BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0150.p (683 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IT78.1 D8IT78_HERSS Signal transduction containing PAS/GGDEF/E... 1400 0.0 C6X6V4.1 C6X6V4_METSD Diguanylate cyclase/phosphodiesterase with... 465 e-128 E4QJI7.1 E4QJI7_METS6 Diguanylate cyclase/phosphodiesterase with... 465 e-128 B6BNY2.1 B6BNY2_9PROT Ggdef domain protein 463 e-128 Q3A4W5.1 Q3A4W5_PELCD Response regulator receiver modulated digu... 459 e-126 D5X7K8.1 D5X7K8_THEPJ Diguanylate cyclase/phosphodiesterase with... 454 e-125 D5XDZ1.1 D5XDZ1_THEPJ Diguanylate cyclase/phosphodiesterase with... 452 e-125 E1MNL4.1 E1MNL4_9GAMM Diguanylate cyclase/phosphodiesterase with... 451 e-124 B1JF28.1 B1JF28_PSEPW Diguanylate cyclase/phosphodiesterase with... 451 e-124 E2XYF0.1 E2XYF0_PSEFL Putative diguanylate cyclase/phosphodieste... 447 e-123 >D8IT78.1 D8IT78_HERSS Signal transduction containing PAS/GGDEF/EAL domains protein Length = 683 Score = 1400 bits (3623), Expect = 0.0, Method: Compositional matrix adjust. Identities = 681/682 (99%), Positives = 682/682 (100%) Query: 1 MLSSVGTDDLACCSALLEAMQNLHGMALHAALGGIASGLLKRPGGRYVIGASAPVEGGLC 60 MLSSVGTDDLACCSALLEAMQNLHGMALHAALGGIASGLLKRPGGRYVIGASAPVEGGLC Sbjct: 1 MLSSVGTDDLACCSALLEAMQNLHGMALHAALGGIASGLLKRPGGRYVIGASAPVEGGLC 60 Query: 61 QPVQCEGALFGHFVFPPLTRPYSDQERQRLAMLAAFLGRLMQGRADTEQRVRALDQIEAK 120 QPVQCEGALFGHFVFPPLTRPYSDQERQRLAMLAAFLGRLMQGRADTEQRVRALDQIEAK Sbjct: 61 QPVQCEGALFGHFVFPPLTRPYSDQERQRLAMLAAFLGRLMQGRADTEQRVRALDQIEAK 120 Query: 121 LEQQAQILNQMHESVITMDPAGFITSWNRGAEQLFGYSAMEAIGRNVLFLYESEDEEDSL 180 LEQQAQILNQMHESVITMDPAGFITSWNRGAEQLFGYSAMEAIGRNVLFLYE+EDEEDSL Sbjct: 121 LEQQAQILNQMHESVITMDPAGFITSWNRGAEQLFGYSAMEAIGRNVLFLYENEDEEDSL 180 Query: 181 HDLFLEHGGREMEVRRRKKSGEVFWASLSLSVMRDQNGHPIGLIGYLNDITERKNAEKLI 240 HDLFLEHGGREMEVRRRKKSGEVFWASLSLSVMRDQNGHPIGLIGYLNDITERKNAEKLI Sbjct: 181 HDLFLEHGGREMEVRRRKKSGEVFWASLSLSVMRDQNGHPIGLIGYLNDITERKNAEKLI 240 Query: 241 HHLAYYDALTGLPNRTLLTRTVDQALEEARHENLHGCVMFIDLNRFKPINDTLGHVAGDM 300 HHLAYYDALTGLPNRTLLTRTVDQALEEARHENLHGCVMFIDLNRFKPINDTLGHVAGDM Sbjct: 241 HHLAYYDALTGLPNRTLLTRTVDQALEEARHENLHGCVMFIDLNRFKPINDTLGHVAGDM 300 Query: 301 LLVEVAMRLRRALREQDVVARLGADEFAVALFGIDKDSPAYVAQKLLALFDDPFFIDGHE 360 LLVEVAMRLRRALREQDVVARLGADEFAVALFGIDKDSPAYVAQKLLALFDDPFFIDGHE Sbjct: 301 LLVEVAMRLRRALREQDVVARLGADEFAVALFGIDKDSPAYVAQKLLALFDDPFFIDGHE 360 Query: 361 LRVGASIGVSLYPENATDTETLLRLADIAMYRAKQGGENNEGGYACYSEEMNRNTLDLLR 420 LRVGASIGVSLYPENATDTETLLRLADIAMYRAKQGGENNEGGYACYSEEMNRNTLDLLR Sbjct: 361 LRVGASIGVSLYPENATDTETLLRLADIAMYRAKQGGENNEGGYACYSEEMNRNTLDLLR 420 Query: 421 IETGLLHAFEYNELLLYYQPKVDMQTLAITGAEALVRWQHPERGLLLPGEFIPIAEETGL 480 IETGLLHAFEYNELLLYYQPKVDMQTLAITGAEALVRWQHPERGLLLPGEFIPIAEETGL Sbjct: 421 IETGLLHAFEYNELLLYYQPKVDMQTLAITGAEALVRWQHPERGLLLPGEFIPIAEETGL 480 Query: 481 IVQLSDWVLDAVCRQARAWKDAGLPPIRIALNVTAREFTRSLPDRVGAALERHMLSGEWL 540 IVQLSDWVLDAVCRQARAWKDAGLPPIRIALNVTAREFTRSLPDRVGAALERHMLSGEWL Sbjct: 481 IVQLSDWVLDAVCRQARAWKDAGLPPIRIALNVTAREFTRSLPDRVGAALERHMLSGEWL 540 Query: 541 ELEITESMLMHSTDRVISIMEKICGLGITVSLDDFGTGYSSLSYLKRFPINTLKIDRSFT 600 ELEITESMLMHSTDRVISIMEKICGLGITVSLDDFGTGYSSLSYLKRFPINTLKIDRSFT Sbjct: 541 ELEITESMLMHSTDRVISIMEKICGLGITVSLDDFGTGYSSLSYLKRFPINTLKIDRSFT 600 Query: 601 MGIPDDTNDCAIASAIIGIAKQLRHKVIAEGVEDEKQFNFLREAGCNELQGYIFSRPVPA 660 MGIPDDTNDCAIASAIIGIAKQLRHKVIAEGVEDEKQFNFLREAGCNELQGYIFSRPVPA Sbjct: 601 MGIPDDTNDCAIASAIIGIAKQLRHKVIAEGVEDEKQFNFLREAGCNELQGYIFSRPVPA 660 Query: 661 PDFHAMLLEGRKLALESASASQ 682 PDFHAMLLEGRKLALESASASQ Sbjct: 661 PDFHAMLLEGRKLALESASASQ 682 >C6X6V4.1 C6X6V4_METSD Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) Length = 1126 Score = 465 bits (1196), Expect = e-128, Method: Compositional matrix adjust. Identities = 253/556 (45%), Positives = 351/556 (63%), Gaps = 10/556 (1%) Query: 118 EAKLEQQAQILNQMHESVITMDPAGFITSWNRGAEQLFGYSAMEAIGR--NVLF--LYES 173 EA L Q+ + E ++ DPA + N+ +Q+ GY E IG+ +V+ L+E+ Sbjct: 559 EADLRLARQVFDNTAEGIVITDPAFRVLEVNQAYQQITGYDKEEIIGKLPSVMQAGLHEA 618 Query: 174 EDEEDSLHDLFLEHGGREMEVRRRKKSGEVFWASLSLSVMRDQNGHPIGLIGYLNDITER 233 E L E G E+ R+KSGE + LS+S + D G + DIT+R Sbjct: 619 AYYEGIWQTLRRE-GQWVGEIWNRRKSGESYPEWLSISQVADAKGSVQNYVAVFTDITQR 677 Query: 234 KNAEKLIHHLAYYDALTGLPNRTLLTRTVDQALEEARHENLHGCVMFIDLNRFKPINDTL 293 K +E+ + LA +DALT LPNR LL +DQAL A+ V+FIDL+RFK INDTL Sbjct: 678 KLSEERLQFLANHDALTHLPNRALLQERIDQALFRAQRNKTAIAVLFIDLDRFKIINDTL 737 Query: 294 GHVAGDMLLVEVAMRLRRALREQDVVARLGADEFAVALFGI-DKDSPAYVAQKLLALFDD 352 GH GDMLL E A RL+ LRE D VAR G DEF V + D D +A+K++A Sbjct: 738 GHQTGDMLLQEAAKRLKECLRETDTVARQGGDEFVVLVEDCGDTDYLNTIARKIMATLAQ 797 Query: 353 PFFIDGHELRVGASIGVSLYPENATDTETLLRLADIAMYRAKQGGENNEGGYACYSEEMN 412 PF + G EL + ASIG+S+YP++ DT +LL+ AD AMYRAK+ G+N + Y+ E N Sbjct: 798 PFILVGRELFISASIGISVYPDDGLDTASLLKHADAAMYRAKESGKNT---FRFYAAEAN 854 Query: 413 RNTLDLLRIETGLLHAFEYNELLLYYQPKVDMQTLAITGAEALVRWQHPERGLLLPGEFI 472 N+++LL +E L A E NE +L+YQPKVD+++ I GAEA+VRWQHPE G+L P +FI Sbjct: 855 TNSVELLTLENNLRRAVERNEFVLHYQPKVDLRSQKIIGAEAVVRWQHPELGMLSPMQFI 914 Query: 473 PIAEETGLIVQLSDWVLDAVCRQARAWKDAGLPPIRIALNVTAREF-TRSLPDRVGAALE 531 P+AEETGLI+ + W++ CRQA W+ +R+A+N++AR+F +L + AL Sbjct: 915 PLAEETGLIIDIGAWIMRESCRQAVEWQQLTGQNVRVAVNLSARQFRDETLRQTIADALT 974 Query: 532 RHMLSGEWLELEITESMLMHSTDRVISIMEKICGLGITVSLDDFGTGYSSLSYLKRFPIN 591 L+ + LELEITESM+MH+ +R +++ LG V +DDFGTGYSS YLK FPI+ Sbjct: 975 ESGLTPDCLELEITESMIMHNAERAREVLQHFHDLGAHVLIDDFGTGYSSFGYLKHFPID 1034 Query: 592 TLKIDRSFTMGIPDDTNDCAIASAIIGIAKQLRHKVIAEGVEDEKQFNFLREAGCNELQG 651 +LKIDRSF IPDD +D AI AII +A L+ KV+AEGVE ++Q FL++ GC+++QG Sbjct: 1035 SLKIDRSFVRDIPDDVDDMAITQAIIAMAHSLQIKVVAEGVETQEQLAFLKKQGCDQIQG 1094 Query: 652 YIFSRPVPAPDFHAML 667 ++FS P+ + DF ML Sbjct: 1095 FLFSEPLHSHDFVRML 1110 >E4QJI7.1 E4QJI7_METS6 Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) Length = 1126 Score = 465 bits (1196), Expect = e-128, Method: Compositional matrix adjust. Identities = 253/556 (45%), Positives = 350/556 (62%), Gaps = 10/556 (1%) Query: 118 EAKLEQQAQILNQMHESVITMDPAGFITSWNRGAEQLFGYSAMEAIGR--NVLF--LYES 173 EA L Q+ + E ++ DPA + N+ +Q+ GY E IG+ +V+ L+E+ Sbjct: 559 EADLRLARQVFDNTAEGIVITDPAFRVLEVNQAYQQITGYDKEEIIGKLPSVMQAGLHEA 618 Query: 174 EDEEDSLHDLFLEHGGREMEVRRRKKSGEVFWASLSLSVMRDQNGHPIGLIGYLNDITER 233 E L E G E+ R+KSGE + LS+S + D G + DIT+R Sbjct: 619 AYYEGIWQTLRRE-GQWVGEIWNRRKSGESYPEWLSISQVADAKGSVQNYVAVFTDITQR 677 Query: 234 KNAEKLIHHLAYYDALTGLPNRTLLTRTVDQALEEARHENLHGCVMFIDLNRFKPINDTL 293 K +E+ + LA +DALT LPNR LL +DQAL A+ V+FIDL+RFK INDTL Sbjct: 678 KLSEERLQFLANHDALTHLPNRALLQERIDQALFRAQRNKTAIAVLFIDLDRFKIINDTL 737 Query: 294 GHVAGDMLLVEVAMRLRRALREQDVVARLGADEFAVALFGI-DKDSPAYVAQKLLALFDD 352 GH GDMLL E A RL+ LRE D VAR G DEF V + D D +A+K++A Sbjct: 738 GHQTGDMLLQEAAKRLKECLRETDTVARQGGDEFVVLVEDCGDTDYLNTIARKIMATLAQ 797 Query: 353 PFFIDGHELRVGASIGVSLYPENATDTETLLRLADIAMYRAKQGGENNEGGYACYSEEMN 412 PF + G EL + ASIG+S+YP++ DT +LL+ AD AMYRAK+ G+N + Y+ E N Sbjct: 798 PFILVGRELFISASIGISVYPDDGLDTASLLKHADAAMYRAKESGKNT---FRFYAAEAN 854 Query: 413 RNTLDLLRIETGLLHAFEYNELLLYYQPKVDMQTLAITGAEALVRWQHPERGLLLPGEFI 472 N+++LL +E L A E NE +L+YQPKVD+++ I GAEA+VRWQHPE G+L P +FI Sbjct: 855 TNSVELLTLENNLRRAVERNEFVLHYQPKVDLRSQKIIGAEAVVRWQHPELGMLSPMQFI 914 Query: 473 PIAEETGLIVQLSDWVLDAVCRQARAWKDAGLPPIRIALNVTAREF-TRSLPDRVGAALE 531 P+AEETGLI+ + W++ CRQA W+ +R+A+N++AR+F +L + AL Sbjct: 915 PLAEETGLIIDIGAWIMQESCRQAVEWQQLTGQNVRVAVNLSARQFRDETLRQTIADALA 974 Query: 532 RHMLSGEWLELEITESMLMHSTDRVISIMEKICGLGITVSLDDFGTGYSSLSYLKRFPIN 591 L+ + LELEITESM+MH+ +R +++ LG V +DDFGTGYSS YLK FPI+ Sbjct: 975 ESGLTPDCLELEITESMIMHNAERAREVLQHFHDLGAHVLIDDFGTGYSSFGYLKHFPID 1034 Query: 592 TLKIDRSFTMGIPDDTNDCAIASAIIGIAKQLRHKVIAEGVEDEKQFNFLREAGCNELQG 651 +LKIDRSF IPDD +D AI AII +A L+ KV+AEGVE ++Q FL++ GC+++QG Sbjct: 1035 SLKIDRSFVRDIPDDVDDMAITQAIIAMAHSLQIKVVAEGVETQEQLAFLKKQGCDQIQG 1094 Query: 652 YIFSRPVPAPDFHAML 667 ++FS P+ DF ML Sbjct: 1095 FLFSEPLHTHDFVRML 1110 >B6BNY2.1 B6BNY2_9PROT Ggdef domain protein Length = 744 Score = 463 bits (1191), Expect = e-128, Method: Compositional matrix adjust. Identities = 238/577 (41%), Positives = 366/577 (63%), Gaps = 18/577 (3%) Query: 107 TEQRVRALDQIEAKLEQQAQILNQMHESVITMDPAGFITSWNRGAEQLFGYSAMEAIGRN 166 T + + + +++ K QQ QI+ Q+H+SVI+ D G+ITSWN+G++ L Y+ E + ++ Sbjct: 172 THRDITNIQEMQLKYSQQVQIIEQIHDSVISTDLNGYITSWNKGSQILLEYTEEEMLTKH 231 Query: 167 VLFLYESEDE---EDSLHDLFLEHGGREMEVRRRKKSGEVFWASLSLSVMRDQNGHPIGL 223 V L+ ED ++ +L ++HG + R KKSG++ + SLSLS+++D+ G+P L Sbjct: 232 VSSLFLEEDHKALQEGTQEL-IKHGEYHADKRLVKKSGDIIFVSLSLSILKDEKGNPTAL 290 Query: 224 IGYLNDITERKNAEK-------LIHHLAYYDALTGLPNRTLLTRTVDQALEEARHENLHG 276 +GY DIT+RK AE+ ++H+ A++D LT LPNRT ++QA+E+A+ Sbjct: 291 VGYCQDITKRKEAEEKLYEQKNILHYQAHHDELTQLPNRTFFNERLEQAIEKAKRNKTLI 350 Query: 277 CVMFIDLNRFKPINDTLGHVAGDMLLVEVAMRLRRALREQDVVARLGADEFAVAL--FGI 334 + +IDL+ FK IND+LGH GD++L A RL+ +R++D ++RLG DEF + + I Sbjct: 351 ALFYIDLDHFKQINDSLGHEVGDIVLKITAERLKNKIRKEDTLSRLGGDEFTLIIEELNI 410 Query: 335 DKDSPAYVAQKLLALFDDPFFIDGHELRVGASIGVSLYPENATDTETLLRLADIAMYRAK 394 KD + +AQK++ + P +ID H L + +SIG+S+YP++ TD + LL+ AD AMY+AK Sbjct: 411 AKDV-SLLAQKIIEDLEKPIYIDTHTLYISSSIGISIYPDDDTDAKNLLKYADSAMYKAK 469 Query: 395 QGGENNEGGYACYSEEMNRNTLDLLRIETGLLHAFEYNELLLYYQPKVDMQTLAITGAEA 454 + G NN + YS EM + + +E L A + E ++YYQP++D +T + G EA Sbjct: 470 EEGRNN---FQFYSSEMTELAFEHVAMEASLRQALQNEEFVVYYQPQMDGRTDRLVGMEA 526 Query: 455 LVRWQHPERGLLLPGEFIPIAEETGLIVQLSDWVLDAVCRQARAWKDAGLPPIRIALNVT 514 LVRW HP GL+ P +FIPIAE+ GLIVQ+ WV+ + Q AW GL P +A+N+ Sbjct: 527 LVRWNHPTLGLVQPYKFIPIAEKNGLIVQIDQWVMKSAMTQFVAWYKDGLNPGVLAMNLA 586 Query: 515 AREF-TRSLPDRVGAALERHMLSGEWLELEITESMLMHSTDRVISIMEKICGLGITVSLD 573 ++ + D + L+ EW+ELE+TES +M + I I+++I +GI +++D Sbjct: 587 VKQLQKKDFIDTMSNLLKSTQCKPEWIELEVTESQIMTNPQEAIKILKQISEMGIELAVD 646 Query: 574 DFGTGYSSLSYLKRFPINTLKIDRSFTMGIPDDTNDCAIASAIIGIAKQLRHKVIAEGVE 633 DFGTGYSSLSYLKR PI+ LKIDR+F +PDD D I ++I ++K L KVIAEGVE Sbjct: 647 DFGTGYSSLSYLKRLPIDKLKIDRTFIQDLPDDEEDVGITKSVIALSKSLNLKVIAEGVE 706 Query: 634 DEKQFNFLREAGCNELQGYIFSRPVPAPDFHAMLLEG 670 ++Q NFL E GC +QGY++S+P+ A + L+ Sbjct: 707 TDEQKNFLVENGCQNIQGYLYSKPITANEMKERFLKN 743 >Q3A4W5.1 Q3A4W5_PELCD Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) Length = 1274 Score = 459 bits (1180), Expect = e-126, Method: Compositional matrix adjust. Identities = 250/563 (44%), Positives = 348/563 (61%), Gaps = 12/563 (2%) Query: 116 QIEAKLEQQAQILNQMHESVITMDPAGFITSWNRGAEQLFGYSAMEAIGRNVLFLYESED 175 Q E++L++ ++ + Q SV+ DP G I N QL GY+ E I +N L +S + Sbjct: 681 QSESQLKKLSRAIEQSPVSVVITDPEGRIEYVNPKFTQLTGYTLEEVIAQNPRIL-KSGN 739 Query: 176 EEDSLHDLFLEH--GGREM--EVRRRKKSGEVFWASLSLSVMRDQNGHPIGLIGYLNDIT 231 S++D + G+E E+ ++K G +FW S S+S + D++G I IG DIT Sbjct: 740 LLPSVYDSLWKTITSGKEWYGELENKRKDGSIFWESASISPLFDESGKIINFIGVKEDIT 799 Query: 232 ERKNAEKLIHHLAYYDALTGLPNRTLLTRTVDQALEEARHENLHGCVMFIDLNRFKPIND 291 +RK EK + ++A +D LTGL NRTLL ++ AL +++ V+ +DL+RFK IND Sbjct: 800 QRKLNEKRLEYMATHDGLTGLANRTLLYDHLEIALHQSQRSKKLVAVILLDLDRFKVIND 859 Query: 292 TLGHVAGDMLLVEVAMRLRRALREQDVVARLGADEFAVALFGI-DKDSPAYVAQKLLALF 350 +LGH+ GD +L V RL++ +R D VARLG DEF V L + D + +A LL Sbjct: 860 SLGHLVGDQVLKAVGQRLKQYVRSTDTVARLGGDEFVVLLTDVRDTTAAGKIAHNLLRKL 919 Query: 351 DDPFFIDGHELRVGASIGVSLYPENATDTETLLRLADIAMYRAKQGGENNEGGYACYSEE 410 ++PFF+ G EL V AS G+ L + D LLR ADIAMY+AK G G YS E Sbjct: 920 NEPFFLHGRELYVSASFGICLSETDNVDGTILLRNADIAMYKAKAEG----CGLYFYSHE 975 Query: 411 MNRNTLDLLRIETGLLHAFEYNELLLYYQPKVDMQTLAITGAEALVRWQHPERGLLLPGE 470 MN + + L +E L A E NE LYYQPKV+ T I G EAL+RW+HP+RG++ P E Sbjct: 976 MNEHLIKTLEMENSLRQALEKNEFQLYYQPKVEHATGRIIGCEALLRWRHPQRGMIPPSE 1035 Query: 471 FIPIAEETGLIVQLSDWVLDAVCRQARAWKDAGLPPIRIALNVTAREFTR--SLPDRVGA 528 FIP+AEETGLIVQ+ WVL CRQ++ W+ GLPP+ +A+N++AR+F + +L V + Sbjct: 1036 FIPLAEETGLIVQIGHWVLAEACRQSKIWETEGLPPLTMAVNISARQFYQGENLIQAVKS 1095 Query: 529 ALERHMLSGEWLELEITESMLMHSTDRVISIMEKICGLGITVSLDDFGTGYSSLSYLKRF 588 LER L LELE+TESM+M M KI LG+++SLDDFGTGYSSL+YL+ F Sbjct: 1096 TLERSQLVPSQLELELTESMVMKDAVNAERTMRKIKQLGVSLSLDDFGTGYSSLNYLRSF 1155 Query: 589 PINTLKIDRSFTMGIPDDTNDCAIASAIIGIAKQLRHKVIAEGVEDEKQFNFLREAGCNE 648 P+++LKIDRSF + I D + AI ++II IA L + +AEGVE+ Q + GCN Sbjct: 1156 PVDSLKIDRSFILDIASDASSAAILNSIIAIAHTLGLQTVAEGVENNDQLALVANCGCNY 1215 Query: 649 LQGYIFSRPVPAPDFHAMLLEGR 671 +QGY+FSRP+P DF A+ L + Sbjct: 1216 IQGYLFSRPLPPEDFVALFLANK 1238 >D5X7K8.1 D5X7K8_THEPJ Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) Length = 798 Score = 454 bits (1169), Expect = e-125, Method: Compositional matrix adjust. Identities = 238/572 (41%), Positives = 352/572 (61%), Gaps = 16/572 (2%) Query: 105 ADTEQRVRALDQIEAKLEQQAQILNQMHESVITMDPAGFITSWNRGAEQLFGYSAMEAIG 164 +D +AL+++ + + +++ ++ G IT +N+ AE+L GY+A E IG Sbjct: 202 SDITDSKQALEELRQERDFSQSLVDNARTIIMLWAMDGTITLFNKYAEELTGYTAAEVIG 261 Query: 165 RNVLFLYESEDEEDSLHDLF--LEHG-----GREMEVRRRKKSGEVFWASLSLSVMRDQN 217 + ++ ++ + ++ +L + G G + + E+ W ++ D Sbjct: 262 KKWWEIFTPKEIKPAIPELLERFQQGEVIETGEHPWIAKDGGRIEILWTH---TLSYDAE 318 Query: 218 GHPIGLIGYLNDITERKNAEKLIHHLAYYDALTGLPNRTLLTRTVDQALEEARHENLHGC 277 G P+ +I DIT+RK AE++I+H+AY+D LT LPNR L + AL A+ Sbjct: 319 GKPLAIISMGIDITDRKRAEEIINHMAYHDPLTDLPNRALFNDRLKLALAHAKRNKQLLA 378 Query: 278 VMFIDLNRFKPINDTLGHVAGDMLLVEVAMRLRRALREQDVVARLGADEFAVALFGIDKD 337 VMFIDL+RFK INDTLGH GD +L +VA RL LRE D VAR+G DEF + I K+ Sbjct: 379 VMFIDLDRFKLINDTLGHAMGDRVLKDVAQRLTECLREGDTVARIGGDEFILIFPQIAKE 438 Query: 338 SP-AYVAQKLLALFDDPFFIDGHELRVGASIGVSLYPENATDTETLLRLADIAMYRAKQG 396 A +A K++ PF ++ E + SIGV++YP + D ETL++ AD A+Y AK+ Sbjct: 439 QDVAKIALKIIETMKRPFKVEMQEFHLTTSIGVAIYPHDGQDAETLVKNADSALYLAKEQ 498 Query: 397 GENNEGGYACYSEEMNRNTLDLLRIETGLLHAFEYNELLLYYQPKVDMQTLAITGAEALV 456 G Y Y+ MN + L E L A E +E ++YQP+V++ T ITG EALV Sbjct: 499 GNT----YQLYTPSMNDKAYERLNTEQALCKALENDEFEVHYQPQVNIITGQITGMEALV 554 Query: 457 RWQHPERGLLLPGEFIPIAEETGLIVQLSDWVLDAVCRQARAWKDAGLPPIRIALNVTAR 516 RW+HPE+GL+ PG+FI IAEETGLI+ + +WVL C Q++AW+DAG PP+ + +N++AR Sbjct: 555 RWKHPEKGLVYPGDFIQIAEETGLIIPIGEWVLRTACLQSKAWQDAGYPPVTVVVNLSAR 614 Query: 517 EF-TRSLPDRVGAALERHMLSGEWLELEITESMLMHSTDRVISIMEKICGLGITVSLDDF 575 +F ++L + + L+ + +WLELEITE ++M D + +++++ +GI +++DDF Sbjct: 615 QFLQQNLVETITRILQETGMDPKWLELEITEGVIMKDVDYTVKVLQELAKMGIRIAIDDF 674 Query: 576 GTGYSSLSYLKRFPINTLKIDRSFTMGIPDDTNDCAIASAIIGIAKQLRHKVIAEGVEDE 635 GTGYSSL+YLKRFPINTLKIDRSF G+ D D AI S II +A+ L KV+AEGVE E Sbjct: 675 GTGYSSLNYLKRFPINTLKIDRSFIQGVVSDIQDAAIVSTIIVLARNLNLKVVAEGVETE 734 Query: 636 KQFNFLREAGCNELQGYIFSRPVPAPDFHAML 667 +Q+ FLR C ++QGY FSRPVPA +F +L Sbjct: 735 EQYLFLRGKQCYDMQGYWFSRPVPAEEFEGLL 766 >D5XDZ1.1 D5XDZ1_THEPJ Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) Length = 1349 Score = 452 bits (1164), Expect = e-125, Method: Compositional matrix adjust. Identities = 245/572 (42%), Positives = 350/572 (61%), Gaps = 13/572 (2%) Query: 106 DTEQRVRALDQIEAKLEQQAQILNQMHESVITMDPAGFITSWNRGAEQLFGYSAMEAIGR 165 D +R +A I + E+ L+ + ++VIT D G IT N AE L G++ EA GR Sbjct: 775 DITERKQAEQAIWEEKERAQVTLHSIGDAVITTDGQGIITYLNPVAEVLTGWTNDEACGR 834 Query: 166 NVLFLYESEDE------EDSLHDLFLEHG--GREMEVRRRKKSGEVFWASLSLSVMRDQN 217 +L ++ +E E+ + E G +SG + S + ++++ Sbjct: 835 PLLEVFNIINETTGQVVENPVTKCLREGNIVGLANHTVLIHRSGRRYAIEDSAAPIKNRE 894 Query: 218 GHPIGLIGYLNDITERKNAEKLIHHLAYYDALTGLPNRTLLTRTVDQALEEARHENLHGC 277 G IG++ +D++E++N + + H AY+D LT +PNR L ++ AL A+ N Sbjct: 895 GEIIGVVLVFHDVSEKRNMIEQLTHQAYHDPLTDIPNRVLFNDRLNVALAHAKRNNEMLA 954 Query: 278 VMFIDLNRFKPINDTLGHVAGDMLLVEVAMRLRRALREQDVVARLGADEFAVALFGIDKD 337 VMF+DL+RFK +ND LGH GD LL EVA +L LR+ D +ARLG DEF + L I + Sbjct: 955 VMFLDLDRFKLVNDMLGHSIGDRLLQEVAKKLSICLRKGDTIARLGGDEFTLLLPQIKSE 1014 Query: 338 S-PAYVAQKLLALFDDPFFIDGHELRVGASIGVSLYPENATDTETLLRLADIAMYRAKQG 396 A +AQK+L F P + GHE + ASIGV+LYP + E L++ AD AMYRAK+ Sbjct: 1015 KEAAKIAQKILKAFQKPVTLSGHEFYITASIGVALYPSDGEKAEILMKNADTAMYRAKEQ 1074 Query: 397 GENNEGGYACYSEEMNRNTLDLLRIETGLLHAFEYNELLLYYQPKVDMQTLAITGAEALV 456 G N Y Y+ MN+ ++ + +E L HA E EL++YYQP V ++T ITG EAL+ Sbjct: 1075 GRNT---YQLYTPAMNKKIVERMAMENSLRHALERRELVVYYQPLVCIRTGRITGMEALI 1131 Query: 457 RWQHPERGLLLPGEFIPIAEETGLIVQLSDWVLDAVCRQARAWKDAGLPPIRIALNVTAR 516 RW+H E GL+ P EFIP+AEETGLI+ + +WVL C Q +AW+DAG P+R+ +N++A Sbjct: 1132 RWRHKELGLVPPAEFIPLAEETGLIIPIGEWVLRTACAQNKAWQDAGYMPVRVTVNLSAY 1191 Query: 517 EFT-RSLPDRVGAALERHMLSGEWLELEITESMLMHSTDRVISIMEKICGLGITVSLDDF 575 +F ++L + V L++ L ++LELEITES+ M D + ++ K+ +G+ +++DDF Sbjct: 1192 QFQHQNLVNTVAKTLKQTGLHPQYLELEITESIAMQDVDYTVDVLRKLREMGVQIAIDDF 1251 Query: 576 GTGYSSLSYLKRFPINTLKIDRSFTMGIPDDTNDCAIASAIIGIAKQLRHKVIAEGVEDE 635 GTGYSSL YLKRFPINTLKIDRSF I D ND AI S II + + + KVIAEGVE E Sbjct: 1252 GTGYSSLRYLKRFPINTLKIDRSFVRDIACDPNDAAIVSTIIVLCRNMNLKVIAEGVETE 1311 Query: 636 KQFNFLREAGCNELQGYIFSRPVPAPDFHAML 667 +Q NFL+ C E+QGY FS+PVP +F +L Sbjct: 1312 EQLNFLKNQHCYEMQGYFFSQPVPEKEFEELL 1343 >E1MNL4.1 E1MNL4_9GAMM Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(S) Length = 856 Score = 451 bits (1161), Expect = e-124, Method: Compositional matrix adjust. Identities = 250/577 (43%), Positives = 351/577 (60%), Gaps = 15/577 (2%) Query: 106 DTEQRVRAL----DQIEAKLEQQAQILN----QMHESVITMDPAGFITSWNRGAEQLFGY 157 D + VR + D + KL +Q Q + Q E +I D I N+ + GY Sbjct: 280 DVSRAVRTVGAVRDITKKKLAEQEQRIFATAFQTQEGIIVTDANQIIVRVNQAFTIITGY 339 Query: 158 SAMEAIGRNVLFLYESEDEE---DSLHDLFLEHGGREMEVRRRKKSGEVFWASLSLSVMR 214 S EAIG L + ++H G + E+ R K G ++ L+++ ++ Sbjct: 340 STEEAIGNKPSMLKSGRHDNFFYHAMHKTLHSEGYWQGEIMDRHKDGRIYPKWLTITAVK 399 Query: 215 DQNGHPIGLIGYLNDITERKNAEKLIHHLAYYDALTGLPNRTLLTRTVDQALEEARHENL 274 D + +G +DITERK AE+ IH+LA +D LTGLPNRT L + AL A+ N Sbjct: 400 DSDDKTTHYVGNFSDITERKRAEEHIHYLANFDWLTGLPNRTQLNDHLKYALSLAKRSNG 459 Query: 275 HGCVMFIDLNRFKPINDTLGHVAGDMLLVEVAMRLRRALREQDVVARLGADEFAVALFGI 334 H +MF+DL+ FK IND+LGH GD LL+++A RLR ALRE+D V RLG DEF + L G+ Sbjct: 460 HLALMFLDLDHFKDINDSLGHSIGDALLIKLAKRLRAALREEDTVTRLGGDEFILLLPGV 519 Query: 335 DKDSPAYVAQKLLALFDDPFFIDGHELRVGASIGVSLYPENATDTETLLRLADIAMYRAK 394 D A+VAQKLL + + I+ ++L + ASIG++LYPE+ D E L + AD AMYRAK Sbjct: 520 DAIGAAHVAQKLLDTIAESYRIEHYDLILTASIGIALYPEDGEDLEALSKSADTAMYRAK 579 Query: 395 QGGENNEGGYACYSEEMNRNTLDLLRIETGLLHAFEYNELLLYYQPKVDMQTLAITGAEA 454 Q G Y +++EM + L++ L HA + ++L ++YQP++ M+ AI GAEA Sbjct: 580 QEGRQ---CYRFFTQEMQARSARNLQLVNALRHALDRSQLQVHYQPQISMRDGAIIGAEA 636 Query: 455 LVRWQHPERGLLLPGEFIPIAEETGLIVQLSDWVLDAVCRQARAWKDAGLPPIRIALNVT 514 L+RWQHPE G++ P EFIP+AE +GLI+ + +WVL +QA+AW + G P+ +A+N++ Sbjct: 637 LLRWQHPELGMVSPAEFIPVAEGSGLILPIGEWVLRCAVQQAKAWVNEGFGPLIMAVNLS 696 Query: 515 AREFTR-SLPDRVGAALERHMLSGEWLELEITESMLMHSTDRVISIMEKICGLGITVSLD 573 A +F LP+ V L+ L E+LELE+TE + MH+ I++M + G+ +S+D Sbjct: 697 AVQFRHPDLPELVTRILDEEGLPPEYLELELTEGVAMHNPQSAIAVMNNLQERGVRMSID 756 Query: 574 DFGTGYSSLSYLKRFPINTLKIDRSFTMGIPDDTNDCAIASAIIGIAKQLRHKVIAEGVE 633 DFGTGYSSLSYLK F + LKID+SF I D D I SAII +AK L K IAEGVE Sbjct: 757 DFGTGYSSLSYLKEFKVYKLKIDQSFVRDISTDPEDKVIVSAIINLAKSLGLKTIAEGVE 816 Query: 634 DEKQFNFLREAGCNELQGYIFSRPVPAPDFHAMLLEG 670 E Q FLRE GC+E+QGY+FS+PV A F A+L +G Sbjct: 817 TEGQQAFLREQGCDEMQGYLFSKPVSAEQFDALLKQG 853 >B1JF28.1 B1JF28_PSEPW Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) Length = 1276 Score = 451 bits (1159), Expect = e-124, Method: Compositional matrix adjust. Identities = 244/595 (41%), Positives = 358/595 (60%), Gaps = 25/595 (4%) Query: 82 YSDQERQRLAMLAAFLGRLMQGRADTEQRVRALDQIEAKLEQQAQILNQMHESVITMDPA 141 + D+ER F G L GR ++QR + E L A + +++ DPA Sbjct: 689 WDDRER--------FEGVLGVGRDISQQR-----RAEKDLRMAATVFEHSTSAILITDPA 735 Query: 142 GFITSWNRGAEQLFGYSAMEAIGRNVLFLYESEDEEDSLHDLFLE---HGGREMEVRRRK 198 G+I N ++ GYS + + + L + +E L + + G E EV ++ Sbjct: 736 GYIVQANEAFSRVSGYSVSDVLDQLPSMLTVDDQQEGHLRYVLKQLHLRGSWEGEVWLKR 795 Query: 199 KSGEVFWASLSLSVMRDQNGHPIGLIGYLNDITERKNAEKLIHHLAYYDALTGLPNRTLL 258 +SGE + A + ++ + D G + + DI+ERK +E+ IH LAYYDALT LPNRTL Sbjct: 796 RSGEHYPAWVGITAVLDDEGDLASYVCFFTDISERKASEQRIHRLAYYDALTHLPNRTLF 855 Query: 259 TRTVDQALEEARHENLHGCVMFIDLNRFKPINDTLGHVAGDMLLVEVAMRLRRALREQDV 318 + AL++A + +MF+DL+RFKPIND+LGH AGD +L ++A+RL + + D Sbjct: 856 QDRLHTALQQAERQKSWVVLMFLDLDRFKPINDSLGHAAGDRMLKDMALRLLACVDDDDT 915 Query: 319 VARLGADEFAVALFG-----IDKDSPAYVAQKLLALFDDPFFIDGHELRVGASIGVSLYP 373 VAR+G DEF + L + + +VA+ +LA PF ++G E V ASIG++L P Sbjct: 916 VARMGGDEFTLLLQSRATREMALNRAIHVAENILASLVRPFVLEGREFFVTASIGIALSP 975 Query: 374 ENATDTETLLRLADIAMYRAKQGGENNEGGYACYSEEMNRNTLDLLRIETGLLHAFEYNE 433 ++ + L++ AD AMY AK+ G+NN + Y EMN + L+ L +E+ L HA E NE Sbjct: 976 QDGGELSQLMKNADTAMYHAKERGKNN---FQFYQAEMNASALERLELESDLRHALEQNE 1032 Query: 434 LLLYYQPKVDMQTLAITGAEALVRWQHPERGLLLPGEFIPIAEETGLIVQLSDWVLDAVC 493 +LYYQP+ +TGAEAL+RW+HP RGL+ PG+FIP+ EE GL+V + DWVL Sbjct: 1033 FILYYQPQFSGDGKRLTGAEALLRWRHPTRGLVPPGDFIPVIEELGLVVDVGDWVLREAS 1092 Query: 494 RQARAWKDAGLPPIRIALNVTAREFTR-SLPDRVGAALERHMLSGEWLELEITESMLMHS 552 RQ +AW A + ++++N++AR+F+ L R+ LE L LELE+TES+LM Sbjct: 1093 RQLKAWHKAKVRVPKVSVNISARQFSDGQLGKRIATVLEETGLPPACLELELTESILMRD 1152 Query: 553 TDRVISIMEKICGLGITVSLDDFGTGYSSLSYLKRFPINTLKIDRSFTMGIPDDTNDCAI 612 + + I++ + LG+++++DDFGTGYSSL+YLK+FPI+ LKIDR+F G+P+ D I Sbjct: 1153 VNEAMQILDSLKVLGLSIAVDDFGTGYSSLNYLKQFPIDVLKIDRTFVDGLPEGEQDAQI 1212 Query: 613 ASAIIGIAKQLRHKVIAEGVEDEKQFNFLREAGCNELQGYIFSRPVPAPDFHAML 667 A AII +A L VIAEGVE +Q FLRE GC+E+QGY+F RP+PA F A Sbjct: 1213 ARAIIAMAHSLNLAVIAEGVETHEQLEFLREHGCDEVQGYLFGRPMPASQFEAQF 1267 >E2XYF0.1 E2XYF0_PSEFL Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(S) Length = 1283 Score = 447 bits (1150), Expect = e-123, Method: Compositional matrix adjust. Identities = 239/582 (41%), Positives = 353/582 (60%), Gaps = 17/582 (2%) Query: 95 AFLGRLMQGRADTEQRVRALDQIEAKLEQQAQILNQMHESVITMDPAGFITSWNRGAEQL 154 AF G L GR ++QR + E L A + +++ DPAG+I N ++ Sbjct: 701 AFEGILGVGRDISQQR-----RAEKDLRMAATVFEHSTSAILITDPAGYIVQANEAFSRV 755 Query: 155 FGYSAMEAIGRNVLFLYESEDEEDSLHDLFLE---HGGREMEVRRRKKSGEVFWASLSLS 211 GY+ + + + L E +E L + + H E EV ++++GE + A + ++ Sbjct: 756 SGYAVSDVLDQLPNMLTVDEQQEAHLRYVLKQLHQHSTWEGEVWLKRRNGEHYPAWVGIT 815 Query: 212 VMRDQNGHPIGLIGYLNDITERKNAEKLIHHLAYYDALTGLPNRTLLTRTVDQALEEARH 271 + D G + + +DI+ERK +E+ IH LAYYDALT LPNRTL + AL+ A Sbjct: 816 AVFDDEGDLASYVCFFSDISERKASEQRIHRLAYYDALTHLPNRTLFQDRLHTALQAAER 875 Query: 272 ENLHGCVMFIDLNRFKPINDTLGHVAGDMLLVEVAMRLRRALREQDVVARLGADEFAVAL 331 + +MF+DL+RFKPIND+LGH AGD +L E+A RL + E D VAR+G DEF + L Sbjct: 876 QKSWVVLMFLDLDRFKPINDSLGHAAGDRMLKEMATRLLGCVAEDDTVARMGGDEFTLLL 935 Query: 332 -----FGIDKDSPAYVAQKLLALFDDPFFIDGHELRVGASIGVSLYPENATDTETLLRLA 386 + + +VA+++LA PF ++G E V ASIG++L P++ + L++ A Sbjct: 936 QPRVNREMALNRAIHVAEQILASLVKPFVLEGREFFVTASIGIALSPQDGNELSQLMKNA 995 Query: 387 DIAMYRAKQGGENNEGGYACYSEEMNRNTLDLLRIETGLLHAFEYNELLLYYQPKVDMQT 446 D AMY AK+ G+NN + Y +MN + L+ L +E+ L HA E NE +LYYQP+ Sbjct: 996 DTAMYHAKERGKNN---FQFYQADMNASALERLELESDLRHALEQNEFVLYYQPQFSGDG 1052 Query: 447 LAITGAEALVRWQHPERGLLLPGEFIPIAEETGLIVQLSDWVLDAVCRQARAWKDAGLPP 506 +TGAEAL+RW+HP RGL+ PG+FIP+ EE GL+V + DWV+ CRQ + W + Sbjct: 1053 KRLTGAEALLRWRHPRRGLVPPGDFIPVLEELGLVVDVGDWVISEACRQLKTWHQNKVRV 1112 Query: 507 IRIALNVTAREFTR-SLPDRVGAALERHMLSGEWLELEITESMLMHSTDRVISIMEKICG 565 ++++N++AR+F+ L R+ L+ L LELE+TES+LM + + I++ + Sbjct: 1113 PKVSVNISARQFSDGQLGTRIATILKDTGLPPACLELELTESILMREVNEALHILDSLKN 1172 Query: 566 LGITVSLDDFGTGYSSLSYLKRFPINTLKIDRSFTMGIPDDTNDCAIASAIIGIAKQLRH 625 LG+++++DDFGTGYSSL+YLK+FPI+ LKIDR+F G+P D IA AII +A L Sbjct: 1173 LGLSIAVDDFGTGYSSLNYLKQFPIDVLKIDRTFVDGLPSGEQDAQIARAIIAMAHSLNL 1232 Query: 626 KVIAEGVEDEKQFNFLREAGCNELQGYIFSRPVPAPDFHAML 667 VIAEGVE +Q +FLRE GC+E+QGY+F RP+PA F A Sbjct: 1233 AVIAEGVETHEQLDFLREHGCDEVQGYLFGRPMPAHRFEAQF 1274