BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0432.p (573 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IY55.1 D8IY55_HERSS Diguanylate cyclase/phosphodiesterase with... 1163 0.0 B2JUP6.1 B2JUP6_BURP8 Diguanylate cyclase/phosphodiesterase with... 272 1e-70 B5ZPN4.1 B5ZPN4_RHILW Diguanylate cyclase 239 1e-60 C6BM10.1 C6BM10_RALP1 Diguanylate cyclase/phosphodiesterase with... 234 3e-59 B2UKB8.1 B2UKB8_RALPJ Diguanylate cyclase/phosphodiesterase with... 234 3e-59 E1MHA6.1 E1MHA6_9GAMM Periplasmic/7TM domain sensor diguanylate ... 220 6e-55 D7DKL7.1 D7DKL7_METS0 Diguanylate cyclase 213 9e-53 Q3M5I8.1 Q3M5I8_ANAVT Putative diguanylate cyclase (GGDEF domain) 208 2e-51 A2SEH1.1 A2SEH1_METPP PleD 206 9e-51 A8FZK2.1 A8FZK2_SHESH Conserved hypothetical signaling protein 204 3e-50 >D8IY55.1 D8IY55_HERSS Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor domain protein Length = 573 Score = 1163 bits (3009), Expect = 0.0, Method: Compositional matrix adjust. Identities = 573/573 (100%), Positives = 573/573 (100%) Query: 1 MRKRLDFLSRHFLRRIAIGYRLISAFILVSLLPLLISGLLAYGETSRATQDKVRAYSVQV 60 MRKRLDFLSRHFLRRIAIGYRLISAFILVSLLPLLISGLLAYGETSRATQDKVRAYSVQV Sbjct: 1 MRKRLDFLSRHFLRRIAIGYRLISAFILVSLLPLLISGLLAYGETSRATQDKVRAYSVQV 60 Query: 61 VQQISQNLLLRMEKIEDTSEALALSEKMQRLLADYYSGDADASAAARNSAARVLLDTYGA 120 VQQISQNLLLRMEKIEDTSEALALSEKMQRLLADYYSGDADASAAARNSAARVLLDTYGA Sbjct: 61 VQQISQNLLLRMEKIEDTSEALALSEKMQRLLADYYSGDADASAAARNSAARVLLDTYGA 120 Query: 121 LTYVNQKYLLDRDRQVIDPQIFAPLASSIGRVAEEAPELTGRGWWTLYHAGHGQKSLAML 180 LTYVNQKYLLDRDRQVIDPQIFAPLASSIGRVAEEAPELTGRGWWTLYHAGHGQKSLAML Sbjct: 121 LTYVNQKYLLDRDRQVIDPQIFAPLASSIGRVAEEAPELTGRGWWTLYHAGHGQKSLAML 180 Query: 181 REVRFTANNRPAGVLFVGVHPSYFFDIFRGADLGYGASISIVDASDGAVVVQSRESSASQ 240 REVRFTANNRPAGVLFVGVHPSYFFDIFRGADLGYGASISIVDASDGAVVVQSRESSASQ Sbjct: 181 REVRFTANNRPAGVLFVGVHPSYFFDIFRGADLGYGASISIVDASDGAVVVQSRESSASQ 240 Query: 241 ADPALLGGITESLAQGRDSDFIAYVGADKTPYYAAIARLPHTSWWVASITPSDRLNADTR 300 ADPALLGGITESLAQGRDSDFIAYVGADKTPYYAAIARLPHTSWWVASITPSDRLNADTR Sbjct: 241 ADPALLGGITESLAQGRDSDFIAYVGADKTPYYAAIARLPHTSWWVASITPSDRLNADTR 300 Query: 301 SVRDKIIAIGLVCFAVSLLLSALISRSISVPLQRLVAAMKEAGSGDTTVRVEQHGNDEIA 360 SVRDKIIAIGLVCFAVSLLLSALISRSISVPLQRLVAAMKEAGSGDTTVRVEQHGNDEIA Sbjct: 301 SVRDKIIAIGLVCFAVSLLLSALISRSISVPLQRLVAAMKEAGSGDTTVRVEQHGNDEIA 360 Query: 361 VLSRKFNEMAGKLQQNREVLEEQVRLRTRELERANRKLEALSATDGLTGVANRRRFDEAL 420 VLSRKFNEMAGKLQQNREVLEEQVRLRTRELERANRKLEALSATDGLTGVANRRRFDEAL Sbjct: 361 VLSRKFNEMAGKLQQNREVLEEQVRLRTRELERANRKLEALSATDGLTGVANRRRFDEAL 420 Query: 421 ANEMRRAVRSGQSLALLMLDVDYFKKYNDRYGHLAGDECLRIVARVLQKSSRRATDLVAR 480 ANEMRRAVRSGQSLALLMLDVDYFKKYNDRYGHLAGDECLRIVARVLQKSSRRATDLVAR Sbjct: 421 ANEMRRAVRSGQSLALLMLDVDYFKKYNDRYGHLAGDECLRIVARVLQKSSRRATDLVAR 480 Query: 481 YGGEEFSVIIAECDTTQALQQAENICQAIFELKLPHADSPFGYISASIGVAVLLPDEHTA 540 YGGEEFSVIIAECDTTQALQQAENICQAIFELKLPHADSPFGYISASIGVAVLLPDEHTA Sbjct: 481 YGGEEFSVIIAECDTTQALQQAENICQAIFELKLPHADSPFGYISASIGVAVLLPDEHTA 540 Query: 541 PEQMVRIADQALYHAKYQGRNRVVLGSDATQGL 573 PEQMVRIADQALYHAKYQGRNRVVLGSDATQGL Sbjct: 541 PEQMVRIADQALYHAKYQGRNRVVLGSDATQGL 573 >B2JUP6.1 B2JUP6_BURP8 Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) Length = 980 Score = 272 bits (695), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 154/420 (36%), Positives = 250/420 (59%), Gaps = 24/420 (5%) Query: 1 MRKRLDFLSRHFLRRIAIGYRLISAFILVSLLPLLISGLLAYGETSRATQDKVRAYSVQV 60 +++ ++LS+ LRR+ I YRL++AFIL+SLLP+LISG ++Y E++ A ++K +S +V Sbjct: 8 LQRAFEYLSQDLLRRVEIRYRLMTAFILLSLLPVLISGYISYAESTAAIKEKAEIFSKEV 67 Query: 61 VQQISQNLLLRMEKIEDTSEALALSEKMQRLLADYYSGDADASAAARNSAARVLLDTYGA 120 V+Q+S+N++LRME++E S L LS+++Q L SG AR R+LLD YG+ Sbjct: 68 VKQVSRNVVLRMEQVETESSLLVLSDQVQAALMKVESGSPKEQNEARQDMTRLLLDHYGS 127 Query: 121 LTYVNQKYLLDRDRQVIDPQIFAPLASSIGRVAEEAPELTGRGWWTLYHAGHGQKSLAML 180 + ++N+KYLLD+ +V+D Q FA L + R +A + GR +W Y G GQ++L M+ Sbjct: 128 VDFINEKYLLDQHDRVMDTQAFAQLTRGVMRFVRQALQHNGRPYWGSYDNGVGQQNLGMV 187 Query: 181 REVRFTANNRPAGVLFVGVHPSYFFDIFRGADLGYGASISIVDASDGAVVVQSRESSA-- 238 R V +NNR G L + + P +F IF LG G I ++D S+ ++V++ ++ A Sbjct: 188 RAVIGKSNNRQLGHLVLVIRPEHFSTIFNDVALGTGTQIYVLDTSNNKLIVRADDTPAGA 247 Query: 239 -SQADPALLGGIT---ESLAQGRDSDFIAYVGADKTPYYAAIARLPHTSWWVASITPSDR 294 + A+P L+ IT E+L G + F+++ G ++ Y+AA R+P T+W+V S P + Sbjct: 248 DAAAEPGLIDKITHNNETL--GEPNGFVSFEGKNRAGYFAAYTRIPGTTWFVVSTIPEKK 305 Query: 295 LNADTRSVRDKIIAIGLVCFAVSLLLSALISRSISVPLQRLVAAMKEAGSGD-------T 347 L A+ +SVR++++ +G+ F +S+ + IS SIS PL+ LV M + GS Sbjct: 306 LTAEAQSVRNQMVLVGISGFLLSIFFAYFISHSISAPLKNLVRKMHDTGSDAGAESEDLA 365 Query: 348 TVRVEQHGNDEIAVLSRKFNEMAG----KLQQNREV---LEEQVRLRTRELERANRKLEA 400 V G DE+ L ++F M K+Q+ E+ LE+ V RT EL +R+LE+ Sbjct: 366 QAPVGSDGQDELGRLEQRFERMRAAIRQKIQKINEINASLEQTVAERTAEL--VSRELES 423 Score = 107 bits (266), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 69/161 (42%), Positives = 94/161 (58%), Gaps = 7/161 (4%) Query: 405 DGLTGVANRRRFDEALANEMRRAVRSGQSLALLMLDVDYFKKYNDRYGHLAGDECLRIVA 464 D LT + NR+ F L E + A RSG +AL+++D+D FK+ ND GH GD L A Sbjct: 549 DTLTQLPNRQMFQNRLEQEAKVAQRSGHRMALMLIDLDRFKEVNDSLGHDTGDTLLIEAA 608 Query: 465 RVLQKSSRRATDLVARYGGEEFSVIIAECDTTQALQQAENICQAIFE-LKLPHADSP-FG 522 R + S R +D VAR GG+EF+VI+ + D ++ E I + I E L P A P Sbjct: 609 RRI-TSCVRESDTVARLGGDEFTVILPDIDNCGSI---ERIARTIIETLSEPFALGPDEA 664 Query: 523 YISASIGVAVLLPDEHTAPEQMVRIADQALYHAKYQGRNRV 563 +ISASIGV V PD+ + + + ADQA+Y AK GRNR+ Sbjct: 665 FISASIGVTV-YPDDARELDVLFKNADQAMYAAKNAGRNRL 704 >B5ZPN4.1 B5ZPN4_RHILW Diguanylate cyclase Length = 660 Score = 239 bits (609), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 129/305 (42%), Positives = 191/305 (62%), Gaps = 10/305 (3%) Query: 268 DKTPYYAAIARLPHTSWWVASITPSDRLNADTRSVRDKIIAIGLVCFAVSL-LLSALISR 326 + T A+ R+P T W +A P + + ++A+GL+ V L +L +++ + Sbjct: 345 ESTSEITAVGRIPDTPWVLAVHYPKSLMRPAILTNLGIVVAVGLLTLFVELFILRSILQK 404 Query: 327 SISVPLQRLVAAMKEAGSGDTTVR---VEQHGNDEIAVLSRKFNEMAGKLQQNREVLEEQ 383 ++ PL RL+ A + G TV + H +DEI L+R F MA ++ E LE + Sbjct: 405 QVAEPLVRLIHATQLVGRSGVTVANDALPTHSDDEIGELARDFASMAARVHTAHEALEGK 464 Query: 384 VRLRTRELERANRKLEALSATDGLTGVANRRRFDEALANEMRRAVRSGQSLALL-MLDVD 442 +R RT ELER N+KL +S TD +TGVANRRRFDE LA+E+ + GQ L +L M+D D Sbjct: 465 IRDRTSELERLNQKLLTISQTDEMTGVANRRRFDEVLASELA-GLGQGQDLLMLAMVDAD 523 Query: 443 YFKKYNDRYGHLAGDECLRIVARVLQKSSRRATDLVARYGGEEFSVI--IAECDTTQALQ 500 +FK YNDRYGH AGD CL+ +ARVL++++R D+VARYGGEEF++I IA + Sbjct: 524 WFKGYNDRYGHPAGDACLKEIARVLERNTRSKQDVVARYGGEEFAIIARIASASNAPVIG 583 Query: 501 QAENICQAIFELKLPHADSPFGYISASIGVAVLLPDEHTAPEQMVRIADQALYHAKYQGR 560 QA +C A+ +KL H SPFG+++ S+G+A+ PD++ +PE ++ AD+ALY AK GR Sbjct: 584 QA--LCSAMATVKLAHEGSPFGHVTLSVGIALAAPDQNISPEALLLEADRALYRAKQAGR 641 Query: 561 NRVVL 565 N+ V+ Sbjct: 642 NQAVV 646 >C6BM10.1 C6BM10_RALP1 Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) Length = 980 Score = 234 bits (597), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 141/418 (33%), Positives = 233/418 (55%), Gaps = 21/418 (5%) Query: 1 MRKRLDFLSRHFLRRIAIGYRLISAFILVSLLPLLISGLLAYGETSRATQDKVRAYSVQV 60 +++ D+LS+ LRR+ I +RL++AFIL+SLLP+ IS ++Y + A ++ +S +V Sbjct: 8 LQRAFDYLSQDLLRRVEIRHRLVAAFILLSLLPICISASISYVNSIAAIKENAEIFSKEV 67 Query: 61 VQQISQNLLLRMEKIEDTSEALALSEKMQRLLADYYSGDADASAAARNSAARVLLDTYGA 120 V+Q+S+N+ LRM +IE S L LS ++Q LA SG+ + AR AR+LL+ YG+ Sbjct: 68 VKQVSRNIELRMRQIEAESNLLVLSNQVQGALARAASGNGKEQSEARQDMARLLLEHYGS 127 Query: 121 LTYVNQKYLLDRDRQVIDPQIFAPLASSIGRVAEEAPELTGRGWWTLYHAGHGQKSLAML 180 + ++NQKYLLD++ +++D Q A L + R+ A ++ G +W Y G GQ+++ ++ Sbjct: 128 VDFINQKYLLDKNNRILDTQAAAQLTQGVTRLVSRAQDVHGHTYWGSYDNGVGQQNVGVV 187 Query: 181 REVRFTANNRPAGVLFVGVHPSYFFDIFRGADLGYGASISIVDASDGAVV--VQSRESSA 238 R + +NR G L + V P+YF IF G G I I+DAS+ ++ + + Sbjct: 188 RAIIDKNSNRQLGNLVLIVRPAYFSTIFNDVATGSGTQIFILDASNEVIIRAADAANDTG 247 Query: 239 SQADPALLGGITESLAQGRDSDFIAYVGADKTPYYAAIARLPHTSWWVASITPSDRLNAD 298 + +P LL I + G F+A G Y AA A++P T+W+V S +L A+ Sbjct: 248 ALPEPGLLENIARNATAGEARSFVAIEGKRGGRYLAAYAKIPGTTWFVVSTIAEKKLTAE 307 Query: 299 TRSVRDKIIAIGLVCFAVSLLLSALISRSISVPLQRLVAAMKEAGSGDTTVRVEQ----- 353 ++VR++I +G+ +S+ L+ IS SIS PL+ LV + + G D +V++ Sbjct: 308 AQAVRNQIALVGISGVLLSIFLAYFISHSISAPLRELVRKVHDTGD-DAGAQVDEGKHVE 366 Query: 354 ---HGNDEIAVLSRKFNEMAGKLQQNRE-------VLEEQVRLRTREL---ERANRKL 398 DE++ L+++F M ++Q E LE+ V RT EL ER +R L Sbjct: 367 AGARAKDELSRLAQRFERMREAIKQKIEKINEINASLEQTVIERTAELVTRERESRTL 424 Score = 97.1 bits (240), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 63/159 (39%), Positives = 91/159 (57%), Gaps = 5/159 (3%) Query: 405 DGLTGVANRRRFDEALANEMRRAVRSGQSLALLMLDVDYFKKYNDRYGHLAGDECLRIVA 464 D LTG+ NR+ F E LA E + R G+ +AL+++D+D FK+ ND GH GD L I A Sbjct: 547 DALTGLPNRQMFHERLAQEASQPGRIGRRMALMLIDLDRFKEVNDSLGHDRGDTLL-IEA 605 Query: 465 RVLQKSSRRATDLVARYGGEEFSVIIAECDTTQALQQ-AENICQAIFELKLPHADSPFGY 523 + R +D VAR GG+EF+VI+ D +++++ A I + E D F Sbjct: 606 GKRIGACVRQSDTVARLGGDEFTVILPNLDDAESVERIASTIIDKLAEPFKLGTDEAF-- 663 Query: 524 ISASIGVAVLLPDEHTAPEQMVRIADQALYHAKYQGRNR 562 +SAS+GV PD+ + + + ADQA+Y AK GRNR Sbjct: 664 VSASVGV-TFYPDDAHDLDVLFKNADQAMYAAKNAGRNR 701 >B2UKB8.1 B2UKB8_RALPJ Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) Length = 980 Score = 234 bits (597), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 141/418 (33%), Positives = 233/418 (55%), Gaps = 21/418 (5%) Query: 1 MRKRLDFLSRHFLRRIAIGYRLISAFILVSLLPLLISGLLAYGETSRATQDKVRAYSVQV 60 +++ D+LS+ LRR+ I +RL++AFIL+SLLP+ IS ++Y + A ++ +S +V Sbjct: 8 LQRAFDYLSQDLLRRVEIRHRLVAAFILLSLLPICISASISYVNSIAAIKENAEIFSKEV 67 Query: 61 VQQISQNLLLRMEKIEDTSEALALSEKMQRLLADYYSGDADASAAARNSAARVLLDTYGA 120 V+Q+S+N+ LRM +IE S L LS ++Q LA SG+ + AR AR+LL+ YG+ Sbjct: 68 VKQVSRNIELRMRQIEAESNLLVLSNQVQGALARAASGNGKEQSEARQDMARLLLEHYGS 127 Query: 121 LTYVNQKYLLDRDRQVIDPQIFAPLASSIGRVAEEAPELTGRGWWTLYHAGHGQKSLAML 180 + ++NQKYLLD++ +++D Q A L + R+ A ++ G +W Y G GQ+++ ++ Sbjct: 128 VDFINQKYLLDKNNRILDTQAAAQLTQGVTRLVSRAQDVHGHTYWGSYDNGVGQQNVGVV 187 Query: 181 REVRFTANNRPAGVLFVGVHPSYFFDIFRGADLGYGASISIVDASDGAVV--VQSRESSA 238 R + +NR G L + V P+YF IF G G I I+DAS+ ++ + + Sbjct: 188 RAIIDKNSNRQLGNLVLIVRPAYFSTIFNDVATGSGTQIFILDASNEVIIRAADAANDTG 247 Query: 239 SQADPALLGGITESLAQGRDSDFIAYVGADKTPYYAAIARLPHTSWWVASITPSDRLNAD 298 + +P LL I + G F+A G Y AA A++P T+W+V S +L A+ Sbjct: 248 ALPEPGLLENIARNATAGEARSFVAIEGKRGGRYLAAYAKIPGTTWFVVSTIAEKKLTAE 307 Query: 299 TRSVRDKIIAIGLVCFAVSLLLSALISRSISVPLQRLVAAMKEAGSGDTTVRVEQ----- 353 ++VR++I +G+ +S+ L+ IS SIS PL+ LV + + G D +V++ Sbjct: 308 AQAVRNQIALVGISGVLLSIFLAYFISHSISAPLRELVRKVHDTGD-DAGAQVDEGKHVE 366 Query: 354 ---HGNDEIAVLSRKFNEMAGKLQQNRE-------VLEEQVRLRTREL---ERANRKL 398 DE++ L+++F M ++Q E LE+ V RT EL ER +R L Sbjct: 367 AGARAKDELSRLAQRFERMREAIKQKIEKINEINASLEQTVIERTAELVTRERESRTL 424 Score = 97.1 bits (240), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 63/159 (39%), Positives = 91/159 (57%), Gaps = 5/159 (3%) Query: 405 DGLTGVANRRRFDEALANEMRRAVRSGQSLALLMLDVDYFKKYNDRYGHLAGDECLRIVA 464 D LTG+ NR+ F E LA E + R G+ +AL+++D+D FK+ ND GH GD L I A Sbjct: 547 DALTGLPNRQMFHERLAQEASQPGRIGRRMALMLIDLDRFKEVNDSLGHDRGDTLL-IEA 605 Query: 465 RVLQKSSRRATDLVARYGGEEFSVIIAECDTTQALQQ-AENICQAIFELKLPHADSPFGY 523 + R +D VAR GG+EF+VI+ D +++++ A I + E D F Sbjct: 606 GKRIGACVRQSDTVARLGGDEFTVILPNLDDAESVERIASTIIDKLAEPFKLGTDEAF-- 663 Query: 524 ISASIGVAVLLPDEHTAPEQMVRIADQALYHAKYQGRNR 562 +SAS+GV PD+ + + + ADQA+Y AK GRNR Sbjct: 664 VSASVGV-TFYPDDAHDLDVLFKNADQAMYAAKNAGRNR 701 >E1MHA6.1 E1MHA6_9GAMM Periplasmic/7TM domain sensor diguanylate cyclase Length = 680 Score = 220 bits (560), Expect = 6e-55, Method: Compositional matrix adjust. Identities = 111/201 (55%), Positives = 140/201 (69%), Gaps = 1/201 (0%) Query: 372 KLQQNREVLEEQVRLRTRELERANRKLEALSATDGLTGVANRRRFDEALANEMRRAVRSG 431 L+ + +LE +V RT EL+ NRKLEALS TD LTG+ANRRRFD L +E RA R G Sbjct: 465 NLKSSEHLLEIRVAERTDELQLLNRKLEALSTTDELTGIANRRRFDAKLLSEWSRAARLG 524 Query: 432 QSLALLMLDVDYFKKYNDRYGHLAGDECLRIVARVLQKSSRRATDLVARYGGEEFSVIIA 491 Q LAL +LDVD+FKKYND YGH GDECLRI+A VL + R DLVARYGGEEF I Sbjct: 525 QPLALAVLDVDWFKKYNDHYGHQKGDECLRIIAEVLSANICRTGDLVARYGGEEFVFIAP 584 Query: 492 ECDTTQALQQAENICQAIFELKLPHADSPFGYISASIGVAVLLPDEHTAPEQMVRIADQA 551 D AL A IC+A+ L LPH S FG+++ASIGVA ++P++ +P+ +++ AD+A Sbjct: 585 TTDGAIALNMAWKICEALQSLALPHEMSGFGWVTASIGVAAIVPEQKLSPDMLIKAADEA 644 Query: 552 LYHAKYQGRNRVVLG-SDATQ 571 LY AK QGRN+ VL +D T+ Sbjct: 645 LYRAKKQGRNQAVLAVTDETE 665 >D7DKL7.1 D7DKL7_METS0 Diguanylate cyclase Length = 485 Score = 213 bits (541), Expect = 9e-53, Method: Compositional matrix adjust. Identities = 108/215 (50%), Positives = 139/215 (64%), Gaps = 3/215 (1%) Query: 354 HGNDEIAVLS---RKFNEMAGKLQQNREVLEEQVRLRTRELERANRKLEALSATDGLTGV 410 H + IA+LS F + +++ N LE++V RT EL+ N KLE LS TDGLTG+ Sbjct: 270 HAQEFIAILSIASMGFATLLSRIRDNERELEDRVSKRTDELQLLNHKLEGLSKTDGLTGI 329 Query: 411 ANRRRFDEALANEMRRAVRSGQSLALLMLDVDYFKKYNDRYGHLAGDECLRIVARVLQKS 470 ANRR FD+ L E RA R+ Q LAL MLD+D+FK+YND YGH AGDECLR V+ +L + Sbjct: 330 ANRRSFDDVLEIEWMRAKRANQPLALAMLDIDWFKRYNDHYGHQAGDECLRRVSNILASN 389 Query: 471 SRRATDLVARYGGEEFSVIIAECDTTQALQQAENICQAIFELKLPHADSPFGYISASIGV 530 R DLVARYGGEEF I QAL+ + IC+A+ L LPH S FGY++ S+GV Sbjct: 390 LCRTGDLVARYGGEEFVFIAPAISGDQALEISRKICEALHSLALPHELSTFGYVTVSVGV 449 Query: 531 AVLLPDEHTAPEQMVRIADQALYHAKYQGRNRVVL 565 A + P + +V++AD ALY AK QGRNR +L Sbjct: 450 ASITPQGSQKSDVLVKMADDALYQAKEQGRNRALL 484 >Q3M5I8.1 Q3M5I8_ANAVT Putative diguanylate cyclase (GGDEF domain) Length = 591 Score = 208 bits (530), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 116/290 (40%), Positives = 173/290 (59%), Gaps = 3/290 (1%) Query: 275 AIARLPHTSWWVASITP-SDRLNADTRSVRDKIIAIGLVCFAVSLLLSALISRSISVPLQ 333 AIA L + W V P L + + D + L+ V+++ A I + ++ P+ Sbjct: 297 AIASLKYKPWSVLFAQPLVVALAPVEKQIHDAMFLFVLIASVVTIIAFA-IGQLLTRPII 355 Query: 334 RLVAAMKEAGSGDTTVRVEQHGNDEIAVLSRKFNEMAGKLQQNREVLEEQVRLRTRELER 393 L + + +G+ +R + DEI L++ FN MA +LQ + E LE++V+ RT EL Sbjct: 356 YLTNIVFQFTTGNLNIRAKISSTDEIGQLAKSFNNMAFQLQTSFETLEQRVQERTAELVI 415 Query: 394 ANRKLEALSATDGLTGVANRRRFDEALANEMRRAVRSGQSLALLMLDVDYFKKYNDRYGH 453 AN+KLE L DGLT VANRR FDE L E +R R Q L+L++ DVD FK YND YGH Sbjct: 416 ANQKLEQLVNLDGLTQVANRRCFDERLKAEWKRLAREQQPLSLILFDVDKFKSYNDYYGH 475 Query: 454 LAGDECLRIVARVLQKSSRRATDLVARYGGEEFSVIIAECDTTQALQQAENICQAIFELK 513 L GD+CL +A+ +Q+ R DL+ARYGGEEFS+++ D A++ A+ I QAI++ Sbjct: 476 LGGDDCLITIAQAVQQKLHRPADLLARYGGEEFSILLPNTDLLGAIKVAQIIQQAIYDQA 535 Query: 514 LPHADSPF-GYISASIGVAVLLPDEHTAPEQMVRIADQALYHAKYQGRNR 562 +PHA S ++ S+G+ ++P P+ ++ AD+ALY+AK QGR+R Sbjct: 536 IPHAQSDIKDIVTLSLGITSIIPAGDINPDTLIASADKALYNAKQQGRDR 585 >A2SEH1.1 A2SEH1_METPP PleD Length = 511 Score = 206 bits (524), Expect = 9e-51, Method: Compositional matrix adjust. Identities = 111/190 (58%), Positives = 136/190 (71%) Query: 380 LEEQVRLRTRELERANRKLEALSATDGLTGVANRRRFDEALANEMRRAVRSGQSLALLML 439 LE++VR RT +LE +N +L LS TDGLTG+ANRRRFDE +A E R A +GQ LAL +L Sbjct: 320 LEDKVRERTLKLEESNSQLGTLSTTDGLTGIANRRRFDEFIAGEWRHARVTGQPLALALL 379 Query: 440 DVDYFKKYNDRYGHLAGDECLRIVARVLQKSSRRATDLVARYGGEEFSVIIAECDTTQAL 499 DVD FK YNDRYGH AGD+CLR +A+VL + RRA DLVARYGGEEF+++ D AL Sbjct: 380 DVDLFKHYNDRYGHQAGDDCLRTIAQVLGANVRRAGDLVARYGGEEFALVAVAADEASAL 439 Query: 500 QQAENICQAIFELKLPHADSPFGYISASIGVAVLLPDEHTAPEQMVRIADQALYHAKYQG 559 + ICQA+ L H SPFG ++ASIGVAVL+P EH E ++R AD+ALY AK G Sbjct: 440 AMSRGICQALEALAHRHELSPFGVVTASIGVAVLVPGEHDTHETLIRRADRALYQAKANG 499 Query: 560 RNRVVLGSDA 569 RN+ VL DA Sbjct: 500 RNQAVLAGDA 509 >A8FZK2.1 A8FZK2_SHESH Conserved hypothetical signaling protein Length = 480 Score = 204 bits (520), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 114/292 (39%), Positives = 170/292 (58%), Gaps = 12/292 (4%) Query: 274 AAIARLPHTSWWVASITPSDRLNADTRSVRDKIIAIGLVCFAVSLLLSALISRSISVPLQ 333 AAI + T W+VA+ + R + + ++ ++ + +L+ + ++ PL+ Sbjct: 198 AAITSIESTGWFVATRQKTTEAYLPVRQLTESMLMYLVLSAILGVLIITFVFITMLSPLK 257 Query: 334 RLVAAMKEAGSGDTTVR-VEQHGNDEIAVLSRKFNEMAGKLQQNREVLEEQVRLRTRELE 392 + ++K+ G+T ++ + DE+ L FN + + + RT LE Sbjct: 258 KAALSVKDMAQGNTPLKKLTIVHKDEVGDLIDGFNSLV-----------DAIDGRTDALE 306 Query: 393 RANRKLEALSATDGLTGVANRRRFDEALANEMRRAVRSGQSLALLMLDVDYFKKYNDRYG 452 AN+KL ALS TD LTG+ NRR F+E L E RA R+ Q LAL M+D+D+FKKYND+YG Sbjct: 307 TANQKLAALSLTDELTGLGNRRHFNEKLEQEWIRASRTKQPLALGMIDIDFFKKYNDKYG 366 Query: 453 HLAGDECLRIVARVLQKSSRRATDLVARYGGEEFSVIIAECDTTQALQQAENICQAIFEL 512 H+ GDECL+ ++++L RA DL ARYGGEEF+ I D A AE +A+ L Sbjct: 367 HVLGDECLQEISKLLASIISRAGDLSARYGGEEFAFIAPATDEEGARDIAEKFQEALHSL 426 Query: 513 KLPHADSPFGYISASIGVAVLLPDEHTAPEQMVRIADQALYHAKYQGRNRVV 564 LPH +S FG+++ASIG+AV P + +++IAD+ALY AK QGRNRVV Sbjct: 427 TLPHVESEFGFVTASIGIAVRTPTKGEESICLIKIADEALYLAKEQGRNRVV 478