BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0029.0052.p (462 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IPY2.1 D8IPY2_HERSS Fumarate hydratase class II (Fumarase) pro... 947 0.0 F1VUM9.1 F1VUM9_9BURK Fumarate hydratase class II 709 0.0 E5UDT2.1 E5UDT2_ALCXX Fumarate hydratase class II 706 0.0 D9SHX5.1 D9SHX5_GALCS Fumarate hydratase, class II 705 0.0 A6T1A6.1 A6T1A6_JANMA Fumarate hydratase, class II EC=4.2.1.2 705 0.0 D4X7W6.1 D4X7W6_9BURK Fumarate hydratase EC=4.2.1.2 704 0.0 E3HHM0.1 E3HHM0_ACHXA Fumarate hydratase, class II EC=4.2.1.2 704 0.0 Q5QCQ9.1 Q5QCQ9_HERAR Putative furamase EC=4.2.1.2 703 0.0 D8NEG9.1 D8NEG9_RALSO Fumarase C (Fumarate hydratase) EC=4.2.1.2 696 0.0 A9I7Z4.1 A9I7Z4_BORPD Fumarate hydratase class II EC=4.2.1.2 696 0.0 >D8IPY2.1 D8IPY2_HERSS Fumarate hydratase class II (Fumarase) protein EC=4.2.1.2 Length = 462 Score = 947 bits (2449), Expect = 0.0, Method: Compositional matrix adjust. Identities = 462/462 (100%), Positives = 462/462 (100%) Query: 1 MNHRMERDTFGLIEVPADRLWGAQTERSLHHFHISTERMPAELIVALAAVKRACASVNRD 60 MNHRMERDTFGLIEVPADRLWGAQTERSLHHFHISTERMPAELIVALAAVKRACASVNRD Sbjct: 1 MNHRMERDTFGLIEVPADRLWGAQTERSLHHFHISTERMPAELIVALAAVKRACASVNRD 60 Query: 61 LGKLDGKKAEAIIAAADEVIAGKHPLEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGV 120 LGKLDGKKAEAIIAAADEVIAGKHPLEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGV Sbjct: 61 LGKLDGKKAEAIIAAADEVIAGKHPLEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGV 120 Query: 121 RGEDRLIHPNDDVNRGQSSNDIFPTAMHVAACMAVATHLIPALHTLRGTLAEKSSQFADI 180 RGEDRLIHPNDDVNRGQSSNDIFPTAMHVAACMAVATHLIPALHTLRGTLAEKSSQFADI Sbjct: 121 RGEDRLIHPNDDVNRGQSSNDIFPTAMHVAACMAVATHLIPALHTLRGTLAEKSSQFADI 180 Query: 181 VKIGRTHLQDATPLTLGQEFSGYVAQLEHAESAVIGTLNAISELAAGGTAVGTGLNAHPE 240 VKIGRTHLQDATPLTLGQEFSGYVAQLEHAESAVIGTLNAISELAAGGTAVGTGLNAHPE Sbjct: 181 VKIGRTHLQDATPLTLGQEFSGYVAQLEHAESAVIGTLNAISELAAGGTAVGTGLNAHPE 240 Query: 241 FGERVAAELAKFFGFPFKTAPNKFAALAGHDALVASHGGLKTLAAALMKIANDVRWLASG 300 FGERVAAELAKFFGFPFKTAPNKFAALAGHDALVASHGGLKTLAAALMKIANDVRWLASG Sbjct: 241 FGERVAAELAKFFGFPFKTAPNKFAALAGHDALVASHGGLKTLAAALMKIANDVRWLASG 300 Query: 301 PRSGLGEITIPENEPGSSIMPGKVNPTQCEAMTMLCAQVFGNDVALNIGGASGNFELNVF 360 PRSGLGEITIPENEPGSSIMPGKVNPTQCEAMTMLCAQVFGNDVALNIGGASGNFELNVF Sbjct: 301 PRSGLGEITIPENEPGSSIMPGKVNPTQCEAMTMLCAQVFGNDVALNIGGASGNFELNVF 360 Query: 361 KPLIIHNFLQSVRLLADGMASFEEHCARGIEANHSRIGELMEKSLMLVTALAPHIGYDKA 420 KPLIIHNFLQSVRLLADGMASFEEHCARGIEANHSRIGELMEKSLMLVTALAPHIGYDKA Sbjct: 361 KPLIIHNFLQSVRLLADGMASFEEHCARGIEANHSRIGELMEKSLMLVTALAPHIGYDKA 420 Query: 421 AKIAKQAHHDGTTLKQAALSLGYVTEEQFAEWIKPEQMTRPG 462 AKIAKQAHHDGTTLKQAALSLGYVTEEQFAEWIKPEQMTRPG Sbjct: 421 AKIAKQAHHDGTTLKQAALSLGYVTEEQFAEWIKPEQMTRPG 462 >F1VUM9.1 F1VUM9_9BURK Fumarate hydratase class II Length = 464 Score = 709 bits (1830), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/458 (75%), Positives = 388/458 (84%) Query: 4 RMERDTFGLIEVPADRLWGAQTERSLHHFHISTERMPAELIVALAAVKRACASVNRDLGK 63 R E D+FG I VPA +LWGAQT+RSL F ISTERMPAELIVALAAVKRACA VN LG+ Sbjct: 5 RTETDSFGPIAVPAAQLWGAQTQRSLEFFRISTERMPAELIVALAAVKRACARVNGALGR 64 Query: 64 LDGKKAEAIIAAADEVIAGKHPLEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGVRGE 123 L K AI+ AADEVIAG+HP EFPL+VWQTGSGTQ+NMNMNEVLANRASELLGG RG Sbjct: 65 LPADKVRAIVQAADEVIAGQHPGEFPLAVWQTGSGTQTNMNMNEVLANRASELLGGPRGA 124 Query: 124 DRLIHPNDDVNRGQSSNDIFPTAMHVAACMAVATHLIPALHTLRGTLAEKSSQFADIVKI 183 +RL+HPND+VN GQSSNDIFPTAMHVAA A+ HLIPAL LR +L KS+ F+DIVKI Sbjct: 125 ERLLHPNDEVNLGQSSNDIFPTAMHVAASGAITQHLIPALQALRQSLQLKSTAFSDIVKI 184 Query: 184 GRTHLQDATPLTLGQEFSGYVAQLEHAESAVIGTLNAISELAAGGTAVGTGLNAHPEFGE 243 GRTHLQDATPLTLGQEFSGYVAQLE AESA+ +L + LAAGGTAVGTGLNA FGE Sbjct: 185 GRTHLQDATPLTLGQEFSGYVAQLEFAESAIASSLAGLQALAAGGTAVGTGLNAPAGFGE 244 Query: 244 RVAAELAKFFGFPFKTAPNKFAALAGHDALVASHGGLKTLAAALMKIANDVRWLASGPRS 303 VAAELA+ G P+ +A NKFAALAGH+ +VA+HG LKTLA ALMKIANDVRWLASGPRS Sbjct: 245 LVAAELARAQGLPYTSAVNKFAALAGHEPMVAAHGALKTLATALMKIANDVRWLASGPRS 304 Query: 304 GLGEITIPENEPGSSIMPGKVNPTQCEAMTMLCAQVFGNDVALNIGGASGNFELNVFKPL 363 GLGEI+IP NEPGSSIMPGKVNPTQCEA+TMLC QVFGNDVA+ +G ASGNFELNVFKPL Sbjct: 305 GLGEISIPANEPGSSIMPGKVNPTQCEALTMLCCQVFGNDVAITVGAASGNFELNVFKPL 364 Query: 364 IIHNFLQSVRLLADGMASFEEHCARGIEANHSRIGELMEKSLMLVTALAPHIGYDKAAKI 423 I H FLQSVRLLADGMASF+ HC +GI N +RI EL+ +SLMLVTAL PHIGYD+AA+I Sbjct: 365 IAHAFLQSVRLLADGMASFDAHCVQGIVPNDARIDELLARSLMLVTALTPHIGYDRAAQI 424 Query: 424 AKQAHHDGTTLKQAALSLGYVTEEQFAEWIKPEQMTRP 461 AK+AH DG++L+QAA++LGYV+ E FA W++P QMT P Sbjct: 425 AKRAHGDGSSLEQAAMALGYVSAEDFARWVQPRQMTTP 462 >E5UDT2.1 E5UDT2_ALCXX Fumarate hydratase class II Length = 463 Score = 706 bits (1821), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/462 (74%), Positives = 390/462 (84%) Query: 1 MNHRMERDTFGLIEVPADRLWGAQTERSLHHFHISTERMPAELIVALAAVKRACASVNRD 60 M R+E+DTFG IEVP D LWGAQT+RSLH F ISTE+MP L++A+A +KRA A VN D Sbjct: 1 MKTRIEKDTFGPIEVPEDHLWGAQTQRSLHFFAISTEKMPEPLVIAMARLKRAAAKVNAD 60 Query: 61 LGKLDGKKAEAIIAAADEVIAGKHPLEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGV 120 LG+LD K A+ II AADEVIAGK P EFPLSVWQTGSGTQSNMNMNEVLANRASELLGGV Sbjct: 61 LGELDPKIADGIIRAADEVIAGKWPNEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGV 120 Query: 121 RGEDRLIHPNDDVNRGQSSNDIFPTAMHVAACMAVATHLIPALHTLRGTLAEKSSQFADI 180 RGE+R +HPND VNRGQSSND FPTAMHVAA + V HL+PAL TLR T A KS++F DI Sbjct: 121 RGEERKVHPNDHVNRGQSSNDTFPTAMHVAAAVQVEHHLLPALKTLRATFAAKSAEFYDI 180 Query: 181 VKIGRTHLQDATPLTLGQEFSGYVAQLEHAESAVIGTLNAISELAAGGTAVGTGLNAHPE 240 VKIGRTHLQDATPLTLGQE SGYVAQL+ AE + TL + +LA GGTAVGTGLNAHP+ Sbjct: 181 VKIGRTHLQDATPLTLGQELSGYVAQLDLAEQQIRATLPGLHQLAIGGTAVGTGLNAHPQ 240 Query: 241 FGERVAAELAKFFGFPFKTAPNKFAALAGHDALVASHGGLKTLAAALMKIANDVRWLASG 300 F +V+AELA F +APNKF ALA H+AL+ +HG LK+LAA LMKIANDVRWL+SG Sbjct: 241 FSAKVSAELAHATETAFVSAPNKFQALASHEALLFAHGALKSLAAGLMKIANDVRWLSSG 300 Query: 301 PRSGLGEITIPENEPGSSIMPGKVNPTQCEAMTMLCAQVFGNDVALNIGGASGNFELNVF 360 PRSGLGEI+IPENEPGSSIMPGKVNPTQCEA+TML AQV GNDVA+NIGGASGNFELNV+ Sbjct: 301 PRSGLGEISIPENEPGSSIMPGKVNPTQCEAITMLAAQVMGNDVAINIGGASGNFELNVY 360 Query: 361 KPLIIHNFLQSVRLLADGMASFEEHCARGIEANHSRIGELMEKSLMLVTALAPHIGYDKA 420 KPL+IHNFLQSVRLL DGMASF++HCA GI+ N RI EL+++SLMLVTAL PHIGYDKA Sbjct: 361 KPLVIHNFLQSVRLLTDGMASFDQHCAAGIQPNRERIAELVDRSLMLVTALNPHIGYDKA 420 Query: 421 AKIAKQAHHDGTTLKQAALSLGYVTEEQFAEWIKPEQMTRPG 462 A+IAK+AH +G +LK++AL+LGYVTE QFAEW+ P MT G Sbjct: 421 AQIAKKAHKEGLSLKESALALGYVTEAQFAEWVVPGSMTNAG 462 >D9SHX5.1 D9SHX5_GALCS Fumarate hydratase, class II Length = 468 Score = 705 bits (1819), Expect = 0.0, Method: Compositional matrix adjust. Identities = 337/458 (73%), Positives = 382/458 (83%) Query: 4 RMERDTFGLIEVPADRLWGAQTERSLHHFHISTERMPAELIVALAAVKRACASVNRDLGK 63 R E D G I VPADRLWGAQT+RSL HFHISTER+P E+I+ALA VKRAC VNRDL Sbjct: 5 RREHDALGEIAVPADRLWGAQTQRSLKHFHISTERIPEEMIMALAEVKRACVLVNRDLAL 64 Query: 64 LDGKKAEAIIAAADEVIAGKHPLEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGVRGE 123 L +KA AI+ A DEV+AG+H EFPLSVWQTGSGTQSNMNMNEVLANRASELLGG RGE Sbjct: 65 LSEEKASAIVRAVDEVLAGRHINEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGTRGE 124 Query: 124 DRLIHPNDDVNRGQSSNDIFPTAMHVAACMAVATHLIPALHTLRGTLAEKSSQFADIVKI 183 R IHPND+VN GQSSNDIFPTAMHVAA ++ L+PAL LR TL K+ F+D++KI Sbjct: 125 ARKIHPNDEVNLGQSSNDIFPTAMHVAAVTGISHQLLPALSVLRTTLKIKADNFSDLLKI 184 Query: 184 GRTHLQDATPLTLGQEFSGYVAQLEHAESAVIGTLNAISELAAGGTAVGTGLNAHPEFGE 243 GRTHLQDATP+TLGQEFSGYVAQ++HA SA++ L+ + LAAGGTA+GTGLN H EFGE Sbjct: 185 GRTHLQDATPMTLGQEFSGYVAQIDHARSAILAALDPLYALAAGGTAIGTGLNTHAEFGE 244 Query: 244 RVAAELAKFFGFPFKTAPNKFAALAGHDALVASHGGLKTLAAALMKIANDVRWLASGPRS 303 RVA+ LA GFPF++A NKF+ALA HDALV +HG LK LA LMKIANDVRWLASGPRS Sbjct: 245 RVASILACRTGFPFRSADNKFSALAAHDALVFAHGALKLLATVLMKIANDVRWLASGPRS 304 Query: 304 GLGEITIPENEPGSSIMPGKVNPTQCEAMTMLCAQVFGNDVALNIGGASGNFELNVFKPL 363 GLGEI+IPENEPGSSIMPGKVNPTQCEA+TM+C Q+FGNDVA+ I GASGNFELNVFKPL Sbjct: 305 GLGEISIPENEPGSSIMPGKVNPTQCEALTMVCCQIFGNDVAITIAGASGNFELNVFKPL 364 Query: 364 IIHNFLQSVRLLADGMASFEEHCARGIEANHSRIGELMEKSLMLVTALAPHIGYDKAAKI 423 I HNF QSVRLLAD +ASFE++CARGIEAN SR+ ELME+SLMLVTAL PHIGYD+AA+I Sbjct: 365 IAHNFSQSVRLLADSIASFEQYCARGIEANRSRLTELMEQSLMLVTALVPHIGYDRAAEI 424 Query: 424 AKQAHHDGTTLKQAALSLGYVTEEQFAEWIKPEQMTRP 461 A AHH G TLK++A++LGYVTEE F WI P M P Sbjct: 425 ANYAHHHGCTLKESAITLGYVTEEAFRSWITPVAMAHP 462 >A6T1A6.1 A6T1A6_JANMA Fumarate hydratase, class II EC=4.2.1.2 Length = 462 Score = 705 bits (1819), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/462 (75%), Positives = 390/462 (84%) Query: 1 MNHRMERDTFGLIEVPADRLWGAQTERSLHHFHISTERMPAELIVALAAVKRACASVNRD 60 M R+ERDTFG IEV + RLWGAQT+RSL HF ISTE+MP ELI+ALA VKRA A VN D Sbjct: 1 MTTRIERDTFGPIEVDSQRLWGAQTQRSLEHFKISTEKMPQELIIALAEVKRAAAIVNLD 60 Query: 61 LGKLDGKKAEAIIAAADEVIAGKHPLEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGV 120 LGKL KA+AI AA+EVI G+HPLEFPL+VWQTGSGTQSNMNMNEVLANRASELLGG Sbjct: 61 LGKLAKDKAQAIAQAAEEVIDGRHPLEFPLAVWQTGSGTQSNMNMNEVLANRASELLGGE 120 Query: 121 RGEDRLIHPNDDVNRGQSSNDIFPTAMHVAACMAVATHLIPALHTLRGTLAEKSSQFADI 180 RGE RL+HPNDDVN GQSSNDIFPTAM+VAA +AV+ L+PA L+ TL K+ +FADI Sbjct: 121 RGEKRLVHPNDDVNLGQSSNDIFPTAMYVAASVAVSKTLLPAATALQATLNGKAEEFADI 180 Query: 181 VKIGRTHLQDATPLTLGQEFSGYVAQLEHAESAVIGTLNAISELAAGGTAVGTGLNAHPE 240 VKIGRTHLQDATPLTLGQEFSGYVAQL + +A+ L + +LA GGTAVGTGLN HPE Sbjct: 181 VKIGRTHLQDATPLTLGQEFSGYVAQLAQSTAAIHALLPPLQDLAVGGTAVGTGLNTHPE 240 Query: 241 FGERVAAELAKFFGFPFKTAPNKFAALAGHDALVASHGGLKTLAAALMKIANDVRWLASG 300 FG RVAAEL + G FK+A NKFAALA HDA+V+ HGGLKTLAA++MKIANDVRWLASG Sbjct: 241 FGVRVAAELTQRTGVTFKSADNKFAALAAHDAMVSVHGGLKTLAASMMKIANDVRWLASG 300 Query: 301 PRSGLGEITIPENEPGSSIMPGKVNPTQCEAMTMLCAQVFGNDVALNIGGASGNFELNVF 360 PRSGLGEI+IPENEPGSSIMPGKVNPTQ EA+TMLC QVFGNDVALN GGASGNFELNVF Sbjct: 301 PRSGLGEISIPENEPGSSIMPGKVNPTQSEAVTMLCCQVFGNDVALNFGGASGNFELNVF 360 Query: 361 KPLIIHNFLQSVRLLADGMASFEEHCARGIEANHSRIGELMEKSLMLVTALAPHIGYDKA 420 KPL+ HNFLQSVRLLADG+ SF+EHCA GI AN RI +LME+SLMLVTALAPHIGYDKA Sbjct: 361 KPLLAHNFLQSVRLLADGIHSFDEHCAHGIVANRDRIADLMERSLMLVTALAPHIGYDKA 420 Query: 421 AKIAKQAHHDGTTLKQAALSLGYVTEEQFAEWIKPEQMTRPG 462 AKIAKQAH G LK+ AL+LGYVT E+F W+KP+ M PG Sbjct: 421 AKIAKQAHQQGANLKETALALGYVTSEEFDLWVKPQDMIHPG 462 >D4X7W6.1 D4X7W6_9BURK Fumarate hydratase EC=4.2.1.2 Length = 464 Score = 704 bits (1817), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/459 (74%), Positives = 388/459 (84%) Query: 1 MNHRMERDTFGLIEVPADRLWGAQTERSLHHFHISTERMPAELIVALAAVKRACASVNRD 60 M R+E+DTFG IEVP D LWGAQT+RSLH F ISTE+MP L+ A+A +KRA A VN + Sbjct: 1 MKTRIEKDTFGPIEVPEDHLWGAQTQRSLHFFAISTEKMPVPLVNAMARLKRAAAKVNAE 60 Query: 61 LGKLDGKKAEAIIAAADEVIAGKHPLEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGV 120 LG+LD K A+ II AADEVIAGK P EFPLSVWQTGSGTQSNMNMNEVLANRASELLGGV Sbjct: 61 LGELDPKIADGIIRAADEVIAGKWPNEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGV 120 Query: 121 RGEDRLIHPNDDVNRGQSSNDIFPTAMHVAACMAVATHLIPALHTLRGTLAEKSSQFADI 180 RGE+R +HPND VNRGQSSND FPTAMHVAA + V HL+P+L LR TLAEKS+ F DI Sbjct: 121 RGEERKVHPNDHVNRGQSSNDTFPTAMHVAAAVEVEHHLLPSLKQLRATLAEKSAAFYDI 180 Query: 181 VKIGRTHLQDATPLTLGQEFSGYVAQLEHAESAVIGTLNAISELAAGGTAVGTGLNAHPE 240 VKIGRTHLQDATPLTLGQE SGYVAQL+ AE + TL + +LA GGTAVGTGLNAHP+ Sbjct: 181 VKIGRTHLQDATPLTLGQELSGYVAQLDLAEQQIRATLPGLHQLAIGGTAVGTGLNAHPQ 240 Query: 241 FGERVAAELAKFFGFPFKTAPNKFAALAGHDALVASHGGLKTLAAALMKIANDVRWLASG 300 F +V+A+LA G F +APNKF ALA H+AL+ +HG LK+LAA LMKIANDVRWL+SG Sbjct: 241 FSAKVSADLAHATGTAFVSAPNKFQALASHEALLFAHGALKSLAAGLMKIANDVRWLSSG 300 Query: 301 PRSGLGEITIPENEPGSSIMPGKVNPTQCEAMTMLCAQVFGNDVALNIGGASGNFELNVF 360 PRSGLGEI+IPENEPGSSIMPGKVNPTQCEA+TML AQV GNDVA+NIGGASGNFELNVF Sbjct: 301 PRSGLGEISIPENEPGSSIMPGKVNPTQCEAITMLAAQVLGNDVAINIGGASGNFELNVF 360 Query: 361 KPLIIHNFLQSVRLLADGMASFEEHCARGIEANHSRIGELMEKSLMLVTALAPHIGYDKA 420 KPL+IHNFLQSVRLL DGMASF HCA GIE NH RI EL+++SLMLVTAL PHIGYDKA Sbjct: 361 KPLVIHNFLQSVRLLTDGMASFNAHCAAGIEPNHERIAELVDRSLMLVTALNPHIGYDKA 420 Query: 421 AKIAKQAHHDGTTLKQAALSLGYVTEEQFAEWIKPEQMT 459 A+IAK+AH +G +LK++AL+LGYVTE QFAEW+ P MT Sbjct: 421 AQIAKKAHKEGLSLKESALALGYVTEAQFAEWVVPGSMT 459 >E3HHM0.1 E3HHM0_ACHXA Fumarate hydratase, class II EC=4.2.1.2 Length = 465 Score = 704 bits (1816), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/459 (74%), Positives = 387/459 (84%) Query: 1 MNHRMERDTFGLIEVPADRLWGAQTERSLHHFHISTERMPAELIVALAAVKRACASVNRD 60 M R+E+DTFG IEVP D LWGAQT+RSLH F ISTE+MP L+ A+A +KRA A VN D Sbjct: 1 MKTRIEKDTFGPIEVPEDHLWGAQTQRSLHFFAISTEKMPVPLVEAMARLKRAAAKVNAD 60 Query: 61 LGKLDGKKAEAIIAAADEVIAGKHPLEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGV 120 LG+LD K A+ I+ AADEVIAGK P EFPLSVWQTGSGTQSNMNMNEVLANRASELLGGV Sbjct: 61 LGELDPKIADGIVRAADEVIAGKWPNEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGV 120 Query: 121 RGEDRLIHPNDDVNRGQSSNDIFPTAMHVAACMAVATHLIPALHTLRGTLAEKSSQFADI 180 RGE+R +HPND VNRGQSSND FPTAMHVAA + V HL+P+L LR TLA KS++F DI Sbjct: 121 RGEERKVHPNDHVNRGQSSNDTFPTAMHVAAAVQVEHHLLPSLKALRATLAAKSAEFYDI 180 Query: 181 VKIGRTHLQDATPLTLGQEFSGYVAQLEHAESAVIGTLNAISELAAGGTAVGTGLNAHPE 240 VKIGRTHLQDATPLTLGQE SGYVAQL+ AE + TL + +LA GGTAVGTGLNAHP+ Sbjct: 181 VKIGRTHLQDATPLTLGQELSGYVAQLDLAEQQIRATLPGLHQLAIGGTAVGTGLNAHPQ 240 Query: 241 FGERVAAELAKFFGFPFKTAPNKFAALAGHDALVASHGGLKTLAAALMKIANDVRWLASG 300 F +V+AELA G F +APNKF LA H+AL+ +HG LK+LAA LMKIANDVRWL+SG Sbjct: 241 FSAKVSAELAHATGTAFVSAPNKFQGLASHEALLFAHGALKSLAAGLMKIANDVRWLSSG 300 Query: 301 PRSGLGEITIPENEPGSSIMPGKVNPTQCEAMTMLCAQVFGNDVALNIGGASGNFELNVF 360 PRSGLGEI+IPENEPGSSIMPGKVNPTQCEA+TML AQV GNDVA+NIGGASGNFELNVF Sbjct: 301 PRSGLGEISIPENEPGSSIMPGKVNPTQCEAITMLAAQVLGNDVAINIGGASGNFELNVF 360 Query: 361 KPLIIHNFLQSVRLLADGMASFEEHCARGIEANHSRIGELMEKSLMLVTALAPHIGYDKA 420 KPL+IHNFLQSVRLL DGMASF EHCA GIE N RI EL+++SLMLVTAL PHIGYDKA Sbjct: 361 KPLVIHNFLQSVRLLTDGMASFNEHCAAGIEPNLERIAELVDRSLMLVTALNPHIGYDKA 420 Query: 421 AKIAKQAHHDGTTLKQAALSLGYVTEEQFAEWIKPEQMT 459 A+IAK+AH +G +LK++AL+LGYVTE QFAEW+ P MT Sbjct: 421 AQIAKKAHKEGLSLKESALALGYVTEAQFAEWVVPASMT 459 >Q5QCQ9.1 Q5QCQ9_HERAR Putative furamase EC=4.2.1.2 Length = 462 Score = 703 bits (1814), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/461 (75%), Positives = 394/461 (85%) Query: 1 MNHRMERDTFGLIEVPADRLWGAQTERSLHHFHISTERMPAELIVALAAVKRACASVNRD 60 M R+ERDTFG I V +RLWGAQT+RSL HF ISTERMP ELIVALA VKRA A N Sbjct: 1 MKTRIERDTFGPIAVNDERLWGAQTQRSLEHFKISTERMPQELIVALAEVKRAAALANLG 60 Query: 61 LGKLDGKKAEAIIAAADEVIAGKHPLEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGV 120 LGKLD KKA+AI++AA+EVIAG+HP EFPL++WQTGSGTQ+NMNMNEVLANRASELLGG Sbjct: 61 LGKLDRKKADAIVSAAEEVIAGQHPHEFPLALWQTGSGTQTNMNMNEVLANRASELLGGE 120 Query: 121 RGEDRLIHPNDDVNRGQSSNDIFPTAMHVAACMAVATHLIPALHTLRGTLAEKSSQFADI 180 RGE RL+HPNDDVN GQSSNDIFPTAM+VAA +++ L+PA+H LR TL K+ +FADI Sbjct: 121 RGEQRLVHPNDDVNLGQSSNDIFPTAMYVAASVSITQKLLPAIHALRVTLQRKAEEFADI 180 Query: 181 VKIGRTHLQDATPLTLGQEFSGYVAQLEHAESAVIGTLNAISELAAGGTAVGTGLNAHPE 240 VKIGRTHLQDATPLTLGQEFSGYVAQL HAE ++ L + ELA GGTAVGTGLN HPE Sbjct: 181 VKIGRTHLQDATPLTLGQEFSGYVAQLHHAELGIVVLLPPLHELAVGGTAVGTGLNTHPE 240 Query: 241 FGERVAAELAKFFGFPFKTAPNKFAALAGHDALVASHGGLKTLAAALMKIANDVRWLASG 300 FG RVAAEL + G FK+A NKFAALA HDALV+ HGGLKTLAA++MKIANDVRWLASG Sbjct: 241 FGTRVAAELTQRSGVHFKSAANKFAALAAHDALVSVHGGLKTLAASMMKIANDVRWLASG 300 Query: 301 PRSGLGEITIPENEPGSSIMPGKVNPTQCEAMTMLCAQVFGNDVALNIGGASGNFELNVF 360 PRSGLGE++IPENEPGSSIMPGKVNPTQ EA+TMLC QVFGNDVALN GGASGNFELNVF Sbjct: 301 PRSGLGELSIPENEPGSSIMPGKVNPTQSEAVTMLCCQVFGNDVALNFGGASGNFELNVF 360 Query: 361 KPLIIHNFLQSVRLLADGMASFEEHCARGIEANHSRIGELMEKSLMLVTALAPHIGYDKA 420 KPL+ HNFLQSVRLL+DG+ F+EHCA+GI AN RI +LM +SLMLVTAL PHIGYDKA Sbjct: 361 KPLMAHNFLQSVRLLSDGIHGFDEHCAQGIAANRERIADLMARSLMLVTALTPHIGYDKA 420 Query: 421 AKIAKQAHHDGTTLKQAALSLGYVTEEQFAEWIKPEQMTRP 461 A+IAKQAHHDGTTLK+ AL+LG+V+ E+F W++P+ M P Sbjct: 421 AQIAKQAHHDGTTLKETALALGFVSSEEFDRWVQPQDMLHP 461 >D8NEG9.1 D8NEG9_RALSO Fumarase C (Fumarate hydratase) EC=4.2.1.2 Length = 463 Score = 696 bits (1797), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/458 (73%), Positives = 383/458 (83%) Query: 1 MNHRMERDTFGLIEVPADRLWGAQTERSLHHFHISTERMPAELIVALAAVKRACASVNRD 60 M R ERDTFG IEVPADRLWGAQT+RSL +F I+ +RMP ELI ALA +KRA A+VN+ Sbjct: 3 MTTRTERDTFGPIEVPADRLWGAQTQRSLQNFDIAGDRMPRELIDALARIKRASATVNQR 62 Query: 61 LGKLDGKKAEAIIAAADEVIAGKHPLEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGV 120 LG L KA A+IAAADEVIAGKHP EFPL VWQTGSGTQSNMNMNEVLANRASELLGG Sbjct: 63 LGLLPADKANAVIAAADEVIAGKHPGEFPLVVWQTGSGTQSNMNMNEVLANRASELLGGE 122 Query: 121 RGEDRLIHPNDDVNRGQSSNDIFPTAMHVAACMAVATHLIPALHTLRGTLAEKSSQFADI 180 RGE RL+HPNDDVNR QSSND+FPTAMHVAA A+ HL+P+L LR TLA K+ F DI Sbjct: 123 RGEARLVHPNDDVNRSQSSNDVFPTAMHVAAVTAITRHLLPSLRALRETLARKALDFDDI 182 Query: 181 VKIGRTHLQDATPLTLGQEFSGYVAQLEHAESAVIGTLNAISELAAGGTAVGTGLNAHPE 240 +KIGRTHLQDATPLTLGQEFSGY AQL+H+E+ + L + ELA GGTAVGTGLNA Sbjct: 183 IKIGRTHLQDATPLTLGQEFSGYAAQLQHSETHLNAALPHLCELALGGTAVGTGLNAPAG 242 Query: 241 FGERVAAELAKFFGFPFKTAPNKFAALAGHDALVASHGGLKTLAAALMKIANDVRWLASG 300 + E+VAAELA G PF T+PNKF +A D LV +HG LKTLAA+L KIAND+RWLASG Sbjct: 243 YAEQVAAELAALTGLPFVTSPNKFETMASADGLVHAHGALKTLAASLTKIANDIRWLASG 302 Query: 301 PRSGLGEITIPENEPGSSIMPGKVNPTQCEAMTMLCAQVFGNDVALNIGGASGNFELNVF 360 PRSGLGE++IPENEPGSSIMPGKVNPTQ EAMTMLCAQVFGNDVA+NIGGASGNFELNVF Sbjct: 303 PRSGLGELSIPENEPGSSIMPGKVNPTQSEAMTMLCAQVFGNDVAVNIGGASGNFELNVF 362 Query: 361 KPLIIHNFLQSVRLLADGMASFEEHCARGIEANHSRIGELMEKSLMLVTALAPHIGYDKA 420 +P+I +NFL S RLLADGM SF +HCA GIE N RI EL+++SLMLVTAL PHIGYDK+ Sbjct: 363 RPMIAYNFLHSARLLADGMRSFNDHCAVGIEPNRERIAELVQRSLMLVTALNPHIGYDKS 422 Query: 421 AKIAKQAHHDGTTLKQAALSLGYVTEEQFAEWIKPEQM 458 A+IAK+AH +GT+L++AAL+LGYVT EQF W++PEQM Sbjct: 423 AQIAKKAHKEGTSLREAALALGYVTAEQFDAWVRPEQM 460 >A9I7Z4.1 A9I7Z4_BORPD Fumarate hydratase class II EC=4.2.1.2 Length = 463 Score = 696 bits (1796), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/459 (74%), Positives = 384/459 (83%) Query: 1 MNHRMERDTFGLIEVPADRLWGAQTERSLHHFHISTERMPAELIVALAAVKRACASVNRD 60 M R E+DTFG IEVPAD LWGAQT+RSL F ISTERMP L+ A+A +KRA A VN + Sbjct: 1 MTTRTEKDTFGPIEVPADHLWGAQTQRSLQFFAISTERMPQPLVAAMARLKRAAAKVNAE 60 Query: 61 LGKLDGKKAEAIIAAADEVIAGKHPLEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGV 120 LG+LDGK A+AI+ AADEVIAGK P EFPLSVWQTGSGTQSNMNMNEVLANRASELLGGV Sbjct: 61 LGELDGKIADAIVRAADEVIAGKWPDEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGV 120 Query: 121 RGEDRLIHPNDDVNRGQSSNDIFPTAMHVAACMAVATHLIPALHTLRGTLAEKSSQFADI 180 RGE R +HPND VNRGQSSND FPTAMHVAA + V L+PAL LR TLA KS++F DI Sbjct: 121 RGEARRVHPNDHVNRGQSSNDTFPTAMHVAAALQVEHALLPALKALRATLAAKSAEFYDI 180 Query: 181 VKIGRTHLQDATPLTLGQEFSGYVAQLEHAESAVIGTLNAISELAAGGTAVGTGLNAHPE 240 VKIGRTHLQDATPLTLGQE SG+VAQL+ AE + L + +LA GGTAVGTGLNAHP Sbjct: 181 VKIGRTHLQDATPLTLGQELSGHVAQLDLAEQQIRAALPGLHQLAIGGTAVGTGLNAHPA 240 Query: 241 FGERVAAELAKFFGFPFKTAPNKFAALAGHDALVASHGGLKTLAAALMKIANDVRWLASG 300 F +V AELA G F +APNKF ALA H+AL+ +HG LK LAA LMKIANDVRWLASG Sbjct: 241 FSAKVCAELAHDTGSAFASAPNKFQALASHEALLFAHGALKALAAGLMKIANDVRWLASG 300 Query: 301 PRSGLGEITIPENEPGSSIMPGKVNPTQCEAMTMLCAQVFGNDVALNIGGASGNFELNVF 360 PRSGLGEI IPENEPGSSIMPGKVNPTQCEA+TML AQV GNDVA+NIGGASGNFELNVF Sbjct: 301 PRSGLGEIRIPENEPGSSIMPGKVNPTQCEAITMLAAQVMGNDVAINIGGASGNFELNVF 360 Query: 361 KPLIIHNFLQSVRLLADGMASFEEHCARGIEANHSRIGELMEKSLMLVTALAPHIGYDKA 420 KPL+IHNFLQSVRLLADGMASF++HCA GIE N RI EL+++SLMLVTAL PHIGYDKA Sbjct: 361 KPLVIHNFLQSVRLLADGMASFDQHCAAGIEPNRERIAELVDRSLMLVTALNPHIGYDKA 420 Query: 421 AKIAKQAHHDGTTLKQAALSLGYVTEEQFAEWIKPEQMT 459 A+IAK+AH + +LK AAL+LGYVTE++FA+W+ P +MT Sbjct: 421 AQIAKKAHKENLSLKDAALALGYVTEDEFAQWVVPGEMT 459