BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0089.p (254 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8ISW7.1 D8ISW7_HERSS Imidazole glycerol phosphate synthase subu... 507 e-142 A6T376.1 HIS6_JANMA Imidazole glycerol phosphate synthase subuni... 462 e-128 A4G9I6.1 HIS6_HERAR Imidazole glycerol phosphate synthase subuni... 459 e-127 F1W3Z5.1 F1W3Z5_9BURK Imidazole glycerol phosphate synthase cycl... 442 e-122 D5W543.1 D5W543_BURSC Imidazole glycerol phosphate synthase subu... 441 e-122 D5NGP3.1 D5NGP3_9BURK Imidazole glycerol phosphate synthase subu... 441 e-122 B2JHX9.1 HIS6_BURP8 Imidazole glycerol phosphate synthase subuni... 438 e-121 A4JAW9.1 HIS6_BURVG Imidazole glycerol phosphate synthase subuni... 438 e-121 B2SZ59.1 HIS6_BURPP Imidazole glycerol phosphate synthase subuni... 438 e-121 E8YGL4.1 E8YGL4_9BURK Imidazole glycerol phosphate synthase subu... 438 e-121 >D8ISW7.1 D8ISW7_HERSS Imidazole glycerol phosphate synthase subunit hisF EC=4.1.3.- Length = 254 Score = 507 bits (1305), Expect = e-142, Method: Compositional matrix adjust. Identities = 254/254 (100%), Positives = 254/254 (100%) Query: 1 MALAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADELTFLDITASSDGR 60 MALAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADELTFLDITASSDGR Sbjct: 1 MALAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADELTFLDITASSDGR 60 Query: 61 DLILDIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVGINTSAVTNPQLVADAASK 120 DLILDIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVGINTSAVTNPQLVADAASK Sbjct: 61 DLILDIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVGINTSAVTNPQLVADAASK 120 Query: 121 YGSQCIVVAIDAKRAGDGKWEVYTHGGRKATGLDAVEWARKMAQLGAGEILLTSMDRDGT 180 YGSQCIVVAIDAKRAGDGKWEVYTHGGRKATGLDAVEWARKMAQLGAGEILLTSMDRDGT Sbjct: 121 YGSQCIVVAIDAKRAGDGKWEVYTHGGRKATGLDAVEWARKMAQLGAGEILLTSMDRDGT 180 Query: 181 KSGFDLDLTRAVSEAVSIPVIASGGVGGLQDLADGITKGKADAVLAASIFHYGQHTVQEA 240 KSGFDLDLTRAVSEAVSIPVIASGGVGGLQDLADGITKGKADAVLAASIFHYGQHTVQEA Sbjct: 181 KSGFDLDLTRAVSEAVSIPVIASGGVGGLQDLADGITKGKADAVLAASIFHYGQHTVQEA 240 Query: 241 KRFMADQNISMRLA 254 KRFMADQNISMRLA Sbjct: 241 KRFMADQNISMRLA 254 >A6T376.1 HIS6_JANMA Imidazole glycerol phosphate synthase subunit hisF EC=4.1.3.- Length = 254 Score = 462 bits (1189), Expect = e-128, Method: Compositional matrix adjust. Identities = 225/253 (88%), Positives = 242/253 (95%) Query: 1 MALAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADELTFLDITASSDGR 60 M LAKRIIPCLDVTAGRVVKGVNFLELRDAGDP+EIARRYDEQGADE+TFLDITA+SDGR Sbjct: 1 MTLAKRIIPCLDVTAGRVVKGVNFLELRDAGDPIEIARRYDEQGADEITFLDITATSDGR 60 Query: 61 DLILDIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVGINTSAVTNPQLVADAASK 120 DLILDIIEAVASQVFIPLTVGGGVRAV+DVRRLLNAGADKVGIN+SA++NPQLV DA+ K Sbjct: 61 DLILDIIEAVASQVFIPLTVGGGVRAVDDVRRLLNAGADKVGINSSAISNPQLVFDASQK 120 Query: 121 YGSQCIVVAIDAKRAGDGKWEVYTHGGRKATGLDAVEWARKMAQLGAGEILLTSMDRDGT 180 YGSQCIVVAIDAK+A DG+WEV+THGGRKATGLDAVEWA+KM LGAGEILLTSMDRDGT Sbjct: 121 YGSQCIVVAIDAKKASDGRWEVFTHGGRKATGLDAVEWAKKMQNLGAGEILLTSMDRDGT 180 Query: 181 KSGFDLDLTRAVSEAVSIPVIASGGVGGLQDLADGITKGKADAVLAASIFHYGQHTVQEA 240 K GFDLDLTR+VS+A+SIPVIASGGVGGLQDLADG+ G+ADAVLAASIFHYGQHTVQEA Sbjct: 181 KIGFDLDLTRSVSDAISIPVIASGGVGGLQDLADGVKVGRADAVLAASIFHYGQHTVQEA 240 Query: 241 KRFMADQNISMRL 253 KRFMADQ I MRL Sbjct: 241 KRFMADQGIPMRL 253 >A4G9I6.1 HIS6_HERAR Imidazole glycerol phosphate synthase subunit hisF EC=4.1.3.- Length = 254 Score = 459 bits (1180), Expect = e-127, Method: Compositional matrix adjust. Identities = 222/253 (87%), Positives = 242/253 (95%) Query: 1 MALAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADELTFLDITASSDGR 60 M LAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYD+QGADELTFLDITA+SDGR Sbjct: 1 MTLAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDDQGADELTFLDITATSDGR 60 Query: 61 DLILDIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVGINTSAVTNPQLVADAASK 120 DLILDIIEAVASQVFIPLTVGGGVRAV+DVRRLLNAGADKVGIN+SA++NPQLV DA+ K Sbjct: 61 DLILDIIEAVASQVFIPLTVGGGVRAVDDVRRLLNAGADKVGINSSAISNPQLVFDASQK 120 Query: 121 YGSQCIVVAIDAKRAGDGKWEVYTHGGRKATGLDAVEWARKMAQLGAGEILLTSMDRDGT 180 YGSQCIVVAIDAK+A DG+WEV+THGGRKATGLDA+EWA+KM LGAGEILLTSMDRDGT Sbjct: 121 YGSQCIVVAIDAKKAADGRWEVFTHGGRKATGLDAIEWAKKMESLGAGEILLTSMDRDGT 180 Query: 181 KSGFDLDLTRAVSEAVSIPVIASGGVGGLQDLADGITKGKADAVLAASIFHYGQHTVQEA 240 K GFDLDLTR+VS+A+SIPVIASGGVGGLQDL DG+ G+ADAVLAASIFHYGQHTVQEA Sbjct: 181 KVGFDLDLTRSVSDAISIPVIASGGVGGLQDLVDGVKIGRADAVLAASIFHYGQHTVQEA 240 Query: 241 KRFMADQNISMRL 253 KRFM++Q I+MRL Sbjct: 241 KRFMSEQGIAMRL 253 >F1W3Z5.1 F1W3Z5_9BURK Imidazole glycerol phosphate synthase cyclase subunit Length = 254 Score = 442 bits (1137), Expect = e-122, Method: Compositional matrix adjust. Identities = 215/253 (84%), Positives = 235/253 (92%) Query: 1 MALAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADELTFLDITASSDGR 60 M LAKRIIPCLDVTAGRVVKG+NFLELRDAGDPVEIARRYDEQGADE+TFLDITA+SDGR Sbjct: 1 MTLAKRIIPCLDVTAGRVVKGINFLELRDAGDPVEIARRYDEQGADEITFLDITATSDGR 60 Query: 61 DLILDIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVGINTSAVTNPQLVADAASK 120 DLIL IIEAVAS VFIPLTVGGGVR VEDVRRLLNAGADKV IN+SA++NPQLV DAA K Sbjct: 61 DLILHIIEAVASTVFIPLTVGGGVRVVEDVRRLLNAGADKVSINSSAISNPQLVFDAAQK 120 Query: 121 YGSQCIVVAIDAKRAGDGKWEVYTHGGRKATGLDAVEWARKMAQLGAGEILLTSMDRDGT 180 +GSQCIVVAIDAKR+GDGKWEV+THGGRKATGLD +EWA+KMA GAGE+LLTSMDRDGT Sbjct: 121 HGSQCIVVAIDAKRSGDGKWEVFTHGGRKATGLDVIEWAKKMAAFGAGELLLTSMDRDGT 180 Query: 181 KSGFDLDLTRAVSEAVSIPVIASGGVGGLQDLADGITKGKADAVLAASIFHYGQHTVQEA 240 +SGFDL LT AVS+AV+IPVIASGGVGGLQDLADG+ GKADAVLAASIFHYG HT+ EA Sbjct: 181 RSGFDLALTAAVSDAVNIPVIASGGVGGLQDLADGVKIGKADAVLAASIFHYGHHTIAEA 240 Query: 241 KRFMADQNISMRL 253 K+FMA Q I++RL Sbjct: 241 KQFMAAQQIAVRL 253 >D5W543.1 D5W543_BURSC Imidazole glycerol phosphate synthase subunit hisF EC=4.1.3.- Length = 257 Score = 441 bits (1134), Expect = e-122, Method: Compositional matrix adjust. Identities = 224/257 (87%), Positives = 236/257 (91%), Gaps = 4/257 (1%) Query: 1 MALAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADELTFLDITASSDGR 60 MALAKRIIPCLDVTAGRVVKGVNF+ELRDAGDPVEIARRYD+QGADELTFLDITA+SD R Sbjct: 1 MALAKRIIPCLDVTAGRVVKGVNFVELRDAGDPVEIARRYDDQGADELTFLDITATSDQR 60 Query: 61 DLILDIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVGINTSAVTNPQLVADAASK 120 DLIL IIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADK+ +N+SAV NPQLV DA K Sbjct: 61 DLILPIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKISMNSSAVANPQLVKDATDK 120 Query: 121 YGSQCIVVAIDAKR-AGDG---KWEVYTHGGRKATGLDAVEWARKMAQLGAGEILLTSMD 176 YGSQCIVVAIDAKR + DG +WEV+THGGRKATGLDAVEWARKMAQLGAGEILLTSMD Sbjct: 121 YGSQCIVVAIDAKRVSADGETPRWEVFTHGGRKATGLDAVEWARKMAQLGAGEILLTSMD 180 Query: 177 RDGTKSGFDLDLTRAVSEAVSIPVIASGGVGGLQDLADGITKGKADAVLAASIFHYGQHT 236 RDGTKSGFDL LTRAVS+AV IPVIASGGVG LQ LADGI G ADAVLAASIFHYG+HT Sbjct: 181 RDGTKSGFDLALTRAVSDAVPIPVIASGGVGNLQHLADGIKSGHADAVLAASIFHYGEHT 240 Query: 237 VQEAKRFMADQNISMRL 253 V EAKRFMADQ IS+RL Sbjct: 241 VGEAKRFMADQGISVRL 257 >D5NGP3.1 D5NGP3_9BURK Imidazole glycerol phosphate synthase subunit hisF EC=4.1.3.- Length = 257 Score = 441 bits (1133), Expect = e-122, Method: Compositional matrix adjust. Identities = 223/257 (86%), Positives = 238/257 (92%), Gaps = 4/257 (1%) Query: 1 MALAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADELTFLDITASSDGR 60 MALAKRIIPCLDVTAGRVVKGVNF+ELRDAGDPVEIARRYD+QGADELTFLDITA+SD R Sbjct: 1 MALAKRIIPCLDVTAGRVVKGVNFVELRDAGDPVEIARRYDDQGADELTFLDITATSDQR 60 Query: 61 DLILDIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVGINTSAVTNPQLVADAASK 120 DLIL IIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADK+ +N+SAV NPQLV DA K Sbjct: 61 DLILPIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKISMNSSAVANPQLVKDATDK 120 Query: 121 YGSQCIVVAIDAKR---AGDG-KWEVYTHGGRKATGLDAVEWARKMAQLGAGEILLTSMD 176 YGSQCIVVAIDAKR AG+ +WEV+THGGRKATGLDAVEWARKMA+LGAGEILLTSMD Sbjct: 121 YGSQCIVVAIDAKRVSAAGEAPRWEVFTHGGRKATGLDAVEWARKMAELGAGEILLTSMD 180 Query: 177 RDGTKSGFDLDLTRAVSEAVSIPVIASGGVGGLQDLADGITKGKADAVLAASIFHYGQHT 236 RDGTKSGFDL LTRAVS+AV IPVIASGGVG LQ LADGI +G+ADAVLAASIFHYG+HT Sbjct: 181 RDGTKSGFDLALTRAVSDAVPIPVIASGGVGNLQHLADGIKEGRADAVLAASIFHYGEHT 240 Query: 237 VQEAKRFMADQNISMRL 253 V EAKRFMADQ IS+RL Sbjct: 241 VGEAKRFMADQGISVRL 257 >B2JHX9.1 HIS6_BURP8 Imidazole glycerol phosphate synthase subunit hisF EC=4.1.3.- Length = 257 Score = 438 bits (1127), Expect = e-121, Method: Compositional matrix adjust. Identities = 221/257 (85%), Positives = 238/257 (92%), Gaps = 4/257 (1%) Query: 1 MALAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADELTFLDITASSDGR 60 MALAKRIIPCLDVTAGRVVKGVNF+ELRDAGDPVEIARRYDEQGADELTFLDITA+SD R Sbjct: 1 MALAKRIIPCLDVTAGRVVKGVNFVELRDAGDPVEIARRYDEQGADELTFLDITATSDQR 60 Query: 61 DLILDIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVGINTSAVTNPQLVADAASK 120 DLIL IIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKV +N+SAV NPQLV D+ K Sbjct: 61 DLILPIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVSMNSSAVANPQLVRDSTDK 120 Query: 121 YGSQCIVVAIDAKR-AGDG---KWEVYTHGGRKATGLDAVEWARKMAQLGAGEILLTSMD 176 YGSQCIVVAIDAKR + +G +WEV+THGGRK TGLDAVEWAR+MA+LGAGEILLTSMD Sbjct: 121 YGSQCIVVAIDAKRVSAEGETPRWEVFTHGGRKNTGLDAVEWARRMAELGAGEILLTSMD 180 Query: 177 RDGTKSGFDLDLTRAVSEAVSIPVIASGGVGGLQDLADGITKGKADAVLAASIFHYGQHT 236 RDGTKSGFD+ LTRAVS+AVSIPVIASGGVG LQ LADGIT+G+ADAVLAASIFHYG+HT Sbjct: 181 RDGTKSGFDIALTRAVSDAVSIPVIASGGVGSLQHLADGITQGRADAVLAASIFHYGEHT 240 Query: 237 VQEAKRFMADQNISMRL 253 V E KRFMADQ IS+RL Sbjct: 241 VGECKRFMADQGISVRL 257 >A4JAW9.1 HIS6_BURVG Imidazole glycerol phosphate synthase subunit hisF EC=4.1.3.- Length = 257 Score = 438 bits (1127), Expect = e-121, Method: Compositional matrix adjust. Identities = 221/257 (85%), Positives = 235/257 (91%), Gaps = 4/257 (1%) Query: 1 MALAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADELTFLDITASSDGR 60 MALAKRIIPCLDVTAGRVVKGVNF+ELRDAGDPVEIARRYDEQGADELTFLDITA+SD R Sbjct: 1 MALAKRIIPCLDVTAGRVVKGVNFVELRDAGDPVEIARRYDEQGADELTFLDITATSDQR 60 Query: 61 DLILDIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVGINTSAVTNPQLVADAASK 120 DLIL IIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKV +N+SAV NPQLV DAA K Sbjct: 61 DLILPIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVSMNSSAVANPQLVRDAADK 120 Query: 121 YGSQCIVVAIDAKRAG----DGKWEVYTHGGRKATGLDAVEWARKMAQLGAGEILLTSMD 176 YGSQCIVVAIDAKR +WEV+THGGRKATGLDA+EWARKMA+LGAGEILLTSMD Sbjct: 121 YGSQCIVVAIDAKRVSAPNEAPRWEVFTHGGRKATGLDAIEWARKMAELGAGEILLTSMD 180 Query: 177 RDGTKSGFDLDLTRAVSEAVSIPVIASGGVGGLQDLADGITKGKADAVLAASIFHYGQHT 236 RDGTKSGFDL LTRAVS+AV +PVIASGGVG LQDLADGI +G ADAVLAASIFHYG+HT Sbjct: 181 RDGTKSGFDLALTRAVSDAVPVPVIASGGVGCLQDLADGIKQGHADAVLAASIFHYGEHT 240 Query: 237 VQEAKRFMADQNISMRL 253 V EAK FMADQ I++RL Sbjct: 241 VGEAKHFMADQGIAVRL 257 >B2SZ59.1 HIS6_BURPP Imidazole glycerol phosphate synthase subunit hisF EC=4.1.3.- Length = 257 Score = 438 bits (1126), Expect = e-121, Method: Compositional matrix adjust. Identities = 222/257 (86%), Positives = 236/257 (91%), Gaps = 4/257 (1%) Query: 1 MALAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADELTFLDITASSDGR 60 MALAKRIIPCLDVTAGRVVKGVNF+ELRDAGDPVEIARRYD+QGADELTFLDITA+SD R Sbjct: 1 MALAKRIIPCLDVTAGRVVKGVNFVELRDAGDPVEIARRYDDQGADELTFLDITATSDQR 60 Query: 61 DLILDIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVGINTSAVTNPQLVADAASK 120 DLIL IIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADK+ +N+SAV NPQLV DA K Sbjct: 61 DLILPIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKISMNSSAVANPQLVKDATDK 120 Query: 121 YGSQCIVVAIDAKR-AGDG---KWEVYTHGGRKATGLDAVEWARKMAQLGAGEILLTSMD 176 YGSQCIVVAIDAKR + DG +WEV+THGGRKATGL+AVEWARKMA+LGAGEILLTSMD Sbjct: 121 YGSQCIVVAIDAKRVSADGEPPRWEVFTHGGRKATGLEAVEWARKMAELGAGEILLTSMD 180 Query: 177 RDGTKSGFDLDLTRAVSEAVSIPVIASGGVGGLQDLADGITKGKADAVLAASIFHYGQHT 236 RDGTKSGFDL LTRAVS+AV IPVIASGGVG LQ LADGI G ADAVLAASIFHYG+HT Sbjct: 181 RDGTKSGFDLALTRAVSDAVPIPVIASGGVGNLQHLADGIKNGHADAVLAASIFHYGEHT 240 Query: 237 VQEAKRFMADQNISMRL 253 V EAKRFMADQ IS+RL Sbjct: 241 VGEAKRFMADQGISVRL 257 >E8YGL4.1 E8YGL4_9BURK Imidazole glycerol phosphate synthase subunit hisF EC=4.1.3.- Length = 257 Score = 438 bits (1126), Expect = e-121, Method: Compositional matrix adjust. Identities = 222/257 (86%), Positives = 236/257 (91%), Gaps = 4/257 (1%) Query: 1 MALAKRIIPCLDVTAGRVVKGVNFLELRDAGDPVEIARRYDEQGADELTFLDITASSDGR 60 MALAKRIIPCLDVTAGRVVKGVNF+ELRDAGDPVEIARRYD+QGADELTFLDITA+SD R Sbjct: 1 MALAKRIIPCLDVTAGRVVKGVNFVELRDAGDPVEIARRYDDQGADELTFLDITATSDQR 60 Query: 61 DLILDIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVGINTSAVTNPQLVADAASK 120 DLIL IIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADK+ +N+SAV NPQLV DA K Sbjct: 61 DLILPIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKISMNSSAVANPQLVKDATDK 120 Query: 121 YGSQCIVVAIDAKR-AGDG---KWEVYTHGGRKATGLDAVEWARKMAQLGAGEILLTSMD 176 YGSQCIVVAIDAKR + DG +WEV+THGGRKATGL+AVEWARKMA+LGAGEILLTSMD Sbjct: 121 YGSQCIVVAIDAKRVSADGEPPRWEVFTHGGRKATGLEAVEWARKMAELGAGEILLTSMD 180 Query: 177 RDGTKSGFDLDLTRAVSEAVSIPVIASGGVGGLQDLADGITKGKADAVLAASIFHYGQHT 236 RDGTKSGFDL LTRAVS+AV IPVIASGGVG LQ LADGI G ADAVLAASIFHYG+HT Sbjct: 181 RDGTKSGFDLALTRAVSDAVPIPVIASGGVGNLQHLADGIKSGHADAVLAASIFHYGEHT 240 Query: 237 VQEAKRFMADQNISMRL 253 V EAKRFMADQ IS+RL Sbjct: 241 VGEAKRFMADQGISVRL 257