BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0188.p (594 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IWS7.1 D8IWS7_HERSS Dihydroxyacid dehydratase/phosphogluconate... 1224 0.0 C0INI7.1 C0INI7_9BACT Xylonate dehydratase 1059 0.0 B0SWS0.1 B0SWS0_CAUSK Dihydroxy-acid dehydratase EC=4.2.1.9 967 0.0 D5VNB1.1 D5VNB1_CAUST Dihydroxy-acid dehydratase EC=4.2.1.9 959 0.0 B4RGG9.1 B4RGG9_PHEZH Dehydratase, IlvD/Edd family 957 0.0 Q9A9Z2.1 Q9A9Z2_CAUCR Dehydratase, IlvD/Edd family 956 0.0 B8H1Y8.1 B8H1Y8_CAUCN Xylonate dehydratase xylD 955 0.0 B9J8U0.1 B9J8U0_AGRRK Dihydroxy-acid dehydratase 941 0.0 E8RKN8.1 E8RKN8_9CAUL Dihydroxy-acid dehydratase EC=4.2.1.9 940 0.0 C6AUM7.1 C6AUM7_RHILS Dihydroxy-acid dehydratase EC=4.2.1.9 938 0.0 >D8IWS7.1 D8IWS7_HERSS Dihydroxyacid dehydratase/phosphogluconate dehydratase protein EC=4.2.1.9 Length = 594 Score = 1224 bits (3166), Expect = 0.0, Method: Compositional matrix adjust. Identities = 593/594 (99%), Positives = 594/594 (100%) Query: 1 MNKPNATPRRFRSQDWFDNPDHIDMTALYLERFMNYGITAEELRSGRPIIGIAQSGSDIS 60 MNKPNATPRRFRSQDWFDNPDHIDMTALYLERFMNYGITAEELRSGRPIIGIAQSGSDIS Sbjct: 1 MNKPNATPRRFRSQDWFDNPDHIDMTALYLERFMNYGITAEELRSGRPIIGIAQSGSDIS 60 Query: 61 PCNRIHLELAKRVRDGIRDAGGIPMEFPLHPIFENCRRPTAAIDRNLAYLGLVEILHGYP 120 PCNRIHLELAKRVRDGIRDAGGIPMEFPLHPIFENCRRPTAAIDRNLAYLGLVEILHGYP Sbjct: 61 PCNRIHLELAKRVRDGIRDAGGIPMEFPLHPIFENCRRPTAAIDRNLAYLGLVEILHGYP 120 Query: 121 IDAVVLTTGCDKTTPSQIMAAATVDIPAIVLSGGPMLDGWMDGELVGSGSAIWKGRKLLS 180 IDAVVLTTGCDKTTPSQIMAAATVDIPAIVLSGGPMLDGWMDGELVGSGSAIWKGRKLLS Sbjct: 121 IDAVVLTTGCDKTTPSQIMAAATVDIPAIVLSGGPMLDGWMDGELVGSGSAIWKGRKLLS 180 Query: 181 AGSIDNEKFLEIAAASAPSSGHCNTMGTASTMNAMAEALGMSLTGCSAIPAPYRERGQMA 240 AGSIDNEKFLEIAAASAPSSGHCNTMGTASTMNAMAEALGMSLTGCSAIPAPYRERGQMA Sbjct: 181 AGSIDNEKFLEIAAASAPSSGHCNTMGTASTMNAMAEALGMSLTGCSAIPAPYRERGQMA 240 Query: 241 YETGRRIVGMAYEDLRPSAILTRDAFLDAIVVNAAIGGSTNAQPHIMAMARHAGVELQSE 300 YETGRRIVGMAYEDLRPSAILTRDAFLDAIVVNAAIGGSTNAQPHIMAMARHAGVELQSE Sbjct: 241 YETGRRIVGMAYEDLRPSAILTRDAFLDAIVVNAAIGGSTNAQPHIMAMARHAGVELQSE 300 Query: 301 DWMKYGYDVPLLLNMQPAGKYLGERFHRAGGVPAIMWELQQAGKLRAERITASGKTMAEN 360 DWMKYGYDVPLLLNMQPAGKYLGERFHRAGGVPAIMWELQQAGKLRAERITA+GKTMAEN Sbjct: 301 DWMKYGYDVPLLLNMQPAGKYLGERFHRAGGVPAIMWELQQAGKLRAERITATGKTMAEN 360 Query: 361 LQGRASNDREMIYPFAAPLRERAGFLVLKGNLFDFAIMKTSVISETFRERYLSTPGQENI 420 LQGRASNDREMIYPFAAPLRERAGFLVLKGNLFDFAIMKTSVISETFRERYLSTPGQENI Sbjct: 361 LQGRASNDREMIYPFAAPLRERAGFLVLKGNLFDFAIMKTSVISETFRERYLSTPGQENI 420 Query: 421 FECRAVVFDGSDDYHARINDPALKIDENTLLAIRGAGPVGWPGSAEVVNMQPPDALIKRG 480 FECRAVVFDGSDDYHARINDPALKIDENTLLAIRGAGPVGWPGSAEVVNMQPPDALIKRG Sbjct: 421 FECRAVVFDGSDDYHARINDPALKIDENTLLAIRGAGPVGWPGSAEVVNMQPPDALIKRG 480 Query: 481 VSTLPTLGDGRQSGTSDSPSILNASPESAVGGGLAYLRDGDRVRIDLNTGECNMLVSEEE 540 VSTLPTLGDGRQSGTSDSPSILNASPESAVGGGLAYLRDGDRVRIDLNTGECNMLVSEEE Sbjct: 481 VSTLPTLGDGRQSGTSDSPSILNASPESAVGGGLAYLRDGDRVRIDLNTGECNMLVSEEE 540 Query: 541 LARRKSEGIPPVPPSQTPWQEIYRSTVGQLETGACMELALKYQGVAQTLPRHNH 594 LARRKSEGIPPVPPSQTPWQEIYRSTVGQLETGACMELALKYQGVAQTLPRHNH Sbjct: 541 LARRKSEGIPPVPPSQTPWQEIYRSTVGQLETGACMELALKYQGVAQTLPRHNH 594 >C0INI7.1 C0INI7_9BACT Xylonate dehydratase Length = 590 Score = 1059 bits (2738), Expect = 0.0, Method: Compositional matrix adjust. Identities = 495/588 (84%), Positives = 553/588 (94%) Query: 7 TPRRFRSQDWFDNPDHIDMTALYLERFMNYGITAEELRSGRPIIGIAQSGSDISPCNRIH 66 TPRRFRSQDWFDNPDHIDMTALYLERFMNYGIT +ELRSGRPIIGIAQSGSDISPCNRIH Sbjct: 3 TPRRFRSQDWFDNPDHIDMTALYLERFMNYGITPDELRSGRPIIGIAQSGSDISPCNRIH 62 Query: 67 LELAKRVRDGIRDAGGIPMEFPLHPIFENCRRPTAAIDRNLAYLGLVEILHGYPIDAVVL 126 LELAKRVRDGIRDAGGI MEFPLHPIFENCRRPTAAIDRNLAY+GLVEILHGYPIDAVVL Sbjct: 63 LELAKRVRDGIRDAGGIAMEFPLHPIFENCRRPTAAIDRNLAYMGLVEILHGYPIDAVVL 122 Query: 127 TTGCDKTTPSQIMAAATVDIPAIVLSGGPMLDGWMDGELVGSGSAIWKGRKLLSAGSIDN 186 TTGCDKTTP+Q+MAAATVDIPAIVLSGGPMLDGW+DGELVGSG+AIWKGR+ L+AG+I+ Sbjct: 123 TTGCDKTTPAQLMAAATVDIPAIVLSGGPMLDGWLDGELVGSGAAIWKGRRQLAAGAINE 182 Query: 187 EKFLEIAAASAPSSGHCNTMGTASTMNAMAEALGMSLTGCSAIPAPYRERGQMAYETGRR 246 EKFL+IAAASAPS+GHCNTMGTASTMNA+AEALGMSLTGCSAIPAPYRERGQMAYETG+R Sbjct: 183 EKFLQIAAASAPSAGHCNTMGTASTMNAIAEALGMSLTGCSAIPAPYRERGQMAYETGKR 242 Query: 247 IVGMAYEDLRPSAILTRDAFLDAIVVNAAIGGSTNAQPHIMAMARHAGVELQSEDWMKYG 306 IV MA++DLRPSAILTR+AFLDAIVVNAAIGGSTNAQ HI+AMARHAGVEL+S DWM+YG Sbjct: 243 IVEMAHQDLRPSAILTREAFLDAIVVNAAIGGSTNAQQHIVAMARHAGVELKSSDWMEYG 302 Query: 307 YDVPLLLNMQPAGKYLGERFHRAGGVPAIMWELQQAGKLRAERITASGKTMAENLQGRAS 366 + VPLLLNMQP+GK+LGERFHRAGGVPA+MWEL+Q GKLR++R+T +G TM++NL+GR + Sbjct: 303 HKVPLLLNMQPSGKFLGERFHRAGGVPAVMWELEQNGKLRSDRLTVTGATMSDNLKGRET 362 Query: 367 NDREMIYPFAAPLRERAGFLVLKGNLFDFAIMKTSVISETFRERYLSTPGQENIFECRAV 426 NDRE+IYP+AAPL+E AGF VLKGNLFDFAIMKTSVIS FR RYLS PGQEN+FE RAV Sbjct: 363 NDREVIYPYAAPLKEDAGFFVLKGNLFDFAIMKTSVISPEFRARYLSRPGQENVFEGRAV 422 Query: 427 VFDGSDDYHARINDPALKIDENTLLAIRGAGPVGWPGSAEVVNMQPPDALIKRGVSTLPT 486 VF+GS DYH RINDP+L IDE+++L IRGAGPVGWPGSAEVVNMQPPDALIKRG+ LPT Sbjct: 423 VFEGSGDYHERINDPSLNIDEDSILVIRGAGPVGWPGSAEVVNMQPPDALIKRGILNLPT 482 Query: 487 LGDGRQSGTSDSPSILNASPESAVGGGLAYLRDGDRVRIDLNTGECNMLVSEEELARRKS 546 LGDGRQSGTSDSPSILNASPESAVGGGLAY+ GD++R+DLN G C+ML+S+ E A RK+ Sbjct: 483 LGDGRQSGTSDSPSILNASPESAVGGGLAYIHTGDKIRVDLNQGTCDMLISDAEFAARKA 542 Query: 547 EGIPPVPPSQTPWQEIYRSTVGQLETGACMELALKYQGVAQTLPRHNH 594 +GIPP+PPSQTPWQ++YRSTVGQ+ETGACMELA+ Y+GV QTL RHNH Sbjct: 543 QGIPPIPPSQTPWQQLYRSTVGQMETGACMELAVDYRGVGQTLARHNH 590 >B0SWS0.1 B0SWS0_CAUSK Dihydroxy-acid dehydratase EC=4.2.1.9 Length = 597 Score = 967 bits (2500), Expect = 0.0, Method: Compositional matrix adjust. Identities = 445/587 (75%), Positives = 523/587 (89%), Gaps = 1/587 (0%) Query: 8 PRRFRSQDWFDNPDHIDMTALYLERFMNYGITAEELRSGRPIIGIAQSGSDISPCNRIHL 67 PRRFRS+DWFDNPDHIDMTALYLERFMNYGIT EELRSG+PIIGIAQ+GSDISPCNRIHL Sbjct: 12 PRRFRSRDWFDNPDHIDMTALYLERFMNYGITPEELRSGKPIIGIAQTGSDISPCNRIHL 71 Query: 68 ELAKRVRDGIRDAGGIPMEFPLHPIFENCRRPTAAIDRNLAYLGLVEILHGYPIDAVVLT 127 +L R+RDGIRDAGGIPMEFP+HPIFENCRRPTAA+DRNL+YLGLVE+LHGYPIDAVVLT Sbjct: 72 DLVTRIRDGIRDAGGIPMEFPVHPIFENCRRPTAALDRNLSYLGLVEVLHGYPIDAVVLT 131 Query: 128 TGCDKTTPSQIMAAATVDIPAIVLSGGPMLDGWMDGELVGSGSAIWKGRKLLSAGSIDNE 187 TGCDKTTP+ IMAA TV+IPAIVLSGGPMLDGW DGELVGSG+ IW+ R+ L+AG I+ E Sbjct: 132 TGCDKTTPAGIMAATTVNIPAIVLSGGPMLDGWHDGELVGSGTVIWRSRRKLAAGEINEE 191 Query: 188 KFLEIAAASAPSSGHCNTMGTASTMNAMAEALGMSLTGCSAIPAPYRERGQMAYETGRRI 247 +F++ A+ SAPS+GHCNTMGTASTMNA+AEALG+SLTGC+AIPAPYRERGQMAY+TG+RI Sbjct: 192 EFIQRASDSAPSAGHCNTMGTASTMNAVAEALGLSLTGCAAIPAPYRERGQMAYKTGQRI 251 Query: 248 VGMAYEDLRPSAILTRDAFLDAIVVNAAIGGSTNAQPHIMAMARHAGVELQSEDWMKYGY 307 V +AYED++P ILT+ AF +AI + AA GGSTNAQPHI+AMARHAG+++ ++DW + Y Sbjct: 252 VDLAYEDVKPLDILTKKAFENAIALVAAAGGSTNAQPHIVAMARHAGLDITADDW-RAAY 310 Query: 308 DVPLLLNMQPAGKYLGERFHRAGGVPAIMWELQQAGKLRAERITASGKTMAENLQGRASN 367 D+PL+LNMQPAGKYLGERFHRAGG PA++WEL QAG+L + +T +GKTM ENL+GR + Sbjct: 311 DIPLILNMQPAGKYLGERFHRAGGAPAVLWELLQAGRLHGDVMTVTGKTMGENLEGRETK 370 Query: 368 DREMIYPFAAPLRERAGFLVLKGNLFDFAIMKTSVISETFRERYLSTPGQENIFECRAVV 427 DRE+++P+ P+ ERAGFLVLKGNLFDFAIMKTSVIS+ FR+RYLS PG+E+ FE RAVV Sbjct: 371 DREVVFPYGQPMSERAGFLVLKGNLFDFAIMKTSVISQEFRQRYLSEPGKEDSFEARAVV 430 Query: 428 FDGSDDYHARINDPALKIDENTLLAIRGAGPVGWPGSAEVVNMQPPDALIKRGVSTLPTL 487 FDGSDDYHARINDP+L IDE T+L IRGAGP+GWPGSAEVVNMQPPDAL+KRG+ +LPTL Sbjct: 431 FDGSDDYHARINDPSLNIDERTILVIRGAGPIGWPGSAEVVNMQPPDALLKRGIMSLPTL 490 Query: 488 GDGRQSGTSDSPSILNASPESAVGGGLAYLRDGDRVRIDLNTGECNMLVSEEELARRKSE 547 GDGRQSGT+DSPSILNASPESA+GGGL++LR GD +RIDLNTG C+ LV E +A R+ E Sbjct: 491 GDGRQSGTADSPSILNASPESAIGGGLSWLRTGDMIRIDLNTGRCDALVDEATIAERRKE 550 Query: 548 GIPPVPPSQTPWQEIYRSTVGQLETGACMELALKYQGVAQTLPRHNH 594 G+PPVP + TPWQEIYR+ GQLETG +E A+KYQ +A LPRHNH Sbjct: 551 GVPPVPATMTPWQEIYRAHTGQLETGGVLEFAVKYQDLASKLPRHNH 597 >D5VNB1.1 D5VNB1_CAUST Dihydroxy-acid dehydratase EC=4.2.1.9 Length = 591 Score = 959 bits (2479), Expect = 0.0, Method: Compositional matrix adjust. Identities = 442/588 (75%), Positives = 519/588 (88%), Gaps = 1/588 (0%) Query: 7 TPRRFRSQDWFDNPDHIDMTALYLERFMNYGITAEELRSGRPIIGIAQSGSDISPCNRIH 66 TPRRFRS+DWFDNPDHIDMTALYLERFMNYGIT EELRSG+PIIGIAQ+GSDISPCNRIH Sbjct: 5 TPRRFRSRDWFDNPDHIDMTALYLERFMNYGITPEELRSGKPIIGIAQTGSDISPCNRIH 64 Query: 67 LELAKRVRDGIRDAGGIPMEFPLHPIFENCRRPTAAIDRNLAYLGLVEILHGYPIDAVVL 126 L+L R+RDGIRDAGGIPMEFP+HPIFENCRRPTAA+DRNL+YLGLVE LHGYPIDAVVL Sbjct: 65 LDLVTRIRDGIRDAGGIPMEFPVHPIFENCRRPTAALDRNLSYLGLVETLHGYPIDAVVL 124 Query: 127 TTGCDKTTPSQIMAAATVDIPAIVLSGGPMLDGWMDGELVGSGSAIWKGRKLLSAGSIDN 186 TTGCDKTTP+ IMAA TV+IPAIVLSGGPMLDGW +GELVGSG+ IW+ R+ L+AG I Sbjct: 125 TTGCDKTTPAGIMAATTVNIPAIVLSGGPMLDGWHEGELVGSGTVIWRSRRKLAAGEITE 184 Query: 187 EKFLEIAAASAPSSGHCNTMGTASTMNAMAEALGMSLTGCSAIPAPYRERGQMAYETGRR 246 E+F++ AA+SAPS+GHCNTMGTASTMNA+AEALG+SLTGC+AIPAPYRERGQMAY+TG+R Sbjct: 185 EEFIDRAASSAPSAGHCNTMGTASTMNAVAEALGLSLTGCAAIPAPYRERGQMAYKTGQR 244 Query: 247 IVGMAYEDLRPSAILTRDAFLDAIVVNAAIGGSTNAQPHIMAMARHAGVELQSEDWMKYG 306 IV +AYED++P ILT+ AF +AI + AA GGSTNAQPHI+AMARHAGVE+ ++DW + Sbjct: 245 IVDLAYEDVKPLDILTKKAFQNAIALVAAAGGSTNAQPHIVAMARHAGVEITADDW-RAA 303 Query: 307 YDVPLLLNMQPAGKYLGERFHRAGGVPAIMWELQQAGKLRAERITASGKTMAENLQGRAS 366 YD+PL++NMQPAGKYLGERFHRAGG PA++WEL Q G+L + +T +GKTM ENLQGR + Sbjct: 304 YDIPLIVNMQPAGKYLGERFHRAGGAPAVLWELLQQGRLHGDVLTVTGKTMGENLQGRET 363 Query: 367 NDREMIYPFAAPLRERAGFLVLKGNLFDFAIMKTSVISETFRERYLSTPGQENIFECRAV 426 +DRE+I+P+ PL E+AGFLVLKGNLFDFAIMK+SVI E FR+RYLS PG+E +FE RA+ Sbjct: 364 SDREVIFPYHQPLAEKAGFLVLKGNLFDFAIMKSSVIGEEFRKRYLSEPGKEGVFEARAI 423 Query: 427 VFDGSDDYHARINDPALKIDENTLLAIRGAGPVGWPGSAEVVNMQPPDALIKRGVSTLPT 486 VFDGSDDYH RINDPAL+IDE +L IRGAGP+GWPGSAEVVNMQPPD L+K+G+ +LPT Sbjct: 424 VFDGSDDYHKRINDPALEIDERCILVIRGAGPIGWPGSAEVVNMQPPDHLLKKGIMSLPT 483 Query: 487 LGDGRQSGTSDSPSILNASPESAVGGGLAYLRDGDRVRIDLNTGECNMLVSEEELARRKS 546 LGDGRQSGT+DSPSILNASPESA+GGGL++LR GD +RID+NTG C+ LV E +A RK Sbjct: 484 LGDGRQSGTADSPSILNASPESAIGGGLSWLRTGDTIRIDINTGRCDALVDEATIAERKK 543 Query: 547 EGIPPVPPSQTPWQEIYRSTVGQLETGACMELALKYQGVAQTLPRHNH 594 EGIP VP + TPWQEIYR+ GQLE+G +E A+KYQ +A LPRHNH Sbjct: 544 EGIPAVPATMTPWQEIYRAHTGQLESGGVLEFAVKYQDLASKLPRHNH 591 >B4RGG9.1 B4RGG9_PHEZH Dehydratase, IlvD/Edd family Length = 593 Score = 957 bits (2475), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/592 (76%), Positives = 522/592 (88%), Gaps = 1/592 (0%) Query: 4 PNATPRR-FRSQDWFDNPDHIDMTALYLERFMNYGITAEELRSGRPIIGIAQSGSDISPC 62 P+ P R FRS++WF P+ DMTALYLERFMNYGIT EEL+SGRPI+GIAQ+GSD+SPC Sbjct: 2 PDRKPARPFRSREWFAAPERSDMTALYLERFMNYGITPEELQSGRPIVGIAQTGSDLSPC 61 Query: 63 NRIHLELAKRVRDGIRDAGGIPMEFPLHPIFENCRRPTAAIDRNLAYLGLVEILHGYPID 122 NRIHL+LA+RVRDGIRDAGG+PMEFP+HPIFENCRRPTAA+DRNLAYLGL EIL+GYPID Sbjct: 62 NRIHLDLARRVRDGIRDAGGVPMEFPVHPIFENCRRPTAALDRNLAYLGLTEILYGYPID 121 Query: 123 AVVLTTGCDKTTPSQIMAAATVDIPAIVLSGGPMLDGWMDGELVGSGSAIWKGRKLLSAG 182 AVVLTTGCDKTTPS +MAA+TVDIPAIVLSGGPMLDGW +GELVGSG+ IW+ R+ L+AG Sbjct: 122 AVVLTTGCDKTTPSGVMAASTVDIPAIVLSGGPMLDGWHEGELVGSGTVIWRSRRKLAAG 181 Query: 183 SIDNEKFLEIAAASAPSSGHCNTMGTASTMNAMAEALGMSLTGCSAIPAPYRERGQMAYE 242 ID +FL A ASAPS+GHCNTMGTASTMNA+AEALG+SL GC+AIPAPYRERGQMAYE Sbjct: 182 EIDEAEFLRRATASAPSAGHCNTMGTASTMNAVAEALGLSLPGCAAIPAPYRERGQMAYE 241 Query: 243 TGRRIVGMAYEDLRPSAILTRDAFLDAIVVNAAIGGSTNAQPHIMAMARHAGVELQSEDW 302 TGRRIV MAYEDLRPS ILTR AFL+AI V +A GGS+NAQPHI+AMARHAGVEL EDW Sbjct: 242 TGRRIVDMAYEDLRPSKILTRAAFLNAIKVVSAAGGSSNAQPHIVAMARHAGVELSPEDW 301 Query: 303 MKYGYDVPLLLNMQPAGKYLGERFHRAGGVPAIMWELQQAGKLRAERITASGKTMAENLQ 362 M +GYDVPL++NMQPAGKYLGERFHRAGGVPA+MWEL +AG+L +T +G+T+AENL+ Sbjct: 302 MAHGYDVPLIVNMQPAGKYLGERFHRAGGVPAVMWELLRAGQLDGGCLTVTGRTLAENLE 361 Query: 363 GRASNDREMIYPFAAPLRERAGFLVLKGNLFDFAIMKTSVISETFRERYLSTPGQENIFE 422 GR ++DRE+I P+ PL+ERAGFLVLKGNLFDFAIMKTSVISE FR RYL+ PG+E +FE Sbjct: 362 GREASDREVITPYDQPLKERAGFLVLKGNLFDFAIMKTSVISEEFRARYLAEPGREGVFE 421 Query: 423 CRAVVFDGSDDYHARINDPALKIDENTLLAIRGAGPVGWPGSAEVVNMQPPDALIKRGVS 482 RAVVFDGS DYH RINDPAL IDE T+L IRG+GP+GWPGSAEVVNMQPPDALI+RG+S Sbjct: 422 ARAVVFDGSGDYHHRINDPALDIDERTILVIRGSGPLGWPGSAEVVNMQPPDALIQRGIS 481 Query: 483 TLPTLGDGRQSGTSDSPSILNASPESAVGGGLAYLRDGDRVRIDLNTGECNMLVSEEELA 542 +LPTLGDGRQSGTSDSPSILNASPESA GGGL++LR GD +RIDLNTG C+ LV E E+A Sbjct: 482 SLPTLGDGRQSGTSDSPSILNASPESAAGGGLSWLRTGDVIRIDLNTGRCDALVDEAEIA 541 Query: 543 RRKSEGIPPVPPSQTPWQEIYRSTVGQLETGACMELALKYQGVAQTLPRHNH 594 RRK+E PPVP S+TPW+E+YR GQL GA +E+A+KY+GV+ PRHNH Sbjct: 542 RRKAEAPPPVPESRTPWEELYREKTGQLAEGAVLEMAVKYRGVSAKTPRHNH 593 >Q9A9Z2.1 Q9A9Z2_CAUCR Dehydratase, IlvD/Edd family Length = 595 Score = 956 bits (2472), Expect = 0.0, Method: Compositional matrix adjust. Identities = 442/590 (74%), Positives = 520/590 (88%), Gaps = 1/590 (0%) Query: 5 NATPRRFRSQDWFDNPDHIDMTALYLERFMNYGITAEELRSGRPIIGIAQSGSDISPCNR 64 N TPRRFRS+DWFDNPDHIDMTALYLERFMNYGIT EELRSG+PIIGIAQ+GSDISPCNR Sbjct: 7 NRTPRRFRSRDWFDNPDHIDMTALYLERFMNYGITPEELRSGKPIIGIAQTGSDISPCNR 66 Query: 65 IHLELAKRVRDGIRDAGGIPMEFPLHPIFENCRRPTAAIDRNLAYLGLVEILHGYPIDAV 124 IHL+L +RVRDGIRDAGGIPMEFP+HPIFENCRRPTAA+DRNL+YLGLVE LHGYPIDAV Sbjct: 67 IHLDLVQRVRDGIRDAGGIPMEFPVHPIFENCRRPTAALDRNLSYLGLVETLHGYPIDAV 126 Query: 125 VLTTGCDKTTPSQIMAAATVDIPAIVLSGGPMLDGWMDGELVGSGSAIWKGRKLLSAGSI 184 VLTTGCDKTTP+ IMAA TV+IPAIVLSGGPMLDGW + ELVGSG+ IW+ R+ L+AG I Sbjct: 127 VLTTGCDKTTPAGIMAATTVNIPAIVLSGGPMLDGWHENELVGSGTVIWRSRRKLAAGEI 186 Query: 185 DNEKFLEIAAASAPSSGHCNTMGTASTMNAMAEALGMSLTGCSAIPAPYRERGQMAYETG 244 E+F++ AA+SAPS+GHCNTMGTASTMNA+AEALG+SLTGC+AIPAPYRERGQMAY+TG Sbjct: 187 TEEEFIDRAASSAPSAGHCNTMGTASTMNAVAEALGLSLTGCAAIPAPYRERGQMAYKTG 246 Query: 245 RRIVGMAYEDLRPSAILTRDAFLDAIVVNAAIGGSTNAQPHIMAMARHAGVELQSEDWMK 304 +RIV +AY+D++P ILT+ AF +AI + AA GGSTNAQPHI+AMARHAGVE+ ++DW + Sbjct: 247 QRIVDLAYDDVKPLDILTKQAFENAIALVAAAGGSTNAQPHIVAMARHAGVEITADDW-R 305 Query: 305 YGYDVPLLLNMQPAGKYLGERFHRAGGVPAIMWELQQAGKLRAERITASGKTMAENLQGR 364 YD+PL++NMQPAGKYLGERFHRAGG PA++WEL Q G+L + +T +GKTM+ENLQGR Sbjct: 306 AAYDIPLIVNMQPAGKYLGERFHRAGGAPAVLWELLQQGRLHGDVLTVTGKTMSENLQGR 365 Query: 365 ASNDREMIYPFAAPLRERAGFLVLKGNLFDFAIMKTSVISETFRERYLSTPGQENIFECR 424 ++DRE+I+P+ PL E+AGFLVLKGNLFDFAIMK+SVI E FR+RYLS PGQE +FE R Sbjct: 366 ETSDREVIFPYHEPLAEKAGFLVLKGNLFDFAIMKSSVIGEEFRKRYLSQPGQEGVFEAR 425 Query: 425 AVVFDGSDDYHARINDPALKIDENTLLAIRGAGPVGWPGSAEVVNMQPPDALIKRGVSTL 484 A+VFDGSDDYH RINDPAL+IDE +L IRGAGP+GWPGSAEVVNMQPPD L+K+G+ +L Sbjct: 426 AIVFDGSDDYHKRINDPALEIDERCILVIRGAGPIGWPGSAEVVNMQPPDHLLKKGIMSL 485 Query: 485 PTLGDGRQSGTSDSPSILNASPESAVGGGLAYLRDGDRVRIDLNTGECNMLVSEEELARR 544 PTLGDGRQSGT+DSPSILNASPESA+GGGL++LR GD +RIDLNTG C+ LV E +A R Sbjct: 486 PTLGDGRQSGTADSPSILNASPESAIGGGLSWLRTGDTIRIDLNTGRCDALVDEATIAAR 545 Query: 545 KSEGIPPVPPSQTPWQEIYRSTVGQLETGACMELALKYQGVAQTLPRHNH 594 K +GIP VP + TPWQEIYR+ QL+TG +E A+KYQ +A LPRHNH Sbjct: 546 KQDGIPAVPATMTPWQEIYRAHASQLDTGGVLEFAVKYQDLAAKLPRHNH 595 >B8H1Y8.1 B8H1Y8_CAUCN Xylonate dehydratase xylD Length = 591 Score = 955 bits (2469), Expect = 0.0, Method: Compositional matrix adjust. Identities = 442/590 (74%), Positives = 520/590 (88%), Gaps = 1/590 (0%) Query: 5 NATPRRFRSQDWFDNPDHIDMTALYLERFMNYGITAEELRSGRPIIGIAQSGSDISPCNR 64 N TPRRFRS+DWFDNPDHIDMTALYLERFMNYGIT EELRSG+PIIGIAQ+GSDISPCNR Sbjct: 3 NRTPRRFRSRDWFDNPDHIDMTALYLERFMNYGITPEELRSGKPIIGIAQTGSDISPCNR 62 Query: 65 IHLELAKRVRDGIRDAGGIPMEFPLHPIFENCRRPTAAIDRNLAYLGLVEILHGYPIDAV 124 IHL+L +RVRDGIRDAGGIPMEFP+HPIFENCRRPTAA+DRNL+YLGLVE LHGYPIDAV Sbjct: 63 IHLDLVQRVRDGIRDAGGIPMEFPVHPIFENCRRPTAALDRNLSYLGLVETLHGYPIDAV 122 Query: 125 VLTTGCDKTTPSQIMAAATVDIPAIVLSGGPMLDGWMDGELVGSGSAIWKGRKLLSAGSI 184 VLTTGCDKTTP+ IMAA TV+IPAIVLSGGPMLDGW + ELVGSG+ IW+ R+ L+AG I Sbjct: 123 VLTTGCDKTTPAGIMAATTVNIPAIVLSGGPMLDGWHENELVGSGTVIWRSRRKLAAGEI 182 Query: 185 DNEKFLEIAAASAPSSGHCNTMGTASTMNAMAEALGMSLTGCSAIPAPYRERGQMAYETG 244 E+F++ AA+SAPS+GHCNTMGTASTMNA+AEALG+SLTGC+AIPAPYRERGQMAY+TG Sbjct: 183 TEEEFIDRAASSAPSAGHCNTMGTASTMNAVAEALGLSLTGCAAIPAPYRERGQMAYKTG 242 Query: 245 RRIVGMAYEDLRPSAILTRDAFLDAIVVNAAIGGSTNAQPHIMAMARHAGVELQSEDWMK 304 +RIV +AY+D++P ILT+ AF +AI + AA GGSTNAQPHI+AMARHAGVE+ ++DW + Sbjct: 243 QRIVDLAYDDVKPLDILTKQAFENAIALVAAAGGSTNAQPHIVAMARHAGVEITADDW-R 301 Query: 305 YGYDVPLLLNMQPAGKYLGERFHRAGGVPAIMWELQQAGKLRAERITASGKTMAENLQGR 364 YD+PL++NMQPAGKYLGERFHRAGG PA++WEL Q G+L + +T +GKTM+ENLQGR Sbjct: 302 AAYDIPLIVNMQPAGKYLGERFHRAGGAPAVLWELLQQGRLHGDVLTVTGKTMSENLQGR 361 Query: 365 ASNDREMIYPFAAPLRERAGFLVLKGNLFDFAIMKTSVISETFRERYLSTPGQENIFECR 424 ++DRE+I+P+ PL E+AGFLVLKGNLFDFAIMK+SVI E FR+RYLS PGQE +FE R Sbjct: 362 ETSDREVIFPYHEPLAEKAGFLVLKGNLFDFAIMKSSVIGEEFRKRYLSQPGQEGVFEAR 421 Query: 425 AVVFDGSDDYHARINDPALKIDENTLLAIRGAGPVGWPGSAEVVNMQPPDALIKRGVSTL 484 A+VFDGSDDYH RINDPAL+IDE +L IRGAGP+GWPGSAEVVNMQPPD L+K+G+ +L Sbjct: 422 AIVFDGSDDYHKRINDPALEIDERCILVIRGAGPIGWPGSAEVVNMQPPDHLLKKGIMSL 481 Query: 485 PTLGDGRQSGTSDSPSILNASPESAVGGGLAYLRDGDRVRIDLNTGECNMLVSEEELARR 544 PTLGDGRQSGT+DSPSILNASPESA+GGGL++LR GD +RIDLNTG C+ LV E +A R Sbjct: 482 PTLGDGRQSGTADSPSILNASPESAIGGGLSWLRTGDTIRIDLNTGRCDALVDEATIAAR 541 Query: 545 KSEGIPPVPPSQTPWQEIYRSTVGQLETGACMELALKYQGVAQTLPRHNH 594 K +GIP VP + TPWQEIYR+ QL+TG +E A+KYQ +A LPRHNH Sbjct: 542 KQDGIPAVPATMTPWQEIYRAHASQLDTGGVLEFAVKYQDLAAKLPRHNH 591 >B9J8U0.1 B9J8U0_AGRRK Dihydroxy-acid dehydratase Length = 603 Score = 941 bits (2432), Expect = 0.0, Method: Compositional matrix adjust. Identities = 442/594 (74%), Positives = 508/594 (85%) Query: 1 MNKPNATPRRFRSQDWFDNPDHIDMTALYLERFMNYGITAEELRSGRPIIGIAQSGSDIS 60 M+ + + RR RSQDWFDNPDHIDMTALYLERFMNYGIT EELRSG+PIIGIAQSGSD++ Sbjct: 10 MSDNSPSKRRLRSQDWFDNPDHIDMTALYLERFMNYGITPEELRSGKPIIGIAQSGSDLT 69 Query: 61 PCNRIHLELAKRVRDGIRDAGGIPMEFPLHPIFENCRRPTAAIDRNLAYLGLVEILHGYP 120 PCNR H++LAKRVRDGIRDAGGIP+EFP HPIFENC+RPTAA+DRNLAYLGLVE+L+GYP Sbjct: 70 PCNRHHIDLAKRVRDGIRDAGGIPIEFPTHPIFENCKRPTAALDRNLAYLGLVEVLYGYP 129 Query: 121 IDAVVLTTGCDKTTPSQIMAAATVDIPAIVLSGGPMLDGWMDGELVGSGSAIWKGRKLLS 180 +D VVLTTGCDKTTPS +MAA+TV+IPAIVLSGGPMLDGW DGEL GSG+ IW+ R+ L+ Sbjct: 130 LDGVVLTTGCDKTTPSALMAASTVNIPAIVLSGGPMLDGWHDGELAGSGTVIWRSRRKLA 189 Query: 181 AGSIDNEKFLEIAAASAPSSGHCNTMGTASTMNAMAEALGMSLTGCSAIPAPYRERGQMA 240 AG ID E+F+E + ASAPS GHCNTMGTASTMNAMAEALGMSLTGC+AIP YRERGQMA Sbjct: 190 AGEIDEEEFMEASLASAPSIGHCNTMGTASTMNAMAEALGMSLTGCAAIPGAYRERGQMA 249 Query: 241 YETGRRIVGMAYEDLRPSAILTRDAFLDAIVVNAAIGGSTNAQPHIMAMARHAGVELQSE 300 Y TGRR V + E+++PS +LTR AFL+AI VN+AIGGSTNAQPH+ AMA+HAGVEL E Sbjct: 250 YRTGRRAVELVLENIKPSDVLTRQAFLNAIRVNSAIGGSTNAQPHLAAMAKHAGVELHPE 309 Query: 301 DWMKYGYDVPLLLNMQPAGKYLGERFHRAGGVPAIMWELQQAGKLRAERITASGKTMAEN 360 DW +G+D+PLL N+QPAG YLGERFHRAGGVPAIMWEL Q GKL + T +GKTMAEN Sbjct: 310 DWQVHGFDIPLLANVQPAGAYLGERFHRAGGVPAIMWELLQVGKLDGDCPTVTGKTMAEN 369 Query: 361 LQGRASNDREMIYPFAAPLRERAGFLVLKGNLFDFAIMKTSVISETFRERYLSTPGQENI 420 L+GR + DRE+I PFAAPL+ERAGFLVLKGNLFDFAIMK SV+SE FR RYL PG+E + Sbjct: 370 LKGREATDREVILPFAAPLKERAGFLVLKGNLFDFAIMKMSVVSEDFRSRYLQEPGREGV 429 Query: 421 FECRAVVFDGSDDYHARINDPALKIDENTLLAIRGAGPVGWPGSAEVVNMQPPDALIKRG 480 FE RAVVFDGS+DYH RIND L IDENT+L IRGAGP+GWPGSAEVVNMQPPDAL+KRG Sbjct: 430 FEGRAVVFDGSEDYHKRINDADLGIDENTILVIRGAGPIGWPGSAEVVNMQPPDALLKRG 489 Query: 481 VSTLPTLGDGRQSGTSDSPSILNASPESAVGGGLAYLRDGDRVRIDLNTGECNMLVSEEE 540 + +LPT+GDGRQSGT+DSPSILNASPESA GGGLA+LR GD +RID N G C+MLV E E Sbjct: 490 IRSLPTIGDGRQSGTADSPSILNASPESAAGGGLAWLRTGDTIRIDFNHGRCDMLVEEAE 549 Query: 541 LARRKSEGIPPVPPSQTPWQEIYRSTVGQLETGACMELALKYQGVAQTLPRHNH 594 + RRK +GIP VPP TPWQ IYR +V QL GA ++ A ++ +A PRHNH Sbjct: 550 IERRKGDGIPAVPPDATPWQRIYRRSVTQLSDGAVLDGAADFRDLAANPPRHNH 603 >E8RKN8.1 E8RKN8_9CAUL Dihydroxy-acid dehydratase EC=4.2.1.9 Length = 594 Score = 940 bits (2430), Expect = 0.0, Method: Compositional matrix adjust. Identities = 450/595 (75%), Positives = 514/595 (86%), Gaps = 2/595 (0%) Query: 1 MNKPNATPR-RFRSQDWFDNPDHIDMTALYLERFMNYGITAEELRSGRPIIGIAQSGSDI 59 M++ ATP RFRSQ+WF+ P HIDM ALYLERFMNYGIT +ELRSGRPIIGIAQSGSD+ Sbjct: 1 MSRKPATPNGRFRSQEWFEAPGHIDMAALYLERFMNYGITPQELRSGRPIIGIAQSGSDL 60 Query: 60 SPCNRIHLELAKRVRDGIRDAGGIPMEFPLHPIFENCRRPTAAIDRNLAYLGLVEILHGY 119 SPCNRIH++LA+RVR+GIRDAGGI MEFP HPIFENCRRPTAA+DRNL+++ LVEILHGY Sbjct: 61 SPCNRIHVDLAQRVREGIRDAGGICMEFPCHPIFENCRRPTAAVDRNLSFMTLVEILHGY 120 Query: 120 PIDAVVLTTGCDKTTPSQIMAAATVDIPAIVLSGGPMLDGWMDGELVGSGSAIWKGRKLL 179 P+DAVVLTTGCDKTTP+ IMAA VDIPAIVLSGGPMLDGW DG+LVGSG+ IW+ R+ L Sbjct: 121 PLDAVVLTTGCDKTTPAGIMAATAVDIPAIVLSGGPMLDGWHDGDLVGSGTVIWRSRRKL 180 Query: 180 SAGSIDNEKFLEIAAASAPSSGHCNTMGTASTMNAMAEALGMSLTGCSAIPAPYRERGQM 239 +AG I ++FLE A ASAPS+GHCNTMGTASTMNA+AE +G+SL GCSAIPAPYRERGQM Sbjct: 181 AAGEITEDEFLEAACASAPSAGHCNTMGTASTMNAVAETMGLSLPGCSAIPAPYRERGQM 240 Query: 240 AYETGRRIVGMAYEDLRPSAILTRDAFLDAIVVNAAIGGSTNAQPHIMAMARHAGVELQS 299 AYETGRRIV MAYEDL+PS ILT+ +FL+AI AA+GGSTNAQPHI+AMARHAGVEL Sbjct: 241 AYETGRRIVEMAYEDLKPSKILTKASFLNAIAAVAALGGSTNAQPHIVAMARHAGVELTP 300 Query: 300 EDWMKYGYDVPLLLNMQPAGKYLGERFHRAGGVPAIMWELQQAGKLRAERITASGKTMAE 359 EDWM YD+PL+LNMQPAGKYLGERFHRAGGVPAI EL +AG L T +GKT+AE Sbjct: 301 EDWMA-AYDIPLILNMQPAGKYLGERFHRAGGVPAIHVELLKAGMLDGTAATITGKTIAE 359 Query: 360 NLQGRASNDREMIYPFAAPLRERAGFLVLKGNLFDFAIMKTSVISETFRERYLSTPGQEN 419 N++GR + DREMI A PL ERAGFLVLKGNLFDFAIMKTSVIS FR+RYLS PG+E Sbjct: 360 NVEGRETRDREMIRTVAEPLMERAGFLVLKGNLFDFAIMKTSVISPEFRQRYLSEPGREG 419 Query: 420 IFECRAVVFDGSDDYHARINDPALKIDENTLLAIRGAGPVGWPGSAEVVNMQPPDALIKR 479 +FE RA+VFDGS DYH RINDPAL IDE+ +L IRG+GPVGWPGSAEVVNMQPPDAL+K+ Sbjct: 420 VFEGRAIVFDGSTDYHERINDPALNIDEHCILVIRGSGPVGWPGSAEVVNMQPPDALLKK 479 Query: 480 GVSTLPTLGDGRQSGTSDSPSILNASPESAVGGGLAYLRDGDRVRIDLNTGECNMLVSEE 539 G+++LPT+GDGRQSGT+DSPSILNASPESAVGGGLA+LR GD +RID+NTG C+MLVS E Sbjct: 480 GITSLPTIGDGRQSGTADSPSILNASPESAVGGGLAWLRTGDTIRIDINTGACDMLVSAE 539 Query: 540 ELARRKSEGIPPVPPSQTPWQEIYRSTVGQLETGACMELALKYQGVAQTLPRHNH 594 E+ +RKS+GIP P S T WQEIYR TVGQL TGA ME ALKY +A +PRHNH Sbjct: 540 EIEKRKSDGIPAYPESMTMWQEIYRQTVGQLHTGAVMEPALKYTKIADKMPRHNH 594 >C6AUM7.1 C6AUM7_RHILS Dihydroxy-acid dehydratase EC=4.2.1.9 Length = 594 Score = 938 bits (2424), Expect = 0.0, Method: Compositional matrix adjust. Identities = 440/594 (74%), Positives = 508/594 (85%) Query: 1 MNKPNATPRRFRSQDWFDNPDHIDMTALYLERFMNYGITAEELRSGRPIIGIAQSGSDIS 60 M ++ RR RSQDWFDNPDHIDM ALYLERFMNYGIT EELRSG+P+IGIAQSGSD++ Sbjct: 1 MTDSHSPKRRLRSQDWFDNPDHIDMAALYLERFMNYGITPEELRSGKPVIGIAQSGSDLT 60 Query: 61 PCNRIHLELAKRVRDGIRDAGGIPMEFPLHPIFENCRRPTAAIDRNLAYLGLVEILHGYP 120 PCNR+H+ELAKRVRDGIRDAGGIP+EFP HPIFENC+RPTAA+DRNLAYLGLVEIL+GYP Sbjct: 61 PCNRVHVELAKRVRDGIRDAGGIPIEFPTHPIFENCKRPTAALDRNLAYLGLVEILYGYP 120 Query: 121 IDAVVLTTGCDKTTPSQIMAAATVDIPAIVLSGGPMLDGWMDGELVGSGSAIWKGRKLLS 180 +D VVLTTGCDKTTPS IMAA+TVDIPAIVLSGGPMLDGW +GEL GSG+ IW+ R+ + Sbjct: 121 LDGVVLTTGCDKTTPSAIMAASTVDIPAIVLSGGPMLDGWHEGELAGSGTVIWRMRRKYA 180 Query: 181 AGSIDNEKFLEIAAASAPSSGHCNTMGTASTMNAMAEALGMSLTGCSAIPAPYRERGQMA 240 AG ID E+FL+ A SAPS GHCNTMGTASTMNA+AEALG+SLTGC AIPA YRERGQMA Sbjct: 181 AGEIDREEFLQAALDSAPSVGHCNTMGTASTMNALAEALGLSLTGCGAIPAAYRERGQMA 240 Query: 241 YETGRRIVGMAYEDLRPSAILTRDAFLDAIVVNAAIGGSTNAQPHIMAMARHAGVELQSE 300 Y TGRR V + +EDL+PS ILTR+AFL+AI N+AIGGSTNAQPH+ AMA+HAGVEL + Sbjct: 241 YRTGRRAVEIVFEDLKPSDILTREAFLNAIRTNSAIGGSTNAQPHLAAMAKHAGVELYPD 300 Query: 301 DWMKYGYDVPLLLNMQPAGKYLGERFHRAGGVPAIMWELQQAGKLRAERITASGKTMAEN 360 DW +G+D+PLL N+QPAG YLGERFHRAGG PAIMWEL QAGKL T +G+T+AEN Sbjct: 301 DWQVHGFDIPLLANVQPAGAYLGERFHRAGGTPAIMWELLQAGKLAGNCRTVTGRTIAEN 360 Query: 361 LQGRASNDREMIYPFAAPLRERAGFLVLKGNLFDFAIMKTSVISETFRERYLSTPGQENI 420 L+G+ + DRE+I PFA PL+ERAGFLVLKGNLFDFAIMK SV+SE FR RYL PG E + Sbjct: 361 LEGKEARDREVIKPFAEPLKERAGFLVLKGNLFDFAIMKMSVVSEDFRRRYLEEPGHEGV 420 Query: 421 FECRAVVFDGSDDYHARINDPALKIDENTLLAIRGAGPVGWPGSAEVVNMQPPDALIKRG 480 FE RAVVFDGS+DYH RINDP L IDENT+LAIRGAGP+GWPGSAEVVNMQPPD L+KRG Sbjct: 421 FEGRAVVFDGSEDYHKRINDPELGIDENTILAIRGAGPIGWPGSAEVVNMQPPDHLLKRG 480 Query: 481 VSTLPTLGDGRQSGTSDSPSILNASPESAVGGGLAYLRDGDRVRIDLNTGECNMLVSEEE 540 +S+LPT+GDGRQSGT+DSPSILNASPESA GGGLA+LR GD +RID N G C+MLV + E Sbjct: 481 ISSLPTIGDGRQSGTADSPSILNASPESAAGGGLAWLRTGDIIRIDFNHGRCDMLVEDAE 540 Query: 541 LARRKSEGIPPVPPSQTPWQEIYRSTVGQLETGACMELALKYQGVAQTLPRHNH 594 + RRK +GIPPVP TPWQ+IYR +V QL GA +E A +++ +A+ PRHNH Sbjct: 541 IERRKGDGIPPVPADATPWQQIYRRSVTQLSDGAVLEGAAEFRQIAKNPPRHNH 594