BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0441.p (249 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J1K5.1 D8J1K5_HERSS Dehydrogenase protein EC=1.1.1.100 491 e-137 B1XZF8.1 B1XZF8_LEPCP Short-chain dehydrogenase/reductase SDR 423 e-116 C5CRX5.1 C5CRX5_VARPS Short-chain dehydrogenase/reductase SDR 419 e-115 D8IXF5.1 D8IXF5_HERSS 3-oxoacyl-[acyl-carrier-protein] reductase... 410 e-112 A9BRL7.1 A9BRL7_DELAS Short-chain dehydrogenase/reductase SDR 395 e-108 Q12DJ0.1 Q12DJ0_POLSJ Short-chain dehydrogenase/reductase SDR 367 e-100 B1XX33.1 B1XX33_LEPCP Short-chain dehydrogenase/reductase SDR 363 9e-99 E8TQ66.1 E8TQ66_ALIDB Short-chain dehydrogenase/reductase SDR 362 2e-98 Q46RW1.1 Q46RW1_CUPPJ NAD-dependent epimerase/dehydratase:Short-... 336 2e-90 D5WL89.1 D5WL89_BURSC Short-chain dehydrogenase/reductase SDR 333 1e-89 >D8J1K5.1 D8J1K5_HERSS Dehydrogenase protein EC=1.1.1.100 Length = 249 Score = 491 bits (1265), Expect = e-137, Method: Compositional matrix adjust. Identities = 248/249 (99%), Positives = 249/249 (100%) Query: 1 MLLKDKVAVITGGAGINGLGYATARLMAEQGARVVVLDLAQADPAAAAARIGSQHLGLVA 60 MLLKDKVAVITGGAGINGLGYATARLMAEQGARVVVLDLAQADPAAAAARIGSQHLGLVA Sbjct: 1 MLLKDKVAVITGGAGINGLGYATARLMAEQGARVVVLDLAQADPAAAAARIGSQHLGLVA 60 Query: 61 DVTDKASCDTAAAAILQQFGRIDILVNNAGITQPVKTLEITGADYDRILDVSLRGTLYMS 120 DVTDKASC+TAAAAILQQFGRIDILVNNAGITQPVKTLEITGADYDRILDVSLRGTLYMS Sbjct: 61 DVTDKASCETAAAAILQQFGRIDILVNNAGITQPVKTLEITGADYDRILDVSLRGTLYMS 120 Query: 121 QAVLPAMRAQQNGSIICISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREFGPEGIRV 180 QAVLPAMRAQQNGSIICISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREFGPEGIRV Sbjct: 121 QAVLPAMRAQQNGSIICISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREFGPEGIRV 180 Query: 181 NSITPGLIGTDIIKGKLTEEKKAEIAETIPLARLGRADDIGGACVFLGSDLSQYCTGITL 240 NSITPGLIGTDIIKGKLTEEKKAEIAETIPLARLGRADDIGGACVFLGSDLSQYCTGITL Sbjct: 181 NSITPGLIGTDIIKGKLTEEKKAEIAETIPLARLGRADDIGGACVFLGSDLSQYCTGITL 240 Query: 241 DVNGGMLIH 249 DVNGGMLIH Sbjct: 241 DVNGGMLIH 249 >B1XZF8.1 B1XZF8_LEPCP Short-chain dehydrogenase/reductase SDR Length = 249 Score = 423 bits (1088), Expect = e-116, Method: Compositional matrix adjust. Identities = 222/249 (89%), Positives = 238/249 (95%) Query: 1 MLLKDKVAVITGGAGINGLGYATARLMAEQGARVVVLDLAQADPAAAAARIGSQHLGLVA 60 MLLKDKVAVITGGAG+NGLG+ATARLMA QGARVVVLDLA A+PAAAAA++G+ HLG VA Sbjct: 1 MLLKDKVAVITGGAGLNGLGFATARLMAAQGARVVVLDLAGAEPAAAAAQLGAGHLGWVA 60 Query: 61 DVTDKASCDTAAAAILQQFGRIDILVNNAGITQPVKTLEITGADYDRILDVSLRGTLYMS 120 DVTDKASCD AAAA+LQ +GRID+LVNNAGITQP KTL+ITGADYDRILDVSLRGTLYMS Sbjct: 61 DVTDKASCDAAAAAVLQAYGRIDVLVNNAGITQPAKTLDITGADYDRILDVSLRGTLYMS 120 Query: 121 QAVLPAMRAQQNGSIICISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREFGPEGIRV 180 QAVLPAM+ Q++GSI+CISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREFGP+GIR+ Sbjct: 121 QAVLPAMQQQKSGSIVCISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREFGPDGIRI 180 Query: 181 NSITPGLIGTDIIKGKLTEEKKAEIAETIPLARLGRADDIGGACVFLGSDLSQYCTGITL 240 N ITPGLIGTDIIKGKLTEEKKAEIAETIPLARLGRADDIGGACVFL SDLS YCTGITL Sbjct: 181 NCITPGLIGTDIIKGKLTEEKKAEIAETIPLARLGRADDIGGACVFLASDLSLYCTGITL 240 Query: 241 DVNGGMLIH 249 DVNGGMLIH Sbjct: 241 DVNGGMLIH 249 >C5CRX5.1 C5CRX5_VARPS Short-chain dehydrogenase/reductase SDR Length = 249 Score = 419 bits (1076), Expect = e-115, Method: Compositional matrix adjust. Identities = 214/249 (85%), Positives = 230/249 (92%) Query: 1 MLLKDKVAVITGGAGINGLGYATARLMAEQGARVVVLDLAQADPAAAAARIGSQHLGLVA 60 MLLKDK+ VITGGAG+NGLG+ATARLMA GARV VLDL +A PAAAAA++G HLG+VA Sbjct: 1 MLLKDKIVVITGGAGVNGLGFATARLMAAHGARVAVLDLERAAPAAAAAQLGPAHLGIVA 60 Query: 61 DVTDKASCDTAAAAILQQFGRIDILVNNAGITQPVKTLEITGADYDRILDVSLRGTLYMS 120 DVTDKASCD AAA +L+ FGRID LVNNAGITQPVKTLEI+GADYDRILDVSLRGTLYMS Sbjct: 61 DVTDKASCDAAAATVLKAFGRIDTLVNNAGITQPVKTLEISGADYDRILDVSLRGTLYMS 120 Query: 121 QAVLPAMRAQQNGSIICISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREFGPEGIRV 180 QAVLP+M+ Q GSI+CISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREFGPEGIR+ Sbjct: 121 QAVLPSMQQQGGGSIVCISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREFGPEGIRI 180 Query: 181 NSITPGLIGTDIIKGKLTEEKKAEIAETIPLARLGRADDIGGACVFLGSDLSQYCTGITL 240 NSITPGLIGTDIIKG+LTEEKKAEIAETIPL RLGRA+DI GACVFL SDLS YCTGITL Sbjct: 181 NSITPGLIGTDIIKGRLTEEKKAEIAETIPLGRLGRANDIAGACVFLASDLSLYCTGITL 240 Query: 241 DVNGGMLIH 249 DVNGGMLIH Sbjct: 241 DVNGGMLIH 249 >D8IXF5.1 D8IXF5_HERSS 3-oxoacyl-[acyl-carrier-protein] reductase protein EC=1.1.1.100 Length = 249 Score = 410 bits (1053), Expect = e-112, Method: Compositional matrix adjust. Identities = 208/249 (83%), Positives = 230/249 (92%) Query: 1 MLLKDKVAVITGGAGINGLGYATARLMAEQGARVVVLDLAQADPAAAAARIGSQHLGLVA 60 MLLKDKVA+ITGGAG NGLG++TARLMA QGAR+V+LDL +A+PA AAAR+G+QHLGLVA Sbjct: 1 MLLKDKVAIITGGAGQNGLGFSTARLMAAQGARIVILDLERAEPAGAAARLGAQHLGLVA 60 Query: 61 DVTDKASCDTAAAAILQQFGRIDILVNNAGITQPVKTLEITGADYDRILDVSLRGTLYMS 120 DVTDKA+C+ AAAA+L+QFGRIDILVNNAG+TQP K LEITG DYDRILDVSLRGTLYMS Sbjct: 61 DVTDKAACEAAAAAVLKQFGRIDILVNNAGVTQPAKLLEITGKDYDRILDVSLRGTLYMS 120 Query: 121 QAVLPAMRAQQNGSIICISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREFGPEGIRV 180 QAVLPAM+AQQ+GSI+CISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREFGP+GIRV Sbjct: 121 QAVLPAMQAQQSGSIVCISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREFGPQGIRV 180 Query: 181 NSITPGLIGTDIIKGKLTEEKKAEIAETIPLARLGRADDIGGACVFLGSDLSQYCTGITL 240 N ITPGLI TDI K L+ EKKAEIA+TIPL RLG DD+GG CVFL SDLSQYCTG+TL Sbjct: 181 NCITPGLISTDINKDILSAEKKAEIAQTIPLGRLGGPDDVGGVCVFLASDLSQYCTGVTL 240 Query: 241 DVNGGMLIH 249 DVNGGMLIH Sbjct: 241 DVNGGMLIH 249 >A9BRL7.1 A9BRL7_DELAS Short-chain dehydrogenase/reductase SDR Length = 249 Score = 395 bits (1014), Expect = e-108, Method: Compositional matrix adjust. Identities = 200/249 (80%), Positives = 221/249 (88%) Query: 1 MLLKDKVAVITGGAGINGLGYATARLMAEQGARVVVLDLAQADPAAAAARIGSQHLGLVA 60 MLLKD+VA+ITGGAGINGLG+ATAR MA QGARV +LDL +ADPA AAAR+G HLGLVA Sbjct: 1 MLLKDRVAIITGGAGINGLGFATARQMAAQGARVAILDLERADPAGAAARLGDGHLGLVA 60 Query: 61 DVTDKASCDTAAAAILQQFGRIDILVNNAGITQPVKTLEITGADYDRILDVSLRGTLYMS 120 DVTDK SC+ AAAA+L+ FGRID LVNNAGITQ V TLEI GADYDR+LDVSLRGTLYMS Sbjct: 61 DVTDKPSCEAAAAAVLRAFGRIDALVNNAGITQAVGTLEIGGADYDRVLDVSLRGTLYMS 120 Query: 121 QAVLPAMRAQQNGSIICISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREFGPEGIRV 180 QAVLP+MR QQ G+I+CISSVSAQRGGGI GGPHYSAAKAGVLGLARAMAREFG +GIR+ Sbjct: 121 QAVLPSMRRQQAGAIVCISSVSAQRGGGIFGGPHYSAAKAGVLGLARAMAREFGGDGIRI 180 Query: 181 NSITPGLIGTDIIKGKLTEEKKAEIAETIPLARLGRADDIGGACVFLGSDLSQYCTGITL 240 N +TPGLI TDI +GKL E+K EI+ TIPLARLGRADD+ GACVFL SDL+ YCTGITL Sbjct: 181 NCVTPGLIETDITQGKLGPERKREISATIPLARLGRADDVAGACVFLASDLAGYCTGITL 240 Query: 241 DVNGGMLIH 249 DVNGGMLIH Sbjct: 241 DVNGGMLIH 249 >Q12DJ0.1 Q12DJ0_POLSJ Short-chain dehydrogenase/reductase SDR Length = 249 Score = 367 bits (942), Expect = e-100, Method: Compositional matrix adjust. Identities = 187/249 (75%), Positives = 214/249 (85%) Query: 1 MLLKDKVAVITGGAGINGLGYATARLMAEQGARVVVLDLAQADPAAAAARIGSQHLGLVA 60 MLLKD+VAV+TGGAG NGLG+ATAR+MA QGA +++LDL+QADPAAAAAR+G QH+GLVA Sbjct: 1 MLLKDRVAVVTGGAGPNGLGFATARMMAAQGATIIILDLSQADPAAAAARLGPQHMGLVA 60 Query: 61 DVTDKASCDTAAAAILQQFGRIDILVNNAGITQPVKTLEITGADYDRILDVSLRGTLYMS 120 DVT+KASCDTA AA+L GRIDILVNNAGITQP KTL+I+ DYD +LDVSLRGTL S Sbjct: 61 DVTNKASCDTAVAAVLDAKGRIDILVNNAGITQPRKTLDISPEDYDAVLDVSLRGTLVAS 120 Query: 121 QAVLPAMRAQQNGSIICISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREFGPEGIRV 180 QAVLP M AQ+ GSI+CISSVSAQRGGGILGGPHYSAAKAGVLGLARAMARE+G +GIRV Sbjct: 121 QAVLPTMLAQKQGSIVCISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREYGGQGIRV 180 Query: 181 NSITPGLIGTDIIKGKLTEEKKAEIAETIPLARLGRADDIGGACVFLGSDLSQYCTGITL 240 N +TPGLI TDI KGK+ ++K+ I + IPL +G DD+ G VFL SDLS YCTGITL Sbjct: 181 NCVTPGLIATDINKGKIPDDKRQAILDGIPLGYIGAPDDVAGCVVFLASDLSGYCTGITL 240 Query: 241 DVNGGMLIH 249 DVNGGMLIH Sbjct: 241 DVNGGMLIH 249 >B1XX33.1 B1XX33_LEPCP Short-chain dehydrogenase/reductase SDR Length = 249 Score = 363 bits (933), Expect = 9e-99, Method: Compositional matrix adjust. Identities = 187/249 (75%), Positives = 218/249 (87%) Query: 1 MLLKDKVAVITGGAGINGLGYATARLMAEQGARVVVLDLAQADPAAAAARIGSQHLGLVA 60 MLLKDKVA+ITGGAG NGLG+ATAR+MAEQGAR+V+LDLAQADPA AAAR+G QH+G+VA Sbjct: 1 MLLKDKVALITGGAGPNGLGFATARMMAEQGARIVILDLAQADPAGAAARLGPQHIGVVA 60 Query: 61 DVTDKASCDTAAAAILQQFGRIDILVNNAGITQPVKTLEITGADYDRILDVSLRGTLYMS 120 DVTDKASC+ AA +L+ GRID+LVNNAGITQP KT++ITGADYD +LDVSLRGTLYMS Sbjct: 61 DVTDKASCELAARTVLETCGRIDVLVNNAGITQPRKTVDITGADYDAVLDVSLRGTLYMS 120 Query: 121 QAVLPAMRAQQNGSIICISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREFGPEGIRV 180 QAVLPAMRAQ+ G+I+CISSVSAQRGGGILGGPHYSAAKAGVLGLARAMARE+G + +R+ Sbjct: 121 QAVLPAMRAQKGGAIVCISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREYGNDNVRI 180 Query: 181 NSITPGLIGTDIIKGKLTEEKKAEIAETIPLARLGRADDIGGACVFLGSDLSQYCTGITL 240 N +TPGLI TDI KG + ++ I E IPL R+G DD+ G VFL SDL++YCTG+TL Sbjct: 181 NCVTPGLIATDINKGLIPADRMVGILEQIPLNRIGGPDDVAGCVVFLASDLARYCTGVTL 240 Query: 241 DVNGGMLIH 249 DVNGGMLIH Sbjct: 241 DVNGGMLIH 249 >E8TQ66.1 E8TQ66_ALIDB Short-chain dehydrogenase/reductase SDR Length = 249 Score = 362 bits (930), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 191/249 (76%), Positives = 219/249 (87%) Query: 1 MLLKDKVAVITGGAGINGLGYATARLMAEQGARVVVLDLAQADPAAAAARIGSQHLGLVA 60 MLLKDKVAVITGGAGINGLG+ATAR+MAEQGARV +LDLA ADP AAAAR+G H+G+VA Sbjct: 1 MLLKDKVAVITGGAGINGLGFATARMMAEQGARVAILDLAAADPQAAAARLGDGHMGVVA 60 Query: 61 DVTDKASCDTAAAAILQQFGRIDILVNNAGITQPVKTLEITGADYDRILDVSLRGTLYMS 120 +VTDKASC+ AAAA+ ++GRIDILVNNAG+TQP K L+ITGADYDRILDVSLRGTLY S Sbjct: 61 NVTDKASCEAAAAAVQARYGRIDILVNNAGVTQPAKFLDITGADYDRILDVSLRGTLYAS 120 Query: 121 QAVLPAMRAQQNGSIICISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREFGPEGIRV 180 QAVLPAM AQQ+G+I+CISSVSAQRGGGILGGPHYSAAKAGVLGLARAMARE+G IRV Sbjct: 121 QAVLPAMLAQQSGAIVCISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREYGGSNIRV 180 Query: 181 NSITPGLIGTDIIKGKLTEEKKAEIAETIPLARLGRADDIGGACVFLGSDLSQYCTGITL 240 N +TPGLI TDI KGK+ ++K+ I + IPLAR+G D+ G VFL SDL++YCTG+TL Sbjct: 181 NCVTPGLIATDINKGKIPDDKRQGILDGIPLARIGEPADVAGCVVFLASDLAKYCTGVTL 240 Query: 241 DVNGGMLIH 249 DVNGGMLIH Sbjct: 241 DVNGGMLIH 249 >Q46RW1.1 Q46RW1_CUPPJ NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR Length = 249 Score = 336 bits (861), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 166/249 (66%), Positives = 204/249 (81%) Query: 1 MLLKDKVAVITGGAGINGLGYATARLMAEQGARVVVLDLAQADPAAAAARIGSQHLGLVA 60 ML+++KV ++TG A G+G ATAR ++ QGA VV+LDL + +AAA +G +HLGL Sbjct: 1 MLVENKVIIVTGAASPRGIGKATARALSAQGAHVVILDLKLEEAQSAAAELGPRHLGLAC 60 Query: 61 DVTDKASCDTAAAAILQQFGRIDILVNNAGITQPVKTLEITGADYDRILDVSLRGTLYMS 120 DVTDKA+C+ AA A++++FGRID LVNNAGITQP++TL+I A++D ++DV+LRGTLYMS Sbjct: 61 DVTDKAACERAALAVVERFGRIDGLVNNAGITQPLRTLDIQAANFDAVVDVNLRGTLYMS 120 Query: 121 QAVLPAMRAQQNGSIICISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREFGPEGIRV 180 QAVLP M+ Q+ GSI+C+SSVSAQRGGGI GGPHYSAAKAGVLGLARAMAREFG +GIRV Sbjct: 121 QAVLPQMKEQKRGSIVCMSSVSAQRGGGIFGGPHYSAAKAGVLGLARAMAREFGGDGIRV 180 Query: 181 NSITPGLIGTDIIKGKLTEEKKAEIAETIPLARLGRADDIGGACVFLGSDLSQYCTGITL 240 NSITPGLI TDI KLT + +A+I + IPL RLG A D+ AC+FL SDLS Y TGITL Sbjct: 181 NSITPGLIQTDITGDKLTADMRADIIKGIPLGRLGDAGDVANACLFLASDLSSYLTGITL 240 Query: 241 DVNGGMLIH 249 DVNGGMLIH Sbjct: 241 DVNGGMLIH 249 >D5WL89.1 D5WL89_BURSC Short-chain dehydrogenase/reductase SDR Length = 249 Score = 333 bits (854), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 170/249 (68%), Positives = 198/249 (79%) Query: 1 MLLKDKVAVITGGAGINGLGYATARLMAEQGARVVVLDLAQADPAAAAARIGSQHLGLVA 60 MLL+++ ++TG A G+G ATAR +A QGARVV+LDL + D +AAA +G++HLGL Sbjct: 1 MLLENRTIIVTGAASPRGIGKATARALAAQGARVVILDLRREDAQSAAADLGAKHLGLAC 60 Query: 61 DVTDKASCDTAAAAILQQFGRIDILVNNAGITQPVKTLEITGADYDRILDVSLRGTLYMS 120 DVTDK +C AA LQ+FGRID LVNNAGITQPV+TLEI G D+D I+DV+LRGTLYMS Sbjct: 61 DVTDKDACIAAARETLQRFGRIDGLVNNAGITQPVRTLEIGGKDFDAIVDVNLRGTLYMS 120 Query: 121 QAVLPAMRAQQNGSIICISSVSAQRGGGILGGPHYSAAKAGVLGLARAMAREFGPEGIRV 180 QAVLPAM+ Q GSI+C+SSVSAQRGGGI GGPHYSAAKAGVLGLA+AMAREFG IRV Sbjct: 121 QAVLPAMKEQNGGSIVCMSSVSAQRGGGIFGGPHYSAAKAGVLGLAKAMAREFGANHIRV 180 Query: 181 NSITPGLIGTDIIKGKLTEEKKAEIAETIPLARLGRADDIGGACVFLGSDLSQYCTGITL 240 NSITPGLI TDI KLT + +I + IPL RLG A D+ AC+FL SDLS Y TGITL Sbjct: 181 NSITPGLIHTDITGDKLTPAMRDDIIKGIPLGRLGDAADVANACLFLLSDLSSYLTGITL 240 Query: 241 DVNGGMLIH 249 DVNGGMLIH Sbjct: 241 DVNGGMLIH 249