BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0086.p (229 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IU37.1 D8IU37_HERSS Two component response regulator protein 469 e-130 E4QNJ2.1 E4QNJ2_METS6 Two component transcriptional regulator, w... 324 5e-87 C6XD74.1 C6XD74_METSD Two component transcriptional regulator, w... 324 6e-87 Q47I71.1 Q47I71_DECAR Response regulator receiver:Transcriptiona... 313 1e-83 D9SHT0.1 D9SHT0_GALCS Two component transcriptional regulator, w... 313 2e-83 C6WWD2.1 C6WWD2_METML Two component transcriptional regulator, w... 303 1e-80 D7DJ12.1 D7DJ12_METS0 Two component transcriptional regulator, w... 301 6e-80 B9YZ56.1 B9YZ56_9NEIS Two component transcriptional regulator, w... 300 1e-79 C4LC20.1 C4LC20_TOLAT Two component transcriptional regulator, w... 281 6e-74 D7DQ34.1 D7DQ34_METS0 Two component transcriptional regulator, w... 276 1e-72 >D8IU37.1 D8IU37_HERSS Two component response regulator protein Length = 229 Score = 469 bits (1207), Expect = e-130, Method: Compositional matrix adjust. Identities = 229/229 (100%), Positives = 229/229 (100%) Query: 1 MSKVLLIDDDVELVDMLKEYLEQEKFEVNVAYDGEAGAAEALTGQYAIAVLDVMMPRLNG 60 MSKVLLIDDDVELVDMLKEYLEQEKFEVNVAYDGEAGAAEALTGQYAIAVLDVMMPRLNG Sbjct: 1 MSKVLLIDDDVELVDMLKEYLEQEKFEVNVAYDGEAGAAEALTGQYAIAVLDVMMPRLNG 60 Query: 61 VDTLRRIRAKSSMPVVMLTAKGDDTDRIIGLELGADDYVPKPCSPREIAARIRAILRRAS 120 VDTLRRIRAKSSMPVVMLTAKGDDTDRIIGLELGADDYVPKPCSPREIAARIRAILRRAS Sbjct: 61 VDTLRRIRAKSSMPVVMLTAKGDDTDRIIGLELGADDYVPKPCSPREIAARIRAILRRAS 120 Query: 121 AENNEQSPYSPLAVGALSMWPEQRRATWNGKPLELTSSEFNLLEVLARNAGKPVSKQHLS 180 AENNEQSPYSPLAVGALSMWPEQRRATWNGKPLELTSSEFNLLEVLARNAGKPVSKQHLS Sbjct: 121 AENNEQSPYSPLAVGALSMWPEQRRATWNGKPLELTSSEFNLLEVLARNAGKPVSKQHLS 180 Query: 181 EQGLGRPLARFDRNIDVHLSSIRQKIAALGSDKSCIQTVYRLGYQFIKE 229 EQGLGRPLARFDRNIDVHLSSIRQKIAALGSDKSCIQTVYRLGYQFIKE Sbjct: 181 EQGLGRPLARFDRNIDVHLSSIRQKIAALGSDKSCIQTVYRLGYQFIKE 229 >E4QNJ2.1 E4QNJ2_METS6 Two component transcriptional regulator, winged helix family Length = 234 Score = 324 bits (831), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 157/229 (68%), Positives = 187/229 (81%), Gaps = 2/229 (0%) Query: 1 MSKVLLIDDDVELVDMLKEYLEQEKFEVNVAYDGEAGAAEALTGQYAIAVLDVMMPRLNG 60 M+KVLLIDDDVELV MLKEYLEQE F+ VAYDGE+GA +AL Y + +LDVMMP++NG Sbjct: 8 MNKVLLIDDDVELVGMLKEYLEQEGFDPTVAYDGESGAEQALRDTYDLILLDVMMPKMNG 67 Query: 61 VDTLRRIRAKSSMPVVMLTAKGDDTDRIIGLELGADDYVPKPCSPREIAARIRAILRRAS 120 +D LR IRA+ + PV+MLTAKG+D DRI+GLELGADDYVPKPC+PREI AR+RAILRR Sbjct: 68 IDALRAIRAEKNTPVLMLTAKGEDADRIVGLELGADDYVPKPCTPREIVARVRAILRRTQ 127 Query: 121 AENNEQSPYSPLAVGALSMWPEQRRATWNGKPLELTSSEFNLLEVLARNAGKPVSKQHLS 180 +N Q + VGAL++WPEQRRA W+G LELTS+EFNLLEVL R+AG+ VSK LS Sbjct: 128 PSDNAQP--VQITVGALTLWPEQRRAEWSGNVLELTSTEFNLLEVLVRHAGRVVSKSDLS 185 Query: 181 EQGLGRPLARFDRNIDVHLSSIRQKIAALGSDKSCIQTVYRLGYQFIKE 229 QGLGRPLARFDR+IDVHLSSIRQKI A + + IQTVYR+GYQ ++E Sbjct: 186 LQGLGRPLARFDRSIDVHLSSIRQKIDAYANGRHYIQTVYRMGYQLVRE 234 >C6XD74.1 C6XD74_METSD Two component transcriptional regulator, winged helix family Length = 227 Score = 324 bits (831), Expect = 6e-87, Method: Compositional matrix adjust. Identities = 157/229 (68%), Positives = 187/229 (81%), Gaps = 2/229 (0%) Query: 1 MSKVLLIDDDVELVDMLKEYLEQEKFEVNVAYDGEAGAAEALTGQYAIAVLDVMMPRLNG 60 M+KVLLIDDDVELV MLKEYLEQE F+ VAYDGE+GA +AL Y + +LDVMMP++NG Sbjct: 1 MNKVLLIDDDVELVGMLKEYLEQEGFDPTVAYDGESGAEQALRDTYDLILLDVMMPKMNG 60 Query: 61 VDTLRRIRAKSSMPVVMLTAKGDDTDRIIGLELGADDYVPKPCSPREIAARIRAILRRAS 120 +D LR IRA+ + PV+MLTAKG+D DRI+GLELGADDYVPKPC+PREI AR+RAILRR Sbjct: 61 IDALRAIRAEKNTPVLMLTAKGEDADRIVGLELGADDYVPKPCTPREIVARVRAILRRTQ 120 Query: 121 AENNEQSPYSPLAVGALSMWPEQRRATWNGKPLELTSSEFNLLEVLARNAGKPVSKQHLS 180 +N Q + VGAL++WPEQRRA W+G LELTS+EFNLLEVL R+AG+ VSK LS Sbjct: 121 PSDNAQP--VQITVGALTLWPEQRRAEWSGNVLELTSTEFNLLEVLVRHAGRVVSKSDLS 178 Query: 181 EQGLGRPLARFDRNIDVHLSSIRQKIAALGSDKSCIQTVYRLGYQFIKE 229 QGLGRPLARFDR+IDVHLSSIRQKI A + + IQTVYR+GYQ ++E Sbjct: 179 LQGLGRPLARFDRSIDVHLSSIRQKIDAYANGRHYIQTVYRMGYQLVRE 227 >Q47I71.1 Q47I71_DECAR Response regulator receiver:Transcriptional regulatory protein, C-terminal Length = 226 Score = 313 bits (801), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 147/229 (64%), Positives = 181/229 (79%), Gaps = 3/229 (1%) Query: 1 MSKVLLIDDDVELVDMLKEYLEQEKFEVNVAYDGEAGAAEALTGQYAIAVLDVMMPRLNG 60 M +LL+DDDVEL ML++YL Q+ FE +DGE+G EAL+G YAI LDVMMP ++G Sbjct: 1 MPHILLVDDDVELSGMLRDYLNQDGFEATAVHDGESGVVEALSGHYAIVALDVMMPGISG 60 Query: 61 VDTLRRIRAKSSMPVVMLTAKGDDTDRIIGLELGADDYVPKPCSPREIAARIRAILRRAS 120 ++ LRRIRA S++PV+MLTAKGDD DRI+GLELGADDYVPKPC PRE+AAR+RAILRR + Sbjct: 61 IEVLRRIRAVSNVPVLMLTAKGDDMDRIVGLELGADDYVPKPCQPRELAARLRAILRRTT 120 Query: 121 AENNEQSPYSPLAVGALSMWPEQRRATWNGKPLELTSSEFNLLEVLARNAGKPVSKQHLS 180 ++ P+ G L+++PEQRR W G P+++TS+EFNL+EVLARNAG+PVSK L Sbjct: 121 L---VEAASGPIVAGPLTVYPEQRRVEWGGAPVDMTSTEFNLVEVLARNAGRPVSKGLLC 177 Query: 181 EQGLGRPLARFDRNIDVHLSSIRQKIAALGSDKSCIQTVYRLGYQFIKE 229 EQ LGRPLARFDR+IDVHLSSIR K+ L +SCIQTVYR GYQ IKE Sbjct: 178 EQALGRPLARFDRSIDVHLSSIRHKLGNLPDGRSCIQTVYRQGYQLIKE 226 >D9SHT0.1 D9SHT0_GALCS Two component transcriptional regulator, winged helix family Length = 234 Score = 313 bits (801), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 154/228 (67%), Positives = 183/228 (80%), Gaps = 1/228 (0%) Query: 2 SKVLLIDDDVELVDMLKEYLEQEKFEVNVAYDGEAGAAEALTGQYAIAVLDVMMPRLNGV 61 +KVLL+DDDVEL ML+ YLE+E FEV +DGE+G EAL G + IAVLDVMMP +G+ Sbjct: 8 TKVLLVDDDVELAGMLRVYLEREGFEVKAVHDGESGITEALQGHHDIAVLDVMMPGKSGI 67 Query: 62 DTLRRIRAKSSMPVVMLTAKGDDTDRIIGLELGADDYVPKPCSPREIAARIRAILRRASA 121 D L +IRA+ +MPV+MLTA+GDD DRIIGLELGADDYVPKPC+PRE+ ARIRAILRR+S Sbjct: 68 DVLVQIRAQGAMPVLMLTARGDDADRIIGLELGADDYVPKPCTPRELTARIRAILRRSSG 127 Query: 122 ENNEQSPYSPLAVGALSMWPEQRRATWNGKPLELTSSEFNLLEVLARNAGKPVSKQHLSE 181 + S + +A G LS+WPEQRRA W GKPLELTS+EFNLLEVLARNAG+ VSK LSE Sbjct: 128 AESALSSSTVIA-GVLSIWPEQRRAEWAGKPLELTSTEFNLLEVLARNAGQVVSKSELSE 186 Query: 182 QGLGRPLARFDRNIDVHLSSIRQKIAALGSDKSCIQTVYRLGYQFIKE 229 Q LGRPLARFDR+IDVHLSSIR+K+ L +S I V+ GYQFI+E Sbjct: 187 QALGRPLARFDRSIDVHLSSIRRKLEPLPDGRSRILAVFNKGYQFIRE 234 >C6WWD2.1 C6WWD2_METML Two component transcriptional regulator, winged helix family Length = 235 Score = 303 bits (777), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 142/228 (62%), Positives = 176/228 (77%) Query: 1 MSKVLLIDDDVELVDMLKEYLEQEKFEVNVAYDGEAGAAEALTGQYAIAVLDVMMPRLNG 60 M K+LLIDDD+EL MLKE+L E F+V A DG +GA AL+ Q+ +AVLDVMMP++NG Sbjct: 1 MHKILLIDDDIELTAMLKEFLCTEGFDVTTASDGVSGAQLALSNQFDLAVLDVMMPKMNG 60 Query: 61 VDTLRRIRAKSSMPVVMLTAKGDDTDRIIGLELGADDYVPKPCSPREIAARIRAILRRAS 120 ++TL IR S +PV+MLTA+GD++DR GLELGADDYVPKPC+PRE+ ARIRAILRRA Sbjct: 61 IETLGLIRKSSQIPVIMLTARGDESDRFFGLELGADDYVPKPCTPRELTARIRAILRRAK 120 Query: 121 AENNEQSPYSPLAVGALSMWPEQRRATWNGKPLELTSSEFNLLEVLARNAGKPVSKQHLS 180 S L VG L++WPEQRR +G + LTS+EFNLLEVLA+NAG VSK+ L+ Sbjct: 121 PTQESLQTESQLTVGDLTIWPEQRRVELDGNTINLTSTEFNLLEVLAKNAGHVVSKKELA 180 Query: 181 EQGLGRPLARFDRNIDVHLSSIRQKIAALGSDKSCIQTVYRLGYQFIK 228 + G+G+PLARFDR+IDVH+SSIRQKI L + CIQTVYR+GYQ IK Sbjct: 181 KLGMGKPLARFDRSIDVHMSSIRQKIGTLKDGRDCIQTVYRMGYQLIK 228 >D7DJ12.1 D7DJ12_METS0 Two component transcriptional regulator, winged helix family Length = 228 Score = 301 bits (770), Expect = 6e-80, Method: Compositional matrix adjust. Identities = 146/228 (64%), Positives = 178/228 (78%), Gaps = 1/228 (0%) Query: 1 MSKVLLIDDDVELVDMLKEYLEQEKFEVNVAYDGEAGAAEALTGQYAIAVLDVMMPRLNG 60 M VLLIDDDVELV+MLKEY+EQE F V VA+DG AGA L + I VLDVMMPRLNG Sbjct: 1 MQTVLLIDDDVELVEMLKEYIEQENFSVQVAHDGIAGAQMLLEQPFDIVVLDVMMPRLNG 60 Query: 61 VDTLRRIRAKSSMPVVMLTAKGDDTDRIIGLELGADDYVPKPCSPREIAARIRAILRRAS 120 ++TL+ IR S++PV+MLTAKGD+TDRI+GLELGADDYVPKP SPRE+ ARIRAILRR Sbjct: 61 IETLKAIRQHSNVPVIMLTAKGDNTDRIVGLELGADDYVPKPSSPRELVARIRAILRRVQ 120 Query: 121 AENNEQSPYSPLAVGALSMWPEQRRATWNGKPLELTSSEFNLLEVLARNAGKPVSKQHLS 180 + + + VGAL +WP QR W+ +P+ LTS+E++LLE+LA+NAG+ VSKQ LS Sbjct: 121 PLETINA-NTQITVGALCIWPAQRLVEWDSQPVILTSTEYSLLEILAKNAGQIVSKQDLS 179 Query: 181 EQGLGRPLARFDRNIDVHLSSIRQKIAALGSDKSCIQTVYRLGYQFIK 228 +Q LGRPLARFDR+IDVHLSSIR K+ L + CIQTV+R GYQ +K Sbjct: 180 QQALGRPLARFDRSIDVHLSSIRHKLGLLPDGRHCIQTVFRSGYQLLK 227 >B9YZ56.1 B9YZ56_9NEIS Two component transcriptional regulator, winged helix family Length = 241 Score = 300 bits (768), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 145/226 (64%), Positives = 178/226 (78%) Query: 3 KVLLIDDDVELVDMLKEYLEQEKFEVNVAYDGEAGAAEALTGQYAIAVLDVMMPRLNGVD 62 KVLL+DDDVEL +ML++YLE+E V +A +G G A AL+G Y + VLDVMMP +NG++ Sbjct: 15 KVLLVDDDVELAEMLRDYLEREGCMVALAANGSDGLALALSGDYHLLVLDVMMPGINGIE 74 Query: 63 TLRRIRAKSSMPVVMLTAKGDDTDRIIGLELGADDYVPKPCSPREIAARIRAILRRASAE 122 LRR+R +S++PV+MLTAKGDD DR++GLELGADDYVPKPC+PRE+ ARIRAILRR + Sbjct: 75 VLRRLRQQSALPVLMLTAKGDDLDRVLGLELGADDYVPKPCTPRELLARIRAILRRGALR 134 Query: 123 NNEQSPYSPLAVGALSMWPEQRRATWNGKPLELTSSEFNLLEVLARNAGKPVSKQHLSEQ 182 Q L GAL+MWP +RRA W+G+PLELTS+EF+LL L R AG PVSK LSE+ Sbjct: 135 EVRQVESDVLREGALAMWPRERRAEWDGRPLELTSTEFSLLAELVRQAGHPVSKGELSER 194 Query: 183 GLGRPLARFDRNIDVHLSSIRQKIAALGSDKSCIQTVYRLGYQFIK 228 LGRPLARFDR+IDVH+SSIRQK+ L +SCIQTV R GYQFIK Sbjct: 195 ALGRPLARFDRSIDVHMSSIRQKLGPLPDGRSCIQTVIRRGYQFIK 240 >C4LC20.1 C4LC20_TOLAT Two component transcriptional regulator, winged helix family Length = 229 Score = 281 bits (718), Expect = 6e-74, Method: Compositional matrix adjust. Identities = 134/229 (58%), Positives = 172/229 (75%) Query: 1 MSKVLLIDDDVELVDMLKEYLEQEKFEVNVAYDGEAGAAEALTGQYAIAVLDVMMPRLNG 60 M ++LL+DDD+EL M +EYL E F V + +DGE G EAL+G Y + +LDVMMP+LNG Sbjct: 1 MIRILLVDDDLELCSMQREYLSNEGFAVQMCHDGERGLEEALSGDYDLILLDVMMPKLNG 60 Query: 61 VDTLRRIRAKSSMPVVMLTAKGDDTDRIIGLELGADDYVPKPCSPREIAARIRAILRRAS 120 +D LRR+R S++PV+MLTAKGDD DRIIGLELGADDYV KPC+PRE+ AR+RAILRRA Sbjct: 61 IDVLRRLRNHSNIPVLMLTAKGDDIDRIIGLELGADDYVSKPCTPRELVARVRAILRRAD 120 Query: 121 AENNEQSPYSPLAVGALSMWPEQRRATWNGKPLELTSSEFNLLEVLARNAGKPVSKQHLS 180 + E PL VGAL++ R ATW + L+LTS+EFNLLE+L R AG+ +SK+ LS Sbjct: 121 PDKQEPGQLQPLRVGALTISAASRNATWRDELLDLTSTEFNLLEILCRRAGRIISKEDLS 180 Query: 181 EQGLGRPLARFDRNIDVHLSSIRQKIAALGSDKSCIQTVYRLGYQFIKE 229 LGRPLAR+DR+IDVH+S++RQK+ L +S IQTV +GYQ + E Sbjct: 181 LHTLGRPLARYDRSIDVHVSNLRQKLGVLKDGRSPIQTVRGIGYQLVVE 229 >D7DQ34.1 D7DQ34_METS0 Two component transcriptional regulator, winged helix family Length = 230 Score = 276 bits (707), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 128/229 (55%), Positives = 169/229 (73%) Query: 1 MSKVLLIDDDVELVDMLKEYLEQEKFEVNVAYDGEAGAAEALTGQYAIAVLDVMMPRLNG 60 M K+LLIDDD+ L +ML++YL E F+V VA DG+ GA L GQ+ + VLDVMMP+LNG Sbjct: 2 MHKILLIDDDIALTEMLEQYLVTEGFDVTVANDGQTGAQYVLAGQFDLTVLDVMMPKLNG 61 Query: 61 VDTLRRIRAKSSMPVVMLTAKGDDTDRIIGLELGADDYVPKPCSPREIAARIRAILRRAS 120 ++TLR IR S +PV+MLTAKGD+++R++GLE GADDYV KPC+PRE+ ARIRA+LRR+ Sbjct: 62 IETLRIIRQASHIPVIMLTAKGDESERVMGLESGADDYVAKPCTPRELLARIRALLRRSK 121 Query: 121 AENNEQSPYSPLAVGALSMWPEQRRATWNGKPLELTSSEFNLLEVLARNAGKPVSKQHLS 180 + + +G L++ P QRR GK + LTS+EFNLLE+LA+NAG V K+ L+ Sbjct: 122 ITKDGSQQALQIVIGGLTITPAQRRVEVAGKAINLTSTEFNLLEILAKNAGHVVCKEDLA 181 Query: 181 EQGLGRPLARFDRNIDVHLSSIRQKIAALGSDKSCIQTVYRLGYQFIKE 229 Q +GR L RFDR++DVH+SSIRQKI + IQTVYR+GYQ I+E Sbjct: 182 LQAMGRTLVRFDRSVDVHMSSIRQKIGTSSNGSDYIQTVYRMGYQLIRE 230