BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0248.p (237 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IWX7.1 D8IWX7_HERSS Response regulator protein 477 e-133 C9YCY7.1 C9YCY7_9BURK Transcriptional regulatory protein ompR 353 9e-96 A6W3G3.1 A6W3G3_MARMS Two component transcriptional regulator, w... 260 1e-67 F2K036.1 F2K036_9GAMM Two component transcriptional regulator, w... 249 2e-64 A3YD78.1 A3YD78_9GAMM Response regulator 249 3e-64 C4L775.1 C4L775_TOLAT Two component transcriptional regulator, w... 242 4e-62 A1SX12.1 A1SX12_PSYIN Response regulator GltR 237 8e-61 E4PN92.1 E4PN92_MARAH Two component transcriptional regulator, w... 237 1e-60 A6EZA9.1 A6EZA9_9ALTE DNA-binding response regulator GltR 236 2e-60 D6CME7.1 D6CME7_THIS3 Transcriptional regulatory protein ompR 236 2e-60 >D8IWX7.1 D8IWX7_HERSS Response regulator protein Length = 237 Score = 477 bits (1227), Expect = e-133, Method: Compositional matrix adjust. Identities = 237/237 (100%), Positives = 237/237 (100%) Query: 1 MTRKILIVDDDQKTRTLLKAYLEKNQYEVRLAHDGATFLAEFQRLADELSLVILDVMLPD 60 MTRKILIVDDDQKTRTLLKAYLEKNQYEVRLAHDGATFLAEFQRLADELSLVILDVMLPD Sbjct: 1 MTRKILIVDDDQKTRTLLKAYLEKNQYEVRLAHDGATFLAEFQRLADELSLVILDVMLPD 60 Query: 61 TDGFALCKAVRRKSNVPVIMLTASSDETDRVVGLELGADDYIAKPYSPRELLARIKAIHR 120 TDGFALCKAVRRKSNVPVIMLTASSDETDRVVGLELGADDYIAKPYSPRELLARIKAIHR Sbjct: 61 TDGFALCKAVRRKSNVPVIMLTASSDETDRVVGLELGADDYIAKPYSPRELLARIKAIHR 120 Query: 121 RIGIDSSAAPRYYRFAGFSLDTVERTLVDSQGDIVPLTGMDYQLLKYFVEHPGDVLDRNV 180 RIGIDSSAAPRYYRFAGFSLDTVERTLVDSQGDIVPLTGMDYQLLKYFVEHPGDVLDRNV Sbjct: 121 RIGIDSSAAPRYYRFAGFSLDTVERTLVDSQGDIVPLTGMDYQLLKYFVEHPGDVLDRNV 180 Query: 181 LCEETRGRDAGPLDRSLDVQISKLRLRLNDGGRQPHLIKTVRGAGYVFSADVSAAAA 237 LCEETRGRDAGPLDRSLDVQISKLRLRLNDGGRQPHLIKTVRGAGYVFSADVSAAAA Sbjct: 181 LCEETRGRDAGPLDRSLDVQISKLRLRLNDGGRQPHLIKTVRGAGYVFSADVSAAAA 237 >C9YCY7.1 C9YCY7_9BURK Transcriptional regulatory protein ompR Length = 248 Score = 353 bits (907), Expect = 9e-96, Method: Compositional matrix adjust. Identities = 172/237 (72%), Positives = 202/237 (85%), Gaps = 1/237 (0%) Query: 1 MTRKILIVDDDQKTRTLLKAYLEKNQYEVRLAHDGATFLAEFQRLADELSLVILDVMLPD 60 MTR +L+VDDDQKTR LLK YLEK+QYEVR+AHDGA+F AEF+R DELSLVILDVMLPD Sbjct: 10 MTRTLLVVDDDQKTRNLLKTYLEKHQYEVRVAHDGASFNAEFERFKDELSLVILDVMLPD 69 Query: 61 TDGFALCKAVRRKSNVPVIMLTASSDETDRVVGLELGADDYIAKPYSPRELLARIKAIHR 120 TDGF LC++VR +S VP+IMLTAS+D+TDR+VGLELGADDYIAKPY+PRELLARIKAIHR Sbjct: 70 TDGFTLCRSVRSQSPVPIIMLTASADDTDRIVGLELGADDYIAKPYNPRELLARIKAIHR 129 Query: 121 RIGIDSSAAP-RYYRFAGFSLDTVERTLVDSQGDIVPLTGMDYQLLKYFVEHPGDVLDRN 179 R+ + + AP R+ +FAGFS+D VER L D QG V LT MD+ LL++F EH G+ LDR Sbjct: 130 RMQLGAPGAPVRFLKFAGFSMDMVERVLTDPQGQPVVLTSMDFNLLRFFAEHAGETLDRA 189 Query: 180 VLCEETRGRDAGPLDRSLDVQISKLRLRLNDGGRQPHLIKTVRGAGYVFSADVSAAA 236 L E+TRGRD GPLDRSLDVQ+S+LR RL+D G+QP LIKTVRG+GYVFSADVSA A Sbjct: 190 RLMEQTRGRDLGPLDRSLDVQVSRLRQRLHDDGKQPVLIKTVRGSGYVFSADVSAHA 246 >A6W3G3.1 A6W3G3_MARMS Two component transcriptional regulator, winged helix family Length = 244 Score = 260 bits (664), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 134/237 (56%), Positives = 171/237 (72%), Gaps = 7/237 (2%) Query: 5 ILIVDDDQKTRTLLKAYLEKNQYEVRLAHDGATFLAEFQRLADELSLVILDVMLPDTDGF 64 I +VDDD + RTLLK YLEK+Q+ V A G TFLA F R E+ LVILD+MLP DGF Sbjct: 7 IYVVDDDDEIRTLLKTYLEKHQFTVLTADSGETFLANF-RAEQEVDLVILDIMLPGQDGF 65 Query: 65 ALCKAVRRKSNVPVIMLTASSDETDRVVGLELGADDYIAKPYSPRELLARIKAIHRRIGI 124 A+C+++R +S VPVIMLTA+SDE DR++GLE+GADDY+AKP++PRELLARIKAI RR+ Sbjct: 66 AVCRSLRTQSQVPVIMLTANSDEMDRIIGLEIGADDYLAKPFNPRELLARIKAILRRMEH 125 Query: 125 DS--SAAP---RYYRFAGFSLDTVERTLVDSQGDIVPLTGMDYQLLKYFVEHPGDVLDRN 179 AP R+YRFA F+LDT+ R L + + L+G DY LL F+ HPG VL R Sbjct: 126 TEVVEIAPVTHRFYRFAQFTLDTLSRELY-FKDEKESLSGADYNLLMLFLTHPGAVLTRE 184 Query: 180 VLCEETRGRDAGPLDRSLDVQISKLRLRLNDGGRQPHLIKTVRGAGYVFSADVSAAA 236 ++ E TRGRD+ PLDR +DV +S+LR RL + RQP LIKT+RG GY+ +A V A + Sbjct: 185 LIAENTRGRDSAPLDRFIDVHVSRLRQRLREDARQPQLIKTIRGQGYILTASVEAIS 241 >F2K036.1 F2K036_9GAMM Two component transcriptional regulator, winged helix family Length = 298 Score = 249 bits (637), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 129/241 (53%), Positives = 169/241 (70%), Gaps = 12/241 (4%) Query: 2 TRKILIVDDDQKTRTLLKAYLEKNQYEVRLAHDGATFLAEFQRLAD-ELSLVILDVMLPD 60 +R + +VDDD R+LLK+YLE++Q++V A G FL +F AD + LVILDVMLP Sbjct: 54 SRYVYVVDDDNDIRSLLKSYLERHQFQVLTAESGEAFLEDFH--ADLNVELVILDVMLPG 111 Query: 61 TDGFALCKAVRRKSNVPVIMLTASSDETDRVVGLELGADDYIAKPYSPRELLARIKAIHR 120 DGFA+C+A+R +S VPVIMLTA+SDE DR++GLE+GADDY+AKP++PRELLAR+KAI R Sbjct: 112 QDGFAVCRALRTQSEVPVIMLTANSDEMDRIIGLEIGADDYLAKPFNPRELLARMKAILR 171 Query: 121 RI--------GIDSSAAPRYYRFAGFSLDTVERTLVDSQGDIVPLTGMDYQLLKYFVEHP 172 RI + + A RYY+FA F+LDT+ R L + LTG D+ LL F+ P Sbjct: 172 RIEPNDPIKEEQEKAKASRYYQFAQFTLDTLSREL-HHEDSKEALTGADFNLLMLFLASP 230 Query: 173 GDVLDRNVLCEETRGRDAGPLDRSLDVQISKLRLRLNDGGRQPHLIKTVRGAGYVFSADV 232 G VL R+ + E TRGRD+ PLDR +DV +S+LR RL + R P LIKTVRG GY+ +A V Sbjct: 231 GAVLSRDYIAENTRGRDSAPLDRFIDVHVSRLRQRLKEDARHPQLIKTVRGEGYIMTATV 290 Query: 233 S 233 Sbjct: 291 E 291 >A3YD78.1 A3YD78_9GAMM Response regulator Length = 264 Score = 249 bits (635), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 129/260 (49%), Positives = 168/260 (64%), Gaps = 24/260 (9%) Query: 1 MTRK--ILIVDDDQKTRTLLKAYLEKNQYEVRLAHDGATFLAEFQRLADELSLVILDVML 58 MTR + +VDDD + R LLK YLEK+Q+ VR A G +FLA+F++ + L+ILD+ML Sbjct: 1 MTRSKTVFVVDDDAEIRNLLKTYLEKHQFNVRTADSGESFLADFEQDS-AADLIILDIML 59 Query: 59 PDTDGFALCKAVRRKSNVPVIMLTASSDETDRVVGLELGADDYIAKPYSPRELLARIKAI 118 P DGF++C+++R KS VPVIMLTA+SDE DR++GLE+GADDY+AKP++PRELLAR+KAI Sbjct: 60 PGEDGFSVCRSLRMKSLVPVIMLTANSDEMDRIIGLEIGADDYLAKPFNPRELLARMKAI 119 Query: 119 HRRI---------------------GIDSSAAPRYYRFAGFSLDTVERTLVDSQGDIVPL 157 RRI S + R + FA F LD + R L G L Sbjct: 120 FRRIEQIALSQEVSTEGQQESQETHQKHSPSLQRRFSFADFCLDALSRELSHQDGTKCAL 179 Query: 158 TGMDYQLLKYFVEHPGDVLDRNVLCEETRGRDAGPLDRSLDVQISKLRLRLNDGGRQPHL 217 +G DY LL F+ +PG VL R + E TRGRD+ PLDR +DV IS+LR RLN+ R P L Sbjct: 180 SGADYNLLMLFLNNPGTVLSREYIAENTRGRDSAPLDRFIDVHISRLRQRLNEDARHPQL 239 Query: 218 IKTVRGAGYVFSADVSAAAA 237 IKT+RG GY+ + DV A Sbjct: 240 IKTIRGEGYILTVDVDCQDA 259 >C4L775.1 C4L775_TOLAT Two component transcriptional regulator, winged helix family Length = 240 Score = 242 bits (617), Expect = 4e-62, Method: Compositional matrix adjust. Identities = 123/236 (52%), Positives = 167/236 (70%), Gaps = 8/236 (3%) Query: 3 RKILIVDDDQKTRTLLKAYLEKNQYEVRLAHDGATFLAEFQRLA-DELSLVILDVMLPDT 61 + ILIVDDDQ+ R LLK YL + ++V A DG +Q+LA L+ILD+M+P Sbjct: 5 KPILIVDDDQEIRELLKEYLTRAGFDVLTACDGVEM---YQQLALSTPELIILDIMMPGD 61 Query: 62 DGFALCKAVRRKSNVPVIMLTASSDETDRVVGLELGADDYIAKPYSPRELLARIKAIHRR 121 DGF+LC+ +RRKS VP+IMLTA+SDE DRV+GLELGADDYIAKP+SPREL+ARIKA+ RR Sbjct: 62 DGFSLCQQIRRKSQVPIIMLTAASDEADRVIGLELGADDYIAKPFSPRELMARIKALLRR 121 Query: 122 IGI----DSSAAPRYYRFAGFSLDTVERTLVDSQGDIVPLTGMDYQLLKYFVEHPGDVLD 177 + R +FAG++LDT + L G + LTG D+ LL F++HPG VLD Sbjct: 122 AEFRQPEKEVVSGRKLKFAGWTLDTRTQLLTHEDGSGIDLTGSDFILLHLFLQHPGQVLD 181 Query: 178 RNVLCEETRGRDAGPLDRSLDVQISKLRLRLNDGGRQPHLIKTVRGAGYVFSADVS 233 R+ + + TRGR++ P++R +DVQIS+LR +L D G+ P +IKT+RG+GY+ A+V Sbjct: 182 RDTISDATRGRESLPMERGIDVQISRLRQKLGDNGKGPRIIKTIRGSGYMLIAEVE 237 >A1SX12.1 A1SX12_PSYIN Response regulator GltR Length = 241 Score = 237 bits (605), Expect = 8e-61, Method: Compositional matrix adjust. Identities = 119/237 (50%), Positives = 161/237 (67%), Gaps = 7/237 (2%) Query: 2 TRKILIVDDDQKTRTLLKAYLEKNQYEVRLAHDGATFLAEFQRLADELSLVILDVMLPDT 61 +++L++DDDQ R LL YL KN ++V A DG + QRL + L+ILD+MLP Sbjct: 4 NKQVLVIDDDQAIRELLAEYLSKNNFDVITAEDGLEM--DKQRLIHQPDLIILDIMLPGD 61 Query: 62 DGFALCKAVRRKSNVPVIMLTASSDETDRVVGLELGADDYIAKPYSPRELLARIKAIHRR 121 DGF LC+ +R+ S+VP+IMLTA+SDE DRV+GLE+GADDYIAKP+SPRELLARIKA+ RR Sbjct: 62 DGFILCQRIRQTSHVPIIMLTANSDEMDRVLGLEIGADDYIAKPFSPRELLARIKALLRR 121 Query: 122 IGIDS-----SAAPRYYRFAGFSLDTVERTLVDSQGDIVPLTGMDYQLLKYFVEHPGDVL 176 S SA RY F+ + LDT + L+D D + LTG D+QLL F+++ + Sbjct: 122 TQFASEENQPSAKARYLLFSNWKLDTKQHLLIDDNKDEISLTGADFQLLTLFLDNTNSAI 181 Query: 177 DRNVLCEETRGRDAGPLDRSLDVQISKLRLRLNDGGRQPHLIKTVRGAGYVFSADVS 233 R+ +C+ GRDA +R +DV +S+LR L D + P +IKT+RGAGYVF ADV+ Sbjct: 182 SRDQICQALHGRDAFANERGIDVHVSRLRQCLKDDAKSPKIIKTIRGAGYVFIADVN 238 >E4PN92.1 E4PN92_MARAH Two component transcriptional regulator, winged helix family Length = 246 Score = 237 bits (604), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 120/229 (52%), Positives = 156/229 (68%), Gaps = 2/229 (0%) Query: 5 ILIVDDDQKTRTLLKAYLEKNQYEVRLAHDGATFLAEFQRLADELSLVILDVMLPDTDGF 64 +L+VDDD R LL+ +L + Y+VR A DG + + L++LDVMLP DGF Sbjct: 16 VLVVDDDAAIRELLEEHLTRVGYDVRTAGDGDQMRERLN--SSHVDLIVLDVMLPGDDGF 73 Query: 65 ALCKAVRRKSNVPVIMLTASSDETDRVVGLELGADDYIAKPYSPRELLARIKAIHRRIGI 124 LC+ +R S VP+IMLTASSDETDRVVGLELGADDY+AKP+S REL AR+KA+ RR Sbjct: 74 TLCRQIREYSRVPIIMLTASSDETDRVVGLELGADDYLAKPFSARELQARVKALLRRASF 133 Query: 125 DSSAAPRYYRFAGFSLDTVERTLVDSQGDIVPLTGMDYQLLKYFVEHPGDVLDRNVLCEE 184 S PRY F + LDT+ L+D L+G D+ LL+ F+ HP +VLDR+ + + Sbjct: 134 SRSDNPRYVDFDRWRLDTLAHELIDENQQGTALSGADFALLQLFLSHPNEVLDRDTISDV 193 Query: 185 TRGRDAGPLDRSLDVQISKLRLRLNDGGRQPHLIKTVRGAGYVFSADVS 233 TRGR++ PLDR +DV +S+LR RL D GR P LIKTVRGAGY+ +A V+ Sbjct: 194 TRGRESMPLDRVVDVAVSRLRQRLGDQGRNPRLIKTVRGAGYLLAATVT 242 >A6EZA9.1 A6EZA9_9ALTE DNA-binding response regulator GltR Length = 238 Score = 236 bits (603), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 119/233 (51%), Positives = 158/233 (67%), Gaps = 2/233 (0%) Query: 4 KILIVDDDQKTRTLLKAYLEKNQYEVRLAHDGATFLAEFQRLADELSLVILDVMLPDTDG 63 IL+VDDD R LL +L + Y+V A +G + + L++LDVMLP DG Sbjct: 7 SILVVDDDLAIRELLHEHLSRVGYDVMTAAEGDSMRRTLSEA--RVDLIVLDVMLPGDDG 64 Query: 64 FALCKAVRRKSNVPVIMLTASSDETDRVVGLELGADDYIAKPYSPRELLARIKAIHRRIG 123 F LC+ +R S VP+IMLTASSDETDRVVGLE+GADDY+AKP+S REL AR+KA+ RR G Sbjct: 65 FTLCREIREHSQVPIIMLTASSDETDRVVGLEIGADDYLAKPFSARELQARVKALLRRSG 124 Query: 124 IDSSAAPRYYRFAGFSLDTVERTLVDSQGDIVPLTGMDYQLLKYFVEHPGDVLDRNVLCE 183 + + PR+ F + LDT L+ QG+ PL+G D+ LL+ F+ HP +VLDR+ + Sbjct: 125 FNRADNPRFVCFDRWRLDTQAHELISDQGETTPLSGADFSLLQLFLTHPNEVLDRDTISG 184 Query: 184 ETRGRDAGPLDRSLDVQISKLRLRLNDGGRQPHLIKTVRGAGYVFSADVSAAA 236 TRGR++ PLDR +DV +S+LR RL D GR P LIKTVRGAGY+ +A V+ + Sbjct: 185 VTRGRESMPLDRVVDVAVSRLRQRLGDQGRSPRLIKTVRGAGYLLAATVTHGS 237 >D6CME7.1 D6CME7_THIS3 Transcriptional regulatory protein ompR Length = 240 Score = 236 bits (603), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 127/236 (53%), Positives = 162/236 (68%), Gaps = 6/236 (2%) Query: 5 ILIVDDDQKTRTLLKAYLEKNQYEVRLAHDGATFLAEFQRLADELSLVILDVMLPDTDGF 64 ILIVDDD + R LL AYL+KN V DG E LA + L++LD+MLP DG Sbjct: 7 ILIVDDDAEIRRLLSAYLQKNGLRVTAVGDGKAM--ERALLASGVDLIVLDLMLPGDDGL 64 Query: 65 ALCKAVRRKSNVPVIMLTASSDETDRVVGLELGADDYIAKPYSPRELLARIKAIHRRI-G 123 LC+ +R KS++P++MLTA +ETDR+VGLE+GADDY+ KP+S RELLARIK I RR Sbjct: 65 TLCRNLRAKSDIPILMLTARGEETDRIVGLEMGADDYLPKPFSARELLARIKVILRRARS 124 Query: 124 IDSSAAP---RYYRFAGFSLDTVERTLVDSQGDIVPLTGMDYQLLKYFVEHPGDVLDRNV 180 + + P R RFAG++LDT R LV G +V L+G +Y+LL+ F+ HP VL+R+ Sbjct: 125 LPRNLQPEEARQVRFAGWTLDTAHRHLVSPAGVVVALSGAEYRLLRVFLSHPNRVLNRDQ 184 Query: 181 LCEETRGRDAGPLDRSLDVQISKLRLRLNDGGRQPHLIKTVRGAGYVFSADVSAAA 236 L + T+GR+A PLDRS+DVQ+S+LR RL D R P LIKTVRGAGYV SA V A Sbjct: 185 LVDLTQGREADPLDRSIDVQVSRLRQRLGDDPRDPALIKTVRGAGYVLSAPVEGTA 240