BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0002.p (161 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IUQ3.1 D8IUQ3_HERSS Cytoplasmic L-asparaginase I protein EC=3.... 331 3e-89 B9TP42.1 B9TP42_RICCO L-asparaginase, putative EC=3.5.1.1 251 3e-65 A6T4D1.1 A6T4D1_JANMA L-asparaginase EC=3.5.1.1 245 1e-63 A4GAM6.1 A4GAM6_HERAR Putative Asparaginase/glutaminase 241 4e-62 C3XBW1.1 C3XBW1_OXAFO L-asparaginase 209 8e-53 C3X5N6.1 C3X5N6_OXAFO L-asparaginase 207 4e-52 Q0MX85.1 Q0MX85_9BACT Asparaginase 191 4e-47 Q2IJT6.1 Q2IJT6_ANADE Asparaginase 190 5e-47 C1AAW7.1 C1AAW7_GEMAT Putative asparaginase 188 2e-46 B4UME7.1 B4UME7_ANASK Asparaginase 184 4e-45 >D8IUQ3.1 D8IUQ3_HERSS Cytoplasmic L-asparaginase I protein EC=3.5.1.1 Length = 161 Score = 331 bits (848), Expect = 3e-89, Method: Compositional matrix adjust. Identities = 161/161 (100%), Positives = 161/161 (100%) Query: 1 MSLRIIATGGTFDKHYDEIAGQLGFGESHLPDVIARARITAEVSLEILPLLDSLEMQDGD 60 MSLRIIATGGTFDKHYDEIAGQLGFGESHLPDVIARARITAEVSLEILPLLDSLEMQDGD Sbjct: 1 MSLRIIATGGTFDKHYDEIAGQLGFGESHLPDVIARARITAEVSLEILPLLDSLEMQDGD 60 Query: 61 RQRVLAACQASSQQAIVIVHGTDTMQQTAQVLGQALTGKTVVLTGAMIPYEIANSDALFN 120 RQRVLAACQASSQQAIVIVHGTDTMQQTAQVLGQALTGKTVVLTGAMIPYEIANSDALFN Sbjct: 61 RQRVLAACQASSQQAIVIVHGTDTMQQTAQVLGQALTGKTVVLTGAMIPYEIANSDALFN 120 Query: 121 FGFACGVAQVLPAGVYVAMNGRIFAWNKVAKNRSAGVFEPL 161 FGFACGVAQVLPAGVYVAMNGRIFAWNKVAKNRSAGVFEPL Sbjct: 121 FGFACGVAQVLPAGVYVAMNGRIFAWNKVAKNRSAGVFEPL 161 >B9TP42.1 B9TP42_RICCO L-asparaginase, putative EC=3.5.1.1 Length = 258 Score = 251 bits (641), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 114/161 (70%), Positives = 140/161 (86%) Query: 1 MSLRIIATGGTFDKHYDEIAGQLGFGESHLPDVIARARITAEVSLEILPLLDSLEMQDGD 60 M+LRIIATGGTFDKHY+E+ G LGF ESHLP+VIAR+R+T V L+++ +LDSL+MQD D Sbjct: 98 MTLRIIATGGTFDKHYNELNGVLGFAESHLPEVIARSRMTIPVELQVVSMLDSLDMQDTD 157 Query: 61 RQRVLAACQASSQQAIVIVHGTDTMQQTAQVLGQALTGKTVVLTGAMIPYEIANSDALFN 120 RQ VLAACQA++++ IVIVHGTDTM++TA+VLG A + KT+V TGAMIPYEIANSDALFN Sbjct: 158 RQNVLAACQAATEKQIVIVHGTDTMRETAEVLGAATSDKTIVFTGAMIPYEIANSDALFN 217 Query: 121 FGFACGVAQVLPAGVYVAMNGRIFAWNKVAKNRSAGVFEPL 161 FGFAC AQ+LP GVYVAMNG++F W+ V KNR+AGVF+ L Sbjct: 218 FGFACAAAQMLPPGVYVAMNGKVFTWDNVTKNRAAGVFQAL 258 >A6T4D1.1 A6T4D1_JANMA L-asparaginase EC=3.5.1.1 Length = 161 Score = 245 bits (626), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 112/161 (69%), Positives = 130/161 (80%) Query: 1 MSLRIIATGGTFDKHYDEIAGQLGFGESHLPDVIARARITAEVSLEILPLLDSLEMQDGD 60 M+LRIIATGGTFDKHYDEI GQL F HLP VI RARIT + LE LP LDSL+M D D Sbjct: 1 MTLRIIATGGTFDKHYDEITGQLNFSHGHLPQVIKRARITVPLQLEQLPFLDSLDMHDAD 60 Query: 61 RQRVLAACQASSQQAIVIVHGTDTMQQTAQVLGQALTGKTVVLTGAMIPYEIANSDALFN 120 RQR+ A+C + + +IV+VHGTDTM++TA+VLG A KT+VLTGAMIPYE+ NSDALFN Sbjct: 61 RQRIAASCLRADETSIVVVHGTDTMRETAEVLGAAQLPKTIVLTGAMIPYEVKNSDALFN 120 Query: 121 FGFACGVAQVLPAGVYVAMNGRIFAWNKVAKNRSAGVFEPL 161 FGFACG+AQ LP GVY+AMN +IF WN V KNRSAGVFE + Sbjct: 121 FGFACGIAQALPHGVYIAMNAQIFTWNNVRKNRSAGVFEKI 161 >A4GAM6.1 A4GAM6_HERAR Putative Asparaginase/glutaminase Length = 161 Score = 241 bits (614), Expect = 4e-62, Method: Compositional matrix adjust. Identities = 107/159 (67%), Positives = 129/159 (81%) Query: 1 MSLRIIATGGTFDKHYDEIAGQLGFGESHLPDVIARARITAEVSLEILPLLDSLEMQDGD 60 M+LRIIATGGTFDKHYDEIAG+L F + HLP +I R RIT + LE LP LDSL+M D D Sbjct: 1 MTLRIIATGGTFDKHYDEIAGKLNFSKGHLPQIIKRCRITVPIQLEQLPFLDSLDMHDAD 60 Query: 61 RQRVLAACQASSQQAIVIVHGTDTMQQTAQVLGQALTGKTVVLTGAMIPYEIANSDALFN 120 RQR+ A+C + + +IV+VHGTDTM++TA+VLG A KT+VLTGAM+PYE+ NSDALFN Sbjct: 61 RQRIAASCLRADETSIVVVHGTDTMRETAEVLGAAQLPKTIVLTGAMVPYEVKNSDALFN 120 Query: 121 FGFACGVAQVLPAGVYVAMNGRIFAWNKVAKNRSAGVFE 159 FGFACG+AQ LP GVY+AMN +IF WN V KNR+ GVFE Sbjct: 121 FGFACGIAQALPHGVYIAMNAQIFTWNDVKKNRAEGVFE 159 >C3XBW1.1 C3XBW1_OXAFO L-asparaginase Length = 162 Score = 209 bits (533), Expect = 8e-53, Method: Compositional matrix adjust. Identities = 96/159 (60%), Positives = 117/159 (73%) Query: 1 MSLRIIATGGTFDKHYDEIAGQLGFGESHLPDVIARARITAEVSLEILPLLDSLEMQDGD 60 M+L IIATGGTF+KHYDEI G+L F SH+P ++ RAR++ + + L +LDSL+MQD D Sbjct: 1 MNLHIIATGGTFEKHYDEITGELVFTSSHIPAMMERARVSQSYTFQELTMLDSLDMQDAD 60 Query: 61 RQRVLAACQASSQQAIVIVHGTDTMQQTAQVLGQALTGKTVVLTGAMIPYEIANSDALFN 120 R+ +L +C+ IVIVHGTDTMQ TA VLG+A KT+VLTGAMIPYE SDA FN Sbjct: 61 RENILKSCREIPADRIVIVHGTDTMQDTAAVLGKAALEKTIVLTGAMIPYEFDRSDAFFN 120 Query: 121 FGFACGVAQVLPAGVYVAMNGRIFAWNKVAKNRSAGVFE 159 GFA Q+LP GVY+ MNG+IF WNKV KNR GVFE Sbjct: 121 LGFAVSAVQLLPTGVYILMNGQIFKWNKVTKNRPIGVFE 159 >C3X5N6.1 C3X5N6_OXAFO L-asparaginase Length = 164 Score = 207 bits (527), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 96/159 (60%), Positives = 121/159 (76%) Query: 1 MSLRIIATGGTFDKHYDEIAGQLGFGESHLPDVIARARITAEVSLEILPLLDSLEMQDGD 60 M+L IIATGGTF+KHYDEI+G+L FGESH+P ++ RAR++ + E + +LDSL+MQ+ D Sbjct: 1 MTLHIIATGGTFEKHYDEISGRLVFGESHIPSLMKRARVSLPYTFETVCMLDSLDMQESD 60 Query: 61 RQRVLAACQASSQQAIVIVHGTDTMQQTAQVLGQALTGKTVVLTGAMIPYEIANSDALFN 120 R ++ AC S IVIVHGTDTM++TA VLG+A KT+VLTGAMIP E +SDALFN Sbjct: 61 RLKIREACAMSPAGKIVIVHGTDTMRETAAVLGKAAFQKTIVLTGAMIPCEFDHSDALFN 120 Query: 121 FGFACGVAQVLPAGVYVAMNGRIFAWNKVAKNRSAGVFE 159 GFA G Q+LP GVYV MNGR+F W +V KNR G+FE Sbjct: 121 LGFATGAVQLLPNGVYVLMNGRVFDWERVRKNRREGLFE 159 >Q0MX85.1 Q0MX85_9BACT Asparaginase Length = 161 Score = 191 bits (484), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 94/161 (58%), Positives = 117/161 (72%), Gaps = 1/161 (0%) Query: 1 MSLRIIATGGTFDKHYDEIAGQLGFGESHLPDVIARARITAEVSLEILPLLDSLEMQDGD 60 M+LRI+ATGGTFDK YD G LGFGESHLP ++ RAR+ A V +EI+ L+DSL+M D Sbjct: 1 MNLRILATGGTFDKRYDPERGTLGFGESHLPAILERARVAA-VPVEIVMLIDSLDMVDAH 59 Query: 61 RQRVLAACQASSQQAIVIVHGTDTMQQTAQVLGQALTGKTVVLTGAMIPYEIANSDALFN 120 RQRVL AC+A+ + ++V+VHGTDTM +TA VLG A KT+VLTGAM+P+ + +SDA FN Sbjct: 60 RQRVLEACRAAPESSLVVVHGTDTMVETAAVLGSAALPKTIVLTGAMVPWSVDDSDASFN 119 Query: 121 FGFACGVAQVLPAGVYVAMNGRIFAWNKVAKNRSAGVFEPL 161 G A AQ L GV+VAMNG W V KNR G+FE L Sbjct: 120 LGTAVAFAQCLDHGVWVAMNGIARPWTDVRKNRERGIFESL 160 >Q2IJT6.1 Q2IJT6_ANADE Asparaginase Length = 167 Score = 190 bits (483), Expect = 5e-47, Method: Compositional matrix adjust. Identities = 89/159 (55%), Positives = 118/159 (74%) Query: 3 LRIIATGGTFDKHYDEIAGQLGFGESHLPDVIARARITAEVSLEILPLLDSLEMQDGDRQ 62 +R+ TGGTFDK YDE++G+L F ++HLP+++ AR EVS+ L ++DSL+M DGDR+ Sbjct: 8 IRVFVTGGTFDKEYDELSGRLYFKDTHLPEMLRLARCRLEVSVRNLMMVDSLDMTDGDRR 67 Query: 63 RVLAACQASSQQAIVIVHGTDTMQQTAQVLGQALTGKTVVLTGAMIPYEIANSDALFNFG 122 ++ +C+A+++ IV+ HGTDTM +TA+ L A GKTVVLTGAMIPY +SD LFN G Sbjct: 68 IIVESCRAAAEDRIVVTHGTDTMAETARALLAAGLGKTVVLTGAMIPYAFGSSDGLFNLG 127 Query: 123 FACGVAQVLPAGVYVAMNGRIFAWNKVAKNRSAGVFEPL 161 A QVLP GVYVAMNGR+FA +KV KNR G+FE L Sbjct: 128 SALSFVQVLPPGVYVAMNGRVFAGDKVRKNRQTGIFEDL 166 >C1AAW7.1 C1AAW7_GEMAT Putative asparaginase Length = 169 Score = 188 bits (478), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 88/159 (55%), Positives = 110/159 (69%) Query: 1 MSLRIIATGGTFDKHYDEIAGQLGFGESHLPDVIARARITAEVSLEILPLLDSLEMQDGD 60 MSLR+ TGGTFDK YDE+ G L F E+HLP+++ R R +V +E+L ++DSLEM Sbjct: 1 MSLRVFVTGGTFDKEYDELTGTLRFRETHLPEMLRRGRSMLDVQVEVLMMIDSLEMLGSH 60 Query: 61 RQRVLAACQASSQQAIVIVHGTDTMQQTAQVLGQALTGKTVVLTGAMIPYEIANSDALFN 120 RQ++ AC + + +VI HGTDTM +TAQ L +TGKT+VLTGAM+PY +SD LFN Sbjct: 61 RQQIAEACARAPESRLVITHGTDTMPETAQHLAATITGKTIVLTGAMVPYAFGSSDGLFN 120 Query: 121 FGFACGVAQVLPAGVYVAMNGRIFAWNKVAKNRSAGVFE 159 G A AQ LP GVY+AMNGR FA V KNR GVFE Sbjct: 121 LGSALSFAQTLPEGVYIAMNGRYFAAGHVMKNREVGVFE 159 >B4UME7.1 B4UME7_ANASK Asparaginase Length = 167 Score = 184 bits (467), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 85/159 (53%), Positives = 116/159 (72%) Query: 3 LRIIATGGTFDKHYDEIAGQLGFGESHLPDVIARARITAEVSLEILPLLDSLEMQDGDRQ 62 +R+ TGGTFDK YDE++G+L F ++HLP+++ AR +VS+ L ++DSL+M DGDR+ Sbjct: 8 IRVFVTGGTFDKEYDELSGRLYFKDTHLPEMLRLARCRLDVSVRNLMMVDSLDMTDGDRR 67 Query: 63 RVLAACQASSQQAIVIVHGTDTMQQTAQVLGQALTGKTVVLTGAMIPYEIANSDALFNFG 122 ++ +C+++++ I++ HGTDTM +TA+ L A GKTVVLTGAMIPY +SD LFN G Sbjct: 68 IIVESCRSAAEDRILVTHGTDTMAETARALLAAGLGKTVVLTGAMIPYAFGSSDGLFNLG 127 Query: 123 FACGVAQVLPAGVYVAMNGRIFAWNKVAKNRSAGVFEPL 161 A QVLP GVYVAMNGR+F +KV KNR G FE L Sbjct: 128 SALSFVQVLPPGVYVAMNGRVFPGDKVRKNRQTGTFEDL 166