BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0029.0040.p (319 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IPX0.1 D8IPX0_HERSS D-isomer specific 2-hydroxyacid dehydrogen... 630 e-179 F0KXA8.1 F0KXA8_YERE3 Putative D-isomer specific 2-hydroxyacid d... 389 e-106 D4BY25.1 D4BY25_PRORE Glyoxylate/hydroxypyruvate reductase B 389 e-106 E7B955.1 E7B955_YERE1 Glyoxylate/hydroxypyruvate reductase B EC=... 384 e-104 A1JT62.1 GHRB_YERE8 Glyoxylate/hydroxypyruvate reductase B EC=1.... 382 e-104 C4U200.1 C4U200_YERKR Glyoxylate/hydroxypyruvate reductase B EC=... 379 e-103 A6W1N0.1 A6W1N0_MARMS D-isomer specific 2-hydroxyacid dehydrogen... 379 e-103 C4T1Y5.1 C4T1Y5_YERIN Glyoxylate/hydroxypyruvate reductase B EC=... 379 e-103 B9Z7V4.1 B9Z7V4_9NEIS D-isomer specific 2-hydroxyacid dehydrogen... 378 e-103 C4LFM3.1 C4LFM3_TOLAT D-isomer specific 2-hydroxyacid dehydrogen... 378 e-103 >D8IPX0.1 D8IPX0_HERSS D-isomer specific 2-hydroxyacid dehydrogenase protein EC=1.1.1.- Length = 319 Score = 630 bits (1625), Expect = e-179, Method: Compositional matrix adjust. Identities = 311/319 (97%), Positives = 314/319 (98%) Query: 1 MKPHVVVYKKLPEHLVQRLQAEFDLTLFDRITDDNRADFLAALKTAHGIIGASLPITNDM 60 MKPHVVVYKKLPEHLVQRLQAEFDLTLFDRITDDNRADF+AAL TAHG+IGASLPITN M Sbjct: 1 MKPHVVVYKKLPEHLVQRLQAEFDLTLFDRITDDNRADFIAALATAHGMIGASLPITNAM 60 Query: 61 LEGAPQLKIASTISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALILASARRVVE 120 LE APQLKI STISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALILASARRVVE Sbjct: 61 LEAAPQLKIVSTISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALILASARRVVE 120 Query: 121 LAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRRPD 180 LAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRRPD Sbjct: 121 LAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRRPD 180 Query: 181 PEAERELGARYVSKEDLLAQADFVCVMLPLTPQTERMFGAPEFALMKRSAIFINASRGRI 240 PEAERELGARYVSKEDLLAQADFVCVMLPLTPQTERMFGAPEFALMKRSAIFINASRGRI Sbjct: 181 PEAERELGARYVSKEDLLAQADFVCVMLPLTPQTERMFGAPEFALMKRSAIFINASRGRI 240 Query: 241 VDEAALIAALQDKTIHGAGLDVFEVEPLPLQSPLLKLPNVVALPHIGSATHETRLDMAEL 300 VDEAALIAALQDKTIHGAGLDVFEVEPLPLQSPLLKLPNVVALPHIGSATHETRL MAEL Sbjct: 241 VDEAALIAALQDKTIHGAGLDVFEVEPLPLQSPLLKLPNVVALPHIGSATHETRLAMAEL 300 Query: 301 AVTNLIAGVRGEPVAHLAV 319 AVTNLIAG+RGEPVAHLAV Sbjct: 301 AVTNLIAGLRGEPVAHLAV 319 >F0KXA8.1 F0KXA8_YERE3 Putative D-isomer specific 2-hydroxyacid dehydrogenase Length = 326 Score = 389 bits (999), Expect = e-106, Method: Compositional matrix adjust. Identities = 191/311 (61%), Positives = 235/311 (75%) Query: 1 MKPHVVVYKKLPEHLVQRLQAEFDLTLFDRITDDNRADFLAALKTAHGIIGASLPITNDM 60 MKP +V+YK +P L QRL+ F ++ FD ++ DN+ + L+AL+ A G+IG+ I Sbjct: 1 MKPSIVLYKSIPADLHQRLEQYFTVSSFDGLSSDNQPELLSALQQAEGLIGSGGKIDQAF 60 Query: 61 LEGAPQLKIASTISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALILASARRVVE 120 LE AP+L+ ASTISVG DNFD+D QRG+ L HTP VLTE ADT+ AL+L+SARRVVE Sbjct: 61 LERAPKLRAASTISVGYDNFDVDALSQRGIALMHTPTVLTETVADTMMALVLSSARRVVE 120 Query: 121 LAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRRPD 180 LAE VKAG W+ SIG+ FGV+VH KT+G++GMGRIG A+A+RAH GF MP+LY +RRP Sbjct: 121 LAERVKAGEWQDSIGDDWFGVDVHHKTIGILGMGRIGMALAQRAHFGFSMPVLYTSRRPH 180 Query: 181 PEAERELGARYVSKEDLLAQADFVCVMLPLTPQTERMFGAPEFALMKRSAIFINASRGRI 240 EAE+ GAR S + LLA+ DF+C+ LP+T QT M G + A MK SAI INA RG + Sbjct: 181 EEAEKRFGARRCSLDTLLAEVDFLCITLPMTEQTYHMIGREQLAKMKSSAILINAGRGPV 240 Query: 241 VDEAALIAALQDKTIHGAGLDVFEVEPLPLQSPLLKLPNVVALPHIGSATHETRLDMAEL 300 VDE ALIAALQD TIH AGLDVFE EPLP++SPLLKLPNVVA+PHIGSATHETR +MA Sbjct: 241 VDEQALIAALQDGTIHAAGLDVFEQEPLPVESPLLKLPNVVAVPHIGSATHETRYNMAAC 300 Query: 301 AVTNLIAGVRG 311 AV NLIA + G Sbjct: 301 AVDNLIAALTG 311 >D4BY25.1 D4BY25_PRORE Glyoxylate/hydroxypyruvate reductase B Length = 330 Score = 389 bits (998), Expect = e-106, Method: Compositional matrix adjust. Identities = 189/312 (60%), Positives = 232/312 (74%) Query: 1 MKPHVVVYKKLPEHLVQRLQAEFDLTLFDRITDDNRADFLAALKTAHGIIGASLPITNDM 60 MK ++++YK +P ++RLQ F++T+FD +T +N A F AL A GIIGAS PIT D Sbjct: 7 MKQNIILYKSIPTDQLERLQQHFNVTVFDSVTPENLASFKQALSRADGIIGASYPITADD 66 Query: 61 LEGAPQLKIASTISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALILASARRVVE 120 + AP LK ASTISVG+D FD+D R + L HTP VLTE TADTIF L+L SARR++E Sbjct: 67 IANAPNLKAASTISVGIDQFDIDAMNARKIALMHTPNVLTETTADTIFTLVLCSARRIIE 126 Query: 121 LAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRRPD 180 +AE VK G+W SIGE +G NV+GKT+G++GMGRIG AVA+RA+ GFGMP+LY+N Sbjct: 127 MAEMVKNGQWTQSIGEDAYGSNVNGKTIGILGMGRIGYAVAKRAYLGFGMPVLYYNNHIH 186 Query: 181 PEAERELGARYVSKEDLLAQADFVCVMLPLTPQTERMFGAPEFALMKRSAIFINASRGRI 240 P+AE +L AR + LLA++DFVCV+LPL+ TE++ G E A MK SA IN SRGRI Sbjct: 187 PDAETQLKARRCDLDTLLAESDFVCVVLPLSASTEKLIGKNELAKMKPSAFLINGSRGRI 246 Query: 241 VDEAALIAALQDKTIHGAGLDVFEVEPLPLQSPLLKLPNVVALPHIGSATHETRLDMAEL 300 VDEAALI AL+ TI GAGLDVFEVEPLP S LL LPNVVALPHIGSATHETR M E Sbjct: 247 VDEAALIDALESGTIRGAGLDVFEVEPLPSNSKLLTLPNVVALPHIGSATHETRYAMVEC 306 Query: 301 AVTNLIAGVRGE 312 AV NLIA ++G+ Sbjct: 307 AVDNLIAALKGD 318 >E7B955.1 E7B955_YERE1 Glyoxylate/hydroxypyruvate reductase B EC=1.1.1.79 EC=1.1.1.81 Length = 326 Score = 384 bits (986), Expect = e-104, Method: Compositional matrix adjust. Identities = 191/311 (61%), Positives = 232/311 (74%) Query: 1 MKPHVVVYKKLPEHLVQRLQAEFDLTLFDRITDDNRADFLAALKTAHGIIGASLPITNDM 60 MKP +V+YK +P L QRL+ F + FD +T +N + L+AL+ A G+IG+ I Sbjct: 1 MKPSIVLYKSIPADLHQRLEQYFTVNSFDGLTPNNHPELLSALQQAEGLIGSGGKIDQAF 60 Query: 61 LEGAPQLKIASTISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALILASARRVVE 120 LE AP+L+ ASTISVG DNFD+D QRG+ L HTP VLTE ADT+ AL L+SARRVVE Sbjct: 61 LERAPKLRAASTISVGYDNFDVDALSQRGIALMHTPTVLTETVADTMMALALSSARRVVE 120 Query: 121 LAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRRPD 180 LAE VKAG W+ SIG+ FGV+VH KT+G++GMGRIG A+A+RAH GF MP+LY +RRP Sbjct: 121 LAERVKAGEWQDSIGDDWFGVDVHHKTIGILGMGRIGMALAQRAHFGFSMPVLYTSRRPH 180 Query: 181 PEAERELGARYVSKEDLLAQADFVCVMLPLTPQTERMFGAPEFALMKRSAIFINASRGRI 240 EAE+ GAR S + LLA+ DF+C+ LP+T QT M G + A MK SAI INA RG + Sbjct: 181 EEAEKRFGARRCSLDTLLAEVDFLCITLPMTEQTYHMIGRDQLAKMKSSAILINAGRGPV 240 Query: 241 VDEAALIAALQDKTIHGAGLDVFEVEPLPLQSPLLKLPNVVALPHIGSATHETRLDMAEL 300 VDE ALIAALQD TIH AGLDVFE EPLP++SPLLKLPNVVA+PHIGSATHETR +MA Sbjct: 241 VDEQALIAALQDGTIHAAGLDVFEQEPLPVESPLLKLPNVVAVPHIGSATHETRYNMAAC 300 Query: 301 AVTNLIAGVRG 311 AV NLIA + G Sbjct: 301 AVDNLIAALTG 311 >A1JT62.1 GHRB_YERE8 Glyoxylate/hydroxypyruvate reductase B EC=1.1.1.79 EC=1.1.1.81 Length = 326 Score = 382 bits (982), Expect = e-104, Method: Compositional matrix adjust. Identities = 188/311 (60%), Positives = 232/311 (74%) Query: 1 MKPHVVVYKKLPEHLVQRLQAEFDLTLFDRITDDNRADFLAALKTAHGIIGASLPITNDM 60 MKP +V+YK +P L QRL+ F + F+ ++ DN+ + L+AL+ A G+IG+ I Sbjct: 1 MKPSIVLYKSIPADLHQRLEQHFTVNSFEGLSSDNQPELLSALQQAEGLIGSGGKIDQAF 60 Query: 61 LEGAPQLKIASTISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALILASARRVVE 120 LE AP+L+ ASTISVG DNFD+D QRG+ L HTP VLTE ADT+ AL+L+SARRVVE Sbjct: 61 LERAPKLRAASTISVGYDNFDVDALSQRGIALMHTPTVLTETVADTMMALVLSSARRVVE 120 Query: 121 LAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRRPD 180 LAE VKAG W+ SIG+ FGV+VH KT+G++GMGRIG A+A+RAH GF MP+LY +RRP Sbjct: 121 LAERVKAGEWQDSIGDDWFGVDVHHKTIGILGMGRIGMALAQRAHFGFSMPVLYTSRRPH 180 Query: 181 PEAERELGARYVSKEDLLAQADFVCVMLPLTPQTERMFGAPEFALMKRSAIFINASRGRI 240 AE+ GAR S + LLA+ DF+C+ LP+T QT M G + A MK SAI INA RG + Sbjct: 181 EAAEKRFGARRCSLDTLLAEVDFLCITLPMTEQTYHMIGPEQLAKMKSSAILINAGRGPV 240 Query: 241 VDEAALIAALQDKTIHGAGLDVFEVEPLPLQSPLLKLPNVVALPHIGSATHETRLDMAEL 300 VDE ALIAALQD TIH AGLDVF EPLP++SPLLKLPNVVA+PHIGSATHETR +MA Sbjct: 241 VDEQALIAALQDGTIHAAGLDVFAQEPLPVESPLLKLPNVVAVPHIGSATHETRYNMAAC 300 Query: 301 AVTNLIAGVRG 311 AV NLIA + G Sbjct: 301 AVDNLIAALTG 311 >C4U200.1 C4U200_YERKR Glyoxylate/hydroxypyruvate reductase B EC=1.1.1.79 EC=1.1.1.81 Length = 326 Score = 379 bits (974), Expect = e-103, Method: Compositional matrix adjust. Identities = 187/311 (60%), Positives = 232/311 (74%) Query: 1 MKPHVVVYKKLPEHLVQRLQAEFDLTLFDRITDDNRADFLAALKTAHGIIGASLPITNDM 60 MKP +V+YK +P L QRL+ F + F+ ++ DN+ + LAAL+ A G+IG+ I Sbjct: 1 MKPSIVLYKSIPADLHQRLEQHFTVNSFEGLSSDNQPELLAALQQAEGLIGSGGKIDQAF 60 Query: 61 LEGAPQLKIASTISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALILASARRVVE 120 L+ AP+L+ ASTISVG DNF +D QRG++L HTP VLTE ADT+ L+L++ARRVVE Sbjct: 61 LQLAPRLRAASTISVGYDNFAVDALSQRGIVLMHTPTVLTETVADTMMTLVLSTARRVVE 120 Query: 121 LAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRRPD 180 LAE VKAG W+ SIG+ FGV+VH KT+G++GMGRIG A+A+RAH GF MP+LY +RRP Sbjct: 121 LAERVKAGEWQDSIGDDWFGVDVHHKTMGILGMGRIGMALAQRAHFGFSMPVLYTSRRPH 180 Query: 181 PEAERELGARYVSKEDLLAQADFVCVMLPLTPQTERMFGAPEFALMKRSAIFINASRGRI 240 EAE+ GAR S + LLA+ DF+C+ LP+T QT M G + A MK SAI INA RG + Sbjct: 181 EEAEKRFGARRCSLDTLLAEVDFLCITLPMTEQTYHMIGREQLAKMKSSAILINAGRGPV 240 Query: 241 VDEAALIAALQDKTIHGAGLDVFEVEPLPLQSPLLKLPNVVALPHIGSATHETRLDMAEL 300 VDE ALIAALQ+ TIHGAGLDVFE EPLP SPLLKLPNVVA+PHIGSATHETR +MA Sbjct: 241 VDEQALIAALQEGTIHGAGLDVFEQEPLPADSPLLKLPNVVAVPHIGSATHETRYNMAAC 300 Query: 301 AVTNLIAGVRG 311 AV NLIA + G Sbjct: 301 AVDNLIAALTG 311 >A6W1N0.1 A6W1N0_MARMS D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Length = 327 Score = 379 bits (972), Expect = e-103, Method: Compositional matrix adjust. Identities = 180/318 (56%), Positives = 231/318 (72%) Query: 1 MKPHVVVYKKLPEHLVQRLQAEFDLTLFDRITDDNRADFLAALKTAHGIIGASLPITNDM 60 MK V++Y+ +P QRL+A++D+T F+ I +DN+ F+AAL A G+IG S +++++ Sbjct: 1 MKKKVILYRDIPVEERQRLEAQYDVTFFNSINEDNKGAFIAALADAEGLIGTSTKMSSEL 60 Query: 61 LEGAPQLKIASTISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALILASARRVVE 120 L AP+LK ASTISVG D +DL+Y +RG+ L HTPGVL E TADT+F LI+ +ARR VE Sbjct: 61 LSLAPKLKAASTISVGTDLYDLNYLTERGIPLMHTPGVLNETTADTMFTLIMCAARRAVE 120 Query: 121 LAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRRPD 180 L+ V+ GRW +IGEA +G +VHGKTLG+IGMGRIG A+A+R H GF M I Y NR Sbjct: 121 LSNMVREGRWTSNIGEALYGTDVHGKTLGIIGMGRIGYAIAKRGHFGFDMKIQYSNRSRK 180 Query: 181 PEAERELGARYVSKEDLLAQADFVCVMLPLTPQTERMFGAPEFALMKRSAIFINASRGRI 240 +AE+ L A Y+ E+LL +DFVCVM PLTP+TER+ GA EFA+MK+SAIFIN SRG++ Sbjct: 181 QDAEQTLSATYMEMEELLQTSDFVCVMTPLTPETERLIGAKEFAMMKKSAIFINGSRGKV 240 Query: 241 VDEAALIAALQDKTIHGAGLDVFEVEPLPLQSPLLKLPNVVALPHIGSATHETRLDMAEL 300 +DEAAL+ AL + TI AGLDVFEVEPL SPL KL N V PHIGSAT ETRL M Sbjct: 241 IDEAALVDALSNGTIRAAGLDVFEVEPLSGDSPLCKLDNAVLFPHIGSATAETRLAMITC 300 Query: 301 AVTNLIAGVRGEPVAHLA 318 AV NLI + G+ + A Sbjct: 301 AVDNLINALNGDISKNCA 318 >C4T1Y5.1 C4T1Y5_YERIN Glyoxylate/hydroxypyruvate reductase B EC=1.1.1.79 EC=1.1.1.81 Length = 330 Score = 379 bits (972), Expect = e-103, Method: Compositional matrix adjust. Identities = 187/311 (60%), Positives = 230/311 (73%) Query: 1 MKPHVVVYKKLPEHLVQRLQAEFDLTLFDRITDDNRADFLAALKTAHGIIGASLPITNDM 60 MKP +V+YK +P L QRL F + FD +T DN+ + L+AL+ A G+IG+ I D Sbjct: 5 MKPSIVLYKSIPSDLHQRLAQHFTVNSFDGLTPDNQPELLSALQQAQGLIGSGGKIDQDF 64 Query: 61 LEGAPQLKIASTISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALILASARRVVE 120 L+ AP+L+ ASTISVG DNFD+D QRG+ L HTP VLTE ADT+ AL+L+ ARRVVE Sbjct: 65 LQLAPRLRAASTISVGYDNFDVDALSQRGVALMHTPTVLTETVADTMMALVLSCARRVVE 124 Query: 121 LAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRRPD 180 LAE VKAG W+ SIG+ +GV+VH KT+G++GMGRIG A+A+RAH GF MP+LY +RRP Sbjct: 125 LAERVKAGEWQDSIGDDWYGVDVHHKTIGILGMGRIGMALAQRAHFGFSMPVLYTSRRPH 184 Query: 181 PEAERELGARYVSKEDLLAQADFVCVMLPLTPQTERMFGAPEFALMKRSAIFINASRGRI 240 EAE+ AR+ S + LLA+ DF+C+ LP+T QT M G + A MK SAI INA RG + Sbjct: 185 EEAEKRFNARFCSLDTLLAEVDFLCITLPMTEQTYHMIGRDQLAKMKSSAILINAGRGPV 244 Query: 241 VDEAALIAALQDKTIHGAGLDVFEVEPLPLQSPLLKLPNVVALPHIGSATHETRLDMAEL 300 VDE ALIAALQD TIHGAGLDVFE EPLP+ SPLL L NVVA+PHIGSAT ETR +MA Sbjct: 245 VDEQALIAALQDGTIHGAGLDVFEQEPLPIDSPLLSLRNVVAVPHIGSATTETRYNMAAC 304 Query: 301 AVTNLIAGVRG 311 AV NLIA + G Sbjct: 305 AVDNLIAALTG 315 >B9Z7V4.1 B9Z7V4_9NEIS D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Length = 335 Score = 378 bits (970), Expect = e-103, Method: Compositional matrix adjust. Identities = 197/312 (63%), Positives = 239/312 (76%) Query: 1 MKPHVVVYKKLPEHLVQRLQAEFDLTLFDRITDDNRADFLAALKTAHGIIGASLPITNDM 60 MK VV YKKLP L+ RL +F++ FD + D NRA F A+ AHG+IG+S+ I + Sbjct: 4 MKKRVVAYKKLPPALLARLAEQFEVIGFDGVNDTNRAAFAEAVAGAHGLIGSSVRIDATL 63 Query: 61 LEGAPQLKIASTISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALILASARRVVE 120 L+ A +L++ STISVG D FD+DY +RG++LA+TP VLTE TADT+FALILA+ARRVVE Sbjct: 64 LDPARELELISTISVGYDTFDVDYLTRRGILLANTPDVLTETTADTLFALILATARRVVE 123 Query: 121 LAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRRPD 180 LAE+VKAG W+ SIG A FGV+VH KTLGLIG+GRIG AVARRA+ GFGM ++Y++R Sbjct: 124 LAEFVKAGHWQRSIGPAHFGVDVHHKTLGLIGLGRIGQAVARRANLGFGMNVVYYSRHAV 183 Query: 181 PEAERELGARYVSKEDLLAQADFVCVMLPLTPQTERMFGAPEFALMKRSAIFINASRGRI 240 PEAE GAR V +L A ADFVCV+LPLT +T+++ A FA M+ IFIN SRG I Sbjct: 184 PEAEAAYGARRVGLNELYASADFVCVVLPLTAETDKLIDADAFARMRPETIFINGSRGPI 243 Query: 241 VDEAALIAALQDKTIHGAGLDVFEVEPLPLQSPLLKLPNVVALPHIGSATHETRLDMAEL 300 VDEAALI AL+ IHGAGLDVFE EPLP SPLL+LPNVVALPHIGSATHETR MAE+ Sbjct: 244 VDEAALIQALKSGAIHGAGLDVFEREPLPADSPLLQLPNVVALPHIGSATHETRFAMAEM 303 Query: 301 AVTNLIAGVRGE 312 AV NLIAG+ G+ Sbjct: 304 AVDNLIAGLNGQ 315 >C4LFM3.1 C4LFM3_TOLAT D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Length = 324 Score = 378 bits (970), Expect = e-103, Method: Compositional matrix adjust. Identities = 181/317 (57%), Positives = 232/317 (73%) Query: 1 MKPHVVVYKKLPEHLVQRLQAEFDLTLFDRITDDNRADFLAALKTAHGIIGASLPITNDM 60 MKP+VV+Y+K+P+ L+ +LQ + +T FD I DNRA F+ AL A G+IG L ++++ Sbjct: 1 MKPNVVLYRKIPDDLLAKLQEQCQVTYFDGINADNRAAFIKALAEAEGVIGVGLQFSDEL 60 Query: 61 LEGAPQLKIASTISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALILASARRVVE 120 + AP+LK STISVG D+F++ RG+ L HTPGVLTE TADTIF L+L +ARR+ E Sbjct: 61 MAAAPKLKAVSTISVGYDDFNVAKLSARGIALMHTPGVLTETTADTIFTLVLCAARRITE 120 Query: 121 LAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRRPD 180 LAE VK G W+GSIG +G NVHGKT+G++GMGRIG AVA+RAH GFGM ++Y+NR Sbjct: 121 LAEKVKQGEWQGSIGPDWYGSNVHGKTIGILGMGRIGYAVAKRAHFGFGMNVIYYNRSAK 180 Query: 181 PEAERELGARYVSKEDLLAQADFVCVMLPLTPQTERMFGAPEFALMKRSAIFINASRGRI 240 PEAE++L AR S ++LLA ADFVC +LPL P+T + A MK SA FIN RG Sbjct: 181 PEAEQQLNARRCSLDELLADADFVCNVLPLMPETRHIINRDTLAKMKPSAFFINGGRGAS 240 Query: 241 VDEAALIAALQDKTIHGAGLDVFEVEPLPLQSPLLKLPNVVALPHIGSATHETRLDMAEL 300 VDEAAL+ AL+ I GAGLDVFE EPLP+ S LL LPNVVALPHIGSATHETR +M+++ Sbjct: 241 VDEAALVEALKSGVIKGAGLDVFETEPLPVNSELLSLPNVVALPHIGSATHETRYEMSKM 300 Query: 301 AVTNLIAGVRGEPVAHL 317 AV NL+A ++G+ H Sbjct: 301 AVENLLAALKGDLTKHC 317