BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0273.p (298 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IWZ9.1 D8IWZ9_HERSS Permease of the drug/metabolite transporte... 563 e-158 B5SHD1.1 B5SHD1_RALSO Putative uncharacterized protein 191 1e-46 A3RYH4.1 A3RYH4_RALSO Transporter, drug/metabolite exporter family 191 1e-46 E2T0A0.1 E2T0A0_9RALS Membrane protein 184 1e-44 B2UB50.1 B2UB50_RALPJ Putative uncharacterized protein 184 1e-44 D8NQ64.1 D8NQ64_RALSO Putative uncharacterized protein 184 2e-44 B8KIF6.1 B8KIF6_9GAMM Transporter, drug/metabolite exporter family 182 5e-44 C6BCG0.1 C6BCG0_RALP1 Putative uncharacterized protein 181 1e-43 Q15P11.1 Q15P11_PSEA6 Putative uncharacterized protein 180 3e-43 C0Z4F0.1 C0Z4F0_BREBN Conserved hypothetical membrane protein 178 1e-42 >D8IWZ9.1 D8IWZ9_HERSS Permease of the drug/metabolite transporter (DMT) superfamily protein Length = 298 Score = 563 bits (1451), Expect = e-158, Method: Compositional matrix adjust. Identities = 297/298 (99%), Positives = 297/298 (99%) Query: 1 MSSSNLCKLLLLAAIWGTSFMLMRIAAPVFGPMLTTFGRASLATLALLAFARVRGVPMQW 60 MSSSNLCKLLLLAAIWGTSFMLMRIAAPVFGPMLTTFGRASLATLALLAFARVRGVPMQW Sbjct: 1 MSSSNLCKLLLLAAIWGTSFMLMRIAAPVFGPMLTTFGRASLATLALLAFARVRGVPMQW 60 Query: 61 RSNWLPYLVIGIFNTALPFALFAWSALHIPSAYMATMNSLALVFTAMFGFLLMGERLSLV 120 RSNWLPYLVIGIFNTALPFALFAWSALHIPSAYMATMNSLA VFTAMFGFLLMGERLSLV Sbjct: 61 RSNWLPYLVIGIFNTALPFALFAWSALHIPSAYMATMNSLAPVFTAMFGFLLMGERLSLV 120 Query: 121 RCAAFVLGLVGVAVLVGIGPAPADAMVIAGVLAAMGAAVSYGFAATFTRLRAGGISPIAL 180 RCAAFVLGLVGVAVLVGIGPAPADAMVIAGVLAAMGAAVSYGFAATFTRLRAGGISPIAL Sbjct: 121 RCAAFVLGLVGVAVLVGIGPAPADAMVIAGVLAAMGAAVSYGFAATFTRLRAGGISPIAL 180 Query: 181 ATGSQFAAALCLLPLAAPSMPHALQAGTLPALLAVLVLGVVCTGIAYALFFQLIAAEGAT 240 ATGSQFAAALCLLPLAAPSMPHALQAGTLPALLAVLVLGVVCTGIAYALFFQLIAAEGAT Sbjct: 181 ATGSQFAAALCLLPLAAPSMPHALQAGTLPALLAVLVLGVVCTGIAYALFFQLIAAEGAT 240 Query: 241 KAITVTFLVPMTASLWAWLLLDEPVTLGTVTGIAIVLVATATALRAKPAVAARTKATA 298 KAITVTFLVPMTASLWAWLLLDEPVTLGTVTGIAIVLVATATALRAKPAVAARTKATA Sbjct: 241 KAITVTFLVPMTASLWAWLLLDEPVTLGTVTGIAIVLVATATALRAKPAVAARTKATA 298 >B5SHD1.1 B5SHD1_RALSO Putative uncharacterized protein Length = 310 Score = 191 bits (485), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 120/281 (42%), Positives = 175/281 (62%), Gaps = 2/281 (0%) Query: 1 MSSSNLCKLLLLAAIWGTSFMLMRIAAPVFGPMLTTFGRASLATLALLAFARVRGVPMQW 60 M S++ +LL LAA+WG SF+ MR+AAP+FGP+ R ++A+ LL +RG Sbjct: 1 MRRSDVIELLTLAALWGGSFLFMRVAAPLFGPVALIALRVAIASAFLLPVLAMRGGLGAL 60 Query: 61 RSNWLPYLVIGIFNTALPFALFAWSALHIPSAYMATMNSLALVFTAMFGFLLMGERLSLV 120 R+ W L +GI N+A+PF LFA++ L + + + + +N+ A +F A+ F+ +GER+S Sbjct: 61 RAQWPHLLAVGILNSAIPFCLFAYAELTLTAGFTSVLNAAAPLFAAIVAFVWLGERMSSW 120 Query: 121 RCAAFVLGLVGVAVLVGIGPAPADAMVIAGVLAAMGAAVSYGFAATFTRLRAGGISPIAL 180 R +G VGV VLVG A V AA+GA V YG A+++T+ G+ P+A+ Sbjct: 121 RVLGLAIGFVGVIVLVGGSSALDAGQGGLAVAAALGATVLYGLASSYTKRHLTGVPPLAV 180 Query: 181 ATGSQFAAALCLLPLAAPSMPHALQAGTLPALLAVLVLGVVCTGIAYALFFQLIAAEGAT 240 ATGSQ AAA+ L PLA P G++ V+ LG+ CTGIAY LFF+L+A G T Sbjct: 181 ATGSQVAAAIVLAPLAVWLWPAHTPTGSV--WFHVIGLGIACTGIAYILFFRLVAHVGPT 238 Query: 241 KAITVTFLVPMTASLWAWLLLDEPVTLGTVTGIAIVLVATA 281 +A++VTFL+P+ LW L LDEP+TL V G A++L+ T+ Sbjct: 239 RAVSVTFLIPVFGVLWGILFLDEPLTLNMVAGCAVILLGTS 279 >A3RYH4.1 A3RYH4_RALSO Transporter, drug/metabolite exporter family Length = 310 Score = 191 bits (485), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 120/281 (42%), Positives = 175/281 (62%), Gaps = 2/281 (0%) Query: 1 MSSSNLCKLLLLAAIWGTSFMLMRIAAPVFGPMLTTFGRASLATLALLAFARVRGVPMQW 60 M S++ +LL LAA+WG SF+ MR+AAP+FGP+ R ++A+ LL +RG Sbjct: 1 MRRSDVIELLTLAALWGGSFLFMRVAAPLFGPVALIALRVAIASAFLLPVLAMRGGLGAL 60 Query: 61 RSNWLPYLVIGIFNTALPFALFAWSALHIPSAYMATMNSLALVFTAMFGFLLMGERLSLV 120 R+ W L +GI N+A+PF LFA++ L + + + + +N+ A +F A+ F+ +GER+S Sbjct: 61 RAQWPHLLAVGILNSAIPFCLFAYAELTLTAGFTSVLNAAAPLFAAIVAFVWLGERMSSW 120 Query: 121 RCAAFVLGLVGVAVLVGIGPAPADAMVIAGVLAAMGAAVSYGFAATFTRLRAGGISPIAL 180 R +G VGV VLVG A V AA+GA V YG A+++T+ G+ P+A+ Sbjct: 121 RVLGLAIGFVGVIVLVGGSSALDAGQGGLAVAAALGATVLYGLASSYTKRHLTGVPPLAV 180 Query: 181 ATGSQFAAALCLLPLAAPSMPHALQAGTLPALLAVLVLGVVCTGIAYALFFQLIAAEGAT 240 ATGSQ AAA+ L PLA P G++ V+ LG+ CTGIAY LFF+L+A G T Sbjct: 181 ATGSQVAAAIVLAPLAVWLWPAHTPTGSV--WFHVIGLGIACTGIAYILFFRLVAHVGPT 238 Query: 241 KAITVTFLVPMTASLWAWLLLDEPVTLGTVTGIAIVLVATA 281 +A++VTFL+P+ LW L LDEP+TL V G A++L+ T+ Sbjct: 239 RAVSVTFLIPVFGVLWGILFLDEPLTLNMVAGCAVILLGTS 279 >E2T0A0.1 E2T0A0_9RALS Membrane protein Length = 310 Score = 184 bits (468), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 117/282 (41%), Positives = 174/282 (61%), Gaps = 4/282 (1%) Query: 1 MSSSNLCKLLLLAAIWGTSFMLMRIAAPVFGPMLTTFGRASLATLALLAFARVRGVPMQW 60 M S++ +LL LAA+WG SF+ MR+AAP FGP+ R ++A+ L+ +RG Sbjct: 1 MRRSDVLELLTLAALWGGSFLFMRVAAPPFGPVALIALRVAIASCFLVPTLALRGGMGAL 60 Query: 61 RSNWLPYLVIGIFNTALPFALFAWSALHIPSAYMATMNSLALVFTAMFGFLLMGERLSLV 120 R++W L +G+ N+A+PF LFA++ L + + + + +N+ A +F A+ F +GER+S + Sbjct: 61 RTHWPHLLAVGVLNSAIPFCLFAYAELTLTAGFTSVLNAAAPLFAAIVAFTWLGERMSSL 120 Query: 121 RCAAFVLGLVGVAVLVGIGPAPADAMVIA-GVLAAMGAAVSYGFAATFTRLRAGGISPIA 179 R +G VGV VLVG G + DA V AA+ A V YG A+++T+ G+ P+A Sbjct: 121 RVLGLAIGFVGVIVLVG-GSSVIDAKQGGVAVAAALSATVLYGVASSYTKRFLTGVPPLA 179 Query: 180 LATGSQFAAALCLLPLAAPSMPHALQAGTLPALLAVLVLGVVCTGIAYALFFQLIAAEGA 239 +ATGSQ AA + L PLA P Q T L V+ LG+ CTG+AY LFF+L+A G Sbjct: 180 VATGSQVAATIVLAPLAYWLWPA--QTPTGGVWLHVIALGIACTGVAYILFFRLVAHVGP 237 Query: 240 TKAITVTFLVPMTASLWAWLLLDEPVTLGTVTGIAIVLVATA 281 T+A++VTFL+P+ LW L L E +TL V G A++L+ T+ Sbjct: 238 TRAVSVTFLIPVFGVLWGILFLGEQLTLNMVIGCAVILLGTS 279 >B2UB50.1 B2UB50_RALPJ Putative uncharacterized protein Length = 310 Score = 184 bits (468), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 114/282 (40%), Positives = 174/282 (61%), Gaps = 4/282 (1%) Query: 1 MSSSNLCKLLLLAAIWGTSFMLMRIAAPVFGPMLTTFGRASLATLALLAFARVRGVPMQW 60 M S++ +LL LAA+WG SF+ MR+AAP FGP+ R ++A+ L+ +RG Sbjct: 1 MRRSDVLELLTLAALWGGSFLFMRVAAPPFGPVALIALRVAIASCFLVPMLTLRGGMGAL 60 Query: 61 RSNWLPYLVIGIFNTALPFALFAWSALHIPSAYMATMNSLALVFTAMFGFLLMGERLSLV 120 R++W L +G+ N+A+PF LFA++ L + + + + +N+ A +F A+ F +GER+S + Sbjct: 61 RTHWPHLLAVGVLNSAIPFCLFAYAELTLTAGFTSVLNAAAPLFAAIVAFTWLGERMSSL 120 Query: 121 RCAAFVLGLVGVAVLVGIGPAPADAMVIA-GVLAAMGAAVSYGFAATFTRLRAGGISPIA 179 R +G +GV VLVG G + DA V AA+ A V YG A+++T+ G+ P+A Sbjct: 121 RVLGLAIGFIGVIVLVG-GSSVIDAKQGGVAVAAALSATVLYGVASSYTKRFLTGVPPLA 179 Query: 180 LATGSQFAAALCLLPLAAPSMPHALQAGTLPALLAVLVLGVVCTGIAYALFFQLIAAEGA 239 +ATGSQ AA+ L PLA P G++ L V+ LG+ CTG+AY LFF+L+A G Sbjct: 180 VATGSQLGAAIVLAPLAYWLWPAQTPTGSV--WLHVIALGIACTGVAYILFFRLVAHVGP 237 Query: 240 TKAITVTFLVPMTASLWAWLLLDEPVTLGTVTGIAIVLVATA 281 T+A++VTFL+P+ LW L L E +TL V G A++L+ + Sbjct: 238 TRAVSVTFLIPVFGVLWGILFLGEQLTLNMVIGCAVILLGAS 279 >D8NQ64.1 D8NQ64_RALSO Putative uncharacterized protein Length = 310 Score = 184 bits (466), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 119/281 (42%), Positives = 171/281 (60%), Gaps = 2/281 (0%) Query: 1 MSSSNLCKLLLLAAIWGTSFMLMRIAAPVFGPMLTTFGRASLATLALLAFARVRGVPMQW 60 M S++ +LL LAA+WG SF+ MR+AAP FGP+ R ++A+ LL +RG Sbjct: 1 MRRSDVLELLTLAALWGGSFLFMRVAAPPFGPVALIALRVAIASAFLLPVLAMRGGLGIL 60 Query: 61 RSNWLPYLVIGIFNTALPFALFAWSALHIPSAYMATMNSLALVFTAMFGFLLMGERLSLV 120 R+ W L +GI N+A+PF LFA++ L + + + + +N+ A +F A+ F +GER+S Sbjct: 61 RAQWPHLLAVGILNSAIPFCLFAYAELTLTAGFTSVLNAAAPLFAAIVAFAWLGERMSSW 120 Query: 121 RCAAFVLGLVGVAVLVGIGPAPADAMVIAGVLAAMGAAVSYGFAATFTRLRAGGISPIAL 180 R +G VGV VLVG A V AA+GA V YG A+++T+ G+ P+A+ Sbjct: 121 RVLGLAIGFVGVIVLVGGSSALDAGQGGLAVAAALGATVLYGLASSYTKRHLTGVPPLAV 180 Query: 181 ATGSQFAAALCLLPLAAPSMPHALQAGTLPALLAVLVLGVVCTGIAYALFFQLIAAEGAT 240 ATGSQ AAA+ L PLA P G + V+ LG+ CTGIAY LFF+L+A G T Sbjct: 181 ATGSQVAAAIVLAPLAVWLWPAHTPTGGV--WFHVIGLGIACTGIAYILFFRLVAHVGPT 238 Query: 241 KAITVTFLVPMTASLWAWLLLDEPVTLGTVTGIAIVLVATA 281 +A++VTFL+P+ LW L L EP+TL V G A++L+ T+ Sbjct: 239 RAVSVTFLIPVFGVLWGILFLHEPLTLNMVAGCAVILLGTS 279 >B8KIF6.1 B8KIF6_9GAMM Transporter, drug/metabolite exporter family Length = 298 Score = 182 bits (462), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 121/295 (41%), Positives = 171/295 (57%), Gaps = 7/295 (2%) Query: 1 MSSSNLCKLLLLAAIWGTSFMLMRIAAPVFGPMLTTFGRASLATLALLAFARVRGVPMQW 60 MS++ L +L+ LAAIWG+SFM MRIA P GP+ R A+L LL +R P+ Sbjct: 1 MSTAQLAQLVALAAIWGSSFMFMRIAVPQLGPVWLLEMRLVAASLILLIISRAMRRPLHL 60 Query: 61 RSNWLPYLVIGIFNTALPFALFAWSALHIPSAYMATMNSLALVFTAMFGFLLMGERLSLV 120 R +W Y+++G+FNTALPF FA++A +P++ +A +NS A ++ + GF+ G+ ++ Sbjct: 61 RKHWRHYVILGVFNTALPFWAFAYAAQTLPASMLAILNSTAPLWGLLIGFVWRGKPITRR 120 Query: 121 RCAAFVLGLVGVAVLVGIGPAPADAMVIAGVLAAMGAAVSYGFAATFTRLRAGGISPIAL 180 +LG+ GVA LVG+G + V+ AAV YG A+++ A + A Sbjct: 121 AIVGLLLGMSGVASLVGLGGLAVQPEALFAVILTASAAVCYGIASSYAE-YAEKVETYAN 179 Query: 181 ATGSQFAAALCLLPLA--APSMPHALQAGTLPALLAVLVLGVVCTGIAYALFFQLIAAEG 238 A GS +AA L LLP AP +P AG A+ A L+LGV+CTG+AY L+F LIA G Sbjct: 180 AHGSLWAATLLLLPFVPFAP-VPVEWPAG---AVAAALILGVLCTGVAYLLYFHLIATAG 235 Query: 239 ATKAITVTFLVPMTASLWAWLLLDEPVTLGTVTGIAIVLVATATALRAKPAVAAR 293 A A+TV +L+P+ LW WL LDE V L T+ G +VL T PA R Sbjct: 236 APSALTVGYLIPLWGVLWGWLFLDEAVGLHTLLGAGLVLSGTMLVTGFSPARMIR 290 >C6BCG0.1 C6BCG0_RALP1 Putative uncharacterized protein Length = 310 Score = 181 bits (459), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 115/282 (40%), Positives = 174/282 (61%), Gaps = 4/282 (1%) Query: 1 MSSSNLCKLLLLAAIWGTSFMLMRIAAPVFGPMLTTFGRASLATLALLAFARVRGVPMQW 60 M S++ +LL LAA+WG SF+ MR+AA FGP+ R ++A+ L+ +RG Sbjct: 1 MRRSDVLELLTLAALWGGSFLFMRVAALPFGPVALIALRVAIASCFLVPTLALRGGMGAL 60 Query: 61 RSNWLPYLVIGIFNTALPFALFAWSALHIPSAYMATMNSLALVFTAMFGFLLMGERLSLV 120 R++W L +G+ N+A+PF LFA++ L + + + + +N+ A +F A+ F +GER+S + Sbjct: 61 RTHWPHLLAVGVLNSAIPFCLFAYAELTLTAGFTSVLNAAAPLFAAIVAFTWLGERMSSL 120 Query: 121 RCAAFVLGLVGVAVLVGIGPAPADAMVIA-GVLAAMGAAVSYGFAATFTRLRAGGISPIA 179 R +G VGV VLVG G + DA V AA+ A V YG A+++T+ G+ P+A Sbjct: 121 RVLGLAIGFVGVIVLVG-GSSVIDAKQGGVAVAAALSATVLYGVASSYTKRFLTGVPPLA 179 Query: 180 LATGSQFAAALCLLPLAAPSMPHALQAGTLPALLAVLVLGVVCTGIAYALFFQLIAAEGA 239 +ATGSQ AA + L PLA P G++ L V+ LG+ CTG+AY LFF+L+A G Sbjct: 180 VATGSQVAATIVLAPLAYWLWPAQTPTGSV--WLHVIALGIACTGVAYILFFRLVAHVGP 237 Query: 240 TKAITVTFLVPMTASLWAWLLLDEPVTLGTVTGIAIVLVATA 281 T+A++VTFL+P+ LW L L E +TL V G A++L+ T+ Sbjct: 238 TRAVSVTFLIPVFGVLWGILFLGEQLTLNMVIGCAVILLGTS 279 >Q15P11.1 Q15P11_PSEA6 Putative uncharacterized protein Length = 300 Score = 180 bits (456), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 119/302 (39%), Positives = 173/302 (57%), Gaps = 14/302 (4%) Query: 1 MSSSNLCKLLLLAAIWGTSFMLMRIAAPVFGPMLTTFGRASLATLALLAFARVRGVPMQW 60 M + +L+LLA+IWG +F+ R A P FGP+ RAS+A+L LL F R Q Sbjct: 1 MQLRDFIELVLLASIWGAAFIFTRTATPEFGPISLITMRASIASLILLPFVCNRVAIRQI 60 Query: 61 RSNWLPYLVIGIFNTALPFALFAWSALHIPSAYMATMNSLALVFTAMFGFLLMGERLSLV 120 +W L++G+ NTA+PF LF++S LHI + Y + MN+ A +F AM G+L + +R+ V Sbjct: 61 TEHWRGILIVGLTNTAIPFCLFSYSLLHIGAGYASVMNATAPMFGAMIGWLWLKQRIPSV 120 Query: 121 RCAAFVLGLVGVAVLVGIGPAPADAMVIAGVLAAMGAAVSYGFAATFTRLRAGGISPIAL 180 ++G +GVAVL A D + I LA + A YG+A FT+ + P+AL Sbjct: 121 AVLGLLIGFLGVAVLSAAQAAAFDGISILPTLATLVATALYGYAGCFTKQHLSAVGPMAL 180 Query: 181 ATGSQFAAALCLLPLAAPSMPHALQAGTLPALLAVLVLGVVCTGIAYALFFQLIAAEGAT 240 A GS FAA LCLLPL MP L + + + + + LG +CT +AY ++F+LIA G + Sbjct: 181 AAGSLFAATLCLLPLNIWFMPSTLPSPS--SWVDAIALGALCTALAYLMYFRLIAKVGPS 238 Query: 241 KAITVTFLVPMTASLWAWLLLDEPVT----LGTVTGIAIVLVATATA--------LRAKP 288 A+TV +L+P LW +LL+E +T +G + I VL+ T A L+AKP Sbjct: 239 NALTVAYLIPAFGILWGIVLLNETLTPSMWVGVILVICGVLLVTGVASRVIAKRRLKAKP 298 Query: 289 AV 290 AV Sbjct: 299 AV 300 >C0Z4F0.1 C0Z4F0_BREBN Conserved hypothetical membrane protein Length = 300 Score = 178 bits (451), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 107/291 (36%), Positives = 173/291 (59%), Gaps = 2/291 (0%) Query: 1 MSSSNLCKLLLLAAIWGTSFMLMRIAAPVFGPMLTTFGRASLATLALLAFARVRGVPMQW 60 M S L L LAA+WG SF+ +RIA+PV GP LT GR ++A +ALL + G + Sbjct: 1 MKSKVLSALFCLAALWGASFLFIRIASPVLGPFLTIQGRVTIAAIALLIYTACIGRSADF 60 Query: 61 RSNWLPYLVIGIFNTALPFALFAWSALHIPSAYMATMNSLALVFTAMFGFLLMGERLSLV 120 +S W YL++G N A+PF L A +A+H+ ++ A +NSL VF+A+ + + E L+L Sbjct: 61 QSRWKQYLILGALNAAIPFMLIATAAIHLNASMSAILNSLTPVFSALVAWGWIKETLTLG 120 Query: 121 RCAAFVLGLVGVAVLVGIGPAPADAMVIAGVLAAMGAAVSYGFAATFTRLRAGGISPIAL 180 + ++G++GVA+LVG P VI V ++ + VSYGF + + G+ P+++ Sbjct: 121 KWVGIIVGIIGVAILVGWSSIPLTFEVIVAVGLSILSTVSYGFGGVYAKKALAGVPPLSV 180 Query: 181 ATGSQFAAALCLLPLAAPSMPHALQAGTLPALLAVLVLGVVCTGIAYALFFQLIAAEGAT 240 A G Q A++ L+P ++P ++ + T A+ +V+ + + CT IAY LFF LI+ G T Sbjct: 181 AVGQQIGASILLIPFTLFNLPTSMDSLTPAAIFSVVGVAIFCTAIAYPLFFYLISNAGPT 240 Query: 241 KAITVTFLVPMTASLWAWLLLDEPVTLGTVTGIAIVL--VATATALRAKPA 289 K +VT L+P+ +W + LDE +T G +TG+ ++L + +R +PA Sbjct: 241 KTQSVTLLIPLFGMIWGVVFLDETITAGMITGLIVILGSIFLIYDIRPQPA 291