BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0189.p (308 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IWS8.1 D8IWS8_HERSS Metal-dependent hydrolase of the TIM-barre... 611 e-173 D8J114.1 D8J114_HERSS Metal-dependent hydrolase of the TIM-barre... 382 e-104 A2WG44.1 A2WG44_9BURK Putative uncharacterized protein 371 e-101 A4JJB4.1 A4JJB4_BURVG Amidohydrolase 2 365 4e-99 B9AYJ5.1 B9AYJ5_9BURK Amidohydrolase 2 362 4e-98 F0GA30.1 F0GA30_9BURK Amidohydrolase 2 362 4e-98 B9CDP7.1 B9CDP7_9BURK Amidohydrolase 2 361 7e-98 B9BRV0.1 B9BRV0_9BURK Amidohydrolase 2 361 7e-98 Q399X0.1 Q399X0_BURS3 Amidohydrolase 2 360 2e-97 A9ANE4.1 A9ANE4_BURM1 Putative amidohydrolase 359 4e-97 >D8IWS8.1 D8IWS8_HERSS Metal-dependent hydrolase of the TIM-barrel fold protein Length = 299 Score = 611 bits (1575), Expect = e-173, Method: Compositional matrix adjust. Identities = 299/299 (100%), Positives = 299/299 (100%) Query: 10 MPTPPAGRCKTPLRIDAHQHFWRYRSEDYPWIGAGMDLLAQDRLPYQFQPLLEAQGLHAS 69 MPTPPAGRCKTPLRIDAHQHFWRYRSEDYPWIGAGMDLLAQDRLPYQFQPLLEAQGLHAS Sbjct: 1 MPTPPAGRCKTPLRIDAHQHFWRYRSEDYPWIGAGMDLLAQDRLPYQFQPLLEAQGLHAS 60 Query: 70 ITVQARQGRDETAFLLEMARRDKRIAGIIGWEDLSAPDLAEQMERWGRHKLLGLRHQLQE 129 ITVQARQGRDETAFLLEMARRDKRIAGIIGWEDLSAPDLAEQMERWGRHKLLGLRHQLQE Sbjct: 61 ITVQARQGRDETAFLLEMARRDKRIAGIIGWEDLSAPDLAEQMERWGRHKLLGLRHQLQE 120 Query: 130 HDDANTLLTPAPLDQGVRWLQERSYTLDVLAHERHLPQLRQFCARHDQHWVVLNHLGKPA 189 HDDANTLLTPAPLDQGVRWLQERSYTLDVLAHERHLPQLRQFCARHDQHWVVLNHLGKPA Sbjct: 121 HDDANTLLTPAPLDQGVRWLQERSYTLDVLAHERHLPQLRQFCARHDQHWVVLNHLGKPA 180 Query: 190 LKEFRKGRAAFERWRQELRELTAMPHVACKISGLLTEADWLRGLCTRDFEHIVQCLDTAL 249 LKEFRKGRAAFERWRQELRELTAMPHVACKISGLLTEADWLRGLCTRDFEHIVQCLDTAL Sbjct: 181 LKEFRKGRAAFERWRQELRELTAMPHVACKISGLLTEADWLRGLCTRDFEHIVQCLDTAL 240 Query: 250 DLFGPQRLMFGSDWPVCLLAASYSRVVTVVREWSATRLCPSDQDALWGESSARIYGLLT 308 DLFGPQRLMFGSDWPVCLLAASYSRVVTVVREWSATRLCPSDQDALWGESSARIYGLLT Sbjct: 241 DLFGPQRLMFGSDWPVCLLAASYSRVVTVVREWSATRLCPSDQDALWGESSARIYGLLT 299 >D8J114.1 D8J114_HERSS Metal-dependent hydrolase of the TIM-barrel fold protein Length = 289 Score = 382 bits (980), Expect = e-104, Method: Compositional matrix adjust. Identities = 178/286 (62%), Positives = 224/286 (78%) Query: 21 PLRIDAHQHFWRYRSEDYPWIGAGMDLLAQDRLPYQFQPLLEAQGLHASITVQARQGRDE 80 P RIDAHQHFW Y+ + YPWIGAGM+LLA DR P Q QPLL+A+GL SI VQAR GR+E Sbjct: 3 PPRIDAHQHFWFYQPQAYPWIGAGMELLACDRTPGQLQPLLDAEGLGQSIAVQARAGREE 62 Query: 81 TAFLLEMARRDKRIAGIIGWEDLSAPDLAEQMERWGRHKLLGLRHQLQEHDDANTLLTPA 140 T FLLE+AR ++RIAG++GWEDL++P LA +ERWGR KL+G RHQLQ+ D + Sbjct: 63 TGFLLELARGNRRIAGVVGWEDLASPHLAANVERWGRDKLVGFRHQLQDEADVGGCVDAP 122 Query: 141 PLDQGVRWLQERSYTLDVLAHERHLPQLRQFCARHDQHWVVLNHLGKPALKEFRKGRAAF 200 + GV WLQ + DVL + R + +++ FCARHD+HW+VL+HLGKPAL EF +G AF Sbjct: 123 AFNAGVAWLQRQGMVYDVLVYARQMAEVQAFCARHDRHWLVLDHLGKPALTEFGRGDTAF 182 Query: 201 ERWRQELRELTAMPHVACKISGLLTEADWLRGLCTRDFEHIVQCLDTALDLFGPQRLMFG 260 E W+++LR L A+PHVACK+SGL+TEADW RGL +DF++I CLDTAL+ FGPQRLMFG Sbjct: 183 EGWQRQLRALAALPHVACKLSGLVTEADWQRGLRQKDFDNISLCLDTALEAFGPQRLMFG 242 Query: 261 SDWPVCLLAASYSRVVTVVREWSATRLCPSDQDALWGESSARIYGL 306 SDWPVCLLAASY++V VVREW+ATRL ++Q+ LWG ++AR YGL Sbjct: 243 SDWPVCLLAASYAKVAGVVREWAATRLSAAEQELLWGATAARCYGL 288 >A2WG44.1 A2WG44_9BURK Putative uncharacterized protein Length = 296 Score = 371 bits (952), Expect = e-101, Method: Compositional matrix adjust. Identities = 175/285 (61%), Positives = 211/285 (74%) Query: 22 LRIDAHQHFWRYRSEDYPWIGAGMDLLAQDRLPYQFQPLLEAQGLHASITVQARQGRDET 81 LRID+HQHFWRYR+ DYPWIGAGMD+LA+D LP +PL+ AQ L ASI VQAR GRDET Sbjct: 4 LRIDSHQHFWRYRAADYPWIGAGMDVLARDYLPDALRPLMHAQALGASIAVQARAGRDET 63 Query: 82 AFLLEMARRDKRIAGIIGWEDLSAPDLAEQMERWGRHKLLGLRHQLQEHDDANTLLTPAP 141 AFLLE+AR D RIA ++GWED+ APDLAE++ W KL G RHQLQ+ D + Sbjct: 64 AFLLELARDDARIAAVVGWEDIGAPDLAERVAEWRSPKLRGFRHQLQDEADVRAFVADPG 123 Query: 142 LDQGVRWLQERSYTLDVLAHERHLPQLRQFCARHDQHWVVLNHLGKPALKEFRKGRAAFE 201 ++GV WLQ Y DVL ER LP +R+FCARHD HW+VL+H GKPAL F + A Sbjct: 124 FERGVAWLQANGYVYDVLVFERQLPDVREFCARHDAHWLVLDHAGKPALAAFDRDDTALA 183 Query: 202 RWRQELRELTAMPHVACKISGLLTEADWLRGLCTRDFEHIVQCLDTALDLFGPQRLMFGS 261 RWR +LREL AMPHVACK+SGL+TEADW RGL +D H+ QCLD ALD FGPQRLMFGS Sbjct: 184 RWRTQLRELGAMPHVACKLSGLVTEADWRRGLRAQDVRHVEQCLDAALDAFGPQRLMFGS 243 Query: 262 DWPVCLLAASYSRVVTVVREWSATRLCPSDQDALWGESSARIYGL 306 DWPVCLLAASY V ++V W+ +RL +++ ALWG ++AR Y + Sbjct: 244 DWPVCLLAASYDEVASIVERWAESRLSAAERGALWGGTAARCYDV 288 >A4JJB4.1 A4JJB4_BURVG Amidohydrolase 2 Length = 296 Score = 365 bits (937), Expect = 4e-99, Method: Compositional matrix adjust. Identities = 173/287 (60%), Positives = 206/287 (71%) Query: 20 TPLRIDAHQHFWRYRSEDYPWIGAGMDLLAQDRLPYQFQPLLEAQGLHASITVQARQGRD 79 + +RID+HQHFWRYR+ DYPWIG MD LA+D LP P L A L ASI VQAR GRD Sbjct: 2 SAVRIDSHQHFWRYRAADYPWIGPAMDALARDYLPAALWPQLHAHALAASIAVQARAGRD 61 Query: 80 ETAFLLEMARRDKRIAGIIGWEDLSAPDLAEQMERWGRHKLLGLRHQLQEHDDANTLLTP 139 ETAFLLE+AR D RIA ++GWEDL+AP+LAE++ W KL G RHQLQ+ D + Sbjct: 62 ETAFLLELARDDARIAAVVGWEDLAAPELAERVAAWRSPKLRGFRHQLQDEADVAAFVGQ 121 Query: 140 APLDQGVRWLQERSYTLDVLAHERHLPQLRQFCARHDQHWVVLNHLGKPALKEFRKGRAA 199 ++GV WLQ Y DVL ER L +R FC RHD HW+VL+H GKPAL EF + A Sbjct: 122 PAFNRGVAWLQRHGYVYDVLVFERQLRDVRAFCTRHDAHWLVLDHAGKPALAEFDRDATA 181 Query: 200 FERWRQELRELTAMPHVACKISGLLTEADWLRGLCTRDFEHIVQCLDTALDLFGPQRLMF 259 F RWR ELREL A+PHV CK+SGL+TEADW RGLC D H+ QCLD AL FGPQRLMF Sbjct: 182 FARWRAELRELAALPHVVCKLSGLVTEADWRRGLCAPDLRHVEQCLDAALAAFGPQRLMF 241 Query: 260 GSDWPVCLLAASYSRVVTVVREWSATRLCPSDQDALWGESSARIYGL 306 GSDWPVCLLAASY V ++V W+A RL P+++DALWG ++AR Y + Sbjct: 242 GSDWPVCLLAASYDEVASLVERWAAARLSPAERDALWGGTAARCYAV 288 >B9AYJ5.1 B9AYJ5_9BURK Amidohydrolase 2 Length = 296 Score = 362 bits (929), Expect = 4e-98, Method: Compositional matrix adjust. Identities = 174/285 (61%), Positives = 205/285 (71%) Query: 22 LRIDAHQHFWRYRSEDYPWIGAGMDLLAQDRLPYQFQPLLEAQGLHASITVQARQGRDET 81 LRID+HQHFWRYR+ DYPWIGAGM +LA+D LP PL+ AQ L ASI VQAR GRDET Sbjct: 4 LRIDSHQHFWRYRAADYPWIGAGMGVLARDYLPDALHPLMHAQALGASIAVQARAGRDET 63 Query: 82 AFLLEMARRDKRIAGIIGWEDLSAPDLAEQMERWGRHKLLGLRHQLQEHDDANTLLTPAP 141 AFLLE+AR + RIA ++GWEDL AP LAE++ W KL G RHQLQ+ D + A Sbjct: 64 AFLLELARDEARIAAVVGWEDLRAPQLAERVAEWRGTKLRGFRHQLQDEADVRAFVDDAD 123 Query: 142 LDQGVRWLQERSYTLDVLAHERHLPQLRQFCARHDQHWVVLNHLGKPALKEFRKGRAAFE 201 +GV WLQ Y DVL ER LP ++ FCARHD HW+VL+H GKPAL EF + A Sbjct: 124 FARGVAWLQANGYVYDVLVFERQLPDVQAFCARHDAHWLVLDHAGKPALAEFDRDDTALA 183 Query: 202 RWRQELRELTAMPHVACKISGLLTEADWLRGLCTRDFEHIVQCLDTALDLFGPQRLMFGS 261 RWR LREL A+PHV CK+SGL+TEADW RGL D HI QCLD ALD FGPQRLMFGS Sbjct: 184 RWRAALRELAALPHVVCKLSGLVTEADWRRGLRASDLRHIEQCLDAALDAFGPQRLMFGS 243 Query: 262 DWPVCLLAASYSRVVTVVREWSATRLCPSDQDALWGESSARIYGL 306 DWPVCLLAASY V ++V W+ +RL +++ ALWG ++AR Y L Sbjct: 244 DWPVCLLAASYDEVASLVERWAESRLSAAERSALWGGTAARCYAL 288 >F0GA30.1 F0GA30_9BURK Amidohydrolase 2 Length = 290 Score = 362 bits (929), Expect = 4e-98, Method: Compositional matrix adjust. Identities = 172/287 (59%), Positives = 209/287 (72%) Query: 22 LRIDAHQHFWRYRSEDYPWIGAGMDLLAQDRLPYQFQPLLEAQGLHASITVQARQGRDET 81 +RID+HQHFWRYR+ DYPWIG M +LA+D LP P + AQ L ASI VQAR GRDET Sbjct: 4 MRIDSHQHFWRYRAADYPWIGPSMRVLARDYLPDALWPQMHAQALDASIAVQARAGRDET 63 Query: 82 AFLLEMARRDKRIAGIIGWEDLSAPDLAEQMERWGRHKLLGLRHQLQEHDDANTLLTPAP 141 AFLL++AR D RIA ++GWEDL+AP LA+++ W KL G RHQ+Q+ DA + + Sbjct: 64 AFLLDLARDDARIAAVVGWEDLAAPALADRVAEWRSPKLRGFRHQVQDEADAGAFVADSG 123 Query: 142 LDQGVRWLQERSYTLDVLAHERHLPQLRQFCARHDQHWVVLNHLGKPALKEFRKGRAAFE 201 ++GV WLQ Y DVL ER LP +R FCARHD HW+VL+H+GKPAL EF + A Sbjct: 124 FNRGVAWLQANGYVYDVLVFERQLPDVRAFCARHDAHWLVLDHVGKPALAEFERDETAQV 183 Query: 202 RWRQELRELTAMPHVACKISGLLTEADWLRGLCTRDFEHIVQCLDTALDLFGPQRLMFGS 261 RWR LREL AMPHVACK+SGL+TE DW RGL +D HI QCLD ALD FGPQRLMFGS Sbjct: 184 RWRASLRELGAMPHVACKLSGLVTETDWKRGLRAQDIRHIEQCLDAALDAFGPQRLMFGS 243 Query: 262 DWPVCLLAASYSRVVTVVREWSATRLCPSDQDALWGESSARIYGLLT 308 DWPVCLLAASY V ++V W+ +RL +++ ALWG ++AR YGL T Sbjct: 244 DWPVCLLAASYDEVASLVERWAESRLSTAERKALWGGTAARCYGLST 290 >B9CDP7.1 B9CDP7_9BURK Amidohydrolase 2 Length = 296 Score = 361 bits (927), Expect = 7e-98, Method: Compositional matrix adjust. Identities = 173/285 (60%), Positives = 205/285 (71%) Query: 22 LRIDAHQHFWRYRSEDYPWIGAGMDLLAQDRLPYQFQPLLEAQGLHASITVQARQGRDET 81 LRID+HQHFWRYR+ DYPWIGAGM +LA+D LP PL+ AQ L ASI VQAR GRDET Sbjct: 4 LRIDSHQHFWRYRAADYPWIGAGMGVLARDYLPDALHPLMHAQALGASIAVQARAGRDET 63 Query: 82 AFLLEMARRDKRIAGIIGWEDLSAPDLAEQMERWGRHKLLGLRHQLQEHDDANTLLTPAP 141 AFLL++AR + RIA ++GWEDL AP LAE++ W KL G RHQLQ+ D + A Sbjct: 64 AFLLDLARDEARIAAVVGWEDLRAPQLAERVAEWRGTKLRGFRHQLQDEADVRAFVDDAD 123 Query: 142 LDQGVRWLQERSYTLDVLAHERHLPQLRQFCARHDQHWVVLNHLGKPALKEFRKGRAAFE 201 +GV WLQ Y DVL ER LP ++ FCARHD HW+VL+H GKPAL EF + A Sbjct: 124 FTRGVAWLQANGYVYDVLVFERQLPDVQAFCARHDAHWLVLDHAGKPALAEFDRDDTALA 183 Query: 202 RWRQELRELTAMPHVACKISGLLTEADWLRGLCTRDFEHIVQCLDTALDLFGPQRLMFGS 261 RWR LREL A+PHV CK+SGL+TEADW RGL D HI QCLD ALD FGPQRLMFGS Sbjct: 184 RWRAALRELAALPHVVCKLSGLVTEADWRRGLRASDIRHIEQCLDAALDAFGPQRLMFGS 243 Query: 262 DWPVCLLAASYSRVVTVVREWSATRLCPSDQDALWGESSARIYGL 306 DWPVCLLAASY V ++V W+ +RL +++ ALWG ++AR Y L Sbjct: 244 DWPVCLLAASYDEVASLVERWAESRLSAAERSALWGGTAARCYAL 288 >B9BRV0.1 B9BRV0_9BURK Amidohydrolase 2 Length = 296 Score = 361 bits (927), Expect = 7e-98, Method: Compositional matrix adjust. Identities = 173/285 (60%), Positives = 205/285 (71%) Query: 22 LRIDAHQHFWRYRSEDYPWIGAGMDLLAQDRLPYQFQPLLEAQGLHASITVQARQGRDET 81 LRID+HQHFWRYR+ DYPWIGAGM +LA+D LP PL+ AQ L ASI VQAR GRDET Sbjct: 4 LRIDSHQHFWRYRAADYPWIGAGMGVLARDYLPDALHPLMHAQALGASIAVQARAGRDET 63 Query: 82 AFLLEMARRDKRIAGIIGWEDLSAPDLAEQMERWGRHKLLGLRHQLQEHDDANTLLTPAP 141 AFLL++AR + RIA ++GWEDL AP LAE++ W KL G RHQLQ+ D + A Sbjct: 64 AFLLDLARDEARIAAVVGWEDLRAPQLAERVAEWRGTKLRGFRHQLQDEADVRAFVDDAD 123 Query: 142 LDQGVRWLQERSYTLDVLAHERHLPQLRQFCARHDQHWVVLNHLGKPALKEFRKGRAAFE 201 +GV WLQ Y DVL ER LP ++ FCARHD HW+VL+H GKPAL EF + A Sbjct: 124 FTRGVAWLQANGYVYDVLVFERQLPDVQAFCARHDAHWLVLDHAGKPALAEFDRDDTALA 183 Query: 202 RWRQELRELTAMPHVACKISGLLTEADWLRGLCTRDFEHIVQCLDTALDLFGPQRLMFGS 261 RWR LREL A+PHV CK+SGL+TEADW RGL D HI QCLD ALD FGPQRLMFGS Sbjct: 184 RWRAALRELAALPHVVCKLSGLVTEADWRRGLRASDIRHIEQCLDAALDAFGPQRLMFGS 243 Query: 262 DWPVCLLAASYSRVVTVVREWSATRLCPSDQDALWGESSARIYGL 306 DWPVCLLAASY V ++V W+ +RL +++ ALWG ++AR Y L Sbjct: 244 DWPVCLLAASYDEVASLVERWAESRLSAAERSALWGGTAARCYAL 288 >Q399X0.1 Q399X0_BURS3 Amidohydrolase 2 Length = 290 Score = 360 bits (923), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 168/287 (58%), Positives = 211/287 (73%) Query: 22 LRIDAHQHFWRYRSEDYPWIGAGMDLLAQDRLPYQFQPLLEAQGLHASITVQARQGRDET 81 +RID+HQHFWRYR+ DYPWIGAGM +LA+D LP PL+ AQ + ASI VQAR GRDET Sbjct: 4 VRIDSHQHFWRYRAADYPWIGAGMGVLARDYLPDALWPLMHAQAIGASIAVQARAGRDET 63 Query: 82 AFLLEMARRDKRIAGIIGWEDLSAPDLAEQMERWGRHKLLGLRHQLQEHDDANTLLTPAP 141 AFLL++AR D RIA ++GWEDL+AP LA+++ W KL G RHQ+Q+ DA + Sbjct: 64 AFLLDLARDDARIAAVVGWEDLAAPQLADRVAEWRSPKLRGFRHQVQDEADAGAFVAAPD 123 Query: 142 LDQGVRWLQERSYTLDVLAHERHLPQLRQFCARHDQHWVVLNHLGKPALKEFRKGRAAFE 201 ++G+ WLQ Y DVLA E L + FCARHD HW+VL+H+GKPAL +F + A Sbjct: 124 FNRGIAWLQANGYVYDVLAFEHQLRDMWTFCARHDAHWLVLDHVGKPALADFERDDTALA 183 Query: 202 RWRQELRELTAMPHVACKISGLLTEADWLRGLCTRDFEHIVQCLDTALDLFGPQRLMFGS 261 RWR LREL A+PHVACK+SGL+TEADW RGL +D HI QCLD ALD FGPQRLMFGS Sbjct: 184 RWRAALRELGALPHVACKLSGLVTEADWKRGLRGKDVRHIEQCLDAALDAFGPQRLMFGS 243 Query: 262 DWPVCLLAASYSRVVTVVREWSATRLCPSDQDALWGESSARIYGLLT 308 DWPVCLLAASY V +++ W+ +RL ++++ALWG ++AR YG+ T Sbjct: 244 DWPVCLLAASYDEVASIIERWAESRLSAAERNALWGGTAARCYGVPT 290 >A9ANE4.1 A9ANE4_BURM1 Putative amidohydrolase Length = 296 Score = 359 bits (921), Expect = 4e-97, Method: Compositional matrix adjust. Identities = 173/285 (60%), Positives = 204/285 (71%) Query: 22 LRIDAHQHFWRYRSEDYPWIGAGMDLLAQDRLPYQFQPLLEAQGLHASITVQARQGRDET 81 LRID+HQHFWRYR+ DYPWIGAGM +LA+D LP PL+ AQ L ASI VQAR GRDET Sbjct: 4 LRIDSHQHFWRYRAADYPWIGAGMGVLARDYLPDALHPLMHAQALGASIAVQARAGRDET 63 Query: 82 AFLLEMARRDKRIAGIIGWEDLSAPDLAEQMERWGRHKLLGLRHQLQEHDDANTLLTPAP 141 AFLLE+A + RIA ++GWEDL AP LAE++ W KL G RHQLQ+ D + A Sbjct: 64 AFLLELACDEARIAAVVGWEDLRAPQLAERVAEWRGTKLRGFRHQLQDEADVRAFVDDAD 123 Query: 142 LDQGVRWLQERSYTLDVLAHERHLPQLRQFCARHDQHWVVLNHLGKPALKEFRKGRAAFE 201 +GV WLQ Y DVL ER LP ++ FCARHD HW+VL+H GKPAL EF + A Sbjct: 124 FARGVAWLQANDYVYDVLVFERQLPDVQAFCARHDAHWLVLDHAGKPALAEFDRDDTALA 183 Query: 202 RWRQELRELTAMPHVACKISGLLTEADWLRGLCTRDFEHIVQCLDTALDLFGPQRLMFGS 261 RWR LREL A+PHV CK+SGL+TEADW RGL D HI QCLD ALD FGPQRLMFGS Sbjct: 184 RWRAALRELAALPHVVCKLSGLVTEADWRRGLRASDLRHIEQCLDAALDAFGPQRLMFGS 243 Query: 262 DWPVCLLAASYSRVVTVVREWSATRLCPSDQDALWGESSARIYGL 306 DWPVCLLAASY V ++V W+ +RL +++ ALWG ++AR Y L Sbjct: 244 DWPVCLLAASYDEVASLVERWAESRLSAAERSALWGGTAARCYAL 288