BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0026.0035.p (316 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IRZ7.1 D8IRZ7_HERSS D-2-hydroxyacid dehydrogenase protein EC=1... 635 e-180 Q126V3.1 Q126V3_POLSJ D-isomer specific 2-hydroxyacid dehydrogen... 368 e-100 A7MPZ4.1 A7MPZ4_ENTS8 Putative uncharacterized protein 349 3e-94 C9Y3Z7.1 C9Y3Z7_CROTZ Glyoxylate reductase EC=1.1.1.215 EC=1.1.1... 348 7e-94 C1DMD1.1 C1DMD1_AZOVD 2-hydroxyacid dehydrogenase 336 2e-90 E1HS99.1 E1HS99_ECOLX Putative glyoxylate reductase 333 2e-89 C4UWY3.1 C4UWY3_YERRO D-isomer specific 2-hydroxyacid dehydrogenase 330 2e-88 D8MLQ8.1 D8MLQ8_ERWBE D-isomer specific 2-hydroxyacid dehydrogen... 328 9e-88 E8XUR9.1 E8XUR9_RAHSY D-isomer specific 2-hydroxyacid dehydrogen... 318 7e-85 B1LXK8.1 B1LXK8_METRJ D-isomer specific 2-hydroxyacid dehydrogen... 316 4e-84 >D8IRZ7.1 D8IRZ7_HERSS D-2-hydroxyacid dehydrogenase protein EC=1.1.99.6 Length = 316 Score = 635 bits (1637), Expect = e-180, Method: Compositional matrix adjust. Identities = 315/316 (99%), Positives = 316/316 (100%) Query: 1 MTTNNRPHVLIVARLPQHLLDLLQQHYTCHNLILQPHSEAELAAIAPQIRGIAANGEAKV 60 MTTNNRPHVLIVARLPQHLLDLLQQHYTCHNLILQPHSEAELAAIAPQIRGIAANGEAKV Sbjct: 1 MTTNNRPHVLIVARLPQHLLDLLQQHYTCHNLILQPHSEAELAAIAPQIRGIAANGEAKV 60 Query: 61 SREFMARFPALEIVSVFGVGYDGVDVPAARERGIHVTHTPDVLNDDVADLAIALMLATAR 120 SREFMARFPALEIVSVFGVGYDGVDVPAARERGIHVTHTPDVLNDDVADLA+ALMLATAR Sbjct: 61 SREFMARFPALEIVSVFGVGYDGVDVPAARERGIHVTHTPDVLNDDVADLAMALMLATAR 120 Query: 121 NVVRADRFARSGEWKKGPFPFTTKVSGARLGIVGLGRIGQAIAKRAAAFDMQISYHNRSR 180 NVVRADRFARSGEWKKGPFPFTTKVSGARLGIVGLGRIGQAIAKRAAAFDMQISYHNRSR Sbjct: 121 NVVRADRFARSGEWKKGPFPFTTKVSGARLGIVGLGRIGQAIAKRAAAFDMQISYHNRSR 180 Query: 181 KDVPYTYVDSITALAREVDFLVMITPGGAGTRALVNAEVLEALGPKGFLINVARGSVVDE 240 KDVPYTYVDSITALAREVDFLVMITPGGAGTRALVNAEVLEALGPKGFLINVARGSVVDE Sbjct: 181 KDVPYTYVDSITALAREVDFLVMITPGGAGTRALVNAEVLEALGPKGFLINVARGSVVDE 240 Query: 241 AALIAALKTGVIAGAGLDVFADEPNVPAELAALDNVVLTPHMASGTLVTRTAMADLAFNN 300 AALIAALKTGVIAGAGLDVFADEPNVPAELAALDNVVLTPHMASGTLVTRTAMADLAFNN Sbjct: 241 AALIAALKTGVIAGAGLDVFADEPNVPAELAALDNVVLTPHMASGTLVTRTAMADLAFNN 300 Query: 301 LQAHFSGAGVISPVPD 316 LQAHFSGAGVISPVPD Sbjct: 301 LQAHFSGAGVISPVPD 316 >Q126V3.1 Q126V3_POLSJ D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein Length = 315 Score = 368 bits (944), Expect = e-100, Method: Compositional matrix adjust. Identities = 190/313 (60%), Positives = 235/313 (75%), Gaps = 2/313 (0%) Query: 5 NRPHVLIVARLPQHLLDLLQQHYTCHNLILQPHSEAELAAIAPQIRGIAANGEAKVSREF 64 ++P +L VA+LP +L++ L++ + H I Q A AA + +GE+KV R Sbjct: 2 SKPEILAVAKLPPYLIEPLREIFVVHEQIHQTDPAAFAAAAGRIRAIVG-SGESKVPRSL 60 Query: 65 MARFPALEIVSVFGVGYDGVDVPAARERGIHVTHTPDVLNDDVADLAIALMLATARNVVR 124 MA+ PALE++S+ GVGYDGVDV AA ER I VTHTP VLNDDVADLAI LML+ AR + + Sbjct: 61 MAQLPALEMISIMGVGYDGVDVTAALERNIRVTHTPGVLNDDVADLAIGLMLSVARRIPQ 120 Query: 125 ADRFARSGEWKKGPFPFTTKVSGARLGIVGLGRIGQAIAKRAAAFDMQISYHNRSRK-DV 183 AD++ RSG W +GP P KVSG RLGIVGLGRIGQAIA RA AF M ++Y RSRK ++ Sbjct: 121 ADQYVRSGRWPEGPMPLARKVSGERLGIVGLGRIGQAIATRAEAFGMSVAYTARSRKAEL 180 Query: 184 PYTYVDSITALAREVDFLVMITPGGAGTRALVNAEVLEALGPKGFLINVARGSVVDEAAL 243 PY Y S ALA EVDFLV+ITPGGAGTR L+NA+VL+ALGP+G+LINVARGSVVDEAAL Sbjct: 181 PYAYYPSAQALAAEVDFLVLITPGGAGTRKLINADVLKALGPQGYLINVARGSVVDEAAL 240 Query: 244 IAALKTGVIAGAGLDVFADEPNVPAELAALDNVVLTPHMASGTLVTRTAMADLAFNNLQA 303 + AL+ GVIAGA LDVF +EP VP+ L LDNVVL PH+ S T TR AMADLA +NL+A Sbjct: 241 VEALQQGVIAGAALDVFENEPVVPSALWTLDNVVLAPHIGSATRQTRGAMADLAASNLRA 300 Query: 304 HFSGAGVISPVPD 316 HF+G +++PVP+ Sbjct: 301 HFAGEPLLTPVPE 313 >A7MPZ4.1 A7MPZ4_ENTS8 Putative uncharacterized protein Length = 310 Score = 349 bits (895), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 184/311 (59%), Positives = 220/311 (70%), Gaps = 3/311 (0%) Query: 6 RPHVLIVARLPQHLLDLLQQHYTCHNLILQPHSEAELAAIAPQIRGIAANGEAKVSREFM 65 +P VL A LP L L++ Y S+A+ AIA I + NGEA V+ EF+ Sbjct: 2 KPMVLKHAYLPDALTAELRERYDLREF--SQMSDADFGAIAGDITALVTNGEAVVTGEFI 59 Query: 66 ARFPALEIVSVFGVGYDGVDVPAARERGIHVTHTPDVLNDDVADLAIALMLATARNVVRA 125 AR PAL +++VFGVGYDGVDV AARERGI VTHTP VL DDVADLAI LMLAT+R +V A Sbjct: 60 ARLPALSLIAVFGVGYDGVDVAAARERGIAVTHTPGVLTDDVADLAIGLMLATSRRIVAA 119 Query: 126 DRFARSGEWKKGPFPFTTKVSGARLGIVGLGRIGQAIAKRAAAFDMQISYHNRS-RKDVP 184 +F G W++G F ++ KVSGARLGI G+GRIGQAIA+RA AFDM+I Y R +P Sbjct: 120 QKFIEQGGWQQGGFTWSRKVSGARLGIFGMGRIGQAIARRAQAFDMEIRYTGRQPHSALP 179 Query: 185 YTYVDSITALAREVDFLVMITPGGAGTRALVNAEVLEALGPKGFLINVARGSVVDEAALI 244 Y +V + LARE DFL++ PGG TR +VNA VLEALGP+G LINVARGSVVDE ALI Sbjct: 180 YRFVPGLAQLARESDFLMLCAPGGDATRGVVNAAVLEALGPQGILINVARGSVVDETALI 239 Query: 245 AALKTGVIAGAGLDVFADEPNVPAELAALDNVVLTPHMASGTLVTRTAMADLAFNNLQAH 304 AAL++G IAGAGLDVF DEPNVPA L DNVV+TPHMAS T TR M+ L N+ A Sbjct: 240 AALESGKIAGAGLDVFTDEPNVPAPLQQRDNVVITPHMASATWETRREMSRLVLENINAW 299 Query: 305 FSGAGVISPVP 315 +G +I+PVP Sbjct: 300 CAGEPLITPVP 310 >C9Y3Z7.1 C9Y3Z7_CROTZ Glyoxylate reductase EC=1.1.1.215 EC=1.1.1.26 EC=1.1.1.81 EC=1.1.1.95 Length = 310 Score = 348 bits (892), Expect = 7e-94, Method: Compositional matrix adjust. Identities = 183/311 (58%), Positives = 220/311 (70%), Gaps = 3/311 (0%) Query: 6 RPHVLIVARLPQHLLDLLQQHYTCHNLILQPHSEAELAAIAPQIRGIAANGEAKVSREFM 65 +P VL A LP L L++ Y S+A++ AIA I + NGEA V+R F+ Sbjct: 2 KPIVLKHAYLPDALTVELRERYDLREF--SQMSDADVEAIAGDITALVTNGEAVVTRAFI 59 Query: 66 ARFPALEIVSVFGVGYDGVDVPAARERGIHVTHTPDVLNDDVADLAIALMLATARNVVRA 125 R PAL +++VFGVGYDGVDV AARERGI VTHTP VL DDVADLAI LMLAT+R +V A Sbjct: 60 TRLPALSLIAVFGVGYDGVDVAAARERGIAVTHTPGVLTDDVADLAIGLMLATSRRIVAA 119 Query: 126 DRFARSGEWKKGPFPFTTKVSGARLGIVGLGRIGQAIAKRAAAFDMQISYHNRS-RKDVP 184 +F G W++G F +T KVSGARLGI G+GRIGQAIA+RA AFDM ISY R R +P Sbjct: 120 QKFIEQGGWQQGGFTWTRKVSGARLGIFGMGRIGQAIARRAQAFDMAISYTGRQPRSALP 179 Query: 185 YTYVDSITALAREVDFLVMITPGGAGTRALVNAEVLEALGPKGFLINVARGSVVDEAALI 244 Y +V + LA+E DFL++ PGG TR +VNA VLEALGP+G LIN+ARGSVV+E ALI Sbjct: 180 YRFVPDLQQLAQESDFLMLCAPGGDATRGVVNAAVLEALGPQGILINIARGSVVNETALI 239 Query: 245 AALKTGVIAGAGLDVFADEPNVPAELAALDNVVLTPHMASGTLVTRTAMADLAFNNLQAH 304 AAL+ G IAGAGLDVF DEPNVPA L DNVV+TPHMAS T TR M+ L N+ A Sbjct: 240 AALERGAIAGAGLDVFTDEPNVPAALQQRDNVVITPHMASATWETRREMSRLVLENVNAW 299 Query: 305 FSGAGVISPVP 315 +G +I+PVP Sbjct: 300 CTGEPLITPVP 310 >C1DMD1.1 C1DMD1_AZOVD 2-hydroxyacid dehydrogenase Length = 318 Score = 336 bits (862), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 188/311 (60%), Positives = 219/311 (70%), Gaps = 5/311 (1%) Query: 6 RPHVLIVARLPQHLLDLLQQH-YTCHNLILQPHSEAELAAIAPQIRGIAANGEAKVSREF 64 +P+VL +ARLP DLL + Y + ++ S AEL A A +R + ANGE++VSRE Sbjct: 2 KPNVLKIARLP----DLLSERLYADYRVLEGSESGAELGAAAADVRALVANGESRVSREL 57 Query: 65 MARFPALEIVSVFGVGYDGVDVPAARERGIHVTHTPDVLNDDVADLAIALMLATARNVVR 124 + R PALEI+ VFGVGYDGVDV AA RGI VTHTPDVL DDVAD A+ L+L AR V Sbjct: 58 LDRLPALEIIVVFGVGYDGVDVRAAEARGIPVTHTPDVLTDDVADFAMTLLLGIARRVAV 117 Query: 125 ADRFARSGEWKKGPFPFTTKVSGARLGIVGLGRIGQAIAKRAAAFDMQISYHNRSRKDVP 184 ADRF R G W GPFPFT KVSGARLGIVGLGRIG AIA+RA AFDM I+Y R + V Sbjct: 118 ADRFVREGAWAGGPFPFTRKVSGARLGIVGLGRIGSAIARRATAFDMLIAYCGRRPRPVD 177 Query: 185 YTYVDSITALAREVDFLVMITPGGAGTRALVNAEVLEALGPKGFLINVARGSVVDEAALI 244 Y Y S+ LA +VDFLV+ GGA TR L++A VL+ALGP+G L+NV RGSVVDEAAL Sbjct: 178 YRYFASVHELAAQVDFLVVSANGGADTRHLIDASVLDALGPEGILVNVGRGSVVDEAALA 237 Query: 245 AALKTGVIAGAGLDVFADEPNVPAELAALDNVVLTPHMASGTLVTRTAMADLAFNNLQAH 304 AL + GA LDVF DEP V L LDNV+LTPHMAS T TR AMADL NL+AH Sbjct: 238 GALAERRLLGAALDVFEDEPRVHPRLLELDNVLLTPHMASATWATRRAMADLLMANLRAH 297 Query: 305 FSGAGVISPVP 315 F+G + SPVP Sbjct: 298 FAGQPLPSPVP 308 >E1HS99.1 E1HS99_ECOLX Putative glyoxylate reductase Length = 310 Score = 333 bits (855), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 170/311 (54%), Positives = 220/311 (70%), Gaps = 3/311 (0%) Query: 6 RPHVLIVARLPQHLLDLLQQHYTCHNLILQPHSEAELAAIAPQIRGIAANGEAKVSREFM 65 + VL A LP L L Q Y ++L L S+ EL A+A +I + NGEA V+REF+ Sbjct: 2 KQKVLKQAYLPDALTWELSQRYDLYDLAL--LSDTELQAVASEIAVVITNGEAVVTREFI 59 Query: 66 ARFPALEIVSVFGVGYDGVDVPAARERGIHVTHTPDVLNDDVADLAIALMLATARNVVRA 125 PAL++++VFGVGYDGVDV AAR+ G+ VTHTP VL DDVADLA+ LMLA +R +V A Sbjct: 60 NTLPALKLIAVFGVGYDGVDVAAARDAGVDVTHTPGVLTDDVADLAMGLMLAVSRKIVAA 119 Query: 126 DRFARSGEWKKGPFPFTTKVSGARLGIVGLGRIGQAIAKRAAAFDMQISYHNRSRKD-VP 184 +F W+ F +T KVSG RLGI+G+GRIGQAIA+RAAAFDM+ISY +R + + + Sbjct: 120 QKFIEQAGWQNSGFQWTRKVSGKRLGILGMGRIGQAIARRAAAFDMEISYSDRQKNNALI 179 Query: 185 YTYVDSITALAREVDFLVMITPGGAGTRALVNAEVLEALGPKGFLINVARGSVVDEAALI 244 + Y+ + ALA+ DFL++ PGG GT+AL+N VLEALG +G LIN++RGSVVDE ALI Sbjct: 180 WNYIPDLQALAQNSDFLMVCAPGGEGTKALINQSVLEALGAEGILINISRGSVVDEDALI 239 Query: 245 AALKTGVIAGAGLDVFADEPNVPAELAALDNVVLTPHMASGTLVTRTAMADLAFNNLQAH 304 AAL+ IAGA LDVFA EP+VP L DNVV+TPHMAS T TR M+ L N++A Sbjct: 240 AALENNTIAGAALDVFAHEPHVPVSLQKRDNVVITPHMASATWETRREMSRLVLENVEAW 299 Query: 305 FSGAGVISPVP 315 F+G +++PVP Sbjct: 300 FAGLPLVTPVP 310 >C4UWY3.1 C4UWY3_YERRO D-isomer specific 2-hydroxyacid dehydrogenase Length = 316 Score = 330 bits (845), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 172/314 (54%), Positives = 218/314 (69%), Gaps = 9/314 (2%) Query: 6 RPHVLIVARLPQHL---LDLLQQHYTCHNLILQPHSEAELAAIAPQIRGIAANGEAKVSR 62 + VL A LP L L+ L Y H++ + E +A + R + NGEA VSR Sbjct: 7 KQKVLKQASLPDQLNAQLNELYDVYEYHDMAAE-----EFDRLAAEFRVVLTNGEAVVSR 61 Query: 63 EFMARFPALEIVSVFGVGYDGVDVPAARERGIHVTHTPDVLNDDVADLAIALMLATARNV 122 EFMAR P LE++S FGVGYDG+DV AA+ER I VTHTP VL DDVADLA+ LMLAT+R + Sbjct: 62 EFMARLPNLELISDFGVGYDGIDVAAAKEREIAVTHTPGVLTDDVADLAMGLMLATSRQI 121 Query: 123 VRADRFARSGEWKKGPFPFTTKVSGARLGIVGLGRIGQAIAKRAAAFDMQISYHNRSR-K 181 A RF G W KG +P+T KVSGARLGI+G+GRIG+ IAKRAAAFDM I+Y +R+ Sbjct: 122 PGAQRFIEQGAWLKGSYPWTRKVSGARLGIIGMGRIGRTIAKRAAAFDMSIAYTDRAALA 181 Query: 182 DVPYTYVDSITALAREVDFLVMITPGGAGTRALVNAEVLEALGPKGFLINVARGSVVDEA 241 D+ YT+ ++ +LA DFLV+ T GGA TR+LVN EVL ALG +G LIN++RGSVVDE Sbjct: 182 DMDYTFHATLLSLAEASDFLVVCTNGGAETRSLVNREVLNALGAEGILINISRGSVVDER 241 Query: 242 ALIAALKTGVIAGAGLDVFADEPNVPAELAALDNVVLTPHMASGTLVTRTAMADLAFNNL 301 ALI A++ G + GAGLDVF DEP VP L +NVV+TPHMAS T TR M+ L N+ Sbjct: 242 ALIEAIEEGTLGGAGLDVFTDEPQVPQALLHRENVVITPHMASATWATRKEMSRLVLENV 301 Query: 302 QAHFSGAGVISPVP 315 A+F+G +++P+P Sbjct: 302 NAYFAGEPLVTPIP 315 >D8MLQ8.1 D8MLQ8_ERWBE D-isomer specific 2-hydroxyacid dehydrogenase (NAD-binding) Length = 313 Score = 328 bits (840), Expect = 9e-88, Method: Compositional matrix adjust. Identities = 170/312 (54%), Positives = 218/312 (69%), Gaps = 3/312 (0%) Query: 6 RPHVLIVARLPQHLLDLLQQHYTCHNLILQPHSEAELAAIAPQIRGIAANGEAKVSREFM 65 + VL +A LP L+ LQ+ Y + S+ + + +A + + NGE V+RE + Sbjct: 2 KKKVLQLAGLPAPLMSALQEAYEV--VEYSTLSDRDFSGMAGEFEVVLTNGEGVVTREQI 59 Query: 66 ARFPALEIVSVFGVGYDGVDVPAARERGIHVTHTPDVLNDDVADLAIALMLATARNVVRA 125 A PAL++++VFGVGYDGVDV AAR+ + V+HTPDVL +DVADLA+ LMLAT+R + A Sbjct: 60 AALPALKLIAVFGVGYDGVDVQAARDHQVKVSHTPDVLTEDVADLALGLMLATSRQIPAA 119 Query: 126 DRFARSGEWKKGPFPFTTKVSGARLGIVGLGRIGQAIAKRAAAFDMQISYHNRS-RKDVP 184 F G+W +G FP+T KVSGA LGIVGLGRIGQA+A+RA AFDM I+Y NRS +DV Sbjct: 120 QTFIEKGKWSQGSFPWTRKVSGAALGIVGLGRIGQAVAQRAQAFDMSIAYCNRSPLQDVA 179 Query: 185 YTYVDSITALAREVDFLVMITPGGAGTRALVNAEVLEALGPKGFLINVARGSVVDEAALI 244 Y Y + ALA+E DFL++ PG A R L+N +VL+ALG G LINV RGSVVDE ALI Sbjct: 180 YRYQPDVVALAKECDFLLVCAPGTASNRHLINRDVLDALGCDGILINVGRGSVVDEQALI 239 Query: 245 AALKTGVIAGAGLDVFADEPNVPAELAALDNVVLTPHMASGTLVTRTAMADLAFNNLQAH 304 AAL G + GAGLDVF+DEP VPA L NVVLTPHMAS T TR AM+ L +N+ A Sbjct: 240 AALDAGTLGGAGLDVFSDEPRVPAALQNRPNVVLTPHMASATWATRQAMSQLVLDNVAAF 299 Query: 305 FSGAGVISPVPD 316 F+G+ ++SPVP+ Sbjct: 300 FNGSPLVSPVPE 311 >E8XUR9.1 E8XUR9_RAHSY D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein Length = 316 Score = 318 bits (815), Expect = 7e-85, Method: Compositional matrix adjust. Identities = 167/311 (53%), Positives = 212/311 (68%), Gaps = 3/311 (0%) Query: 6 RPHVLIVARLPQHLLDLLQQHYTCHNLILQPHSEAELAAIAPQIRGIAANGEAKVSREFM 65 + +L A LP L L Y + + E +A + R + NGEA VSREFM Sbjct: 7 KQKILKQASLPDQLNAQLNALYDVYEY--NDMAAGEFDRLAAEFRVVLTNGEAVVSREFM 64 Query: 66 ARFPALEIVSVFGVGYDGVDVPAARERGIHVTHTPDVLNDDVADLAIALMLATARNVVRA 125 R P LE++S FGVGYDG+DV AARER I VTHTP VL DDVADLA+ L+LAT+R + A Sbjct: 65 GRLPNLELISDFGVGYDGIDVAAAREREIAVTHTPGVLTDDVADLAMGLILATSRQIPAA 124 Query: 126 DRFARSGEWKKGPFPFTTKVSGARLGIVGLGRIGQAIAKRAAAFDMQISYHNRSR-KDVP 184 RF G W+KG +P+T KVSGARLGI+G+GRIG+AIAKRAAAF+M I+Y +R+ D Sbjct: 125 QRFIEQGAWQKGGYPWTRKVSGARLGIIGMGRIGRAIAKRAAAFNMSIAYTDRAALADTD 184 Query: 185 YTYVDSITALAREVDFLVMITPGGAGTRALVNAEVLEALGPKGFLINVARGSVVDEAALI 244 YT+ ++ +LA DFLV+ T GGA TR LVN +VL ALG +G LIN++RGSVVDE AL Sbjct: 185 YTFHATLLSLAGASDFLVVCTNGGAETRGLVNRDVLNALGAEGILINISRGSVVDERALT 244 Query: 245 AALKTGVIAGAGLDVFADEPNVPAELAALDNVVLTPHMASGTLVTRTAMADLAFNNLQAH 304 A++ G + GAGLDVF DEP+VP L NVV+TPHMAS T TR M+ L N+ A+ Sbjct: 245 EAIEEGTLGGAGLDVFTDEPHVPHALLHRANVVVTPHMASATWATRKEMSRLVLENVNAY 304 Query: 305 FSGAGVISPVP 315 F+G +++PVP Sbjct: 305 FAGEPLVTPVP 315 >B1LXK8.1 B1LXK8_METRJ D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Length = 321 Score = 316 bits (809), Expect = 4e-84, Method: Compositional matrix adjust. Identities = 169/314 (53%), Positives = 213/314 (67%), Gaps = 13/314 (4%) Query: 12 VARLPQHLLDLLQQH----------YTCHNLILQPHSEAELAAIAPQIRGIAANGEAKVS 61 +A P +L L + H Y H L EA LA I P+IR + G V Sbjct: 1 MAEAPAEILLLRKMHPLVEKAFDGRYGVHRLAEAADPEALLAEIGPRIRALCVGG--AVD 58 Query: 62 REFMARFPALEIVSVFGVGYDGVDVPAARERGIHVTHTPDVLNDDVADLAIALMLATARN 121 M R P LE+++ FGVGYD VD AR+RGI VT+TPDVL D+VADLA+ L+LAT R Sbjct: 59 GALMDRLPNLELIANFGVGYDAVDAAGARQRGIVVTNTPDVLTDEVADLALGLVLATLRR 118 Query: 122 VVRADRFARSGEWKKGPFPFTTKVSGARLGIVGLGRIGQAIAKRAAAFDMQISYHNRSRK 181 + +ADR+ R G W K PFP T + G R+GI+GLGRIG+AIA+R +F ++I YH RSR+ Sbjct: 119 IPQADRYLRDGHWPKAPFPLTASLRGRRVGILGLGRIGRAIARRLESFGVEIDYHGRSRQ 178 Query: 182 -DVPYTYVDSITALAREVDFLVMITPGGAGTRALVNAEVLEALGPKGFLINVARGSVVDE 240 DVPYTY D++ LAR V L+++ PGGA TR LVNA VLEALGP+G LINVARG++VDE Sbjct: 179 ADVPYTYHDTLLGLARAVHILIVVAPGGADTRNLVNAAVLEALGPEGILINVARGTLVDE 238 Query: 241 AALIAALKTGVIAGAGLDVFADEPNVPAELAALDNVVLTPHMASGTLVTRTAMADLAFNN 300 AAL AAL+ G I GAGLDVF +EP+VPA+LAALDN VL PH+ S + TR AMA L +N Sbjct: 239 AALTAALRAGTILGAGLDVFENEPHVPADLAALDNTVLLPHVGSASEHTRAAMAQLVVDN 298 Query: 301 LQAHFSGAGVISPV 314 + + F G G ++PV Sbjct: 299 VVSWFEGRGPLTPV 312