLSFDVSPAVLIPRPDTELLVELALHYLPPQGRVLDMGTGSGAIAVA 129 Query: 128 IAHTRPDAQVTALDASPAALAIARENASTHQVRVRLLESDWYGALDADQAFDLIVSNPPY 187 IAH RPDA VTALD S ALAIA NA +QV+V L SDW+ A+ +Q FDLIVSNPPY Sbjct: 130 IAHARPDAFVTALDVSAEALAIAEGNARKNQVQVNFLRSDWFSAVK-EQRFDLIVSNPPY 188 Query: 188 IVAGDIHLSQGDLRFEPVDALTDHADGLSDLRTIIEGAPAHLKAGGWLLMEHGYDQAAAV 247 IVAGD HLS+GDLRFEPVDALTDHA+GLSDL+TI A +L WLLMEHGYDQAAAV Sbjct: 189 IVAGDPHLSEGDLRFEPVDALTDHANGLSDLQTITRDAARYLAPAAWLLMEHGYDQAAAV 248 Query: 248 RALLTGGGWREVQSWRDLAGIERVSGAR 275 R +L G+ EVQSWRDLAGIERVSG + Sbjct: 249 RDVLATHGFTEVQSWRDLAGIERVSGGK 276 >A4G1N0.1 A4G1N0_HERAR Protein methyltransferase HemK (Protein-glutamine N-methyltransferase hemK) (Protein-(Glutamine-N5) MTase hemK) EC=2.1.1.- Length = 276 Score = 336 bits (861), Expect = 3e-90, Method: Compositional matrix adjust. Identities = 187/268 (69%), Positives = 215/268 (80%), Gaps = 1/268 (0%) Query: 8 AGCTLATVLKTAPLDPLENRILLCHALRLTRVQLITQSERQLSAAEAETLAALLARRLRG 67 AG T+A +L+ AP++ LE R+L+ H +L+RVQLIT +ER L+AAEA+ LA L ARR+ G Sbjct: 6 AGDTIAAILRRAPVEQLEARMLIGHVTQLSRVQLITNAERVLNAAEAQQLATLFARRMAG 65 Query: 68 EPIAYIVGQREFYGLDLRVSPDVLIPRPDTELLVELALERLPQGGSALDMGTGSGAIAVA 127 EP+AY++G+REFYGL +VSP VLIPRPDTELLVELAL+RLPQ G LDMGTGSGAIA+A Sbjct: 66 EPMAYLLGEREFYGLSFQVSPAVLIPRPDTELLVELALQRLPQQGRVLDMGTGSGAIAIA 125 Query: 128 IAHTRPDAQVTALDASPAALAIARENASTHQVRVRLLESDWYGALDADQAFDLIVSNPPY 187 IAH RPDA VTALD S AALA+A NA H+ RV L SDW+ ALD Q FDLIVSNPPY Sbjct: 126 IAHARPDAVVTALDVSEAALAVASANAHRHKARVECLRSDWFAALDGRQ-FDLIVSNPPY 184 Query: 188 IVAGDIHLSQGDLRFEPVDALTDHADGLSDLRTIIEGAPAHLKAGGWLLMEHGYDQAAAV 247 IVAGD HLS+GDLRFEP+DAL+DHADGLS LR I E A HL GWLLMEHGYDQAAAV Sbjct: 185 IVAGDRHLSEGDLRFEPIDALSDHADGLSALRIISEHAADHLSDDGWLLMEHGYDQAAAV 244 Query: 248 RALLTGGGWREVQSWRDLAGIERVSGAR 275 R LL G+ EVQSWRDLA IERVSG + Sbjct: 245 RGLLAENGFGEVQSWRDLAQIERVSGGK 272 >F1VX62.1 F1VX62_9BURK Methylase of polypeptide chain release factor Length = 278 Score = 330 bits (846), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 179/276 (64%), Positives = 214/276 (77%), Gaps = 5/276 (1%) Query: 1 MPILPSYAGCTLATVLKT-APLDPLENRILLCHALRLTRVQLITQSERQLSAAEAETLAA 59 MP++ AG T+ VL+ APL E RILL HAL LTR++LIT +E+ L+ A+A+ ++A Sbjct: 1 MPLI--VAGETIEAVLRQPAPLLA-ERRILLGHALGLTRIELITGNEQMLTPAQAQRVSA 57 Query: 60 LLARRLRGEPIAYIVGQREFYGLDLRVSPDVLIPRPDTELLVELALERLPQGGSALDMGT 119 L RR+ GEPIAY+VG REFYGL V+P VLIPRP+TELLVELA++RLP+ G LDMGT Sbjct: 58 LFERRIAGEPIAYLVGTREFYGLRFEVTPAVLIPRPETELLVELAIDRLPRQGRVLDMGT 117 Query: 120 GSGAIAVAIAHTRPDAQVTALDASPAALAIARENASTHQVRVRLLESDWYGALDADQAFD 179 GSGAIAVA+A++R DA V+A+D S AALA+AR NA+ H V+V L SDWY AL+ Q FD Sbjct: 118 GSGAIAVALANSRRDAAVSAIDFSDAALAVARRNAAHHAVQVHLQRSDWYAALEG-QCFD 176 Query: 180 LIVSNPPYIVAGDIHLSQGDLRFEPVDALTDHADGLSDLRTIIEGAPAHLKAGGWLLMEH 239 +IV+NPPYIV GD HLS+GDLRFEPVDALTDHADGLS LR I+ GA A L GWLLMEH Sbjct: 177 MIVANPPYIVEGDHHLSEGDLRFEPVDALTDHADGLSALRQIVSGATAALAPAGWLLMEH 236 Query: 240 GYDQAAAVRALLTGGGWREVQSWRDLAGIERVSGAR 275 GYDQAAAV ALL + +VQSW DLAGI RVSG R Sbjct: 237 GYDQAAAVCALLDAAQFTDVQSWPDLAGIARVSGGR 272 >C3X9Z9.1 C3X9Z9_OXAFO Methyltransferase HemK MTase hemK Length = 279 Score = 323 bits (828), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 164/272 (60%), Positives = 202/272 (74%), Gaps = 4/272 (1%) Query: 8 AGCTLATVLKTAPLDPLENRILLCHALRLTRVQLITQSERQLSAAEAETLAALLARRLRG 67 AG T+ ++ T PLDPLE RILL +A+ +RV+LIT S+ L+ +A+ L+ +++RR+ G Sbjct: 6 AGMTIRSLFSTVPLDPLELRILLEYAIGFSRVKLITHSDHPLTTEQAKALSDVVSRRVCG 65 Query: 68 EPIAYIVGQREFYGLDLRVSPDVLIPRPDTELLVELALERLPQGGSALDMGTGSGAIAVA 127 EP+AYI G+REF+GL V PDVLIPRP+TELLVELALERLP GG +DMGTGSGAIA+A Sbjct: 66 EPVAYITGKREFFGLSFAVCPDVLIPRPETELLVELALERLPHGGKIVDMGTGSGAIAIA 125 Query: 128 IAHTRPDAQVTALDASPAALAIARENA---STHQVRVRLLESDWYGAL-DADQAFDLIVS 183 IA RPDA V A D S AL +A NA + V +W+ AL + ++ FDLIVS Sbjct: 126 IASERPDAHVFATDVSEKALNMATHNALALLKGKQTVHFSAGNWFYALKNVNETFDLIVS 185 Query: 184 NPPYIVAGDIHLSQGDLRFEPVDALTDHADGLSDLRTIIEGAPAHLKAGGWLLMEHGYDQ 243 NPPYI + D HL +GDLRFEPV ALTDHADGLS L+ ++ GA A+LK GGWLLMEHGYDQ Sbjct: 186 NPPYIDSKDDHLQKGDLRFEPVGALTDHADGLSALKILVSGAQAYLKRGGWLLMEHGYDQ 245 Query: 244 AAAVRALLTGGGWREVQSWRDLAGIERVSGAR 275 A AVRALL G+ EVQSW+DLAGI RVSG + Sbjct: 246 AVAVRALLARAGFEEVQSWKDLAGIGRVSGGK 277 >C3X2B7.1 C3X2B7_OXAFO Methyltransferase HemK MTase hemK Length = 287 Score = 316 bits (810), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 165/272 (60%), Positives = 203/272 (74%), Gaps = 3/272 (1%) Query: 8 AGCTLATVLKTAPLDPLENRILLCHALRLTRVQLITQSERQLSAAEAETLAALLARRLRG 67 AG T+ ++ PL+P E RILL HAL +RV+LIT S+ L+ AEA ++ +LARRLRG Sbjct: 14 AGMTIRSLFSLVPLEPPELRILLEHALGFSRVKLITHSDHVLTDAEANAVSDVLARRLRG 73 Query: 68 EPIAYIVGQREFYGLDLRVSPDVLIPRPDTELLVELALERLPQGGSALDMGTGSGAIAVA 127 EP+AYI G REFYGL V+PDVLIPRP+TELLV+LAL RLP+GG +D+GTGSGAIAVA Sbjct: 74 EPVAYITGIREFYGLPFAVTPDVLIPRPETELLVDLALARLPEGGRVVDLGTGSGAIAVA 133 Query: 128 IAHTRPDAQVTALDASPAALAIARENAST---HQVRVRLLESDWYGALDADQAFDLIVSN 184 IA RPDAQV A D S AL IAR+NA++ + VR + +WY AL+ FDLIVSN Sbjct: 134 IAAMRPDAQVWATDISGKALDIARKNAASCLKNGQSVRFRQGNWYEALEPGSRFDLIVSN 193 Query: 185 PPYIVAGDIHLSQGDLRFEPVDALTDHADGLSDLRTIIEGAPAHLKAGGWLLMEHGYDQA 244 PPYI + D HL +GDLRFEP+ ALTD+ DGLS + +I+ APA+LK GG LLMEHGY+Q+ Sbjct: 194 PPYIHSADEHLRKGDLRFEPLSALTDYTDGLSAMDILIDQAPAYLKKGGELLMEHGYNQS 253 Query: 245 AAVRALLTGGGWREVQSWRDLAGIERVSGARL 276 AVR L + +VQSW+DLAGIERVSG RL Sbjct: 254 GAVRKKLVDKKYLQVQSWKDLAGIERVSGGRL 285 >D5NGZ2.1 D5NGZ2_9BURK Protein-(Glutamine-N5) methyltransferase, release factor-specific Length = 281 Score = 286 bits (731), Expect = 3e-75, Method: Compositional matrix adjust. Identities = 163/276 (59%), Positives = 191/276 (69%), Gaps = 8/276 (2%) Query: 10 CTLATVLKTAPLDPLENRILLCHALRLTRVQLITQSERQLSAAEAETLAALLARRLRGEP 69 T A +++T+PL PLE RILL H L QLIT+S+ L A E AL ARR GEP Sbjct: 5 ATPAALMRTSPLPPLEARILLTHVLGWRPTQLITRSDEPLQAEVVERYRALEARRAAGEP 64 Query: 70 IAYIVGQREFYGLDLRVSPDVLIPRPDTELLVELALERLPQGGS--ALDMGTGSGAIAVA 127 +A +VG REF+GL+ V+P VLIPRP+TELLVE AL L LD+GTG+GAIAVA Sbjct: 65 VAQLVGAREFFGLNFEVTPHVLIPRPETELLVETALAALENLARPRVLDLGTGTGAIAVA 124 Query: 128 IAHTRPDAQVTALDASPAALAIARENASTHQVRVR------LLESDWYGALDADQAFDLI 181 IA RPDAQV ALD S ALA+A NA+ R L +SDWYG+LDA F +I Sbjct: 125 IASMRPDAQVWALDRSAEALAVATRNAARLLDAKRPGGAVVLTQSDWYGSLDAALRFHVI 184 Query: 182 VSNPPYIVAGDIHLSQGDLRFEPVDALTDHADGLSDLRTIIEGAPAHLKAGGWLLMEHGY 241 VSNPPYI +GD HL+QGDLRFEP ALTD ADGLS +R II GAP L AGG + +EHGY Sbjct: 185 VSNPPYIASGDPHLAQGDLRFEPRGALTDEADGLSAIRAIIAGAPTRLAAGGVVWIEHGY 244 Query: 242 DQAAAVRALLTGGGWREVQSWRDLAGIERVSGARLG 277 DQA AVR LLT G+ +V+S RDLAGIER+SG RLG Sbjct: 245 DQAEAVRELLTAQGFMQVRSERDLAGIERISGGRLG 280 >E1TAP1.1 E1TAP1_BURSG Protein-(Glutamine-N5) methyltransferase, release factor-specific Length = 289 Score = 284 bits (726), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 158/275 (57%), Positives = 194/275 (70%), Gaps = 8/275 (2%) Query: 10 CTLATVLKTAPLDPLENRILLCHALRLTRVQLITQSERQLSAAEAETLAALLARRLRGEP 69 T A +L+ +PL PLE RILL H L + QLIT+++ L +A E AL ARR+ GEP Sbjct: 13 ATPAALLRASPLPPLEARILLTHVLGWRQTQLITRADEALESACVERYLALQARRVAGEP 72 Query: 70 IAYIVGQREFYGLDLRVSPDVLIPRPDTELLVELALERLPQGGS--ALDMGTGSGAIAVA 127 +A +VG REF+GL+ V+P VLIPRP+TELLVE AL + LD+GTG+GAIAVA Sbjct: 73 VAQLVGVREFFGLEFEVTPHVLIPRPETELLVETALAAMENLARPRVLDLGTGTGAIAVA 132 Query: 128 IAHTRPDAQVTALDASPAALAIARENAST--HQVR----VRLLESDWYGALDADQAFDLI 181 IA RPDAQV+ALD S AL +A NA+ R V ++SDWYG+L++ FD+I Sbjct: 133 IAAMRPDAQVSALDRSTEALKVAERNAARLLDAKRPGGAVTFMQSDWYGSLESTLRFDVI 192 Query: 182 VSNPPYIVAGDIHLSQGDLRFEPVDALTDHADGLSDLRTIIEGAPAHLKAGGWLLMEHGY 241 VSNPPYI +GD HL+QGDLR+EP ALTD ADGLS +R I+ GAPA L G L MEHGY Sbjct: 193 VSNPPYIASGDPHLTQGDLRYEPRGALTDEADGLSAIRKIVAGAPARLAPQGVLWMEHGY 252 Query: 242 DQAAAVRALLTGGGWREVQSWRDLAGIERVSGARL 276 DQA AVRALLT G+ +V+S RDLAGIER+SG RL Sbjct: 253 DQAQAVRALLTAQGFADVRSERDLAGIERISGGRL 287 >Q1LIF1.1 Q1LIF1_RALME N5-glutamine methyltransferase, modifies release factors RF-1 and RF-2 EC=2.1.1.- Length = 310 Score = 284 bits (726), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 153/266 (57%), Positives = 181/266 (68%), Gaps = 3/266 (1%) Query: 14 TVLKTAPLDPLENRILLCHALRLTRVQLITQSERQLSAAEAETLAALLARRLRGEPIAYI 73 T+ A L LE R+LL H TR QLIT+ L A + + A LLARRL GEP+AY+ Sbjct: 43 TLAAIAGLPVLEARMLLSHVTGFTRTQLITRDNDHLDAPKRDAFATLLARRLTGEPMAYL 102 Query: 74 VGQREFYGLDLRVSPDVLIPRPDTELLVELALERLP--QGGSALDMGTGSGAIAVAIAHT 131 +G+REF+G RV+PDVLIPRPDTE+ E +L R+ + LDMGTGSG +AV IA Sbjct: 103 IGEREFFGRTFRVTPDVLIPRPDTEVAAEASLARIADVKAPRVLDMGTGSGILAVTIARE 162 Query: 132 RPDAQVTALDASPAALAIARENASTHQV-RVRLLESDWYGALDADQAFDLIVSNPPYIVA 190 RPDA+V A D S AL +A +NA Q +R L SDWY L F+LIVSNPPYI Sbjct: 163 RPDAEVWATDISRGALMVAEDNARALQAENIRFLVSDWYEDLPVGLCFNLIVSNPPYIAE 222 Query: 191 GDIHLSQGDLRFEPVDALTDHADGLSDLRTIIEGAPAHLKAGGWLLMEHGYDQAAAVRAL 250 GD HL +GDLRFEP+DALTDH DGLSDL TI+ GA A L GGWLLMEHGYDQ AA+RA Sbjct: 223 GDPHLVEGDLRFEPIDALTDHEDGLSDLATIVAGATARLLPGGWLLMEHGYDQGAAMRAQ 282 Query: 251 LTGGGWREVQSWRDLAGIERVSGARL 276 L G+ EV + RDLAG+ER SG RL Sbjct: 283 LAEAGFVEVFTTRDLAGLERCSGGRL 308 >C1D8T7.1 C1D8T7_LARHH HemK1 Length = 276 Score = 281 bits (719), Expect = 8e-74, Method: Compositional matrix adjust. Identities = 147/262 (56%), Positives = 180/262 (68%) Query: 11 TLATVLKTAPLDPLENRILLCHALRLTRVQLITQSERQLSAAEAETLAALLARRLRGEPI 70 T+ +L LD L+ +LL A L+R + IT E+++ A+ AL ARRL GEP+ Sbjct: 5 TIGGLLAGCGLDRLDAHLLLEQASGLSRTRQITWPEQEVPEETAQRFLALAARRLAGEPV 64 Query: 71 AYIVGQREFYGLDLRVSPDVLIPRPDTELLVELALERLPQGGSALDMGTGSGAIAVAIAH 130 AY++G REF+G D RV+PD LIPRP+TE LVE AL LP G LD+GTGSGAIAV +A Sbjct: 65 AYLLGVREFFGRDFRVTPDTLIPRPETEHLVEFALTHLPPAGRMLDLGTGSGAIAVTVAC 124 Query: 131 TRPDAQVTALDASPAALAIARENASTHQVRVRLLESDWYGALDADQAFDLIVSNPPYIVA 190 RPDA+VTALD S AALA+AR N Q +VR LESDW+ AL A++ F+LIVSNPPYI A Sbjct: 125 ERPDARVTALDVSAAALAVARSNGQHLQAQVRWLESDWFSALPAEERFELIVSNPPYIAA 184 Query: 191 GDIHLSQGDLRFEPVDALTDHADGLSDLRTIIEGAPAHLKAGGWLLMEHGYDQAAAVRAL 250 GD HL QGDLRFEP ALTD ADGL L+ + A + GGWL +EHGYDQ A RAL Sbjct: 185 GDPHLEQGDLRFEPASALTDFADGLEALQVLATQACHFVTPGGWLAVEHGYDQGKACRAL 244 Query: 251 LTGGGWREVQSWRDLAGIERVS 272 G GW V + DLAG++RV+ Sbjct: 245 FAGAGWLSVSTLPDLAGLDRVT 266