BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0032.p (194 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IVL0.1 D8IVL0_HERSS 5'-methylthioadenosine nucleosidase/S-aden... 397 e-109 Q1QH75.1 Q1QH75_NITHX 5'-methylthioadenosine nucleosidase / S-ad... 223 1e-56 A3X1E7.1 A3X1E7_9BRAD 5'-methylthioadenosine nucleosidase / S-ad... 215 2e-54 D6V4Q7.1 D6V4Q7_9BRAD Purine or other phosphorylase family 1 214 4e-54 B6JJP5.1 B6JJP5_OLICO 5'-methylthioadenosine nucleosidase 214 5e-54 Q3SN26.1 Q3SN26_NITWN 5'-methylthioadenosine nucleosidase / S-ad... 206 1e-51 A4SX84.1 A4SX84_POLSQ 5'-methylthioadenosine nucleosidase / S-ad... 199 2e-49 Q4JMW1.1 Q4JMW1_9BACT Predicted 5'-methylthioadenosine/S-adenosy... 133 1e-29 Q6SF01.1 Q6SF01_9BACT 5'-methylthioadenosine/S-adenosylhomocyste... 117 7e-25 F2I1W8.1 F2I1W8_9RICK 5'-methylthioadenosine nucleosidase / S-ad... 117 9e-25 >D8IVL0.1 D8IVL0_HERSS 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase protein EC=3.2.2.9 Length = 194 Score = 397 bits (1020), Expect = e-109, Method: Compositional matrix adjust. Identities = 193/194 (99%), Positives = 194/194 (100%) Query: 1 MPDQQPILILTALESELNAAAAPADVKVVYCGVGKVNAALHTTAAILAHRPRAVINFGTA 60 MPDQQPILILTALESELNAAAAPADVKVVYCGVGKVNAALHTTAAILAHRPRAVINFGTA Sbjct: 1 MPDQQPILILTALESELNAAAAPADVKVVYCGVGKVNAALHTTAAILAHRPRAVINFGTA 60 Query: 61 GKIDPSHDGLLEVAAVIQRDMAAMPLAPRGVTPLVNQEQQPARLESGYSGVLCGTGDSFV 120 GKIDPSHDGLLEVAAVIQRDMAAMPLAPRGVTPLVNQEQQPARLESGYSGVLCGTGDSFV Sbjct: 61 GKIDPSHDGLLEVAAVIQRDMAAMPLAPRGVTPLVNQEQQPARLESGYSGVLCGTGDSFV 120 Query: 121 TAADEWLLEQKVDLVDMELFAIARVCKHFGVPWRAFKFITDGANDDAADDWQARVHLGEE 180 TAADEWLLEQKVDLVDMELFAIARVCKHFGVPWRAFKFITDGANDDAADDWQARVHLGEE Sbjct: 121 TAADEWLLEQKVDLVDMELFAIARVCKHFGVPWRAFKFITDGANDDAADDWQARVHLGEE 180 Query: 181 LFWRHLPHVIKPYA 194 LFWRHLPHV+KPYA Sbjct: 181 LFWRHLPHVLKPYA 194 >Q1QH75.1 Q1QH75_NITHX 5'-methylthioadenosine nucleosidase / S-adenosylhomocysteine nucleosidase Length = 186 Score = 223 bits (568), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 109/183 (59%), Positives = 136/183 (74%), Gaps = 3/183 (1%) Query: 7 ILILTALESELNAAAAPADVKVVYCGVGKVNAALHTTAAILAHRPRAVINFGTAGKIDPS 66 IL+LTA++ EL+ A AP V+V+Y GVGK+NAA TT A+L RP VIN+GTAGKI+ + Sbjct: 5 ILVLTAIDDELDKARAPDGVRVIYTGVGKINAASATTLALLTLRPTLVINYGTAGKINET 64 Query: 67 HDGLLEVAAVIQRDMAAMPLAPRGVTPLVNQEQQPARLESGYSGVLCGTGDSFVTAADEW 126 GL+EV+ V+QRDM AMPLAPRG TP + L SG +GV+CGTGDSFVTA+D W Sbjct: 65 LQGLVEVSGVVQRDMMAMPLAPRGRTPFAPELDL---LTSGQAGVVCGTGDSFVTASDPW 121 Query: 127 LLEQKVDLVDMELFAIARVCKHFGVPWRAFKFITDGANDDAADDWQARVHLGEELFWRHL 186 L+E ++D+VDMELFA+A+VC+ G+PWRAFKFITD AND A DW A V GE LFW L Sbjct: 122 LVENRIDIVDMELFAVAQVCRRNGLPWRAFKFITDDANDLAHQDWTANVRDGESLFWDAL 181 Query: 187 PHV 189 + Sbjct: 182 KRI 184 >A3X1E7.1 A3X1E7_9BRAD 5'-methylthioadenosine nucleosidase / S-adenosylhomocysteinenucleosidase Length = 186 Score = 215 bits (548), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 106/183 (57%), Positives = 133/183 (72%), Gaps = 3/183 (1%) Query: 7 ILILTALESELNAAAAPADVKVVYCGVGKVNAALHTTAAILAHRPRAVINFGTAGKIDPS 66 IL+LTA++ EL+ A AP V+V+Y GVGK+NAA TT A+L P VIN+GTAGKI+ + Sbjct: 5 ILVLTAIDDELDKARAPDGVRVIYTGVGKINAASATTLALLTLHPALVINYGTAGKINET 64 Query: 67 HDGLLEVAAVIQRDMAAMPLAPRGVTPLVNQEQQPARLESGYSGVLCGTGDSFVTAADEW 126 GL+EV++V+QRDM AMPLAPRG TP + L SG GV+CGTGDSFVT++D W Sbjct: 65 LQGLVEVSSVVQRDMMAMPLAPRGRTPFAPELD---FLTSGQGGVVCGTGDSFVTSSDPW 121 Query: 127 LLEQKVDLVDMELFAIARVCKHFGVPWRAFKFITDGANDDAADDWQARVHLGEELFWRHL 186 L+E +D+VDMELFA+A+VC+ G+PWR FKFITD AND A DW A V GE LFW L Sbjct: 122 LIENNIDIVDMELFAVAQVCRRHGLPWRGFKFITDDANDLAHQDWTANVKDGEGLFWDAL 181 Query: 187 PHV 189 + Sbjct: 182 ERI 184 >D6V4Q7.1 D6V4Q7_9BRAD Purine or other phosphorylase family 1 Length = 187 Score = 214 bits (546), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 109/183 (59%), Positives = 134/183 (73%), Gaps = 3/183 (1%) Query: 7 ILILTALESELNAAAAPADVKVVYCGVGKVNAALHTTAAILAHRPRAVINFGTAGKIDPS 66 IL+LTA++ EL+ A AP V+V+Y GVGKVNAA T A+L RPR V+N+GTAGKI Sbjct: 5 ILVLTAIDDELDKARAPEGVEVIYTGVGKVNAASAATLALLVLRPRLVVNYGTAGKIHKM 64 Query: 67 HDGLLEVAAVIQRDMAAMPLAPRGVTPLVNQEQQPARLESGYSGVLCGTGDSFVTAADEW 126 H+GL+EVA +QRDM AMPLAPRG TP + RL SG+ GV CGTGDSFVT D W Sbjct: 65 HNGLVEVAHAVQRDMMAMPLAPRGRTPF---SPEIDRLSSGHKGVTCGTGDSFVTTTDPW 121 Query: 127 LLEQKVDLVDMELFAIARVCKHFGVPWRAFKFITDGANDDAADDWQARVHLGEELFWRHL 186 L+E K+D+VDMEL+AIA VC+ +PWRAFKFITD A+D+AAD WQ V GE+LFW + Sbjct: 122 LVENKIDIVDMELYAIAHVCQRHSLPWRAFKFITDEADDNAADHWQDNVKDGEDLFWDAM 181 Query: 187 PHV 189 + Sbjct: 182 KEI 184 >B6JJP5.1 B6JJP5_OLICO 5'-methylthioadenosine nucleosidase Length = 186 Score = 214 bits (545), Expect = 5e-54, Method: Compositional matrix adjust. Identities = 111/177 (62%), Positives = 132/177 (74%), Gaps = 3/177 (1%) Query: 7 ILILTALESELNAAAAPADVKVVYCGVGKVNAALHTTAAILAHRPRAVINFGTAGKIDPS 66 IL+LTA++ EL+ A AP V+V+Y GVGK+NAA T A+L RPR VIN+GTAGKI Sbjct: 5 ILVLTAIDDELDKARAPDGVEVIYTGVGKINAASAATLALLVLRPRLVINYGTAGKIHKM 64 Query: 67 HDGLLEVAAVIQRDMAAMPLAPRGVTPLVNQEQQPARLESGYSGVLCGTGDSFVTAADEW 126 H+GL+EVA V+QRDM AMPLAPRG TP + L SG GV+CGTGDSFVTA D W Sbjct: 65 HNGLVEVAHVVQRDMMAMPLAPRGRTPF---SPEIDHLSSGRDGVICGTGDSFVTAPDPW 121 Query: 127 LLEQKVDLVDMELFAIARVCKHFGVPWRAFKFITDGANDDAADDWQARVHLGEELFW 183 L+E KVD+VDMEL+AIA VC+ +PWRAFKFITD A+D+AAD WQ V GEE FW Sbjct: 122 LVENKVDIVDMELYAIAHVCQRHSLPWRAFKFITDEADDNAADHWQENVRDGEETFW 178 >Q3SN26.1 Q3SN26_NITWN 5'-methylthioadenosine nucleosidase / S-adenosylhomocysteine nucleosidase EC=3.2.2.16 Length = 184 Score = 206 bits (524), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 108/183 (59%), Positives = 131/183 (71%), Gaps = 3/183 (1%) Query: 7 ILILTALESELNAAAAPADVKVVYCGVGKVNAALHTTAAILAHRPRAVINFGTAGKIDPS 66 IL+LTA+E EL A P V+V+Y GVGK+NAA T A+L P VIN+GTAGKI+ + Sbjct: 4 ILVLTAIEDELGRARLPDGVRVIYTGVGKINAASAATLALLTLHPDLVINYGTAGKINET 63 Query: 67 HDGLLEVAAVIQRDMAAMPLAPRGVTPLVNQEQQPARLESGYSGVLCGTGDSFVTAADEW 126 GL+EV+ V+QRDM AMPLAPRG TP + L SG SGV+CGTGDSFVT++D W Sbjct: 64 LRGLVEVSTVVQRDMMAMPLAPRGRTPFAPELDL---LTSGQSGVVCGTGDSFVTSSDPW 120 Query: 127 LLEQKVDLVDMELFAIARVCKHFGVPWRAFKFITDGANDDAADDWQARVHLGEELFWRHL 186 L+E VD+VDMELFA+A+VC+ G+PWRAFKFITD AND A DW A V GE LFW L Sbjct: 121 LIENNVDIVDMELFAVAQVCRRHGLPWRAFKFITDDANDLAHQDWTANVKDGEGLFWDTL 180 Query: 187 PHV 189 + Sbjct: 181 DRI 183 >A4SX84.1 A4SX84_POLSQ 5'-methylthioadenosine nucleosidase / S-adenosylhomocysteine nucleosidase Length = 185 Score = 199 bits (505), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 94/184 (51%), Positives = 129/184 (70%), Gaps = 4/184 (2%) Query: 7 ILILTALESELNAAAAPADVKVVYCGVGKVNAALHTTAAILAHRPRAVINFGTAGKIDPS 66 +LI+TALE+EL A P+ V++VY GVGK+NA + + AI H+P +INFGTAGKI+ Sbjct: 5 LLIITALETELKRDALPSGVRLVYSGVGKINATIASVKAIHEHKPARIINFGTAGKINTQ 64 Query: 67 HDGLLEVAAVIQRDMAAMPLAPRGVTPLVNQEQQPARLESGYSGVLCGTGDSFVTAADEW 126 +GLLE+ VIQRDM PLAPRG TP N+ + + SG +CG+GDSFVT D W Sbjct: 65 VNGLLEIGKVIQRDMITEPLAPRGQTPFCNRPSE--YISSGQ--FVCGSGDSFVTTTDPW 120 Query: 127 LLEQKVDLVDMELFAIARVCKHFGVPWRAFKFITDGANDDAADDWQARVHLGEELFWRHL 186 L + VD+VDMELFAIA V + +PW+++K+ITD AN+++ +DWQ R H G+ELF + L Sbjct: 121 LFSKGVDVVDMELFAIAFVASNHDIPWQSYKYITDDANENSGNDWQERAHHGQELFLQEL 180 Query: 187 PHVI 190 ++ Sbjct: 181 KQLL 184 >Q4JMW1.1 Q4JMW1_9BACT Predicted 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Length = 184 Score = 133 bits (335), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 73/185 (39%), Positives = 107/185 (57%), Gaps = 10/185 (5%) Query: 7 ILILTALESELNAAAAPADVKVVYCGVGKVNAALHTTAAILAHRPRAVINFGTAGKIDPS 66 I+IL AL+ EL+ P ++ V Y G+GK+NA T I P +IN+GTAG + Sbjct: 2 IVILVALKDELSEKDLP-NIPVHYTGLGKINATSKTLEIINDCSPSLIINYGTAGSLTRG 60 Query: 67 HDGLLEVAAVIQRDMAAMPLAPR-GVTPLVNQEQQPARLESGYSGVLCGTGDSFVTAADE 125 GL+EV QRDM A PL + G TP + + G SG CGTGDSFVT + Sbjct: 61 LKGLVEVTKFCQRDMDASPLGFKIGETPF----DEVGEINFGSSGYSCGTGDSFVTQTPK 116 Query: 126 WLLEQKVDLVDMELFAIARVCKHFGVPWRAFKFITDGANDDAADDWQARVHLGEELFWRH 185 K DLVDME +AIA++C G+ ++ FK+++D A+ A+DDW + G++LF + Sbjct: 117 L----KTDLVDMEAYAIAKICYLKGIKFKCFKYVSDNADAGASDDWAENISAGKKLFIKQ 172 Query: 186 LPHVI 190 + +++ Sbjct: 173 IRNLL 177 >Q6SF01.1 Q6SF01_9BACT 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, putative Length = 184 Score = 117 bits (294), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 72/176 (40%), Positives = 97/176 (55%), Gaps = 10/176 (5%) Query: 8 LILTALESELNAAAAPADVKVVYCGVGKVNAALHTTAAILAHRPRAVINFGTAGKIDPSH 67 +IL ALE EL + P + Y GVGK+NA+L T I P +IN+GTAG + + Sbjct: 7 IILVALEEELPKSTLPG-FHIEYTGVGKINASLKTAEVIQKFSPELIINYGTAGGLAKNL 65 Query: 68 DGLLEVAAVIQRDMAAMPLA-PRGVTPLVNQEQQPARLESGYSGVLCGTGDSFVTAADEW 126 GL+EV+ +QRDM A L G TP + G +G CGTGDSFVT Sbjct: 66 HGLVEVSHFLQRDMDARALGFSLGQTPF----DPVLTISFGRTGHSCGTGDSFVTQTPGV 121 Query: 127 LLEQKVDLVDMELFAIARVCKHFGVPWRAFKFITDGANDDAADDWQARVHLGEELF 182 + D+VDME +AIA+ C + + +KFI+DGAN +A+ DW V+ G LF Sbjct: 122 ----ETDVVDMEAYAIAKACFLKRIDFVCYKFISDGANAEASLDWTENVNKGRRLF 173 >F2I1W8.1 F2I1W8_9RICK 5'-methylthioadenosine nucleosidase / S-adenosylhomocysteine nucleosidase EC=3.2.2.16 EC=3.2.2.9 Length = 178 Score = 117 bits (293), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 60/155 (38%), Positives = 87/155 (56%), Gaps = 10/155 (6%) Query: 30 YCGVGKVNAALHTTAAILAHRPRAVINFGTAGKIDPSHDGLLEVAAVIQRDMAAMPLA-- 87 + GVGK+NA T IL H+P ++NFG+ G ++ GL+EV QRDM L Sbjct: 21 FTGVGKINATHAITQLILKHKPEEIVNFGSVGSLNKEIKGLIEVTKFYQRDMDVRGLMNL 80 Query: 88 PRGVTPLVNQEQQPARLESGYSGVLCGTGDSFVTAADEWLLEQKVDLVDMELFAIARVCK 147 G TP + + +G CGTGDSFV +E VD+VDME +A+A++CK Sbjct: 81 KLGETPF----DSIHEIITNDAGCSCGTGDSFVQGK----IEMNVDVVDMEAYALAKICK 132 Query: 148 HFGVPWRAFKFITDGANDDAADDWQARVHLGEELF 182 V ++ FKFI+D A+++A++DW G +LF Sbjct: 133 LHNVRFKCFKFISDNADENASNDWLENCKKGSQLF 167