BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0339.p (270 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IXX5.1 D8IXX5_HERSS Short-chain dehydrogenase protein 536 e-150 B4EIY8.1 B4EIY8_BURCJ Putative short chain dehydrogenase 413 e-113 Q1LEN8.1 Q1LEN8_RALME Short-chain dehydrogenase/reductase SDR EC... 411 e-113 Q395P1.1 Q395P1_BURS3 Short-chain dehydrogenase/reductase SDR EC... 411 e-113 Q1BN55.1 Q1BN55_BURCA Short-chain dehydrogenase/reductase SDR 410 e-112 A0B063.1 A0B063_BURCH Short-chain dehydrogenase/reductase SDR 410 e-112 E1TIG2.1 E1TIG2_BURSG Short-chain dehydrogenase/reductase SDR 409 e-112 B1K888.1 B1K888_BURCC Short-chain dehydrogenase/reductase SDR 409 e-112 A9AKK8.1 A9AKK8_BURM1 Short-chain dehydrogenase/reductase SDR 408 e-112 B1TF94.1 B1TF94_9BURK Short-chain dehydrogenase/reductase SDR 408 e-112 >D8IXX5.1 D8IXX5_HERSS Short-chain dehydrogenase protein Length = 270 Score = 536 bits (1381), Expect = e-150, Method: Compositional matrix adjust. Identities = 268/270 (99%), Positives = 269/270 (99%) Query: 1 MNQPHTPAHRGTALVTGASSGIGAIYADRLARLGYDLILVARNRSRLNTLAERITNQTGR 60 MNQPHTPAHRGTALVTGASSGIGAIYADRLARLGYDLILVARNRSRLNTLAERITNQTGR Sbjct: 1 MNQPHTPAHRGTALVTGASSGIGAIYADRLARLGYDLILVARNRSRLNTLAERITNQTGR 60 Query: 61 SVEVLEADLGQAASLAQVEEKLRSDASITLLVNNAGIGTHTPLLQSDVDHMTGMIALNVT 120 SVEVLEADLGQAASLAQVEEKLRSDASITLLVNNAGIGTHTPLLQSDV+HMTGMIALNVT Sbjct: 61 SVEVLEADLGQAASLAQVEEKLRSDASITLLVNNAGIGTHTPLLQSDVEHMTGMIALNVT 120 Query: 121 APTRLTYAAVPGFVARGQGAVINISSIVGVAPEVLNGVYGGSKAFVLAFSQSLHHELAAQ 180 APTRLTYAAVPGFVARGQGAVINISSIVGVAPEVLNGVYGGSKAFVLAFSQSLHHELAAQ Sbjct: 121 APTRLTYAAVPGFVARGQGAVINISSIVGVAPEVLNGVYGGSKAFVLAFSQSLHHELAAQ 180 Query: 181 GVQVQAVLPGATATDFWAIGGLPVEHLDPAIVMSAEQMVDAALVGFQRGELVTIPSLHEE 240 GVQVQAVLPGATATDFWAIGGLPVEHLDPAIVMSAEQMVDAALVGFQR ELVTIPSLHEE Sbjct: 181 GVQVQAVLPGATATDFWAIGGLPVEHLDPAIVMSAEQMVDAALVGFQRRELVTIPSLHEE 240 Query: 241 DAWTGYEAARQALIARLSANTPAPRYRAAH 270 DAWTGYEAARQALIARLSANTPAPRYRAAH Sbjct: 241 DAWTGYEAARQALIARLSANTPAPRYRAAH 270 >B4EIY8.1 B4EIY8_BURCJ Putative short chain dehydrogenase Length = 281 Score = 413 bits (1061), Expect = e-113, Method: Compositional matrix adjust. Identities = 207/264 (78%), Positives = 227/264 (85%) Query: 6 TPAHRGTALVTGASSGIGAIYADRLARLGYDLILVARNRSRLNTLAERITNQTGRSVEVL 65 T AHRGTAL+TGASSGIGA+YADRLAR GYDLILVAR+R RL+ LAERITN T RSVE++ Sbjct: 17 TQAHRGTALITGASSGIGAVYADRLARRGYDLILVARSRERLSALAERITNDTQRSVEIV 76 Query: 66 EADLGQAASLAQVEEKLRSDASITLLVNNAGIGTHTPLLQSDVDHMTGMIALNVTAPTRL 125 +ADL A+LA VE KL+ DASITLLVNNAGIGTH PLL SDVD MT MI LNVTA TRL Sbjct: 77 DADLNDRAALAAVEAKLKQDASITLLVNNAGIGTHAPLLDSDVDAMTRMIDLNVTALTRL 136 Query: 126 TYAAVPGFVARGQGAVINISSIVGVAPEVLNGVYGGSKAFVLAFSQSLHHELAAQGVQVQ 185 TYAAVPGFVARG+GAVINISSIV ++PE LNGVYGGSKAFVLAFSQSLHHELA +GVQVQ Sbjct: 137 TYAAVPGFVARGRGAVINISSIVAISPETLNGVYGGSKAFVLAFSQSLHHELAGKGVQVQ 196 Query: 186 AVLPGATATDFWAIGGLPVEHLDPAIVMSAEQMVDAALVGFQRGELVTIPSLHEEDAWTG 245 AVLPGATATDFW GGLP+EHL IVM+A+ MVDAALVGF+RGELVTIPSLH D W Sbjct: 197 AVLPGATATDFWQTGGLPLEHLPKEIVMTAQDMVDAALVGFERGELVTIPSLHAGDEWDA 256 Query: 246 YEAARQALIARLSANTPAPRYRAA 269 YEAAR+ + LSA+TPAPRY AA Sbjct: 257 YEAARRTMAPHLSADTPAPRYTAA 280 >Q1LEN8.1 Q1LEN8_RALME Short-chain dehydrogenase/reductase SDR EC=1.1.1.62 Length = 266 Score = 411 bits (1057), Expect = e-113, Method: Compositional matrix adjust. Identities = 207/261 (79%), Positives = 222/261 (85%) Query: 6 TPAHRGTALVTGASSGIGAIYADRLARLGYDLILVARNRSRLNTLAERITNQTGRSVEVL 65 T H GTALVTGASSGIGAIYADRLAR GYDLILVARNR +L+TLA RIT+ T R VEV Sbjct: 2 TQTHLGTALVTGASSGIGAIYADRLARRGYDLILVARNRDKLDTLARRITDDTQRVVEVF 61 Query: 66 EADLGQAASLAQVEEKLRSDASITLLVNNAGIGTHTPLLQSDVDHMTGMIALNVTAPTRL 125 ADL SLA+VEEKLR DASITLLVNNAG+GTHTPLL SDVD M MI LNVTA TRL Sbjct: 62 PADLNDRQSLARVEEKLRQDASITLLVNNAGVGTHTPLLDSDVDAMNRMIDLNVTALTRL 121 Query: 126 TYAAVPGFVARGQGAVINISSIVGVAPEVLNGVYGGSKAFVLAFSQSLHHELAAQGVQVQ 185 TYAAVPGFVARG+GA+INISSIVG+APE+LNGVYGGSKAFVLAFSQSLHHELAA+G++VQ Sbjct: 122 TYAAVPGFVARGRGAIINISSIVGIAPEILNGVYGGSKAFVLAFSQSLHHELAAKGLRVQ 181 Query: 186 AVLPGATATDFWAIGGLPVEHLDPAIVMSAEQMVDAALVGFQRGELVTIPSLHEEDAWTG 245 AVLPGATATDFW GGLP+EHLD AIVM AE MVDAALVGF RGELVTIP LH + W Sbjct: 182 AVLPGATATDFWETGGLPIEHLDKAIVMPAEAMVDAALVGFDRGELVTIPPLHAIEQWNA 241 Query: 246 YEAARQALIARLSANTPAPRY 266 YE ARQA+ LS NTPAPRY Sbjct: 242 YEGARQAMAGLLSTNTPAPRY 262 >Q395P1.1 Q395P1_BURS3 Short-chain dehydrogenase/reductase SDR EC=1.1.1.62 Length = 266 Score = 411 bits (1057), Expect = e-113, Method: Compositional matrix adjust. Identities = 208/264 (78%), Positives = 224/264 (84%) Query: 6 TPAHRGTALVTGASSGIGAIYADRLARLGYDLILVARNRSRLNTLAERITNQTGRSVEVL 65 T AHRGTAL+TGASSGIGA+YADRLAR GYDLILVARNR RL LAERITN+T RSVE++ Sbjct: 2 TQAHRGTALITGASSGIGAVYADRLARRGYDLILVARNRDRLVALAERITNETRRSVEII 61 Query: 66 EADLGQAASLAQVEEKLRSDASITLLVNNAGIGTHTPLLQSDVDHMTGMIALNVTAPTRL 125 ADL A+LA VE KL+ DASITLLVNNAGIGTH PLL SDVD MT MI LNVTA TRL Sbjct: 62 GADLNDRAALATVEAKLKQDASITLLVNNAGIGTHAPLLDSDVDAMTRMIDLNVTALTRL 121 Query: 126 TYAAVPGFVARGQGAVINISSIVGVAPEVLNGVYGGSKAFVLAFSQSLHHELAAQGVQVQ 185 TYAAVPGFVARG+G+VINISSIV ++PE LNGVYGGSKAFVLAFSQSLHHELA +GVQVQ Sbjct: 122 TYAAVPGFVARGRGSVINISSIVAISPETLNGVYGGSKAFVLAFSQSLHHELAGKGVQVQ 181 Query: 186 AVLPGATATDFWAIGGLPVEHLDPAIVMSAEQMVDAALVGFQRGELVTIPSLHEEDAWTG 245 AVLPGATATDFW GGLP+EHL IVMSA MVDAALVGF RGELVTIPSLH D WT Sbjct: 182 AVLPGATATDFWQTGGLPLEHLPKEIVMSANDMVDAALVGFDRGELVTIPSLHAGDEWTA 241 Query: 246 YEAARQALIARLSANTPAPRYRAA 269 YEAAR+ + LSA+TPAPRY A Sbjct: 242 YEAARRTMAPHLSADTPAPRYATA 265 >Q1BN55.1 Q1BN55_BURCA Short-chain dehydrogenase/reductase SDR Length = 281 Score = 410 bits (1054), Expect = e-112, Method: Compositional matrix adjust. Identities = 206/264 (78%), Positives = 225/264 (85%) Query: 6 TPAHRGTALVTGASSGIGAIYADRLARLGYDLILVARNRSRLNTLAERITNQTGRSVEVL 65 T AHRGTAL+TGASSGIGA+YADRLAR GYDLILVARNR RL+ LAERITN T RSVE++ Sbjct: 17 TQAHRGTALITGASSGIGAVYADRLARRGYDLILVARNRDRLSALAERITNDTQRSVEIV 76 Query: 66 EADLGQAASLAQVEEKLRSDASITLLVNNAGIGTHTPLLQSDVDHMTGMIALNVTAPTRL 125 +ADL A+LA VE KL+ DASITLLVNNAGIGTH PLL SDVD MT MI LNVTA TRL Sbjct: 77 DADLNDRAALAAVEAKLKQDASITLLVNNAGIGTHAPLLDSDVDAMTRMIELNVTALTRL 136 Query: 126 TYAAVPGFVARGQGAVINISSIVGVAPEVLNGVYGGSKAFVLAFSQSLHHELAAQGVQVQ 185 TYAAVPGFVARG+GAVINI+SIV ++PE LNGVYGGSKAFVLAFSQSLHHELA +GVQVQ Sbjct: 137 TYAAVPGFVARGRGAVINIASIVAISPETLNGVYGGSKAFVLAFSQSLHHELADKGVQVQ 196 Query: 186 AVLPGATATDFWAIGGLPVEHLDPAIVMSAEQMVDAALVGFQRGELVTIPSLHEEDAWTG 245 AVLPGATAT+FW GGLP+EHL IVM+A MVDAALVGF+RGELVTIPSLH D W Sbjct: 197 AVLPGATATEFWQTGGLPLEHLPKEIVMTAPDMVDAALVGFERGELVTIPSLHAGDEWEA 256 Query: 246 YEAARQALIARLSANTPAPRYRAA 269 YEAAR+ + LSANTPAPRY A Sbjct: 257 YEAARRTMAPHLSANTPAPRYTTA 280 >A0B063.1 A0B063_BURCH Short-chain dehydrogenase/reductase SDR Length = 281 Score = 410 bits (1054), Expect = e-112, Method: Compositional matrix adjust. Identities = 206/264 (78%), Positives = 225/264 (85%) Query: 6 TPAHRGTALVTGASSGIGAIYADRLARLGYDLILVARNRSRLNTLAERITNQTGRSVEVL 65 T AHRGTAL+TGASSGIGA+YADRLAR GYDLILVARNR RL+ LAERITN T RSVE++ Sbjct: 17 TQAHRGTALITGASSGIGAVYADRLARRGYDLILVARNRDRLSALAERITNDTQRSVEIV 76 Query: 66 EADLGQAASLAQVEEKLRSDASITLLVNNAGIGTHTPLLQSDVDHMTGMIALNVTAPTRL 125 +ADL A+LA VE KL+ DASITLLVNNAGIGTH PLL SDVD MT MI LNVTA TRL Sbjct: 77 DADLNDRAALAAVEAKLKQDASITLLVNNAGIGTHAPLLDSDVDAMTRMIELNVTALTRL 136 Query: 126 TYAAVPGFVARGQGAVINISSIVGVAPEVLNGVYGGSKAFVLAFSQSLHHELAAQGVQVQ 185 TYAAVPGFVARG+GAVINI+SIV ++PE LNGVYGGSKAFVLAFSQSLHHELA +GVQVQ Sbjct: 137 TYAAVPGFVARGRGAVINIASIVAISPETLNGVYGGSKAFVLAFSQSLHHELADKGVQVQ 196 Query: 186 AVLPGATATDFWAIGGLPVEHLDPAIVMSAEQMVDAALVGFQRGELVTIPSLHEEDAWTG 245 AVLPGATAT+FW GGLP+EHL IVM+A MVDAALVGF+RGELVTIPSLH D W Sbjct: 197 AVLPGATATEFWQTGGLPLEHLPKEIVMTAPDMVDAALVGFERGELVTIPSLHAGDEWEA 256 Query: 246 YEAARQALIARLSANTPAPRYRAA 269 YEAAR+ + LSANTPAPRY A Sbjct: 257 YEAARRTMAPHLSANTPAPRYTTA 280 >E1TIG2.1 E1TIG2_BURSG Short-chain dehydrogenase/reductase SDR Length = 265 Score = 409 bits (1051), Expect = e-112, Method: Compositional matrix adjust. Identities = 201/264 (76%), Positives = 228/264 (86%) Query: 6 TPAHRGTALVTGASSGIGAIYADRLARLGYDLILVARNRSRLNTLAERITNQTGRSVEVL 65 T AH+GTAL+TGASSGIGAIYADRLA+ GYDLILVARNR RL L+ RIT+ T RSVE+L Sbjct: 2 TEAHKGTALITGASSGIGAIYADRLAKQGYDLILVARNRERLAALSSRITSATRRSVEIL 61 Query: 66 EADLGQAASLAQVEEKLRSDASITLLVNNAGIGTHTPLLQSDVDHMTGMIALNVTAPTRL 125 +ADL A LA VE KL+ DASITLLVNNAG+GTHTPLL SDVD M MI LNV+A TRL Sbjct: 62 DADLNDKAGLAAVEAKLKQDASITLLVNNAGVGTHTPLLGSDVDAMQRMIDLNVSALTRL 121 Query: 126 TYAAVPGFVARGQGAVINISSIVGVAPEVLNGVYGGSKAFVLAFSQSLHHELAAQGVQVQ 185 TYAAVPGFVARG+GA+INI+SIV +APE+LNGVYGGSKAFVLAFSQSLHHELA +G+QVQ Sbjct: 122 TYAAVPGFVARGKGALINIASIVAIAPEILNGVYGGSKAFVLAFSQSLHHELADKGIQVQ 181 Query: 186 AVLPGATATDFWAIGGLPVEHLDPAIVMSAEQMVDAALVGFQRGELVTIPSLHEEDAWTG 245 AVLPGATAT+FW GGLP+E+LD +IVMSA+ MVDAALVGF+RGEL+TIPSLH + W Sbjct: 182 AVLPGATATEFWQTGGLPLENLDKSIVMSADDMVDAALVGFERGELITIPSLHAVEKWND 241 Query: 246 YEAARQALIARLSANTPAPRYRAA 269 YEAAR+A+ LS NTPAPRYRAA Sbjct: 242 YEAARRAMSTLLSTNTPAPRYRAA 265 >B1K888.1 B1K888_BURCC Short-chain dehydrogenase/reductase SDR Length = 266 Score = 409 bits (1050), Expect = e-112, Method: Compositional matrix adjust. Identities = 206/264 (78%), Positives = 224/264 (84%) Query: 6 TPAHRGTALVTGASSGIGAIYADRLARLGYDLILVARNRSRLNTLAERITNQTGRSVEVL 65 T AHRGTAL+TGASSGIGA+YADRLAR GYDLILVARNR RL+ LAERITN T RSVE++ Sbjct: 2 TQAHRGTALITGASSGIGAVYADRLARRGYDLILVARNRDRLSALAERITNDTQRSVEIV 61 Query: 66 EADLGQAASLAQVEEKLRSDASITLLVNNAGIGTHTPLLQSDVDHMTGMIALNVTAPTRL 125 +ADL A+LA VE KL+ DASITLLVNNAGIGTH PLL SDVD MT MI LNVTA TRL Sbjct: 62 DADLNDRAALAGVEAKLKQDASITLLVNNAGIGTHAPLLDSDVDAMTRMIDLNVTALTRL 121 Query: 126 TYAAVPGFVARGQGAVINISSIVGVAPEVLNGVYGGSKAFVLAFSQSLHHELAAQGVQVQ 185 TYAAVPGFVARG GAVINI+SIV ++PE LNGVYGGSKAFVLAFSQSLHHELA +GVQVQ Sbjct: 122 TYAAVPGFVARGHGAVINIASIVAISPETLNGVYGGSKAFVLAFSQSLHHELADKGVQVQ 181 Query: 186 AVLPGATATDFWAIGGLPVEHLDPAIVMSAEQMVDAALVGFQRGELVTIPSLHEEDAWTG 245 AVLPGATAT+FW GGLP+EHL IVM+A MVDAAL+GF RGELVTIPSLH D W Sbjct: 182 AVLPGATATEFWQTGGLPLEHLPKEIVMTAPDMVDAALIGFDRGELVTIPSLHAGDEWEA 241 Query: 246 YEAARQALIARLSANTPAPRYRAA 269 YEAAR+ + LSANTPAPRY AA Sbjct: 242 YEAARRTMAPHLSANTPAPRYTAA 265 >A9AKK8.1 A9AKK8_BURM1 Short-chain dehydrogenase/reductase SDR Length = 266 Score = 408 bits (1049), Expect = e-112, Method: Compositional matrix adjust. Identities = 205/261 (78%), Positives = 228/261 (87%) Query: 9 HRGTALVTGASSGIGAIYADRLARLGYDLILVARNRSRLNTLAERITNQTGRSVEVLEAD 68 HRGTA+VTGASSGIGAIYADRLAR GYDLILVAR+R+RL+ LA+RIT+ T RSVEV+EAD Sbjct: 5 HRGTAVVTGASSGIGAIYADRLARRGYDLILVARSRTRLDALAQRITSDTRRSVEVIEAD 64 Query: 69 LGQAASLAQVEEKLRSDASITLLVNNAGIGTHTPLLQSDVDHMTGMIALNVTAPTRLTYA 128 L A+LA VE KL+ DASITLLVNNAGIGTHTPLL+SDVD MT MI LNVTA TRLTYA Sbjct: 65 LNDRAALAAVEAKLKQDASITLLVNNAGIGTHTPLLESDVDAMTRMIDLNVTALTRLTYA 124 Query: 129 AVPGFVARGQGAVINISSIVGVAPEVLNGVYGGSKAFVLAFSQSLHHELAAQGVQVQAVL 188 AVPGFVARG GAVINI+SIV ++PE LNGVYGGSKAFVLAF+QSLHHELA +GVQVQAVL Sbjct: 125 AVPGFVARGHGAVINIASIVALSPETLNGVYGGSKAFVLAFTQSLHHELADKGVQVQAVL 184 Query: 189 PGATATDFWAIGGLPVEHLDPAIVMSAEQMVDAALVGFQRGELVTIPSLHEEDAWTGYEA 248 PGATATDFW GGLP+EHL +IVMSA MVDAALVGF+R ELVTIPSLH +AW YEA Sbjct: 185 PGATATDFWQTGGLPIEHLPKSIVMSASDMVDAALVGFERRELVTIPSLHAGEAWDAYEA 244 Query: 249 ARQALIARLSANTPAPRYRAA 269 AR+A+ LS++TPAPRY AA Sbjct: 245 ARRAMAPHLSSDTPAPRYAAA 265 >B1TF94.1 B1TF94_9BURK Short-chain dehydrogenase/reductase SDR Length = 266 Score = 408 bits (1049), Expect = e-112, Method: Compositional matrix adjust. Identities = 206/264 (78%), Positives = 223/264 (84%) Query: 6 TPAHRGTALVTGASSGIGAIYADRLARLGYDLILVARNRSRLNTLAERITNQTGRSVEVL 65 T AHRGTA++TGASSGIGAIYADRLAR GYDLILVARNR RL LAERITN T RSVE++ Sbjct: 2 TEAHRGTAVITGASSGIGAIYADRLARRGYDLILVARNRDRLTALAERITNDTQRSVEIV 61 Query: 66 EADLGQAASLAQVEEKLRSDASITLLVNNAGIGTHTPLLQSDVDHMTGMIALNVTAPTRL 125 ADL A+LA VE KL+ DASITLLVNNAG+GTH PLL SDVD MT MI LNVTA TRL Sbjct: 62 GADLNDRAALAAVEAKLKQDASITLLVNNAGVGTHAPLLDSDVDAMTRMIDLNVTALTRL 121 Query: 126 TYAAVPGFVARGQGAVINISSIVGVAPEVLNGVYGGSKAFVLAFSQSLHHELAAQGVQVQ 185 TYAAVPGFVARG+GAVINISSIV ++PE LNGVYGGSKAFVLAFSQSLHHELAA GVQVQ Sbjct: 122 TYAAVPGFVARGRGAVINISSIVALSPETLNGVYGGSKAFVLAFSQSLHHELAAHGVQVQ 181 Query: 186 AVLPGATATDFWAIGGLPVEHLDPAIVMSAEQMVDAALVGFQRGELVTIPSLHEEDAWTG 245 AVLPGATATDFW GGLP+EHL IVMSA +VDAALVGF+RGELVTIPSLH D W Sbjct: 182 AVLPGATATDFWQTGGLPLEHLPKEIVMSASDLVDAALVGFERGELVTIPSLHAADEWDA 241 Query: 246 YEAARQALIARLSANTPAPRYRAA 269 YEAAR+ + LS ++PAPRY AA Sbjct: 242 YEAARRTMAPHLSTDSPAPRYAAA 265