BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0029.0321.p (264 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IRF4.1 D8IRF4_HERSS Triosephosphate isomerase EC=5.3.1.1 487 e-136 A6SY03.1 TPIS_JANMA Triosephosphate isomerase EC=5.3.1.1 363 2e-98 A4G646.1 TPIS_HERAR Triosephosphate isomerase EC=5.3.1.1 354 7e-96 Q0KCT2.1 TPIS_CUPNH Triosephosphate isomerase EC=5.3.1.1 324 6e-87 B3R3W5.1 TPIS_CUPTR Triosephosphate isomerase EC=5.3.1.1 323 1e-86 Q1LPW5.1 Q1LPW5_RALME Triosephosphate isomerase 1 EC=5.3.1.1 320 1e-85 F1VU55.1 F1VU55_9BURK Triosephosphate isomerase 319 2e-85 C6BJQ1.1 C6BJQ1_RALP1 Triosephosphate isomerase EC=5.3.1.1 318 5e-85 E2T114.1 E2T114_9RALS Triosephosphate isomerase EC=5.3.1.1 318 5e-85 B2U7R3.1 B2U7R3_RALPJ Triosephosphate isomerase EC=5.3.1.1 317 1e-84 >D8IRF4.1 D8IRF4_HERSS Triosephosphate isomerase EC=5.3.1.1 Length = 249 Score = 487 bits (1254), Expect = e-136, Method: Compositional matrix adjust. Identities = 248/249 (99%), Positives = 249/249 (100%) Query: 16 MRRKLVAGNWKMNGSLAANAALVAGIKEGLAAQACDVAVCVPAPYLAQVQALVAGSPVGL 75 MRRKLVAGNWKMNGSLAANAALVAGIKEGLAAQACDVAVCVPAPYLAQVQALVAGSPVGL Sbjct: 1 MRRKLVAGNWKMNGSLAANAALVAGIKEGLAAQACDVAVCVPAPYLAQVQALVAGSPVGL 60 Query: 76 GAQDMSAHASGAYTGDVSASMLQEFGVQYVILGHSERRAYHGESDAAVAAKTVAALKAGL 135 GAQDMSAHASGAYTG+VSASMLQEFGVQYVILGHSERRAYHGESDAAVAAKTVAALKAGL Sbjct: 61 GAQDMSAHASGAYTGEVSASMLQEFGVQYVILGHSERRAYHGESDAAVAAKTVAALKAGL 120 Query: 136 VPLVCVGETLEQREAGQTNAVVGGQLDVVLAALSAEEAARIVVAYEPVWAIGTGKTATPE 195 VPLVCVGETLEQREAGQTNAVVGGQLDVVLAALSAEEAARIVVAYEPVWAIGTGKTATPE Sbjct: 121 VPLVCVGETLEQREAGQTNAVVGGQLDVVLAALSAEEAARIVVAYEPVWAIGTGKTATPE 180 Query: 196 MAQEVHAMLRARLGAKSAEAAAKVCILYGGSMKPDNAQQLLAMGDIDGGLIGGAALKAAD 255 MAQEVHAMLRARLGAKSAEAAAKVCILYGGSMKPDNAQQLLAMGDIDGGLIGGAALKAAD Sbjct: 181 MAQEVHAMLRARLGAKSAEAAAKVCILYGGSMKPDNAQQLLAMGDIDGGLIGGAALKAAD 240 Query: 256 FLAIINAAA 264 FLAIINAAA Sbjct: 241 FLAIINAAA 249 >A6SY03.1 TPIS_JANMA Triosephosphate isomerase EC=5.3.1.1 Length = 248 Score = 363 bits (931), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 178/248 (71%), Positives = 210/248 (84%) Query: 16 MRRKLVAGNWKMNGSLAANAALVAGIKEGLAAQACDVAVCVPAPYLAQVQALVAGSPVGL 75 MRRKLVAGNWKMNGSLAAN L+ IK GL DVAVCVP+PY AQ Q L+ G+ + L Sbjct: 1 MRRKLVAGNWKMNGSLAANTLLLTEIKSGLGNATSDVAVCVPSPYFAQCQGLLNGAAIAL 60 Query: 76 GAQDMSAHASGAYTGDVSASMLQEFGVQYVILGHSERRAYHGESDAAVAAKTVAALKAGL 135 GAQD+S+H +GAYTG+VS SMLQEF +YVI+GHSERRAY E++ +A KTV AL AGL Sbjct: 61 GAQDVSSHEAGAYTGEVSTSMLQEFDCRYVIVGHSERRAYFAETNELIAQKTVRALNAGL 120 Query: 136 VPLVCVGETLEQREAGQTNAVVGGQLDVVLAALSAEEAARIVVAYEPVWAIGTGKTATPE 195 P+VCVGETL+QREAGQT++VV QL+VVLA+++A + A+IVVAYEPVWAIGTGKTATP Sbjct: 121 TPIVCVGETLDQREAGQTDSVVAEQLNVVLASIAASDLAKIVVAYEPVWAIGTGKTATPA 180 Query: 196 MAQEVHAMLRARLGAKSAEAAAKVCILYGGSMKPDNAQQLLAMGDIDGGLIGGAALKAAD 255 MAQEVHAMLR +L AK+AEAA +V ILYGGSMKP+NA++LLAM DIDGGLIGGAALKAAD Sbjct: 181 MAQEVHAMLRKQLQAKNAEAAMQVRILYGGSMKPENAKELLAMSDIDGGLIGGAALKAAD 240 Query: 256 FLAIINAA 263 FLAI++AA Sbjct: 241 FLAIVHAA 248 >A4G646.1 TPIS_HERAR Triosephosphate isomerase EC=5.3.1.1 Length = 248 Score = 354 bits (909), Expect = 7e-96, Method: Compositional matrix adjust. Identities = 183/248 (73%), Positives = 211/248 (85%) Query: 16 MRRKLVAGNWKMNGSLAANAALVAGIKEGLAAQACDVAVCVPAPYLAQVQALVAGSPVGL 75 MRRKLVAGNWKMNGSLAANA L+A IK ACDVAVCVPAPYLAQ +L++ S + L Sbjct: 1 MRRKLVAGNWKMNGSLAANALLLAEIKAEFGNPACDVAVCVPAPYLAQCLSLLSDSTIAL 60 Query: 76 GAQDMSAHASGAYTGDVSASMLQEFGVQYVILGHSERRAYHGESDAAVAAKTVAALKAGL 135 GAQD+S+H SGAYTG+VS +ML EF +YVI+GHSERRAY GE++ VA KTV AL AGL Sbjct: 61 GAQDVSSHDSGAYTGEVSTAMLLEFACRYVIVGHSERRAYFGETNELVAQKTVRALSAGL 120 Query: 136 VPLVCVGETLEQREAGQTNAVVGGQLDVVLAALSAEEAARIVVAYEPVWAIGTGKTATPE 195 +P+VCVGETLEQREAGQT+ VVG Q+D VL++++ + A+IVVAYEPVWAIGTGKTATPE Sbjct: 121 MPIVCVGETLEQREAGQTDEVVGRQIDAVLSSIAENDLAKIVVAYEPVWAIGTGKTATPE 180 Query: 196 MAQEVHAMLRARLGAKSAEAAAKVCILYGGSMKPDNAQQLLAMGDIDGGLIGGAALKAAD 255 MAQEVH MLR RL AK+A+AA +V ILYGGSMKPDNA++LLAM DIDGGLIGGAALKAAD Sbjct: 181 MAQEVHVMLRRRLHAKNAQAATEVRILYGGSMKPDNAKELLAMPDIDGGLIGGAALKAAD 240 Query: 256 FLAIINAA 263 FLAII AA Sbjct: 241 FLAIIRAA 248 >Q0KCT2.1 TPIS_CUPNH Triosephosphate isomerase EC=5.3.1.1 Length = 245 Score = 324 bits (831), Expect = 6e-87, Method: Compositional matrix adjust. Identities = 167/247 (67%), Positives = 200/247 (80%), Gaps = 2/247 (0%) Query: 16 MRRKLVAGNWKMNGSLAANAALVAGIKEGLAAQACDVAVCVPAPYLAQVQALVAGSPVGL 75 MR+KLV GNWKM+GSLAANAAL+ GIK G AA+A +AVC P PYLAQ QAL+ GS V Sbjct: 1 MRQKLVIGNWKMHGSLAANAALLEGIKAG-AAKAT-LAVCAPFPYLAQCQALLNGSQVAW 58 Query: 76 GAQDMSAHASGAYTGDVSASMLQEFGVQYVILGHSERRAYHGESDAAVAAKTVAALKAGL 135 GAQD+SA A GA+TG+VSASM+ EFG YV++GHSERR YHGE+D VAAK + AL+ G+ Sbjct: 59 GAQDVSAEARGAFTGEVSASMVGEFGCTYVLVGHSERRTYHGETDQTVAAKALRALEFGI 118 Query: 136 VPLVCVGETLEQREAGQTNAVVGGQLDVVLAALSAEEAARIVVAYEPVWAIGTGKTATPE 195 VP+VCVGETL QREAG+T AVVG QL VL AL+ E+ +R+V+AYEPVWAIGTGKTAT E Sbjct: 119 VPVVCVGETLAQREAGETEAVVGRQLQAVLDALTVEQLSRVVLAYEPVWAIGTGKTATSE 178 Query: 196 MAQEVHAMLRARLGAKSAEAAAKVCILYGGSMKPDNAQQLLAMGDIDGGLIGGAALKAAD 255 AQ VHA LR ++ A+ A A ++ ILYGGS+KPDNA +L +M DIDGGLIGGA+LK+AD Sbjct: 179 QAQAVHAFLRGQVAARDAGVAERMAILYGGSVKPDNAAELFSMTDIDGGLIGGASLKSAD 238 Query: 256 FLAIINA 262 FLAI NA Sbjct: 239 FLAIGNA 245 >B3R3W5.1 TPIS_CUPTR Triosephosphate isomerase EC=5.3.1.1 Length = 247 Score = 323 bits (829), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 163/247 (65%), Positives = 195/247 (78%) Query: 16 MRRKLVAGNWKMNGSLAANAALVAGIKEGLAAQACDVAVCVPAPYLAQVQALVAGSPVGL 75 MR+KLV GNWKM+GSLAANAAL+ GI+ G +AVC P PYLAQ QAL+ GS V Sbjct: 1 MRQKLVIGNWKMHGSLAANAALLEGIQAGAGVARATLAVCAPFPYLAQCQALLNGSKVAW 60 Query: 76 GAQDMSAHASGAYTGDVSASMLQEFGVQYVILGHSERRAYHGESDAAVAAKTVAALKAGL 135 GAQD+SA A GA+TG+V+ASML EFG YV++GHSERR YHGE+D AVAAK + AL+ G+ Sbjct: 61 GAQDVSAEARGAFTGEVAASMLGEFGCTYVLVGHSERRTYHGETDQAVAAKALRALEFGI 120 Query: 136 VPLVCVGETLEQREAGQTNAVVGGQLDVVLAALSAEEAARIVVAYEPVWAIGTGKTATPE 195 VP+VCVGETL QREAG+T AVVG QL VL AL+ E+ R+V+AYEPVWAIGTGKTAT E Sbjct: 121 VPVVCVGETLAQREAGETEAVVGRQLQAVLEALTVEQLGRVVLAYEPVWAIGTGKTATSE 180 Query: 196 MAQEVHAMLRARLGAKSAEAAAKVCILYGGSMKPDNAQQLLAMGDIDGGLIGGAALKAAD 255 AQ VHA LR ++ A+ A A ++ ILYGGS+KPDNA +L +M DIDGGLIGGA+LK+ D Sbjct: 181 QAQAVHAFLRGQVAARDAGVAGRMAILYGGSVKPDNAAELFSMTDIDGGLIGGASLKSED 240 Query: 256 FLAIINA 262 FLAI NA Sbjct: 241 FLAIGNA 247 >Q1LPW5.1 Q1LPW5_RALME Triosephosphate isomerase 1 EC=5.3.1.1 Length = 245 Score = 320 bits (821), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 167/247 (67%), Positives = 195/247 (78%), Gaps = 2/247 (0%) Query: 16 MRRKLVAGNWKMNGSLAANAALVAGIKEGLAAQACDVAVCVPAPYLAQVQALVAGSPVGL 75 MR+KLV GNWKM+GSLAANAAL+ GIK A +AVC P PYLAQ Q L++GS V Sbjct: 1 MRQKLVIGNWKMHGSLAANAALLEGIKA--APARAKLAVCAPFPYLAQCQTLLSGSQVAW 58 Query: 76 GAQDMSAHASGAYTGDVSASMLQEFGVQYVILGHSERRAYHGESDAAVAAKTVAALKAGL 135 GAQD+S+ A GA+TG+V+ASML EFG Y ++GHSERR YHGE+DA VAAK + AL+ + Sbjct: 59 GAQDVSSEARGAFTGEVAASMLGEFGCGYALVGHSERRTYHGETDAVVAAKALRALEFDI 118 Query: 136 VPLVCVGETLEQREAGQTNAVVGGQLDVVLAALSAEEAARIVVAYEPVWAIGTGKTATPE 195 VP+VCVGETL +REAGQT AVVG QL VL ALS E+ RIV+AYEPVWAIGTGKTAT Sbjct: 119 VPVVCVGETLAEREAGQTEAVVGRQLQAVLDALSIEQLGRIVLAYEPVWAIGTGKTATSA 178 Query: 196 MAQEVHAMLRARLGAKSAEAAAKVCILYGGSMKPDNAQQLLAMGDIDGGLIGGAALKAAD 255 AQEVHA LRAR+ AK A AA++ ILYGGS+KPDNA +L +M DIDGGLIGGA+LKA D Sbjct: 179 QAQEVHAALRARVTAKDAGVAARMAILYGGSVKPDNAAELFSMSDIDGGLIGGASLKADD 238 Query: 256 FLAIINA 262 FLAI NA Sbjct: 239 FLAIGNA 245 >F1VU55.1 F1VU55_9BURK Triosephosphate isomerase Length = 252 Score = 319 bits (818), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 166/250 (66%), Positives = 197/250 (78%), Gaps = 1/250 (0%) Query: 16 MRRKLVAGNWKMNGSLAANAALVAGIKEGLA-AQACDVAVCVPAPYLAQVQALVAGSPVG 74 MRRKLVAGNWKMNG+LAAN+AL+ + + A CD+AVCVPAPYLA Q + + + Sbjct: 1 MRRKLVAGNWKMNGNLAANSALLYELVAAIGHAAPCDIAVCVPAPYLALCQQQLTNTAIA 60 Query: 75 LGAQDMSAHASGAYTGDVSASMLQEFGVQYVILGHSERRAYHGESDAAVAAKTVAALKAG 134 G QD+SAH +GAYTG+VSA+ML +F YV++GHSERRA HGE++A V KTV AL+AG Sbjct: 61 WGGQDLSAHEAGAYTGEVSATMLTDFRSHYVVVGHSERRAMHGENNALVGQKTVRALRAG 120 Query: 135 LVPLVCVGETLEQREAGQTNAVVGGQLDVVLAALSAEEAARIVVAYEPVWAIGTGKTATP 194 LVP+VCVGETL +REAG T VVG QL+ VL L + RIVVAYEPVWAIGTGKTATP Sbjct: 121 LVPIVCVGETLSEREAGLTMQVVGDQLNAVLDLLEPADLTRIVVAYEPVWAIGTGKTATP 180 Query: 195 EMAQEVHAMLRARLGAKSAEAAAKVCILYGGSMKPDNAQQLLAMGDIDGGLIGGAALKAA 254 +MAQEVHA LR L A+ A AA +CILYGGSMKPDNA +L+AM DIDGGLIGGAALK+A Sbjct: 181 DMAQEVHAGLRQLLAARDALAAEGICILYGGSMKPDNAHELMAMADIDGGLIGGAALKSA 240 Query: 255 DFLAIINAAA 264 DFLAII A++ Sbjct: 241 DFLAIIAASS 250 >C6BJQ1.1 C6BJQ1_RALP1 Triosephosphate isomerase EC=5.3.1.1 Length = 248 Score = 318 bits (815), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 163/243 (67%), Positives = 191/243 (78%), Gaps = 1/243 (0%) Query: 17 RRKLVAGNWKMNGSLAANAALVAGIKEGLAAQACDVAVCVPAPYLAQVQALVAGSPVGLG 76 R KLV GNWK++GSL+ NAAL+ IK A +AVC P PYLAQ Q+L+AGS V G Sbjct: 4 RPKLVVGNWKLHGSLSTNAALLEQIKAA-GKTAATLAVCAPFPYLAQCQSLLAGSAVAWG 62 Query: 77 AQDMSAHASGAYTGDVSASMLQEFGVQYVILGHSERRAYHGESDAAVAAKTVAALKAGLV 136 AQD+SA A GA+TG+V+ASML EFG YVI+GHSERR+YHGE+DA VAAK + AL+ G+ Sbjct: 63 AQDVSAEARGAFTGEVAASMLSEFGCGYVIVGHSERRSYHGETDAQVAAKALRALEHGIT 122 Query: 137 PLVCVGETLEQREAGQTNAVVGGQLDVVLAALSAEEAARIVVAYEPVWAIGTGKTATPEM 196 P+VCVGETL QREAG+T VVG QLD VL ALS E+ RIVVAYEPVWAIGTGKTA+ E Sbjct: 123 PIVCVGETLAQREAGETEQVVGRQLDAVLEALSVEQLGRIVVAYEPVWAIGTGKTASSEQ 182 Query: 197 AQEVHAMLRARLGAKSAEAAAKVCILYGGSMKPDNAQQLLAMGDIDGGLIGGAALKAADF 256 AQ VHA LRAR+ A+ A A ++ ILYGGS+KPDNA +L AM DIDGGLIGGA+LKA DF Sbjct: 183 AQAVHAFLRARVAARDAGVAQRLAILYGGSVKPDNAGELFAMADIDGGLIGGASLKAEDF 242 Query: 257 LAI 259 LAI Sbjct: 243 LAI 245 >E2T114.1 E2T114_9RALS Triosephosphate isomerase EC=5.3.1.1 Length = 248 Score = 318 bits (815), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 163/243 (67%), Positives = 191/243 (78%), Gaps = 1/243 (0%) Query: 17 RRKLVAGNWKMNGSLAANAALVAGIKEGLAAQACDVAVCVPAPYLAQVQALVAGSPVGLG 76 R KLV GNWK++GSL+ NAAL+ IK A +AVC P PYLAQ Q+L+AGS V G Sbjct: 4 RPKLVVGNWKLHGSLSTNAALLEQIKAA-GKTAATLAVCAPFPYLAQCQSLLAGSAVAWG 62 Query: 77 AQDMSAHASGAYTGDVSASMLQEFGVQYVILGHSERRAYHGESDAAVAAKTVAALKAGLV 136 AQD+SA A GA+TG+V+ASML EFG YVI+GHSERR+YHGE+DA VAAK + AL+ G+ Sbjct: 63 AQDVSAEARGAFTGEVAASMLSEFGCGYVIVGHSERRSYHGETDAQVAAKALRALEHGIT 122 Query: 137 PLVCVGETLEQREAGQTNAVVGGQLDVVLAALSAEEAARIVVAYEPVWAIGTGKTATPEM 196 P+VCVGETL QREAG+T VVG QLD VL ALS E+ RIVVAYEPVWAIGTGKTA+ E Sbjct: 123 PIVCVGETLAQREAGETEQVVGRQLDAVLEALSVEQLGRIVVAYEPVWAIGTGKTASSEQ 182 Query: 197 AQEVHAMLRARLGAKSAEAAAKVCILYGGSMKPDNAQQLLAMGDIDGGLIGGAALKAADF 256 AQ VHA LRAR+ A+ A A ++ ILYGGS+KPDNA +L AM DIDGGLIGGA+LKA DF Sbjct: 183 AQAVHAFLRARVAARDAGVAQRLAILYGGSVKPDNAGELFAMADIDGGLIGGASLKAEDF 242 Query: 257 LAI 259 LAI Sbjct: 243 LAI 245 >B2U7R3.1 B2U7R3_RALPJ Triosephosphate isomerase EC=5.3.1.1 Length = 248 Score = 317 bits (812), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 162/243 (66%), Positives = 189/243 (77%), Gaps = 1/243 (0%) Query: 17 RRKLVAGNWKMNGSLAANAALVAGIKEGLAAQACDVAVCVPAPYLAQVQALVAGSPVGLG 76 R KLV GNWK++GSL+ NAAL+ IK A +AVCVP PYLAQ Q+L+AGS VG G Sbjct: 4 RPKLVVGNWKLHGSLSTNAALLEQIKAAGKTNAT-LAVCVPFPYLAQCQSLLAGSAVGWG 62 Query: 77 AQDMSAHASGAYTGDVSASMLQEFGVQYVILGHSERRAYHGESDAAVAAKTVAALKAGLV 136 AQD+SA GA+TG+V+ASML EFG Y I+GHSERR+YHGE+DA VA K + AL+ G+ Sbjct: 63 AQDVSAETRGAFTGEVAASMLSEFGCGYAIVGHSERRSYHGETDAQVATKALRALEHGIT 122 Query: 137 PLVCVGETLEQREAGQTNAVVGGQLDVVLAALSAEEAARIVVAYEPVWAIGTGKTATPEM 196 P+VCVGETL QREAG+T VV QLD VL ALS E+ RIVVAYEPVWAIGTGKTAT E Sbjct: 123 PIVCVGETLAQREAGETEQVVARQLDAVLEALSVEQLGRIVVAYEPVWAIGTGKTATSEQ 182 Query: 197 AQEVHAMLRARLGAKSAEAAAKVCILYGGSMKPDNAQQLLAMGDIDGGLIGGAALKAADF 256 AQ VHA LRAR+ A+ A A ++ ILYGGS+KPDNA +L AM DIDGGLIGGA+LKA DF Sbjct: 183 AQAVHAFLRARVAARDAGVAQRLSILYGGSVKPDNAGELFAMADIDGGLIGGASLKAEDF 242 Query: 257 LAI 259 LAI Sbjct: 243 LAI 245