BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0429.p (406 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IY53.1 D8IY53_HERSS Permease of the major facilitator superfam... 801 0.0 Q1LE12.1 Q1LE12_RALME Drug resistance transporter Bcr/CflA subfa... 402 e-110 B3RA15.1 B3RA15_CUPTR Bicyclomycin resistance protein ;Sulfonami... 398 e-109 Q0K1V2.1 Q0K1V2_CUPNH MFS transporter, DHA1 family 394 e-107 Q46TZ2.1 Q46TZ2_CUPPJ Drug resistance transporter Bcr/CflA subfa... 380 e-103 E4PI85.1 E4PI85_MARAH Drug resistance transporter, Bcr/CflA fami... 364 2e-98 D8N9U3.1 D8N9U3_RALSO Putative bicyclomycin/multidrug efflux sys... 362 5e-98 D8P115.1 D8P115_RALSO Putative bicyclomycin/multidrug efflux sys... 360 2e-97 A3RR62.1 A3RR62_RALSO Transmembrane drug transport protein, MFS ... 360 3e-97 Q8XXE2.1 Q8XXE2_RALSO Probable drug transport transmembrane protein 357 1e-96 >D8IY53.1 D8IY53_HERSS Permease of the major facilitator superfamily protein Length = 406 Score = 801 bits (2069), Expect = 0.0, Method: Compositional matrix adjust. Identities = 404/406 (99%), Positives = 405/406 (99%) Query: 1 MQNNDTSLSTGKFPAWLAVLAGLTAMGALAIDMYLPSFTAIAQDLGVGTNQVQLTLATFL 60 MQNNDTSLSTGKFPAWLAVLAGLTAMGALAIDMYLPSFTAIAQDLGVGTNQVQLTLATFL Sbjct: 1 MQNNDTSLSTGKFPAWLAVLAGLTAMGALAIDMYLPSFTAIAQDLGVGTNQVQLTLATFL 60 Query: 61 IGVAVGQMFYGPLSDRFGRKPPLFFGIALYFVCSLLCIFAQNIETLIVLRLFQGLGGSAG 120 IGVAVGQMFYGPLSDRFGRKPPLFFGIALYFVCSLLCIFAQNIETLIVLRLFQGLGGSAG Sbjct: 61 IGVAVGQMFYGPLSDRFGRKPPLFFGIALYFVCSLLCIFAQNIETLIVLRLFQGLGGSAG 120 Query: 121 MVIPRAMVRDRMGAEGSAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGL 180 MVIPRAMVRDRMGAEGSAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGL Sbjct: 121 MVIPRAMVRDRMGAEGSAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGL 180 Query: 181 LCILGTRKYLTETVDVSRAEPLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAG 240 LCILGTRKYLTETVDVSRAEPLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAG Sbjct: 181 LCILGTRKYLTETVDVSRAEPLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAG 240 Query: 241 GPFVVIELHGVKPQYFGFVFASNAIGLIAASQVNARLVVKRSAERVLGKVLWVPAGLSLT 300 GPFVVIELHGVKPQYFGFVFASNAIGLIAASQVNARLVVKRSAERVLGKVLWVPAGLSLT Sbjct: 241 GPFVVIELHGVKPQYFGFVFASNAIGLIAASQVNARLVVKRSAERVLGKVLWVPAGLSLT 300 Query: 301 VALLVLAGLETLPLLLLGFFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGSLQFGMG 360 V+LLVL GLETLPLLLLGFFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGSLQFGMG Sbjct: 301 VSLLVLVGLETLPLLLLGFFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGSLQFGMG 360 Query: 361 VLSGVAMSLWHDGTALPLVSVMAVCGVTALLVYHFAAKHAPAVSPQ 406 VLSGVAMSLWHDGTALPLVSVMAVCGVTALLVYHFAAKHAPAVSPQ Sbjct: 361 VLSGVAMSLWHDGTALPLVSVMAVCGVTALLVYHFAAKHAPAVSPQ 406 >Q1LE12.1 Q1LE12_RALME Drug resistance transporter Bcr/CflA subfamily Length = 426 Score = 402 bits (1032), Expect = e-110, Method: Compositional matrix adjust. Identities = 208/392 (53%), Positives = 267/392 (68%) Query: 1 MQNNDTSLSTGKFPAWLAVLAGLTAMGALAIDMYLPSFTAIAQDLGVGTNQVQLTLATFL 60 M + + S+ +FP WL + A LTA+ L+IDMYLPSF A+A DL QVQLTL TFL Sbjct: 19 MTSTKGAPSSSRFPLWLLICASLTAIAPLSIDMYLPSFPALAADLHTDIGQVQLTLGTFL 78 Query: 61 IGVAVGQMFYGPLSDRFGRKPPLFFGIALYFVCSLLCIFAQNIETLIVLRLFQGLGGSAG 120 +G+A+GQ FYGP+SDRFGRKPPL+ G+ +Y + C A +++L++ R Q LGG G Sbjct: 79 VGLAIGQAFYGPISDRFGRKPPLYVGLTIYGAAAAGCAMASTVDSLMLWRFLQALGGCTG 138 Query: 121 MVIPRAMVRDRMGAEGSAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGL 180 +V+ RA++RDRM A SA+A+S LMLV GLAPILAP IGG +L + WR IF + + Sbjct: 139 LVVSRAVIRDRMEAHESARAYSSLMLVMGLAPILAPLIGGAVLAASGWRAIFWIHCGAAV 198 Query: 181 LCILGTRKYLTETVDVSRAEPLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAG 240 L + + E++DV R LH LR YW LLR R+F+ Y L G VQ GMFAYIAG Sbjct: 199 LLLWFVHVRMEESLDVQRRRTLHPVAVLRSYWELLRDREFLGYSLAAGCVQGGMFAYIAG 258 Query: 241 GPFVVIELHGVKPQYFGFVFASNAIGLIAASQVNARLVVKRSAERVLGKVLWVPAGLSLT 300 PFV+IELHG+ P ++GFVF +NA GLI SQVN RLV R+ + VL L+ P L Sbjct: 259 SPFVLIELHGIDPSHYGFVFGANAFGLIGMSQVNTRLVRARALDDVLRVALFAPCVAGLV 318 Query: 301 VALLVLAGLETLPLLLLGFFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGSLQFGMG 360 +A L G TLP+LL+ FF FL+ G PNA+A+AL HQ +AGTA+ALMG+LQFG G Sbjct: 319 LAGTALIGWATLPVLLVCFFAFLSGLGCITPNASALALSHQSHRAGTASALMGTLQFGFG 378 Query: 361 VLSGVAMSLWHDGTALPLVSVMAVCGVTALLV 392 L+G A+SLWHDGTALPL VMAVCG A+++ Sbjct: 379 TLAGAAVSLWHDGTALPLAVVMAVCGSGAVVL 410 >B3RA15.1 B3RA15_CUPTR Bicyclomycin resistance protein ;Sulfonamide resistance protein; MFS family Length = 407 Score = 398 bits (1023), Expect = e-109, Method: Compositional matrix adjust. Identities = 214/402 (53%), Positives = 278/402 (69%) Query: 1 MQNNDTSLSTGKFPAWLAVLAGLTAMGALAIDMYLPSFTAIAQDLGVGTNQVQLTLATFL 60 M + ++ T +FPAWL + L A+ L+IDMYLPSF +A DLGV QVQLTL FL Sbjct: 1 MPHPASAAPTSRFPAWLLICGSLMAIAPLSIDMYLPSFPTLAGDLGVDIGQVQLTLGAFL 60 Query: 61 IGVAVGQMFYGPLSDRFGRKPPLFFGIALYFVCSLLCIFAQNIETLIVLRLFQGLGGSAG 120 +G+A+GQ FYGP SDRFGRKPPL+ G+ LY + ++ C A+N+E+L++ R Q LGG AG Sbjct: 61 VGLALGQAFYGPFSDRFGRKPPLYVGLCLYVLAAMGCALARNVESLMLWRFLQALGGCAG 120 Query: 121 MVIPRAMVRDRMGAEGSAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGL 180 MV+ RA++RDR+ A SA+AFS LMLV G+APILAP IGG +L + WR IF VL+ GL Sbjct: 121 MVMARAVIRDRLEAHESARAFSSLMLVMGVAPILAPIIGGAVLTVSGWRAIFWVLSGAGL 180 Query: 181 LCILGTRKYLTETVDVSRAEPLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAG 240 L +L + E++D A PL LG R Y LLR R+F+ Y L G AGMFAYI+G Sbjct: 181 LILLLVHLRMEESLDRRHAAPLRLGTVARSYAELLRDREFLGYSLSAGFGSAGMFAYISG 240 Query: 241 GPFVVIELHGVKPQYFGFVFASNAIGLIAASQVNARLVVKRSAERVLGKVLWVPAGLSLT 300 PFV+IELHG+ P ++GFVF +NA+GLI SQ+NARLV RS ++VLG L + Sbjct: 241 SPFVLIELHGIAPSHYGFVFGANALGLITMSQLNARLVRGRSLDQVLGATLLAALAAGMV 300 Query: 301 VALLVLAGLETLPLLLLGFFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGSLQFGMG 360 +A+ LAG+ LP+LL GFF F+ A G PNA+A+AL HQG +AGTA+ALMG+LQF +G Sbjct: 301 LAVAALAGMAVLPVLLGGFFVFIGALGCVSPNASALALAHQGHRAGTASALMGTLQFSLG 360 Query: 361 VLSGVAMSLWHDGTALPLVSVMAVCGVTALLVYHFAAKHAPA 402 L G A+S+W DG+ALPL VMA CG A+L+ H+ A A Sbjct: 361 TLGGAAVSVWRDGSALPLGVVMAACGAGAVLMRHYGRSGARA 402 >Q0K1V2.1 Q0K1V2_CUPNH MFS transporter, DHA1 family Length = 401 Score = 394 bits (1012), Expect = e-107, Method: Compositional matrix adjust. Identities = 211/395 (53%), Positives = 277/395 (70%) Query: 1 MQNNDTSLSTGKFPAWLAVLAGLTAMGALAIDMYLPSFTAIAQDLGVGTNQVQLTLATFL 60 M + ++ S +FPAWL + L A+ L+IDMYLPSF ++A DLGV QVQLTL TFL Sbjct: 1 MLRSTSAASAARFPAWLLICGSLMAIAPLSIDMYLPSFPSLAGDLGVDIGQVQLTLGTFL 60 Query: 61 IGVAVGQMFYGPLSDRFGRKPPLFFGIALYFVCSLLCIFAQNIETLIVLRLFQGLGGSAG 120 +G+A+GQ FYGP SDRFGRKPPL+ G+ LY ++ C A+++E+L++ R Q LGG AG Sbjct: 61 VGLALGQAFYGPFSDRFGRKPPLYVGLCLYVAAAVGCALARSVESLMLWRFLQALGGCAG 120 Query: 121 MVIPRAMVRDRMGAEGSAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGL 180 MV+ RA++RDR+ A SA+AFS LMLV G+APILAP +GG +L + WR IF VL + G+ Sbjct: 121 MVMARAVIRDRLEAHESARAFSSLMLVMGVAPILAPIVGGAILSVSGWRAIFWVLAVAGM 180 Query: 181 LCILGTRKYLTETVDVSRAEPLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAG 240 L +L + E++D A PL LG + Y LLR R+F+ Y L G AGMFAYI+G Sbjct: 181 LILLLVHLRMEESLDRRHAAPLRLGTVAKSYAELLRDREFLGYSLSAGFGSAGMFAYISG 240 Query: 241 GPFVVIELHGVKPQYFGFVFASNAIGLIAASQVNARLVVKRSAERVLGKVLWVPAGLSLT 300 PFV+IELHG+ P ++GFVF +NA+GLI SQ+NARLV RS ++VLG L L Sbjct: 241 SPFVLIELHGIAPSHYGFVFGANALGLITMSQLNARLVRGRSLDQVLGGALLAACAAGLA 300 Query: 301 VALLVLAGLETLPLLLLGFFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGSLQFGMG 360 +A+ LAG+ LP+LL GFF F+ A G PNA+A+AL HQG +AGTA+ALMG+LQF +G Sbjct: 301 LAVAALAGVAVLPVLLAGFFVFIGALGCVSPNASALALAHQGHRAGTASALMGTLQFSLG 360 Query: 361 VLSGVAMSLWHDGTALPLVSVMAVCGVTALLVYHF 395 L G A+SLW DGTALPL VMA CG A+L+ ++ Sbjct: 361 TLGGAAVSLWRDGTALPLGVVMAACGAGAVLMRYY 395 >Q46TZ2.1 Q46TZ2_CUPPJ Drug resistance transporter Bcr/CflA subfamily Length = 406 Score = 380 bits (977), Expect = e-103, Method: Compositional matrix adjust. Identities = 210/396 (53%), Positives = 278/396 (70%) Query: 1 MQNNDTSLSTGKFPAWLAVLAGLTAMGALAIDMYLPSFTAIAQDLGVGTNQVQLTLATFL 60 M + S +FPAWL + A LTA+ L+IDMYLPSF A+A D+ V Q+QLTL TFL Sbjct: 1 MPQSSRSQKAARFPAWLLICASLTAIAPLSIDMYLPSFPALAADMRVDIGQIQLTLGTFL 60 Query: 61 IGVAVGQMFYGPLSDRFGRKPPLFFGIALYFVCSLLCIFAQNIETLIVLRLFQGLGGSAG 120 +G+A+GQ FYGP+SDRFGRK PL+ G+ LY + + C A++ E+L++ R Q LGG AG Sbjct: 61 VGLALGQAFYGPISDRFGRKRPLYVGLGLYALAAAGCAMARSAESLMLWRFLQALGGCAG 120 Query: 121 MVIPRAMVRDRMGAEGSAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGL 180 MV+ RA++RDR+ A SA+AFS +MLV GLAPILAP IGG +L + WR IF +LTL GL Sbjct: 121 MVMARAVIRDRLDAHESARAFSSMMLVMGLAPILAPIIGGAILSASGWRAIFWLLTLAGL 180 Query: 181 LCILGTRKYLTETVDVSRAEPLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAG 240 L + + E++ RA PLH G + Y GLLR R+F+ Y L G QAGMFAYI+G Sbjct: 181 LILALVHFRMEESLPRERAAPLHPGAIVASYTGLLRDREFLGYSLSAGFGQAGMFAYISG 240 Query: 241 GPFVVIELHGVKPQYFGFVFASNAIGLIAASQVNARLVVKRSAERVLGKVLWVPAGLSLT 300 PFV+IEL+G+ P ++GFVF +NA+GLI SQ+NARLV R+ + VL + + P L Sbjct: 241 SPFVLIELNGIDPSHYGFVFGANALGLIGMSQLNARLVHGRTLDSVLRRAVLAPCAAGLI 300 Query: 301 VALLVLAGLETLPLLLLGFFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGSLQFGMG 360 +A LAG+ LP+LL GFF F+ + G PNA+A+AL HQG +AGTA+ALMG+LQF +G Sbjct: 301 LAAAALAGVLVLPVLLAGFFVFIGSLGCITPNASALALTHQGHRAGTASALMGTLQFSLG 360 Query: 361 VLSGVAMSLWHDGTALPLVSVMAVCGVTALLVYHFA 396 ++G A+SLWHDGTALPL VMA CG+ A+ + +A Sbjct: 361 TVAGAAVSLWHDGTALPLAVVMAACGMGAVALRAWA 396 >E4PI85.1 E4PI85_MARAH Drug resistance transporter, Bcr/CflA family protein Length = 398 Score = 364 bits (934), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 187/386 (48%), Positives = 256/386 (66%) Query: 13 FPAWLAVLAGLTAMGALAIDMYLPSFTAIAQDLGVGTNQVQLTLATFLIGVAVGQMFYGP 72 FP WL +LA LTA+ L++D+YLP+F AIA+ L V + Q+Q+TLA +L+G+AVGQ+ YGP Sbjct: 10 FPGWLFLLAMLTALSPLSVDLYLPAFPAIAESLNVNSAQIQVTLAAYLLGMAVGQLLYGP 69 Query: 73 LSDRFGRKPPLFFGIALYFVCSLLCIFAQNIETLIVLRLFQGLGGSAGMVIPRAMVRDRM 132 LSD FGRKPPL+FG+ALY + S C+FA ++ TL + R Q LGGS+G+VI RA++RDR Sbjct: 70 LSDHFGRKPPLYFGLALYVLASFACVFASDLTTLTIARFVQALGGSSGVVISRAVIRDRT 129 Query: 133 GAEGSAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGLLCILGTRKYLTE 192 SAKAFSMLML GLAPILAP +GG +L WRGIF VL + G++ + T + E Sbjct: 130 KPAQSAKAFSMLMLALGLAPILAPLLGGFLLYIMGWRGIFAVLGVTGIVLFISTHYSMRE 189 Query: 193 TVDVSRAEPLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAGGPFVVIELHGVK 252 T L L L +Y LLR QF YVL G++ GMFAY+AG PF+VIEL V Sbjct: 190 THFREPNAHLSLWSVLTRYLELLREWQFQKYVLVAGMLFGGMFAYVAGSPFIVIELFEVP 249 Query: 253 PQYFGFVFASNAIGLIAASQVNARLVVKRSAERVLGKVLWVPAGLSLTVALLVLAGLETL 312 P++FG+ F NAIG+IA SQ+NA L + E+VL V+W+P SL + ++L Sbjct: 250 PEHFGWFFGINAIGMIAGSQINANLATRYGPEKVLKHVIWIPFVASLLGFSSAVLQFDSL 309 Query: 313 PLLLLGFFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGSLQFGMGVLSGVAMSLWHD 372 PLL+L FF F+T+ G PNA A+A+ QG +AG+A+A+MG++QF +G L +S W Sbjct: 310 PLLMLCFFAFMTSMGLLSPNAMALAMASQGHRAGSASAIMGAIQFLIGTLGATVISFWPL 369 Query: 373 GTALPLVSVMAVCGVTALLVYHFAAK 398 +A+PL++VM + +L + K Sbjct: 370 PSAVPLMTVMLISTAGSLFFFLLGKK 395 >D8N9U3.1 D8N9U3_RALSO Putative bicyclomycin/multidrug efflux system (Major facilitator superfamily) Length = 407 Score = 362 bits (929), Expect = 5e-98, Method: Compositional matrix adjust. Identities = 189/389 (48%), Positives = 257/389 (66%), Gaps = 1/389 (0%) Query: 11 GKFPAWLAVLAGLTAMGALAIDMYLPSFTAIAQDLGVGTNQVQLTLATFLIGVAVGQMFY 70 G P WL +L LTA+G L++DMYLPS IA+DLG + +TL FL+ +A+GQ+ Y Sbjct: 16 GAIPGWLLLLGALTAIGPLSVDMYLPSLPTIARDLGTSSAAAGITLTAFLVSLAIGQLIY 75 Query: 71 GPLSDRFGRKPPLFFGIALYFVCSLLCIFAQNIETLIVLRLFQGLGGSAGMVIPRAMVRD 130 GP SDRFGRKPPL+ G+ALY S+ C FA + L VLR QG GG AGMVI RA VRD Sbjct: 76 GPASDRFGRKPPLYIGLALYVAASVGCAFATDATMLAVLRAVQGFGGCAGMVISRAAVRD 135 Query: 131 RMGAEGSAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGLLCILGTRKYL 190 RM G+A+A+S LMLV G+APILAP IGG +L SWR IF VL FG+L + + Sbjct: 136 RMDPAGAAQAYSTLMLVMGVAPILAPMIGGALLQMTSWRMIFAVLATFGVLSLAAVHFLM 195 Query: 191 TETVDVSRAEPLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAGGPFVVIELHG 250 E++D + A PL +GR LR YW LLR R + +Y CG + +GMFAYI PFV+I+ +G Sbjct: 196 RESLDAAHARPLAVGRVLRDYWELLRDRHYAAYTACGAVFVSGMFAYITASPFVLIDHYG 255 Query: 251 VKPQYFGFVFASNAIGLIAASQVNARLVVKRSAERVLGKVLWVPAGLSLTVALLVLAGLE 310 + P ++ +VF SNA G+IAAS++N RL+ + + RVL + LW+PA S+ A V AG Sbjct: 256 LSPSHYAWVFGSNAAGMIAASRINVRLMRRSTPARVLRRALWIPAATSVAAAAAVAAGFM 315 Query: 311 TLPLLLLGFFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGSLQFGMGVLSGVAMSLW 370 LPL+L F ++ + G PN A+A+ QG +AGT +ALMG++QFG+G+++G ++ + Sbjct: 316 PLPLVLAALFCYVASIGCISPNTGALAMAGQGARAGTGSALMGAMQFGLGMVTGTVVAAF 375 Query: 371 HDGTALPLVSVMAVCGVTALLVYHFAAKH 399 G A PL+ +MAV V AL + A +H Sbjct: 376 GQGAA-PLLGMMAVSAVLALWLGLRATQH 403 >D8P115.1 D8P115_RALSO Putative bicyclomycin/multidrug efflux system (Major facilitator superfamily) Length = 407 Score = 360 bits (925), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 189/389 (48%), Positives = 260/389 (66%), Gaps = 1/389 (0%) Query: 11 GKFPAWLAVLAGLTAMGALAIDMYLPSFTAIAQDLGVGTNQVQLTLATFLIGVAVGQMFY 70 G P WL +L LTA+G L+IDMYLPS +IA+DL + +TL FL+ +A+GQ+ Y Sbjct: 16 GAIPGWLLLLGALTAIGPLSIDMYLPSLPSIARDLDTSSAAAGITLTAFLVSLAIGQLIY 75 Query: 71 GPLSDRFGRKPPLFFGIALYFVCSLLCIFAQNIETLIVLRLFQGLGGSAGMVIPRAMVRD 130 GP SDRFGRKPPL+ G+ALY S+ C FA + L VLR QG GG AGMVI RA VRD Sbjct: 76 GPASDRFGRKPPLYIGLALYVAASIGCAFATDAMMLAVLRAVQGFGGCAGMVIARAAVRD 135 Query: 131 RMGAEGSAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGLLCILGTRKYL 190 RM G+A+A+S LMLV G+APILAP IGG +L SWR IF +L FG+L ++ + Sbjct: 136 RMDPAGAAQAYSTLMLVMGVAPILAPMIGGAVLQVTSWRMIFALLAAFGVLSLVAVHFLM 195 Query: 191 TETVDVSRAEPLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAGGPFVVIELHG 250 E++D +RA PL +GR LR YW LLR R + ++ CG + +GMFAYI PFV+I+ +G Sbjct: 196 RESLDPARARPLAVGRVLRDYWELLRDRHYAAHAACGAVFVSGMFAYITASPFVLIDHYG 255 Query: 251 VKPQYFGFVFASNAIGLIAASQVNARLVVKRSAERVLGKVLWVPAGLSLTVALLVLAGLE 310 + P ++ +VF SNA G+IAAS++N RLV + + RVL +VLW+PA S+ A+ V AG Sbjct: 256 LSPSHYAWVFGSNAAGMIAASRLNVRLVRRSAPARVLRRVLWIPAVTSVAAAVAVAAGFT 315 Query: 311 TLPLLLLGFFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGSLQFGMGVLSGVAMSLW 370 LPL+L F ++ + G PN A+A+ QG +AGT +AL+G++QFG+G+++G ++ Sbjct: 316 PLPLVLAALFCYVASIGCISPNTGALAMAGQGARAGTGSALLGAMQFGLGMVTGTVVAAI 375 Query: 371 HDGTALPLVSVMAVCGVTALLVYHFAAKH 399 A PL+ +MAVC V AL + A +H Sbjct: 376 GQAAA-PLLGMMAVCAVLALWLGLRATQH 403 >A3RR62.1 A3RR62_RALSO Transmembrane drug transport protein, MFS family Length = 407 Score = 360 bits (923), Expect = 3e-97, Method: Compositional matrix adjust. Identities = 190/381 (49%), Positives = 253/381 (66%), Gaps = 3/381 (0%) Query: 11 GKFPAWLAVLAGLTAMGALAIDMYLPSFTAIAQDLGVGTNQVQLTLATFLIGVAVGQMFY 70 G P WL +L LTA+G L++DMYLPS IA+DL + +TL FLI +A+GQ+ Y Sbjct: 16 GAIPGWLLLLGALTAIGPLSVDMYLPSLPTIARDLKTSSAAAGITLTAFLISLAIGQLIY 75 Query: 71 GPLSDRFGRKPPLFFGIALYFVCSLLCIFAQNIETLIVLRLFQGLGGSAGMVIPRAMVRD 130 GP SDRFGRKPPL+ G+ALY S+ C FA + TL VLR QG GG AGMVI RA VRD Sbjct: 76 GPASDRFGRKPPLYIGLALYVAASIGCAFAADAGTLAVLRAVQGFGGCAGMVISRAAVRD 135 Query: 131 RMGAEGSAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGLLCILGTRKYL 190 RM G+A+A+S LMLV G+APILAP IGG +L+ SWR IF VL FG+L + + Sbjct: 136 RMDPAGAAQAYSTLMLVMGVAPILAPMIGGAVLLVTSWRTIFAVLATFGVLSLAAVHFLM 195 Query: 191 TETVDVSRAEPLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAGGPFVVIELHG 250 E++D + PL GR LR YW LLR R + +Y++CG + +GMFAYI PFV+I+ +G Sbjct: 196 RESLDPAHVRPLAAGRVLRDYWELLRDRHYAAYMVCGAVFVSGMFAYITVSPFVLIDHYG 255 Query: 251 VKPQYFGFVFASNAIGLIAASQVNARLVVKRSAERVLGKVLWVPAGLSLTVALLVLAGLE 310 + P + +VF SNA G+IA S++N RLV + S RVL LW+P G S+ A+ V AG Sbjct: 256 LSPAQYAWVFGSNAAGMIAVSRINVRLVRRFSPARVLRGALWIPVGTSVAAAVAVAAGFT 315 Query: 311 TLPLLLLGFFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGSLQFGMGVLSG-VAMSL 369 LPL+L F ++ + G PN A+A+ QG +AGT +ALMG++QFG+G+++G V ++ Sbjct: 316 PLPLVLAALFCYVASIGCISPNTGALAMAGQGARAGTGSALMGAMQFGLGMVTGTVVAAI 375 Query: 370 WHDGTALPLVSVMAVCGVTAL 390 D A PL+ +MAVC V AL Sbjct: 376 GQD--AAPLLGMMAVCAVLAL 394 >Q8XXE2.1 Q8XXE2_RALSO Probable drug transport transmembrane protein Length = 407 Score = 357 bits (917), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 188/389 (48%), Positives = 257/389 (66%), Gaps = 1/389 (0%) Query: 11 GKFPAWLAVLAGLTAMGALAIDMYLPSFTAIAQDLGVGTNQVQLTLATFLIGVAVGQMFY 70 G P WL +L LTA+G L++DMYLPS IA+DL + +TL FL+ +A+GQ+ Y Sbjct: 16 GAIPGWLLLLGALTAIGPLSVDMYLPSLPTIARDLRTSSAAAGITLTAFLVSLAIGQLIY 75 Query: 71 GPLSDRFGRKPPLFFGIALYFVCSLLCIFAQNIETLIVLRLFQGLGGSAGMVIPRAMVRD 130 GP SDRFGRKPPL+ G+ALY S+ C FA + L VLR QG GG AGMVI RA VRD Sbjct: 76 GPASDRFGRKPPLYIGLALYVAASVGCAFATDATMLAVLRAVQGFGGCAGMVISRAAVRD 135 Query: 131 RMGAEGSAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTLFGLLCILGTRKYL 190 RM G+A+A+S LMLV G+APILAP IGG +L SWR IF VL FG+L + + Sbjct: 136 RMDPAGAAQAYSTLMLVMGVAPILAPMIGGAVLQVTSWRMIFAVLAAFGVLSLAAVHFLM 195 Query: 191 TETVDVSRAEPLHLGRTLRQYWGLLRHRQFMSYVLCGGLVQAGMFAYIAGGPFVVIELHG 250 E++D + A PL +GR LR YW LLR R + +Y CG + +GMFAYI PFV+I+ +G Sbjct: 196 RESLDAAHARPLAVGRVLRDYWELLRDRHYAAYTACGAVFVSGMFAYITASPFVLIDHYG 255 Query: 251 VKPQYFGFVFASNAIGLIAASQVNARLVVKRSAERVLGKVLWVPAGLSLTVALLVLAGLE 310 + P ++ +VF SNA G+IAAS++N RL+ + + RVL + LW+PA S+ A +V AG Sbjct: 256 LSPSHYAWVFGSNAAGMIAASRINVRLMRRSTPARVLRRALWMPAATSVAAAAVVGAGFM 315 Query: 311 TLPLLLLGFFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGSLQFGMGVLSGVAMSLW 370 LPL+L F ++ + G PN A+A+ QG +AGT +ALMG++QFG+G+++G ++ + Sbjct: 316 PLPLVLAALFCYVASIGCISPNTGALAMAGQGARAGTGSALMGAMQFGLGMVTGTVVAAF 375 Query: 371 HDGTALPLVSVMAVCGVTALLVYHFAAKH 399 G A PL+ +MAV V AL + A +H Sbjct: 376 GQGAA-PLLGMMAVSAVLALWLGLRATQH 403