BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0136.p (512 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8ITH2.1 D8ITH2_HERSS 3-hydroxyacyl-CoA dehydrogenase protein EC... 1050 0.0 Q47J50.1 Q47J50_DECAR 3-hydroxyacyl-CoA dehydrogenase EC=1.1.1.35 564 e-158 B5WSW7.1 B5WSW7_9BURK 3-hydroxybutyryl-CoA dehydrogenase EC=1.1.... 545 e-153 C7RTA6.1 C7RTA6_ACCPU 3-hydroxybutyryl-CoA dehydrogenase EC=1.1.... 544 e-152 Q397D0.1 Q397D0_BURS3 3-hydroxyacyl-CoA dehydrogenase EC=1.1.1.35 542 e-152 Q1BNS5.1 Q1BNS5_BURCA 3-hydroxyacyl-CoA dehydrogenase EC=1.1.1.35 540 e-151 A0B0T8.1 A0B0T8_BURCH 3-hydroxyacyl-CoA dehydrogenase EC=1.1.1.35 540 e-151 B1K3L1.1 B1K3L1_BURCC 3-hydroxybutyryl-CoA dehydrogenase EC=1.1.... 540 e-151 A4JP17.1 A4JP17_BURVG 3-hydroxyacyl-CoA dehydrogenase EC=1.1.1.35 539 e-151 A2VYH9.1 A2VYH9_9BURK 3-hydroxybutyryl-CoA dehydrogenase 539 e-151 >D8ITH2.1 D8ITH2_HERSS 3-hydroxyacyl-CoA dehydrogenase protein EC=1.1.1.35 Length = 512 Score = 1050 bits (2715), Expect = 0.0, Method: Compositional matrix adjust. Identities = 509/512 (99%), Positives = 510/512 (99%) Query: 1 MNNRKHPHALSRSALVAVIGSGTMGAGIAQVAAVAGHPVLLYDSREGAAGKAIGAICTNL 60 MNNRK+PHALSRSALVAVIGSGTMGAGIAQVAAVAGHPVLLYDSREGAAGKAIGAICTNL Sbjct: 1 MNNRKYPHALSRSALVAVIGSGTMGAGIAQVAAVAGHPVLLYDSREGAAGKAIGAICTNL 60 Query: 61 DKLVSKDKLTPALAQAASQRISVAHSLEELHQADLVIEAIVEQLAAKHELFGKLEAIVST 120 DKLVSKDKLTPALAQAASQRISVA SLEELHQADLVIEAIVEQLAAKHELFGKLEAIVST Sbjct: 61 DKLVSKDKLTPALAQAASQRISVAQSLEELHQADLVIEAIVEQLAAKHELFGKLEAIVST 120 Query: 121 RCILATNTSSLSITQIAAGLQHPERVVGMHFFNPVPMMALVEIISGLASDAALAQCLHDT 180 RCILATNTSSLSITQIAAGLQHPERVVGMHFFNPVPMMALVEIISGLASDAALAQCLHDT Sbjct: 121 RCILATNTSSLSITQIAAGLQHPERVVGMHFFNPVPMMALVEIISGLASDAALAQCLHDT 180 Query: 181 ALAWGKTPVMARSTPGFIVNRLARPYYAEGLRMLHEGGAQPATIDAVMREAGGFRMGPFE 240 ALAWGKTPVMARSTPGFIVNRLARPYYAEGLRMLHEGGAQPATIDAVMREAGGFRMGPFE Sbjct: 181 ALAWGKTPVMARSTPGFIVNRLARPYYAEGLRMLHEGGAQPATIDAVMREAGGFRMGPFE 240 Query: 241 LMDLIGHDVNFAVTQSVFHAYFNDPRFTPSLIQQELVHAGYLGRKSGRGFYRYGEAAGAP 300 LMDLIGHDVNFAVTQSVFHAYFNDPRFTPSLIQQELVHAGYLGRKSGRGFYRYGEAAGAP Sbjct: 241 LMDLIGHDVNFAVTQSVFHAYFNDPRFTPSLIQQELVHAGYLGRKSGRGFYRYGEAAGAP 300 Query: 301 RPETERDYPKPTATPQLYGDHPLVEMIHTRYPGQVQRHPARPDQLLMKVNAACLCITDGR 360 RPETERDYPKPTATPQLYGDHPLVEMIHTRYPGQVQRHPARPDQLLMKVNAACLCITDGR Sbjct: 301 RPETERDYPKPTATPQLYGDHPLVEMIHTRYPGQVQRHPARPDQLLMKVNAACLCITDGR 360 Query: 361 SATLRAWEHQEPDLVLVDLALDYADATRLALAKADQCRPQRYAEVAGVLQACGLDLSPMQ 420 SATLRAWEHQEPDLVLVDLALDYADATRLALAKADQCRPQRYAEVAGVLQACGLDLSPMQ Sbjct: 361 SATLRAWEHQEPDLVLVDLALDYADATRLALAKADQCRPQRYAEVAGVLQACGLDLSPMQ 420 Query: 421 DVPGMMVMRTVCMLVNEAADAVNQGVCNAADADMAMRKGVNYPRGPLAWANEIGIDTVTQ 480 DVPGMMVMRTVCMLVNEAADAVNQGVCNAADADMAMRKGVNYPRGPLAWANEIGIDTV Q Sbjct: 421 DVPGMMVMRTVCMLVNEAADAVNQGVCNAADADMAMRKGVNYPRGPLAWANEIGIDTVNQ 480 Query: 481 VLHHLCATYGEDRYRISPLLQRLYASGRKFHE 512 VLHHLCATYGEDRYRISPLLQRLYASGRKFHE Sbjct: 481 VLHHLCATYGEDRYRISPLLQRLYASGRKFHE 512 >Q47J50.1 Q47J50_DECAR 3-hydroxyacyl-CoA dehydrogenase EC=1.1.1.35 Length = 519 Score = 564 bits (1454), Expect = e-158, Method: Compositional matrix adjust. Identities = 298/513 (58%), Positives = 361/513 (70%), Gaps = 3/513 (0%) Query: 2 NNRKHPHALSRSALVAVIGSGTMGAGIAQVAAVAGHPVLLYDSREGAAGKAIGAICTNLD 61 + R L + A++AV+G+G MGAGIAQVAA AGHPV L D+R GAA KA+ I Sbjct: 8 SERVTKQPLPQQAVIAVVGTGAMGAGIAQVAAAAGHPVKLLDNRPGAADKAVAGIRAQFA 67 Query: 62 KLVSKDKLTPALAQAASQRISVAHSLEELHQADLVIEAIVEQLAAKHELFGKLEAIVSTR 121 KL K KLT AQAA +R+S L +L A LV+EAIVE L AK +L+ LEAIV Sbjct: 68 KLAEKGKLTTEAAQAAGERLSAVEQLADLADAALVVEAIVENLDAKQKLYADLEAIVGAD 127 Query: 122 CILATNTSSLSITQIAAGLQHPERVVGMHFFNPVPMMALVEIISGLASDAALAQCLHDTA 181 CI TNTSS+S+T I A L+HPER+ G+HFFNP P+MALVEI+SGLA+D A+A L TA Sbjct: 128 CIFGTNTSSISVTAIGAALKHPERLAGLHFFNPAPLMALVEIVSGLATDKAVADTLFSTA 187 Query: 182 LAWGKTPVMARSTPGFIVNRLARPYYAEGLRMLHEGGAQPATIDAVMREAGGFRMGPFEL 241 AWGKT V A+STPGFIVNR+ARPYYAE LR+ EG A ATIDA REAGGFRMGPFEL Sbjct: 188 NAWGKTAVHAKSTPGFIVNRVARPYYAEALRVAQEGAADYATIDACCREAGGFRMGPFEL 247 Query: 242 MDLIGHDVNFAVTQSVFHAYFNDPRFTPSLIQQELVHAGYLGRKSGRGFYRYGEAAGAPR 301 MD+IGHDVNFAVT SV+ A++ND RF PSLIQQELV AG+ GRKSGRGFY Y E A P Sbjct: 248 MDMIGHDVNFAVTNSVWRAFYNDQRFLPSLIQQELVDAGFYGRKSGRGFYDYREGAVKPE 307 Query: 302 PETERDYPKPTATPQLYGDHPLVEMIHTRYPGQVQRHPARPDQ--LLMKVNAACLCITDG 359 P+TE P ++G+ L E++ R + PD + ++ A L +TDG Sbjct: 308 PQTEA-AQTPAGKITVFGESDLAELLVERLQHSALSYNRAPDSDGRIAEIGFAKLYVTDG 366 Query: 360 RSATLRAWEHQEPDLVLVDLALDYADATRLALAKADQCRPQRYAEVAGVLQACGLDLSPM 419 RSAT RA E + VL+DLALDY+ ATRLA+A A+QC P A G+LQA G +S Sbjct: 367 RSATQRAAETGVANTVLIDLALDYSKATRLAIAAAEQCEPAAVASAVGLLQATGFAVSRF 426 Query: 420 QDVPGMMVMRTVCMLVNEAADAVNQGVCNAADADMAMRKGVNYPRGPLAWANEIGIDTVT 479 DVPG++VMRTV ML NEAADAVNQGVC+ A AD AMR GVNYP+GPLAWA+++G+ + Sbjct: 427 LDVPGLIVMRTVAMLANEAADAVNQGVCSEAGADQAMRLGVNYPQGPLAWADQVGVAAIR 486 Query: 480 QVLHHLCATYGEDRYRISPLLQRLYASGRKFHE 512 VL +L A+YGEDRYRISPL+QR +GR H+ Sbjct: 487 DVLANLGASYGEDRYRISPLIQRAVFAGRNIHD 519 >B5WSW7.1 B5WSW7_9BURK 3-hydroxybutyryl-CoA dehydrogenase EC=1.1.1.157 Length = 519 Score = 545 bits (1405), Expect = e-153, Method: Compositional matrix adjust. Identities = 287/504 (56%), Positives = 358/504 (71%), Gaps = 6/504 (1%) Query: 8 HALSRSALVAVIGSGTMGAGIAQVAAVAGHPVLLYDSREGAAGKAIGAICTNLDKLVSKD 67 +AL S +V ++G+G MGAGIAQVAA+AGH V L+D KAI I NL +LV + Sbjct: 3 NALKTSTIVGIVGAGAMGAGIAQVAALAGHQVALFDLDAATVAKAIKGIAANLARLVDRG 62 Query: 68 KLTPALAQAASQRISVAHSLEELHQADLVIEAIVEQLAAKHELFGKLEAIVSTRCILATN 127 +L A A++R+ L +H A LVIEA+ E+L K ++F +LE V+ CILATN Sbjct: 63 RLDATAAAHANERLVAVDQLAGMHDAGLVIEAVAERLEVKRKIFAELEEHVADACILATN 122 Query: 128 TSSLSITQIAAGLQHPERVVGMHFFNPVPMMALVEIISGLASDAALAQCLHDTALAWGKT 187 TSS+S+T I A L+ P R+VGMHFFNP P+MALVE++SGLA+ A +A C+++TA AWGKT Sbjct: 123 TSSISVTAIGATLRIPSRLVGMHFFNPAPVMALVEVVSGLATSADVATCVYETAAAWGKT 182 Query: 188 PVMARSTPGFIVNRLARPYYAEGLRMLHEGGAQPATIDAVMREAGGFRMGPFELMDLIGH 247 PV ARSTPGFIVNR+ARP+YAEGLR+L+E A A+ID VMREAGGFRMGPFELMDLIGH Sbjct: 183 PVYARSTPGFIVNRVARPFYAEGLRLLNEQAADAASIDEVMREAGGFRMGPFELMDLIGH 242 Query: 248 DVNFAVTQSVFHAYFNDPRFTPSLIQQELVHAGYLGRKSGRGFYRYGEAAGAPRPETERD 307 DVNFAVT+SVF A+FNDPRFTPSLIQQELV+AG+LGRKSGRGFY YG A P P R Sbjct: 243 DVNFAVTESVFRAFFNDPRFTPSLIQQELVNAGFLGRKSGRGFYEYGANATRPNPRIARP 302 Query: 308 YPKPTATPQLYGDHPLVEMIHTRY--PGQVQR---HPARPDQLLMKVNAACLCITDGRSA 362 P +L+ ++E + R G V R D ++ +++ A L +TDGR+A Sbjct: 303 ADSPRVV-KLFPQSGVIERLQQRLRDAGLVTTTMPETERFDGVVAQIDDAVLRLTDGRTA 361 Query: 363 TLRAWEHQEPDLVLVDLALDYADATRLALAKADQCRPQRYAEVAGVLQACGLDLSPMQDV 422 T A++ ++VLVDLALDYA + +AL +A QC YA V G +QA G + P+ DV Sbjct: 362 TQCAYDTDHDNVVLVDLALDYAGGSTVALTRARQCSDSAYAAVVGTMQAAGYSVVPVADV 421 Query: 423 PGMMVMRTVCMLVNEAADAVNQGVCNAADADMAMRKGVNYPRGPLAWANEIGIDTVTQVL 482 GM+VMRTV MLVNEAADAVNQGVC AAD D+AM KGVNYP GPL WA+E G+ VL Sbjct: 422 AGMIVMRTVAMLVNEAADAVNQGVCTAADLDLAMEKGVNYPVGPLQWADEAGVTLFHTVL 481 Query: 483 HHLCATYGEDRYRISPLLQRLYAS 506 ++LC+ YGEDRYR+SPLL L S Sbjct: 482 NNLCSHYGEDRYRVSPLLAALSWS 505 >C7RTA6.1 C7RTA6_ACCPU 3-hydroxybutyryl-CoA dehydrogenase EC=1.1.1.157 Length = 509 Score = 544 bits (1402), Expect = e-152, Method: Compositional matrix adjust. Identities = 288/507 (56%), Positives = 348/507 (68%), Gaps = 4/507 (0%) Query: 8 HALSRSALVAVIGSGTMGAGIAQVAAVAGHPVLLYDSREGAAGKAIGAICTNLDKLVSKD 67 AL+ VA++G+G MG+GIAQVAA AGH VLLYD+ GA +AI I + D+L K Sbjct: 3 QALASDTPVAIVGAGAMGSGIAQVAAAAGHRVLLYDASSGAVEQAIARIGASFDRLAEKG 62 Query: 68 KLTPALAQAASQRISVAHSLEELHQADLVIEAIVEQLAAKHELFGKLEAIVSTRCILATN 127 ++ AQAA R+ A L+EL + L+IEAIVE L AK +LF LEAIVS C+LATN Sbjct: 63 RIDAGAAQAARARLIPAARLDELAASGLLIEAIVEDLVAKQQLFRTLEAIVSPACLLATN 122 Query: 128 TSSLSITQIAAGLQHPERVVGMHFFNPVPMMALVEIISGLASDAALAQCLHDTALAWGKT 187 TSS+S+T IAA L P R+ GMHFFNPVP M LVE+ISGLA++A +A LH TALAWGK+ Sbjct: 123 TSSISVTAIAAALSAPGRLAGMHFFNPVPQMTLVEVISGLATEALVADTLHATALAWGKS 182 Query: 188 PVMARSTPGFIVNRLARPYYAEGLRMLHEGGAQPATIDAVMREAGGFRMGPFELMDLIGH 247 PV ARSTPGFIVNR+ARPYY E LR+L+EG A AT+DAV R AGGFRMGPFELMDLIG Sbjct: 183 PVRARSTPGFIVNRVARPYYGEALRLLNEGAADCATLDAVFRNAGGFRMGPFELMDLIGL 242 Query: 248 DVNFAVTQSVFHAYFNDPRFTPSLIQQELVHAGYLGRKSGRGFYRYGEAAGAPRPETERD 307 DVN AV++SV+ A+FNDPR+ PS IQQE+V AG+LGRKSGRGFY + AA P+ Sbjct: 243 DVNLAVSRSVWSAFFNDPRYAPSPIQQEMVAAGFLGRKSGRGFYPHAPAATMPQAGNLEP 302 Query: 308 YPKPTATPQLYGDHPLVEMIHTRYPGQ---VQRHPARPDQLLMKVNAACLCITDGRSATL 364 P P + ++G+ PL + R + Q PA PD L + A + +TDGRSA+ Sbjct: 303 QPIPCSL-HIFGNCPLASALSERLQVRGLTFQHAPASPDGRLAEAGGAAIYLTDGRSASE 361 Query: 365 RAWEHQEPDLVLVDLALDYADATRLALAKADQCRPQRYAEVAGVLQACGLDLSPMQDVPG 424 R + VLVDLALDY ATRLA+A A+QC G+LQA G +S + DVPG Sbjct: 362 RGARSGVANTVLVDLALDYGSATRLAIATAEQCHAAAATAAVGLLQAAGFTVSRLADVPG 421 Query: 425 MMVMRTVCMLVNEAADAVNQGVCNAADADMAMRKGVNYPRGPLAWANEIGIDTVTQVLHH 484 + +MRTVCML NEAADAV Q VC AA D AMR G NYP GPLAW IG+ V VL + Sbjct: 422 LALMRTVCMLANEAADAVYQNVCTAAAVDQAMRLGTNYPLGPLAWGERIGLPLVHSVLTN 481 Query: 485 LCATYGEDRYRISPLLQRLYASGRKFH 511 L +YGEDRYR SPLL R SG+KFH Sbjct: 482 LATSYGEDRYRASPLLARKVFSGKKFH 508 >Q397D0.1 Q397D0_BURS3 3-hydroxyacyl-CoA dehydrogenase EC=1.1.1.35 Length = 518 Score = 542 bits (1396), Expect = e-152, Method: Compositional matrix adjust. Identities = 281/482 (58%), Positives = 334/482 (69%), Gaps = 10/482 (2%) Query: 37 HPVLLYDSREGAAGKAIGAICTNLDKLVSKDKLTPALAQAASQRISVAHSLEELHQADLV 96 H VLLYD E A KA+ I +L K +L PA A AA RI L + A L+ Sbjct: 41 HTVLLYDLNEAACDKALAGIRAQFARLAEKGRLEPAQADAAGARIRAVRELADFAGAALI 100 Query: 97 IEAIVEQLAAKHELFGKLEAIVSTRCILATNTSSLSITQIAAGLQHPERVVGMHFFNPVP 156 +EA E+L K E+F LE V C+LATNTSS+SIT IAAGL+ P+RV G+HFFNP P Sbjct: 101 VEAAAERLDVKREIFATLERHVDDACLLATNTSSISITSIAAGLRVPQRVAGLHFFNPAP 160 Query: 157 MMALVEIISGLASDAALAQCLHDTALAWGKTPVMARSTPGFIVNRLARPYYAEGLRMLHE 216 +MALVE++SGLA+ +AQ L+ TA AWGK PVMA+STPGFIVNR+ARPYYAE LR+L+E Sbjct: 161 LMALVEVVSGLATAPEVAQVLYATAAAWGKRPVMAKSTPGFIVNRVARPYYAEALRVLNE 220 Query: 217 GGAQPATIDAVMREAGGFRMGPFELMDLIGHDVNFAVTQSVFHAYFNDPRFTPSLIQQEL 276 G PA+IDAVMREAGGFRMGPFELMDLIGHDVNFAVT+SVF AYFNDPR+TPSLIQQEL Sbjct: 221 QGGAPASIDAVMREAGGFRMGPFELMDLIGHDVNFAVTESVFRAYFNDPRYTPSLIQQEL 280 Query: 277 VHAGYLGRKSGRGFYRYGEAAGAPRPETE--RDYPKPTATPQLYGDHPLVEMIHTRY--- 331 V+AG+LGRKSGRGFY Y + A P PE E RD P A L+ + +H R+ Sbjct: 281 VNAGFLGRKSGRGFYSYADGATPPAPELEAPRDAPADVA---LFVEDGPAAALHARFAER 337 Query: 332 -PGQVQRHPARPDQLLMKVNAACLCITDGRSATLRAWEHQEPDLVLVDLALDYADATRLA 390 PG Q A D LL A + +TDGR+AT RA + DLVLVDLA DYA A +A Sbjct: 338 IPGARQAG-AHADDLLATAGRASIALTDGRTATARAAQTGVADLVLVDLARDYAQAGLVA 396 Query: 391 LAKADQCRPQRYAEVAGVLQACGLDLSPMQDVPGMMVMRTVCMLVNEAADAVNQGVCNAA 450 L +A QC YA+ G Q G + + DVPGM+ MRTV ML NEAAD VNQGVC+ A Sbjct: 397 LTRALQCSDAAYADAVGQFQQAGFRVVGVADVPGMVAMRTVAMLANEAADTVNQGVCSPA 456 Query: 451 DADMAMRKGVNYPRGPLAWANEIGIDTVTQVLHHLCATYGEDRYRISPLLQRLYASGRKF 510 D D+AM KGVNYP GPLAWA+ IGI V +VL +L A+YGEDRYR+SPL+ L+A+GR F Sbjct: 457 DLDLAMEKGVNYPCGPLAWADAIGIGRVHRVLSNLAASYGEDRYRVSPLIAALHAAGRTF 516 Query: 511 HE 512 Sbjct: 517 RS 518 >Q1BNS5.1 Q1BNS5_BURCA 3-hydroxyacyl-CoA dehydrogenase EC=1.1.1.35 Length = 518 Score = 540 bits (1392), Expect = e-151, Method: Compositional matrix adjust. Identities = 298/510 (58%), Positives = 359/510 (70%), Gaps = 10/510 (1%) Query: 9 ALSRSALVAVIGSGTMGAGIAQVAAVAGHPVLLYDSREGAAGKAIGAICTNLDKLVSKDK 68 AL+ SA+V VIG+G MGAGIAQVAA AGH VLLYD E A KA+ I +L K + Sbjct: 13 ALAPSAVVGVIGAGAMGAGIAQVAAAAGHAVLLYDLNEAACDKALAGIRAQFARLAEKGR 72 Query: 69 LTPALAQAASQRISVAHSLEELHQADLVIEAIVEQLAAKHELFGKLEAIVSTRCILATNT 128 L PA A AA R+ +L + A L++EA E+L K E+F LE V C+LATNT Sbjct: 73 LEPAQADAAGNRLRAVRALADFAGAALIVEAAAERLDVKREIFATLERHVDDACVLATNT 132 Query: 129 SSLSITQIAAGLQHPERVVGMHFFNPVPMMALVEIISGLASDAALAQCLHDTALAWGKTP 188 SS+SIT IAAGL+ P+RV G+HFFNP P+MALVE++SGLA+ +A LH TA AWGK P Sbjct: 133 SSISITSIAAGLRVPQRVAGLHFFNPAPLMALVEVVSGLATAPEVAGMLHATAAAWGKQP 192 Query: 189 VMARSTPGFIVNRLARPYYAEGLRMLHEGGAQPATIDAVMREAGGFRMGPFELMDLIGHD 248 VMA+STPGFIVNR+ARPYYAE LR+L+E G PATIDAVMREAGGFRMGPFELMDLIGHD Sbjct: 193 VMAKSTPGFIVNRVARPYYAEALRVLNEQGGTPATIDAVMREAGGFRMGPFELMDLIGHD 252 Query: 249 VNFAVTQSVFHAYFNDPRFTPSLIQQELVHAGYLGRKSGRGFYRYGEAAGAPRPETERDY 308 VNFAVT+SVF AYFNDPR+TPSLIQQELV+AG+LGRKSGRGFY Y + A P P+ E Sbjct: 253 VNFAVTESVFRAYFNDPRYTPSLIQQELVNAGFLGRKSGRGFYSYADGATPPAPDLE--- 309 Query: 309 PKPTATPQ---LYGDHPLVEMIHTRYPGQVQ---RHPARPDQLLMKVNAACLCITDGRSA 362 P A P L+ +HTR +++ R+ A D+LL A + +TDGR+A Sbjct: 310 -PPRAAPADVVLFAQEGPAAALHTRLAERIEGARRNGAHADELLAVAGRASIALTDGRTA 368 Query: 363 TLRAWEHQEPDLVLVDLALDYADATRLALAKADQCRPQRYAEVAGVLQACGLDLSPMQDV 422 T RA + DLVLVDLA DYA A +AL +A QC YA+ G+ Q G + + DV Sbjct: 369 TARAAQTGVADLVLVDLARDYAQAGLVALTRALQCNDAAYADAVGLFQQAGFRVVGIADV 428 Query: 423 PGMMVMRTVCMLVNEAADAVNQGVCNAADADMAMRKGVNYPRGPLAWANEIGIDTVTQVL 482 PGM+ MRTV ML NEAAD VNQGVC+ AD D+AM KGVNYP GPLAWA+ IGI V +VL Sbjct: 429 PGMVAMRTVAMLANEAADTVNQGVCSPADLDLAMEKGVNYPCGPLAWADAIGIGRVHRVL 488 Query: 483 HHLCATYGEDRYRISPLLQRLYASGRKFHE 512 +L A+YGEDRYR+SP + L+A+GR F Sbjct: 489 SNLAASYGEDRYRVSPRVAALHAAGRTFRS 518 >A0B0T8.1 A0B0T8_BURCH 3-hydroxyacyl-CoA dehydrogenase EC=1.1.1.35 Length = 518 Score = 540 bits (1392), Expect = e-151, Method: Compositional matrix adjust. Identities = 298/510 (58%), Positives = 359/510 (70%), Gaps = 10/510 (1%) Query: 9 ALSRSALVAVIGSGTMGAGIAQVAAVAGHPVLLYDSREGAAGKAIGAICTNLDKLVSKDK 68 AL+ SA+V VIG+G MGAGIAQVAA AGH VLLYD E A KA+ I +L K + Sbjct: 13 ALAPSAVVGVIGAGAMGAGIAQVAAAAGHAVLLYDLNEAACDKALAGIRAQFARLAEKGR 72 Query: 69 LTPALAQAASQRISVAHSLEELHQADLVIEAIVEQLAAKHELFGKLEAIVSTRCILATNT 128 L PA A AA R+ +L + A L++EA E+L K E+F LE V C+LATNT Sbjct: 73 LEPAQADAAGNRLRAVRALADFAGAALIVEAAAERLDVKREIFATLERHVDDACVLATNT 132 Query: 129 SSLSITQIAAGLQHPERVVGMHFFNPVPMMALVEIISGLASDAALAQCLHDTALAWGKTP 188 SS+SIT IAAGL+ P+RV G+HFFNP P+MALVE++SGLA+ +A LH TA AWGK P Sbjct: 133 SSISITSIAAGLRVPQRVAGLHFFNPAPLMALVEVVSGLATAPEVAGMLHATAAAWGKQP 192 Query: 189 VMARSTPGFIVNRLARPYYAEGLRMLHEGGAQPATIDAVMREAGGFRMGPFELMDLIGHD 248 VMA+STPGFIVNR+ARPYYAE LR+L+E G PATIDAVMREAGGFRMGPFELMDLIGHD Sbjct: 193 VMAKSTPGFIVNRVARPYYAEALRVLNEQGGTPATIDAVMREAGGFRMGPFELMDLIGHD 252 Query: 249 VNFAVTQSVFHAYFNDPRFTPSLIQQELVHAGYLGRKSGRGFYRYGEAAGAPRPETERDY 308 VNFAVT+SVF AYFNDPR+TPSLIQQELV+AG+LGRKSGRGFY Y + A P P+ E Sbjct: 253 VNFAVTESVFRAYFNDPRYTPSLIQQELVNAGFLGRKSGRGFYSYADGATPPAPDLE--- 309 Query: 309 PKPTATPQ---LYGDHPLVEMIHTRYPGQVQ---RHPARPDQLLMKVNAACLCITDGRSA 362 P A P L+ +HTR +++ R+ A D+LL A + +TDGR+A Sbjct: 310 -PPRAAPADVVLFAQEGPAAALHTRLAERIEGARRNGAHADELLAVAGRASIALTDGRTA 368 Query: 363 TLRAWEHQEPDLVLVDLALDYADATRLALAKADQCRPQRYAEVAGVLQACGLDLSPMQDV 422 T RA + DLVLVDLA DYA A +AL +A QC YA+ G+ Q G + + DV Sbjct: 369 TARAAQTGVADLVLVDLARDYAQAGLVALTRALQCNDAAYADAVGLFQQAGFRVVGIADV 428 Query: 423 PGMMVMRTVCMLVNEAADAVNQGVCNAADADMAMRKGVNYPRGPLAWANEIGIDTVTQVL 482 PGM+ MRTV ML NEAAD VNQGVC+ AD D+AM KGVNYP GPLAWA+ IGI V +VL Sbjct: 429 PGMVAMRTVAMLANEAADTVNQGVCSPADLDLAMEKGVNYPCGPLAWADAIGIGRVHRVL 488 Query: 483 HHLCATYGEDRYRISPLLQRLYASGRKFHE 512 +L A+YGEDRYR+SP + L+A+GR F Sbjct: 489 SNLAASYGEDRYRVSPRVAALHAAGRTFRS 518 >B1K3L1.1 B1K3L1_BURCC 3-hydroxybutyryl-CoA dehydrogenase EC=1.1.1.157 Length = 518 Score = 540 bits (1390), Expect = e-151, Method: Compositional matrix adjust. Identities = 274/477 (57%), Positives = 331/477 (69%), Gaps = 4/477 (0%) Query: 39 VLLYDSREGAAGKAIGAICTNLDKLVSKDKLTPALAQAASQRISVAHSLEELHQADLVIE 98 VLLYD E A KA+ I +L K +L PA A AA RI +L + A L++E Sbjct: 43 VLLYDLNEAACDKALAGIRAQFARLAEKGRLEPAQADAAGNRIRAVRALADFAGAALIVE 102 Query: 99 AIVEQLAAKHELFGKLEAIVSTRCILATNTSSLSITQIAAGLQHPERVVGMHFFNPVPMM 158 A E+L K E+F LE V C+LATNTSS+SIT IAAGL+ P+RV G+HFFNP P+M Sbjct: 103 AAAERLDVKREIFATLERHVDDACVLATNTSSISITSIAAGLRVPQRVAGLHFFNPAPLM 162 Query: 159 ALVEIISGLASDAALAQCLHDTALAWGKTPVMARSTPGFIVNRLARPYYAEGLRMLHEGG 218 ALVE++SGLA+ +A LH TA AWGK PVMA+STPGFIVNR+ARPYYAE LR+L+E G Sbjct: 163 ALVEVVSGLATAPEVAGMLHATAAAWGKQPVMAKSTPGFIVNRVARPYYAEALRVLNEQG 222 Query: 219 AQPATIDAVMREAGGFRMGPFELMDLIGHDVNFAVTQSVFHAYFNDPRFTPSLIQQELVH 278 PA+IDAVMREAGGFRMGPFELMDLIGHDVNFAVT+SVF AYFNDPR+TPSLIQQELV+ Sbjct: 223 GAPASIDAVMREAGGFRMGPFELMDLIGHDVNFAVTESVFRAYFNDPRYTPSLIQQELVN 282 Query: 279 AGYLGRKSGRGFYRYGEAAGAPRPETERDYPKPTATPQLYGDHPLVEMIHTRYPGQVQ-- 336 AG+LGRKSGRGFY Y + A P P+ E P D P +H R +++ Sbjct: 283 AGFLGRKSGRGFYSYADGATTPAPDLEPPRAAPAEIALFAQDGP-AAALHARLAERIEGA 341 Query: 337 -RHPARPDQLLMKVNAACLCITDGRSATLRAWEHQEPDLVLVDLALDYADATRLALAKAD 395 R+ A D+LL A + +TDGR+AT RA + DLVLVDLA DYA A +AL +A Sbjct: 342 RRNGAHADELLAVAGRASIALTDGRTATARAAQTGVADLVLVDLARDYAQAGLVALTRAL 401 Query: 396 QCRPQRYAEVAGVLQACGLDLSPMQDVPGMMVMRTVCMLVNEAADAVNQGVCNAADADMA 455 QC YA+ G+ Q G + + DVPGM+ MRTV ML NEAAD VNQGVC+ AD D+A Sbjct: 402 QCNDAAYADAVGLFQQAGFRVVGIADVPGMVAMRTVAMLANEAADTVNQGVCSPADLDLA 461 Query: 456 MRKGVNYPRGPLAWANEIGIDTVTQVLHHLCATYGEDRYRISPLLQRLYASGRKFHE 512 M KGVNYP GPLAWA+ IGI V +VL +L A+YGEDRYR+SP + L+A+GR F Sbjct: 462 MEKGVNYPCGPLAWADAIGIGRVHRVLSNLAASYGEDRYRVSPRVAALHAAGRTFRS 518 >A4JP17.1 A4JP17_BURVG 3-hydroxyacyl-CoA dehydrogenase EC=1.1.1.35 Length = 517 Score = 539 bits (1389), Expect = e-151, Method: Compositional matrix adjust. Identities = 299/506 (59%), Positives = 360/506 (71%), Gaps = 4/506 (0%) Query: 9 ALSRSALVAVIGSGTMGAGIAQVAAVAGHPVLLYDSREGAAGKAIGAICTNLDKLVSKDK 68 AL+ SALV VIG+G MGAGIAQVAA AGH VLLYD E A KA+ I +L K + Sbjct: 13 ALAPSALVGVIGAGAMGAGIAQVAAAAGHTVLLYDLDEAACDKALAGIRAQFARLAEKGR 72 Query: 69 LTPALAQAASQRISVAHSLEELHQADLVIEAIVEQLAAKHELFGKLEAIVSTRCILATNT 128 L PA A AA RI +L E A L++EA E+L K E+F LE V RC+LATNT Sbjct: 73 LEPAQADAAGSRIRAVRALAEFAGAALIVEAAAERLDVKREIFATLERHVDERCVLATNT 132 Query: 129 SSLSITQIAAGLQHPERVVGMHFFNPVPMMALVEIISGLASDAALAQCLHDTALAWGKTP 188 SS+SIT IAAGL+ P+RV G+HFFNP P+MALVE++SGLA+ A +AQ L+DTA AWGK P Sbjct: 133 SSISITSIAAGLRAPQRVAGLHFFNPAPLMALVEVVSGLATAAEVAQLLYDTAAAWGKRP 192 Query: 189 VMARSTPGFIVNRLARPYYAEGLRMLHEGGAQPATIDAVMREAGGFRMGPFELMDLIGHD 248 VMA+STPGFIVNR+ARPYYAE LR+L+E G PA+IDAVMR+AGGFRMGPFELMDLIGHD Sbjct: 193 VMAKSTPGFIVNRVARPYYAEALRVLNEQGGTPASIDAVMRDAGGFRMGPFELMDLIGHD 252 Query: 249 VNFAVTQSVFHAYFNDPRFTPSLIQQELVHAGYLGRKSGRGFYRYGEAAGAPRPETERDY 308 VNFAVT+SVF AYFNDPR+TPSLIQQELV+AG+LGRKSGRGFY Y A P PE E Sbjct: 253 VNFAVTESVFRAYFNDPRYTPSLIQQELVNAGFLGRKSGRGFYSYAPDAPPPAPEFEAPC 312 Query: 309 PKPTATPQLYGDHPLVEMIHTRYPGQV---QRHPARPDQLLMKVNAACLCITDGRSATLR 365 P + P V + H R+ ++ +++ A D+L+ A + +TDGR+ATLR Sbjct: 313 VAPADVVLFEQEGPAVAL-HARFAERIPNARQNGAHADELIAVAGRASIALTDGRTATLR 371 Query: 366 AWEHQEPDLVLVDLALDYADATRLALAKADQCRPQRYAEVAGVLQACGLDLSPMQDVPGM 425 A + DLVLVDLA DYA A +AL +A QC YA+ G+ Q G + + DVPGM Sbjct: 372 AAQTGVADLVLVDLARDYARAGLVALTRALQCSDAAYADAVGLFQQAGFRVVGVGDVPGM 431 Query: 426 MVMRTVCMLVNEAADAVNQGVCNAADADMAMRKGVNYPRGPLAWANEIGIDTVTQVLHHL 485 + MRTV ML NEAAD VNQGVC+ AD D+AM KGVNYP GPL WA+ IGI V +VL HL Sbjct: 432 VAMRTVAMLANEAADTVNQGVCSPADLDLAMEKGVNYPCGPLTWADAIGIGRVHRVLSHL 491 Query: 486 CATYGEDRYRISPLLQRLYASGRKFH 511 +YGEDRYR+SP + L+A+GR F Sbjct: 492 ATSYGEDRYRVSPRIAALHAAGRTFR 517 >A2VYH9.1 A2VYH9_9BURK 3-hydroxybutyryl-CoA dehydrogenase Length = 518 Score = 539 bits (1389), Expect = e-151, Method: Compositional matrix adjust. Identities = 274/477 (57%), Positives = 331/477 (69%), Gaps = 4/477 (0%) Query: 39 VLLYDSREGAAGKAIGAICTNLDKLVSKDKLTPALAQAASQRISVAHSLEELHQADLVIE 98 VLLYD E A KA+ I +L K +L PA A AA R+ +L + A L++E Sbjct: 43 VLLYDLNEAACDKALAGIRAQFARLAEKGRLEPAQADAAGNRLRAVRALADFAGAALIVE 102 Query: 99 AIVEQLAAKHELFGKLEAIVSTRCILATNTSSLSITQIAAGLQHPERVVGMHFFNPVPMM 158 A E+L K E+F LE V C+LATNTSS+SIT IAAGL+ P+RV G+HFFNP P+M Sbjct: 103 AAAERLDVKREIFATLERHVDDACVLATNTSSISITSIAAGLRVPQRVAGLHFFNPAPLM 162 Query: 159 ALVEIISGLASDAALAQCLHDTALAWGKTPVMARSTPGFIVNRLARPYYAEGLRMLHEGG 218 ALVE++SGLA+ +A LH TA AWGK PVMA+STPGFIVNR+ARPYYAE LR+L+E G Sbjct: 163 ALVEVVSGLATAPEVAGMLHATAAAWGKQPVMAKSTPGFIVNRVARPYYAEALRVLNEQG 222 Query: 219 AQPATIDAVMREAGGFRMGPFELMDLIGHDVNFAVTQSVFHAYFNDPRFTPSLIQQELVH 278 PATIDAVMREAGGFRMGPFELMDLIGHDVNFAVT+SVF AYFNDPR+TPSLIQQELV+ Sbjct: 223 GTPATIDAVMREAGGFRMGPFELMDLIGHDVNFAVTESVFRAYFNDPRYTPSLIQQELVN 282 Query: 279 AGYLGRKSGRGFYRYGEAAGAPRPETERDYPKPTATPQLYGDHPLVEMIHTRYPGQVQ-- 336 AG+LGRKSGRGFY Y + A P P+ E P D P +H R +++ Sbjct: 283 AGFLGRKSGRGFYSYADGATPPAPDLEPPRAAPAEIALFAQDGP-AAALHARLAERIEGA 341 Query: 337 -RHPARPDQLLMKVNAACLCITDGRSATLRAWEHQEPDLVLVDLALDYADATRLALAKAD 395 R+ A D+LL A + +TDGR+AT RA + DLVLVDLA DYA A +AL +A Sbjct: 342 RRNGAHADELLAVAGRASIALTDGRTATARAAQTGVADLVLVDLARDYAQAGLVALTRAL 401 Query: 396 QCRPQRYAEVAGVLQACGLDLSPMQDVPGMMVMRTVCMLVNEAADAVNQGVCNAADADMA 455 QC YA+ G+ Q G + + DVPGM+ MRTV ML NEAAD VNQGVC+ AD D+A Sbjct: 402 QCNDAAYADAVGLFQQAGFRVVGIADVPGMVAMRTVAMLANEAADTVNQGVCSPADLDLA 461 Query: 456 MRKGVNYPRGPLAWANEIGIDTVTQVLHHLCATYGEDRYRISPLLQRLYASGRKFHE 512 M KGVNYP GPLAWA+ IGI V +VL +L A+YGEDRYR+SP + L+A+GR F Sbjct: 462 MEKGVNYPCGPLAWADAIGIGRVHRVLSNLAASYGEDRYRVSPRVAALHAAGRTFRS 518