BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0345.p (491 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IXY0.1 D8IXY0_HERSS Transmembrane protein 968 0.0 D8ISU7.1 D8ISU7_HERSS Transmembrane protein 615 e-174 D8IWS9.1 D8IWS9_HERSS Transmembrane protein 427 e-117 B4EA36.1 B4EA36_BURCJ Putative diguanylate cyclase 357 3e-96 Q1BH63.1 Q1BH63_BURCA Diguanylate cyclase 348 1e-93 A0K825.1 A0K825_BURCH Diguanylate cyclase 348 1e-93 A2VXN5.1 A2VXN5_9BURK Diguanylate cyclase (GGDEF domain) 346 4e-93 A4JS67.1 A4JS67_BURVG Diguanylate cyclase 345 7e-93 B1YVN5.1 B1YVN5_BURA4 Diguanylate cyclase 345 9e-93 A4JS04.1 A4JS04_BURVG Diguanylate cyclase 345 1e-92 >D8IXY0.1 D8IXY0_HERSS Transmembrane protein Length = 515 Score = 968 bits (2503), Expect = 0.0, Method: Compositional matrix adjust. Identities = 477/488 (97%), Positives = 481/488 (98%) Query: 1 LKNYLVVILAIAVLMVMAISASTLYQSYQQTRQSAVSNASNVTLVSQRAISRNREMLSLS 60 LKNYLVVILAIAVLMVMAISASTLYQSYQQTRQSAVSNASNVTLVSQRAISRN EMLSLS Sbjct: 25 LKNYLVVILAIAVLMVMAISASTLYQSYQQTRQSAVSNASNVTLVSQRAISRNLEMLSLS 84 Query: 61 LDTLAYRFQHPLSARRLNDAQRYAYLFGSTTNVSHIAVMAVLDADGRVQVSSRLGRGKGA 120 LDTLAYRFQHPLSARRLNDAQRYAYLFGSTTNVSHIAVMAVLDADGRVQVSSRLGRG GA Sbjct: 85 LDTLAYRFQHPLSARRLNDAQRYAYLFGSTTNVSHIAVMAVLDADGRVQVSSRLGRGNGA 144 Query: 121 PHYADRAYFIAHRDSPTVGLYVSRPMQASLGNELQVVVLSKRLSNEDGSFAGVVVMALDL 180 PHYADRAYFIAHRDSPTVGLYVSRPMQASLGNELQVVVLSKRLSNEDGSFAGVVVMALDL Sbjct: 145 PHYADRAYFIAHRDSPTVGLYVSRPMQASLGNELQVVVLSKRLSNEDGSFAGVVVMALDL 204 Query: 181 AYFRELFEGLALGDEGIISLYSDEGIAYMRVPYRETIIGRDVSQTGNFQRLRAMLSEEEG 240 AYFRELFEGLALGDEGIISLYSDEGIAYMRVPYRETIIGRD+SQTGNFQRLRAMLSEEEG Sbjct: 205 AYFRELFEGLALGDEGIISLYSDEGIAYMRVPYRETIIGRDISQTGNFQRLRAMLSEEEG 264 Query: 241 SFFAHATNDGVRRLYTFRRIPGSPLIVFVGYAEEAIFKTWRKTFYAVLVSLAIFGLLTVW 300 SFFAHATNDGVRRLYTFRRIPGSPLIVFVGYAEEAIFKTWRKTFYAVLVSLAIFGLLT W Sbjct: 265 SFFAHATNDGVRRLYTFRRIPGSPLIVFVGYAEEAIFKTWRKTFYAVLVSLAIFGLLTAW 324 Query: 301 LLLHVRQELRRRVTAERQLEALARTDGLTGLLNRRALDEALQATWERCQRNLGASFSVLF 360 LLLHVRQELRRRVTAERQLEALARTDGLT LLNRRALDEALQATWERCQRNLGASFSVLF Sbjct: 325 LLLHVRQELRRRVTAERQLEALARTDGLTDLLNRRALDEALQATWERCQRNLGASFSVLF 384 Query: 361 IDVDYFKAYNDTYGHKLGDTVLKEVAATLTARLPRHTDCAGRYGGEEFVVLLEQTDLQGA 420 IDVDYFKAYNDTYGHKLGDTVLKEVAATLTARLPRHTDCAGRYGGEEFVVLLEQTDLQGA Sbjct: 385 IDVDYFKAYNDTYGHKLGDTVLKEVAATLTARLPRHTDCAGRYGGEEFVVLLEQTDLQGA 444 Query: 421 QMMAQRLCDAVRERHIAHTSSPLAVVTISVGVATLERDHHRRVEDVLNAADAALYRAKRE 480 QMMAQRLCDAVRERHIAHTSSPLAVVTISVGVATLERDHHRRVEDVLNAADAALYRAK+ Sbjct: 445 QMMAQRLCDAVRERHIAHTSSPLAVVTISVGVATLERDHHRRVEDVLNAADAALYRAKQA 504 Query: 481 GRNAVRVS 488 GR+ V +S Sbjct: 505 GRDRVHLS 512 >D8ISU7.1 D8ISU7_HERSS Transmembrane protein Length = 501 Score = 615 bits (1585), Expect = e-174, Method: Compositional matrix adjust. Identities = 301/489 (61%), Positives = 378/489 (77%), Gaps = 1/489 (0%) Query: 1 LKNYLVVILAIAVLMVMAISASTLYQSYQQTRQSAVSNASNVTLVSQRAISRNREMLSLS 60 L+ YL +IL + ++MV++I ++LY+ Y+QTR SA++ A+NVTL+ QRAISRN E+LSL+ Sbjct: 4 LQKYLALILGLIIMMVLSICGASLYEGYRQTRISAITEANNVTLIVQRAISRNMEILSLA 63 Query: 61 LDTLAYRFQHPLSARRLNDAQRYAYLFGSTTNVSHIAVMAVLDADGRVQVSSRLGRGKGA 120 +DTLAYR+QHPL +D +RY YLFGST HI +A+LDADG V+V+SR Sbjct: 64 MDTLAYRYQHPLDLTHASDEERYNYLFGSTAAAHHITALAILDADGYVRVTSRRSASPSV 123 Query: 121 P-HYADRAYFIAHRDSPTVGLYVSRPMQASLGNELQVVVLSKRLSNEDGSFAGVVVMALD 179 +Y++R YF HRDS GL++SRP++A+LGNEL VVVLSKRLS +DGSF GVV+MALD Sbjct: 124 VVNYSERTYFTVHRDSADAGLFISRPIKANLGNELPVVVLSKRLSRKDGSFDGVVLMALD 183 Query: 180 LAYFRELFEGLALGDEGIISLYSDEGIAYMRVPYRETIIGRDVSQTGNFQRLRAMLSEEE 239 ++YFR+LF GL LG++GI+SLYSD+G+ YMRVPY + IGR+++ NFQRLRAML + + Sbjct: 184 MSYFRDLFTGLTLGEDGIMSLYSDDGVTYMRVPYHPSSIGREITNNPNFQRLRAMLVDND 243 Query: 240 GSFFAHATNDGVRRLYTFRRIPGSPLIVFVGYAEEAIFKTWRKTFYAVLVSLAIFGLLTV 299 G+FFA A DGV RLYTFRRIP +PLIV +G +E IFKTW T Y+VL+ L IF L Sbjct: 244 GNFFARAHTDGVERLYTFRRIPDAPLIVLLGRSERFIFKTWYDTLYSVLLLLIIFTALAG 303 Query: 300 WLLLHVRQELRRRVTAERQLEALARTDGLTGLLNRRALDEALQATWERCQRNLGASFSVL 359 LL+ VR+EL +RV AE+QLE LARTDGLTGLLNRR+LDEAL A W+R QR+ A FS L Sbjct: 304 VLLMLVRRELLKRVAAEKQLEDLARTDGLTGLLNRRSLDEALLAVWQRSQRSPTAGFSTL 363 Query: 360 FIDVDYFKAYNDTYGHKLGDTVLKEVAATLTARLPRHTDCAGRYGGEEFVVLLEQTDLQG 419 FIDVDYFK YNDTYGH++GDTVL+ VAA L L R D AGRYGGEEFVVLLEQTD G Sbjct: 364 FIDVDYFKRYNDTYGHEMGDTVLQAVAAVLREHLQRQNDLAGRYGGEEFVVLLEQTDEHG 423 Query: 420 AQMMAQRLCDAVRERHIAHTSSPLAVVTISVGVATLERDHHRRVEDVLNAADAALYRAKR 479 A MAQ+LC+A+ R I H+ SPL V+++S+GVAT+ R H+R+EDVLNAAD ALY AKR Sbjct: 424 ALRMAQQLCEAIYNRGIPHSGSPLGVISVSIGVATMNRAPHQRMEDVLNAADHALYIAKR 483 Query: 480 EGRNAVRVS 488 EGRN V V+ Sbjct: 484 EGRNRVCVA 492 >D8IWS9.1 D8IWS9_HERSS Transmembrane protein Length = 475 Score = 427 bits (1099), Expect = e-117, Method: Compositional matrix adjust. Identities = 217/473 (45%), Positives = 311/473 (65%), Gaps = 6/473 (1%) Query: 15 MVMAISASTLYQSYQQTRQSAVSNASNVTLVSQRAISRNREMLSLSLDTLAYRFQHPLSA 74 M +S + LYQS++Q ++A+ + +N+ ++QR+ISRN E+L+L+LD+L +R++H Sbjct: 1 MTATVSCAVLYQSHRQVERAAIEHGANIARIAQRSISRNVELLTLALDSLTWRYRHT-QL 59 Query: 75 RRLNDAQRYAYLFGSTTNVSHIAVMAVLDADGRVQV-SSRLGRGKGAPHYADRAYFIAHR 133 + Q+ +L G ++A + ++D DG + V S+ L + P YA +F AH+ Sbjct: 60 HEMPLQQKMEFLLGENIEARYVAALGIVDTDGELVVGSAALSQILPGP-YAQSDFFTAHQ 118 Query: 134 D---SPTVGLYVSRPMQASLGNELQVVVLSKRLSNEDGSFAGVVVMALDLAYFRELFEGL 190 GLY+S P+ L +QVVVLSKRL+ DGSFAG+ +M L L YFR+LF+GL Sbjct: 119 THHAQGDTGLYISAPLTVRLERRMQVVVLSKRLAQPDGSFAGISLMVLYLDYFRDLFQGL 178 Query: 191 ALGDEGIISLYSDEGIAYMRVPYRETIIGRDVSQTGNFQRLRAMLSEEEGSFFAHATNDG 250 L ++G+ISLYS +G+AYMR+PY E IG ++ + + +R+ + +GS+FA A DG Sbjct: 179 TLENDGVISLYSADGLAYMRIPYNEAFIGSRLNISEDLERIFSPSGPAQGSYFARAQQDG 238 Query: 251 VRRLYTFRRIPGSPLIVFVGYAEEAIFKTWRKTFYAVLVSLAIFGLLTVWLLLHVRQELR 310 R LYTF R+PG+ VF+G IF+ W YAVL +A F + +++L+ VR EL+ Sbjct: 239 PRWLYTFARVPGTGWTVFIGRTGARIFREWYNMLYAVLFLMASFCIASIYLIRRVRVELQ 298 Query: 311 RRVTAERQLEALARTDGLTGLLNRRALDEALQATWERCQRNLGASFSVLFIDVDYFKAYN 370 RR ++QLE LARTD LT LLNRRALDEAL W+R + N A FS+LF+DVD+FK YN Sbjct: 299 RRSALDQQLEELARTDKLTSLLNRRALDEALARAWKRAEENPDAIFSLLFVDVDFFKLYN 358 Query: 371 DTYGHKLGDTVLKEVAATLTARLPRHTDCAGRYGGEEFVVLLEQTDLQGAQMMAQRLCDA 430 DTYGHK GD L V+ + A + R +D +GRYGGEEFVVLL TD GA +A+R+ A Sbjct: 359 DTYGHKAGDYALMAVSRCIVAAVSRLSDQSGRYGGEEFVVLLNGTDTVGATHVAKRIISA 418 Query: 431 VRERHIAHTSSPLAVVTISVGVATLERDHHRRVEDVLNAADAALYRAKREGRN 483 ++ I H SP ++T+S+GV +L R+HH +EDV+ ADAALYRAK++GRN Sbjct: 419 IQSLKIPHERSPFDILTVSIGVTSLLREHHSSIEDVVKDADAALYRAKQDGRN 471 >B4EA36.1 B4EA36_BURCJ Putative diguanylate cyclase Length = 492 Score = 357 bits (915), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 210/486 (43%), Positives = 275/486 (56%), Gaps = 13/486 (2%) Query: 4 YLVVILAIAV-LMVMAISASTLYQSYQQTRQSAVSNASNVTLVSQRAISRNREMLSLSLD 62 Y VV + I + +M + L+QS + A + N+ L+++R I RN E+ LSL Sbjct: 9 YFVVAVGIVIACALMGLCVLQLFQSRHDALERASETSRNLGLMAERDIERNLELYDLSLQ 68 Query: 63 TLAYRFQHPLSARRLNDAQRYAYLFGSTTNVSHIAVMAVLDADGRVQVSSRLGRGKGAP- 121 L + Q P A R LF I VLDADG + + S P Sbjct: 69 ALIHGLQRP-DVMAAAPALRREALFDHAMTAQFIGSQLVLDADGNIILDS----ANDVPR 123 Query: 122 --HYADRAYFIAHRDSPTVGLYVSRPMQASLGNELQVVVLSKRLSNEDGSFAGVVVMALD 179 ++ADR YF HRD+P VGLYVS P + L + + LS+R+SN DGSFAG+ ++A++ Sbjct: 124 KGNFADRRYFTIHRDNPNVGLYVSDPFVSRLRAGMLSIALSRRISNPDGSFAGIALIAIN 183 Query: 180 LAYFRELFEGLALGDEGIISLYSDEGIAYMRVPYRETIIGRDVSQTGNFQRLRAMLSEEE 239 L YF +LF GL+LG G ISL +GI MR PY IGRD+ + FQR R S E Sbjct: 184 LEYFHKLFAGLSLGQHGSISLIGKDGIMVMRQPYDVRTIGRDIGKAATFQRFR---SAPE 240 Query: 240 GSFFAHATNDGVRRLYTFRRIPGSPLIVFVGYAEEAIFKTWRKTFYAVLVSLAIFGLLTV 299 GSF A+ DGVRRLY F+ +P PLI+ V AE+ I+ WR+ + + +A FG + Sbjct: 241 GSFSETASIDGVRRLYYFKNLPTLPLIIMVAEAEQDIYAAWRRRAETIGLLVATFGAAFI 300 Query: 300 WLLLHVRQELRRRVTAERQLEALARTDGLTGLLNRRALDEALQATWERCQRNLGASFSVL 359 L + + +LRRR+ AE +LE LARTDGLTGL NRR+ E L W R +R + FS+L Sbjct: 301 ALSVFLGVQLRRRMRAESELELLARTDGLTGLNNRRSFGEVLDREWRRARRA-HSVFSLL 359 Query: 360 FIDVDYFKAYNDTYGHKLGDTVLKEVAATLTARLPRHTDCAGRYGGEEFVVLLEQTDLQG 419 F+DVD FKAYNDTYGH+ GD L VA + + R TD A RYGGEEFVVLL T G Sbjct: 360 FVDVDRFKAYNDTYGHQAGDDALAAVARCIGENIRRPTDTAARYGGEEFVVLLPDTPPTG 419 Query: 420 AQMMAQRLCDAVRERHIAHTSSPLAVVTISVGVATLERDHHRRVEDVLNAADAALYRAKR 479 A A+R+ A+ E + H S VT S+G+A+ D V+ AAD ALY AK Sbjct: 420 AAQTAERIRAAINELALEHAGSEYGRVTASIGLASWTPDQDGDPGAVIKAADEALYYAKA 479 Query: 480 EGRNAV 485 GRN V Sbjct: 480 AGRNKV 485 >Q1BH63.1 Q1BH63_BURCA Diguanylate cyclase Length = 492 Score = 348 bits (893), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 208/488 (42%), Positives = 282/488 (57%), Gaps = 21/488 (4%) Query: 7 VILAIAVLM---VMAISASTLYQSYQQTRQSAVSNASNVTLVSQRAISRNREMLSLSLDT 63 VI+AIA ++ +MA+ L QS + A + N+ LV++R I RN E+ LSL Sbjct: 10 VIVAIASMIACALMALCVLQLLQSRDDAMERARETSRNLGLVAERDIERNFELYDLSLQA 69 Query: 64 LAYRFQHPLSARRLNDAQ---RYAYLFGSTTNVSHIAVMAVLDADGRVQVSSRLGRGKGA 120 + H L R + DA R A LF + M V+DA G + + S G Sbjct: 70 VI----HGLQRRDVMDASPSLRRAVLFDHAMTAEFLGSMLVMDAGGNIVLDS----GYDE 121 Query: 121 P---HYADRAYFIAHRDSPTVGLYVSRPMQASLGNELQVVVLSKRLSNEDGSFAGVVVMA 177 P ++ADR YF HRD+P VGLYVS P + L + + L++R+SN DGSF G+ V+A Sbjct: 122 PRKGNFADRRYFTIHRDNPNVGLYVSDPFVSRLRGGMLSIALTRRISNPDGSFGGIAVIA 181 Query: 178 LDLAYFRELFEGLALGDEGIISLYSDEGIAYMRVPYRETIIGRDVSQTGNFQRLRAMLSE 237 ++L YF +LF GL+LG G ISL ++G MR PY IGRD+S+ F+R + + Sbjct: 182 VNLEYFHQLFAGLSLGKHGSISLIGEDGKMVMRQPYDVHTIGRDLSKAATFRRFQ---TA 238 Query: 238 EEGSFFAHATNDGVRRLYTFRRIPGSPLIVFVGYAEEAIFKTWRKTFYAVLVSLAIFGLL 297 EGSF ++ DGVRRLY F+ +P PLI+ V AE+ I+ WR+ + +A FG+ Sbjct: 239 REGSFSETSSIDGVRRLYYFKHLPKLPLIIMVAEAEQDIYAAWRQRAITIGGLVATFGVA 298 Query: 298 TVWLLLHVRQELRRRVTAERQLEALARTDGLTGLLNRRALDEALQATWERCQRNLGASFS 357 + L L + +LRRR+ AE +L LARTDGLTGL NRR+ E L W R +R + FS Sbjct: 299 FIALSLLLGSQLRRRMRAESELVLLARTDGLTGLSNRRSFGEVLDNEWRRARRAR-SVFS 357 Query: 358 VLFIDVDYFKAYNDTYGHKLGDTVLKEVAATLTARLPRHTDCAGRYGGEEFVVLLEQTDL 417 +LF+DVD FKAYNDTYGH+ GD L VA + + R D A RYGGEEFVVLL T Sbjct: 358 LLFVDVDRFKAYNDTYGHQAGDDALAAVARCIGENIRRPADTAARYGGEEFVVLLPDTSQ 417 Query: 418 QGAQMMAQRLCDAVRERHIAHTSSPLAVVTISVGVATLERDHHRRVEDVLNAADAALYRA 477 GA +A+R+ A+ E + H S VT S+G+A+ D + + V+ AAD ALY A Sbjct: 418 TGAAQIAERIRAAIDELALEHAGSEYGRVTASIGLASWTPDQEGQPDAVIKAADEALYYA 477 Query: 478 KREGRNAV 485 K GRN V Sbjct: 478 KATGRNKV 485 >A0K825.1 A0K825_BURCH Diguanylate cyclase Length = 492 Score = 348 bits (893), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 208/488 (42%), Positives = 282/488 (57%), Gaps = 21/488 (4%) Query: 7 VILAIAVLM---VMAISASTLYQSYQQTRQSAVSNASNVTLVSQRAISRNREMLSLSLDT 63 VI+AIA ++ +MA+ L QS + A + N+ LV++R I RN E+ LSL Sbjct: 10 VIVAIASMIACALMALCVLQLLQSRDDAMERARETSRNLGLVAERDIERNFELYDLSLQA 69 Query: 64 LAYRFQHPLSARRLNDAQ---RYAYLFGSTTNVSHIAVMAVLDADGRVQVSSRLGRGKGA 120 + H L R + DA R A LF + M V+DA G + + S G Sbjct: 70 VI----HGLQRRDVMDASPSLRRAVLFDHAMTAEFLGSMLVMDAGGNIVLDS----GYDE 121 Query: 121 P---HYADRAYFIAHRDSPTVGLYVSRPMQASLGNELQVVVLSKRLSNEDGSFAGVVVMA 177 P ++ADR YF HRD+P VGLYVS P + L + + L++R+SN DGSF G+ V+A Sbjct: 122 PRKGNFADRRYFTIHRDNPNVGLYVSDPFVSRLRGGMLSIALTRRISNPDGSFGGIAVIA 181 Query: 178 LDLAYFRELFEGLALGDEGIISLYSDEGIAYMRVPYRETIIGRDVSQTGNFQRLRAMLSE 237 ++L YF +LF GL+LG G ISL ++G MR PY IGRD+S+ F+R + + Sbjct: 182 VNLEYFHQLFAGLSLGKHGSISLIGEDGKMVMRQPYDVHTIGRDLSKAATFRRFQ---TA 238 Query: 238 EEGSFFAHATNDGVRRLYTFRRIPGSPLIVFVGYAEEAIFKTWRKTFYAVLVSLAIFGLL 297 EGSF ++ DGVRRLY F+ +P PLI+ V AE+ I+ WR+ + +A FG+ Sbjct: 239 REGSFSETSSIDGVRRLYYFKHLPKLPLIIMVAEAEQDIYAAWRQRAITIGGLVATFGVA 298 Query: 298 TVWLLLHVRQELRRRVTAERQLEALARTDGLTGLLNRRALDEALQATWERCQRNLGASFS 357 + L L + +LRRR+ AE +L LARTDGLTGL NRR+ E L W R +R + FS Sbjct: 299 FIALSLLLGSQLRRRMRAESELVLLARTDGLTGLSNRRSFGEVLDNEWRRARRAR-SVFS 357 Query: 358 VLFIDVDYFKAYNDTYGHKLGDTVLKEVAATLTARLPRHTDCAGRYGGEEFVVLLEQTDL 417 +LF+DVD FKAYNDTYGH+ GD L VA + + R D A RYGGEEFVVLL T Sbjct: 358 LLFVDVDRFKAYNDTYGHQAGDDALAAVARCIGENIRRPADTAARYGGEEFVVLLPDTSQ 417 Query: 418 QGAQMMAQRLCDAVRERHIAHTSSPLAVVTISVGVATLERDHHRRVEDVLNAADAALYRA 477 GA +A+R+ A+ E + H S VT S+G+A+ D + + V+ AAD ALY A Sbjct: 418 TGAAQIAERIRAAIDELALEHAGSEYGRVTASIGLASWTPDQEGQPDAVIKAADEALYYA 477 Query: 478 KREGRNAV 485 K GRN V Sbjct: 478 KATGRNKV 485 >A2VXN5.1 A2VXN5_9BURK Diguanylate cyclase (GGDEF domain) Length = 496 Score = 346 bits (888), Expect = 4e-93, Method: Compositional matrix adjust. Identities = 209/493 (42%), Positives = 282/493 (57%), Gaps = 21/493 (4%) Query: 2 KNYLVVILAIAVLM---VMAISASTLYQSYQQTRQSAVSNASNVTLVSQRAISRNREMLS 58 K VI+AIA L+ +MA+ L QS + A + N+ LV++R I RN E+ Sbjct: 9 KTAPYVIVAIASLIACALMALCVLQLLQSRNDAMERARETSRNLGLVAERDIERNIELYD 68 Query: 59 LSLDTLAYRFQHPLSARRLNDAQ---RYAYLFGSTTNVSHIAVMAVLDADGRVQVSSRLG 115 LSL + H L R + DA R A LF + M V+DA G + + S Sbjct: 69 LSLQAVI----HGLQRRDVMDASPGLRRAVLFDHAMTAEFLGSMLVMDAGGNIVLDS--- 121 Query: 116 RGKGAP---HYADRAYFIAHRDSPTVGLYVSRPMQASLGNELQVVVLSKRLSNEDGSFAG 172 G P ++ADR YF HRD+P VGLY+S P + L + L++R+SN DGSF G Sbjct: 122 -GYDEPRKGNFADRRYFTIHRDNPNVGLYISDPFVSRLRGGKLSIALTRRISNPDGSFGG 180 Query: 173 VVVMALDLAYFRELFEGLALGDEGIISLYSDEGIAYMRVPYRETIIGRDVSQTGNFQRLR 232 + V+A++L YF +LF GL+LG G ISL ++G MR PY IGRD+S+ F+R + Sbjct: 181 IAVIAVNLEYFHQLFAGLSLGKHGSISLIGEDGKMVMRQPYDVHTIGRDLSKAATFRRFQ 240 Query: 233 AMLSEEEGSFFAHATNDGVRRLYTFRRIPGSPLIVFVGYAEEAIFKTWRKTFYAVLVSLA 292 + EGSF ++ DGVRRLY F+ +P PLI+ V AE+ I+ WR+ + +A Sbjct: 241 ---TAREGSFSETSSIDGVRRLYYFKHLPKLPLIIMVAEAEQDIYAAWRQRAITIGGLVA 297 Query: 293 IFGLLTVWLLLHVRQELRRRVTAERQLEALARTDGLTGLLNRRALDEALQATWERCQRNL 352 FG+ + L L + +LRRR+ AE +L LARTDGLTGL NRR+ E L W R +R Sbjct: 298 TFGVAFIALSLLLGAQLRRRMRAESELVLLARTDGLTGLSNRRSFGEVLDNEWRRARRAR 357 Query: 353 GASFSVLFIDVDYFKAYNDTYGHKLGDTVLKEVAATLTARLPRHTDCAGRYGGEEFVVLL 412 + FS+LF+DVD FKAYNDTYGH+ GD L VA + + R D A RYGGEEFVVLL Sbjct: 358 -SVFSLLFVDVDRFKAYNDTYGHQAGDDALAAVARCIGENIRRPADTAARYGGEEFVVLL 416 Query: 413 EQTDLQGAQMMAQRLCDAVRERHIAHTSSPLAVVTISVGVATLERDHHRRVEDVLNAADA 472 T GA +A+R+ A+ E + H S VT S+G+A+ D + + V+ AAD Sbjct: 417 PDTPQTGAAQIAERIRAAIDELALEHAGSEYGRVTASIGLASWTPDQEGQPDAVIKAADE 476 Query: 473 ALYRAKREGRNAV 485 ALY AK GRN V Sbjct: 477 ALYYAKATGRNKV 489 >A4JS67.1 A4JS67_BURVG Diguanylate cyclase Length = 507 Score = 345 bits (886), Expect = 7e-93, Method: Compositional matrix adjust. Identities = 202/486 (41%), Positives = 276/486 (56%), Gaps = 13/486 (2%) Query: 4 YLVVILAIAV-LMVMAISASTLYQSYQQTRQSAVSNASNVTLVSQRAISRNREMLSLSLD 62 YL+V + + + +M + L+QS + A +A N+ L+++R I RN E+ LSL Sbjct: 9 YLIVAIGVVIACALMGLCVLQLFQSRHDALERASESARNLGLMAERDIERNFELYDLSLQ 68 Query: 63 TLAYRFQHPLSARRLNDAQRYAYLFGSTTNVSHIAVMAVLDADGRVQVSSRLGRGKGAP- 121 LA+ Q P A R A LF + + I VLD DG + + S P Sbjct: 69 ALAHGLQRP-DVMAAAPALRRAVLFDHAMSAAFIGSQLVLDTDGNIVLDS----AHDVPR 123 Query: 122 --HYADRAYFIAHRDSPTVGLYVSRPMQASLGNELQVVVLSKRLSNEDGSFAGVVVMALD 179 ++AD YF HRD+ VGLY+S P + L + LS+R+SN DGSFAG+ ++ L+ Sbjct: 124 QGNFADHKYFTVHRDNADVGLYISDPFISRLSAGTPSMALSRRISNPDGSFAGIALIGLN 183 Query: 180 LAYFRELFEGLALGDEGIISLYSDEGIAYMRVPYRETIIGRDVSQTGNFQRLRAMLSEEE 239 L YF LF GL+LG G ISL +GI MR P+ + I+GRD+SQ F+R +S E Sbjct: 184 LEYFHHLFAGLSLGQHGSISLIGTDGIMVMRQPFTDGIVGRDISQASTFRRF---MSARE 240 Query: 240 GSFFAHATNDGVRRLYTFRRIPGSPLIVFVGYAEEAIFKTWRKTFYAVLVSLAIFGLLTV 299 G F A+ DGVRRLY F+ +P PLI+ V AE+ I+ W + A+ + FG + Sbjct: 241 GVFSETASIDGVRRLYYFKHLPELPLIIMVAEAEQDIYAAWWQRAVAIGALVGTFGAAFI 300 Query: 300 WLLLHVRQELRRRVTAERQLEALARTDGLTGLLNRRALDEALQATWERCQRNLGASFSVL 359 L + + ++LRRR+ AE +L LARTDGLTGL NRR+ E L+ W R QR + FS+L Sbjct: 301 VLSMVLSKQLRRRMRAESELVLLARTDGLTGLNNRRSFGEVLEREWRRAQRA-HSVFSLL 359 Query: 360 FIDVDYFKAYNDTYGHKLGDTVLKEVAATLTARLPRHTDCAGRYGGEEFVVLLEQTDLQG 419 F+DVD FKAYNDTYGH+ GD L VA + + R D A RYGGEEFVVLL T QG Sbjct: 360 FVDVDRFKAYNDTYGHQAGDDALAAVARCIGENIRRPADTAARYGGEEFVVLLPDTPRQG 419 Query: 420 AQMMAQRLCDAVRERHIAHTSSPLAVVTISVGVATLERDHHRRVEDVLNAADAALYRAKR 479 A +A+R+ A+ + + H S VT S+G+A+ ++ AAD ALY AK Sbjct: 420 AIEIAERIRGAIHDLALEHVGSEYGRVTASIGMASSTPGQDGDPGALIKAADEALYYAKA 479 Query: 480 EGRNAV 485 GRN V Sbjct: 480 TGRNKV 485 >B1YVN5.1 B1YVN5_BURA4 Diguanylate cyclase Length = 492 Score = 345 bits (885), Expect = 9e-93, Method: Compositional matrix adjust. Identities = 201/488 (41%), Positives = 277/488 (56%), Gaps = 17/488 (3%) Query: 4 YLVVILAIAV-LMVMAISASTLYQSYQQTRQSAVSNASNVTLVSQRAISRNREMLSLSLD 62 Y++V + I + +M + L+QS + A + N+ L+++R I RN E+ LSL Sbjct: 9 YVIVAVGIVIACALMGLCVLQLFQSRNDALERASETSRNLGLIAERDIERNFELYDLSLQ 68 Query: 63 TLAYRFQHP--LSARRLNDAQRYAYLFGSTTNVSHIAVMAVLDADGRVQVSSRLGRGKGA 120 + Q P +SA A R LF + I VLDA+G + + S Sbjct: 69 AVIQGLQRPDVMSA---APALRRGVLFDHAMSAPFIGSQLVLDANGDIVLDS----ANDV 121 Query: 121 P---HYADRAYFIAHRDSPTVGLYVSRPMQASLGNELQVVVLSKRLSNEDGSFAGVVVMA 177 P ++ADR YF HRD+P VGLYVS P + L + +VLS+R+SN DGSF GV ++A Sbjct: 122 PRKGNFADRKYFTVHRDNPDVGLYVSDPFVSRLRAGMLCIVLSRRISNPDGSFGGVALIA 181 Query: 178 LDLAYFRELFEGLALGDEGIISLYSDEGIAYMRVPYRETIIGRDVSQTGNFQRLRAMLSE 237 ++L YF +LF GL+LG G +SL +GI MR PY +I+GRD+S+ F+R + Sbjct: 182 INLEYFHQLFAGLSLGQHGSMSLIGKDGIMVMRQPYNVSIVGRDISKAATFRRFQ---RA 238 Query: 238 EEGSFFAHATNDGVRRLYTFRRIPGSPLIVFVGYAEEAIFKTWRKTFYAVLVSLAIFGLL 297 EG F A+ DGVRRLY F+ +P PLI+ V E+ ++ WR + +A FG+ Sbjct: 239 SEGVFSETASIDGVRRLYYFKHLPKLPLIIMVAEGEQDVYAAWRHRAVTIGALVATFGVA 298 Query: 298 TVWLLLHVRQELRRRVTAERQLEALARTDGLTGLLNRRALDEALQATWERCQRNLGASFS 357 + L + +LRRR+ AE +L LARTDGLTGL NRR+ E L W R +R + FS Sbjct: 299 FIALSFLLSGQLRRRMRAESELVLLARTDGLTGLNNRRSFGEVLDREWRRARRT-HSVFS 357 Query: 358 VLFIDVDYFKAYNDTYGHKLGDTVLKEVAATLTARLPRHTDCAGRYGGEEFVVLLEQTDL 417 +LF+DVD FKAYNDTYGH+ GD L VA + + R D A RYGGEEFVVLL T Sbjct: 358 LLFVDVDRFKAYNDTYGHQAGDDALAAVARCIGENIRRPVDTAARYGGEEFVVLLPDTPP 417 Query: 418 QGAQMMAQRLCDAVRERHIAHTSSPLAVVTISVGVATLERDHHRRVEDVLNAADAALYRA 477 GA +A+R+ A+ E + H S VT S+G+A+ + + V+ AAD ALY A Sbjct: 418 AGAAQIAERIRAAIDELALEHAGSEYGRVTASIGLASWTPEQDNEPDAVIKAADEALYYA 477 Query: 478 KREGRNAV 485 K GRN V Sbjct: 478 KTIGRNRV 485 >A4JS04.1 A4JS04_BURVG Diguanylate cyclase Length = 516 Score = 345 bits (884), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 201/483 (41%), Positives = 276/483 (57%), Gaps = 7/483 (1%) Query: 4 YLVVILAIAV-LMVMAISASTLYQSYQQTRQSAVSNASNVTLVSQRAISRNREMLSLSLD 62 YL+V + + + +M + L+QS + A +A N+ L+++R I RN E+ LSL Sbjct: 9 YLIVAIGVVIACALMGLCVLQLFQSRHDALERASESARNLGLMAERDIERNFELYDLSLQ 68 Query: 63 TLAYRFQHPLSARRLNDAQRYAYLFGSTTNVSHIAVMAVLDADGRVQVSSRLGRGKGAPH 122 LA+ Q P A R A LF + + I VLD DG + + S + + Sbjct: 69 ALAHGLQRP-DVMAAAPALRRAVLFDHAMSAAFIGSQLVLDTDGNIVLDSAHDVPRQG-N 126 Query: 123 YADRAYFIAHRDSPTVGLYVSRPMQASLGNELQVVVLSKRLSNEDGSFAGVVVMALDLAY 182 +AD YF HRD+ VGLY+S P + L + LS+R+SN DGSFAG+ ++ L+L Y Sbjct: 127 FADHKYFTVHRDNADVGLYISDPFISRLSAGTPSMALSRRISNPDGSFAGIALIGLNLEY 186 Query: 183 FRELFEGLALGDEGIISLYSDEGIAYMRVPYRETIIGRDVSQTGNFQRLRAMLSEEEGSF 242 F LF GL+LG G ISL +GI MR P+ + I+GRD+SQ F+R +S EG F Sbjct: 187 FHHLFAGLSLGQHGSISLIGTDGIMVMRQPFTDGIVGRDISQASTFRRF---MSAREGVF 243 Query: 243 FAHATNDGVRRLYTFRRIPGSPLIVFVGYAEEAIFKTWRKTFYAVLVSLAIFGLLTVWLL 302 A+ DGVRRLY F+ +P PLI+ V AE+ I+ W + A+ + FG + L Sbjct: 244 SETASIDGVRRLYYFKHLPELPLIIMVAEAEQDIYAAWWQRAVAIGALVGTFGAAFIVLS 303 Query: 303 LHVRQELRRRVTAERQLEALARTDGLTGLLNRRALDEALQATWERCQRNLGASFSVLFID 362 + + ++LRRR+ AE +L LARTDGLTGL NRR+ E L+ W R QR + FS+LF+D Sbjct: 304 MVLSKQLRRRMRAESELVLLARTDGLTGLNNRRSFGEVLEREWRRAQRA-HSVFSLLFVD 362 Query: 363 VDYFKAYNDTYGHKLGDTVLKEVAATLTARLPRHTDCAGRYGGEEFVVLLEQTDLQGAQM 422 VD FKAYNDTYGH+ GD L VA + + R D A RYGGEEFVVLL T QGA Sbjct: 363 VDRFKAYNDTYGHQAGDDALAAVARCIGENIRRPADTAARYGGEEFVVLLPDTPRQGAIE 422 Query: 423 MAQRLCDAVRERHIAHTSSPLAVVTISVGVATLERDHHRRVEDVLNAADAALYRAKREGR 482 +A+R+ A+ + + H S VT S+G+A+ ++ AAD ALY AK GR Sbjct: 423 IAERIRGAIDDLALEHVGSEYGRVTASIGMASSTPGQDGDPGALIKAADEALYYAKATGR 482 Query: 483 NAV 485 N V Sbjct: 483 NKV 485