BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0026.p (229 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IVK4.1 D8IVK4_HERSS Multiple antibiotic resistance protein 456 e-126 A6SZ91.1 A6SZ91_JANMA Multiple antibiotic resistance protein MarC 322 2e-86 A4G533.1 A4G533_HERAR Putative multiple antibiotic resistance pr... 320 9e-86 Q7WJ97.1 Q7WJ97_BORBR Putative multiple antibiotic resistance pr... 184 8e-45 Q7NUG9.1 Q7NUG9_CHRVO Probable multiple antibiotic resistance pr... 181 7e-44 Q7WA63.1 Q7WA63_BORPA Putative multiple antibiotic resistance pr... 180 1e-43 E8UDD3.1 E8UDD3_TAYEM Putative multiple antibiotic resistance pr... 179 2e-43 C1D7D3.1 C1D7D3_LARHH Probable multiple antibiotic resistance pr... 174 7e-42 E3HTK2.1 E3HTK2_ACHXA MarC family integral membrane family prote... 174 1e-41 E5U3G8.1 E5U3G8_ALCXX Multiple antibiotic resistance protein 173 2e-41 >D8IVK4.1 D8IVK4_HERSS Multiple antibiotic resistance protein Length = 229 Score = 456 bits (1172), Expect = e-126, Method: Compositional matrix adjust. Identities = 229/229 (100%), Positives = 229/229 (100%) Query: 1 MFILFLKAVVLIPVTLLPILNPLGIAPVFANLLGNVSRSTEKRIARQVAINCWFMLVAAI 60 MFILFLKAVVLIPVTLLPILNPLGIAPVFANLLGNVSRSTEKRIARQVAINCWFMLVAAI Sbjct: 1 MFILFLKAVVLIPVTLLPILNPLGIAPVFANLLGNVSRSTEKRIARQVAINCWFMLVAAI 60 Query: 61 FIGSHVLTFFGISLPIVRVGGGLLVAVSGWKLLNDNSQDSSIPTQVAKTYDEDLPDDEIK 120 FIGSHVLTFFGISLPIVRVGGGLLVAVSGWKLLNDNSQDSSIPTQVAKTYDEDLPDDEIK Sbjct: 61 FIGSHVLTFFGISLPIVRVGGGLLVAVSGWKLLNDNSQDSSIPTQVAKTYDEDLPDDEIK 120 Query: 121 ARSFYPMSFPLTVGPGTIAASITLGANTPTRLLDWVISVGSAALGAALTALVIFLCYNYA 180 ARSFYPMSFPLTVGPGTIAASITLGANTPTRLLDWVISVGSAALGAALTALVIFLCYNYA Sbjct: 121 ARSFYPMSFPLTVGPGTIAASITLGANTPTRLLDWVISVGSAALGAALTALVIFLCYNYA 180 Query: 181 HKLVHLMGRLGTMVVLRLSAFILLCIGIQIFWSGMSALLAEAGISGVAP 229 HKLVHLMGRLGTMVVLRLSAFILLCIGIQIFWSGMSALLAEAGISGVAP Sbjct: 181 HKLVHLMGRLGTMVVLRLSAFILLCIGIQIFWSGMSALLAEAGISGVAP 229 >A6SZ91.1 A6SZ91_JANMA Multiple antibiotic resistance protein MarC Length = 226 Score = 322 bits (826), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 157/225 (69%), Positives = 192/225 (85%), Gaps = 1/225 (0%) Query: 1 MFILFLKAVVLIPVTLLPILNPLGIAPVFANLLGNVSRSTEKRIARQVAINCWFMLVAAI 60 M ILF KA +L+P+T+LPI+NP G APVFA+LLGNVSR EK++ARQVA+NC+F+L+ A+ Sbjct: 1 MLILFFKAAILVPITMLPIINPFGNAPVFASLLGNVSRDVEKKLARQVALNCFFLLLGAM 60 Query: 61 FIGSHVLTFFGISLPIVRVGGGLLVAVSGWKLLNDNSQDSSIPTQVAKTYDEDLPDDEIK 120 FIGSHVL FFGIS+PIVR+ GGLLVA + W+LLNDN QD+ I TQVA E D+E K Sbjct: 61 FIGSHVLMFFGISIPIVRISGGLLVAFTAWRLLNDNGQDA-IRTQVATAPMEAWSDEEFK 119 Query: 121 ARSFYPMSFPLTVGPGTIAASITLGANTPTRLLDWVISVGSAALGAALTALVIFLCYNYA 180 RSFYP+SFPLTVGPG IAASITLGA+TP RLLD VIS+GSAA+GAA+TA VI+LCYN A Sbjct: 120 VRSFYPISFPLTVGPGAIAASITLGASTPARLLDQVISLGSAAVGAAMTAFVIWLCYNSA 179 Query: 181 HKLVHLMGRLGTMVVLRLSAFILLCIGIQIFWSGMSALLAEAGIS 225 +K+V ++GRLGTMV+LRLSAFILLCIG++IFW+G+ LL EAGI+ Sbjct: 180 NKMVKMLGRLGTMVMLRLSAFILLCIGVEIFWTGVVGLLVEAGIA 224 >A4G533.1 A4G533_HERAR Putative multiple antibiotic resistance protein MarC Length = 226 Score = 320 bits (820), Expect = 9e-86, Method: Compositional matrix adjust. Identities = 158/225 (70%), Positives = 187/225 (83%), Gaps = 1/225 (0%) Query: 1 MFILFLKAVVLIPVTLLPILNPLGIAPVFANLLGNVSRSTEKRIARQVAINCWFMLVAAI 60 M ILF KA +LIP+TL+PILNP G A +FA+L G++ R EKR+ARQVAINC+ ML+ + Sbjct: 1 MLILFFKAAILIPITLVPILNPFGNAAIFASLAGDIDRDAEKRLARQVAINCFVMLLGTM 60 Query: 61 FIGSHVLTFFGISLPIVRVGGGLLVAVSGWKLLNDNSQDSSIPTQVAKTYDEDLPDDEIK 120 FIGSHVL FFGISLPIVR+GGG+LVA +GW+LLND QD I TQVA E +D+ K Sbjct: 61 FIGSHVLMFFGISLPIVRIGGGILVAATGWRLLNDKGQDD-IRTQVASKPREVWSEDDFK 119 Query: 121 ARSFYPMSFPLTVGPGTIAASITLGANTPTRLLDWVISVGSAALGAALTALVIFLCYNYA 180 RSFYP+SFPLTVGPGTIAASITLGA+ P+RL + +S+GSAALGAA+TALVIFLCY YA Sbjct: 120 VRSFYPISFPLTVGPGTIAASITLGASAPSRLSNLFVSIGSAALGAAMTALVIFLCYRYA 179 Query: 181 HKLVHLMGRLGTMVVLRLSAFILLCIGIQIFWSGMSALLAEAGIS 225 +K+V L+GRLGTMVVLRLSAFILLCIGI+IFW GM LLAEAGI+ Sbjct: 180 NKMVRLLGRLGTMVVLRLSAFILLCIGIEIFWQGMLGLLAEAGIT 224 >Q7WJ97.1 Q7WJ97_BORBR Putative multiple antibiotic resistance protein Length = 237 Score = 184 bits (467), Expect = 8e-45, Method: Compositional matrix adjust. Identities = 97/221 (43%), Positives = 144/221 (65%), Gaps = 7/221 (3%) Query: 3 ILFLKAVVLIPVTLLPILNPLGIAPVFANLLGNVSRSTEKRIARQVAINCWFMLVAAIFI 62 ++F ++ TLLP LNP I P+F L S+ T +++++VAIN M++ A+ Sbjct: 8 LVFGRSFFFALATLLPFLNPPAITPIFWTLTEGASKQTRAQLSKRVAINVALMMIGAMIA 67 Query: 63 GSHVLTFFGISLPIVRVGGGLLVAVSGWKLLNDNSQDSSIPTQVAKTYDEDLPDDEIKAR 122 G+ VL+FFGISL IVRVGGG+LV S W+L+N D+S Q+A+++ ++ +AR Sbjct: 68 GNVVLSFFGISLAIVRVGGGMLVIYSAWRLVNSPDADTSRHAQMAESFTPEM----AQAR 123 Query: 123 SFYPMSFPLTVGPGTIAASITLGAN--TPTRLLDWVISVGSAALGAALTALVIFLCYNYA 180 +FYP++FP++ GPGTIAA IT+GA+ +L GS G AL A +F+C +A Sbjct: 124 AFYPLTFPISCGPGTIAACITVGASLRDENHMLSLARLAGSLP-GVALVAFTLFICLRFA 182 Query: 181 HKLVHLMGRLGTMVVLRLSAFILLCIGIQIFWSGMSALLAE 221 +++H +G GT V +RLSAFI+LC+G+QIFWSG S LL + Sbjct: 183 AQMLHRLGDNGTAVFMRLSAFIMLCLGVQIFWSGASELLLD 223 >Q7NUG9.1 Q7NUG9_CHRVO Probable multiple antibiotic resistance protein MarC Length = 233 Score = 181 bits (459), Expect = 7e-44, Method: Compositional matrix adjust. Identities = 87/220 (39%), Positives = 143/220 (65%), Gaps = 6/220 (2%) Query: 5 FLKAVVLIPVTLLPILNPLGIAPVFANLLGNVSRSTEKRIARQVAINCWFMLVAAIFIGS 64 F+ + + LLPI+NP G+ P+F ++ + + +AR++AI C +LV ++F+G Sbjct: 7 FITKFLFVMAALLPIMNPPGLVPIFISMTARNTPQQRRYLARRIAIYCALLLVGSMFVGG 66 Query: 65 HVLTFFGISLPIVRVGGGLLVAVSGWKLLNDNSQDSSIPTQVAKTYDEDLPDDEIKARSF 124 +VL+FFG+SLP+V++ GGLL+ + W++LND +SS P+ D E+K R+F Sbjct: 67 YVLSFFGVSLPVVQMSGGLLITFAAWRMLNDTPAESSQPSAEQARVDS---QAELKQRAF 123 Query: 125 YPMSFPLTVGPGTIAASITLGAN---TPTRLLDWVISVGSAALGAALTALVIFLCYNYAH 181 YP++FPLTVGPG+++ +IT+GA + L+ +VIS + + + +++LCY A Sbjct: 124 YPLTFPLTVGPGSVSVAITIGATLTGSGKGLVRFVISPIAGLSAVLVGSTLVYLCYANAD 183 Query: 182 KLVHLMGRLGTMVVLRLSAFILLCIGIQIFWSGMSALLAE 221 KL+ +G+ G++V LRLSAFILLC+G+QI W G L ++ Sbjct: 184 KLLRYLGQTGSVVFLRLSAFILLCLGVQIMWDGFGELASQ 223 >Q7WA63.1 Q7WA63_BORPA Putative multiple antibiotic resistance protein Length = 237 Score = 180 bits (457), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 95/209 (45%), Positives = 138/209 (66%), Gaps = 7/209 (3%) Query: 15 TLLPILNPLGIAPVFANLLGNVSRSTEKRIARQVAINCWFMLVAAIFIGSHVLTFFGISL 74 TLLP LNP I P+F L S+ T +++++VAIN M++ A+ G+ VL+FFGISL Sbjct: 20 TLLPFLNPPAITPIFWTLTEGASKQTLAQLSKRVAINVALMMIGAMIAGNVVLSFFGISL 79 Query: 75 PIVRVGGGLLVAVSGWKLLNDNSQDSSIPTQVAKTYDEDLPDDEIKARSFYPMSFPLTVG 134 IVRVGGG+LV S W+L+N D+S Q+A+++ ++ +AR+FYP++FP++ G Sbjct: 80 AIVRVGGGMLVIYSAWRLVNSPDADTSRHAQMAESFTPEM----AQARAFYPLTFPISCG 135 Query: 135 PGTIAASITLGAN--TPTRLLDWVISVGSAALGAALTALVIFLCYNYAHKLVHLMGRLGT 192 PGTIAA IT+GA+ +L GS G AL A +F+C +A +++H +G GT Sbjct: 136 PGTIAACITVGASLRDENHMLSLARLAGSLP-GVALVAFTLFICLRFAAQMLHRLGDNGT 194 Query: 193 MVVLRLSAFILLCIGIQIFWSGMSALLAE 221 V +RLSAFI+LC+G+QIFWS S LL + Sbjct: 195 AVFMRLSAFIMLCLGVQIFWSDASELLLD 223 >E8UDD3.1 E8UDD3_TAYEM Putative multiple antibiotic resistance protein Length = 225 Score = 179 bits (455), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 101/224 (45%), Positives = 143/224 (63%), Gaps = 12/224 (5%) Query: 1 MFILFLKAVVLIPVTLLPILNPLGIAPVFANLLGNVSRSTEKRIARQVAINCWFMLVAAI 60 MF + L + +L+ T+LPI+NP G+AP+F +L S T K +A++VA+N F+++ A Sbjct: 1 MFSIILGSFLLVLGTILPIVNPPGVAPIFWSLTTGASNKTRKILAKRVALNAIFIVIVAT 60 Query: 61 FIGSHVLTFFGISLPIVRVGGGLLVAVSGWKLLNDNSQDSSIPTQVAKTYDEDLPDDEIK 120 F+G VL GIS+P VRV GGLLV + WKLLN D+ + A+TY D+ K Sbjct: 61 FLGKLVLFALGISIPAVRVAGGLLVIGAAWKLLNAEDPDTGMHDISAETYTL----DKAK 116 Query: 121 ARSFYPMSFPLTVGPGTIAASITLG-----ANTPTRLLDWVISVGSAALGAALTALVIFL 175 + +FYP++FP+T GPGT+AASITLG +N LL +I LGA L IF+ Sbjct: 117 SSAFYPLTFPITCGPGTVAASITLGTTFSYSNLNLELLSNII---GTVLGAMGVGLAIFI 173 Query: 176 CYNYAHKLVHLMGRLGTMVVLRLSAFILLCIGIQIFWSGMSALL 219 +A +L+H +G GT++ +RLSAFILLCIG+QIFW+GM + Sbjct: 174 SLYFAAELLHKLGNQGTVIFMRLSAFILLCIGVQIFWTGMHEFI 217 >C1D7D3.1 C1D7D3_LARHH Probable multiple antibiotic resistance protein MarC Length = 235 Score = 174 bits (442), Expect = 7e-42, Method: Compositional matrix adjust. Identities = 86/223 (38%), Positives = 145/223 (65%), Gaps = 7/223 (3%) Query: 1 MFILFLKAVVLIPVTLLPILNPLGIAPVFANLLGNVSRSTEKRIARQVAINCWFMLVAAI 60 +F F + LLPI+NP G+ P+F +L +R + +AR++AI + +L ++ Sbjct: 3 LFSFFAGKFLFALAALLPIINPPGLIPIFLSLTSRNTREQRQFLARRIAIYGFVLLAGSM 62 Query: 61 FIGSHVLTFFGISLPIVRVGGGLLVAVSGWKLLNDNSQDSSIPTQVAKTYDEDLPDDEIK 120 FIGS++L+FFG+SLP+V++GGGLL+ + W++LND + S T + E + ++K Sbjct: 63 FIGSYLLSFFGVSLPVVQLGGGLLLTFTAWRMLNDTPAEHS--THAPE--PEHIDQAQLK 118 Query: 121 ARSFYPMSFPLTVGPGTIAASITLGA---NTPTRLLDWVISVGSAALGAALTALVIFLCY 177 R+FYP+ FPLTVGPG+++ SIT+GA ++ + ++ ++ L A+ +I+ CY Sbjct: 119 QRAFYPLGFPLTVGPGSVSVSITIGATFFHSNHNFVQLALTPVASLLAVAVVCYLIYFCY 178 Query: 178 NYAHKLVHLMGRLGTMVVLRLSAFILLCIGIQIFWSGMSALLA 220 +A ++H +G G +V LRLSAFIL+C+G+QI W+G+S L++ Sbjct: 179 LHAETMLHHLGPTGAVVFLRLSAFILVCLGMQIMWNGISELIS 221 >E3HTK2.1 E3HTK2_ACHXA MarC family integral membrane family protein 2 Length = 237 Score = 174 bits (440), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 91/208 (43%), Positives = 140/208 (67%), Gaps = 9/208 (4%) Query: 15 TLLPILNPLGIAPVFANLLGNVSRSTEKRIARQVAINCWFMLVAAIFIGSHVLTFFGISL 74 TLLP LNP IAP+F +L S ST +A++VAIN ML+ A+ G+ +L+FFGISL Sbjct: 20 TLLPFLNPPAIAPIFLSLTEGASSSTRMVLAKRVAINVCLMLIVAMVAGNVLLSFFGISL 79 Query: 75 PIVRVGGGLLVAVSGWKLLNDNSQDSSIPTQVAKTYDEDLPDDEIKARSFYPMSFPLTVG 134 IVRVGGG+LV S W+L+N D+ ++A+++ ++ KAR+FYP++FP++ G Sbjct: 80 SIVRVGGGMLVIASAWRLVNSPDADTERVARMAESFTPEMA----KARAFYPLTFPISCG 135 Query: 135 PGTIAASITLGANTPTRLLDWVIS---VGSAALGAALTALVIFLCYNYAHKLVHLMGRLG 191 PG+IAA+IT+G + R + V+S +G + G + ++ +++C +A +++H +G G Sbjct: 136 PGSIAAAITVGVS--LRDQNHVLSLVRLGGSIPGIIVVSVTLYICLRFAAQMLHRLGDNG 193 Query: 192 TMVVLRLSAFILLCIGIQIFWSGMSALL 219 T V +RLSAFI+LC+G+QIFW G LL Sbjct: 194 TAVFMRLSAFIMLCLGVQIFWEGSRELL 221 >E5U3G8.1 E5U3G8_ALCXX Multiple antibiotic resistance protein Length = 237 Score = 173 bits (438), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 90/208 (43%), Positives = 139/208 (66%), Gaps = 9/208 (4%) Query: 15 TLLPILNPLGIAPVFANLLGNVSRSTEKRIARQVAINCWFMLVAAIFIGSHVLTFFGISL 74 TLLP LNP IAP+F +L S ST +A++VAIN ML+ A+ G+ +L+FFGISL Sbjct: 20 TLLPFLNPPAIAPIFLSLTEGASSSTRTVLAKRVAINVGLMLIVAMVAGNVLLSFFGISL 79 Query: 75 PIVRVGGGLLVAVSGWKLLNDNSQDSSIPTQVAKTYDEDLPDDEIKARSFYPMSFPLTVG 134 IVRVGGG+LV S W+L+N D+ ++A+++ ++ K R+FYP++FP++ G Sbjct: 80 SIVRVGGGMLVIASAWRLVNSPDADTERVARMAESFTPEMA----KTRAFYPLTFPISCG 135 Query: 135 PGTIAASITLGANTPTRLLDWVIS---VGSAALGAALTALVIFLCYNYAHKLVHLMGRLG 191 PG+IAA+IT+G + R + V+S +G + G + +L +++C +A +++H +G G Sbjct: 136 PGSIAAAITVGVS--LRDQNHVLSLLRLGGSIPGIVVVSLTLYVCLRFAAQMLHRLGDNG 193 Query: 192 TMVVLRLSAFILLCIGIQIFWSGMSALL 219 T V +R+SAFI+LC+G+QIFW G LL Sbjct: 194 TAVFMRMSAFIMLCLGVQIFWEGSRELL 221