BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0165.p (448 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IT62.1 D8IT62_HERSS Signal transduction containing EAL and mod... 916 0.0 A6SXL7.1 A6SXL7_JANMA Signal transduction protein 472 e-131 A4G6Y4.1 A4G6Y4_HERAR Putative uncharacterized protein 464 e-128 Q2Y9D6.1 Q2Y9D6_NITMU Diguanylate phosphodiesterase (EAL domain) 421 e-115 B9TN42.1 B9TN42_RICCO Putative uncharacterized protein (Fragment) 306 6e-81 Q47AV1.1 Q47AV1_DECAR EAL protein 302 7e-80 A5G5T5.1 A5G5T5_GEOUR Diguanylate phosphodiesterase 293 5e-77 B9M9Q3.1 B9M9Q3_GEOSF Diguanylate phosphodiesterase 285 1e-74 Q39SY2.1 Q39SY2_GEOMG Diguanylate phosphodiesterase (EAL domain) 281 1e-73 B3EAK7.1 B3EAK7_GEOLS Diguanylate phosphodiesterase 280 3e-73 >D8IT62.1 D8IT62_HERSS Signal transduction containing EAL and modified HD-GYP domains protein Length = 448 Score = 916 bits (2367), Expect = 0.0, Method: Compositional matrix adjust. Identities = 448/448 (100%), Positives = 448/448 (100%) Query: 1 MSDQSSDQSTSTHQALDFYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVI 60 MSDQSSDQSTSTHQALDFYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVI Sbjct: 1 MSDQSSDQSTSTHQALDFYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVI 60 Query: 61 AHASELGLSNVIGNLQGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVREL 120 AHASELGLSNVIGNLQGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVREL Sbjct: 61 AHASELGLSNVIGNLQGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVREL 120 Query: 121 VKAGYVFALDDVVAESQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKV 180 VKAGYVFALDDVVAESQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKV Sbjct: 121 VKAGYVFALDDVVAESQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKV 180 Query: 181 ETLQQFNDCVTFGFDYFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFI 240 ETLQQFNDCVTFGFDYFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFI Sbjct: 181 ETLQQFNDCVTFGFDYFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFI 240 Query: 241 KRDVALSLTLLRLVNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTM 300 KRDVALSLTLLRLVNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTM Sbjct: 241 KRDVALSLTLLRLVNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTM 300 Query: 301 SPLMILAATRGKMLELITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVST 360 SPLMILAATRGKMLELITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVST Sbjct: 301 SPLMILAATRGKMLELITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVST 360 Query: 361 EIREALLRRTGFYGVALRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNS 420 EIREALLRRTGFYGVALRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNS Sbjct: 361 EIREALLRRTGFYGVALRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNS 420 Query: 421 ISNNNIGAQASMHMSPPPEGFIDDDDDD 448 ISNNNIGAQASMHMSPPPEGFIDDDDDD Sbjct: 421 ISNNNIGAQASMHMSPPPEGFIDDDDDD 448 >A6SXL7.1 A6SXL7_JANMA Signal transduction protein Length = 425 Score = 472 bits (1214), Expect = e-131, Method: Compositional matrix adjust. Identities = 238/407 (58%), Positives = 303/407 (74%), Gaps = 1/407 (0%) Query: 17 DFYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVIAHASELGLSNVIGNLQ 76 +F+LARQPIL+ +Q L+ YELLFR A+ GPANV DD+ ATA+VIAHASELG+ NVIGN Sbjct: 18 EFFLARQPILNNDQDLVAYELLFRRASSGPANVVDDLAATASVIAHASELGIGNVIGNSL 77 Query: 77 GFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDVVAES 136 GF NVDAAVLM DF+ FLP+DKVVLEILETV +T ELV RV ELV G+ FALDDV++ S Sbjct: 78 GFFNVDAAVLMCDFVNFLPSDKVVLEILETVEITHELVERVSELVAQGFTFALDDVISHS 137 Query: 137 QEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQFNDCVTFGFDY 196 +++LLPL+KIIKID+ + ++L KL+ HF+ K LLAEKVET +QF C+ GF Y Sbjct: 138 DALKDLLPLIKIIKIDITGMSTTELGKLADHFRLEDKLLLAEKVETQEQFEACMKLGFHY 197 Query: 197 FQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFIKRDVALSLTLLRLVNT 256 FQGYYFA+P+IL GKKL S++ IM L+ L++ + D EI R IK+D +L LTLLRL NT Sbjct: 198 FQGYYFARPVILSGKKLAPSQLAIMQLMALIMADADTAEIERNIKKDASLVLTLLRLANT 257 Query: 257 PVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLMILAATRGKMLEL 316 P G + IDSLGQAL VLGRRQL+RWLQI+L+A +K +H SPL+ LA TRGK+LEL Sbjct: 258 PGVGVTQRIDSLGQALTVLGRRQLQRWLQIILYAEHNK-GSHFTSPLLQLATTRGKLLEL 316 Query: 317 ITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIREALLRRTGFYGVA 376 IT ++RP R M++ AFTVGIMSL+D LF SME +L Q++V E+ +ALL R GFYG Sbjct: 317 ITEKLRPDNRSMADTAFTVGIMSLMDTLFSQSMEEILDQVSVVEEVTDALLYRKGFYGDL 376 Query: 377 LRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNSISN 423 L+L E EQ ++ A + L +LQLS +D + + AFEW N++S Sbjct: 377 LKLAEYIEQIEKTGALLIPTLQKLQLSIEDLYALQLAAFEWSNNVSG 423 >A4G6Y4.1 A4G6Y4_HERAR Putative uncharacterized protein Length = 425 Score = 464 bits (1193), Expect = e-128, Method: Compositional matrix adjust. Identities = 233/406 (57%), Positives = 299/406 (73%), Gaps = 1/406 (0%) Query: 17 DFYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVIAHASELGLSNVIGNLQ 76 +F+LARQPIL+ EQ+L+ YELLFR A GPANV DD+ ATA+VIAHASELG+ NVIG Sbjct: 19 EFFLARQPILNSEQNLVAYELLFRRALSGPANVVDDLAATASVIAHASELGIVNVIGASL 78 Query: 77 GFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDVVAES 136 GF NVDAAVLM DF+ FLP +KVVLEILETV VTPELV RV EL G+ FALDDV++ + Sbjct: 79 GFFNVDAAVLMRDFVNFLPCEKVVLEILETVEVTPELVARVAELSAQGFTFALDDVISHT 138 Query: 137 QEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQFNDCVTFGFDY 196 + +++LLPLVKIIKID+ + +++ KL +F+R K LLAEKVET++QF DC+ GF Y Sbjct: 139 EALQKLLPLVKIIKIDITGMTKAEIAKLVDYFRRDDKLLLAEKVETIEQFQDCMDLGFHY 198 Query: 197 FQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFIKRDVALSLTLLRLVNT 256 FQGYYFA+P+IL GKKL S++ +M L+ L++ + D +I IK+D +L LTLLRL NT Sbjct: 199 FQGYYFARPVILSGKKLAPSQLAVMQLMALIMADADTADIEAIIKKDASLVLTLLRLTNT 258 Query: 257 PVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLMILAATRGKMLEL 316 P G + IDSL QAL VLGRRQL+RWLQI+L+A K SPL+ LA TRGK+LEL Sbjct: 259 PGLGVTRRIDSLSQALTVLGRRQLQRWLQIILYAEHHKGSQFN-SPLLQLATTRGKLLEL 317 Query: 317 ITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIREALLRRTGFYGVA 376 IT ++RPG+R M++ AFTVGIMSL+D LFG SM+ +L Q+ V ++ ALL R GFYG Sbjct: 318 ITEKLRPGQRAMADTAFTVGIMSLMDTLFGQSMQQILEQVAVVDDVSSALLARRGFYGDL 377 Query: 377 LRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNSIS 422 L+L E EQ ++ A + L +LQLS +D + + AFEW N +S Sbjct: 378 LKLAEYIEQIEKTGALLVPTLQKLQLSIEDLYALQLAAFEWSNIVS 423 >Q2Y9D6.1 Q2Y9D6_NITMU Diguanylate phosphodiesterase (EAL domain) Length = 424 Score = 421 bits (1081), Expect = e-115, Method: Compositional matrix adjust. Identities = 217/417 (52%), Positives = 288/417 (69%), Gaps = 1/417 (0%) Query: 5 SSDQSTSTHQALDFYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVIAHAS 64 ++ +S Q +F+LARQPIL + Q+LI YELLFR A +D A++IAH S Sbjct: 5 TAPHISSVGQVKEFFLARQPILDQNQNLIAYELLFRRAGVRAPVSAEDTRGAASIIAHTS 64 Query: 65 ELGLSNVIGNLQGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAG 124 ELG+ NV G+ GF NV++ +LM D + FLP +KVV E +T ++TPELV RV EL KAG Sbjct: 65 ELGIENVTGSALGFFNVNSTLLMGDLVNFLPAEKVVFEFPQTDKITPELVRRVAELAKAG 124 Query: 125 YVFALDDVVAESQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQ 184 Y FALDDV+ S+ I+ LLP V+IIKID + + L L FK+A+K LLA+KVETL+ Sbjct: 125 YRFALDDVITLSEYIKPLLPFVEIIKIDTSVMTYADLAMLVRQFKQARKVLLADKVETLE 184 Query: 185 QFNDCVTFGFDYFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFIKRDV 244 QF +C GFDY+QGYYFAKP +L GKKL S++ IM L+TL+ R+ D EI + IK++V Sbjct: 185 QFQNCHELGFDYYQGYYFAKPALLSGKKLATSQLAIMELMTLVARDADTIEIEQRIKKEV 244 Query: 245 ALSLTLLRLVNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLM 304 +L L+LLRLVNTP G K I SL +AL+VLGRRQL+RWLQI ++ D Q SPL+ Sbjct: 245 SLCLSLLRLVNTPAMGVTKSIHSLSEALMVLGRRQLQRWLQIQIYVGPDP-QIQFGSPLL 303 Query: 305 ILAATRGKMLELITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIRE 364 +LAATRGK+LEL+ +++P R M+++AFTVGI+SL+DALFG ME +LRQI +S EI E Sbjct: 304 LLAATRGKLLELVAQKLQPANRSMADIAFTVGILSLLDALFGQHMERILRQIVLSEEITE 363 Query: 365 ALLRRTGFYGVALRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNSI 421 ALL RTGFYG L+L E E+ + + LL L L ++ + + AFEW NS+ Sbjct: 364 ALLYRTGFYGDLLKLAEYLEKPGEAGRLLVPLLARLGLPIEELYPFQLEAFEWSNSL 420 >B9TN42.1 B9TN42_RICCO Putative uncharacterized protein (Fragment) Length = 272 Score = 306 bits (783), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 147/255 (57%), Positives = 193/255 (75%) Query: 17 DFYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVIAHASELGLSNVIGNLQ 76 +FYL RQPIL R Q L GYELLFR+A GPA+V +D++ATAAVIAHAS+LG+ IG+ Sbjct: 18 EFYLGRQPILDRNQALFGYELLFRNAPVGPAHVTNDLSATAAVIAHASQLGMEKTIGDAL 77 Query: 77 GFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDVVAES 136 GF+NVDA+VLMSD FLP DKVVLEIL TV++T ++V R+REL G+ FALDDV ES Sbjct: 78 GFVNVDASVLMSDIFSFLPRDKVVLEILNTVQITADVVSRIRELAGHGFRFALDDVTGES 137 Query: 137 QEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQFNDCVTFGFDY 196 E+ LLPLV +K+D+ + L KL+ F++ +K+L+AEKVET ++F +C+ GFDY Sbjct: 138 AEVAALLPLVDYVKMDMRNIALDTLSKLAPRFRQEKKKLVAEKVETREEFKNCLDLGFDY 197 Query: 197 FQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFIKRDVALSLTLLRLVNT 256 FQGYYFA+P+I+ GKKL S++ +M L+TL+ + DN +I R IKRDV+L+L LLRLVNT Sbjct: 198 FQGYYFARPVIMSGKKLSPSQLAVMELMTLVTSDADNHDIERAIKRDVSLALNLLRLVNT 257 Query: 257 PVYGFQKFIDSLGQA 271 P G ++ IDSL QA Sbjct: 258 PAVGARQRIDSLSQA 272 >Q47AV1.1 Q47AV1_DECAR EAL protein Length = 417 Score = 302 bits (774), Expect = 7e-80, Method: Compositional matrix adjust. Identities = 175/424 (41%), Positives = 260/424 (61%), Gaps = 15/424 (3%) Query: 1 MSDQSSDQSTSTHQALDFYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVI 60 M++ ++DQ +L RQ IL REQ L YELLFR+ + A V D V ATA VI Sbjct: 1 MNEAAADQ---------LFLGRQAILDREQRLHAYELLFRNGSRNFAEVTDGVQATATVI 51 Query: 61 AHA-SELGLSNVIGNLQGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRE 119 A+A +ELG+ +G +GFINVD L SD + LP VVLEILETV + ++ R + Sbjct: 52 ANAFTELGIEAALGQHRGFINVDEQFLFSDMLELLPRHAVVLEILETVPPSDAVIERCKA 111 Query: 120 LVKAGYVFALDDVVAESQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEK 179 L AG+ ALDDV+ + ELL LV+I+K+D+ + +L++L + K K+LLAEK Sbjct: 112 LKAAGFTLALDDVIQLEPQFAELLALVEIVKVDIQPLSRVQLMQLVMKLKPMGKQLLAEK 171 Query: 180 VETLQQFNDCVTFGFDYFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRF 239 V++ +Q C+ GF FQGYYFAKP I+ GKKL+ S++ +M L+ LL+ + D E+ Sbjct: 172 VDSREQMEQCLKLGFTLFQGYYFAKPTIIAGKKLDHSQLSLMKLMGLLLGDADTSELEAA 231 Query: 240 IKRDVALSLTLLRLVNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHT 299 +K + L++ LLR+ N+ G + I SLG A+ VLGRRQL+RWLQ+L+FA+ Q+ T Sbjct: 232 LKPEPGLTVNLLRMTNSVGAGGTERITSLGHAITVLGRRQLQRWLQLLVFASGG--QSPT 289 Query: 300 MSPLMILAATRGKMLELITTRIRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVS 359 +PL+ +AATRG+++EL+ + PG +++ AF VGIMSL+ L G + ++ + ++ Sbjct: 290 ENPLLQMAATRGRLMELLAGELSPGDNALADRAFMVGIMSLMPVLVGQPIADIVAPLGLA 349 Query: 360 TEIREALLRRTGFYGVALRLVECTEQRDQDQAEMQRLLDELQ-LSADDFFEAEKHAFEWG 418 T++R+AL +G G LR+ E +E + + AE+ L EL L A+ A +W Sbjct: 350 TDVRDALCAGSGPLGALLRIAESSE--NGNLAELATALTELPGLGPKAINRAQTQALQWA 407 Query: 419 NSIS 422 N I Sbjct: 408 NEIG 411 >A5G5T5.1 A5G5T5_GEOUR Diguanylate phosphodiesterase Length = 412 Score = 293 bits (749), Expect = 5e-77, Method: Compositional matrix adjust. Identities = 165/413 (39%), Positives = 261/413 (63%), Gaps = 15/413 (3%) Query: 18 FYLARQPILSREQHLIGYELLFRSA-AFGPANVKDDVTATAAVIAHA-SELGLSNVIGNL 75 ++L RQPIL R+Q +IG+ELLFRSA + AN+ D A+A+VI +A ++ G V+G Sbjct: 6 YFLGRQPILDRDQQIIGFELLFRSAESLLSANISDSFQASASVIVNALTDFGTKEVLGRH 65 Query: 76 QGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDVVAE 135 +GF NV+ +LM+D + LP ++VV+E+LET+ + +++ R R+L K G+ ALDD Sbjct: 66 KGFFNVNLDMLMNDTLELLPKEQVVIELLETIEINTDVIKRCRDLKKLGFTLALDDH-EY 124 Query: 136 SQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQFNDCVTFGFD 195 S E L PL+ I+K+D++E + L + + KR LAEKVET +Q++ C GF+ Sbjct: 125 SAAYEPLYPLIDIVKLDILENSCASLSEALMPLKRWPLTFLAEKVETAEQYSFCSAHGFE 184 Query: 196 YFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFIKRDVALSLTLLRLVN 255 FQGYYFA P++L+ +++ +++ + LL ++R+V+ EI K++ L+ LLRLVN Sbjct: 185 LFQGYYFAHPVVLKQNRVDIAQLTLTKLLEQVLRDVELREIEETFKQNPNLTYNLLRLVN 244 Query: 256 TPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLMILAATRGKMLE 315 + G ++ I +L AL+VLG +QLKRW+ + LFA+ K SPL+++AATRGK++E Sbjct: 245 SVAIGLRERIKTLRHALMVLGLQQLKRWIMLALFAS--KSVHGVFSPLLVIAATRGKLME 302 Query: 316 LITTR-----IRPGRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIREALLRRT 370 L+ + + P S+ AF GI+SLVD+LF +SME ++RQ+ ++ +IR+ALL R Sbjct: 303 LLVKKQPTLIVDP---DFSDRAFMTGILSLVDSLFEVSMEEMVRQLNLADDIRQALLTRE 359 Query: 371 GFYGVALRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNSISN 423 G G+ L+L E EQ D A++ LL + + D A+ W NS+++ Sbjct: 360 GPLGMILQLTEKLEQADFAGADL--LLKQTDIHLDHLLRAQMETINWTNSLTD 410 >B9M9Q3.1 B9M9Q3_GEOSF Diguanylate phosphodiesterase Length = 412 Score = 285 bits (729), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 160/409 (39%), Positives = 252/409 (61%), Gaps = 9/409 (2%) Query: 18 FYLARQPILSREQHLIGYELLFRSA-AFGPANVKDDVTATAAVIAHA-SELGLSNVIGNL 75 F+L RQPIL Q +IG+ELLFRSA + AN+ D A+A+VI +A ++ G + V+G Sbjct: 6 FFLGRQPILDINQKIIGFELLFRSAESLCSANITDSFQASASVIINALTDFGTNEVLGRH 65 Query: 76 QGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDVVAE 135 +G+ NVD +LMSD + LP ++VV+E+LET+ + +++ R REL K G+ ALDD Sbjct: 66 KGYFNVDLEMLMSDSLELLPREQVVVELLETIEINSQVIERCRELKKQGFTIALDDH-EY 124 Query: 136 SQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQFNDCVTFGFD 195 + EEL L IIK+D+++ P ++ ++ KR +LAEKVET +Q+ C GF Sbjct: 125 NPAFEELYTLTDIIKVDILQTSPERIPEMMQLLKRWPLTMLAEKVETAEQYAFCSAQGFQ 184 Query: 196 YFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFIKRDVALSLTLLRLVN 255 FQGY+FA P++L+ K+++ +++ + LL ++R + EI K + L+ LLRLVN Sbjct: 185 LFQGYFFAHPVVLKQKRVDIAQLTLTKLLEKVMREAELSEIEETFKENPNLTYNLLRLVN 244 Query: 256 TPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLMILAATRGKMLE 315 + G ++ I +L AL+VLG +QLKRW+ + L+A+ K SPL+ +AA+RGK++E Sbjct: 245 SVAIGLRERIKTLRHALMVLGLQQLKRWIMLALYAS--KSDQGVFSPLLEIAASRGKLME 302 Query: 316 LITTRIRP--GRRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIREALLRRTGFY 373 L+ + + S+ AF G++SLVD+LF +SME +++Q+ + +IR ALL R G Sbjct: 303 LLVKKQQALLVNTDFSDRAFMTGVLSLVDSLFEVSMEEMVQQLNLDDDIRRALLAREGIL 362 Query: 374 GVALRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNSIS 422 G L+L E EQ D A +L++ +L+ D EA+ W N ++ Sbjct: 363 GHFLQLTETVEQADFKMA--SQLMNRTKLTPDHLLEAQLETINWTNGLT 409 >Q39SY2.1 Q39SY2_GEOMG Diguanylate phosphodiesterase (EAL domain) Length = 411 Score = 281 bits (719), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 170/410 (41%), Positives = 249/410 (60%), Gaps = 10/410 (2%) Query: 18 FYLARQPILSREQHLIGYELLFRSAAFGPANVKDDVTATAAVIAHA-SELGLSNVIGNLQ 76 F+L RQPIL REQ L G+ELLFRSA ANV D + A+A+VI A S GL ++G + Sbjct: 6 FFLGRQPILDREQKLYGFELLFRSADTLHANVTDYLQASASVIFDALSSFGLREILGKHK 65 Query: 77 GFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDVVAES 136 GFINV+A VLMS+ + LP +KVV+E+LE V +T ++ R REL + G+ ALDD V + Sbjct: 66 GFINVNADVLMSEALELLPPEKVVIELLEHVPITETVINRCRELKEKGFSIALDDHVY-A 124 Query: 137 QEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQFNDCVTFGFDY 196 E L +V +IK+D+M +L F+ + +LLAEKVET +Q+ C GF Y Sbjct: 125 PVYEPLYEIVDVIKVDLMRTGMERLQSELETFRHWKPKLLAEKVETYEQYEQCEALGFTY 184 Query: 197 FQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFIKRDVALSLTLLRLVNT 256 FQGYYFA+P++L +++ ++ I+ L LV VD E+ K+ L + LLRLVN+ Sbjct: 185 FQGYYFARPVVLTRTRVDVGRLAIIKLFNQLVAEVDIDELESTFKQHPNLIINLLRLVNS 244 Query: 257 PVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLMILAATRGKMLEL 316 G + I S+ A++VLG QL+RW + LFANT QA +PL+++AATR +++EL Sbjct: 245 VSVGLKSRITSMRHAIMVLGYHQLRRWAMMALFANT--AQAVGDNPLLVMAATRARLMEL 302 Query: 317 ITTRIRPG---RRKMSEMAFTVGIMSLVDALFGMSMETVLRQITVSTEIREALLRRTGFY 373 I + +P R+ + AF GI+SL DAL M +E V+ + ++ ++R+ALL R G Sbjct: 303 IISE-QPTVLYDREYPDRAFMTGILSLADALLKMPIEEVVSPLNLNEDVRQALLAREGEL 361 Query: 374 GVALRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNSISN 423 G+ L+LVE E RD D + + L++ LS + + A W N + + Sbjct: 362 GILLQLVEKIE-RD-DFSAISPLIERFSLSMANLAPVQLAACNWVNGMDD 409 >B3EAK7.1 B3EAK7_GEOLS Diguanylate phosphodiesterase Length = 419 Score = 280 bits (717), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 159/411 (38%), Positives = 257/411 (62%), Gaps = 11/411 (2%) Query: 16 LDFYLARQPILSREQHLIGYELLFRSAAF-GPANVKDDVTATAAVIAHA-SELGLSNVIG 73 L F++ RQPIL+R+Q + GYELLFR+A+ A + A+A+VI+ A S+ GL +V+G Sbjct: 7 LKFFIGRQPILNRKQEIFGYELLFRAASHHTTAQFESQAQASASVISSALSDFGLQDVLG 66 Query: 74 NLQGFINVDAAVLMSDFIYFLPNDKVVLEILETVRVTPELVVRVRELVKAGYVFALDDVV 133 + GF+N+ A VL S+ + LP + VLEILET+ + + +R EL G+ ALDD + Sbjct: 67 DKFGFLNITAGVLHSEMLELLPIQQSVLEILETIELDDNVRLRCSELKSMGFKIALDDHI 126 Query: 134 AESQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRAQKELLAEKVETLQQFNDCVTFG 193 + E +V I+K+D+M DP++L ++ + ++ +LLAE+VET++ F C+ +G Sbjct: 127 Y-APEHSAFYKMVDIVKVDIMATDPAELSGIAANLRKYPVQLLAERVETVEVFEQCLEYG 185 Query: 194 FDYFQGYYFAKPMILQGKKLEASKMVIMHLLTLLVRNVDNGEIVRFIKRDVALSLTLLRL 253 F+ FQGY+F +P+I+ K+++ S + +M LL L N D E+ + + +L+ LL+L Sbjct: 186 FELFQGYFFERPVIIGQKRIDPSGIAMMKLLQQLNENWDIDEVEETFRENPSLTFNLLKL 245 Query: 254 VNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKEQAHTMSPLMILAATRGKM 313 VN+ + G ++ I ++ A+++LG L+RW+Q+ LFA D+ + SPL+ +AA RG++ Sbjct: 246 VNSVMIGLREKIKNIRHAIMILGINHLRRWVQLALFAGKDERGLN--SPLLEMAAVRGRL 303 Query: 314 LELITTRIRPGRRKMS---EMAFTVGIMSLVDALFGMSMETVLRQITVSTEIREALLRRT 370 +EL+ + R G+ + S E AF GI+SL+DAL+ ME V+ + +S ++ +ALLRR Sbjct: 304 MELLMMQ-RTGQSRTSDLVETAFLTGILSLLDALYETPMEHVVESLNLSEDMADALLRRD 362 Query: 371 GFYGVALRLVECTEQRDQDQAEMQRLLDELQLSADDFFEAEKHAFEWGNSI 421 G G+ L L E E+ D +Q+LLD L +S D A+ AF W NSI Sbjct: 363 GQLGMLLLLAERLEK--ADFVVVQKLLDALSISLDQLLAAQLDAFNWRNSI 411