BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0419.p (222 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J1M5.1 D8J1M5_HERSS HAD superfamily haloalkanoic acid dehaloge... 467 e-130 B9JK30.1 B9JK30_AGRRK Haloacid dehalogenase, type II 332 2e-89 Q6W115.1 Q6W115_RHISN Putative hydrolase 330 1e-88 Q12HG9.1 Q12HG9_POLSJ Haloacid dehalogenase, type II 330 1e-88 B5S5B9.1 B5S5B9_RALSO Putative hydrolase protein 326 1e-87 A3S097.1 A3S097_RALSO Probable 2-haloacid halidohydrolase IVa 326 1e-87 E0K798.1 E0K798_RHIME Haloacid dehalogenase, type II 325 2e-87 F0Q5Q1.1 F0Q5Q1_ACIAP Haloacid dehalogenase, type II 325 4e-87 D8N168.1 D8N168_RALSO 2-haloacid halidohydrolase type II EC=3.8.1.2 324 5e-87 D8P4U1.1 D8P4U1_RALSO 2-haloacid halidohydrolase type II EC=3.8.1.2 323 8e-87 >D8J1M5.1 D8J1M5_HERSS HAD superfamily haloalkanoic acid dehalogenase protein EC=3.8.1.2 Length = 222 Score = 467 bits (1202), Expect = e-130, Method: Compositional matrix adjust. Identities = 221/222 (99%), Positives = 221/222 (99%) Query: 1 MSTFKPKFITFDCYGTLTRFQMSETAQKIYADRVSAEDMPFFLRQFAAYRLDEVLDQWKP 60 MSTFKPKFITFDCYGTLTRFQMSETAQKIYADRVSAEDMPFFLRQFAAYRLDEVLDQWKP Sbjct: 1 MSTFKPKFITFDCYGTLTRFQMSETAQKIYADRVSAEDMPFFLRQFAAYRLDEVLDQWKP 60 Query: 61 YEQVCKNAITRTCARWGIQTNDEETGAFYKAVPTWGPHADVPAGLSKVAKEFPLVIFSNA 120 YEQVCKNAITRTCARWGIQTNDEETGAFYKAVPTWGPHADVPAGLSKVAKEFPLVIFSNA Sbjct: 61 YEQVCKNAITRTCARWGIQTNDEETGAFYKAVPTWGPHADVPAGLSKVAKEFPLVIFSNA 120 Query: 121 DDSQIMHNVEQLGAPFHKVFTAQQAQAYKPRLRAFEYMLDNLNCNPEDVLHVSSSLRYDL 180 DDSQIMHNVEQLGA FHKVFTAQQAQAYKPRLRAFEYMLDNLNCNPEDVLHVSSSLRYDL Sbjct: 121 DDSQIMHNVEQLGAAFHKVFTAQQAQAYKPRLRAFEYMLDNLNCNPEDVLHVSSSLRYDL 180 Query: 181 MPAADMGIKNKVFVARGHEPSTPFYGYTEIKDISGLPGVLGL 222 MPAADMGIKNKVFVARGHEPSTPFYGYTEIKDISGLPGVLGL Sbjct: 181 MPAADMGIKNKVFVARGHEPSTPFYGYTEIKDISGLPGVLGL 222 >B9JK30.1 B9JK30_AGRRK Haloacid dehalogenase, type II Length = 222 Score = 332 bits (852), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 151/222 (68%), Positives = 180/222 (81%) Query: 1 MSTFKPKFITFDCYGTLTRFQMSETAQKIYADRVSAEDMPFFLRQFAAYRLDEVLDQWKP 60 M+TF+PK+ITFDCYGTLT FQM+E AQKIY +++ M F++ FAAYRLDE+L WKP Sbjct: 1 MTTFRPKYITFDCYGTLTNFQMAEAAQKIYGEQLDQPRMAQFIKNFAAYRLDEILGDWKP 60 Query: 61 YEQVCKNAITRTCARWGIQTNDEETGAFYKAVPTWGPHADVPAGLSKVAKEFPLVIFSNA 120 Y +V NA+ RTC + G+ DE+ + Y+ VP+WGPHADVPAGL+KVAKE PLVI SNA Sbjct: 61 YNEVLHNAVERTCRKNGVTFRDEDARSIYETVPSWGPHADVPAGLAKVAKEIPLVILSNA 120 Query: 121 DDSQIMHNVEQLGAPFHKVFTAQQAQAYKPRLRAFEYMLDNLNCNPEDVLHVSSSLRYDL 180 + QIMHNVE+LGAPFH VFTAQQA AYKPR +AFEYM D L CNPEDV+H SSS RYDL Sbjct: 121 MNEQIMHNVEKLGAPFHAVFTAQQANAYKPRFKAFEYMFDMLGCNPEDVMHCSSSFRYDL 180 Query: 181 MPAADMGIKNKVFVARGHEPSTPFYGYTEIKDISGLPGVLGL 222 M A D+GIK+KV+V RGHEP+ P+Y YTEIKDISGLPGV+GL Sbjct: 181 MSAYDLGIKHKVWVNRGHEPANPYYEYTEIKDISGLPGVVGL 222 >Q6W115.1 Q6W115_RHISN Putative hydrolase Length = 222 Score = 330 bits (845), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 150/222 (67%), Positives = 180/222 (81%) Query: 1 MSTFKPKFITFDCYGTLTRFQMSETAQKIYADRVSAEDMPFFLRQFAAYRLDEVLDQWKP 60 M++F+PK+ITFDCYGTLT FQM+E A+ +Y++++ M F+R FAAYRLDE+L WKP Sbjct: 1 MASFRPKYITFDCYGTLTNFQMAEAARDLYSEQLDEPRMQEFIRNFAAYRLDEILGDWKP 60 Query: 61 YEQVCKNAITRTCARWGIQTNDEETGAFYKAVPTWGPHADVPAGLSKVAKEFPLVIFSNA 120 Y +V N++ RTC R GI+ DE Y+ VP WGPHADVPAGL+KVAKE PLVI SNA Sbjct: 61 YAEVVHNSLERTCKRNGIKFRDEAARVVYERVPNWGPHADVPAGLAKVAKEIPLVILSNA 120 Query: 121 DDSQIMHNVEQLGAPFHKVFTAQQAQAYKPRLRAFEYMLDNLNCNPEDVLHVSSSLRYDL 180 +SQIM NVE+LGAPFH V+TA+QAQAYKPR +AFEYMLD L C PED+LH SSS RYDL Sbjct: 121 MNSQIMSNVEKLGAPFHAVYTAEQAQAYKPRFKAFEYMLDMLGCGPEDILHCSSSFRYDL 180 Query: 181 MPAADMGIKNKVFVARGHEPSTPFYGYTEIKDISGLPGVLGL 222 M A D+GIKNKV+V RGHEP+ P+YGYTEIKDISGLPGV+GL Sbjct: 181 MSAHDLGIKNKVWVNRGHEPANPYYGYTEIKDISGLPGVVGL 222 >Q12HG9.1 Q12HG9_POLSJ Haloacid dehalogenase, type II Length = 221 Score = 330 bits (845), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 149/220 (67%), Positives = 176/220 (80%) Query: 3 TFKPKFITFDCYGTLTRFQMSETAQKIYADRVSAEDMPFFLRQFAAYRLDEVLDQWKPYE 62 TF+PKFITFDCYGTLTRF+M + A++++ADR+ A M F+ F+AYR DEVL WKPY Sbjct: 2 TFRPKFITFDCYGTLTRFRMGDMAREMFADRIPAAQMELFVADFSAYRFDEVLGAWKPYA 61 Query: 63 QVCKNAITRTCARWGIQTNDEETGAFYKAVPTWGPHADVPAGLSKVAKEFPLVIFSNADD 122 V +NA+ RTC +W I+ D E A+Y AVPTWGPHADVPAGLS++A + PLVI SNA + Sbjct: 62 DVLRNALNRTCKKWNIKCTDAEGRAYYDAVPTWGPHADVPAGLSRIADKIPLVILSNASN 121 Query: 123 SQIMHNVEQLGAPFHKVFTAQQAQAYKPRLRAFEYMLDNLNCNPEDVLHVSSSLRYDLMP 182 QI NV++LGAPFH+VFTAQQAQAYKPRL+AFEYMLD L C PED+LHVSSSLRYDLM Sbjct: 122 DQIHKNVDKLGAPFHRVFTAQQAQAYKPRLQAFEYMLDQLGCGPEDILHVSSSLRYDLMS 181 Query: 183 AADMGIKNKVFVARGHEPSTPFYGYTEIKDISGLPGVLGL 222 A D+GIKNKVFV RGH P P Y Y EI+DI GLPGV+GL Sbjct: 182 ADDLGIKNKVFVNRGHGPGNPAYNYVEIQDIGGLPGVVGL 221 >B5S5B9.1 B5S5B9_RALSO Putative hydrolase protein Length = 221 Score = 326 bits (836), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 152/220 (69%), Positives = 174/220 (79%) Query: 3 TFKPKFITFDCYGTLTRFQMSETAQKIYADRVSAEDMPFFLRQFAAYRLDEVLDQWKPYE 62 TF+PK++TFDCYGTLTRF+M E ++++ADR+ A M F+ F AYR DEVL WKPYE Sbjct: 2 TFRPKYVTFDCYGTLTRFRMGELTRELFADRIPAAHMEPFIADFTAYRFDEVLGDWKPYE 61 Query: 63 QVCKNAITRTCARWGIQTNDEETGAFYKAVPTWGPHADVPAGLSKVAKEFPLVIFSNADD 122 V KNA+ R C +W IQ D + A+Y AVPTW PHADVPAGL+KVA+E PLVI SNA D Sbjct: 62 VVLKNAVRRLCKKWRIQYYDADGQAYYDAVPTWDPHADVPAGLAKVAREIPLVILSNASD 121 Query: 123 SQIMHNVEQLGAPFHKVFTAQQAQAYKPRLRAFEYMLDNLNCNPEDVLHVSSSLRYDLMP 182 QI NV LGAPFH+V+TAQQAQAYKPRL+AFEYMLD+L CNPEDVLHVSSSLRYDLM Sbjct: 122 DQIQKNVAMLGAPFHRVYTAQQAQAYKPRLKAFEYMLDSLGCNPEDVLHVSSSLRYDLMS 181 Query: 183 AADMGIKNKVFVARGHEPSTPFYGYTEIKDISGLPGVLGL 222 A D+GI NKVFV RGH P P Y YTEI+DI GLPGVLGL Sbjct: 182 ADDIGIVNKVFVNRGHGPGNPAYRYTEIQDIGGLPGVLGL 221 >A3S097.1 A3S097_RALSO Probable 2-haloacid halidohydrolase IVa Length = 221 Score = 326 bits (836), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 152/220 (69%), Positives = 174/220 (79%) Query: 3 TFKPKFITFDCYGTLTRFQMSETAQKIYADRVSAEDMPFFLRQFAAYRLDEVLDQWKPYE 62 TF+PK++TFDCYGTLTRF+M E ++++ADR+ A M F+ F AYR DEVL WKPYE Sbjct: 2 TFRPKYVTFDCYGTLTRFRMGELTRELFADRIPAAHMEPFIADFTAYRFDEVLGDWKPYE 61 Query: 63 QVCKNAITRTCARWGIQTNDEETGAFYKAVPTWGPHADVPAGLSKVAKEFPLVIFSNADD 122 V KNA+ R C +W IQ D + A+Y AVPTW PHADVPAGL+KVA+E PLVI SNA D Sbjct: 62 VVLKNAVRRLCKKWRIQYYDADGQAYYDAVPTWDPHADVPAGLAKVAREIPLVILSNASD 121 Query: 123 SQIMHNVEQLGAPFHKVFTAQQAQAYKPRLRAFEYMLDNLNCNPEDVLHVSSSLRYDLMP 182 QI NV LGAPFH+V+TAQQAQAYKPRL+AFEYMLD+L CNPEDVLHVSSSLRYDLM Sbjct: 122 DQIQKNVAMLGAPFHRVYTAQQAQAYKPRLKAFEYMLDSLGCNPEDVLHVSSSLRYDLMS 181 Query: 183 AADMGIKNKVFVARGHEPSTPFYGYTEIKDISGLPGVLGL 222 A D+GI NKVFV RGH P P Y YTEI+DI GLPGVLGL Sbjct: 182 ADDIGIVNKVFVNRGHGPGNPAYRYTEIQDIGGLPGVLGL 221 >E0K798.1 E0K798_RHIME Haloacid dehalogenase, type II Length = 222 Score = 325 bits (834), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 147/222 (66%), Positives = 178/222 (80%) Query: 1 MSTFKPKFITFDCYGTLTRFQMSETAQKIYADRVSAEDMPFFLRQFAAYRLDEVLDQWKP 60 MS F+PK+ITFDCYGTLT FQM+E A+ +Y++++ M F++ FAAYRLDE+L WKP Sbjct: 1 MSIFRPKYITFDCYGTLTNFQMAEAARDLYSEQLDEARMAEFIKNFAAYRLDEILGDWKP 60 Query: 61 YEQVCKNAITRTCARWGIQTNDEETGAFYKAVPTWGPHADVPAGLSKVAKEFPLVIFSNA 120 Y +V N++ RTC R GI+ +E Y+ VPTWGPHADVPAGL++VAKE PLVI SNA Sbjct: 61 YAEVVHNSLERTCKRNGIEFREEAARMVYERVPTWGPHADVPAGLARVAKEIPLVILSNA 120 Query: 121 DDSQIMHNVEQLGAPFHKVFTAQQAQAYKPRLRAFEYMLDNLNCNPEDVLHVSSSLRYDL 180 +SQIM NVE+LGAPFH V+TA+QAQAYKPR +AFEYMLD L C PED+LH SSS RYDL Sbjct: 121 MNSQIMSNVEKLGAPFHAVYTAEQAQAYKPRFKAFEYMLDMLGCGPEDILHCSSSFRYDL 180 Query: 181 MPAADMGIKNKVFVARGHEPSTPFYGYTEIKDISGLPGVLGL 222 M A D+GIKNKV+V RGHEP+ P+YGY EI DISGLPGV+GL Sbjct: 181 MSAHDLGIKNKVWVNRGHEPANPYYGYVEIADISGLPGVVGL 222 >F0Q5Q1.1 F0Q5Q1_ACIAP Haloacid dehalogenase, type II Length = 221 Score = 325 bits (832), Expect = 4e-87, Method: Compositional matrix adjust. Identities = 150/220 (68%), Positives = 175/220 (79%) Query: 3 TFKPKFITFDCYGTLTRFQMSETAQKIYADRVSAEDMPFFLRQFAAYRLDEVLDQWKPYE 62 TF+PK+ITFDCYGTLTRF+M E A++++ADRV A+ M F+ F AYR DEVL W+PYE Sbjct: 2 TFRPKYITFDCYGTLTRFRMGEMAREMFADRVPADRMEQFVADFTAYRFDEVLGDWQPYE 61 Query: 63 QVCKNAITRTCARWGIQTNDEETGAFYKAVPTWGPHADVPAGLSKVAKEFPLVIFSNADD 122 QV KNAI R C +W +Q D E +Y AVPTWGPHADVPAGL++VA+E PLVI SNA D Sbjct: 62 QVLKNAIRRLCRKWNLQYFDHEAQRYYDAVPTWGPHADVPAGLARVAREIPLVILSNASD 121 Query: 123 SQIMHNVEQLGAPFHKVFTAQQAQAYKPRLRAFEYMLDNLNCNPEDVLHVSSSLRYDLMP 182 QI NV+ LGAPFH+V+TAQ AQAYKPRL+AFE+M D+L CNPEDVLHVSSSLRYDLM Sbjct: 122 DQIHRNVDMLGAPFHRVYTAQMAQAYKPRLKAFEFMFDSLGCNPEDVLHVSSSLRYDLMS 181 Query: 183 AADMGIKNKVFVARGHEPSTPFYGYTEIKDISGLPGVLGL 222 A D+GI NKVFV RGH P P Y YTEI+DI GL GV+GL Sbjct: 182 ADDIGIVNKVFVNRGHGPGNPAYRYTEIQDIGGLAGVVGL 221 >D8N168.1 D8N168_RALSO 2-haloacid halidohydrolase type II EC=3.8.1.2 Length = 221 Score = 324 bits (831), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 151/220 (68%), Positives = 174/220 (79%) Query: 3 TFKPKFITFDCYGTLTRFQMSETAQKIYADRVSAEDMPFFLRQFAAYRLDEVLDQWKPYE 62 TF+PK++TFDCYGTLTRF+M E ++++ADR+ AE M F+ F AYR DEVL W+PYE Sbjct: 2 TFRPKYVTFDCYGTLTRFRMGELTRELFADRIPAEHMEPFIADFTAYRFDEVLGDWQPYE 61 Query: 63 QVCKNAITRTCARWGIQTNDEETGAFYKAVPTWGPHADVPAGLSKVAKEFPLVIFSNADD 122 V KNA+ R C +W IQ D + A+Y AVPTW PHADVPAGL+KVA+E PLVI SNA D Sbjct: 62 VVLKNAVRRLCKKWRIQYYDADGQAYYDAVPTWDPHADVPAGLAKVAREIPLVILSNAAD 121 Query: 123 SQIMHNVEQLGAPFHKVFTAQQAQAYKPRLRAFEYMLDNLNCNPEDVLHVSSSLRYDLMP 182 QI NV LGAPFH+V+TAQQAQAYKPRL+AFEYMLD+L CNPEDVLHVSSSLRYDLM Sbjct: 122 DQIQKNVAMLGAPFHRVYTAQQAQAYKPRLKAFEYMLDSLGCNPEDVLHVSSSLRYDLMS 181 Query: 183 AADMGIKNKVFVARGHEPSTPFYGYTEIKDISGLPGVLGL 222 A D+GI NKVFV RGH P P Y YTEI DI GLPGV+GL Sbjct: 182 ADDIGIVNKVFVNRGHGPGNPAYRYTEIPDIGGLPGVVGL 221 >D8P4U1.1 D8P4U1_RALSO 2-haloacid halidohydrolase type II EC=3.8.1.2 Length = 221 Score = 323 bits (829), Expect = 8e-87, Method: Compositional matrix adjust. Identities = 150/220 (68%), Positives = 174/220 (79%) Query: 3 TFKPKFITFDCYGTLTRFQMSETAQKIYADRVSAEDMPFFLRQFAAYRLDEVLDQWKPYE 62 TF+PK++TFDCYGTLTRF+M E ++++ADR+ A M F+ F AYR DEVL WKPYE Sbjct: 2 TFRPKYVTFDCYGTLTRFRMGELTRELFADRIPAAHMEPFIADFTAYRFDEVLGDWKPYE 61 Query: 63 QVCKNAITRTCARWGIQTNDEETGAFYKAVPTWGPHADVPAGLSKVAKEFPLVIFSNADD 122 V KNA+ R C +W IQ D + A+Y AVPTW PHADVPAGL+KVA+E PLVI SNA D Sbjct: 62 VVLKNAVRRLCKKWRIQYYDTDGQAYYDAVPTWDPHADVPAGLAKVAREIPLVILSNASD 121 Query: 123 SQIMHNVEQLGAPFHKVFTAQQAQAYKPRLRAFEYMLDNLNCNPEDVLHVSSSLRYDLMP 182 QI NV LGAPFH+V+TAQQAQAYKPRL+AFEYMLD+L CNPEDVLHVSSSLRYDLM Sbjct: 122 DQIQKNVAMLGAPFHRVYTAQQAQAYKPRLKAFEYMLDSLGCNPEDVLHVSSSLRYDLMS 181 Query: 183 AADMGIKNKVFVARGHEPSTPFYGYTEIKDISGLPGVLGL 222 A D+GI NKVFV RGH P P Y YTEI++I GLPGV+GL Sbjct: 182 ADDIGIVNKVFVNRGHGPGNPAYRYTEIQNIGGLPGVVGL 221