BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0049.p (637 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IX77.1 D8IX77_HERSS Phosphomethylpyrimidine synthase EC=4.-.-.- 1329 0.0 A6SUX7.1 THIC_JANMA Phosphomethylpyrimidine synthase EC=4.-.-.- 1234 0.0 A4G224.1 THIC_HERAR Phosphomethylpyrimidine synthase EC=4.-.-.- 1227 0.0 F1VWL4.1 F1VWL4_9BURK Thiamin biosynthesis protein ThiC 1201 0.0 C3X5F9.1 C3X5F9_OXAFO Phosphomethylpyrimidine synthase EC=4.-.-.- 1165 0.0 B2JJF7.1 THIC_BURP8 Phosphomethylpyrimidine synthase EC=4.-.-.- 1162 0.0 A6GPY6.1 A6GPY6_9BURK Phosphomethylpyrimidine synthase EC=4.-.-.- 1155 0.0 E1TCU8.1 E1TCU8_BURSG Phosphomethylpyrimidine synthase EC=4.-.-.- 1153 0.0 F0GGU4.1 F0GGU4_9BURK Thiamine biosynthesis protein ThiC 1152 0.0 B9BBK1.1 B9BBK1_9BURK Phosphomethylpyrimidine synthase EC=4.-.-.- 1152 0.0 >D8IX77.1 D8IX77_HERSS Phosphomethylpyrimidine synthase EC=4.-.-.- Length = 637 Score = 1329 bits (3439), Expect = 0.0, Method: Compositional matrix adjust. Identities = 636/637 (99%), Positives = 637/637 (100%) Query: 1 MNANPKFLSATATVDEAAVQPLPNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPP 60 MNANPKFLSATATVDEAA+QPLPNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPP Sbjct: 1 MNANPKFLSATATVDEAAIQPLPNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPP 60 Query: 61 IYVYDTSGPYTDPEVKIDIRAGLSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAEL 120 IYVYDTSGPYTDPEVKIDIRAGLSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAEL Sbjct: 61 IYVYDTSGPYTDPEVKIDIRAGLSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAEL 120 Query: 121 RFNLHRKPRRAKAGANVTQMHYARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNKL 180 RFNLHRKPRRAKAGANVTQMHYARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNKL Sbjct: 121 RFNLHRKPRRAKAGANVTQMHYARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNKL 180 Query: 181 ADLMGRQHPGQSFGASIPAEITPEFVRDEVARGRAIIPANINHPEVEPMIIGRNFLVKIN 240 ADLMGRQHPGQSFGASIPAEITPEFVRDEVARGRAIIPANINHPEVEPMIIGRNFLVKIN Sbjct: 181 ADLMGRQHPGQSFGASIPAEITPEFVRDEVARGRAIIPANINHPEVEPMIIGRNFLVKIN 240 Query: 241 ANIGNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPIGTVPIY 300 ANIGNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPIGTVPIY Sbjct: 241 ANIGNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPIGTVPIY 300 Query: 301 QALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGS 360 QALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGS Sbjct: 301 QALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGS 360 Query: 361 IMAKWCLAHHRESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELRTLG 420 IMAKWCLAHHRESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELRTLG Sbjct: 361 IMAKWCLAHHRESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELRTLG 420 Query: 421 ELTQIAWKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHIT 480 ELTQIAWKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHIT Sbjct: 421 ELTQIAWKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHIT 480 Query: 481 SGIGAAQIGWYGTAMLCYVTPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHPGAQIRD 540 SGIGAAQIGWYGTAMLCYVTPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHPGAQIRD Sbjct: 481 SGIGAAQIGWYGTAMLCYVTPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHPGAQIRD 540 Query: 541 NALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEV 600 NALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEV Sbjct: 541 NALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEV 600 Query: 601 RDYAAKEGISEIDALKQGMQVKSVEFVKMGAEIYSKQ 637 RDYAAKEGISEIDALKQGMQVKSVEFVKMGAEIYSKQ Sbjct: 601 RDYAAKEGISEIDALKQGMQVKSVEFVKMGAEIYSKQ 637 >A6SUX7.1 THIC_JANMA Phosphomethylpyrimidine synthase EC=4.-.-.- Length = 637 Score = 1234 bits (3192), Expect = 0.0, Method: Compositional matrix adjust. Identities = 581/637 (91%), Positives = 611/637 (95%) Query: 1 MNANPKFLSATATVDEAAVQPLPNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPP 60 MNANPKFLSATATVDEA++QPLPNSRKIY+ GSRPDIRVPMREI+Q+DT A FG EKNPP Sbjct: 1 MNANPKFLSATATVDEASIQPLPNSRKIYIEGSRPDIRVPMREITQSDTAASFGFEKNPP 60 Query: 61 IYVYDTSGPYTDPEVKIDIRAGLSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAEL 120 IYVYDTSGPYTDP KIDIR+GL TPRLPWILER+DTEELPGPTSEYG +RLNDP LAEL Sbjct: 61 IYVYDTSGPYTDPAAKIDIRSGLDTPRLPWILERNDTEELPGPTSEYGIERLNDPKLAEL 120 Query: 121 RFNLHRKPRRAKAGANVTQMHYARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNKL 180 RFNLHRKPRRA AG NV+QMHYAR+GIITPEMEF+AIREN+ R+ YLE+LK SGP G KL Sbjct: 121 RFNLHRKPRRALAGKNVSQMHYARQGIITPEMEFVAIRENMNRRAYLEELKKSGPKGEKL 180 Query: 181 ADLMGRQHPGQSFGASIPAEITPEFVRDEVARGRAIIPANINHPEVEPMIIGRNFLVKIN 240 A+LMGRQHPGQSFGA+IP EIT EFVR E+ARGRAIIPANINHPE+EPMIIGRNFLVKIN Sbjct: 181 AELMGRQHPGQSFGAAIPQEITAEFVRSEIARGRAIIPANINHPEIEPMIIGRNFLVKIN 240 Query: 241 ANIGNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPIGTVPIY 300 ANIGNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGK+IHETREWIIRNSPVPIGTVPIY Sbjct: 241 ANIGNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKHIHETREWIIRNSPVPIGTVPIY 300 Query: 301 QALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGS 360 QALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGV L+YVP+TAKRMTGIVSRGGS Sbjct: 301 QALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRMTGIVSRGGS 360 Query: 361 IMAKWCLAHHRESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELRTLG 420 IMAKWCLAHH+ESFLYEHFE+ICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGEL+TLG Sbjct: 361 IMAKWCLAHHKESFLYEHFEDICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLG 420 Query: 421 ELTQIAWKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHIT 480 ELTQIAWKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHIT Sbjct: 421 ELTQIAWKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHIT 480 Query: 481 SGIGAAQIGWYGTAMLCYVTPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHPGAQIRD 540 SGIGAAQIGWYGTAMLCYVTPKEHLGLPNK DVKDGIITYKIAAHAADLAKGH GAQIRD Sbjct: 481 SGIGAAQIGWYGTAMLCYVTPKEHLGLPNKVDVKDGIITYKIAAHAADLAKGHIGAQIRD 540 Query: 541 NALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEV 600 NALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEV Sbjct: 541 NALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEV 600 Query: 601 RDYAAKEGISEIDALKQGMQVKSVEFVKMGAEIYSKQ 637 RDYAAK+GI+EI ALK GM+VK++EFVK G+EIY KQ Sbjct: 601 RDYAAKQGITEIQALKAGMEVKAIEFVKSGSEIYQKQ 637 >A4G224.1 THIC_HERAR Phosphomethylpyrimidine synthase EC=4.-.-.- Length = 637 Score = 1227 bits (3175), Expect = 0.0, Method: Compositional matrix adjust. Identities = 578/637 (90%), Positives = 610/637 (95%) Query: 1 MNANPKFLSATATVDEAAVQPLPNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPP 60 MNANPKFLSATATVDEAA+QPLPNS KIY+ GSRPDIRVPMR+I+Q+DT A FG EKNP Sbjct: 1 MNANPKFLSATATVDEAAIQPLPNSTKIYIQGSRPDIRVPMRKITQSDTAASFGFEKNPA 60 Query: 61 IYVYDTSGPYTDPEVKIDIRAGLSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAEL 120 IYVYDTSGPYTDPE KIDIR+GL TPRLPWILER DTEELPGPTSEYG +RLNDP LAEL Sbjct: 61 IYVYDTSGPYTDPEAKIDIRSGLDTPRLPWILERQDTEELPGPTSEYGIERLNDPKLAEL 120 Query: 121 RFNLHRKPRRAKAGANVTQMHYARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNKL 180 RFNLHRKPRRA AG NV+QMHYAR+GIITPEMEF+AIREN+ R+ YLE+LK SGP G KL Sbjct: 121 RFNLHRKPRRALAGKNVSQMHYARQGIITPEMEFVAIRENMNRRAYLEELKQSGPKGEKL 180 Query: 181 ADLMGRQHPGQSFGASIPAEITPEFVRDEVARGRAIIPANINHPEVEPMIIGRNFLVKIN 240 A+LMGRQHPGQSFGA+IP EIT EFVR E+ARGRAIIPANINHPE+EPMIIGRNFLVKIN Sbjct: 181 AELMGRQHPGQSFGAAIPQEITAEFVRSEIARGRAIIPANINHPEIEPMIIGRNFLVKIN 240 Query: 241 ANIGNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPIGTVPIY 300 ANIGNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGK+IHETREWIIRNSPVPIGTVPIY Sbjct: 241 ANIGNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKHIHETREWIIRNSPVPIGTVPIY 300 Query: 301 QALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGS 360 QALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGV L+YVP+TAKRMTGIVSRGGS Sbjct: 301 QALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRMTGIVSRGGS 360 Query: 361 IMAKWCLAHHRESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELRTLG 420 IMAKWCLAHH+ESFLYEHFE+ICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGEL+TLG Sbjct: 361 IMAKWCLAHHKESFLYEHFEDICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLG 420 Query: 421 ELTQIAWKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHIT 480 ELTQIAWKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHIT Sbjct: 421 ELTQIAWKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHIT 480 Query: 481 SGIGAAQIGWYGTAMLCYVTPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHPGAQIRD 540 SGIGAAQIGWYGTAMLCYVTPKEHLGLPNK DVKDGIITYKIAAHAADLAKGH GAQIRD Sbjct: 481 SGIGAAQIGWYGTAMLCYVTPKEHLGLPNKVDVKDGIITYKIAAHAADLAKGHIGAQIRD 540 Query: 541 NALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEV 600 NALSKARFEFRW+DQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEV Sbjct: 541 NALSKARFEFRWDDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEV 600 Query: 601 RDYAAKEGISEIDALKQGMQVKSVEFVKMGAEIYSKQ 637 R+YAAK+GI+EI ALK+GM+VK++EFVK G+EIY KQ Sbjct: 601 REYAAKQGITEIQALKKGMEVKAIEFVKSGSEIYQKQ 637 >F1VWL4.1 F1VWL4_9BURK Thiamin biosynthesis protein ThiC Length = 646 Score = 1201 bits (3107), Expect = 0.0, Method: Compositional matrix adjust. Identities = 562/634 (88%), Positives = 603/634 (95%) Query: 4 NPKFLSATATVDEAAVQPLPNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPPIYV 63 N KF ++TA VDEAAVQPLPNS K YV GSRPD+RVPMR+I Q+DT A FG+EKNP IYV Sbjct: 13 NAKFDASTALVDEAAVQPLPNSSKFYVQGSRPDLRVPMRKIVQSDTAASFGAEKNPAIYV 72 Query: 64 YDTSGPYTDPEVKIDIRAGLSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAELRFN 123 YDTSGPYTDP+ IDIR+GLSTPRLPWILER+DTEEL GP+S YG +RLNDP LAELRFN Sbjct: 73 YDTSGPYTDPDAVIDIRSGLSTPRLPWILERNDTEELAGPSSAYGIERLNDPTLAELRFN 132 Query: 124 LHRKPRRAKAGANVTQMHYARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNKLADL 183 L R PRRA AG NVTQMHYAR+GIITPEME+++IREN+RR+EYL++LKASGPMGN+LADL Sbjct: 133 LKRTPRRALAGRNVTQMHYARQGIITPEMEYVSIRENMRRREYLDELKASGPMGNRLADL 192 Query: 184 MGRQHPGQSFGASIPAEITPEFVRDEVARGRAIIPANINHPEVEPMIIGRNFLVKINANI 243 MGRQHPGQSFGA+IPAEITPEFVR E+ARGRAIIPANINHPE+EPMIIGRNFLVKINANI Sbjct: 193 MGRQHPGQSFGAAIPAEITPEFVRSEIARGRAIIPANINHPEIEPMIIGRNFLVKINANI 252 Query: 244 GNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQAL 303 GNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGK+IHETREWI+RNSPVPIGTVP+YQAL Sbjct: 253 GNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKHIHETREWIVRNSPVPIGTVPLYQAL 312 Query: 304 EKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGSIMA 363 EKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGV L+YVP+TAKR+TGIVSRGGSIMA Sbjct: 313 EKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMA 372 Query: 364 KWCLAHHRESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELRTLGELT 423 KWCLAHH ESFLY HF +IC+IMKAYDVSFSLGDGLRPGSI+DANDEAQL EL+TLGELT Sbjct: 373 KWCLAHHEESFLYTHFNDICDIMKAYDVSFSLGDGLRPGSIFDANDEAQLAELKTLGELT 432 Query: 424 QIAWKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHITSGI 483 QIAW+HDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHITSGI Sbjct: 433 QIAWQHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHITSGI 492 Query: 484 GAAQIGWYGTAMLCYVTPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHPGAQIRDNAL 543 GAAQIGWYGTAMLCYVTPKEHLGLPNK DVKDGIITYKIAAHAADLAKGHP AQIRDNAL Sbjct: 493 GAAQIGWYGTAMLCYVTPKEHLGLPNKQDVKDGIITYKIAAHAADLAKGHPSAQIRDNAL 552 Query: 544 SKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEVRDY 603 SKARFEFRW+DQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEVRDY Sbjct: 553 SKARFEFRWDDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEVRDY 612 Query: 604 AAKEGISEIDALKQGMQVKSVEFVKMGAEIYSKQ 637 AAK+GIS+I ALKQGM+VK++EFVK GAE+Y KQ Sbjct: 613 AAKQGISDIAALKQGMEVKAIEFVKSGAELYRKQ 646 >C3X5F9.1 C3X5F9_OXAFO Phosphomethylpyrimidine synthase EC=4.-.-.- Length = 637 Score = 1165 bits (3015), Expect = 0.0, Method: Compositional matrix adjust. Identities = 544/637 (85%), Positives = 592/637 (92%) Query: 1 MNANPKFLSATATVDEAAVQPLPNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPP 60 MNANPKFLSATA VDEAAVQP PNSRKIYV GSRPDIRVPMREI+ +DTP MFGSEKNPP Sbjct: 1 MNANPKFLSATAKVDEAAVQPFPNSRKIYVQGSRPDIRVPMREITLSDTPVMFGSEKNPP 60 Query: 61 IYVYDTSGPYTDPEVKIDIRAGLSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAEL 120 IYVYDTSGPYTDP+ KIDIR+GL R PWILERDDTEEL GPTS YG++RLNDP+L EL Sbjct: 61 IYVYDTSGPYTDPDAKIDIRSGLPPIRTPWILERDDTEELDGPTSAYGRERLNDPSLDEL 120 Query: 121 RFNLHRKPRRAKAGANVTQMHYARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNKL 180 RFNL RKPRRAK GA +TQM YARRGI+TPEMEF+AIRENLRRKEYLE LKA+GP G K+ Sbjct: 121 RFNLTRKPRRAKKGAKITQMEYARRGIVTPEMEFVAIRENLRRKEYLESLKAAGPTGEKM 180 Query: 181 ADLMGRQHPGQSFGASIPAEITPEFVRDEVARGRAIIPANINHPEVEPMIIGRNFLVKIN 240 A +M RQHPGQSFGASIPAEITPEFVRDE+ARGRAIIPANINHPEVEPMIIGRNFLVKIN Sbjct: 181 AKMMMRQHPGQSFGASIPAEITPEFVRDEIARGRAIIPANINHPEVEPMIIGRNFLVKIN 240 Query: 241 ANIGNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPIGTVPIY 300 ANIGNSA++S I EEVEKMTWAIRWGGDNVMDLSTGK+IHETREWI+RNSPVPIGTVP+Y Sbjct: 241 ANIGNSALSSGIAEEVEKMTWAIRWGGDNVMDLSTGKHIHETREWIVRNSPVPIGTVPMY 300 Query: 301 QALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGGS 360 QALEKV+G AE+LTWE++RDTLIEQAEQGVDYFTIHAG+ L++VP TA+RMTGIVSRGGS Sbjct: 301 QALEKVDGVAENLTWEVYRDTLIEQAEQGVDYFTIHAGLLLRHVPTTAERMTGIVSRGGS 360 Query: 361 IMAKWCLAHHRESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELRTLG 420 I+AKWCLAHH ESFLY HFEEICEI+ YDV+ SLGDGLRPGSIYDANDEAQLGEL LG Sbjct: 361 IIAKWCLAHHTESFLYTHFEEICEILAQYDVAVSLGDGLRPGSIYDANDEAQLGELAVLG 420 Query: 421 ELTQIAWKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHIT 480 ELT+IAWKH VQV+IEGPGHVPMH+IKENMD+QLEQCHEAPFYTLGPL TDIAPGYDHIT Sbjct: 421 ELTEIAWKHGVQVLIEGPGHVPMHMIKENMDIQLEQCHEAPFYTLGPLVTDIAPGYDHIT 480 Query: 481 SGIGAAQIGWYGTAMLCYVTPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHPGAQIRD 540 S +GAA IGWYGTAMLCYVTPKEHLGLPNK DVK+GII YK+AAHAADLAKGHPGAQIRD Sbjct: 481 SAMGAAMIGWYGTAMLCYVTPKEHLGLPNKDDVKEGIIVYKLAAHAADLAKGHPGAQIRD 540 Query: 541 NALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQEV 600 NA+SKARFEFRWEDQFNIGLDPD+AR+FHD+TLPKDSAKVAHFCSMCGP FCSMKITQEV Sbjct: 541 NAMSKARFEFRWEDQFNIGLDPDRARQFHDDTLPKDSAKVAHFCSMCGPKFCSMKITQEV 600 Query: 601 RDYAAKEGISEIDALKQGMQVKSVEFVKMGAEIYSKQ 637 RDYAAK+GISE+ ALK+GM+ +SVEF+K G+EIY KQ Sbjct: 601 RDYAAKKGISEVQALKEGMEERSVEFIKTGSEIYHKQ 637 >B2JJF7.1 THIC_BURP8 Phosphomethylpyrimidine synthase EC=4.-.-.- Length = 643 Score = 1162 bits (3005), Expect = 0.0, Method: Compositional matrix adjust. Identities = 557/643 (86%), Positives = 591/643 (91%), Gaps = 6/643 (0%) Query: 1 MNANPKFLSATATVDEAAVQPLPNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPP 60 MNANPKF+SA A VDEAAV PLPNSRK+YVTGS+PDIRVPMREI+QADTP FG EKNPP Sbjct: 1 MNANPKFISANAHVDEAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTGFGGEKNPP 60 Query: 61 IYVYDTSGPYTDPEVKIDIRAGLSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAEL 120 IYVYDTSGPYTDP+ KIDIRAGL R WI R DTE L G +SEYG++R DPA AEL Sbjct: 61 IYVYDTSGPYTDPDAKIDIRAGLPALRQRWIEARGDTESLQGLSSEYGRERAADPATAEL 120 Query: 121 RF-NLHRKPRRAKAGANVTQMHYARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNK 179 RF LHR PRRA+ G NV+QMHYA++GIITPEME+IAIREN RR EYLE LKASGP G K Sbjct: 121 RFPGLHRTPRRAQPGKNVSQMHYAKQGIITPEMEYIAIRENQRRAEYLESLKASGPNGAK 180 Query: 180 LADLMGRQHPGQSFGASIPA-----EITPEFVRDEVARGRAIIPANINHPEVEPMIIGRN 234 LA +MGRQHPGQ+FGA+ EITPEFVR+EVARGRAIIPANINHPE EPMIIGRN Sbjct: 181 LAAMMGRQHPGQAFGATAFGPNGLQEITPEFVREEVARGRAIIPANINHPESEPMIIGRN 240 Query: 235 FLVKINANIGNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPI 294 FLVKINANIGNSAVTSSIGEEV+KMTWAIRWGGD VMDLSTGK+IHETREWIIRNSPVPI Sbjct: 241 FLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPI 300 Query: 295 GTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGI 354 GTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTA RMTGI Sbjct: 301 GTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGI 360 Query: 355 VSRGGSIMAKWCLAHHRESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLG 414 VSRGGSIMAKWCLAHH+ESFLYEHFE+ICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLG Sbjct: 361 VSRGGSIMAKWCLAHHKESFLYEHFEDICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLG 420 Query: 415 ELRTLGELTQIAWKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAP 474 EL+TLGELTQIAWKHDVQVMIEGPGHVPM LIKENMDLQLE C EAPFYTLGPLTTDIAP Sbjct: 421 ELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLEWCDEAPFYTLGPLTTDIAP 480 Query: 475 GYDHITSGIGAAQIGWYGTAMLCYVTPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHP 534 GYDHITSGIGAA IGW+GTAMLCYVTPKEHLGLPNK DVK GIITYK+AAHAADLAKGHP Sbjct: 481 GYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKTGIITYKLAAHAADLAKGHP 540 Query: 535 GAQIRDNALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSM 594 GAQ+RDNALSKARFEFRWEDQFN+GLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSM Sbjct: 541 GAQVRDNALSKARFEFRWEDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSM 600 Query: 595 KITQEVRDYAAKEGISEIDALKQGMQVKSVEFVKMGAEIYSKQ 637 KITQ+VRDYAAKEG+S+ DALK+GM+VK+VEF+K GAEIY +Q Sbjct: 601 KITQDVRDYAAKEGMSDADALKKGMEVKAVEFIKSGAEIYQRQ 643 >A6GPY6.1 A6GPY6_9BURK Phosphomethylpyrimidine synthase EC=4.-.-.- Length = 638 Score = 1155 bits (2988), Expect = 0.0, Method: Compositional matrix adjust. Identities = 544/637 (85%), Positives = 588/637 (92%), Gaps = 1/637 (0%) Query: 1 MNANPKFLSATATVDEAAVQPLPNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPP 60 M+ANP FL+ATA VDEAAV+PLPNSRK+YV GSRPDI+VPMREISQ DTP FG EKNPP Sbjct: 1 MSANPDFLAATAKVDEAAVKPLPNSRKVYVQGSRPDIQVPMREISQDDTPTSFGGEKNPP 60 Query: 61 IYVYDTSGPYTDPEVKIDIRAGLSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAEL 120 IYVYD SG YTDP KIDIR+GL R WI ER+DT+ L GP+SEYG +RLNDP L EL Sbjct: 61 IYVYDCSGIYTDPNAKIDIRSGLPAIRSAWIEERNDTDLLSGPSSEYGIERLNDPKLTEL 120 Query: 121 RFNLHRKPRRAKAGANVTQMHYARRGIITPEMEFIAIRENLRRKEYLEQLK-ASGPMGNK 179 RFNL RKPR+AKAG NV+QMHYAR+GIITPEME++AIRENLRR+EY+E LK A G +G K Sbjct: 121 RFNLQRKPRKAKAGKNVSQMHYARQGIITPEMEYVAIRENLRRQEYIESLKHAGGKIGAK 180 Query: 180 LADLMGRQHPGQSFGASIPAEITPEFVRDEVARGRAIIPANINHPEVEPMIIGRNFLVKI 239 + DL+ RQHPGQSFGASIP +ITPEFVRDE+ARGRAIIPANINHPE+EPMIIGRNFLVKI Sbjct: 181 MVDLLTRQHPGQSFGASIPEQITPEFVRDEIARGRAIIPANINHPEIEPMIIGRNFLVKI 240 Query: 240 NANIGNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPIGTVPI 299 NANIGNSAV+SSIGEEVEKMTW+IRWGGD VMDLSTGK+IHETREWI+RNSPVPIGTVPI Sbjct: 241 NANIGNSAVSSSIGEEVEKMTWSIRWGGDTVMDLSTGKHIHETREWILRNSPVPIGTVPI 300 Query: 300 YQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGIVSRGG 359 YQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRL YVP+TA RMTGIVSRGG Sbjct: 301 YQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLAYVPMTASRMTGIVSRGG 360 Query: 360 SIMAKWCLAHHRESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELRTL 419 SIMAKWCLAHH+ESFLYEHFE+ICEIMKAYDVSFSLGDGLRPGSI+DANDEAQL ELRTL Sbjct: 361 SIMAKWCLAHHKESFLYEHFEDICEIMKAYDVSFSLGDGLRPGSIWDANDEAQLSELRTL 420 Query: 420 GELTQIAWKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAPGYDHI 479 GELTQIAWKHDVQVMIEGPGHVPM LIKENMD+QL++CHEAPFYTLGPLTTDIAPGYDHI Sbjct: 421 GELTQIAWKHDVQVMIEGPGHVPMQLIKENMDIQLKECHEAPFYTLGPLTTDIAPGYDHI 480 Query: 480 TSGIGAAQIGWYGTAMLCYVTPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHPGAQIR 539 TSGIGAAQIGWYG AMLCYVTPKEHLGLPNK DVKDGIITYKIAAHAADLAKGHPGAQIR Sbjct: 481 TSGIGAAQIGWYGCAMLCYVTPKEHLGLPNKKDVKDGIITYKIAAHAADLAKGHPGAQIR 540 Query: 540 DNALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQE 599 DNALSKARFEFRW+DQFN+GLDPD AREFHDETLPK S KVAHFCSMCGPHFCSMKITQ+ Sbjct: 541 DNALSKARFEFRWDDQFNLGLDPDTAREFHDETLPKQSMKVAHFCSMCGPHFCSMKITQD 600 Query: 600 VRDYAAKEGISEIDALKQGMQVKSVEFVKMGAEIYSK 636 VR+YA K G+SE DAL +GM+ KS+EF+K G+EIY K Sbjct: 601 VREYAEKLGVSEKDALSKGMEEKSIEFIKKGSEIYHK 637 >E1TCU8.1 E1TCU8_BURSG Phosphomethylpyrimidine synthase EC=4.-.-.- Length = 643 Score = 1153 bits (2982), Expect = 0.0, Method: Compositional matrix adjust. Identities = 551/643 (85%), Positives = 589/643 (91%), Gaps = 6/643 (0%) Query: 1 MNANPKFLSATATVDEAAVQPLPNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPP 60 MNANPKFLSA A VDEAAV PLPNSRK+YVTGSRPDIRVPMREI+QADTP FG EKNPP Sbjct: 1 MNANPKFLSADAHVDEAAVAPLPNSRKVYVTGSRPDIRVPMREITQADTPDSFGGEKNPP 60 Query: 61 IYVYDTSGPYTDPEVKIDIRAGLSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAEL 120 +YVYDTSGPY+DP+ KIDIRAGL R WI ER DTE L G TSEYG++R DPA AEL Sbjct: 61 VYVYDTSGPYSDPDAKIDIRAGLPALRQRWIEERGDTEALTGLTSEYGRERAADPATAEL 120 Query: 121 RFN-LHRKPRRAKAGANVTQMHYARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNK 179 RF LHR PRRA G NV+QMHYAR+GIITPEME+IAIREN RR EYLE LK SGP G K Sbjct: 121 RFQGLHRTPRRALPGKNVSQMHYARKGIITPEMEYIAIRENQRRAEYLESLKKSGPNGEK 180 Query: 180 LADLMGRQHPGQSFGASI-----PAEITPEFVRDEVARGRAIIPANINHPEVEPMIIGRN 234 LA +MGRQHPGQ+FGAS EITPEFVR+EVARGRAIIP NINHPE EPMIIGRN Sbjct: 181 LAAMMGRQHPGQAFGASAFGPNGVTEITPEFVREEVARGRAIIPNNINHPESEPMIIGRN 240 Query: 235 FLVKINANIGNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPI 294 FLVK+NANIGNSAVTSSIGEEV+KMTWAIRWGGD VMDLSTGK+IHETREWIIRNSPVPI Sbjct: 241 FLVKVNANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPI 300 Query: 295 GTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGI 354 GTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGI Sbjct: 301 GTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGI 360 Query: 355 VSRGGSIMAKWCLAHHRESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLG 414 VSRGGSIMAKWCLAHH+ESFLYEHFE+ICEIMKAYDV+FSLGDGLRPGSIYDANDEAQLG Sbjct: 361 VSRGGSIMAKWCLAHHKESFLYEHFEDICEIMKAYDVAFSLGDGLRPGSIYDANDEAQLG 420 Query: 415 ELRTLGELTQIAWKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAP 474 EL+TLGELTQIAWKHDVQ MIEGPGHVPM LIKENMDLQLE C EAPFYTLGPLTTDIAP Sbjct: 421 ELKTLGELTQIAWKHDVQTMIEGPGHVPMQLIKENMDLQLEWCDEAPFYTLGPLTTDIAP 480 Query: 475 GYDHITSGIGAAQIGWYGTAMLCYVTPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHP 534 GYDHITSGIGAA IGW+GTAMLCYVTPKEHLGLPNK DVK GIITYK+AAHAADLAKGHP Sbjct: 481 GYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKTGIITYKLAAHAADLAKGHP 540 Query: 535 GAQIRDNALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSM 594 GAQ+RDNALSKARFEFRWEDQFN+GLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSM Sbjct: 541 GAQVRDNALSKARFEFRWEDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSM 600 Query: 595 KITQEVRDYAAKEGISEIDALKQGMQVKSVEFVKMGAEIYSKQ 637 KITQ+VR++AA++G+++ +ALK+GM+VKS+EF+K GAEIY +Q Sbjct: 601 KITQDVREFAAQQGVTDDEALKKGMEVKSIEFMKKGAEIYQRQ 643 >F0GGU4.1 F0GGU4_9BURK Thiamine biosynthesis protein ThiC Length = 643 Score = 1152 bits (2981), Expect = 0.0, Method: Compositional matrix adjust. Identities = 555/643 (86%), Positives = 591/643 (91%), Gaps = 6/643 (0%) Query: 1 MNANPKFLSATATVDEAAVQPLPNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPP 60 MNANPKFLSA A VD AA+ PLPNSRKIYVTGS+PDIRVPMREI+QADTP FG EKNPP Sbjct: 1 MNANPKFLSADAHVDAAAIAPLPNSRKIYVTGSQPDIRVPMREITQADTPTGFGGEKNPP 60 Query: 61 IYVYDTSGPYTDPEVKIDIRAGLSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAEL 120 +YVYDTSGPYTDP+ KIDIRAGL R WI R DTE LPG +S+YG++R DP A+L Sbjct: 61 VYVYDTSGPYTDPDAKIDIRAGLPALRQRWIEARGDTETLPGLSSQYGRERAADPVTADL 120 Query: 121 RF-NLHRKPRRAKAGANVTQMHYARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNK 179 RF LHR PRRA+AG NVTQMHYAR+GIITPEMEFIAIREN RR EYLE LKASGP G K Sbjct: 121 RFPGLHRNPRRAQAGRNVTQMHYARQGIITPEMEFIAIRENQRRAEYLESLKASGPNGAK 180 Query: 180 LADLMGRQHPGQSFGASI-----PAEITPEFVRDEVARGRAIIPANINHPEVEPMIIGRN 234 LA +MGRQHPGQ+FGA+ P EITPEFVR EVA GRAIIPANINHPE EPMIIGRN Sbjct: 181 LAAMMGRQHPGQAFGAAAFGANAPTEITPEFVRSEVASGRAIIPANINHPESEPMIIGRN 240 Query: 235 FLVKINANIGNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPI 294 FLVKINANIGNSAVTSSIGEEV+KMTWAIRWGGD VMDLSTGK+IHETREWIIRNSPVPI Sbjct: 241 FLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPI 300 Query: 295 GTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGI 354 GTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTA RMTGI Sbjct: 301 GTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGI 360 Query: 355 VSRGGSIMAKWCLAHHRESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLG 414 VSRGGSIMAKWCLAHH+ESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLG Sbjct: 361 VSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLG 420 Query: 415 ELRTLGELTQIAWKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAP 474 EL+TLGELTQIAWKHDVQVMIEGPGHVPM LIKENMDLQL+ C EAPFYTLGPLTTDIAP Sbjct: 421 ELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAP 480 Query: 475 GYDHITSGIGAAQIGWYGTAMLCYVTPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHP 534 GYDHITSGIGAA IGW+GTAMLCYVTPKEHLGLPNK DVK+GIITYK+AAHAADLAKGHP Sbjct: 481 GYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHP 540 Query: 535 GAQIRDNALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSM 594 GAQ+RDNALSKARFEFRWEDQFN+GLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSM Sbjct: 541 GAQVRDNALSKARFEFRWEDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSM 600 Query: 595 KITQEVRDYAAKEGISEIDALKQGMQVKSVEFVKMGAEIYSKQ 637 KITQ+VR++AA++G+SE DALK+GM+VK+VEFVK G+EIY +Q Sbjct: 601 KITQDVREFAAQQGVSETDALKKGMEVKAVEFVKSGSEIYHRQ 643 >B9BBK1.1 B9BBK1_9BURK Phosphomethylpyrimidine synthase EC=4.-.-.- Length = 643 Score = 1152 bits (2980), Expect = 0.0, Method: Compositional matrix adjust. Identities = 557/643 (86%), Positives = 595/643 (92%), Gaps = 6/643 (0%) Query: 1 MNANPKFLSATATVDEAAVQPLPNSRKIYVTGSRPDIRVPMREISQADTPAMFGSEKNPP 60 MNANPKFLSA A VD AAV PLPNSRK+YVTGS+PDIRVPMREI+QADTP FG EKNPP Sbjct: 1 MNANPKFLSADAHVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTGFGGEKNPP 60 Query: 61 IYVYDTSGPYTDPEVKIDIRAGLSTPRLPWILERDDTEELPGPTSEYGQQRLNDPALAEL 120 IYVYDTSGPYTDP+ KIDIRAGL R WI R DTE LPG +S+YG++R DPA A+L Sbjct: 61 IYVYDTSGPYTDPDAKIDIRAGLPALRQRWIEARGDTETLPGLSSQYGRERAADPATADL 120 Query: 121 RF-NLHRKPRRAKAGANVTQMHYARRGIITPEMEFIAIRENLRRKEYLEQLKASGPMGNK 179 RF LHR PRRA+AG NVTQMHYAR+GIITPEMEFIAIREN RR EYLE LKASGP G K Sbjct: 121 RFPGLHRNPRRARAGKNVTQMHYARQGIITPEMEFIAIRENQRRAEYLESLKASGPNGAK 180 Query: 180 LADLMGRQHPGQSFGASI-----PAEITPEFVRDEVARGRAIIPANINHPEVEPMIIGRN 234 LA +MGRQHPGQ+FGA+ P+EITPEFVRDEVARGRAIIPANINHPE EPMIIGRN Sbjct: 181 LAAMMGRQHPGQAFGAAAFGGNAPSEITPEFVRDEVARGRAIIPANINHPESEPMIIGRN 240 Query: 235 FLVKINANIGNSAVTSSIGEEVEKMTWAIRWGGDNVMDLSTGKNIHETREWIIRNSPVPI 294 FLVKINANIGNSAVTSSIGEEV+KMTWAIRWGGD VMDLSTGK+IHETREWIIRNSPVPI Sbjct: 241 FLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPI 300 Query: 295 GTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTAKRMTGI 354 GTVPIYQALEKVNGKAE+LTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTA RMTGI Sbjct: 301 GTVPIYQALEKVNGKAEELTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGI 360 Query: 355 VSRGGSIMAKWCLAHHRESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLG 414 VSRGGSIMAKWCLAHH+ESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLG Sbjct: 361 VSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLG 420 Query: 415 ELRTLGELTQIAWKHDVQVMIEGPGHVPMHLIKENMDLQLEQCHEAPFYTLGPLTTDIAP 474 EL+TLGELTQIAWKHDVQVMIEGPGHVPM LIKENMDLQL+ C EAPFYTLGPLTTDIAP Sbjct: 421 ELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAP 480 Query: 475 GYDHITSGIGAAQIGWYGTAMLCYVTPKEHLGLPNKTDVKDGIITYKIAAHAADLAKGHP 534 GYDHITSGIGAA IGW+GTAMLCYVTPKEHLGLPNK DVK+GIITYK+AAHAADLAKGHP Sbjct: 481 GYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHP 540 Query: 535 GAQIRDNALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSM 594 GAQ+RDNALSKARFEFRWEDQFN+GLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSM Sbjct: 541 GAQVRDNALSKARFEFRWEDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSM 600 Query: 595 KITQEVRDYAAKEGISEIDALKQGMQVKSVEFVKMGAEIYSKQ 637 KITQ+VR++AA++G+SE DAL++GM+VK+VEFVK G+EIY +Q Sbjct: 601 KITQDVREFAAQQGVSEADALQKGMEVKAVEFVKSGSEIYHRQ 643