BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0469.p (179 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IY83.1 D8IY83_HERSS HD-GYP domain containing protein 377 e-103 D8IXR6.1 D8IXR6_HERSS HD-GYP domain containing protein 233 9e-60 Q47JN5.1 Q47JN5_DECAR HDIG protein 218 3e-55 C7RPE3.1 C7RPE3_ACCPU Metal dependent phosphohydrolase 215 2e-54 D7DKX9.1 D7DKX9_METS0 Metal dependent phosphohydrolase 211 4e-53 C6X8F6.1 C6X8F6_METSD Metal dependent phosphohydrolase 210 6e-53 E4QPL3.1 E4QPL3_METS6 Metal dependent phosphohydrolase 210 6e-53 C9YFN1.1 C9YFN1_9BURK Putative uncharacterized protein 209 1e-52 Q3SIS7.1 Q3SIS7_THIDA Metal dependent phosphohydrolase, HD region 209 1e-52 B1XXA3.1 B1XXA3_LEPCP Metal dependent phosphohydrolase 207 4e-52 >D8IY83.1 D8IY83_HERSS HD-GYP domain containing protein Length = 401 Score = 377 bits (969), Expect = e-103, Method: Compositional matrix adjust. Identities = 179/179 (100%), Positives = 179/179 (100%) Query: 1 VRMHTVQGHGILQQIEGIGEVALDVSLHHHEKIDGSGYPFNLKADSISIMAKMGAVCDVY 60 VRMHTVQGHGILQQIEGIGEVALDVSLHHHEKIDGSGYPFNLKADSISIMAKMGAVCDVY Sbjct: 223 VRMHTVQGHGILQQIEGIGEVALDVSLHHHEKIDGSGYPFNLKADSISIMAKMGAVCDVY 282 Query: 61 DAITSNRPYKAGWDPARSIRHMAASAGHFDPITMQAFVKAIGIYPTGSCVMLQSGRLGVV 120 DAITSNRPYKAGWDPARSIRHMAASAGHFDPITMQAFVKAIGIYPTGSCVMLQSGRLGVV Sbjct: 283 DAITSNRPYKAGWDPARSIRHMAASAGHFDPITMQAFVKAIGIYPTGSCVMLQSGRLGVV 342 Query: 121 VDQRPDQLLTPRVKVFYSTANRMPLESEIIDLAHSSDKITAYADPAKWGIGNLPGIELL 179 VDQRPDQLLTPRVKVFYSTANRMPLESEIIDLAHSSDKITAYADPAKWGIGNLPGIELL Sbjct: 343 VDQRPDQLLTPRVKVFYSTANRMPLESEIIDLAHSSDKITAYADPAKWGIGNLPGIELL 401 >D8IXR6.1 D8IXR6_HERSS HD-GYP domain containing protein Length = 406 Score = 233 bits (594), Expect = 9e-60, Method: Compositional matrix adjust. Identities = 101/173 (58%), Positives = 134/173 (77%) Query: 1 VRMHTVQGHGILQQIEGIGEVALDVSLHHHEKIDGSGYPFNLKADSISIMAKMGAVCDVY 60 V+ H + GH +LQ++ GIG+ LDVSLHHHEK+DG+GYP+ L IS+ A+MGA+CDVY Sbjct: 226 VQSHPLAGHRLLQELPGIGDAPLDVSLHHHEKMDGTGYPYKLSGRDISMTARMGAICDVY 285 Query: 61 DAITSNRPYKAGWDPARSIRHMAASAGHFDPITMQAFVKAIGIYPTGSCVMLQSGRLGVV 120 DAITS+RPYK+GWDP+RSI+HMA S GHFD +QAFVKA+GIYP GSCV++Q+G L +V Sbjct: 286 DAITSDRPYKSGWDPSRSIQHMAQSKGHFDFDVLQAFVKAVGIYPVGSCVLMQTGHLAMV 345 Query: 121 VDQRPDQLLTPRVKVFYSTANRMPLESEIIDLAHSSDKITAYADPAKWGIGNL 173 ++QRPD LL P V++FYST ++ + +IDL S++KI DP KWG+ L Sbjct: 346 LEQRPDSLLAPLVRIFYSTNKKIAVTPTLIDLRRSANKIVGAVDPEKWGVTRL 398 >Q47JN5.1 Q47JN5_DECAR HDIG protein Length = 401 Score = 218 bits (554), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 102/173 (58%), Positives = 127/173 (73%) Query: 1 VRMHTVQGHGILQQIEGIGEVALDVSLHHHEKIDGSGYPFNLKADSISIMAKMGAVCDVY 60 V+ H G+ +L + GI E+ DV LHHHEKIDGSGYP L +D++S+ AKMGAVCDVY Sbjct: 220 VKTHPEAGYKLLLEGNGISEMTKDVCLHHHEKIDGSGYPKGLNSDTMSLFAKMGAVCDVY 279 Query: 61 DAITSNRPYKAGWDPARSIRHMAASAGHFDPITMQAFVKAIGIYPTGSCVMLQSGRLGVV 120 DA+TSNRPYKAGWDPA SI+ MA GHFDP QAFVK++GIYP GS V L+SG+LGVV Sbjct: 280 DAVTSNRPYKAGWDPAESIKRMAEWKGHFDPSVFQAFVKSLGIYPIGSFVRLESGKLGVV 339 Query: 121 VDQRPDQLLTPRVKVFYSTANRMPLESEIIDLAHSSDKITAYADPAKWGIGNL 173 ++Q LL P+VKVF+ST ++ + E IDLA S +KI D AKWGI ++ Sbjct: 340 IEQGEQSLLKPKVKVFFSTKSQAYIRPETIDLARSPEKIAGREDAAKWGIKDV 392 >C7RPE3.1 C7RPE3_ACCPU Metal dependent phosphohydrolase Length = 410 Score = 215 bits (548), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 106/177 (59%), Positives = 122/177 (68%), Gaps = 1/177 (0%) Query: 1 VRMHTVQGHGILQQIEGIGEVALDVSLHHHEKIDGSGYPFNLKADSISIMAKMGAVCDVY 60 ++ H +GH +L G VALDV LHHHEK DGSGYP LK ISI AKMGAVCDVY Sbjct: 225 IKSHPEEGHRMLLAGSGADAVALDVVLHHHEKTDGSGYPKRLKDQEISIFAKMGAVCDVY 284 Query: 61 DAITSNRPYKAGWDPARSIRHMAA-SAGHFDPITMQAFVKAIGIYPTGSCVMLQSGRLGV 119 DAITSNRPYKAGWDPA S+R MA S GHFDP QAFVK++GIYP GS V+L GRLGV Sbjct: 285 DAITSNRPYKAGWDPAESLRKMAEWSTGHFDPAVFQAFVKSVGIYPIGSLVLLSCGRLGV 344 Query: 120 VVDQRPDQLLTPRVKVFYSTANRMPLESEIIDLAHSSDKITAYADPAKWGIGNLPGI 176 V++Q LL PRVK+F+ST + EI+DLA KI + DPAKW +L I Sbjct: 345 VIEQGEKSLLQPRVKIFFSTRGNARVRPEIVDLARGQFKIVSREDPAKWNFPDLNEI 401 >D7DKX9.1 D7DKX9_METS0 Metal dependent phosphohydrolase Length = 405 Score = 211 bits (537), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 99/178 (55%), Positives = 127/178 (71%), Gaps = 2/178 (1%) Query: 1 VRMHTVQGHGILQQIEGIGEVALDVSLHHHEKIDGSGYPFNLKADSISIMAKMGAVCDVY 60 V++H +G+ +L + EV LDV LHHHEK++G+GYP LKA+ ISI AKMGAVCDVY Sbjct: 226 VKLHPERGYELLLKANITDEVTLDVCLHHHEKVNGTGYPKKLKAEEISIFAKMGAVCDVY 285 Query: 61 DAITSNRPYKAGWDPARSIRHMAASAGHFDPITMQAFVKAIGIYPTGSCVMLQSGRLGVV 120 DAITSNRPYK GW+P S++ MA GHFD + +AFVK++GIYP GS V L+SGRL VV Sbjct: 286 DAITSNRPYKDGWEPGVSLQRMAQWNGHFDEVVFKAFVKSVGIYPIGSMVKLKSGRLAVV 345 Query: 121 VDQRPDQLLTPRVKVFYSTANRMPLESEIIDLA--HSSDKITAYADPAKWGIGNLPGI 176 +DQ P LLTP VKVF+ST ++ + E+IDL+ H D I + DP WGI ++ I Sbjct: 346 IDQSPKSLLTPIVKVFFSTKSKSRINIELIDLSKPHEQDSIVGHEDPVLWGISDVHEI 403 >C6X8F6.1 C6X8F6_METSD Metal dependent phosphohydrolase Length = 415 Score = 210 bits (535), Expect = 6e-53, Method: Compositional matrix adjust. Identities = 105/176 (59%), Positives = 125/176 (71%), Gaps = 3/176 (1%) Query: 1 VRMHTVQGHGILQQIEGIGEVALDVSLHHHEKIDGSGYPFNLKADSISIMAKMGAVCDVY 60 VR H GH IL G+ EVALDV LHHHEK+DG+GYP L D ISI AKMGAVCDVY Sbjct: 234 VRGHPKAGHEILLASNGVDEVALDVCLHHHEKVDGTGYPHKLPNDEISIFAKMGAVCDVY 293 Query: 61 DAITSNRPYKAGWDPARSIRHMAA-SAGHFDPITMQAFVKAIGIYPTGSCVMLQSGRLGV 119 DA+TSNRPYK GW+P S++ MA S HFD +AFVK++GIYP GS VMLQSGRLGV Sbjct: 294 DAVTSNRPYKEGWEPGVSLQRMAQWSKTHFDDRVFKAFVKSVGIYPIGSMVMLQSGRLGV 353 Query: 120 VVDQRPDQLLTPRVKVFYSTANRMPLESEIIDLAHSS--DKITAYADPAKWGIGNL 173 VVDQ P LL P VKVF+ST +R + E++DL+ + DKI + DP WGI ++ Sbjct: 354 VVDQNPVSLLKPLVKVFFSTKSRTRIPVEVLDLSKPAVQDKIMGHEDPILWGIEDI 409 >E4QPL3.1 E4QPL3_METS6 Metal dependent phosphohydrolase Length = 415 Score = 210 bits (535), Expect = 6e-53, Method: Compositional matrix adjust. Identities = 105/176 (59%), Positives = 125/176 (71%), Gaps = 3/176 (1%) Query: 1 VRMHTVQGHGILQQIEGIGEVALDVSLHHHEKIDGSGYPFNLKADSISIMAKMGAVCDVY 60 VR H GH IL G+ EVALDV LHHHEK+DG+GYP L D ISI AKMGAVCDVY Sbjct: 234 VRGHPKAGHEILLASNGVDEVALDVCLHHHEKVDGTGYPHKLPNDEISIFAKMGAVCDVY 293 Query: 61 DAITSNRPYKAGWDPARSIRHMAA-SAGHFDPITMQAFVKAIGIYPTGSCVMLQSGRLGV 119 DA+TSNRPYK GW+P S++ MA S HFD +AFVK++GIYP GS VMLQSGRLGV Sbjct: 294 DAVTSNRPYKEGWEPGVSLQRMAQWSKTHFDDRVFKAFVKSVGIYPIGSMVMLQSGRLGV 353 Query: 120 VVDQRPDQLLTPRVKVFYSTANRMPLESEIIDLAHSS--DKITAYADPAKWGIGNL 173 VVDQ P LL P VKVF+ST +R + E++DL+ + DKI + DP WGI ++ Sbjct: 354 VVDQNPVSLLKPLVKVFFSTKSRTRIPVEVLDLSKPAVQDKIMGHEDPILWGIEDI 409 >C9YFN1.1 C9YFN1_9BURK Putative uncharacterized protein Length = 412 Score = 209 bits (533), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 103/176 (58%), Positives = 127/176 (72%), Gaps = 3/176 (1%) Query: 1 VRMHTVQGHGILQQIEGIGEVALDVSLHHHEKIDGSGYPFNLKADSISIMAKMGAVCDVY 60 ++ H +G+ +LQ + + LDV LHHHEK+DGSGYP LK + IS+ AKMGAVCDVY Sbjct: 225 IKKHPEEGYRLLQTGNAVDPMVLDVCLHHHEKVDGSGYPKGLKGEQISLFAKMGAVCDVY 284 Query: 61 DAITSNRPYKAGWDPARSIRHMAA-SAGHFDPITMQAFVKAIGIYPTGSCVMLQSGRLGV 119 DAITSNRPYK+GWDPA S+R MA ++GHFD QAFVK++GIYP GS V L SGRLGV Sbjct: 285 DAITSNRPYKSGWDPAESLRKMAEWASGHFDGKVFQAFVKSLGIYPIGSLVQLSSGRLGV 344 Query: 120 VVDQRPDQLLTPRVKVFYSTANRMPLESEIIDLAH--SSDKITAYADPAKWGIGNL 173 VV+Q L TP VKVFYST + M + EI+DL+ +SDKI + DPAKW +L Sbjct: 345 VVEQTAKSLTTPCVKVFYSTKSHMRIVPEIVDLSRPGNSDKIVSREDPAKWKFPDL 400 >Q3SIS7.1 Q3SIS7_THIDA Metal dependent phosphohydrolase, HD region Length = 404 Score = 209 bits (531), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 100/179 (55%), Positives = 129/179 (72%), Gaps = 3/179 (1%) Query: 1 VRMHTVQGHGILQQIEGIGEVALDVSLHHHEKIDGSGYPFNLKADSISIMAKMGAVCDVY 60 ++ H V+GH +L + + ++ LDV LHHHEK+DGSGYP L AD+IS+ AKMGAVCDVY Sbjct: 223 IQRHPVEGHRMLGECQQASDIVLDVCLHHHEKVDGSGYPDGLGADAISLFAKMGAVCDVY 282 Query: 61 DAITSNRPYKAGWDPARSIRHMAA-SAGHFDPITMQAFVKAIGIYPTGSCVMLQSGRLGV 119 DAITSNRPYKAGW PA S+R M S GHFD QAF+K +GIYP GS V L SGRLGV Sbjct: 283 DAITSNRPYKAGWCPAESVRKMTEWSRGHFDARVFQAFIKCVGIYPIGSLVKLDSGRLGV 342 Query: 120 VVDQRPDQLLTPRVKVFYSTANRMPLESEIIDLAH--SSDKITAYADPAKWGIGNLPGI 176 V++Q LL PRVK F+ST ++ + E++DL+ +++KI + DPAKWGI +L + Sbjct: 343 VIEQTDKSLLVPRVKAFFSTRSQTYIVPEVVDLSRPGANEKILGHEDPAKWGIKDLDAL 401 >B1XXA3.1 B1XXA3_LEPCP Metal dependent phosphohydrolase Length = 410 Score = 207 bits (528), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 98/175 (56%), Positives = 122/175 (69%), Gaps = 2/175 (1%) Query: 1 VRMHTVQGHGILQQIEGIGEVALDVSLHHHEKIDGSGYPFNLKADSISIMAKMGAVCDVY 60 +R H GH +L +ALDV LHHHEK+DGSGYP LKAD IS+ A+MGAVCDVY Sbjct: 224 MRQHPAWGHDLLLTSGDAPAMALDVCLHHHEKVDGSGYPHALKADQISLHAQMGAVCDVY 283 Query: 61 DAITSNRPYKAGWDPARSIRHMAASAGHFDPITMQAFVKAIGIYPTGSCVMLQSGRLGVV 120 DA+TS RPYKA WDP ++R MA GHF+P QAFVK +GIYP G+ V LQSGRLGVV Sbjct: 284 DAVTSARPYKAPWDPGEAVRQMAQWKGHFNPKVFQAFVKTVGIYPIGTLVKLQSGRLGVV 343 Query: 121 VDQRPDQLLTPRVKVFYSTANRMPLESEIIDLAH--SSDKITAYADPAKWGIGNL 173 +Q + LLTPRVKVF+ST + +P+ E++DLA ++D+I + P KW L Sbjct: 344 TEQNAESLLTPRVKVFFSTRSMLPVRQEVLDLAERTAADRIVSVEQPEKWNFKGL 398