BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0393.p (258 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IY20.1 D8IY20_HERSS Exodeoxyribonuclease III protein EC=3.1.11.2 541 e-152 A6SUD3.1 A6SUD3_JANMA Exodeoxyribonuclease III EC=3.1.11.2 415 e-114 A4G1K9.1 A4G1K9_HERAR Putative Nuclease 414 e-114 F1W1U6.1 F1W1U6_9BURK Exodeoxyribonuclease III 407 e-112 Q3SM43.1 Q3SM43_THIDA DNA-(Apurinic or apyrimidinic site) lyase ... 394 e-108 C3XBT5.1 C3XBT5_OXAFO Exodeoxyribonuclease III 394 e-108 D9SHQ5.1 D9SHQ5_GALCS Exodeoxyribonuclease III Xth EC=4.2.99.18 390 e-106 Q476V7.1 Q476V7_CUPPJ AP endonuclease, family 1:Exodeoxyribonucl... 387 e-106 A1KBS4.1 A1KBS4_AZOSB Exodeoxyribonuclease III EC=3.1.11.2 387 e-105 C3X5L1.1 C3X5L1_OXAFO Exodeoxyribonuclease III 384 e-105 >D8IY20.1 D8IY20_HERSS Exodeoxyribonuclease III protein EC=3.1.11.2 Length = 258 Score = 541 bits (1393), Expect = e-152, Method: Compositional matrix adjust. Identities = 257/258 (99%), Positives = 258/258 (100%) Query: 1 MPKIVSANLNGIRSAAKKGFFEWLQKEAPDFVCVQELKAQAADMTEQFLAPAGYVGHFHY 60 MPKIVSANLNGIRSAAKKGFFEWLQKEAPDFVCVQELKAQAADMTEQFLAPAGYVGHFHY Sbjct: 1 MPKIVSANLNGIRSAAKKGFFEWLQKEAPDFVCVQELKAQAADMTEQFLAPAGYVGHFHY 60 Query: 61 AQKKGYSGVGVYSRRQPDSVRIGFGNTEFDDEGRYVECDYGDLTVISLYAPSGSSSEERQ 120 AQKKGYSGVGVYSRRQPDSVRIGFGNTEFDDEGRYVECDYGDLTVISLYAPSGSSSEERQ Sbjct: 61 AQKKGYSGVGVYSRRQPDSVRIGFGNTEFDDEGRYVECDYGDLTVISLYAPSGSSSEERQ 120 Query: 121 EAKFRFMEAFLPHLMELEQSGREVVICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAWMT 180 EAKFRFMEAFLPHLMELE+SGREVVICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAWMT Sbjct: 121 EAKFRFMEAFLPHLMELEKSGREVVICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAWMT 180 Query: 181 RIFDQLGLVDVYRRLHPETTGEAYTWWSNRGQAWANNVGWRIDYHVSTPGIAAKAVSAAI 240 RIFDQLGLVDVYRRLHPETTGEAYTWWSNRGQAWANNVGWRIDYHVSTPGIAAKAVSAAI Sbjct: 181 RIFDQLGLVDVYRRLHPETTGEAYTWWSNRGQAWANNVGWRIDYHVSTPGIAAKAVSAAI 240 Query: 241 YKEQRFSDHAPLTVVYSD 258 YKEQRFSDHAPLTVVYSD Sbjct: 241 YKEQRFSDHAPLTVVYSD 258 >A6SUD3.1 A6SUD3_JANMA Exodeoxyribonuclease III EC=3.1.11.2 Length = 259 Score = 415 bits (1066), Expect = e-114, Method: Compositional matrix adjust. Identities = 190/256 (74%), Positives = 219/256 (85%) Query: 1 MPKIVSANLNGIRSAAKKGFFEWLQKEAPDFVCVQELKAQAADMTEQFLAPAGYVGHFHY 60 M KIVSANLNGIRSAAKKGFF W+ K DF+CVQELKAQA DMT +FL P GY G+FHY Sbjct: 1 MLKIVSANLNGIRSAAKKGFFTWMAKHDADFICVQELKAQAPDMTPEFLTPPGYTGYFHY 60 Query: 61 AQKKGYSGVGVYSRRQPDSVRIGFGNTEFDDEGRYVECDYGDLTVISLYAPSGSSSEERQ 120 A+KKGYSG GVY + PD V+IGFG +EFD EGRYV+CD+G L+VIS+Y PSGSSSEERQ Sbjct: 61 AEKKGYSGAGVYCKTVPDHVQIGFGCSEFDAEGRYVQCDFGKLSVISVYCPSGSSSEERQ 120 Query: 121 EAKFRFMEAFLPHLMELEQSGREVVICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAWMT 180 AKFRFM+ FLPHL+EL+ GR+ VICGDWNIAH EIDLKN+K N+KNSGFLPEERAW++ Sbjct: 121 LAKFRFMDVFLPHLLELKAQGRDFVICGDWNIAHNEIDLKNFKGNRKNSGFLPEERAWLS 180 Query: 181 RIFDQLGLVDVYRRLHPETTGEAYTWWSNRGQAWANNVGWRIDYHVSTPGIAAKAVSAAI 240 R+FD++GLVDVYRRLHP TT E YTWWSNRGQA+A NVGWRIDY V+TP +A A SAAI Sbjct: 181 RVFDEVGLVDVYRRLHPTTTEECYTWWSNRGQAYAKNVGWRIDYQVATPALAETARSAAI 240 Query: 241 YKEQRFSDHAPLTVVY 256 YK++RFSDHAPLT+ Y Sbjct: 241 YKDERFSDHAPLTIDY 256 >A4G1K9.1 A4G1K9_HERAR Putative Nuclease Length = 259 Score = 414 bits (1064), Expect = e-114, Method: Compositional matrix adjust. Identities = 186/257 (72%), Positives = 221/257 (85%) Query: 1 MPKIVSANLNGIRSAAKKGFFEWLQKEAPDFVCVQELKAQAADMTEQFLAPAGYVGHFHY 60 M KIVSANLNGIRSAAKKGFF+W+ + + D++CVQELKAQ ADMT FL P GY G+FHY Sbjct: 1 MLKIVSANLNGIRSAAKKGFFQWMARHSADYICVQELKAQEADMTPDFLTPEGYFGYFHY 60 Query: 61 AQKKGYSGVGVYSRRQPDSVRIGFGNTEFDDEGRYVECDYGDLTVISLYAPSGSSSEERQ 120 A+KKGYSG GVY + +PD+V+IGF EFD EGRYV+CD+G+L+VIS+Y PSGSS EERQ Sbjct: 61 AEKKGYSGAGVYCKTKPDNVQIGFNCPEFDAEGRYVQCDFGNLSVISVYCPSGSSGEERQ 120 Query: 121 EAKFRFMEAFLPHLMELEQSGREVVICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAWMT 180 +AKFRFM+ FLPHL+EL+ GRE VICGDWNIAH EIDLKN+K N+KNSGFLPEER W+T Sbjct: 121 QAKFRFMDVFLPHLLELKSQGREFVICGDWNIAHNEIDLKNYKGNRKNSGFLPEEREWLT 180 Query: 181 RIFDQLGLVDVYRRLHPETTGEAYTWWSNRGQAWANNVGWRIDYHVSTPGIAAKAVSAAI 240 R+FD++GLVDVYRRLHP TT E YTWWSNRGQA+A NVGWRIDY V+TP +AA+A +A I Sbjct: 181 RVFDEVGLVDVYRRLHPGTTEECYTWWSNRGQAYAKNVGWRIDYQVATPSLAARAHAAEI 240 Query: 241 YKEQRFSDHAPLTVVYS 257 YK +RFSDHAPLT+ Y+ Sbjct: 241 YKVERFSDHAPLTITYT 257 >F1W1U6.1 F1W1U6_9BURK Exodeoxyribonuclease III Length = 256 Score = 407 bits (1047), Expect = e-112, Method: Compositional matrix adjust. Identities = 185/256 (72%), Positives = 220/256 (85%), Gaps = 2/256 (0%) Query: 1 MPKIVSANLNGIRSAAKKGFFEWLQKEAPDFVCVQELKAQAADMTEQFLAPAGYVGHFHY 60 M KI++ANLNGIRSA+KKGFFEW+ K+ DF+CVQELKAQAADM+ + LAP GY G+FHY Sbjct: 1 MLKIIAANLNGIRSASKKGFFEWMAKQDADFICVQELKAQAADMSPEMLAPEGYHGYFHY 60 Query: 61 AQKKGYSGVGVYSRRQPDSVRIGFGNTEFDDEGRYVECDYGDLTVISLYAPSGSSSEERQ 120 A+KKGYSG GVYS+R PD V GFG EFD EGRYV+CDYG+L+++S+Y PSGSS EERQ Sbjct: 61 AEKKGYSGTGVYSKRVPDQVITGFGTPEFDAEGRYVQCDYGNLSIVSVYCPSGSSGEERQ 120 Query: 121 EAKFRFMEAFLPHLMELEQSGREVVICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAWMT 180 AKFRFM+ FLPHL L+ SGREVVICGDWNIAH+EIDLKNWK N+KNSGFLPEERAW++ Sbjct: 121 LAKFRFMDVFLPHLAALKASGREVVICGDWNIAHQEIDLKNWKGNKKNSGFLPEERAWLS 180 Query: 181 RIFDQLGLVDVYRRLHPETTGEAYTWWSNRGQAWANNVGWRIDYHVSTPGIAAKAVSAAI 240 R+FD++ LVDV+RR+ + E YTWWSNRGQAWANNVGWRIDY ++TPGIAA A + AI Sbjct: 181 RLFDEVALVDVFRRV--DERAEQYTWWSNRGQAWANNVGWRIDYQIATPGIAATAKAVAI 238 Query: 241 YKEQRFSDHAPLTVVY 256 YK++RFSDHAPLT+ Y Sbjct: 239 YKDERFSDHAPLTIEY 254 >Q3SM43.1 Q3SM43_THIDA DNA-(Apurinic or apyrimidinic site) lyase EC=4.2.99.18 Length = 259 Score = 394 bits (1013), Expect = e-108, Method: Compositional matrix adjust. Identities = 185/254 (72%), Positives = 210/254 (82%) Query: 3 KIVSANLNGIRSAAKKGFFEWLQKEAPDFVCVQELKAQAADMTEQFLAPAGYVGHFHYAQ 62 +I+SANLNGIRSAA KGFF+WL + D VCVQELKAQA D+ + G G FH A+ Sbjct: 2 RIISANLNGIRSAATKGFFDWLPTQGADVVCVQELKAQATDLKPEVRQCDGLSGAFHCAE 61 Query: 63 KKGYSGVGVYSRRQPDSVRIGFGNTEFDDEGRYVECDYGDLTVISLYAPSGSSSEERQEA 122 KKGYSGVGVY+R+ P + G G EFD EGRY+E DYGDL VISLY PSGSSSEERQ+A Sbjct: 62 KKGYSGVGVYTRQAPQRIVEGLGLPEFDAEGRYIEADYGDLAVISLYQPSGSSSEERQQA 121 Query: 123 KFRFMEAFLPHLMELEQSGREVVICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAWMTRI 182 KFRF++AF PHL +L + GRE++ICGDWNIAH+EIDLKNWKSNQKNSGFLPEERAWMTR+ Sbjct: 122 KFRFLDAFFPHLEKLVKCGREIIICGDWNIAHQEIDLKNWKSNQKNSGFLPEERAWMTRL 181 Query: 183 FDQLGLVDVYRRLHPETTGEAYTWWSNRGQAWANNVGWRIDYHVSTPGIAAKAVSAAIYK 242 FD+LG VDVYR L+P TGEAYTWWSNRGQAWA NVGWRIDY ++TPGIAAKA SA +YK Sbjct: 182 FDELGWVDVYRSLYPAHTGEAYTWWSNRGQAWAKNVGWRIDYQIATPGIAAKARSAFVYK 241 Query: 243 EQRFSDHAPLTVVY 256 EQRFSDHAPL V Y Sbjct: 242 EQRFSDHAPLVVDY 255 >C3XBT5.1 C3XBT5_OXAFO Exodeoxyribonuclease III Length = 260 Score = 394 bits (1011), Expect = e-108, Method: Compositional matrix adjust. Identities = 178/256 (69%), Positives = 211/256 (82%) Query: 1 MPKIVSANLNGIRSAAKKGFFEWLQKEAPDFVCVQELKAQAADMTEQFLAPAGYVGHFHY 60 M I S NLNGIRSA KKGF +W+ + DFVC+QE+KAQ+ D+T + P GY G+F Sbjct: 1 MFSITSVNLNGIRSAVKKGFLDWMNRSGSDFVCLQEIKAQSCDITPEVATPDGYQGYFEC 60 Query: 61 AQKKGYSGVGVYSRRQPDSVRIGFGNTEFDDEGRYVECDYGDLTVISLYAPSGSSSEERQ 120 A+KKGYSG G+Y++ PD + GFG+ EFD EGRY +CD+ D +++SLYAPSGSSS ERQ Sbjct: 61 AEKKGYSGTGIYTKTMPDKIENGFGSKEFDAEGRYFQCDFRDFSLVSLYAPSGSSSPERQ 120 Query: 121 EAKFRFMEAFLPHLMELEQSGREVVICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAWMT 180 EAKFRFM+ F P+L +L+ SGRE VICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAW+T Sbjct: 121 EAKFRFMDEFYPYLKKLKDSGREFVICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAWLT 180 Query: 181 RIFDQLGLVDVYRRLHPETTGEAYTWWSNRGQAWANNVGWRIDYHVSTPGIAAKAVSAAI 240 +FD+LG VDVYR LHP+TTGEAYTWWSNRGQA+A NVGWRIDY ++TPGIA KAVSA I Sbjct: 181 DVFDELGWVDVYRLLHPDTTGEAYTWWSNRGQAYAKNVGWRIDYQIATPGIAKKAVSADI 240 Query: 241 YKEQRFSDHAPLTVVY 256 YK +RFSDHAPLT+ Y Sbjct: 241 YKGERFSDHAPLTIRY 256 >D9SHQ5.1 D9SHQ5_GALCS Exodeoxyribonuclease III Xth EC=4.2.99.18 Length = 254 Score = 390 bits (1002), Expect = e-106, Method: Compositional matrix adjust. Identities = 176/254 (69%), Positives = 210/254 (82%), Gaps = 2/254 (0%) Query: 3 KIVSANLNGIRSAAKKGFFEWLQKEAPDFVCVQELKAQAADMTEQFLAPAGYVGHFHYAQ 62 +I+S NLNGIRSA+ KGF+EWL ++ D +C+QELKAQAADMTE L P GY G+FHYA+ Sbjct: 2 RIISVNLNGIRSASSKGFYEWLAQQDADVICLQELKAQAADMTEHMLTPLGYHGYFHYAE 61 Query: 63 KKGYSGVGVYSRRQPDSVRIGFGNTEFDDEGRYVECDYGDLTVISLYAPSGSSSEERQEA 122 KKGYSGVG+Y R P +V +G G +FD EGRY+ D+ D +V+SLY PSGSS EERQ Sbjct: 62 KKGYSGVGIYCRELPKNVIVGLGIEQFDAEGRYLCADFADYSVVSLYLPSGSSGEERQGV 121 Query: 123 KFRFMEAFLPHLMELEQSGREVVICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAWMTRI 182 KF FMEAFLPHL EL SGREV++CGDWNIAHKEIDLKNW+ N+KNSGFLPEERAW+T++ Sbjct: 122 KFSFMEAFLPHLRELRASGREVIVCGDWNIAHKEIDLKNWRGNKKNSGFLPEERAWLTQL 181 Query: 183 FDQLGLVDVYRRLHPETTGEAYTWWSNRGQAWANNVGWRIDYHVSTPGIAAKAVSAAIYK 242 FD++G VDV+RR+HPE EAYTWWSNRGQAWA NVGWRIDY ++TP IA +A SA+IYK Sbjct: 182 FDEVGFVDVFRRVHPEL--EAYTWWSNRGQAWAKNVGWRIDYQIATPAIAGRATSASIYK 239 Query: 243 EQRFSDHAPLTVVY 256 EQRFSDHAPL + Y Sbjct: 240 EQRFSDHAPLIIDY 253 >Q476V7.1 Q476V7_CUPPJ AP endonuclease, family 1:Exodeoxyribonuclease III xth EC=4.2.99.18 Length = 258 Score = 387 bits (995), Expect = e-106, Method: Compositional matrix adjust. Identities = 181/257 (70%), Positives = 215/257 (83%), Gaps = 2/257 (0%) Query: 1 MPKIVSANLNGIRSAAKKGFFEWLQKEAPDFVCVQELKAQAADMTEQFLAPAGYVGHFHY 60 M +I+SANLNGIRSA+KKGFFEW+ K+ D VCVQELKAQAADMTE FLAP GY G+FHY Sbjct: 1 MLRIISANLNGIRSASKKGFFEWMGKQDADMVCVQELKAQAADMTEAFLAPHGYHGYFHY 60 Query: 61 AQKKGYSGVGVYSRRQPDSVRIGFGNTEFDDEGRYVECDYGDLTVISLYAPSGSSSEERQ 120 A+KKGYSGVG+Y+R +P+ V GFGN EFD EGRYVE Y L VIS+Y PSGSSSEERQ Sbjct: 61 AEKKGYSGVGLYTRHKPERVITGFGNPEFDSEGRYVEVQYPHLAVISVYVPSGSSSEERQ 120 Query: 121 EAKFRFMEAFLPHLMELEQSGREVVICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAWMT 180 +AKFRFMEAFLPHL++L+ SGRE+V+CGD NIAHKEID+KNWK N KNSGFLPEERAW+ Sbjct: 121 QAKFRFMEAFLPHLLQLKASGREIVLCGDVNIAHKEIDIKNWKGNLKNSGFLPEERAWIG 180 Query: 181 RIFDQLGLVDVYRRLHPETTGEAYTWWSNRGQAWANNVGWRIDYHVSTPGIAAKAVSAAI 240 ++FD G VDV+R+L P E YTWWSNRGQA+A NVGWRIDYH++TP IA A +I Sbjct: 181 QLFDMHGYVDVFRQLDPRP--EQYTWWSNRGQAYAKNVGWRIDYHLATPKIAGTAHVCSI 238 Query: 241 YKEQRFSDHAPLTVVYS 257 YK+++FSDHAPL++ Y+ Sbjct: 239 YKDEKFSDHAPLSIDYN 255 >A1KBS4.1 A1KBS4_AZOSB Exodeoxyribonuclease III EC=3.1.11.2 Length = 260 Score = 387 bits (993), Expect = e-105, Method: Compositional matrix adjust. Identities = 179/256 (69%), Positives = 209/256 (81%) Query: 1 MPKIVSANLNGIRSAAKKGFFEWLQKEAPDFVCVQELKAQAADMTEQFLAPAGYVGHFHY 60 M +I+SANLNGIRSA KGF +WL + D VCVQELKAQA D+T+ APAGY G FHY Sbjct: 1 MLRIISANLNGIRSATTKGFLDWLPAQNADVVCVQELKAQAGDLTDAMRAPAGYQGWFHY 60 Query: 61 AQKKGYSGVGVYSRRQPDSVRIGFGNTEFDDEGRYVECDYGDLTVISLYAPSGSSSEERQ 120 A+KKGYSGVG+YSR+ PD V G G + D EGRY++ D+G L+VISLY PSGSSSEERQ Sbjct: 61 AEKKGYSGVGIYSRKAPDRVVEGLGIADIDAEGRYLQADFGALSVISLYLPSGSSSEERQ 120 Query: 121 EAKFRFMEAFLPHLMELEQSGREVVICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAWMT 180 +AKF FME F+P L EL + G+EVVICGDWNIAH+EIDLKNWKSNQKNSGFLPEERAW+ Sbjct: 121 QAKFSFMERFMPRLAELRRCGQEVVICGDWNIAHREIDLKNWKSNQKNSGFLPEERAWIG 180 Query: 181 RIFDQLGLVDVYRRLHPETTGEAYTWWSNRGQAWANNVGWRIDYHVSTPGIAAKAVSAAI 240 +FD G VDVYR L+PE TG++YTWWSNRGQAWA NVGWRIDY ++TPGIAA+A + ++ Sbjct: 181 TLFDTHGWVDVYRALYPEATGDSYTWWSNRGQAWAKNVGWRIDYQIATPGIAARARAGSV 240 Query: 241 YKEQRFSDHAPLTVVY 256 YK QRFSDHAPL V Y Sbjct: 241 YKAQRFSDHAPLVVDY 256 >C3X5L1.1 C3X5L1_OXAFO Exodeoxyribonuclease III Length = 260 Score = 384 bits (985), Expect = e-105, Method: Compositional matrix adjust. Identities = 176/256 (68%), Positives = 208/256 (81%) Query: 1 MPKIVSANLNGIRSAAKKGFFEWLQKEAPDFVCVQELKAQAADMTEQFLAPAGYVGHFHY 60 M I +ANLNGIRSA +KGF EW+ + FVCVQE+KAQ D+ +P + GHF Sbjct: 1 MFSITTANLNGIRSAVRKGFLEWMHQSGSHFVCVQEIKAQPDDIVPAIASPDLFHGHFGC 60 Query: 61 AQKKGYSGVGVYSRRQPDSVRIGFGNTEFDDEGRYVECDYGDLTVISLYAPSGSSSEERQ 120 A+KKGYSGVG+YS+ +PD V GFG EFD EGRY++CDY D +++SLYAPSGSSS ERQ Sbjct: 61 AEKKGYSGVGIYSKTKPDKVIRGFGCPEFDAEGRYLQCDYKDFSLVSLYAPSGSSSPERQ 120 Query: 121 EAKFRFMEAFLPHLMELEQSGREVVICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAWMT 180 EAKFRFM+ F P L +L++S RE +ICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAW++ Sbjct: 121 EAKFRFMDHFFPFLEKLKESEREFIICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAWLS 180 Query: 181 RIFDQLGLVDVYRRLHPETTGEAYTWWSNRGQAWANNVGWRIDYHVSTPGIAAKAVSAAI 240 RI D+LGL+DVYR LHP+TT +YTWWSNRGQAW NVGWRIDY ++TPGIA KAVSA+I Sbjct: 181 RILDELGLIDVYRCLHPDTTDASYTWWSNRGQAWQKNVGWRIDYQIATPGIAGKAVSASI 240 Query: 241 YKEQRFSDHAPLTVVY 256 YKE RFSDHAPLT+ Y Sbjct: 241 YKETRFSDHAPLTIWY 256