BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0417.p (386 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IY41.1 D8IY41_HERSS Permease of the major facilitator superfam... 261 2e-67 A6SUD1.1 A6SUD1_JANMA Transporter of the MFS superfamily 134 2e-29 F1W441.1 F1W441_9BURK Major facilitator superfamily MFS1 131 2e-28 A4G1K7.1 A4G1K7_HERAR Putative Permease of the major facilitator... 130 4e-28 B1Y1K3.1 B1Y1K3_LEPCP Major facilitator superfamily MFS_1 77 5e-12 E5Y2Z5.1 E5Y2Z5_BILWA Major facilitator superfamily transporter 71 2e-10 C7PL77.1 C7PL77_CHIPD Major facilitator superfamily MFS_1 71 3e-10 D7C475.1 D7C475_STRBB Transmembrane transport protein 70 7e-10 D6KC37.1 D6KC37_9ACTO Putative uncharacterized protein 69 1e-09 D7BE62.1 D7BE62_MEISD Major facilitator superfamily MFS_1 69 1e-09 >D8IY41.1 D8IY41_HERSS Permease of the major facilitator superfamily protein Length = 400 Score = 261 bits (666), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 129/131 (98%), Positives = 129/131 (98%) Query: 1 MTTKHCIPALPQNHQAWRKIAIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLC 60 MTTKHCIPALPQNHQAWRKIAIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLC Sbjct: 16 MTTKHCIPALPQNHQAWRKIAIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLC 75 Query: 61 GGIGAVGSFPLAAWITGHYGARHSSLYAGLALLFSLPLLALAPGLWTLMAVCTLYGAASS 120 GGIGAVGSFPLAAWITGHYGARHSSLYAGL LL SLPLLALAPGLWTLMAVCTLYGAASS Sbjct: 76 GGIGAVGSFPLAAWITGHYGARHSSLYAGLVLLLSLPLLALAPGLWTLMAVCTLYGAASS 135 Query: 121 CFDVAINALGA 131 CFDVAINALGA Sbjct: 136 CFDVAINALGA 146 >A6SUD1.1 A6SUD1_JANMA Transporter of the MFS superfamily Length = 390 Score = 134 bits (337), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 75/147 (51%), Positives = 99/147 (67%), Gaps = 3/147 (2%) Query: 1 MTTKHCIPALPQNHQAWRKIAIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLC 60 M+T+ + P+ + R A PFLF+LLGV++++WAARIPAIRD LQL+ A L +VLL Sbjct: 7 MSTESLLSVAPRFAR-LRSAATPFLFILLGVIYASWAARIPAIRDALQLNPAQLGMVLLG 65 Query: 61 GGIGAVGSFPLAAWITGHYGARHSSLYAGLALLFSLPLLALAPGLWTLMAVCTLYGAASS 120 GG GAV SFPLAAW+ G +G R ++ Y+GL L+ LP LALAP + L+ V GA S Sbjct: 66 GGFGAVASFPLAAWLVGRFGGRRAAWYSGLGLIVVLPALALAPSMTWLVIVAVALGAGSG 125 Query: 121 CFDVAINALGAPRPSAKRAGPSCRCCM 147 CFDVAINA+G + K+AG S + Sbjct: 126 CFDVAINAIGTEQE--KQAGRSTMSLL 150 >F1W441.1 F1W441_9BURK Major facilitator superfamily MFS1 Length = 371 Score = 131 bits (329), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 100/248 (40%), Positives = 136/248 (54%), Gaps = 27/248 (10%) Query: 19 KIAIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLCGGIGAVGSFPLAAWITGH 78 +IA+P LF+LLG VF+TWAARIPA+RD LQL AA L LVLLC G+GAV SFPLAAW+ Sbjct: 5 RIALPILFILLGAVFATWAARIPALRDALQLGAAELGLVLLCSGVGAVLSFPLAAWLLAR 64 Query: 79 YGARHSSLYAGLALLFSLPLLALAPGLWTLMAVCTLYGAASSCFDVAINALGAPRPSAKR 138 +GARH++L++GLALL +P LALAP + LM G+A+SCFDVA+NA+GA + Sbjct: 65 HGARHAALWSGLALLMLVPCLALAPRMGWLMLAMFGMGSAASCFDVAVNAIGAEVE--RV 122 Query: 139 AGPS---------CRCCMAGS--ASAPSLVHWSPAPWPAWAWRRCGISCSRRR-CWPG-R 185 AG S C +G+ SA + +H +P W C +S W + Sbjct: 123 AGRSIMSMLHAWFCLGTFSGALLGSAMAGLHVTP------LWHFCLLSAGFLLPLWLSYQ 176 Query: 186 SMPVARPCPMTVRSTIRSASSSRCRMA-IWWCWA*SPFAAPSWKGRWPTGAAST*RTTSA 244 ++P R P VR + + I +C A + W G + T + A Sbjct: 177 ALPADRIVPGAVRQQFALPHGALVALGMIAFCGAMIEGSIGDWSGIYLTD-----QLGVA 231 Query: 245 PAMAPRPW 252 P +AP + Sbjct: 232 PGVAPLGY 239 >A4G1K7.1 A4G1K7_HERAR Putative Permease of the major facilitator superfamily Length = 384 Score = 130 bits (327), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 75/128 (58%), Positives = 90/128 (70%), Gaps = 4/128 (3%) Query: 21 AIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLCGGIGAVGSFPLAAWITGHYG 80 A PFLF+LLGV++++WAARIPAIRD LQL A L +VLL GG GAV SFPLAAW+ G +G Sbjct: 20 ATPFLFILLGVIYASWAARIPAIRDVLQLSPAQLGMVLLGGGFGAVASFPLAAWLVGRFG 79 Query: 81 ARHSSLYAGLALLFSLPLLALAPG-LWTLMAVCTLYGAASSCFDVAINALGAPRPSAKRA 139 R ++ YAGL L+ LP LALAP LW ++A L GAAS CFDVAINA+G K A Sbjct: 80 GRRAAWYAGLGLIVVLPALALAPNMLWLVIAAIVL-GAASGCFDVAINAIGTAHE--KLA 136 Query: 140 GPSCRCCM 147 G S + Sbjct: 137 GRSTMSLL 144 >B1Y1K3.1 B1Y1K3_LEPCP Major facilitator superfamily MFS_1 Length = 401 Score = 77.0 bits (188), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 44/106 (41%), Positives = 61/106 (57%) Query: 25 LFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLCGGIGAVGSFPLAAWITGHYGARHS 84 LF LGV+ W A IP+++ LD A+L+LVL C IGAV S +A + G GAR + Sbjct: 37 LFGALGVLGGVWGAHIPSLKSVYGLDEASLSLVLFCAAIGAVSSLFVAGRVIGRLGARRT 96 Query: 85 SLYAGLALLFSLPLLALAPGLWTLMAVCTLYGAASSCFDVAINALG 130 +L GL + + L P ++ LM C +G + S +DVAINA G Sbjct: 97 ALVTGLVMAAAQATALLWPSVYFLMFACLFFGTSMSIYDVAINAEG 142 >E5Y2Z5.1 E5Y2Z5_BILWA Major facilitator superfamily transporter Length = 380 Score = 71.2 bits (173), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 46/115 (40%), Positives = 67/115 (58%), Gaps = 6/115 (5%) Query: 14 HQAWRKIAIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLCGGIGAVGSFPLAA 73 Q +IA +L+LGV S+WAA +P + +L LD A L ++LLC G+G++ S P Sbjct: 15 EQITTRIA----YLVLGVGVSSWAALVPYAKARLGLDEAVLGMLLLCVGVGSLLSMPFTG 70 Query: 74 WITGHYGARHSSLYAGLALLFSLPLLALAPGLWTLMAVCT-LYGAASSCFDVAIN 127 I+G +G R L +G L LPLLA +W LMA+C L+GA+ DV++ Sbjct: 71 LISGRFGCRKVILVSGFIFLAMLPLLASVESVW-LMALCLFLFGASIGMMDVSLT 124 >C7PL77.1 C7PL77_CHIPD Major facilitator superfamily MFS_1 Length = 385 Score = 71.2 bits (173), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 45/123 (36%), Positives = 68/123 (55%), Gaps = 2/123 (1%) Query: 7 IPALPQNHQAWR--KIAIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLCGGIG 64 + L +H R +IA+ LF L G+ FS+WA+RIPAI+ +L L L +LL IG Sbjct: 2 LQELTVSHSQKRITRIAVSALFFLTGLCFSSWASRIPAIQHKLNLSEGELGGMLLALPIG 61 Query: 65 AVGSFPLAAWITGHYGARHSSLYAGLALLFSLPLLALAPGLWTLMAVCTLYGAASSCFDV 124 ++ S P+A + YG+R+ + AGL F LP L L W L + L+G + ++ Sbjct: 62 SILSMPVAGILVSRYGSRYVLMTAGLLYAFILPTLGLTSTAWQLFSCLILFGFCGNLANI 121 Query: 125 AIN 127 A+N Sbjct: 122 AVN 124 >D7C475.1 D7C475_STRBB Transmembrane transport protein Length = 435 Score = 69.7 bits (169), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 44/113 (38%), Positives = 65/113 (57%) Query: 19 KIAIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLCGGIGAVGSFPLAAWITGH 78 ++AI LF LG ++TWA+RIPA++ L L AA + +L+ G+GA SFPL + + Sbjct: 15 QLAIAALFCSLGFQYATWASRIPALKADLGLTAAEVGFLLMAAGVGASVSFPLVSVLMRR 74 Query: 79 YGARHSSLYAGLALLFSLPLLALAPGLWTLMAVCTLYGAASSCFDVAINALGA 131 G++ +L + L L L LA+AP +AV G C +VA+NA GA Sbjct: 75 LGSQRLALLSALGLTLVLIALAVAPNYPVALAVVCCDGVLVGCLNVAMNAQGA 127 >D6KC37.1 D6KC37_9ACTO Putative uncharacterized protein Length = 417 Score = 69.3 bits (168), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 45/112 (40%), Positives = 65/112 (58%), Gaps = 2/112 (1%) Query: 21 AIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLCGGIGAVGSFPLAAWITGHYG 80 AI LF LG ++TW AR+PA++ +L L + L+L+ G GA SFPL A + G Sbjct: 20 AIAALFCFLGFQYATWIARLPALKTRLDLGTGEVGLLLMACGAGAAASFPLVAVLMRRLG 79 Query: 81 ARHSSLYAGLALLFSLPLLALAPGL-WTLMAVCTLYGAASSCFDVAINALGA 131 +R +L + L+L+ L L++ P L+AVC G A C +VA+NA GA Sbjct: 80 SRRLALVSALSLVAVLAALSVVPNYPLALLAVCC-DGVAVGCLNVAMNAQGA 130 >D7BE62.1 D7BE62_MEISD Major facilitator superfamily MFS_1 Length = 391 Score = 68.9 bits (167), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 44/119 (36%), Positives = 66/119 (55%), Gaps = 1/119 (0%) Query: 10 LPQNHQAWRKIAIPFLFLLLGVVFSTWAARIPAIRDQLQLDAATLALVLLCGGIGAVGSF 69 LP++ A R +A+ F + G+VF+ W +RIPAI+++L LDAA L LVL +G + + Sbjct: 15 LPRSLAAAR-LAVYATFFVCGLVFAAWVSRIPAIKEKLGLDAAELGLVLFGAPMGLMVAL 73 Query: 70 PLAAWITGHYGARHSSLYAGLALLFSLPLLALAPGLWTLMAVCTLYGAASSCFDVAINA 128 P+ W G+ A L+ LP LALAP TL L+G + D+++NA Sbjct: 74 PVTGWAISRRGSHRVVTVAALSNCLVLPFLALAPSGVTLFVALFLFGFTQAALDISMNA 132