BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0001.p (370 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IUA9.1 D8IUA9_HERSS Nuclease subunit of the excinuclease compl... 635 e-180 D8MRD8.1 D8MRD8_ERWBE Excinuclease cho EC=3.1.25.- 214 1e-53 E3DEM1.1 E3DEM1_ERWSE Nucleotide excision repair endonuclease 209 6e-52 D2TBP7.1 D2TBP7_ERWP6 Putative excinuclease cho EC=3.1.25.- 209 6e-52 D0FSV1.1 D0FSV1_ERWPY Excinuclease cho EC=3.1.25.- 209 6e-52 E1SB35.1 E1SB35_PANVC UvrABC system protein C 206 4e-51 D4GDG0.1 D4GDG0_PANAM Cho 204 2e-50 F2ESX2.1 F2ESX2_PANAN Exconuclease Cho 204 2e-50 E6WCI1.1 E6WCI1_PANSA Excinuclease ABC C subunit domain protein 203 3e-50 C6UW82.1 C6UW82_ECO5T Endonuclease of nucleotide excision repair 201 1e-49 >D8IUA9.1 D8IUA9_HERSS Nuclease subunit of the excinuclease complex protein EC=3.1.25.- Length = 317 Score = 635 bits (1639), Expect = e-180, Method: Compositional matrix adjust. Identities = 313/317 (98%), Positives = 315/317 (99%) Query: 54 VQEGEHGLPALPSLPPRGLPLATFNAPQPAAHRAATFSYPLHIDRASIEALPSACGVYIL 113 +QEGEHGLPALPS PPRGLPLATFNAPQPAAHRAATFSYPLHIDRASIEALPSACGVYIL Sbjct: 1 MQEGEHGLPALPSFPPRGLPLATFNAPQPAAHRAATFSYPLHIDRASIEALPSACGVYIL 60 Query: 114 RGEGDQALYVGRSVNLRSRVLAHLHHAEDQFLIGRTRRIECLRTAGELGAALLENSLLRD 173 RGEGDQALYVGRSVNLRSRVLAHLHHAEDQFLIGRTRRIECLRTAGELGAALLENSLLRD Sbjct: 61 RGEGDQALYVGRSVNLRSRVLAHLHHAEDQFLIGRTRRIECLRTAGELGAALLENSLLRD 120 Query: 174 LRPAHNKKQRAKRSLFTLRLDEQGQPLVAQVADHEFNRAGKLFGLYTSERAAQEALHKLV 233 LRPAHNKKQRAKR LFTLRLDEQGQPLVAQVADHEFNRAGKLFGLYTSERAAQEALHKLV Sbjct: 121 LRPAHNKKQRAKRGLFTLRLDEQGQPLVAQVADHEFNRAGKLFGLYTSERAAQEALHKLV 180 Query: 234 EHHGLCSIATGLEQGEGPGMACFGRQIRRCRGACTGEESHEQHQSRLLQALEDLRILPWP 293 EHHGLCSIATGLEQGEGPGMACFGRQIRRCRGACTGEESHEQHQSRLLQALEDLRILPWP Sbjct: 181 EHHGLCSIATGLEQGEGPGMACFGRQIRRCRGACTGEESHEQHQSRLLQALEDLRILPWP 240 Query: 294 YAGPMGIVEQGDGWQQIHVIDQWRYLGSLDRQQRRLPARPAASLKGFDLDTYKLVIQPYL 353 YAGPMGIVEQGDGWQQIHVIDQWRYLGSLDRQQRRLPARPAASLKGFDLDTYKLVIQPYL Sbjct: 241 YAGPMGIVEQGDGWQQIHVIDQWRYLGSLDRQQRRLPARPAASLKGFDLDTYKLVIQPYL 300 Query: 354 LGQLELRPLPGLPLAHP 370 LGQLELRPLPGLPLA+P Sbjct: 301 LGQLELRPLPGLPLAYP 317 >D8MRD8.1 D8MRD8_ERWBE Excinuclease cho EC=3.1.25.- Length = 287 Score = 214 bits (546), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 122/289 (42%), Positives = 174/289 (60%), Gaps = 15/289 (5%) Query: 83 AAHR-----AATFSYPLHIDRASIEALPSACGVYILRGEGDQA-LYVGRSVNLRSRVLAH 136 A+HR AA + YP H+ R +E LPS GVY+ GE + LY+G+SVNLRSRV++H Sbjct: 6 ASHRLEFEPAAIYQYPDHL-RPYLEGLPSLPGVYVFHGESETMPLYIGKSVNLRSRVMSH 64 Query: 137 LHHAEDQFLIGRTRRIECLRTAGELGAALLENSLLRDLRPAHNKKQRAKRSLFTLRLDEQ 196 A++ ++ + +R+ + TAGELGA LLE +++ +P NK+ R R L +L + + Sbjct: 65 FRTADEAKMLRQAKRVTFIPTAGELGALLLEAQMIKVQQPLFNKRLRKNRQLCSLHMAGE 124 Query: 197 GQPLVAQVADHEFNRAGKLFGLYTSERAAQEALHKLVEHHGLCSIATGLEQGEGPGMACF 256 +P V D +F+ LFGLY S AA E L K+ + LC GLE+ G ACF Sbjct: 125 -KPTVVYAKDLDFSHTPDLFGLYASRHAALEKLQKIADEQRLCLGVLGLEK-LSKGRACF 182 Query: 257 GRQIRRCRGACTGEESHEQHQSRLLQALEDLRILPWPYAGPMGIVEQGDGWQQIHVIDQW 316 + RC GAC G+ES ++HQ RL+ ALE +R+ WP+ G +G+VEQG QQIH+I+ W Sbjct: 183 RASLGRCAGACCGKESLDEHQQRLIAALERVRVQCWPWQGAVGVVEQGINHQQIHIINNW 242 Query: 317 RYLGSLDR--QQRRLPARPAASLKGFDLDTYKLVIQPYLLGQLELRPLP 363 YLGS++ Q L P +GFD D YK++ +P L G+ + PLP Sbjct: 243 FYLGSVEDLAQASELTTTP----QGFDSDGYKILCKPILSGKFPILPLP 287 >E3DEM1.1 E3DEM1_ERWSE Nucleotide excision repair endonuclease Length = 289 Score = 209 bits (532), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 118/291 (40%), Positives = 171/291 (58%), Gaps = 13/291 (4%) Query: 73 PLATFNAPQPAAHRAATFSYPLHIDRASIEALPSACGVYILRGEGDQA-LYVGRSVNLRS 131 P A F+A A + YP H+ R +EALP GVY+ G+ + LY+G+SVN+RS Sbjct: 8 PRAEFDA-------TAIYQYPEHL-RPWLEALPKLPGVYVFHGDSETMPLYIGKSVNIRS 59 Query: 132 RVLAHLHHAEDQFLIGRTRRIECLRTAGELGAALLENSLLRDLRPAHNKKQRAKRSLFTL 191 RVL+HL A++ ++ + RI + TAGELGA LLE +++ +P NK+ R R L L Sbjct: 60 RVLSHLRTADEARMLRQATRISFMTTAGELGALLLEARMIKLQQPLFNKRLRKNRQLCAL 119 Query: 192 RLDEQGQPLVAQVADHEFNRAGKLFGLYTSERAAQEALHKLVEHHGLCSIATGLEQGEGP 251 ++ E G PLV D +F+ L+GLY + RAA E L K+ + LC GLE+ Sbjct: 120 QIAE-GSPLVVYAKDVDFSSTSGLYGLYANRRAALETLQKIADEQRLCYYLLGLEKMRS- 177 Query: 252 GMACFGRQIRRCRGACTGEESHEQHQSRLLQALEDLRILPWPYAGPMGIVEQGDGWQQIH 311 G ACF + RC GAC G+E+ +HQ RLL ALE +R+ WP+ + ++EQ G Q H Sbjct: 178 GNACFRFALNRCAGACCGKETRAEHQQRLLSALEAVRLRCWPWPDAVAVLEQRTGQTQYH 237 Query: 312 VIDQWRYLGSLDRQQRRLPARPAASLKGFDLDTYKLVIQPYLLGQLELRPL 362 +I+ W YLGS+ + + A ++ GFD D YK++ +P L G+L + PL Sbjct: 238 IINNWLYLGSVSKLEE--AAGLCSTTPGFDSDGYKILCKPMLAGKLPIVPL 286 >D2TBP7.1 D2TBP7_ERWP6 Putative excinuclease cho EC=3.1.25.- Length = 289 Score = 209 bits (532), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 118/291 (40%), Positives = 171/291 (58%), Gaps = 13/291 (4%) Query: 73 PLATFNAPQPAAHRAATFSYPLHIDRASIEALPSACGVYILRGEGDQA-LYVGRSVNLRS 131 P A F+A A + YP H+ R +EALP GVY+ G+ + LY+G+SVN+RS Sbjct: 8 PRAEFDA-------TAIYQYPEHL-RPWLEALPKLPGVYVFHGDSETMPLYIGKSVNIRS 59 Query: 132 RVLAHLHHAEDQFLIGRTRRIECLRTAGELGAALLENSLLRDLRPAHNKKQRAKRSLFTL 191 RVL+HL A++ ++ + RI + TAGELGA LLE +++ +P NK+ R R L L Sbjct: 60 RVLSHLRTADEARMLRQATRISFMTTAGELGALLLEARMIKLQQPLFNKRLRKNRQLCAL 119 Query: 192 RLDEQGQPLVAQVADHEFNRAGKLFGLYTSERAAQEALHKLVEHHGLCSIATGLEQGEGP 251 ++ E G PLV D +F+ L+GLY + RAA E L K+ + LC GLE+ Sbjct: 120 QIAE-GSPLVVYAKDVDFSSTSGLYGLYANRRAALETLQKIADEQRLCYYLLGLEKMRS- 177 Query: 252 GMACFGRQIRRCRGACTGEESHEQHQSRLLQALEDLRILPWPYAGPMGIVEQGDGWQQIH 311 G ACF + RC GAC G+E+ +HQ RLL ALE +R+ WP+ + ++EQ G Q H Sbjct: 178 GNACFRFALNRCAGACCGKETRAEHQQRLLSALEAVRLRCWPWPDAVAVLEQRTGQTQYH 237 Query: 312 VIDQWRYLGSLDRQQRRLPARPAASLKGFDLDTYKLVIQPYLLGQLELRPL 362 +I+ W YLGS+ + + A ++ GFD D YK++ +P L G+L + PL Sbjct: 238 IINNWLYLGSVSKLEE--AAGLCSTTPGFDSDGYKILCKPMLAGKLPIVPL 286 >D0FSV1.1 D0FSV1_ERWPY Excinuclease cho EC=3.1.25.- Length = 289 Score = 209 bits (532), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 118/291 (40%), Positives = 171/291 (58%), Gaps = 13/291 (4%) Query: 73 PLATFNAPQPAAHRAATFSYPLHIDRASIEALPSACGVYILRGEGDQA-LYVGRSVNLRS 131 P A F+A A + YP H+ R +EALP GVY+ G+ + LY+G+SVN+RS Sbjct: 8 PRAEFDA-------TAIYQYPEHL-RPWLEALPKLPGVYVFHGDSETMPLYIGKSVNIRS 59 Query: 132 RVLAHLHHAEDQFLIGRTRRIECLRTAGELGAALLENSLLRDLRPAHNKKQRAKRSLFTL 191 RVL+HL A++ ++ + RI + TAGELGA LLE +++ +P NK+ R R L L Sbjct: 60 RVLSHLRTADEARMLRQATRISFMTTAGELGALLLEARMIKLQQPLFNKRLRKNRQLCAL 119 Query: 192 RLDEQGQPLVAQVADHEFNRAGKLFGLYTSERAAQEALHKLVEHHGLCSIATGLEQGEGP 251 ++ E G PLV D +F+ L+GLY + RAA E L K+ + LC GLE+ Sbjct: 120 QIAE-GSPLVVYAKDVDFSSTSGLYGLYANRRAALETLQKIADEQRLCYYLLGLEKMRS- 177 Query: 252 GMACFGRQIRRCRGACTGEESHEQHQSRLLQALEDLRILPWPYAGPMGIVEQGDGWQQIH 311 G ACF + RC GAC G+E+ +HQ RLL ALE +R+ WP+ + ++EQ G Q H Sbjct: 178 GNACFRFALNRCAGACCGKETRAEHQQRLLSALEAVRLRCWPWPDAVAVLEQRTGQTQYH 237 Query: 312 VIDQWRYLGSLDRQQRRLPARPAASLKGFDLDTYKLVIQPYLLGQLELRPL 362 +I+ W YLGS+ + + A ++ GFD D YK++ +P L G+L + PL Sbjct: 238 IINNWLYLGSVSKLEE--AAGLCSTTPGFDSDGYKILCKPMLAGKLPIVPL 286 >E1SB35.1 E1SB35_PANVC UvrABC system protein C Length = 286 Score = 206 bits (524), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 118/285 (41%), Positives = 170/285 (59%), Gaps = 10/285 (3%) Query: 80 PQPAAHRAATFSYPLHIDRASIEALPSACGVYILRGEGDQA-LYVGRSVNLRSRVLAHLH 138 P+P A+ + YP H+ R +E LP+ GVY GE + LY+G+SVNLRSRV++H Sbjct: 10 PEPDAN--TIYQYPEHL-REWLEGLPNHPGVYTFHGESESLPLYIGKSVNLRSRVMSHFR 66 Query: 139 HAEDQFLIGRTRRIECLRTAGELGAALLENSLLRDLRPAHNKKQRAKRSLFTLRLDEQGQ 198 ++ ++ ++RR+ + TAG+LGA LLE +++ +P NK+ R R L +L++ + G+ Sbjct: 67 TPDEAKMLRQSRRVSWIPTAGDLGALLLEAQMIKTQQPLFNKRLRKNRQLCSLQITD-GK 125 Query: 199 PLVAQVADHEFNRAGKLFGLYTSERAAQEALHKLVEHHGLCSIATGLEQGEGPGMACFGR 258 P V D +F+++ LFGLY S AA E L +L + LC GLE G CF Sbjct: 126 PNVVYAKDLDFSQSPNLFGLYRSRFAALERLKQLANEYQLCHGLLGLE-ALSAGRGCFRS 184 Query: 259 QIRRCRGACTGEESHEQHQSRLLQALEDLRILPWPYAGPMGIVEQGDGWQQIHVIDQWRY 318 +RRC GAC G+E HQ RLL+ALE++R+ WP+ G +G+VE+G QIHVID W Y Sbjct: 185 ALRRCAGACCGKEPVSDHQDRLLEALENVRVFCWPWQGAVGLVEEGKEMTQIHVIDHWFY 244 Query: 319 LGSLDR-QQRRLPARPAASLKGFDLDTYKLVIQPYLLGQLELRPL 362 LGS+ + R RP GFD D YK++ +P L G + PL Sbjct: 245 LGSVSSMDEARKLQRPKG---GFDHDGYKILCRPILSGAYPILPL 286 >D4GDG0.1 D4GDG0_PANAM Cho Length = 287 Score = 204 bits (519), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 117/290 (40%), Positives = 167/290 (57%), Gaps = 18/290 (6%) Query: 83 AAHR-----AATFSYPLHIDRASIEALPSACGVYILRGEGDQA-LYVGRSVNLRSRVLAH 136 A HR A + YP H+ R +E LP+ GVY G+ + LY+G+SVNLRSRV++H Sbjct: 6 ATHRLEFDAATIYEYPEHL-REWLEGLPNQPGVYTFHGDSETLPLYIGKSVNLRSRVMSH 64 Query: 137 LHHAEDQFLIGRTRRIECLRTAGELGAALLENSLLRDLRPAHNKKQRAKRSLFTLRLDEQ 196 ++ ++ ++RR+ + TAG+LGA LLE +++ +P NK+ R R L +LR+ + Sbjct: 65 FRTPDEAKMLRQSRRVSWIPTAGDLGALLLEAQMIKTQQPLFNKRLRKNRQLCSLRITPE 124 Query: 197 GQPLVAQVADHEFNRAGKLFGLYTSERAAQEALHKLVEHHGLCSIATGLEQGEGPGMACF 256 G+P V D +F+++ LFGLY S AA E L +L + + LC GLE CF Sbjct: 125 GKPDVVYARDVDFSQSPNLFGLYRSRFAALERLKQLADEYQLCHGLLGLE-AVSASRGCF 183 Query: 257 GRQIRRCRGACTGEESHEQHQSRLLQALEDLRILPWPYAGPMGIVEQGDGWQQIHVIDQW 316 +RRC GAC G+E HQ RLL ALE +R+ WP+ G + +VE+G QIHVID W Sbjct: 184 RSALRRCAGACCGKEPVSDHQDRLLSALESVRVFCWPWQGAVALVEEGKHMTQIHVIDHW 243 Query: 317 RYLGSLDRQQRRLPARPAASLK----GFDLDTYKLVIQPYLLGQLELRPL 362 YLGS++ + A +LK GFD D YK++ P L G + PL Sbjct: 244 FYLGSVNTIEE------AKALKRGKGGFDHDGYKILCSPVLSGNYPVIPL 287 >F2ESX2.1 F2ESX2_PANAN Exconuclease Cho Length = 287 Score = 204 bits (518), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 117/290 (40%), Positives = 167/290 (57%), Gaps = 18/290 (6%) Query: 83 AAHR-----AATFSYPLHIDRASIEALPSACGVYILRGEGDQA-LYVGRSVNLRSRVLAH 136 A HR A + YP H+ R +E LP+ GVY G+ + LY+G+SVNLRSRV++H Sbjct: 6 ATHRLEFDAATIYEYPEHL-REWLEGLPNQPGVYTFHGDSETLPLYIGKSVNLRSRVMSH 64 Query: 137 LHHAEDQFLIGRTRRIECLRTAGELGAALLENSLLRDLRPAHNKKQRAKRSLFTLRLDEQ 196 ++ ++ ++RR+ + TAG+LGA LLE +++ +P NK+ R R L +LR+ + Sbjct: 65 FRTPDEAKMLRQSRRVSWIPTAGDLGALLLEAQMIKTQQPLFNKRLRKNRQLCSLRITPE 124 Query: 197 GQPLVAQVADHEFNRAGKLFGLYTSERAAQEALHKLVEHHGLCSIATGLEQGEGPGMACF 256 G+P V D +F+++ LFGLY S AA E L +L + + LC GLE CF Sbjct: 125 GKPDVVYARDVDFSQSPNLFGLYRSRFAALERLKQLADEYQLCHGLLGLE-AVSASRGCF 183 Query: 257 GRQIRRCRGACTGEESHEQHQSRLLQALEDLRILPWPYAGPMGIVEQGDGWQQIHVIDQW 316 +RRC GAC G+E HQ RLL ALE +R+ WP+ G + +VE+G QIHVID W Sbjct: 184 RSALRRCAGACCGKEPVSDHQDRLLSALESVRVFCWPWQGAVALVEEGKHMTQIHVIDHW 243 Query: 317 RYLGSLDRQQRRLPARPAASLK----GFDLDTYKLVIQPYLLGQLELRPL 362 YLGS++ + A +LK GFD D YK++ P L G + PL Sbjct: 244 FYLGSVNTIEE------AKALKRGNGGFDHDGYKILCSPVLSGNYPVIPL 287 >E6WCI1.1 E6WCI1_PANSA Excinuclease ABC C subunit domain protein Length = 286 Score = 203 bits (517), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 117/279 (41%), Positives = 164/279 (58%), Gaps = 16/279 (5%) Query: 87 AATFSYPLHIDRASIEALPSACGVYILRGEGDQA-LYVGRSVNLRSRVLAHLHHAEDQFL 145 AA + YP H+ R +E LP+ GVY+ GE D LY+G+SVNLRSRV++H ++ + Sbjct: 15 AAIYQYPEHL-RQWLEGLPNQPGVYVFHGESDNLPLYIGKSVNLRSRVMSHFRTPDEASM 73 Query: 146 IGRTRRIECLRTAGELGAALLENSLLRDLRPAHNKKQRAKRSLFTLRLDEQGQPLVAQVA 205 + + RRI + TAG+LGA LLE +++ +P NK+ R R L +L+L++ P V Sbjct: 74 LRQARRISWIPTAGDLGAQLLEAQMIKTQQPLFNKRLRKNRQLCSLQLNDT-VPQVVYAR 132 Query: 206 DHEFNRAGKLFGLYTSERAAQEALHKLVEHHGLCSIATGLEQGEGPGMACFGRQIRRCRG 265 D +F+R L+GL+ S AA E L + + LC GLE G CF ++RC G Sbjct: 133 DLDFSRTANLYGLFRSRHAALEKLKSIADEQRLCHGLLGLENLRS-GRGCFRAALKRCAG 191 Query: 266 ACTGEESHEQHQSRLLQALEDLRILPWPYAGPMGIVEQGDGWQQIHVIDQWRYLGSLD-- 323 AC G E E HQ RL QAL+ LR++ WP++G +G+VE+G QIHVID W +LGS+ Sbjct: 192 ACCGNEPPEAHQQRLQQALDALRVVCWPWSGAVGMVERGATMTQIHVIDHWFWLGSVSSE 251 Query: 324 ---RQQRRLPARPAASLKGFDLDTYKLVIQPYLLGQLEL 359 RQ RR P GFD D YK++ +P L G+ L Sbjct: 252 AEARQLRRNP-------HGFDHDGYKILCRPLLSGEFPL 283 >C6UW82.1 C6UW82_ECO5T Endonuclease of nucleotide excision repair Length = 295 Score = 201 bits (511), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 116/292 (39%), Positives = 173/292 (59%), Gaps = 16/292 (5%) Query: 77 FNAPQPAAHRAATFSYPLHIDRASIEALPSACGVYILRGEGDQA-LYVGRSVNLRSRVLA 135 +P+ AA + YP H+ R+ + LP+ GVY+ GE D LY+G+SVN+RSRVL+ Sbjct: 5 LTSPRLEFEAAAIYEYPEHL-RSFLNDLPTRPGVYLFHGESDTMPLYIGKSVNIRSRVLS 63 Query: 136 HLHHAEDQFLIGRTRRIECLRTAGELGAALLENSLLRDLRPAHNKKQRAKRSLFTLRLDE 195 HL ++ ++ ++RRI + TAGE+GA LLE L+++ +P NK+ R R L L+L+E Sbjct: 64 HLRTPDEAAMLRQSRRISWICTAGEIGALLLEARLIKEQQPLFNKRLRRNRQLCALQLNE 123 Query: 196 QGQPLVAQVADHEFNRAGKLFGLYTSERAAQEALHKLVEHHGLCSIATGLEQGEGPGMAC 255 + +V + +F+RA LFGL+ + RAA +AL + + LC GLE G AC Sbjct: 124 KRVDVV-YAKEVDFSRAPNLFGLFANRRAALQALQSIADEQKLCYGLLGLEPL-SRGRAC 181 Query: 256 FGRQIRRCRGACTGEESHEQHQSRLLQALEDLRILPWPYAGPMGIVEQGDGWQQIHVIDQ 315 F ++RC GAC G+ESHE+H RL Q+LE LR++ WP+ G + + EQ Q H+I Sbjct: 182 FRSALKRCAGACCGKESHEEHALRLRQSLERLRVVCWPWQGAVALKEQHPEMTQYHIIQN 241 Query: 316 WRYLGSLDRQQR-----RLPARPAASLKGFDLDTYKLVIQPYLLGQLELRPL 362 W +LG+++ Q+ R PA GFD D YK++ +P L G E+ L Sbjct: 242 WLWLGAVNSQEEATTLIRTPA-------GFDHDGYKILCKPLLSGNYEITEL 286