BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0069.p (173 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IVQ2.1 D8IVQ2_HERSS NADPH-quinone reductase (Modulator of drug... 351 2e-95 Q12E53.1 Q12E53_POLSJ Kef-type potassium/proton antiporter acces... 194 4e-48 E6V383.1 E6V383_VARPD NAD(P)H dehydrogenase (Quinone) 183 6e-45 C5CJV9.1 C5CJV9_VARPS NAD(P)H dehydrogenase (Quinone) 181 3e-44 Q0K5Y4.1 Q0K5Y4_CUPNH Glutathione-regulated potassium-efflux sys... 175 2e-42 Q1LHX7.1 Q1LHX7_RALME Glutathione-regulated potassium-efflux sys... 174 3e-42 B3R7V7.1 B3R7V7_CUPTR Glutathione-regulated potassium-efflux sys... 174 6e-42 Q8XUT8.1 Q8XUT8_RALSO Probable nad(P)h dehydrogenase (Quinone); ... 174 6e-42 D8NWF8.1 D8NWF8_RALSO Glutathione-regulated potassium-efflux sys... 171 4e-41 B2UFD2.1 B2UFD2_RALPJ NAD(P)H dehydrogenase (Quinone) 169 1e-40 >D8IVQ2.1 D8IVQ2_HERSS NADPH-quinone reductase (Modulator of drug activity B) protein EC=1.6.5.2 Length = 173 Score = 351 bits (901), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 173/173 (100%), Positives = 173/173 (100%) Query: 1 MPKALILYAHPTAELSRTNRLLLDAAARLPEVQIHDLYEHYPDFHIDVEHEQQLLGTVEL 60 MPKALILYAHPTAELSRTNRLLLDAAARLPEVQIHDLYEHYPDFHIDVEHEQQLLGTVEL Sbjct: 1 MPKALILYAHPTAELSRTNRLLLDAAARLPEVQIHDLYEHYPDFHIDVEHEQQLLGTVEL 60 Query: 61 IVMQHPIHWYSMPALQKQWLDSVLTRGWAFGHGGHALHGKRFWLVATTGGEEAAYRPQGR 120 IVMQHPIHWYSMPALQKQWLDSVLTRGWAFGHGGHALHGKRFWLVATTGGEEAAYRPQGR Sbjct: 61 IVMQHPIHWYSMPALQKQWLDSVLTRGWAFGHGGHALHGKRFWLVATTGGEEAAYRPQGR 120 Query: 121 HGHRFADFLPPYQQTAALCGMQWQEPLILHGAHHIPPEQFQRHLQHYLAGLQA 173 HGHRFADFLPPYQQTAALCGMQWQEPLILHGAHHIPPEQFQRHLQHYLAGLQA Sbjct: 121 HGHRFADFLPPYQQTAALCGMQWQEPLILHGAHHIPPEQFQRHLQHYLAGLQA 173 >Q12E53.1 Q12E53_POLSJ Kef-type potassium/proton antiporter accessory protein, CPA2 family Length = 242 Score = 194 bits (493), Expect = 4e-48, Method: Compositional matrix adjust. Identities = 92/168 (54%), Positives = 114/168 (67%) Query: 6 ILYAHPTAELSRTNRLLLDAAARLPEVQIHDLYEHYPDFHIDVEHEQQLLGTVELIVMQH 65 ++ AHP SR NR L++AA LP VQ+ DLY YPD+ IDV EQ L L+V+ H Sbjct: 25 VIAAHPAWRESRVNRPLMEAAKTLPRVQVQDLYSSYPDYAIDVAREQAALEQARLVVLLH 84 Query: 66 PIHWYSMPALQKQWLDSVLTRGWAFGHGGHALHGKRFWLVATTGGEEAAYRPQGRHGHRF 125 PI WYSMPALQK WLD VLT GWA+G GGHAL GK WLVATTGG E +Y PQG + + F Sbjct: 85 PIQWYSMPALQKLWLDDVLTYGWAYGQGGHALEGKDLWLVATTGGPETSYHPQGYNRYFF 144 Query: 126 ADFLPPYQQTAALCGMQWQEPLILHGAHHIPPEQFQRHLQHYLAGLQA 173 FLPPY+Q+A LCGM++ P++LH AH + E +HL + LQ+ Sbjct: 145 DAFLPPYEQSAILCGMRFLPPMVLHAAHRVSTEVVAQHLATFSQRLQS 192 >E6V383.1 E6V383_VARPD NAD(P)H dehydrogenase (Quinone) Length = 252 Score = 183 bits (465), Expect = 6e-45, Method: Compositional matrix adjust. Identities = 88/162 (54%), Positives = 109/162 (67%) Query: 6 ILYAHPTAELSRTNRLLLDAAARLPEVQIHDLYEHYPDFHIDVEHEQQLLGTVELIVMQH 65 ++ AHP SR NR +L AA +P V++ DLY YPDF IDVE EQ L L+V+ H Sbjct: 19 VIAAHPHWRDSRVNRRMLAAARAVPGVEVCDLYGSYPDFAIDVEAEQARLAKARLVVLVH 78 Query: 66 PIHWYSMPALQKQWLDSVLTRGWAFGHGGHALHGKRFWLVATTGGEEAAYRPQGRHGHRF 125 PI WYSMPALQK W+D VL+ GWA+G GG AL GK FWLVATTG E++Y PQ H + F Sbjct: 79 PIQWYSMPALQKLWVDDVLSYGWAYGPGGTALQGKDFWLVATTGSPESSYHPQNYHRYFF 138 Query: 126 ADFLPPYQQTAALCGMQWQEPLILHGAHHIPPEQFQRHLQHY 167 FLPPY+QTAALCGM++ PLI +GA + H++ Y Sbjct: 139 DAFLPPYEQTAALCGMRFLPPLIFYGARSADEAEVTAHVETY 180 >C5CJV9.1 C5CJV9_VARPS NAD(P)H dehydrogenase (Quinone) Length = 231 Score = 181 bits (459), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 88/162 (54%), Positives = 109/162 (67%) Query: 6 ILYAHPTAELSRTNRLLLDAAARLPEVQIHDLYEHYPDFHIDVEHEQQLLGTVELIVMQH 65 +L AHP SR NR +L AA +P V ++D+Y YPDF IDVE E L L+V+ H Sbjct: 16 VLAAHPHWRDSRVNRRMLAAARGVPGVDVNDIYGSYPDFSIDVEAEHARLARASLVVLLH 75 Query: 66 PIHWYSMPALQKQWLDSVLTRGWAFGHGGHALHGKRFWLVATTGGEEAAYRPQGRHGHRF 125 PI WYSMPALQK WLD VL+ GWA+G GG AL GK WLVATTG EA+Y PQ H + F Sbjct: 76 PIQWYSMPALQKLWLDDVLSYGWAYGPGGTALQGKDCWLVATTGSPEASYHPQSYHRYFF 135 Query: 126 ADFLPPYQQTAALCGMQWQEPLILHGAHHIPPEQFQRHLQHY 167 FLPPY+QTAALCGM++ PL+LHGA ++ H++ + Sbjct: 136 DAFLPPYEQTAALCGMRFLPPLVLHGARSAAEDEVAAHVEVF 177 >Q0K5Y4.1 Q0K5Y4_CUPNH Glutathione-regulated potassium-efflux system protein kefC Length = 177 Score = 175 bits (443), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 83/166 (50%), Positives = 104/166 (62%) Query: 6 ILYAHPTAELSRTNRLLLDAAARLPEVQIHDLYEHYPDFHIDVEHEQQLLGTVELIVMQH 65 ++YAHPT SR NR L DA A LP+VQ+ DLY Y D+ IDV EQ++L + IV+Q Sbjct: 1 MIYAHPTPSRSRVNRPLADALAALPQVQVRDLYRSYVDYDIDVVAEQRVLSVSDTIVLQF 60 Query: 66 PIHWYSMPALQKQWLDSVLTRGWAFGHGGHALHGKRFWLVATTGGEEAAYRPQGRHGHRF 125 P+ WYS+PAL K WLD VL GWA+G GG AL GK V +TGG +Y P G HGH Sbjct: 61 PVRWYSVPALLKLWLDEVLEPGWAYGPGGTALRGKSLLAVVSTGGTADSYGPDGTHGHPI 120 Query: 126 ADFLPPYQQTAALCGMQWQEPLILHGAHHIPPEQFQRHLQHYLAGL 171 DFL P +QTA LCGM W P++LH A++ + H+ H L Sbjct: 121 GDFLLPLEQTALLCGMSWLPPVVLHDANNADAQALAEHIAHVCGRL 166 >Q1LHX7.1 Q1LHX7_RALME Glutathione-regulated potassium-efflux system ancillary protein KefF (Modular protein) Length = 219 Score = 174 bits (442), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 83/165 (50%), Positives = 107/165 (64%) Query: 2 PKALILYAHPTAELSRTNRLLLDAAARLPEVQIHDLYEHYPDFHIDVEHEQQLLGTVELI 61 P ++++AHP+ SR NR L +A A LP V++ +LY Y D+ IDV EQ+LL T E + Sbjct: 27 PPVVVIFAHPSPRRSRVNRPLAEALAALPHVEVRELYRLYVDYDIDVVAEQRLLSTAETL 86 Query: 62 VMQHPIHWYSMPALQKQWLDSVLTRGWAFGHGGHALHGKRFWLVATTGGEEAAYRPQGRH 121 V+Q P+ WYS+PAL K WLD VL GWAFG GG AL GK V +TGG AY P+G H Sbjct: 87 VLQFPVRWYSVPALLKLWLDDVLESGWAFGPGGTALRGKSMLAVVSTGGHADAYGPEGTH 146 Query: 122 GHRFADFLPPYQQTAALCGMQWQEPLILHGAHHIPPEQFQRHLQH 166 GH ADFL P +QTA LCGM W P++LH A + + H++H Sbjct: 147 GHPIADFLLPLEQTALLCGMTWLPPVVLHDADNADSDAVALHIEH 191 >B3R7V7.1 B3R7V7_CUPTR Glutathione-regulated potassium-efflux system ancillary protein, putative quinone oxidoreductase flavoprotein Length = 177 Score = 174 bits (440), Expect = 6e-42, Method: Compositional matrix adjust. Identities = 83/166 (50%), Positives = 105/166 (63%) Query: 6 ILYAHPTAELSRTNRLLLDAAARLPEVQIHDLYEHYPDFHIDVEHEQQLLGTVELIVMQH 65 ++YAHPT SR NR L DA LP+VQ+ DLY Y D+ IDV EQ++L + IV+Q Sbjct: 1 MIYAHPTPSRSRVNRPLADALDSLPQVQVRDLYRRYVDYDIDVVAEQRVLSVSDTIVLQF 60 Query: 66 PIHWYSMPALQKQWLDSVLTRGWAFGHGGHALHGKRFWLVATTGGEEAAYRPQGRHGHRF 125 P+ WYS+PAL K WLD VL GWA+G GG AL GK V +TGG AY P+G HGH Sbjct: 61 PVRWYSVPALLKLWLDEVLEPGWAYGPGGTALRGKSLLAVVSTGGTADAYGPEGTHGHPI 120 Query: 126 ADFLPPYQQTAALCGMQWQEPLILHGAHHIPPEQFQRHLQHYLAGL 171 A+FL P +QTA LCGM W P++LH A++ + H+ H L Sbjct: 121 AEFLLPLEQTALLCGMTWLPPVVLHDANNADAQALADHIAHVCGRL 166 >Q8XUT8.1 Q8XUT8_RALSO Probable nad(P)h dehydrogenase (Quinone); oxidoreductase protein EC=1.6.5.2 Length = 182 Score = 174 bits (440), Expect = 6e-42, Method: Compositional matrix adjust. Identities = 89/171 (52%), Positives = 107/171 (62%) Query: 2 PKALILYAHPTAELSRTNRLLLDAAARLPEVQIHDLYEHYPDFHIDVEHEQQLLGTVELI 61 P+ L++YAHP SR N+ L A LP V +HDLY HYP+F IDV EQQ L +L+ Sbjct: 4 PRILVIYAHPAPRRSRANKPLARMLAGLPGVALHDLYWHYPEFDIDVRAEQQALEAADLV 63 Query: 62 VMQHPIHWYSMPALQKQWLDSVLTRGWAFGHGGHALHGKRFWLVATTGGEEAAYRPQGRH 121 V+Q P+ WY+ P+L K+WLD VL GWA+G GG AL GK ++ATTGG AY G H Sbjct: 64 VLQFPVQWYATPSLLKEWLDVVLEMGWAYGPGGTALRGKHMLVLATTGGRAHAYSRDGIH 123 Query: 122 GHRFADFLPPYQQTAALCGMQWQEPLILHGAHHIPPEQFQRHLQHYLAGLQ 172 GH F FL P QQTAALCGM W P +LH A PE HL+ A LQ Sbjct: 124 GHAFDLFLLPLQQTAALCGMHWLPPHVLHDADDASPEVLDAHLEQVRASLQ 174 >D8NWF8.1 D8NWF8_RALSO Glutathione-regulated potassium-efflux system ancillary protein, quinone oxidoreductase flavoprotein EC=1.10.99.2 Length = 182 Score = 171 bits (432), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 86/171 (50%), Positives = 106/171 (61%) Query: 2 PKALILYAHPTAELSRTNRLLLDAAARLPEVQIHDLYEHYPDFHIDVEHEQQLLGTVELI 61 P+ L++YAHP SR N+ L A LP V +HDLY YP+F IDV EQQ L +++ Sbjct: 4 PRILVIYAHPAQRRSRANKPLARMLAGLPGVAMHDLYWRYPEFDIDVRAEQQALEAADVV 63 Query: 62 VMQHPIHWYSMPALQKQWLDSVLTRGWAFGHGGHALHGKRFWLVATTGGEEAAYRPQGRH 121 V+Q P+ WY+ P+L K+WLD VL GWA+G GG AL GK ++AT GG AY G H Sbjct: 64 VLQFPVQWYATPSLLKEWLDVVLEMGWAYGPGGDALQGKHMLVLATAGGRAHAYSRDGVH 123 Query: 122 GHRFADFLPPYQQTAALCGMQWQEPLILHGAHHIPPEQFQRHLQHYLAGLQ 172 GH F FL P QQTAALCGM W P +LH A PE H++H A LQ Sbjct: 124 GHAFDLFLLPLQQTAALCGMHWLPPHVLHDADDASPETLDAHVEHVRATLQ 174 >B2UFD2.1 B2UFD2_RALPJ NAD(P)H dehydrogenase (Quinone) Length = 187 Score = 169 bits (429), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 88/170 (51%), Positives = 107/170 (62%) Query: 3 KALILYAHPTAELSRTNRLLLDAAARLPEVQIHDLYEHYPDFHIDVEHEQQLLGTVELIV 62 + L++YAHP SR N+ L A A LP V +HDLY HYPDF IDV EQ+ + ELIV Sbjct: 5 RILVIYAHPAPRRSRANKPLARALASLPGVAMHDLYWHYPDFDIDVRAEQEAVEAAELIV 64 Query: 63 MQHPIHWYSMPALQKQWLDSVLTRGWAFGHGGHALHGKRFWLVATTGGEEAAYRPQGRHG 122 Q P+ WY+ P+L K+W+D VL GWA+G GG AL GK ++ATTGG +Y P G HG Sbjct: 65 FQFPVQWYATPSLLKEWIDVVLEMGWAYGPGGTALRGKHLMVLATTGGRAHSYNPDGVHG 124 Query: 123 HRFADFLPPYQQTAALCGMQWQEPLILHGAHHIPPEQFQRHLQHYLAGLQ 172 H F FL P QQTAALCGMQWQ P +LH A + H+ A LQ Sbjct: 125 HTFDMFLLPLQQTAALCGMQWQPPHVLHDADDASADVIDAHIAQVRAALQ 174