BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0029.p (189 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IVK8.1 D8IVK8_HERSS Oxidoreductase protein 384 e-105 A1TSG9.1 A1TSG9_ACIAC Short-chain dehydrogenase/reductase SDR 346 8e-94 Q1BMA2.1 Q1BMA2_BURCA Short-chain dehydrogenase/reductase SDR 288 3e-76 A0AZA8.1 A0AZA8_BURCH Short-chain dehydrogenase/reductase SDR 288 3e-76 A4W5I8.1 A4W5I8_ENT38 Short-chain dehydrogenase/reductase SDR 283 1e-74 A1BAU6.1 A1BAU6_PARDP Short-chain dehydrogenase/reductase SDR 276 1e-72 A9AQF0.1 A9AQF0_BURM1 Short-chain dehydrogenase/reductase SDR 274 5e-72 B1K2N3.1 B1K2N3_BURCC Short-chain dehydrogenase/reductase SDR 273 6e-72 A2VZK9.1 A2VZK9_9BURK Dehydrogenase 273 7e-72 B1FD23.1 B1FD23_9BURK Short-chain dehydrogenase/reductase SDR 273 8e-72 >D8IVK8.1 D8IVK8_HERSS Oxidoreductase protein Length = 260 Score = 384 bits (987), Expect = e-105, Method: Compositional matrix adjust. Identities = 189/189 (100%), Positives = 189/189 (100%) Query: 1 LKDWGGVDILINALGGSKTPGGGFAAISDEHWFAEFNLNLMPAVRMDRALLPNMLAQGSG 60 LKDWGGVDILINALGGSKTPGGGFAAISDEHWFAEFNLNLMPAVRMDRALLPNMLAQGSG Sbjct: 72 LKDWGGVDILINALGGSKTPGGGFAAISDEHWFAEFNLNLMPAVRMDRALLPNMLAQGSG 131 Query: 61 VIIHVSSIQRVLPLPESTTAYAAAKAALTTYSKSLAREVTSKGVRVLSVAPGWIETEASV 120 VIIHVSSIQRVLPLPESTTAYAAAKAALTTYSKSLAREVTSKGVRVLSVAPGWIETEASV Sbjct: 132 VIIHVSSIQRVLPLPESTTAYAAAKAALTTYSKSLAREVTSKGVRVLSVAPGWIETEASV 191 Query: 121 AFTQRTAAHAGTDYEGGKKIIMDWLGGIPVGRPAKPQEVADLIAFLASPRSASITGTEYR 180 AFTQRTAAHAGTDYEGGKKIIMDWLGGIPVGRPAKPQEVADLIAFLASPRSASITGTEYR Sbjct: 192 AFTQRTAAHAGTDYEGGKKIIMDWLGGIPVGRPAKPQEVADLIAFLASPRSASITGTEYR 251 Query: 181 IDGGTVPTV 189 IDGGTVPTV Sbjct: 252 IDGGTVPTV 260 >A1TSG9.1 A1TSG9_ACIAC Short-chain dehydrogenase/reductase SDR Length = 260 Score = 346 bits (888), Expect = 8e-94, Method: Compositional matrix adjust. Identities = 167/189 (88%), Positives = 177/189 (93%) Query: 1 LKDWGGVDILINALGGSKTPGGGFAAISDEHWFAEFNLNLMPAVRMDRALLPNMLAQGSG 60 L++WGG+DIL+N LGGSKTPGGGFAAISDEHWFAE NLNLMPAVR+DRALLP MLAQGSG Sbjct: 72 LQNWGGIDILVNVLGGSKTPGGGFAAISDEHWFAEMNLNLMPAVRLDRALLPAMLAQGSG 131 Query: 61 VIIHVSSIQRVLPLPESTTAYAAAKAALTTYSKSLAREVTSKGVRVLSVAPGWIETEASV 120 V+IHVSSIQRVLPLPESTTAYAAAK ALTTYSKSLAREVT KGVRVLSVAPGWIETEASV Sbjct: 132 VVIHVSSIQRVLPLPESTTAYAAAKGALTTYSKSLAREVTPKGVRVLSVAPGWIETEASV 191 Query: 121 AFTQRTAAHAGTDYEGGKKIIMDWLGGIPVGRPAKPQEVADLIAFLASPRSASITGTEYR 180 AF +R AA AGTDYEGGKKI+MDWLGGIPVGRPA P EVADLIAFLASPR+ASI G EYR Sbjct: 192 AFAERMAADAGTDYEGGKKIVMDWLGGIPVGRPATPHEVADLIAFLASPRAASIAGAEYR 251 Query: 181 IDGGTVPTV 189 IDGGTVPT+ Sbjct: 252 IDGGTVPTL 260 >Q1BMA2.1 Q1BMA2_BURCA Short-chain dehydrogenase/reductase SDR Length = 259 Score = 288 bits (736), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 134/188 (71%), Positives = 166/188 (88%) Query: 1 LKDWGGVDILINALGGSKTPGGGFAAISDEHWFAEFNLNLMPAVRMDRALLPNMLAQGSG 60 + ++GGVD++++ +GGS++P GGFAA+S++ W E NLNL+PAVR+DRALLP MLAQ +G Sbjct: 71 MANFGGVDVIVHVVGGSRSPAGGFAALSEDAWQDELNLNLLPAVRLDRALLPGMLAQRAG 130 Query: 61 VIIHVSSIQRVLPLPESTTAYAAAKAALTTYSKSLAREVTSKGVRVLSVAPGWIETEASV 120 V+IHV+SIQR LPLPESTTAYAAAKA L+TYSKSL++EV+ KG+RV+ VAPGWIETEA+V Sbjct: 131 VVIHVTSIQRALPLPESTTAYAAAKAGLSTYSKSLSKEVSPKGIRVIRVAPGWIETEAAV 190 Query: 121 AFTQRTAAHAGTDYEGGKKIIMDWLGGIPVGRPAKPQEVADLIAFLASPRSASITGTEYR 180 AF +R A AGTDYEGGK+IIMD LGGIP+GRP+ P EVA+LIAFLASPR+ASITG EY Sbjct: 191 AFAERLAEQAGTDYEGGKQIIMDSLGGIPLGRPSTPGEVANLIAFLASPRAASITGAEYV 250 Query: 181 IDGGTVPT 188 IDGGT+PT Sbjct: 251 IDGGTIPT 258 >A0AZA8.1 A0AZA8_BURCH Short-chain dehydrogenase/reductase SDR Length = 259 Score = 288 bits (736), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 134/188 (71%), Positives = 166/188 (88%) Query: 1 LKDWGGVDILINALGGSKTPGGGFAAISDEHWFAEFNLNLMPAVRMDRALLPNMLAQGSG 60 + ++GGVD++++ +GGS++P GGFAA+S++ W E NLNL+PAVR+DRALLP MLAQ +G Sbjct: 71 MANFGGVDVIVHVVGGSRSPAGGFAALSEDAWQDELNLNLLPAVRLDRALLPGMLAQRAG 130 Query: 61 VIIHVSSIQRVLPLPESTTAYAAAKAALTTYSKSLAREVTSKGVRVLSVAPGWIETEASV 120 V+IHV+SIQR LPLPESTTAYAAAKA L+TYSKSL++EV+ KG+RV+ VAPGWIETEA+V Sbjct: 131 VVIHVTSIQRALPLPESTTAYAAAKAGLSTYSKSLSKEVSPKGIRVIRVAPGWIETEAAV 190 Query: 121 AFTQRTAAHAGTDYEGGKKIIMDWLGGIPVGRPAKPQEVADLIAFLASPRSASITGTEYR 180 AF +R A AGTDYEGGK+IIMD LGGIP+GRP+ P EVA+LIAFLASPR+ASITG EY Sbjct: 191 AFAERLAEQAGTDYEGGKQIIMDSLGGIPLGRPSTPGEVANLIAFLASPRAASITGAEYV 250 Query: 181 IDGGTVPT 188 IDGGT+PT Sbjct: 251 IDGGTIPT 258 >A4W5I8.1 A4W5I8_ENT38 Short-chain dehydrogenase/reductase SDR Length = 259 Score = 283 bits (723), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 135/188 (71%), Positives = 162/188 (86%) Query: 2 KDWGGVDILINALGGSKTPGGGFAAISDEHWFAEFNLNLMPAVRMDRALLPNMLAQGSGV 61 + +GGVDI+++ +GGS PGGGFAA+ +E W E NLNL+PAVR+DRALLP MLAQG+G Sbjct: 72 RHFGGVDIVVHVVGGSTAPGGGFAALGEEEWQHELNLNLLPAVRLDRALLPGMLAQGAGA 131 Query: 62 IIHVSSIQRVLPLPESTTAYAAAKAALTTYSKSLAREVTSKGVRVLSVAPGWIETEASVA 121 IIHV+SIQR LPLP+STT YAAAKAAL+TYSKSL++EV+ +GVRV+ VAPGWIETEASVA Sbjct: 132 IIHVTSIQRELPLPQSTTGYAAAKAALSTYSKSLSKEVSPQGVRVVRVAPGWIETEASVA 191 Query: 122 FTQRTAAHAGTDYEGGKKIIMDWLGGIPVGRPAKPQEVADLIAFLASPRSASITGTEYRI 181 +R A AGTDYEGGKKIIMD LGGIP+GRP+ P EVA+LI FLAS ++++ITGTEY I Sbjct: 192 LAERLALQAGTDYEGGKKIIMDSLGGIPLGRPSTPLEVANLIVFLASSQASAITGTEYVI 251 Query: 182 DGGTVPTV 189 DGGTVPTV Sbjct: 252 DGGTVPTV 259 >A1BAU6.1 A1BAU6_PARDP Short-chain dehydrogenase/reductase SDR Length = 259 Score = 276 bits (705), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 132/184 (71%), Positives = 158/184 (85%) Query: 5 GGVDILINALGGSKTPGGGFAAISDEHWFAEFNLNLMPAVRMDRALLPNMLAQGSGVIIH 64 GGVDI+++ LGGS PGGGFAA++DE W E +LNL+ AVR+DRAL+P M+AQG+GV+IH Sbjct: 75 GGVDIIVHVLGGSSAPGGGFAALTDEEWQKELDLNLLSAVRLDRALVPGMVAQGAGVVIH 134 Query: 65 VSSIQRVLPLPESTTAYAAAKAALTTYSKSLAREVTSKGVRVLSVAPGWIETEASVAFTQ 124 V+SIQR++PLP STT YAAAKAAL+TYSKSLA+EV+ +GVRVL VAPGWIETEA+ + Sbjct: 135 VTSIQRLMPLPGSTTGYAAAKAALSTYSKSLAKEVSPQGVRVLRVAPGWIETEAAARHAE 194 Query: 125 RTAAHAGTDYEGGKKIIMDWLGGIPVGRPAKPQEVADLIAFLASPRSASITGTEYRIDGG 184 R A AGTDY GGK+IIM+ LGGIP+GRPAKP E+A LIAFLAS R+ASITGTEY IDGG Sbjct: 195 RLAQEAGTDYAGGKRIIMEALGGIPLGRPAKPAEIASLIAFLASDRAASITGTEYVIDGG 254 Query: 185 TVPT 188 TVPT Sbjct: 255 TVPT 258 >A9AQF0.1 A9AQF0_BURM1 Short-chain dehydrogenase/reductase SDR Length = 259 Score = 274 bits (700), Expect = 5e-72, Method: Compositional matrix adjust. Identities = 136/188 (72%), Positives = 163/188 (86%) Query: 1 LKDWGGVDILINALGGSKTPGGGFAAISDEHWFAEFNLNLMPAVRMDRALLPNMLAQGSG 60 L GG+DI++N LGGS P GGFAA+SD+ W E +LNLMPAVR+DRALLP+MLAQGSG Sbjct: 71 LTRLGGIDIVVNVLGGSSAPAGGFAALSDDEWEKELSLNLMPAVRLDRALLPSMLAQGSG 130 Query: 61 VIIHVSSIQRVLPLPESTTAYAAAKAALTTYSKSLAREVTSKGVRVLSVAPGWIETEASV 120 VI+HV+SIQ VLPLPESTTAYAAAKAAL+TYSK+L++EVT KGVRV+ V+PGW+ETEA+V Sbjct: 131 VIVHVTSIQHVLPLPESTTAYAAAKAALSTYSKALSKEVTPKGVRVVRVSPGWVETEAAV 190 Query: 121 AFTQRTAAHAGTDYEGGKKIIMDWLGGIPVGRPAKPQEVADLIAFLASPRSASITGTEYR 180 +R AA AGTDYEGGK+IIM LGGIP+GRPA P+EVADL+ F+ASPR+ S+TGTE+ Sbjct: 191 RLAERLAAEAGTDYEGGKQIIMKALGGIPLGRPAAPREVADLVVFVASPRAGSVTGTEFV 250 Query: 181 IDGGTVPT 188 IDGGTVPT Sbjct: 251 IDGGTVPT 258 >B1K2N3.1 B1K2N3_BURCC Short-chain dehydrogenase/reductase SDR Length = 259 Score = 273 bits (699), Expect = 6e-72, Method: Compositional matrix adjust. Identities = 135/188 (71%), Positives = 167/188 (88%) Query: 1 LKDWGGVDILINALGGSKTPGGGFAAISDEHWFAEFNLNLMPAVRMDRALLPNMLAQGSG 60 + ++GGVD++++ +GGS++P GGFAA+S++ W E NLNL+PAVR+DRALLP MLAQ +G Sbjct: 71 MANFGGVDVIVHVVGGSRSPAGGFAALSEDAWQDELNLNLLPAVRLDRALLPGMLAQRAG 130 Query: 61 VIIHVSSIQRVLPLPESTTAYAAAKAALTTYSKSLAREVTSKGVRVLSVAPGWIETEASV 120 V+IHV+SIQ LPLPESTTAYAAAKAAL+TYSKSL++EV+ KG+RV+ VAPGWIETEA+V Sbjct: 131 VVIHVTSIQHALPLPESTTAYAAAKAALSTYSKSLSKEVSPKGIRVIRVAPGWIETEAAV 190 Query: 121 AFTQRTAAHAGTDYEGGKKIIMDWLGGIPVGRPAKPQEVADLIAFLASPRSASITGTEYR 180 AF +R AA AGTDYEGGK+IIMD LGGIP+GRP+ P EVA+LIAFLASPR+ASITG EY Sbjct: 191 AFAERLAAQAGTDYEGGKQIIMDSLGGIPLGRPSTPGEVANLIAFLASPRAASITGVEYV 250 Query: 181 IDGGTVPT 188 IDGGT+PT Sbjct: 251 IDGGTIPT 258 >A2VZK9.1 A2VZK9_9BURK Dehydrogenase Length = 259 Score = 273 bits (699), Expect = 7e-72, Method: Compositional matrix adjust. Identities = 135/186 (72%), Positives = 166/186 (89%) Query: 3 DWGGVDILINALGGSKTPGGGFAAISDEHWFAEFNLNLMPAVRMDRALLPNMLAQGSGVI 62 ++GGVD++++ +GGS++P GGFAA+S++ W E NLNL+PAVR+DRALLP MLA +GV+ Sbjct: 73 NFGGVDVIVHVVGGSRSPAGGFAALSEDAWHDELNLNLLPAVRLDRALLPGMLAHRAGVV 132 Query: 63 IHVSSIQRVLPLPESTTAYAAAKAALTTYSKSLAREVTSKGVRVLSVAPGWIETEASVAF 122 IHV+SIQR LPLPESTTAYAAAKAAL+TYSKSL++EV+ KG+RV+ VAPGWIETEA+VAF Sbjct: 133 IHVTSIQRALPLPESTTAYAAAKAALSTYSKSLSKEVSPKGIRVIRVAPGWIETEAAVAF 192 Query: 123 TQRTAAHAGTDYEGGKKIIMDWLGGIPVGRPAKPQEVADLIAFLASPRSASITGTEYRID 182 +R AA AGTDYEGGK+IIMD LGGIP+GRP+ P EVA+LIAFLASPR+ASITG EY ID Sbjct: 193 AERLAAQAGTDYEGGKQIIMDSLGGIPLGRPSTPGEVANLIAFLASPRAASITGVEYVID 252 Query: 183 GGTVPT 188 GGT+PT Sbjct: 253 GGTIPT 258 >B1FD23.1 B1FD23_9BURK Short-chain dehydrogenase/reductase SDR Length = 259 Score = 273 bits (698), Expect = 8e-72, Method: Compositional matrix adjust. Identities = 137/185 (74%), Positives = 165/185 (89%) Query: 4 WGGVDILINALGGSKTPGGGFAAISDEHWFAEFNLNLMPAVRMDRALLPNMLAQGSGVII 63 +GGVDI+++ +GGS PGGGFAA ++ W+ E NLNL+PAVR+DRALLP MLAQG+GV+I Sbjct: 74 FGGVDIIVHVVGGSTAPGGGFAASGEDEWWQELNLNLLPAVRLDRALLPGMLAQGAGVVI 133 Query: 64 HVSSIQRVLPLPESTTAYAAAKAALTTYSKSLAREVTSKGVRVLSVAPGWIETEASVAFT 123 HV+SIQR LPLPESTTAYAAAKAAL+TYSKSL++EV+ KG+RV+ VAPGW+ETEASVA Sbjct: 134 HVTSIQRELPLPESTTAYAAAKAALSTYSKSLSKEVSPKGIRVVRVAPGWVETEASVALA 193 Query: 124 QRTAAHAGTDYEGGKKIIMDWLGGIPVGRPAKPQEVADLIAFLASPRSASITGTEYRIDG 183 +R A AGTDYEGGKKIIM+ LGGIPVGRP++P EVA+LIAFLASPR+A+ITGTEY IDG Sbjct: 194 ERLALQAGTDYEGGKKIIMNSLGGIPVGRPSQPIEVANLIAFLASPRAATITGTEYVIDG 253 Query: 184 GTVPT 188 GT+PT Sbjct: 254 GTIPT 258