BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0019.p (255 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8ISN2.1 D8ISN2_HERSS Short-chain alcohol dehydrogenase protein ... 521 e-146 A8HSE3.1 A8HSE3_AZOC5 Short-chain dehydrogenase 356 1e-96 A8TNL0.1 A8TNL0_9PROT Short-chain dehydrogenase/reductase SDR 355 2e-96 B8IB67.1 B8IB67_METNO Short-chain dehydrogenase/reductase SDR 352 4e-95 Q212H9.1 Q212H9_RHOPB Short-chain dehydrogenase/reductase SDR 346 1e-93 Q07PA1.1 Q07PA1_RHOP5 Short-chain dehydrogenase/reductase SDR 343 1e-92 F2LA22.1 F2LA22_BURGA Short-chain dehydrogenase/reductase SDR 342 3e-92 A7IGZ0.1 A7IGZ0_XANP2 Short-chain dehydrogenase/reductase SDR 342 3e-92 A9ILJ9.1 A9ILJ9_BORPD Putative oxidoreductase 340 2e-91 C5AG38.1 C5AG38_BURGB Short-chain dehydrogenase/reductase SDR 338 4e-91 >D8ISN2.1 D8ISN2_HERSS Short-chain alcohol dehydrogenase protein EC=1.-.-.- Length = 255 Score = 521 bits (1341), Expect = e-146, Method: Compositional matrix adjust. Identities = 253/255 (99%), Positives = 254/255 (99%) Query: 1 MAAPQAPKRIALVTGAGSGIGRQITLALLREGYGVALAGRRQDALEETVRLAGEDGPNAL 60 MAAPQAPKRIALVTGAGSGIGRQITLALLREGYGVALAGRRQDALEETVRLAGEDGPNAL Sbjct: 1 MAAPQAPKRIALVTGAGSGIGRQITLALLREGYGVALAGRRQDALEETVRLAGEDGPNAL 60 Query: 61 VVAADVTDPASVKQLFAKTRERFGRLDMLFNNAGIFVPPVSLEELSVEQWKAAVDINLTG 120 VVAADVTDPASVKQLFAKTRERFGRLDMLFNNAGIF PPVSLEELSVEQWKAAVDINLTG Sbjct: 61 VVAADVTDPASVKQLFAKTRERFGRLDMLFNNAGIFAPPVSLEELSVEQWKAAVDINLTG 120 Query: 121 VFLCTQEAFRIMKDQSPRGGRIINNGSISAHAPRPFSASYTATKHAITGLTKATSLDGRA 180 VFLC+QEAFRIMKDQSPRGGRIINNGSISAHAPRPFSASYTATKHAITGLTKATSLDGRA Sbjct: 121 VFLCSQEAFRIMKDQSPRGGRIINNGSISAHAPRPFSASYTATKHAITGLTKATSLDGRA 180 Query: 181 YDIACGQIDIGNASTDMTTLMKKGTLQADGSTKVEPTMDAEHVARAILYMDSLPLEANVQ 240 YDIACGQIDIGNASTDMTTLMKKGTLQADGSTKVEPTMDAEHVARAILYMDSLPLEANVQ Sbjct: 181 YDIACGQIDIGNASTDMTTLMKKGTLQADGSTKVEPTMDAEHVARAILYMDSLPLEANVQ 240 Query: 241 FMTVMATKMPYIGRG 255 FMTVMATKMPYIGRG Sbjct: 241 FMTVMATKMPYIGRG 255 >A8HSE3.1 A8HSE3_AZOC5 Short-chain dehydrogenase Length = 247 Score = 356 bits (914), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 171/248 (68%), Positives = 199/248 (80%), Gaps = 3/248 (1%) Query: 8 KRIALVTGAGSGIGRQITLALLREGYGVALAGRRQDALEETVRLAGEDGPNALVVAADVT 67 +++ALVTGAGSG+G+ + LAL GY VALAGRR DAL+ +A E G AL V DVT Sbjct: 3 RKVALVTGAGSGVGKAVALALAEAGYSVALAGRRADALDA---VAKEIGGEALAVPTDVT 59 Query: 68 DPASVKQLFAKTRERFGRLDMLFNNAGIFVPPVSLEELSVEQWKAAVDINLTGVFLCTQE 127 + V LFA+ RERFGRLD+LFNNAG P + LE+L+V +WK VD NLTG FLCTQE Sbjct: 60 NADEVAALFAQVRERFGRLDLLFNNAGTGAPAIPLEDLTVAEWKKVVDTNLTGPFLCTQE 119 Query: 128 AFRIMKDQSPRGGRIINNGSISAHAPRPFSASYTATKHAITGLTKATSLDGRAYDIACGQ 187 AFRIMKDQ PRGGRIINNGS+S+ APRPFSA YTATKHAITGLT++TSLDGRAYDIACGQ Sbjct: 120 AFRIMKDQDPRGGRIINNGSVSSEAPRPFSAPYTATKHAITGLTRSTSLDGRAYDIACGQ 179 Query: 188 IDIGNASTDMTTLMKKGTLQADGSTKVEPTMDAEHVARAILYMDSLPLEANVQFMTVMAT 247 IDIGNA T+M MK G LQADG+ + EP MD +HVA A++YM SLPLEANVQF+TVMAT Sbjct: 180 IDIGNADTEMAQRMKTGVLQADGTMRAEPVMDVKHVADAVVYMASLPLEANVQFITVMAT 239 Query: 248 KMPYIGRG 255 KMP++GRG Sbjct: 240 KMPFVGRG 247 >A8TNL0.1 A8TNL0_9PROT Short-chain dehydrogenase/reductase SDR Length = 250 Score = 355 bits (912), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 168/247 (68%), Positives = 199/247 (80%) Query: 9 RIALVTGAGSGIGRQITLALLREGYGVALAGRRQDALEETVRLAGEDGPNALVVAADVTD 68 ++A+VTGAGSGIGR +ALL+ G+ V LAGRR+DAL+ET+ AG+ G N L V DV D Sbjct: 4 KVAIVTGAGSGIGRASAIALLKAGWSVGLAGRREDALKETLVKAGDVGKNGLAVPTDVAD 63 Query: 69 PASVKQLFAKTRERFGRLDMLFNNAGIFVPPVSLEELSVEQWKAAVDINLTGVFLCTQEA 128 SVK LF T+ +FGR+DM+FNNAG+ P + LEEL+VEQWKA VD+NLTG FLC EA Sbjct: 64 AVSVKALFDATKAKFGRVDMVFNNAGMNAPGIPLEELTVEQWKAVVDVNLTGSFLCLAEA 123 Query: 129 FRIMKDQSPRGGRIINNGSISAHAPRPFSASYTATKHAITGLTKATSLDGRAYDIACGQI 188 FR+MKDQSPRGGRIINNGSISAHAPRP S+ YTATKHAITGLTK+ SLDGR YDIA Q+ Sbjct: 124 FRVMKDQSPRGGRIINNGSISAHAPRPNSSPYTATKHAITGLTKSGSLDGRKYDIAVCQL 183 Query: 189 DIGNASTDMTTLMKKGTLQADGSTKVEPTMDAEHVARAILYMDSLPLEANVQFMTVMATK 248 DIGNA T+M M KG +QA+G VEP MD +HVA AI++M SLP+EANVQFMTVMATK Sbjct: 184 DIGNAETEMAARMAKGVMQANGEIAVEPLMDVQHVANAIVHMASLPIEANVQFMTVMATK 243 Query: 249 MPYIGRG 255 MP++GRG Sbjct: 244 MPFVGRG 250 >B8IB67.1 B8IB67_METNO Short-chain dehydrogenase/reductase SDR Length = 253 Score = 352 bits (902), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 172/249 (69%), Positives = 193/249 (77%) Query: 7 PKRIALVTGAGSGIGRQITLALLREGYGVALAGRRQDALEETVRLAGEDGPNALVVAADV 66 P+++ALVTGAGSG+GR + L L GY V L+GRR + L G AL DV Sbjct: 5 PQKVALVTGAGSGVGRAVALGLAGAGYDVVLSGRRLEPLAAVRAEVEAKGRRALAHPTDV 64 Query: 67 TDPASVKQLFAKTRERFGRLDMLFNNAGIFVPPVSLEELSVEQWKAAVDINLTGVFLCTQ 126 D ASV LFA E FGRLD+LFNNAGIF PP+ L+EL V WKAAVD NLTG FLCTQ Sbjct: 65 GDEASVAALFAAVAETFGRLDLLFNNAGIFAPPIPLDELPVSAWKAAVDTNLTGAFLCTQ 124 Query: 127 EAFRIMKDQSPRGGRIINNGSISAHAPRPFSASYTATKHAITGLTKATSLDGRAYDIACG 186 AFR+MK Q+PRGGRIINNGSISAHAPRP SA YTATKHAITGLT++TSLDGRA+DIACG Sbjct: 125 GAFRLMKAQTPRGGRIINNGSISAHAPRPNSAPYTATKHAITGLTRSTSLDGRAFDIACG 184 Query: 187 QIDIGNASTDMTTLMKKGTLQADGSTKVEPTMDAEHVARAILYMDSLPLEANVQFMTVMA 246 QIDIGNA+T+MT M+ G QADGS KVEP MD HVA A++YM SLPL+ANVQFMTVMA Sbjct: 185 QIDIGNAATEMTARMQTGVSQADGSVKVEPVMDVRHVADAVVYMASLPLDANVQFMTVMA 244 Query: 247 TKMPYIGRG 255 TKMPYIGRG Sbjct: 245 TKMPYIGRG 253 >Q212H9.1 Q212H9_RHOPB Short-chain dehydrogenase/reductase SDR Length = 256 Score = 346 bits (888), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 169/248 (68%), Positives = 197/248 (79%), Gaps = 1/248 (0%) Query: 8 KRIALVTGAGSGIGRQITLALLREGYGVALAGRRQDALEETVRLAGEDGPNALVVAADVT 67 RIALVTGAGSG+GR LALLR G+ V LAGRR D L ET AGE +LVV AD+T Sbjct: 10 NRIALVTGAGSGVGRATALALLRAGFCVVLAGRRADKLNETAT-AGEAFGKSLVVPADMT 68 Query: 68 DPASVKQLFAKTRERFGRLDMLFNNAGIFVPPVSLEELSVEQWKAAVDINLTGVFLCTQE 127 DP S+ LF T E FGRLD+LFNNAGI PP+ LE++++ QW+A VD NLT FLCTQ Sbjct: 69 DPDSIASLFGTTMEAFGRLDLLFNNAGIGTPPLPLEDVALAQWQAVVDTNLTAPFLCTQH 128 Query: 128 AFRIMKDQSPRGGRIINNGSISAHAPRPFSASYTATKHAITGLTKATSLDGRAYDIACGQ 187 AFRIMK+QSPRGGRIINNGSISAHAPRPFSA+YTATKHAI+GLTKAT+LDGR YDIACGQ Sbjct: 129 AFRIMKEQSPRGGRIINNGSISAHAPRPFSAAYTATKHAISGLTKATALDGRGYDIACGQ 188 Query: 188 IDIGNASTDMTTLMKKGTLQADGSTKVEPTMDAEHVARAILYMDSLPLEANVQFMTVMAT 247 IDIGNA+T+MT M G LQ +GS EP MD +++A A++YM + L+ANV FMTVMAT Sbjct: 189 IDIGNAATEMTERMTGGILQPNGSLMAEPRMDVDNIAEAVVYMATRSLDANVLFMTVMAT 248 Query: 248 KMPYIGRG 255 KMP++GRG Sbjct: 249 KMPFVGRG 256 >Q07PA1.1 Q07PA1_RHOP5 Short-chain dehydrogenase/reductase SDR Length = 252 Score = 343 bits (880), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 168/251 (66%), Positives = 198/251 (78%), Gaps = 1/251 (0%) Query: 5 QAPKRIALVTGAGSGIGRQITLALLREGYGVALAGRRQDALEETVRLAGEDGPNALVVAA 64 A +IA+VTGAGSG+GR LALL+ G+ V L GRR D L ET AGE +LVV A Sbjct: 3 NATNKIAMVTGAGSGVGRASALALLKAGFSVVLTGRRADKLNETAT-AGEAFGKSLVVPA 61 Query: 65 DVTDPASVKQLFAKTRERFGRLDMLFNNAGIFVPPVSLEELSVEQWKAAVDINLTGVFLC 124 D+TDPAS+ LF +T E FGRLD+LFNNAGI PP+ E++SVEQW+A V NLT FLC Sbjct: 62 DMTDPASIAALFERTVEAFGRLDLLFNNAGIGAPPLPFEDVSVEQWQAVVATNLTAPFLC 121 Query: 125 TQEAFRIMKDQSPRGGRIINNGSISAHAPRPFSASYTATKHAITGLTKATSLDGRAYDIA 184 TQ AFRIMK Q+PRGGRIINNGSISAHAPRPFSA+YT+TKHAITGLTK+T+LDGRAYDIA Sbjct: 122 TQHAFRIMKVQNPRGGRIINNGSISAHAPRPFSAAYTSTKHAITGLTKSTALDGRAYDIA 181 Query: 185 CGQIDIGNASTDMTTLMKKGTLQADGSTKVEPTMDAEHVARAILYMDSLPLEANVQFMTV 244 CGQIDIGNA+T+MT M G LQ G T VEP M+ ++VA A++YM + L+ANV FMTV Sbjct: 182 CGQIDIGNAATEMTERMAAGVLQPTGETLVEPRMNVDNVADAVVYMATRTLDANVLFMTV 241 Query: 245 MATKMPYIGRG 255 MATKMP++GRG Sbjct: 242 MATKMPFVGRG 252 >F2LA22.1 F2LA22_BURGA Short-chain dehydrogenase/reductase SDR Length = 249 Score = 342 bits (877), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 165/247 (66%), Positives = 196/247 (79%), Gaps = 1/247 (0%) Query: 9 RIALVTGAGSGIGRQITLALLREGYGVALAGRRQDALEETVRLAGEDGPNALVVAADVTD 68 ++ALVTGA SGIGR + L LL+ GY VALA R+ DALE+ +G G AL ++ DV D Sbjct: 4 KVALVTGASSGIGRSVALGLLQAGYRVALAARKLDALEQVAAESGA-GERALPISCDVGD 62 Query: 69 PASVKQLFAKTRERFGRLDMLFNNAGIFVPPVSLEELSVEQWKAAVDINLTGVFLCTQEA 128 A+V++LF R+GRLD+LFNNAG+F P SLE+L+V QWK AVDINLTG FLC Q A Sbjct: 63 EAAVQRLFDTIESRWGRLDLLFNNAGVFTPQCSLEDLAVAQWKQAVDINLTGAFLCLQGA 122 Query: 129 FRIMKDQSPRGGRIINNGSISAHAPRPFSASYTATKHAITGLTKATSLDGRAYDIACGQI 188 FR+MK Q P+GGRIINNGSISAHAPRP + +YTATKHAITGLTKA SLDGRAY IACGQI Sbjct: 123 FRLMKRQQPQGGRIINNGSISAHAPRPQAVAYTATKHAITGLTKAASLDGRAYGIACGQI 182 Query: 189 DIGNASTDMTTLMKKGTLQADGSTKVEPTMDAEHVARAILYMDSLPLEANVQFMTVMATK 248 DIGN +DM+ LM +GTLQADGS KVEP M ++V RA+LYMDSLPL+ANV MTVMA+ Sbjct: 183 DIGNVVSDMSELMAQGTLQADGSMKVEPRMSMDNVVRAVLYMDSLPLDANVLSMTVMASH 242 Query: 249 MPYIGRG 255 MP++GRG Sbjct: 243 MPFVGRG 249 >A7IGZ0.1 A7IGZ0_XANP2 Short-chain dehydrogenase/reductase SDR Length = 250 Score = 342 bits (877), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 172/248 (69%), Positives = 196/248 (79%), Gaps = 3/248 (1%) Query: 8 KRIALVTGAGSGIGRQITLALLREGYGVALAGRRQDALEETVRLAGEDGPNALVVAADVT 67 K+IA+VTGAGSG+GR + +AL GYGVALAGRR DAL+ET A E G +AL V DVT Sbjct: 6 KKIAIVTGAGSGVGRAVAVALAGAGYGVALAGRRLDALQET---AAEIGDDALCVPTDVT 62 Query: 68 DPASVKQLFAKTRERFGRLDMLFNNAGIFVPPVSLEELSVEQWKAAVDINLTGVFLCTQE 127 DP SV+ LF T E+FGR+D+LFNNAG P + +E+L+ QWK VD NLTG FLCTQE Sbjct: 63 DPDSVRALFTATVEKFGRVDVLFNNAGTGAPAIPMEDLTFAQWKQVVDTNLTGPFLCTQE 122 Query: 128 AFRIMKDQSPRGGRIINNGSISAHAPRPFSASYTATKHAITGLTKATSLDGRAYDIACGQ 187 AFR+MK Q PRGGRIINNGSISA +PRP+SA YTATKHAITGLTK+TSLDGR +DIACGQ Sbjct: 123 AFRVMKAQEPRGGRIINNGSISATSPRPYSAPYTATKHAITGLTKSTSLDGRVHDIACGQ 182 Query: 188 IDIGNASTDMTTLMKKGTLQADGSTKVEPTMDAEHVARAILYMDSLPLEANVQFMTVMAT 247 IDIGNA T M MK G QAD S KVEP MD HVA A++YM SLPL+ANVQFMT+MAT Sbjct: 183 IDIGNADTPMAQKMKAGVPQADLSIKVEPVMDVAHVASAVVYMASLPLDANVQFMTIMAT 242 Query: 248 KMPYIGRG 255 KMP IGRG Sbjct: 243 KMPLIGRG 250 >A9ILJ9.1 A9ILJ9_BORPD Putative oxidoreductase Length = 256 Score = 340 bits (871), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 161/251 (64%), Positives = 197/251 (78%) Query: 5 QAPKRIALVTGAGSGIGRQITLALLREGYGVALAGRRQDALEETVRLAGEDGPNALVVAA 64 QA ++ALVTGAG+GIGR + L L +GY V LAGRR+D LE+T AGEDG ALVV Sbjct: 6 QAGAKVALVTGAGTGIGRAVALEFLAQGYRVVLAGRRRDMLEQTRTAAGEDGARALVVPT 65 Query: 65 DVTDPASVKQLFAKTRERFGRLDMLFNNAGIFVPPVSLEELSVEQWKAAVDINLTGVFLC 124 DV+D +V++LF +T+ +GR+D+LFNNAG P V +E+L VE W+ VD+NLTG+FLC Sbjct: 66 DVSDEQAVRELFDETQRAYGRVDVLFNNAGRNAPAVPIEDLPVETWREVVDVNLTGMFLC 125 Query: 125 TQEAFRIMKDQSPRGGRIINNGSISAHAPRPFSASYTATKHAITGLTKATSLDGRAYDIA 184 Q A R+MK Q P GGRIINNGSISAHAPRPFS +YTATKHA+TGLTK+ SLD R+Y IA Sbjct: 126 AQAAIRLMKAQQPGGGRIINNGSISAHAPRPFSIAYTATKHAVTGLTKSISLDCRSYGIA 185 Query: 185 CGQIDIGNASTDMTTLMKKGTLQADGSTKVEPTMDAEHVARAILYMDSLPLEANVQFMTV 244 CGQIDIGNA+TDMT M G LQADG+ +VEP MD HVA A++ M +LPL+ANVQFMT+ Sbjct: 186 CGQIDIGNAATDMTQRMAAGILQADGTKRVEPRMDVAHVAHAVVSMANLPLDANVQFMTI 245 Query: 245 MATKMPYIGRG 255 MAT MP++GRG Sbjct: 246 MATNMPFVGRG 256 >C5AG38.1 C5AG38_BURGB Short-chain dehydrogenase/reductase SDR Length = 249 Score = 338 bits (868), Expect = 4e-91, Method: Compositional matrix adjust. Identities = 162/247 (65%), Positives = 192/247 (77%), Gaps = 1/247 (0%) Query: 9 RIALVTGAGSGIGRQITLALLREGYGVALAGRRQDALEETVRLAGEDGPNALVVAADVTD 68 ++ALVTGA SGIGR + L LL+ GY V LA R+ +AL + +G AL V DV D Sbjct: 4 KVALVTGASSGIGRSVALGLLQAGYHVVLAARKVEALRQAAEESGAP-ERALAVGCDVGD 62 Query: 69 PASVKQLFAKTRERFGRLDMLFNNAGIFVPPVSLEELSVEQWKAAVDINLTGVFLCTQEA 128 PA+V+ LF + +GRLD+LFNNAG+F P SLEE+ VE WK AVD+NLTG FLCTQ A Sbjct: 63 PAAVQDLFERIDAHWGRLDLLFNNAGVFTPQCSLEEMPVEHWKQAVDVNLTGAFLCTQGA 122 Query: 129 FRIMKDQSPRGGRIINNGSISAHAPRPFSASYTATKHAITGLTKATSLDGRAYDIACGQI 188 FR+MK Q P GGRIINNGSISAHAPRP +A+YTATKHAITGLTKA SLDGR Y+IACGQI Sbjct: 123 FRLMKKQQPGGGRIINNGSISAHAPRPQAAAYTATKHAITGLTKAASLDGRRYNIACGQI 182 Query: 189 DIGNASTDMTTLMKKGTLQADGSTKVEPTMDAEHVARAILYMDSLPLEANVQFMTVMATK 248 DIGN +DM++ M GTLQADGS KVEP M ++V RA+LYMDSLPL+ANV FMTVMA+ Sbjct: 183 DIGNVVSDMSSQMAHGTLQADGSLKVEPRMSMDNVVRAVLYMDSLPLDANVLFMTVMASH 242 Query: 249 MPYIGRG 255 MP++GRG Sbjct: 243 MPFVGRG 249