BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0451.p (209 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J1J7.1 D8J1J7_HERSS 2-keto-4-hydroxyglutarate aldolase/-keto-3... 409 e-113 A4G429.2 A4G429_HERAR Putative uncharacterized protein 327 8e-88 F1VXZ8.1 F1VXZ8_9BURK 4-Hydroxy-2-oxoglutarate aldolase 322 3e-86 A6T0F3.1 A6T0F3_JANMA 2-dehydro-3-deoxyphosphogluconate aldolase... 318 3e-85 C1HXX4.1 C1HXX4_NEIGO Keto-hydroxyglutarate-aldolase/keto-deoxy-... 235 4e-60 D6JLU5.1 D6JLU5_NEIGO 2-dehydro-3-deoxyphosphogluconate aldolase... 235 4e-60 D6H7N0.1 D6H7N0_NEIGO Keto-hydroxyglutarate-aldolase/keto-deoxy-... 235 4e-60 D1EFT8.1 D1EFT8_NEIGO Keto-hydroxyglutarate-aldolase/keto-deoxy-... 234 5e-60 D1E321.1 D1E321_NEIGO Keto-hydroxyglutarate-aldolase/keto-deoxy-... 234 5e-60 D1DCJ1.1 D1DCJ1_NEIGO Keto-hydroxyglutarate-aldolase/keto-deoxy-... 234 6e-60 >D8J1J7.1 D8J1J7_HERSS 2-keto-4-hydroxyglutarate aldolase/-keto-3-deoxy-6-phosphogluconate aldolase protein EC=4.1.2.14 EC=4.1.3.16 Length = 209 Score = 409 bits (1052), Expect = e-113, Method: Compositional matrix adjust. Identities = 208/208 (100%), Positives = 208/208 (100%) Query: 1 MKTTLEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESV 60 MKTTLEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESV Sbjct: 1 MKTTLEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESV 60 Query: 61 PDAIVGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAA 120 PDAIVGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAA Sbjct: 61 PDAIVGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAA 120 Query: 121 REAGFRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGS 180 REAGFRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGS Sbjct: 121 REAGFRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGS 180 Query: 181 WLTPKAAIEAGDWDKITEIAKAASALKK 208 WLTPKAAIEAGDWDKITEIAKAASALKK Sbjct: 181 WLTPKAAIEAGDWDKITEIAKAASALKK 208 >A4G429.2 A4G429_HERAR Putative uncharacterized protein Length = 206 Score = 327 bits (837), Expect = 8e-88, Method: Compositional matrix adjust. Identities = 162/203 (79%), Positives = 179/203 (88%) Query: 5 LEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESVPDAI 64 LEIMR SPVIPVIAID HAVPLARALVAGGIRVLE+TLRT++GL AIR IAE VP+AI Sbjct: 4 LEIMRCSPVIPVIAIDDLSHAVPLARALVAGGIRVLEVTLRTQYGLAAIREIAEQVPEAI 63 Query: 65 VGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAAREAG 124 +GVGTLT E+F A+RDAGA+FGVSPGLT LIE A+ SGLPLLPGVMTPSEVM AREAG Sbjct: 64 LGVGTLTRHEDFAAARDAGAIFGVSPGLTKELIEGARSSGLPLLPGVMTPSEVMRAREAG 123 Query: 125 FRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGSWLTP 184 FRQ+KLFPAVPAGGVGMLN IAGPL D+ FCPTGGI+QETA QFLACKNV CVGGSWLTP Sbjct: 124 FRQVKLFPAVPAGGVGMLNAIAGPLPDMLFCPTGGISQETAAQFLACKNVACVGGSWLTP 183 Query: 185 KAAIEAGDWDKITEIAKAASALK 207 K A+ AGDW ++T +AKAASAL+ Sbjct: 184 KDALAAGDWARVTALAKAASALR 206 >F1VXZ8.1 F1VXZ8_9BURK 4-Hydroxy-2-oxoglutarate aldolase Length = 220 Score = 322 bits (824), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 163/197 (82%), Positives = 172/197 (87%) Query: 1 MKTTLEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESV 60 M L IMR SPVIPVIAID +HAVPLARALVAGGIRVLE+TLRT HGL AIRAIA V Sbjct: 12 MPDLLHIMRVSPVIPVIAIDDLDHAVPLARALVAGGIRVLEVTLRTVHGLAAIRAIAGQV 71 Query: 61 PDAIVGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAA 120 PDAI+GVGTLT PEEF A+RDAGAVFGVSPGLTPALI AA+ SGLPLLPGVMTPSEVMAA Sbjct: 72 PDAILGVGTLTLPEEFAAARDAGAVFGVSPGLTPALIAAARSSGLPLLPGVMTPSEVMAA 131 Query: 121 REAGFRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGS 180 REAGFRQLKLFPAVPAGGVGML IAGPL DV FCPTGGI+ TAPQFLACKNV CVGGS Sbjct: 132 REAGFRQLKLFPAVPAGGVGMLGAIAGPLGDVMFCPTGGISLATAPQFLACKNVACVGGS 191 Query: 181 WLTPKAAIEAGDWDKIT 197 WLTPK A+ +GDW +IT Sbjct: 192 WLTPKDAMLSGDWARIT 208 >A6T0F3.1 A6T0F3_JANMA 2-dehydro-3-deoxyphosphogluconate aldolase EC=4.1.2.14 Length = 206 Score = 318 bits (815), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 159/193 (82%), Positives = 171/193 (88%) Query: 5 LEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESVPDAI 64 LEIMRASPVIPVIAID HAVPLARALVAGGIRVLE+TLRT+HGL AIRAIAE VP+AI Sbjct: 4 LEIMRASPVIPVIAIDDLTHAVPLARALVAGGIRVLEVTLRTQHGLAAIRAIAEQVPEAI 63 Query: 65 VGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAAREAG 124 +GVGTLT E+F A+RDAGAVFGVSPGLT LI+ + SGLPLLPGVMTPSEVMAAREAG Sbjct: 64 LGVGTLTRSEDFAAARDAGAVFGVSPGLTRELIQGSLASGLPLLPGVMTPSEVMAAREAG 123 Query: 125 FRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGSWLTP 184 F QLKLFPAVPAGGVGMLN IAGPL DV FCPTGGI+QETA QFLACKNV CVGGSWLTP Sbjct: 124 FHQLKLFPAVPAGGVGMLNAIAGPLPDVLFCPTGGISQETAAQFLACKNVACVGGSWLTP 183 Query: 185 KAAIEAGDWDKIT 197 K A+ AGDW ++T Sbjct: 184 KDALAAGDWGRVT 196 >C1HXX4.1 C1HXX4_NEIGO Keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase Length = 212 Score = 235 bits (599), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 123/205 (60%), Positives = 145/205 (70%) Query: 3 TTLEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESVPD 62 T EI+ A V+PV+AID AV L+RALV GGI LEITLRT GL AIR IA+ VP+ Sbjct: 5 TPREILTAGAVVPVMAIDDLSTAVDLSRALVEGGIPTLEITLRTPVGLEAIRLIAKEVPN 64 Query: 63 AIVGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAARE 122 AIVG GT+T+PE+ A DAGAVF +SPGL +L A + SG+PL+PGV TP EV A E Sbjct: 65 AIVGAGTVTNPEQLKAVEDAGAVFAISPGLHESLARAGRNSGIPLIPGVATPGEVQLALE 124 Query: 123 AGFRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGSWL 182 G LKLFPA GG ML + GP ADV FCPTGGI+ TAP +LA NV+CVGGSWL Sbjct: 125 HGIDTLKLFPAEVVGGKAMLKALYGPYADVRFCPTGGISLATAPDYLALPNVLCVGGSWL 184 Query: 183 TPKAAIEAGDWDKITEIAKAASALK 207 TPK A++ DWD IT +AK A+ALK Sbjct: 185 TPKEAVKNKDWDTITRLAKEAAALK 209 >D6JLU5.1 D6JLU5_NEIGO 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Length = 226 Score = 235 bits (599), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 123/205 (60%), Positives = 145/205 (70%) Query: 3 TTLEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESVPD 62 T EI+ A V+PV+AID AV L+RALV GGI LEITLRT GL AIR IA+ VP+ Sbjct: 19 TPREILTAGAVVPVMAIDDLSTAVDLSRALVEGGIPTLEITLRTPVGLEAIRLIAKEVPN 78 Query: 63 AIVGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAARE 122 AIVG GT+T+PE+ A DAGAVF +SPGL +L A + SG+PL+PGV TP EV A E Sbjct: 79 AIVGAGTVTNPEQLKAVEDAGAVFAISPGLHESLARAGRNSGIPLIPGVATPGEVQLALE 138 Query: 123 AGFRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGSWL 182 G LKLFPA GG ML + GP ADV FCPTGGI+ TAP +LA NV+CVGGSWL Sbjct: 139 HGIDTLKLFPAEVVGGKAMLKALYGPYADVRFCPTGGISLATAPDYLALPNVLCVGGSWL 198 Query: 183 TPKAAIEAGDWDKITEIAKAASALK 207 TPK A++ DWD IT +AK A+ALK Sbjct: 199 TPKEAVKNKDWDTITRLAKEAAALK 223 >D6H7N0.1 D6H7N0_NEIGO Keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase Length = 226 Score = 235 bits (599), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 123/205 (60%), Positives = 145/205 (70%) Query: 3 TTLEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESVPD 62 T EI+ A V+PV+AID AV L+RALV GGI LEITLRT GL AIR IA+ VP+ Sbjct: 19 TPREILTAGAVVPVMAIDDLSTAVDLSRALVEGGIPTLEITLRTPVGLEAIRLIAKEVPN 78 Query: 63 AIVGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAARE 122 AIVG GT+T+PE+ A DAGAVF +SPGL +L A + SG+PL+PGV TP EV A E Sbjct: 79 AIVGAGTVTNPEQLKAVEDAGAVFAISPGLHESLARAGRNSGIPLIPGVATPGEVQLALE 138 Query: 123 AGFRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGSWL 182 G LKLFPA GG ML + GP ADV FCPTGGI+ TAP +LA NV+CVGGSWL Sbjct: 139 HGIDTLKLFPAEVVGGKAMLKALYGPYADVRFCPTGGISLATAPDYLALPNVLCVGGSWL 198 Query: 183 TPKAAIEAGDWDKITEIAKAASALK 207 TPK A++ DWD IT +AK A+ALK Sbjct: 199 TPKEAVKNKDWDTITRLAKEAAALK 223 >D1EFT8.1 D1EFT8_NEIGO Keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase Length = 212 Score = 234 bits (597), Expect = 5e-60, Method: Compositional matrix adjust. Identities = 122/205 (59%), Positives = 145/205 (70%) Query: 3 TTLEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESVPD 62 T EI+ A V+PV+AID AV L+RALV GGI LEITLRT GL AIR IA+ VP+ Sbjct: 5 TPREILTAGAVVPVMAIDDLSTAVDLSRALVEGGIPTLEITLRTPVGLEAIRLIAKEVPN 64 Query: 63 AIVGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAARE 122 AI+G GT+T+PE+ A DAGAVF +SPGL +L A + SG+PL+PGV TP EV A E Sbjct: 65 AIIGAGTVTNPEQLKAVEDAGAVFAISPGLHESLARAGRNSGIPLIPGVATPGEVQLALE 124 Query: 123 AGFRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGSWL 182 G LKLFPA GG ML + GP ADV FCPTGGI+ TAP +LA NV+CVGGSWL Sbjct: 125 HGIDTLKLFPAEVVGGKAMLKALYGPYADVRFCPTGGISLATAPDYLALPNVLCVGGSWL 184 Query: 183 TPKAAIEAGDWDKITEIAKAASALK 207 TPK A++ DWD IT +AK A+ALK Sbjct: 185 TPKEAVKNKDWDTITRLAKEAAALK 209 >D1E321.1 D1E321_NEIGO Keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase Length = 212 Score = 234 bits (597), Expect = 5e-60, Method: Compositional matrix adjust. Identities = 122/205 (59%), Positives = 145/205 (70%) Query: 3 TTLEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESVPD 62 T EI+ A V+PV+AID AV L+RALV GGI LEITLRT GL AIR IA+ VP+ Sbjct: 5 TPREILTAGAVVPVMAIDDLSTAVDLSRALVEGGIPTLEITLRTPVGLEAIRLIAKEVPN 64 Query: 63 AIVGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAARE 122 AI+G GT+T+PE+ A DAGAVF +SPGL +L A + SG+PL+PGV TP EV A E Sbjct: 65 AIIGAGTVTNPEQLKAVEDAGAVFAISPGLHESLARAGRNSGIPLIPGVATPGEVQLALE 124 Query: 123 AGFRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGSWL 182 G LKLFPA GG ML + GP ADV FCPTGGI+ TAP +LA NV+CVGGSWL Sbjct: 125 HGIDTLKLFPAEVVGGKAMLKALYGPYADVRFCPTGGISLATAPDYLALPNVLCVGGSWL 184 Query: 183 TPKAAIEAGDWDKITEIAKAASALK 207 TPK A++ DWD IT +AK A+ALK Sbjct: 185 TPKEAVKNKDWDTITRLAKEAAALK 209 >D1DCJ1.1 D1DCJ1_NEIGO Keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase Length = 226 Score = 234 bits (597), Expect = 6e-60, Method: Compositional matrix adjust. Identities = 122/205 (59%), Positives = 145/205 (70%) Query: 3 TTLEIMRASPVIPVIAIDKFEHAVPLARALVAGGIRVLEITLRTEHGLPAIRAIAESVPD 62 T EI+ A V+PV+AID AV L+RALV GGI LEITLRT GL AIR IA+ VP+ Sbjct: 19 TPREILTAGAVVPVMAIDDLSTAVDLSRALVEGGIPTLEITLRTPVGLEAIRLIAKEVPN 78 Query: 63 AIVGVGTLTSPEEFTASRDAGAVFGVSPGLTPALIEAAKRSGLPLLPGVMTPSEVMAARE 122 AI+G GT+T+PE+ A DAGAVF +SPGL +L A + SG+PL+PGV TP EV A E Sbjct: 79 AIIGAGTVTNPEQLKAVEDAGAVFAISPGLHESLARAGRNSGIPLIPGVATPGEVQLALE 138 Query: 123 AGFRQLKLFPAVPAGGVGMLNGIAGPLADVSFCPTGGITQETAPQFLACKNVVCVGGSWL 182 G LKLFPA GG ML + GP ADV FCPTGGI+ TAP +LA NV+CVGGSWL Sbjct: 139 HGIDTLKLFPAEVVGGKAMLKALYGPYADVRFCPTGGISLATAPDYLALPNVLCVGGSWL 198 Query: 183 TPKAAIEAGDWDKITEIAKAASALK 207 TPK A++ DWD IT +AK A+ALK Sbjct: 199 TPKEAVKNKDWDTITRLAKEAAALK 223