BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0114.p (230 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IWG3.1 D8IWG3_HERSS Two component heavy metal response transcr... 462 e-128 A1WES7.1 A1WES7_VEREI Two component heavy metal response transcr... 417 e-115 E6UX87.1 E6UX87_VARPD Two component heavy metal response transcr... 386 e-105 A6V861.1 A6V861_PSEA7 Probable two-component response regulator 345 2e-93 Q4K6K4.1 Q4K6K4_PSEF5 DNA-binding heavy metal response regulator 345 2e-93 F2K593.1 F2K593_PSEBR Putative two-component response regulator 343 1e-92 C3KDE6.1 C3KDE6_PSEFS Tw-component system, response regulator 343 1e-92 E2XLV0.1 E2XLV0_PSEFL Two component heavy metal response transcr... 342 2e-92 Q9I3R0.1 Q9I3R0_PSEAE Probable two-component response regulator 342 2e-92 Q02JS1.1 Q02JS1_PSEAB Putative two-component response regulator 342 2e-92 >D8IWG3.1 D8IWG3_HERSS Two component heavy metal response transcription regulator protein Length = 230 Score = 462 bits (1190), Expect = e-128, Method: Compositional matrix adjust. Identities = 229/230 (99%), Positives = 230/230 (100%) Query: 1 MKILIVEDEQKMSEYLCKGLTEQGCAVDLAANGVDGQHLAIEHDYDVIVLDVMLPGLDGF 60 MKILIVEDEQKMSEYLCKGLTEQGCAVDLAANGVDGQHLAIEHDYDVIVLDVMLPGLDGF Sbjct: 1 MKILIVEDEQKMSEYLCKGLTEQGCAVDLAANGVDGQHLAIEHDYDVIVLDVMLPGLDGF 60 Query: 61 SVLRALRKVKETPVIMLTARDSVEDRIKGLHDGADDYLIKPFSFLELLARLQALTRRGRA 120 SVLRALRKVKETPVIMLTARDSVEDRIKGLHDGADDYLIKPFSFLELLARLQALTRRGRA Sbjct: 61 SVLRALRKVKETPVIMLTARDSVEDRIKGLHDGADDYLIKPFSFLELLARLQALTRRGRA 120 Query: 121 QEPAQLRIGDLQIDLLSRKAFRGGLRIDLTAKEFALLAVMARRQGEILSKTAIAELVWDM 180 QEPAQLRIGDLQIDLLSRKAFRGGLRIDLTAKEFALLAVMARRQGEILSKTAIAELVWDM Sbjct: 121 QEPAQLRIGDLQIDLLSRKAFRGGLRIDLTAKEFALLAVMARRQGEILSKTAIAELVWDM 180 Query: 181 NFDSNTNVVEVAIKRLRAKIDAPFEQKLLHTVRGMGYVLEPRATADNSDD 230 NFDSNTNVVEVAIKRLRAKIDAPFEQKLLHTVRGMGYVLEPRATAD+SDD Sbjct: 181 NFDSNTNVVEVAIKRLRAKIDAPFEQKLLHTVRGMGYVLEPRATADSSDD 230 >A1WES7.1 A1WES7_VEREI Two component heavy metal response transcriptional regulator, winged helix family Length = 231 Score = 417 bits (1071), Expect = e-115, Method: Compositional matrix adjust. Identities = 205/229 (89%), Positives = 215/229 (93%) Query: 1 MKILIVEDEQKMSEYLCKGLTEQGCAVDLAANGVDGQHLAIEHDYDVIVLDVMLPGLDGF 60 MKILIVEDE KM+EYL KGL+EQGC VDLAANG+DGQHLAI HDYDVIVLD MLPGLDGF Sbjct: 1 MKILIVEDEHKMAEYLRKGLSEQGCTVDLAANGIDGQHLAIWHDYDVIVLDAMLPGLDGF 60 Query: 61 SVLRALRKVKETPVIMLTARDSVEDRIKGLHDGADDYLIKPFSFLELLARLQALTRRGRA 120 SVLR+LR +K+TPVIMLTARD VEDRIKGLHDGADDYLIKPFSFLELLARLQALTRRGRA Sbjct: 61 SVLRSLRILKQTPVIMLTARDRVEDRIKGLHDGADDYLIKPFSFLELLARLQALTRRGRA 120 Query: 121 QEPAQLRIGDLQIDLLSRKAFRGGLRIDLTAKEFALLAVMARRQGEILSKTAIAELVWDM 180 QEPAQLRIGDLQIDLLSRKA R RIDLTAKEFALLA+MARRQGEILSKTAIAELVWDM Sbjct: 121 QEPAQLRIGDLQIDLLSRKALRNNTRIDLTAKEFALLAIMARRQGEILSKTAIAELVWDM 180 Query: 181 NFDSNTNVVEVAIKRLRAKIDAPFEQKLLHTVRGMGYVLEPRATADNSD 229 NFDSNTNVVEVAIKRLRAKIDAPF QKLLHT+RGMGYVLEPRATA + + Sbjct: 181 NFDSNTNVVEVAIKRLRAKIDAPFSQKLLHTIRGMGYVLEPRATAHDGE 229 >E6UX87.1 E6UX87_VARPD Two component heavy metal response transcriptional regulator, winged helix family Length = 235 Score = 386 bits (992), Expect = e-105, Method: Compositional matrix adjust. Identities = 189/224 (84%), Positives = 203/224 (90%) Query: 1 MKILIVEDEQKMSEYLCKGLTEQGCAVDLAANGVDGQHLAIEHDYDVIVLDVMLPGLDGF 60 MKILIVEDE + ++YL KGLTEQGC VD A NG+DGQHLA+ HDYDVIVLDVMLPG DGF Sbjct: 1 MKILIVEDELRTADYLSKGLTEQGCTVDAAHNGIDGQHLALTHDYDVIVLDVMLPGQDGF 60 Query: 61 SVLRALRKVKETPVIMLTARDSVEDRIKGLHDGADDYLIKPFSFLELLARLQALTRRGRA 120 +VLRALR VK+TPVIMLTARD VEDRIKGLH+GADDYL+KPFSFLELLARLQAL RRGR Sbjct: 61 AVLRALRAVKQTPVIMLTARDRVEDRIKGLHEGADDYLVKPFSFLELLARLQALNRRGRK 120 Query: 121 QEPAQLRIGDLQIDLLSRKAFRGGLRIDLTAKEFALLAVMARRQGEILSKTAIAELVWDM 180 QEP QLRI +LQIDLL+RKAFRG RIDLTAKEFALLAV+ARRQGEILSKTAIAELVWDM Sbjct: 121 QEPVQLRIANLQIDLLARKAFRGATRIDLTAKEFALLAVLARRQGEILSKTAIAELVWDM 180 Query: 181 NFDSNTNVVEVAIKRLRAKIDAPFEQKLLHTVRGMGYVLEPRAT 224 NFDSNTNVVEVAIKRLR KIDAPF KLLHT+RGMGYV+E R T Sbjct: 181 NFDSNTNVVEVAIKRLRDKIDAPFSPKLLHTIRGMGYVMELRDT 224 >A6V861.1 A6V861_PSEA7 Probable two-component response regulator Length = 229 Score = 345 bits (886), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 168/227 (74%), Positives = 200/227 (88%), Gaps = 1/227 (0%) Query: 1 MKILIVEDEQKMSEYLCKGLTEQGCAVDLAANGVDGQHLAIEHDYDVIVLDVMLPGLDGF 60 M++LIVEDE K ++YL +GLTEQG VDLA NG+DG+HLA+ +YDVIVLDVMLPG+DG+ Sbjct: 1 MRVLIVEDEAKTADYLNRGLTEQGFTVDLADNGIDGRHLALNGEYDVIVLDVMLPGIDGY 60 Query: 61 SVLRALRKVKETPVIMLTARDSVEDRIKGLHDGADDYLIKPFSFLELLARLQALTRRGRA 120 VLRALR+ ++TPVIMLTAR+ VEDR++GL +GADDYLIKPFSFLEL+ARLQALTRRG Sbjct: 61 GVLRALREQRQTPVIMLTARERVEDRVRGLREGADDYLIKPFSFLELVARLQALTRRGGN 120 Query: 121 QEPA-QLRIGDLQIDLLSRKAFRGGLRIDLTAKEFALLAVMARRQGEILSKTAIAELVWD 179 E A Q+R+ DL IDLLSRK FRGG R++LTAKE+ALL V+A+R GEILSKTAIAELVWD Sbjct: 121 HESASQMRVADLSIDLLSRKVFRGGSRLELTAKEYALLCVLAQRSGEILSKTAIAELVWD 180 Query: 180 MNFDSNTNVVEVAIKRLRAKIDAPFEQKLLHTVRGMGYVLEPRATAD 226 +NFD++TNVVEVAIKRLRAK+D PFE KLLHT+RGMGYVLE RA A+ Sbjct: 181 INFDTDTNVVEVAIKRLRAKLDGPFENKLLHTIRGMGYVLENRALAE 227 >Q4K6K4.1 Q4K6K4_PSEF5 DNA-binding heavy metal response regulator Length = 225 Score = 345 bits (886), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 169/223 (75%), Positives = 194/223 (86%) Query: 1 MKILIVEDEQKMSEYLCKGLTEQGCAVDLAANGVDGQHLAIEHDYDVIVLDVMLPGLDGF 60 M++LI+EDE+K ++YL +GLTEQG VDLA +GV+G H+A+E DY VIVLDVMLPGLDGF Sbjct: 1 MRVLIIEDEEKTADYLHRGLTEQGYTVDLARDGVEGLHMALEGDYAVIVLDVMLPGLDGF 60 Query: 61 SVLRALRKVKETPVIMLTARDSVEDRIKGLHDGADDYLIKPFSFLELLARLQALTRRGRA 120 VLRALR K+TPVIMLTAR+ VEDRIKGL DGADDYL KPFSFLEL+ARLQALTRR Sbjct: 61 GVLRALRARKQTPVIMLTARERVEDRIKGLRDGADDYLGKPFSFLELVARLQALTRRSGG 120 Query: 121 QEPAQLRIGDLQIDLLSRKAFRGGLRIDLTAKEFALLAVMARRQGEILSKTAIAELVWDM 180 EP Q+ I DL IDL+SRKA R G R+DLTAKEF+LL+V+ARRQGEILSKTAIAE+VWD+ Sbjct: 121 HEPVQISIADLWIDLISRKASRAGSRLDLTAKEFSLLSVLARRQGEILSKTAIAEMVWDI 180 Query: 181 NFDSNTNVVEVAIKRLRAKIDAPFEQKLLHTVRGMGYVLEPRA 223 NFDS+ NVVEVAIKRLRAK+D PFEQKLLHT+RGMGYVLE R Sbjct: 181 NFDSDANVVEVAIKRLRAKLDGPFEQKLLHTIRGMGYVLESRG 223 >F2K593.1 F2K593_PSEBR Putative two-component response regulator Length = 227 Score = 343 bits (880), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 167/223 (74%), Positives = 195/223 (87%) Query: 1 MKILIVEDEQKMSEYLCKGLTEQGCAVDLAANGVDGQHLAIEHDYDVIVLDVMLPGLDGF 60 M++LI+EDE+K ++YL +GL+EQG VD+A +G++G HLA+E DY VIVLDVMLPGLDGF Sbjct: 1 MRVLIIEDEEKTADYLHRGLSEQGYTVDVAPDGIEGLHLALETDYAVIVLDVMLPGLDGF 60 Query: 61 SVLRALRKVKETPVIMLTARDSVEDRIKGLHDGADDYLIKPFSFLELLARLQALTRRGRA 120 VLRALR K+TPVIMLTAR+ VEDRIKGL DGADDYL KPFSFLEL+ARLQALTRR Sbjct: 61 GVLRALRARKQTPVIMLTARERVEDRIKGLRDGADDYLGKPFSFLELVARLQALTRRSGG 120 Query: 121 QEPAQLRIGDLQIDLLSRKAFRGGLRIDLTAKEFALLAVMARRQGEILSKTAIAELVWDM 180 EP Q+ I DL IDL+SRKA R G R+DLTAKEF+LL+V+ARRQGEILSKTAIAE+VWD+ Sbjct: 121 HEPVQVSIADLWIDLISRKATRAGQRLDLTAKEFSLLSVLARRQGEILSKTAIAEMVWDI 180 Query: 181 NFDSNTNVVEVAIKRLRAKIDAPFEQKLLHTVRGMGYVLEPRA 223 NFDS+ NVVEVAIKRLRAK+D PFEQKLLHT+RGMGYVLE R+ Sbjct: 181 NFDSDANVVEVAIKRLRAKLDGPFEQKLLHTIRGMGYVLESRS 223 >C3KDE6.1 C3KDE6_PSEFS Tw-component system, response regulator Length = 230 Score = 343 bits (879), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 166/222 (74%), Positives = 195/222 (87%) Query: 1 MKILIVEDEQKMSEYLCKGLTEQGCAVDLAANGVDGQHLAIEHDYDVIVLDVMLPGLDGF 60 M++LI+EDE+K ++YL +GLTEQG VD+A GV+G HLA+E+DY VIVLDVMLPGLDGF Sbjct: 1 MRVLIIEDEEKTADYLHRGLTEQGYTVDVAREGVEGLHLALENDYAVIVLDVMLPGLDGF 60 Query: 61 SVLRALRKVKETPVIMLTARDSVEDRIKGLHDGADDYLIKPFSFLELLARLQALTRRGRA 120 VLRALR K+TPVIMLTAR+ VEDRI+GL +GADDYL KPFSFLEL+ARLQALTRR Sbjct: 61 GVLRALRARKQTPVIMLTARERVEDRIRGLREGADDYLGKPFSFLELVARLQALTRRSGG 120 Query: 121 QEPAQLRIGDLQIDLLSRKAFRGGLRIDLTAKEFALLAVMARRQGEILSKTAIAELVWDM 180 EP Q+ + DL IDL+SRKA R G+R+DLTAKEF+LL+V+ARRQGEILSKTAIAE+VWD+ Sbjct: 121 HEPVQVTVADLWIDLISRKASRNGVRLDLTAKEFSLLSVLARRQGEILSKTAIAEMVWDI 180 Query: 181 NFDSNTNVVEVAIKRLRAKIDAPFEQKLLHTVRGMGYVLEPR 222 NFDS+ NVVEVAIKRLRAK+D PFEQKLLHT+RGMGYVLE R Sbjct: 181 NFDSDANVVEVAIKRLRAKLDGPFEQKLLHTIRGMGYVLESR 222 >E2XLV0.1 E2XLV0_PSEFL Two component heavy metal response transcriptional regulator, winged helix family Length = 225 Score = 342 bits (877), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 167/225 (74%), Positives = 195/225 (86%) Query: 1 MKILIVEDEQKMSEYLCKGLTEQGCAVDLAANGVDGQHLAIEHDYDVIVLDVMLPGLDGF 60 M+ILIVEDE+K ++YL +GLTEQG VD+A GV+G HLA+E+DY VIVLDVMLPGLDGF Sbjct: 1 MRILIVEDEEKTADYLHRGLTEQGYTVDVAREGVEGLHLALENDYAVIVLDVMLPGLDGF 60 Query: 61 SVLRALRKVKETPVIMLTARDSVEDRIKGLHDGADDYLIKPFSFLELLARLQALTRRGRA 120 VLRALR K+TPVIMLTAR+ VEDRI+GL +GADDYL KPFSFLEL+ARLQALTRR Sbjct: 61 GVLRALRARKQTPVIMLTARERVEDRIRGLREGADDYLGKPFSFLELVARLQALTRRSGG 120 Query: 121 QEPAQLRIGDLQIDLLSRKAFRGGLRIDLTAKEFALLAVMARRQGEILSKTAIAELVWDM 180 EP Q+ + DL IDL+SRKA R G+R+DLTAKEF+LL+V+ARRQGEILSKTAIAE+VWD+ Sbjct: 121 HEPVQVTVADLWIDLISRKASRNGVRLDLTAKEFSLLSVLARRQGEILSKTAIAEMVWDI 180 Query: 181 NFDSNTNVVEVAIKRLRAKIDAPFEQKLLHTVRGMGYVLEPRATA 225 NFDS+ NVVEVAIKRLRAK+D PFE KLLHT+RGMGYVLE R+ Sbjct: 181 NFDSDANVVEVAIKRLRAKLDGPFEHKLLHTIRGMGYVLENRSVG 225 >Q9I3R0.1 Q9I3R0_PSEAE Probable two-component response regulator Length = 229 Score = 342 bits (877), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 166/229 (72%), Positives = 200/229 (87%), Gaps = 1/229 (0%) Query: 1 MKILIVEDEQKMSEYLCKGLTEQGCAVDLAANGVDGQHLAIEHDYDVIVLDVMLPGLDGF 60 M++LIVEDE K ++YL +GL+EQG VDLA NG+DG+HLA+ +YDVIVLDVMLPG+DG+ Sbjct: 1 MRVLIVEDEAKTADYLNRGLSEQGFTVDLADNGIDGRHLALHGEYDVIVLDVMLPGVDGY 60 Query: 61 SVLRALRKVKETPVIMLTARDSVEDRIKGLHDGADDYLIKPFSFLELLARLQALTRRGRA 120 VLRALR+ ++TPVIMLTAR+ VEDR++GL +GADDYLIKPFSFLEL+ARLQALTRRG Sbjct: 61 GVLRALRERRQTPVIMLTARERVEDRVRGLREGADDYLIKPFSFLELVARLQALTRRGGN 120 Query: 121 QEP-AQLRIGDLQIDLLSRKAFRGGLRIDLTAKEFALLAVMARRQGEILSKTAIAELVWD 179 E +Q+RI DL IDLLSRK FRG R++LTAKE+ALL V+A+R GEILSKTAIAELVWD Sbjct: 121 HESHSQMRIADLSIDLLSRKVFRGNTRLELTAKEYALLCVLAQRSGEILSKTAIAELVWD 180 Query: 180 MNFDSNTNVVEVAIKRLRAKIDAPFEQKLLHTVRGMGYVLEPRATADNS 228 +NFD++TNVVEVAIKRLRAK+D PFE KLLHT+RGMGYVLE RA A++ Sbjct: 181 INFDTDTNVVEVAIKRLRAKLDGPFENKLLHTIRGMGYVLENRALAESG 229 >Q02JS1.1 Q02JS1_PSEAB Putative two-component response regulator Length = 229 Score = 342 bits (877), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 166/229 (72%), Positives = 200/229 (87%), Gaps = 1/229 (0%) Query: 1 MKILIVEDEQKMSEYLCKGLTEQGCAVDLAANGVDGQHLAIEHDYDVIVLDVMLPGLDGF 60 M++LIVEDE K ++YL +GL+EQG VDLA NG+DG+HLA+ +YDVIVLDVMLPG+DG+ Sbjct: 1 MRVLIVEDEAKTADYLNRGLSEQGFTVDLADNGIDGRHLALHGEYDVIVLDVMLPGVDGY 60 Query: 61 SVLRALRKVKETPVIMLTARDSVEDRIKGLHDGADDYLIKPFSFLELLARLQALTRRGRA 120 VLRALR+ ++TPVIMLTAR+ VEDR++GL +GADDYLIKPFSFLEL+ARLQALTRRG Sbjct: 61 GVLRALRERRQTPVIMLTARERVEDRVRGLREGADDYLIKPFSFLELVARLQALTRRGGN 120 Query: 121 QEP-AQLRIGDLQIDLLSRKAFRGGLRIDLTAKEFALLAVMARRQGEILSKTAIAELVWD 179 E +Q+RI DL IDLLSRK FRG R++LTAKE+ALL V+A+R GEILSKTAIAELVWD Sbjct: 121 HESHSQMRIADLSIDLLSRKVFRGNTRLELTAKEYALLCVLAQRSGEILSKTAIAELVWD 180 Query: 180 MNFDSNTNVVEVAIKRLRAKIDAPFEQKLLHTVRGMGYVLEPRATADNS 228 +NFD++TNVVEVAIKRLRAK+D PFE KLLHT+RGMGYVLE RA A++ Sbjct: 181 INFDTDTNVVEVAIKRLRAKLDGPFENKLLHTIRGMGYVLENRALAESG 229