BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0088.p (166 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8ISW6.1 D8ISW6_HERSS Phosphoribosyl-AMP cyclohydrolase protein ... 341 3e-92 A4G9I5.1 HIS3_HERAR Phosphoribosyl-AMP cyclohydrolase EC=3.5.4.19 233 6e-60 A6T375.1 HIS3_JANMA Phosphoribosyl-AMP cyclohydrolase EC=3.5.4.19 232 1e-59 F1W3Z4.1 F1W3Z4_9BURK Phosphoribosyl-AMP cyclohydrolase 231 3e-59 B3R793.1 HIS3_CUPTR Phosphoribosyl-AMP cyclohydrolase EC=3.5.4.19 223 5e-57 Q1LIB3.1 HIS3_RALME Phosphoribosyl-AMP cyclohydrolase EC=3.5.4.19 223 6e-57 Q0K694.1 HIS3_CUPNH Phosphoribosyl-AMP cyclohydrolase EC=3.5.4.19 221 3e-56 Q46WL9.1 HIS3_CUPPJ Phosphoribosyl-AMP cyclohydrolase EC=3.5.4.19 221 3e-56 D8NX90.1 D8NX90_RALSO Phosphoribosyl-AMP cyclohydrolase (PRA-CH)... 221 3e-56 B5SJD4.1 B5SJD4_RALSO Phosphoribosyl-amp cyclohydrolase (Pra-ch)... 221 3e-56 >D8ISW6.1 D8ISW6_HERSS Phosphoribosyl-AMP cyclohydrolase protein EC=3.5.4.19 Length = 166 Score = 341 bits (874), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 166/166 (100%), Positives = 166/166 (100%) Query: 1 MSISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVEIGQAVYWSRSRKK 60 MSISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVEIGQAVYWSRSRKK Sbjct: 1 MSISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVEIGQAVYWSRSRKK 60 Query: 61 LWHKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGSADSGEWV 120 LWHKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGSADSGEWV Sbjct: 61 LWHKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGSADSGEWV 120 Query: 121 TVEPVLKDLQPGAGGGPAATAAEPEAKPKRVRKSIPKPVDSDKTPS 166 TVEPVLKDLQPGAGGGPAATAAEPEAKPKRVRKSIPKPVDSDKTPS Sbjct: 121 TVEPVLKDLQPGAGGGPAATAAEPEAKPKRVRKSIPKPVDSDKTPS 166 >A4G9I5.1 HIS3_HERAR Phosphoribosyl-AMP cyclohydrolase EC=3.5.4.19 Length = 134 Score = 233 bits (594), Expect = 6e-60, Method: Compositional matrix adjust. Identities = 109/128 (85%), Positives = 118/128 (92%) Query: 1 MSISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVEIGQAVYWSRSRKK 60 MS +AKWLNKVKWDE GLVPVIAQEVGSNDVLMFAWMNR+ALA+T+E G+A+YWSRSRKK Sbjct: 1 MSSNAKWLNKVKWDEHGLVPVIAQEVGSNDVLMFAWMNRDALAKTIESGEAIYWSRSRKK 60 Query: 61 LWHKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGSADSGEWV 120 LWHKGEESGH QKVHE+RLDCDEDVVLLKVEQV IACHTGRHSCFFQKFEG A G+W Sbjct: 61 LWHKGEESGHTQKVHEVRLDCDEDVVLLKVEQVGAIACHTGRHSCFFQKFEGDAKEGDWE 120 Query: 121 TVEPVLKD 128 TVEPVLK+ Sbjct: 121 TVEPVLKN 128 >A6T375.1 HIS3_JANMA Phosphoribosyl-AMP cyclohydrolase EC=3.5.4.19 Length = 134 Score = 232 bits (592), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 108/128 (84%), Positives = 118/128 (92%) Query: 1 MSISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVEIGQAVYWSRSRKK 60 MS +AKWLNKVKWDE GLVPVIAQEVG+NDVLMFAWMNR+ALA+T+E G+A+YWSRSRKK Sbjct: 1 MSSNAKWLNKVKWDEHGLVPVIAQEVGTNDVLMFAWMNRDALAKTIETGEAIYWSRSRKK 60 Query: 61 LWHKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGSADSGEWV 120 LWHKGEESGH QKVHE+RLDCDEDVVLLKVEQV IACHTGRHSCFFQKFEG A G+W Sbjct: 61 LWHKGEESGHTQKVHEVRLDCDEDVVLLKVEQVGKIACHTGRHSCFFQKFEGGAKDGDWE 120 Query: 121 TVEPVLKD 128 TVEPVLK+ Sbjct: 121 TVEPVLKN 128 >F1W3Z4.1 F1W3Z4_9BURK Phosphoribosyl-AMP cyclohydrolase Length = 134 Score = 231 bits (589), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 108/128 (84%), Positives = 115/128 (89%) Query: 1 MSISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVEIGQAVYWSRSRKK 60 MSI AKWLNKVKWDE GLVPVIAQE+GSNDVLMFAWMNR+AL RTVE G+AVYWSRSRKK Sbjct: 1 MSIKAKWLNKVKWDEYGLVPVIAQELGSNDVLMFAWMNRDALERTVESGEAVYWSRSRKK 60 Query: 61 LWHKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGSADSGEWV 120 LWHKGEESGH QKVH+IRLDCDEDVVLLKVEQ IACHTGRHSCFFQKFEG+ GEWV Sbjct: 61 LWHKGEESGHTQKVHDIRLDCDEDVVLLKVEQTGNIACHTGRHSCFFQKFEGTVGDGEWV 120 Query: 121 TVEPVLKD 128 + +PVL D Sbjct: 121 SADPVLVD 128 >B3R793.1 HIS3_CUPTR Phosphoribosyl-AMP cyclohydrolase EC=3.5.4.19 Length = 134 Score = 223 bits (569), Expect = 5e-57, Method: Compositional matrix adjust. Identities = 103/126 (81%), Positives = 115/126 (91%) Query: 3 ISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVEIGQAVYWSRSRKKLW 62 ++ KWLNKVKWD+ GLVPVI QE GSNDVLMFA+MNR+AL RTVE+G+AV+WSRSRK+LW Sbjct: 1 MAKKWLNKVKWDDNGLVPVIVQEAGSNDVLMFAFMNRDALLRTVELGEAVFWSRSRKRLW 60 Query: 63 HKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGSADSGEWVTV 122 HKGEESGH QKVHEIRLDCDEDVVLLKV QV IACHTGRHSCFFQKF+G AD+G+W TV Sbjct: 61 HKGEESGHVQKVHEIRLDCDEDVVLLKVTQVDSIACHTGRHSCFFQKFDGDADTGDWQTV 120 Query: 123 EPVLKD 128 EPVLKD Sbjct: 121 EPVLKD 126 >Q1LIB3.1 HIS3_RALME Phosphoribosyl-AMP cyclohydrolase EC=3.5.4.19 Length = 135 Score = 223 bits (568), Expect = 6e-57, Method: Compositional matrix adjust. Identities = 103/126 (81%), Positives = 115/126 (91%) Query: 3 ISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVEIGQAVYWSRSRKKLW 62 ++ KWLNKVKWD+ GLVPVI QEVGSNDVLMFA+MNR+AL RTVE+G+AV+WSRSRK+LW Sbjct: 1 MAKKWLNKVKWDDNGLVPVIVQEVGSNDVLMFAFMNRDALQRTVELGEAVFWSRSRKRLW 60 Query: 63 HKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGSADSGEWVTV 122 HKGEESGH QKVHEIRLDCDEDVVLLKV Q+ IACHTGRHSCFFQKFEG +SG+W TV Sbjct: 61 HKGEESGHVQKVHEIRLDCDEDVVLLKVTQIDSIACHTGRHSCFFQKFEGDVESGDWQTV 120 Query: 123 EPVLKD 128 EPVLKD Sbjct: 121 EPVLKD 126 >Q0K694.1 HIS3_CUPNH Phosphoribosyl-AMP cyclohydrolase EC=3.5.4.19 Length = 134 Score = 221 bits (563), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 102/126 (80%), Positives = 114/126 (90%) Query: 3 ISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVEIGQAVYWSRSRKKLW 62 ++ KWLNKVKWD+ GLVPVI QEVGSNDVLMFA+MNR+AL RTVE+G+AV+WSRSRK+LW Sbjct: 1 MAKKWLNKVKWDDNGLVPVIVQEVGSNDVLMFAFMNRDALQRTVELGEAVFWSRSRKRLW 60 Query: 63 HKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGSADSGEWVTV 122 HKGEESGH QKVHEIRLDCDEDVVLLKV Q+ IACHTGRHSCFFQKFEG + G+W TV Sbjct: 61 HKGEESGHVQKVHEIRLDCDEDVVLLKVTQIDNIACHTGRHSCFFQKFEGDVEVGDWQTV 120 Query: 123 EPVLKD 128 EPVLKD Sbjct: 121 EPVLKD 126 >Q46WL9.1 HIS3_CUPPJ Phosphoribosyl-AMP cyclohydrolase EC=3.5.4.19 Length = 135 Score = 221 bits (562), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 101/126 (80%), Positives = 115/126 (91%) Query: 3 ISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVEIGQAVYWSRSRKKLW 62 ++ KWLNKVKWD+ GLVPVI QEVG+NDVLMFA+MNR+AL +T E+G+AV+WSRSRK+LW Sbjct: 1 MAKKWLNKVKWDDNGLVPVIVQEVGTNDVLMFAFMNRDALQKTAELGEAVFWSRSRKRLW 60 Query: 63 HKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGSADSGEWVTV 122 HKGEESGH QKVHE+RLDCDEDVVLLKV QV IACHTGRHSCFFQKFEG A+SG+W TV Sbjct: 61 HKGEESGHVQKVHEMRLDCDEDVVLLKVTQVDNIACHTGRHSCFFQKFEGDAESGDWQTV 120 Query: 123 EPVLKD 128 EPVLKD Sbjct: 121 EPVLKD 126 >D8NX90.1 D8NX90_RALSO Phosphoribosyl-AMP cyclohydrolase (PRA-CH) EC=3.5.4.19 Length = 141 Score = 221 bits (562), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 103/141 (73%), Positives = 118/141 (83%) Query: 3 ISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVEIGQAVYWSRSRKKLW 62 +S KWLNKVKWD+ GLVPV+ QE GSNDVLMFA+MNREAL +TVE G+AV+WSRSRK+LW Sbjct: 1 MSRKWLNKVKWDDHGLVPVVVQEQGSNDVLMFAFMNREALQKTVETGEAVFWSRSRKRLW 60 Query: 63 HKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGSADSGEWVTV 122 HKGEESGH QKVHEIRLDCDEDVVLL+V Q+ GIACHTGRH+CFFQKFEG+A+ G+W TV Sbjct: 61 HKGEESGHIQKVHEIRLDCDEDVVLLRVTQIGGIACHTGRHACFFQKFEGTAEDGDWHTV 120 Query: 123 EPVLKDLQPGAGGGPAATAAE 143 EPVLK G P + E Sbjct: 121 EPVLKSPDEIYSGKPGHSHHE 141 >B5SJD4.1 B5SJD4_RALSO Phosphoribosyl-amp cyclohydrolase (Pra-ch) protein EC=3.5.4.19 Length = 141 Score = 221 bits (562), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 103/141 (73%), Positives = 118/141 (83%) Query: 3 ISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVEIGQAVYWSRSRKKLW 62 +S KWLNKVKWD+ GLVPVI QE GSNDVLMFA+MNREAL +TVE G+AV+WSRSRK+LW Sbjct: 1 MSKKWLNKVKWDDHGLVPVIVQEQGSNDVLMFAFMNREALQKTVETGEAVFWSRSRKRLW 60 Query: 63 HKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGSADSGEWVTV 122 HKGEESGH QKVHE+RLDCDEDVVLL+V Q+ GIACHTGRH+CFFQKFEG+A+ G+W TV Sbjct: 61 HKGEESGHIQKVHEVRLDCDEDVVLLRVTQIGGIACHTGRHACFFQKFEGTAEDGDWHTV 120 Query: 123 EPVLKDLQPGAGGGPAATAAE 143 EPVLK G P + E Sbjct: 121 EPVLKSPDEIYAGKPGHSHHE 141