BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0521.p (261 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J103.1 D8J103_HERSS Dehydrogenase oxidoreductase protein EC=1.... 540 e-152 C5CPH1.1 C5CPH1_VARPS Short-chain dehydrogenase/reductase SDR 319 3e-85 A1WFW0.1 A1WFW0_VEREI Short-chain dehydrogenase/reductase SDR 318 5e-85 F0Q4V0.1 F0Q4V0_ACIAP Short-chain dehydrogenase/reductase SDR 318 6e-85 A1TPE8.1 A1TPE8_ACIAC Short-chain dehydrogenase/reductase SDR 310 1e-82 D2UD22.1 D2UD22_XANAP Hypothetical short-chain dehydrogenase/red... 304 7e-81 Q986V6.1 Q986V6_RHILO Putative oxidoreductase 298 5e-79 E1T9G1.1 E1T9G1_BURSG Short-chain dehydrogenase/reductase SDR 297 8e-79 E8TB49.1 E8TB49_MESCW Short-chain dehydrogenase/reductase SDR 293 1e-77 A4JBF8.1 A4JBF8_BURVG Short-chain dehydrogenase/reductase SDR 292 3e-77 >D8J103.1 D8J103_HERSS Dehydrogenase oxidoreductase protein EC=1.1.1.125 Length = 261 Score = 540 bits (1392), Expect = e-152, Method: Compositional matrix adjust. Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MSNTPQNVQLASFPSLKGKRVFITGGGTGIGAAIVEAFAQQGAHVAFVDIATEASEALCN 60 MSNTPQNVQLASFPSLKGKRVFITGGGTGIGAAIVEAFAQQGAHVAFVDIATEASEALCN Sbjct: 1 MSNTPQNVQLASFPSLKGKRVFITGGGTGIGAAIVEAFAQQGAHVAFVDIATEASEALCN 60 Query: 61 EVAAAGHPKPLFRHCDLRDIPAFQATIAELQAQLGDFDVLVNNAANDQRHKLEEVTLEYW 120 EVAAAGHPKPLFRHCDLRDIPAFQATIAELQAQLGDFDVLVNNAANDQRHKLEEVTLEYW Sbjct: 61 EVAAAGHPKPLFRHCDLRDIPAFQATIAELQAQLGDFDVLVNNAANDQRHKLEEVTLEYW 120 Query: 121 NDRIAINQRPSFFAVQSVVEGMKRRGGGSIINFSSISWHQSGGGFPVYTTAKASTLGLTR 180 NDRIAINQRPSFFAVQSVVEGMKRRGGGSIINFSSISWHQSGGGFPVYTTAKASTLGLTR Sbjct: 121 NDRIAINQRPSFFAVQSVVEGMKRRGGGSIINFSSISWHQSGGGFPVYTTAKASTLGLTR 180 Query: 181 GLARDLGPHKIRVNTVTPGWVMTERQIKLWLDEEGKKAIARNQCLQGDLLPWHLARMVLF 240 GLARDLGPHKIRVNTVTPGWVMTERQIKLWLDEEGKKAIARNQCLQGDLLPWHLARMVLF Sbjct: 181 GLARDLGPHKIRVNTVTPGWVMTERQIKLWLDEEGKKAIARNQCLQGDLLPWHLARMVLF 240 Query: 241 LAADDSAMCTAQEFIVDAGWV 261 LAADDSAMCTAQEFIVDAGWV Sbjct: 241 LAADDSAMCTAQEFIVDAGWV 261 >C5CPH1.1 C5CPH1_VARPS Short-chain dehydrogenase/reductase SDR Length = 258 Score = 319 bits (817), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 158/261 (60%), Positives = 198/261 (75%), Gaps = 3/261 (1%) Query: 1 MSNTPQNVQLASFPSLKGKRVFITGGGTGIGAAIVEAFAQQGAHVAFVDIATEASEALCN 60 M ++PQ L+ PSLKG+ VF+TGGG+GIGAA+V AFA QGA VAFVDIA AS AL Sbjct: 1 MKDSPQ---LSIHPSLKGRTVFVTGGGSGIGAAMVAAFAAQGARVAFVDIAEGASAALAQ 57 Query: 61 EVAAAGHPKPLFRHCDLRDIPAFQATIAELQAQLGDFDVLVNNAANDQRHKLEEVTLEYW 120 +A GH P +R CD+RDI A Q IA+ A+LGDF VLVNN A+D RH LE VT +Y+ Sbjct: 58 RIAQEGHAAPWWRACDVRDIGALQKAIADAAAELGDFAVLVNNVASDDRHTLESVTPDYY 117 Query: 121 NDRIAINQRPSFFAVQSVVEGMKRRGGGSIINFSSISWHQSGGGFPVYTTAKASTLGLTR 180 ++R+AIN+RP+ FA+QSVV GM+R G GS+IN S W G G+P Y AK+S GLTR Sbjct: 118 DNRMAINERPALFAIQSVVPGMRRLGFGSVINLGSTGWQTKGSGYPCYAIAKSSVNGLTR 177 Query: 181 GLARDLGPHKIRVNTVTPGWVMTERQIKLWLDEEGKKAIARNQCLQGDLLPWHLARMVLF 240 GLA +LG +IR+NTV+PGWVMTERQ++LWLD+EG++++ RNQCL L+P +ARMVLF Sbjct: 178 GLAVELGRDRIRINTVSPGWVMTERQVQLWLDDEGEQSLKRNQCLPDKLMPEDIARMVLF 237 Query: 241 LAADDSAMCTAQEFIVDAGWV 261 LA+DD+ MCTAQEF VDAGW Sbjct: 238 LASDDARMCTAQEFTVDAGWT 258 >A1WFW0.1 A1WFW0_VEREI Short-chain dehydrogenase/reductase SDR Length = 270 Score = 318 bits (815), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 161/251 (64%), Positives = 196/251 (78%) Query: 10 LASFPSLKGKRVFITGGGTGIGAAIVEAFAQQGAHVAFVDIATEASEALCNEVAAAGHPK 69 A FPSL + VF+TGGG+GIGAAIV AFA+QGA VAFVD+A ASE+L ++A AGHP+ Sbjct: 19 FAHFPSLANRAVFVTGGGSGIGAAIVSAFARQGARVAFVDVARPASESLAQQLADAGHPR 78 Query: 70 PLFRHCDLRDIPAFQATIAELQAQLGDFDVLVNNAANDQRHKLEEVTLEYWNDRIAINQR 129 P +R CD+RD+ A QA+I + AQLGDF VLVNN AND RH LE VT Y+++R+A+N+R Sbjct: 79 PWWRVCDVRDVAALQASIGDAAAQLGDFSVLVNNVANDDRHSLESVTPAYYDERMAVNER 138 Query: 130 PSFFAVQSVVEGMKRRGGGSIINFSSISWHQSGGGFPVYTTAKASTLGLTRGLARDLGPH 189 P+FFA+Q+VV GM+R G GS+IN S+SW GF YT AKAS GLTRGLA+ LG Sbjct: 139 PAFFAIQAVVPGMRRLGAGSVINLGSVSWQSKTPGFACYTIAKASVNGLTRGLAKTLGQD 198 Query: 190 KIRVNTVTPGWVMTERQIKLWLDEEGKKAIARNQCLQGDLLPWHLARMVLFLAADDSAMC 249 +IR+NTV+PGWVMTERQIKLWLD EG++ I RNQCL L +ARMVLFLA+DD+AMC Sbjct: 199 RIRINTVSPGWVMTERQIKLWLDAEGEQEIRRNQCLPDRLQAHDIARMVLFLASDDAAMC 258 Query: 250 TAQEFIVDAGW 260 TAQEF VDAGW Sbjct: 259 TAQEFKVDAGW 269 >F0Q4V0.1 F0Q4V0_ACIAP Short-chain dehydrogenase/reductase SDR Length = 271 Score = 318 bits (814), Expect = 6e-85, Method: Compositional matrix adjust. Identities = 158/252 (62%), Positives = 197/252 (78%) Query: 10 LASFPSLKGKRVFITGGGTGIGAAIVEAFAQQGAHVAFVDIATEASEALCNEVAAAGHPK 69 L+ FPSL+G+ VF+TGGG+GIGAAIV AFA+QGA VAFVD+A EAS L +++ AAG P+ Sbjct: 20 LSVFPSLRGRVVFVTGGGSGIGAAIVTAFAEQGARVAFVDVAREASAQLASDLEAAGLPR 79 Query: 70 PLFRHCDLRDIPAFQATIAELQAQLGDFDVLVNNAANDQRHKLEEVTLEYWNDRIAINQR 129 P +R CD+RDI A QA + + A+LGD VLVNN A+D RH LE VT Y+++R+AIN+R Sbjct: 80 PWWRECDVRDIDALQAAVRDAAAELGDVSVLVNNVASDDRHTLESVTPAYYDERMAINER 139 Query: 130 PSFFAVQSVVEGMKRRGGGSIINFSSISWHQSGGGFPVYTTAKASTLGLTRGLARDLGPH 189 P+FFA+Q+VV GM+R GGGSI+N S W G G+P Y AK+S GLTRGLAR LG Sbjct: 140 PAFFAIQAVVPGMRRLGGGSIVNLGSTGWQGKGSGYPCYAIAKSSVNGLTRGLARTLGQD 199 Query: 190 KIRVNTVTPGWVMTERQIKLWLDEEGKKAIARNQCLQGDLLPWHLARMVLFLAADDSAMC 249 +IR+NTV+PGWVMTERQI+LWLD EG++ + RNQCL L P +ARMVLFL +DD+AMC Sbjct: 200 RIRINTVSPGWVMTERQIRLWLDAEGERELERNQCLPDKLQPRDIARMVLFLGSDDAAMC 259 Query: 250 TAQEFIVDAGWV 261 TAQEF VDAGWV Sbjct: 260 TAQEFKVDAGWV 271 >A1TPE8.1 A1TPE8_ACIAC Short-chain dehydrogenase/reductase SDR Length = 271 Score = 310 bits (795), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 159/252 (63%), Positives = 198/252 (78%) Query: 10 LASFPSLKGKRVFITGGGTGIGAAIVEAFAQQGAHVAFVDIATEASEALCNEVAAAGHPK 69 L+ FPSL+G+ VF+TGGG+GIGAAIV AFA+QGA VAFVD+A EAS L ++ AAG P+ Sbjct: 20 LSVFPSLRGRVVFVTGGGSGIGAAIVTAFAEQGARVAFVDVAREASGQLVRDMEAAGLPR 79 Query: 70 PLFRHCDLRDIPAFQATIAELQAQLGDFDVLVNNAANDQRHKLEEVTLEYWNDRIAINQR 129 P +R CD+RDI A +A + + A+LGD VLVNN A+D RH LE VT EY+++R+AIN+R Sbjct: 80 PWWRECDVRDIDALRAALRDAAAELGDVSVLVNNVASDDRHTLESVTPEYYDERMAINER 139 Query: 130 PSFFAVQSVVEGMKRRGGGSIINFSSISWHQSGGGFPVYTTAKASTLGLTRGLARDLGPH 189 P+FFA+Q+VV GM+R GGGSI+N S W G G+P Y AK+S GLTRGLAR LG Sbjct: 140 PAFFAIQAVVPGMRRLGGGSIVNLGSTGWQGKGSGYPCYAIAKSSVNGLTRGLARTLGQD 199 Query: 190 KIRVNTVTPGWVMTERQIKLWLDEEGKKAIARNQCLQGDLLPWHLARMVLFLAADDSAMC 249 +IR+NTV+PGWVMTERQI+LWLD EG++ +ARNQCL L P +ARMVLFL +DD+AMC Sbjct: 200 RIRINTVSPGWVMTERQIRLWLDAEGERELARNQCLPDKLQPRDIARMVLFLGSDDAAMC 259 Query: 250 TAQEFIVDAGWV 261 TAQEF VDAGWV Sbjct: 260 TAQEFKVDAGWV 271 >D2UD22.1 D2UD22_XANAP Hypothetical short-chain dehydrogenase/reductase protein Length = 241 Score = 304 bits (779), Expect = 7e-81, Method: Compositional matrix adjust. Identities = 144/240 (60%), Positives = 179/240 (74%) Query: 21 VFITGGGTGIGAAIVEAFAQQGAHVAFVDIATEASEALCNEVAAAGHPKPLFRHCDLRDI 80 +FITGGG+GIGAA+VEAFA QGA VAFVD+A EAS AL +A AG KP +R CD+ D+ Sbjct: 1 MFITGGGSGIGAALVEAFAVQGAQVAFVDVAAEASAALVERLAGAGLVKPWWRRCDVTDV 60 Query: 81 PAFQATIAELQAQLGDFDVLVNNAANDQRHKLEEVTLEYWNDRIAINQRPSFFAVQSVVE 140 A QA I E +LGDF VL+NN +D RH L+ VT YW +AINQR +FFA+Q+VV Sbjct: 61 VALQAAIGEAATELGDFHVLLNNVGSDDRHALDAVTPAYWERCVAINQRAAFFAIQAVVP 120 Query: 141 GMKRRGGGSIINFSSISWHQSGGGFPVYTTAKASTLGLTRGLARDLGPHKIRVNTVTPGW 200 GM+R GGG+I+N S W GG+ VY TAK+S GLTRGLAR+LG +IR+N +TPGW Sbjct: 121 GMRRLGGGAIVNLGSTGWQTKTGGYAVYATAKSSVNGLTRGLARELGAARIRINVLTPGW 180 Query: 201 VMTERQIKLWLDEEGKKAIARNQCLQGDLLPWHLARMVLFLAADDSAMCTAQEFIVDAGW 260 VMTERQI LWLDE G++ +ARNQCL ++P +ARM LFLA+D++ TAQEF+VDAGW Sbjct: 181 VMTERQITLWLDEAGERELARNQCLPDKVMPEDIARMALFLASDEARAITAQEFVVDAGW 240 >Q986V6.1 Q986V6_RHILO Putative oxidoreductase Length = 258 Score = 298 bits (763), Expect = 5e-79, Method: Compositional matrix adjust. Identities = 142/255 (55%), Positives = 177/255 (69%) Query: 7 NVQLASFPSLKGKRVFITGGGTGIGAAIVEAFAQQGAHVAFVDIATEASEALCNEVAAAG 66 + A +PSLKG+ VFITGGG+GIG ++V F QG+ VAFVD++ E S L +AA G Sbjct: 4 EIGYAIYPSLKGRSVFITGGGSGIGESLVRHFCAQGSRVAFVDLSEEPSRHLVEAIAAEG 63 Query: 67 HPKPLFRHCDLRDIPAFQATIAELQAQLGDFDVLVNNAANDQRHKLEEVTLEYWNDRIAI 126 HP PLF CDLRD+ QA A+ G VL NNA ND RH+ ++VT+ YW+DR+A+ Sbjct: 64 HPAPLFIPCDLRDVEQLQAATAQAMQHNGPIQVLCNNAGNDDRHQTKDVTVAYWDDRMAV 123 Query: 127 NQRPSFFAVQSVVEGMKRRGGGSIINFSSISWHQSGGGFPVYTTAKASTLGLTRGLARDL 186 N R FFA Q+V M +GGGSIINF SI+W P Y TAKA+ G+TR LAR+L Sbjct: 124 NLRHQFFAAQAVRPQMSAQGGGSIINFGSITWMVGDPDCPAYVTAKAAVYGMTRALAREL 183 Query: 187 GPHKIRVNTVTPGWVMTERQIKLWLDEEGKKAIARNQCLQGDLLPWHLARMVLFLAADDS 246 GP +IRVN + PGWVMTERQ++LWL+ G++ IA QCL L P +ARM LFLAADDS Sbjct: 184 GPERIRVNCMVPGWVMTERQMRLWLNPAGERQIAERQCLPDRLQPADIARMALFLAADDS 243 Query: 247 AMCTAQEFIVDAGWV 261 MCT+Q+FIVDAGWV Sbjct: 244 RMCTSQQFIVDAGWV 258 >E1T9G1.1 E1T9G1_BURSG Short-chain dehydrogenase/reductase SDR Length = 266 Score = 297 bits (761), Expect = 8e-79, Method: Compositional matrix adjust. Identities = 147/254 (57%), Positives = 178/254 (70%), Gaps = 1/254 (0%) Query: 7 NVQLASFPSLKGKRVFITGGGTGIGAAIVEAFAQQGAHVAFVDIATEASEALCNEVAAAG 66 N A +PSL + V ITGG TGIGA+ VE FA QGA VAF DI A EAL +E+ + Sbjct: 13 NQSFARYPSLVDRTVLITGGATGIGASFVEHFAAQGARVAFFDIDATAGEALADELGDSK 72 Query: 67 HPKPLFRHCDLRDIPAFQATIAELQAQLGDFDVLVNNAANDQRHKLEEVTLEYWNDRIAI 126 H KPLF CDL DI A Q IA+++A LG VLVNNAAND+RH + EVT E ++ IA+ Sbjct: 73 H-KPLFMSCDLTDIDALQKAIADVKAALGPIQVLVNNAANDKRHTIGEVTRESFDAGIAV 131 Query: 127 NQRPSFFAVQSVVEGMKRRGGGSIINFSSISWHQSGGGFPVYTTAKASTLGLTRGLARDL 186 N R FFA Q+V+E MK GSIIN SISW GG+PVY +K++ GLTRGLARDL Sbjct: 132 NIRHQFFAAQAVIEDMKAARSGSIINLGSISWMLKNGGYPVYVMSKSAVQGLTRGLARDL 191 Query: 187 GPHKIRVNTVTPGWVMTERQIKLWLDEEGKKAIARNQCLQGDLLPWHLARMVLFLAADDS 246 GP +RVNT+ PGWVMTE+Q +LWLD+ G++AI QC+ +LLP LARM LFLAADDS Sbjct: 192 GPFNVRVNTLVPGWVMTEKQKRLWLDDAGRRAIKEGQCIDAELLPADLARMALFLAADDS 251 Query: 247 AMCTAQEFIVDAGW 260 M TAQ+ +VD GW Sbjct: 252 RMITAQDIVVDGGW 265 >E8TB49.1 E8TB49_MESCW Short-chain dehydrogenase/reductase SDR Length = 258 Score = 293 bits (751), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 140/255 (54%), Positives = 175/255 (68%) Query: 7 NVQLASFPSLKGKRVFITGGGTGIGAAIVEAFAQQGAHVAFVDIATEASEALCNEVAAAG 66 + A +PSLKG+ VFITGGG+GIG ++V F QG+ VAFVD+A E S+ L + +AA G Sbjct: 4 EIGYAIYPSLKGRSVFITGGGSGIGESLVRHFCAQGSRVAFVDMAEEPSQRLVDAIAAEG 63 Query: 67 HPKPLFRHCDLRDIPAFQATIAELQAQLGDFDVLVNNAANDQRHKLEEVTLEYWNDRIAI 126 H PLF CDLR++ QA + G L NNA ND RH+ ++VT+ YW+DR+A+ Sbjct: 64 HAAPLFIPCDLRNVEELQAATVQAMQHNGPIQALCNNAGNDDRHQTKDVTVAYWDDRMAV 123 Query: 127 NQRPSFFAVQSVVEGMKRRGGGSIINFSSISWHQSGGGFPVYTTAKASTLGLTRGLARDL 186 N R FFA Q+V M +GGGSIINF SI+W P Y TAKA G+TR LAR+L Sbjct: 124 NLRHQFFAAQAVRPQMSAQGGGSIINFGSITWMVGDPDCPAYVTAKAGIYGMTRALAREL 183 Query: 187 GPHKIRVNTVTPGWVMTERQIKLWLDEEGKKAIARNQCLQGDLLPWHLARMVLFLAADDS 246 GP +IRVN + PGWVMTERQ++LWLD G++ IA QCL L P +ARM LFLAADDS Sbjct: 184 GPERIRVNCMVPGWVMTERQMRLWLDPAGERQIAERQCLPDRLQPSDIARMALFLAADDS 243 Query: 247 AMCTAQEFIVDAGWV 261 MCT+Q+FIVDAGWV Sbjct: 244 RMCTSQQFIVDAGWV 258 >A4JBF8.1 A4JBF8_BURVG Short-chain dehydrogenase/reductase SDR Length = 265 Score = 292 bits (748), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 145/264 (54%), Positives = 184/264 (69%), Gaps = 6/264 (2%) Query: 1 MSNTPQNVQLASFPSLKGKRVFITGGGTGIGAAIVEAFAQQGAHVAFVDIATEASEALCN 60 + + Q+ + A +PSL + V ITGG TGIGA+ VE FA+QGA VAFVD+ +A AL Sbjct: 3 LDTSAQHARYARYPSLADRAVLITGGATGIGASFVEHFARQGARVAFVDLDAQAGAALAE 62 Query: 61 EVAAAGHPK----PLFRHCDLRDIPAFQATIAELQAQLGDFDVLVNNAANDQRHKLEEVT 116 + G P+ PLF CDL DI A + TI ++A+LG DVLVNNAAND RH + +VT Sbjct: 63 RLV--GEPEVRHAPLFVACDLTDIDALRGTIDAIRARLGAIDVLVNNAANDARHAIADVT 120 Query: 117 LEYWNDRIAINQRPSFFAVQSVVEGMKRRGGGSIINFSSISWHQSGGGFPVYTTAKASTL 176 ++ IA+N R FFA Q+V++ MKR+GGG+IIN SISW GG+PVY AKA+ Sbjct: 121 PASFDAGIAVNLRHQFFAAQAVIDDMKRQGGGAIINLGSISWMLKNGGYPVYVMAKAAVQ 180 Query: 177 GLTRGLARDLGPHKIRVNTVTPGWVMTERQIKLWLDEEGKKAIARNQCLQGDLLPWHLAR 236 GLTRGLARDLGP IRVN++ PGWVMT++Q +LWLD+ G+ AI QC+ +LLP LAR Sbjct: 181 GLTRGLARDLGPFGIRVNSLVPGWVMTDKQRRLWLDDAGRAAIKAGQCIDAELLPDDLAR 240 Query: 237 MVLFLAADDSAMCTAQEFIVDAGW 260 M LFLAADDS M TAQ+ +VD GW Sbjct: 241 MALFLAADDSRMITAQDVVVDGGW 264