BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0099.p (238 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J1W1.1 D8J1W1_HERSS Xanthine dehydrogenase (Subunit B) protein... 488 e-136 A6SV99.1 A6SV99_JANMA Xanthine dehydrogenase, subunit B EC=1.17.1.4 382 e-104 Q46YJ5.1 Q46YJ5_CUPPJ Xanthine oxidase EC=1.17.3.2 371 e-101 B3R3T3.1 B3R3T3_CUPTR XANTHINE DEHYDROGENASE (SUBUNIT B) OXIDORE... 368 e-100 E0XWN7.1 E0XWN7_9PROT Xanthine dehydrogenase, molybdopterin-bind... 358 5e-97 F1W100.1 F1W100_9BURK Xanthine dehydrogenase, molybdenum binding... 355 4e-96 Q0KCW3.1 Q0KCW3_CUPNH Xanthine dehydrogenase, subunit B EC=1.17.1.4 351 4e-95 D5NI79.1 D5NI79_9BURK Xanthine dehydrogenase, molybdopterin bind... 351 5e-95 Q1LPZ8.1 Q1LPZ8_RALME Xanthine dehydrogenase, subunit B EC=1.17.1.4 348 3e-94 D8D0T9.1 D8D0T9_COMTE Xanthine dehydrogenase, molybdopterin bind... 348 3e-94 >D8J1W1.1 D8J1W1_HERSS Xanthine dehydrogenase (Subunit B) protein EC=1.17.1.4 Length = 789 Score = 488 bits (1255), Expect = e-136, Method: Compositional matrix adjust. Identities = 235/238 (98%), Positives = 236/238 (99%) Query: 1 LQIRTRLAQVAAPLLGVEPTAVRFADGRVMAGAQSMAFAELVMKAYLQRVQLWSDGFYST 60 LQ+RTRLAQVAA LLGVEPTAVRFADGRVMAGAQSMAFAELVMKAYLQRVQLWSDGFYST Sbjct: 552 LQVRTRLAQVAATLLGVEPTAVRFADGRVMAGAQSMAFAELVMKAYLQRVQLWSDGFYST 611 Query: 61 PKVHWDAKRMHGHPFFYFAYAAAVSEVVIDTLTGEWKLLQADLLYDAGQSLNPALDIGQV 120 PKVHWDAKRMHGHPFFYFAYAAAVSEVVIDTLTGEWKLLQADLLYDAGQSLNPALDIGQV Sbjct: 612 PKVHWDAKRMHGHPFFYFAYAAAVSEVVIDTLTGEWKLLQADLLYDAGQSLNPALDIGQV 671 Query: 121 EGGFIQGMGWLTTEELWWNKDGKLMTHAPSTYKIPAISDCPARLRTELFQNSNVSDTIHR 180 EGGFIQGMGWLTTEELWWNKDGKLMTHAPSTYKIPAISDCPARLRTELFQN NVSDTIHR Sbjct: 672 EGGFIQGMGWLTTEELWWNKDGKLMTHAPSTYKIPAISDCPARLRTELFQNRNVSDTIHR 731 Query: 181 SKAVGEPPLLLPFSVFLAIRDAVSAVGGHRVNPPLRAPATSEAILDAVDAVRAATASR 238 SKAVGEPPLLLPFSVFLAIRDAVSAVGGHRVNPPLRAPATSEAILDAVDAVRAATASR Sbjct: 732 SKAVGEPPLLLPFSVFLAIRDAVSAVGGHRVNPPLRAPATSEAILDAVDAVRAATASR 789 >A6SV99.1 A6SV99_JANMA Xanthine dehydrogenase, subunit B EC=1.17.1.4 Length = 785 Score = 382 bits (982), Expect = e-104, Method: Compositional matrix adjust. Identities = 184/234 (78%), Positives = 210/234 (89%) Query: 1 LQIRTRLAQVAAPLLGVEPTAVRFADGRVMAGAQSMAFAELVMKAYLQRVQLWSDGFYST 60 LQIR RLA +AA GV+ + FADG+V +G QS+AF ELVM+ YL RVQLWSDGFYST Sbjct: 550 LQIRDRLANLAAQRFGVDVATIGFADGKVSSGEQSIAFKELVMQGYLARVQLWSDGFYST 609 Query: 61 PKVHWDAKRMHGHPFFYFAYAAAVSEVVIDTLTGEWKLLQADLLYDAGQSLNPALDIGQV 120 P+VHW+AK M+GHPF+Y+AY AAV+EVVIDTLTGEWKLL+AD LYDAG++LNPA+D+GQV Sbjct: 610 PRVHWNAKTMNGHPFYYYAYGAAVAEVVIDTLTGEWKLLRADALYDAGEALNPAIDLGQV 669 Query: 121 EGGFIQGMGWLTTEELWWNKDGKLMTHAPSTYKIPAISDCPARLRTELFQNSNVSDTIHR 180 EGGFIQGMGWLTTEELWWNK+GKLMTHAPSTYKIPAISDCP R +LF+NSNV D+IHR Sbjct: 670 EGGFIQGMGWLTTEELWWNKEGKLMTHAPSTYKIPAISDCPPDFRVKLFKNSNVQDSIHR 729 Query: 181 SKAVGEPPLLLPFSVFLAIRDAVSAVGGHRVNPPLRAPATSEAILDAVDAVRAA 234 SKAVGEPPLLLPFSVF AIRDAV+AVG +R+NPPLRAPATSEAILDA+DAVRAA Sbjct: 730 SKAVGEPPLLLPFSVFFAIRDAVAAVGNNRINPPLRAPATSEAILDAIDAVRAA 783 >Q46YJ5.1 Q46YJ5_CUPPJ Xanthine oxidase EC=1.17.3.2 Length = 793 Score = 371 bits (952), Expect = e-101, Method: Compositional matrix adjust. Identities = 173/236 (73%), Positives = 197/236 (83%) Query: 2 QIRTRLAQVAAPLLGVEPTAVRFADGRVMAGAQSMAFAELVMKAYLQRVQLWSDGFYSTP 61 QIR RLA+ AA GV P +VRF D V+AG + F EL +AYL RVQLWSDGFY+TP Sbjct: 547 QIRERLAEFAARKAGVTPDSVRFNDDLVIAGELRVPFGELAREAYLARVQLWSDGFYTTP 606 Query: 62 KVHWDAKRMHGHPFFYFAYAAAVSEVVIDTLTGEWKLLQADLLYDAGQSLNPALDIGQVE 121 K+HWD K++ G PF+YFAY AA SEV++DTLTGEWKLL+AD L+DAG+SLNPA+DIGQVE Sbjct: 607 KLHWDQKKLQGRPFYYFAYGAACSEVLVDTLTGEWKLLRADALHDAGKSLNPAIDIGQVE 666 Query: 122 GGFIQGMGWLTTEELWWNKDGKLMTHAPSTYKIPAISDCPARLRTELFQNSNVSDTIHRS 181 G FIQGMGWLTTEELWWNKDGKLMTHAPSTYKIP I+DCP LFQN NV D+IHRS Sbjct: 667 GAFIQGMGWLTTEELWWNKDGKLMTHAPSTYKIPTINDCPEDFNVRLFQNRNVEDSIHRS 726 Query: 182 KAVGEPPLLLPFSVFLAIRDAVSAVGGHRVNPPLRAPATSEAILDAVDAVRAATAS 237 KAVGEPPLLLPFSVF AIRDA++AV ++VNPPLRAPATSEAILDAV+AVRA A+ Sbjct: 727 KAVGEPPLLLPFSVFFAIRDAIAAVADYQVNPPLRAPATSEAILDAVEAVRATCAA 782 >B3R3T3.1 B3R3T3_CUPTR XANTHINE DEHYDROGENASE (SUBUNIT B) OXIDOREDUCTASE PROTEIN EC=1.17.3.2 Length = 786 Score = 368 bits (944), Expect = e-100, Method: Compositional matrix adjust. Identities = 170/231 (73%), Positives = 193/231 (83%) Query: 2 QIRTRLAQVAAPLLGVEPTAVRFADGRVMAGAQSMAFAELVMKAYLQRVQLWSDGFYSTP 61 QIR RL AA GVEP+ VRF D V AG ++F EL +AY+ RVQLWSDGFY+TP Sbjct: 545 QIRERLTAFAARKAGVEPSEVRFNDDLVSAGELRLSFGELAREAYVARVQLWSDGFYTTP 604 Query: 62 KVHWDAKRMHGHPFFYFAYAAAVSEVVIDTLTGEWKLLQADLLYDAGQSLNPALDIGQVE 121 K+HWD K + G PF+YFAY AA SEV++DTLTGEWKLL+AD L+DAG+SLNPA+DIGQVE Sbjct: 605 KLHWDQKALQGRPFYYFAYGAACSEVLVDTLTGEWKLLRADALHDAGRSLNPAIDIGQVE 664 Query: 122 GGFIQGMGWLTTEELWWNKDGKLMTHAPSTYKIPAISDCPARLRTELFQNSNVSDTIHRS 181 G FIQGMGWLTTEELWWNKDGKLMTHAPSTYKIP ++DCP LFQN NV D+IHRS Sbjct: 665 GAFIQGMGWLTTEELWWNKDGKLMTHAPSTYKIPTVNDCPEAFNVRLFQNRNVEDSIHRS 724 Query: 182 KAVGEPPLLLPFSVFLAIRDAVSAVGGHRVNPPLRAPATSEAILDAVDAVR 232 KAVGEPPLLLPFSVF AIRDAV+A+G +R+NPPL+APATSEAILDAVDAVR Sbjct: 725 KAVGEPPLLLPFSVFFAIRDAVAALGDYRINPPLKAPATSEAILDAVDAVR 775 >E0XWN7.1 E0XWN7_9PROT Xanthine dehydrogenase, molybdopterin-binding subunit b Length = 781 Score = 358 bits (918), Expect = 5e-97, Method: Compositional matrix adjust. Identities = 171/235 (72%), Positives = 188/235 (80%) Query: 2 QIRTRLAQVAAPLLGVEPTAVRFADGRVMAGAQSMAFAELVMKAYLQRVQLWSDGFYSTP 61 QIR RLA A L G E VRF D + ++ FAELV KAYL RVQLWSDGFY+TP Sbjct: 545 QIRERLADYAVKLYGGEFACVRFFDNHIHVNGHAVPFAELVQKAYLARVQLWSDGFYATP 604 Query: 62 KVHWDAKRMHGHPFFYFAYAAAVSEVVIDTLTGEWKLLQADLLYDAGQSLNPALDIGQVE 121 + WDAK M GHPF Y+AY AAV+EVV+DTLTGEWKLL+AD LYDAGQSLNPA+D+GQVE Sbjct: 605 GLSWDAKTMTGHPFSYYAYGAAVAEVVVDTLTGEWKLLRADALYDAGQSLNPAIDLGQVE 664 Query: 122 GGFIQGMGWLTTEELWWNKDGKLMTHAPSTYKIPAISDCPARLRTELFQNSNVSDTIHRS 181 G FIQGMGWLTTE+LWWN GKLMTHAPSTYKIP ISDCP R +LFQN NV D+IHRS Sbjct: 665 GAFIQGMGWLTTEQLWWNGAGKLMTHAPSTYKIPGISDCPEDFRVKLFQNRNVEDSIHRS 724 Query: 182 KAVGEPPLLLPFSVFLAIRDAVSAVGGHRVNPPLRAPATSEAILDAVDAVRAATA 236 KAVGEPPLLLPFSVF AIRDA+S+VG H V PPL APATSE IL AV AV+AA A Sbjct: 725 KAVGEPPLLLPFSVFFAIRDAISSVGHHAVQPPLNAPATSEEILKAVMAVQAAHA 779 >F1W100.1 F1W100_9BURK Xanthine dehydrogenase, molybdenum binding subunit Length = 774 Score = 355 bits (910), Expect = 4e-96, Method: Compositional matrix adjust. Identities = 167/233 (71%), Positives = 190/233 (81%) Query: 2 QIRTRLAQVAAPLLGVEPTAVRFADGRVMAGAQSMAFAELVMKAYLQRVQLWSDGFYSTP 61 QIR RLA A V +V FADG V+ Q + FA++V KAYL RVQLWSDGFY+TP Sbjct: 539 QIRDRLAAFVAGQYDVPAASVGFADGSVLVAGQVIRFADVVAKAYLARVQLWSDGFYATP 598 Query: 62 KVHWDAKRMHGHPFFYFAYAAAVSEVVIDTLTGEWKLLQADLLYDAGQSLNPALDIGQVE 121 +HWD+ M GHPF YFAY AAVSEV+IDTLTGEWKLL+AD LYDAG+SLNPA+DIGQVE Sbjct: 599 GLHWDSASMTGHPFSYFAYGAAVSEVIIDTLTGEWKLLRADALYDAGESLNPAIDIGQVE 658 Query: 122 GGFIQGMGWLTTEELWWNKDGKLMTHAPSTYKIPAISDCPARLRTELFQNSNVSDTIHRS 181 G FIQGMGWLTTEEL WNKDGKL THAPSTYKIP +SDCP R LF+N NV+D+IHRS Sbjct: 659 GAFIQGMGWLTTEELCWNKDGKLTTHAPSTYKIPTVSDCPDDFRVALFKNRNVTDSIHRS 718 Query: 182 KAVGEPPLLLPFSVFLAIRDAVSAVGGHRVNPPLRAPATSEAILDAVDAVRAA 234 KAVGEPPLLLPFSVF AIRDAV++VG +R+NPPL APATSE IL A++AV+ A Sbjct: 719 KAVGEPPLLLPFSVFFAIRDAVASVGDYRINPPLNAPATSEEILKAIEAVQLA 771 >Q0KCW3.1 Q0KCW3_CUPNH Xanthine dehydrogenase, subunit B EC=1.17.1.4 Length = 822 Score = 351 bits (901), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 161/222 (72%), Positives = 184/222 (82%) Query: 2 QIRTRLAQVAAPLLGVEPTAVRFADGRVMAGAQSMAFAELVMKAYLQRVQLWSDGFYSTP 61 QIR RLA AA GVEP+ VRF D V AG ++F EL +AY+ RVQLWSDGFY+TP Sbjct: 545 QIRERLAVFAARKAGVEPSEVRFNDDLVSAGELRVSFGELAREAYVARVQLWSDGFYTTP 604 Query: 62 KVHWDAKRMHGHPFFYFAYAAAVSEVVIDTLTGEWKLLQADLLYDAGQSLNPALDIGQVE 121 K+HWD ++ G PF+YFAY AA SEV++DTLTGEWKLL+AD L+DAG+SLNPA+DIGQVE Sbjct: 605 KLHWDQSKLQGRPFYYFAYGAACSEVLVDTLTGEWKLLRADALHDAGRSLNPAIDIGQVE 664 Query: 122 GGFIQGMGWLTTEELWWNKDGKLMTHAPSTYKIPAISDCPARLRTELFQNSNVSDTIHRS 181 G FIQGMGWLTTEELWWNKDGKLMTHAPSTYKIP ++DCP LFQN NV D+IHRS Sbjct: 665 GAFIQGMGWLTTEELWWNKDGKLMTHAPSTYKIPTVNDCPEEFNVRLFQNRNVEDSIHRS 724 Query: 182 KAVGEPPLLLPFSVFLAIRDAVSAVGGHRVNPPLRAPATSEA 223 KAVGEPPLLLPFSVF AIRDAV+AVG +R+NPPL+APATSE Sbjct: 725 KAVGEPPLLLPFSVFFAIRDAVAAVGDYRINPPLKAPATSEG 766 >D5NI79.1 D5NI79_9BURK Xanthine dehydrogenase, molybdopterin binding subunit EC=1.17.1.4 Length = 801 Score = 351 bits (900), Expect = 5e-95, Method: Compositional matrix adjust. Identities = 169/237 (71%), Positives = 196/237 (82%), Gaps = 1/237 (0%) Query: 3 IRTRLAQVAAPLLGVEPTAVRFADGRVMAGAQSMAFAELVMKAYLQRVQLWSDGFYSTPK 62 IR RLA +AA LG T V+FA+G+V +M F +LV AYL RVQLWSDGFY+TPK Sbjct: 553 IRERLAGLAAKQLGGSATDVQFANGQVSVNGGAMPFEQLVSAAYLARVQLWSDGFYTTPK 612 Query: 63 VHWDAKRMHGHPFFYFAYAAAVSEVVIDTLTGEWKLLQADLLYDAGQSLNPALDIGQVEG 122 VHWDAK + GHPF+YFAY AAVSEVVIDTLTGEWKL++AD+L+DAGQS+NPA+DIGQVEG Sbjct: 613 VHWDAKTLTGHPFYYFAYGAAVSEVVIDTLTGEWKLVRADVLHDAGQSINPAIDIGQVEG 672 Query: 123 GFIQGMGWLTTEELWWNKDGKLMTHAPSTYKIPAISDCPARLRTELFQNSNVSDTIHRSK 182 GFIQGMGWLTTEELWWN+DG+LMTHAPSTYKIPA+SD PA L+QN N T+ RSK Sbjct: 673 GFIQGMGWLTTEELWWNRDGRLMTHAPSTYKIPAVSDTPAAFHVRLYQNHNAEPTVFRSK 732 Query: 183 AVGEPPLLLPFSVFLAIRDAV-SAVGGHRVNPPLRAPATSEAILDAVDAVRAATASR 238 AVGEPPLLLPFSVFLAIRDA+ +AV G R PPLRAPAT EAILDA+DA+++ A + Sbjct: 733 AVGEPPLLLPFSVFLAIRDAIAAAVPGAREAPPLRAPATPEAILDALDALQSQPARQ 789 >Q1LPZ8.1 Q1LPZ8_RALME Xanthine dehydrogenase, subunit B EC=1.17.1.4 Length = 783 Score = 348 bits (894), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 161/225 (71%), Positives = 185/225 (82%) Query: 2 QIRTRLAQVAAPLLGVEPTAVRFADGRVMAGAQSMAFAELVMKAYLQRVQLWSDGFYSTP 61 QIR RLA AA GV VRF D V+AG +F +L +AY+ RVQLWSDGFY+TP Sbjct: 547 QIRERLAAFAARKAGVPVEDVRFGDDLVVAGELRQSFGDLAREAYVARVQLWSDGFYTTP 606 Query: 62 KVHWDAKRMHGHPFFYFAYAAAVSEVVIDTLTGEWKLLQADLLYDAGQSLNPALDIGQVE 121 K+HWD K + G PF+Y+AY AA SEV++DTLTGEWKLL+AD L+DAG+SLNPA+DIGQVE Sbjct: 607 KLHWDQKALQGRPFYYYAYGAACSEVLVDTLTGEWKLLRADALHDAGKSLNPAIDIGQVE 666 Query: 122 GGFIQGMGWLTTEELWWNKDGKLMTHAPSTYKIPAISDCPARLRTELFQNSNVSDTIHRS 181 G FIQGMGWLTTEELWWN++GKLMTHAPSTYKIP I+DCP LFQN NV D+IHRS Sbjct: 667 GAFIQGMGWLTTEELWWNQNGKLMTHAPSTYKIPTINDCPEEFNVRLFQNRNVEDSIHRS 726 Query: 182 KAVGEPPLLLPFSVFLAIRDAVSAVGGHRVNPPLRAPATSEAILD 226 KAVGEPPLLLPFSVF AIRDA++AVG ++VNPPLRAPATSEAILD Sbjct: 727 KAVGEPPLLLPFSVFFAIRDAIAAVGDYKVNPPLRAPATSEAILD 771 >D8D0T9.1 D8D0T9_COMTE Xanthine dehydrogenase, molybdopterin binding subunit Length = 808 Score = 348 bits (894), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 167/236 (70%), Positives = 190/236 (80%), Gaps = 1/236 (0%) Query: 2 QIRTRLAQVAAPLLGVEPTAVRFADGRVMAGAQSMAFAELVMKAYLQRVQLWSDGFYSTP 61 Q+R RLA+ AA L G + VRFA+ V Q++ FAELV AYLQRVQLWSDGFY+TP Sbjct: 573 QLRERLAECAARLHGGDAHDVRFANNAVQVNGQNVPFAELVRAAYLQRVQLWSDGFYATP 632 Query: 62 KVHWDAKRMHGHPFFYFAYAAAVSEVVIDTLTGEWKLLQADLLYDAGQSLNPALDIGQVE 121 +HWD KRM GHPFFYFAY AAVSEVVIDTLTGEWKLL+AD+L+D G+SLNPA+D+GQVE Sbjct: 633 GLHWDGKRMKGHPFFYFAYGAAVSEVVIDTLTGEWKLLRADVLHDVGRSLNPAVDVGQVE 692 Query: 122 GGFIQGMGWLTTEELWWN-KDGKLMTHAPSTYKIPAISDCPARLRTELFQNSNVSDTIHR 180 G FIQGMGWLTTEEL W+ + GKL THAPSTYKIP +DCP LF+ N D+IHR Sbjct: 693 GAFIQGMGWLTTEELVWHPQTGKLTTHAPSTYKIPTANDCPPVFNVRLFEGDNYEDSIHR 752 Query: 181 SKAVGEPPLLLPFSVFLAIRDAVSAVGGHRVNPPLRAPATSEAILDAVDAVRAATA 236 SKAVGEPPLLLPFSVF AIRDAVSA G HR+NPPL+APATSEAIL AV+AV+ T Sbjct: 753 SKAVGEPPLLLPFSVFFAIRDAVSAAGEHRMNPPLQAPATSEAILRAVEAVQGHTG 808