BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0080.p (289 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J1X9.1 D8J1X9_HERSS PHP family metal-dependent phosphoesterase... 478 e-133 A4G730.1 A4G730_HERAR Putative metal-dependent phosphoesterases ... 348 6e-94 Q1LPH6.1 Q1LPH6_RALME Putative metal-dependent phosphoesterase (... 330 1e-88 F1VXC3.1 F1VXC3_9BURK Putative metal-dependent phosphoesterases ... 330 1e-88 Q0KCD0.1 Q0KCD0_CUPNH Predicted metal-dependent phosphoesterase ... 321 1e-85 Q473F5.1 Q473F5_CUPPJ PHP, C-terminal 318 5e-85 A2W933.1 A2W933_9BURK Phosphoesterase PHP 313 2e-83 A6SXH0.1 A6SXH0_JANMA Uncharacterized conserved protein 313 2e-83 D8ND49.1 D8ND49_RALSO Putative uncharacterized protein 311 7e-83 E1T427.1 E1T427_BURSG PHP domain protein 310 2e-82 >D8J1X9.1 D8J1X9_HERSS PHP family metal-dependent phosphoesterase protein Length = 282 Score = 478 bits (1230), Expect = e-133, Method: Compositional matrix adjust. Identities = 231/234 (98%), Positives = 232/234 (99%) Query: 56 VXRVRAAAQALGMVHVGGVEISVTWAGHTVHIVGLQIDETNPALVQGLAATRNGRERRAR 115 V R RAAAQALGMVHVGGVEISVTWAGHTVHIVGLQIDETNPALVQGLAATRNGRERRAR Sbjct: 49 VARARAAAQALGMVHVGGVEISVTWAGHTVHIVGLQIDETNPALVQGLAATRNGRERRAR 108 Query: 116 EIAAQLEQHGVAGAYEGALKHVGNPDLISRTHFARFMVECGRCCDTREVFANYLTEGKPG 175 EIAAQLEQHGVAGAYEGALKHVGNPDLISRTHFARFMVECGRCCDTREVFANYLTEGKPG Sbjct: 109 EIAAQLEQHGVAGAYEGALKHVGNPDLISRTHFARFMVECGRCCDTREVFANYLTEGKPG 168 Query: 176 YVPHRWATLEEAVRWIRGAGGVAVIAHPGRYKYSETQFGAFFDEFRQLGGAAIEVNTGSH 235 YVPHRWATLEEAVRWIRGAGGVAVIAHPGRYKYSETQFGAFFDEFRQLGGAAIEVNTGSH Sbjct: 169 YVPHRWATLEEAVRWIRGAGGVAVIAHPGRYKYSETQFGAFFDEFRQLGGAAIEVNTGSH 228 Query: 236 TPEQYQQYAQVARYYGFLASMGSDFHGPGESRVDLGGLPPLPQGVKPVWHDWAL 289 TPEQYQQYAQVAR+YGFLASMGSDFHGPGESRVDLGGLPPLPQGVKPVWHDWAL Sbjct: 229 TPEQYQQYAQVARHYGFLASMGSDFHGPGESRVDLGGLPPLPQGVKPVWHDWAL 282 >A4G730.1 A4G730_HERAR Putative metal-dependent phosphoesterases (PHP family) Length = 276 Score = 348 bits (892), Expect = 6e-94, Method: Compositional matrix adjust. Identities = 165/235 (70%), Positives = 187/235 (79%) Query: 53 VVRVXRVRAAAQALGMVHVGGVEISVTWAGHTVHIVGLQIDETNPALVQGLAATRNGRER 112 V + R AA AL + V GVEIS+TWA TVHIVGLQIDE N ALVQGLAATR GRE+ Sbjct: 42 VSGIAEARVAATALDLPFVSGVEISITWAAQTVHIVGLQIDEKNAALVQGLAATRGGREQ 101 Query: 113 RAREIAAQLEQHGVAGAYEGALKHVGNPDLISRTHFARFMVECGRCCDTREVFANYLTEG 172 RAREI+AQL G+ A+EGALK VGNPDLISRTHFAR+++E G D +VFA+YL EG Sbjct: 102 RAREISAQLAAAGIPDAFEGALKFVGNPDLISRTHFARYIIELGLSKDLHDVFADYLGEG 161 Query: 173 KPGYVPHRWATLEEAVRWIRGAGGVAVIAHPGRYKYSETQFGAFFDEFRQLGGAAIEVNT 232 KPG+VPHRWATL+ AV WIRGAGG+AVIAHPGRYK+S+ F A F EF+ LGGA IEV T Sbjct: 162 KPGFVPHRWATLQNAVEWIRGAGGIAVIAHPGRYKFSDLAFDALFQEFKDLGGAGIEVTT 221 Query: 233 GSHTPEQYQQYAQVARYYGFLASMGSDFHGPGESRVDLGGLPPLPQGVKPVWHDW 287 GSHT +QY YA+VA+ Y FLAS GSDFHGPGESR+DLG LPPLP GV PVWHDW Sbjct: 222 GSHTADQYDYYAKVAKNYSFLASRGSDFHGPGESRIDLGKLPPLPHGVTPVWHDW 276 >Q1LPH6.1 Q1LPH6_RALME Putative metal-dependent phosphoesterase (PHP family) EC=3.1.-.- Length = 322 Score = 330 bits (847), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 156/228 (68%), Positives = 188/228 (82%) Query: 60 RAAAQALGMVHVGGVEISVTWAGHTVHIVGLQIDETNPALVQGLAATRNGRERRAREIAA 119 R AA+ALGM +V GVEISVTWAG TVHIVGLQID +P L+ GLA TR+GR RRA++I Sbjct: 95 RRAAEALGMRYVPGVEISVTWAGQTVHIVGLQIDPFHPELIDGLAKTRDGRARRAQDIGD 154 Query: 120 QLEQHGVAGAYEGALKHVGNPDLISRTHFARFMVECGRCCDTREVFANYLTEGKPGYVPH 179 L + G++GAY+GAL++VGNPDLISRTHFAR++V+ GRC +VFA YL+EG+PG+VPH Sbjct: 155 ALAKVGISGAYDGALRYVGNPDLISRTHFARWLVDEGRCATIGDVFAEYLSEGRPGFVPH 214 Query: 180 RWATLEEAVRWIRGAGGVAVIAHPGRYKYSETQFGAFFDEFRQLGGAAIEVNTGSHTPEQ 239 RWATL EAV WIR AGG+ V+AHPGRY Y++TQ A FDEF QLGG A+EV TGSHTP+Q Sbjct: 215 RWATLAEAVGWIRTAGGIPVMAHPGRYNYTDTQHDALFDEFTQLGGRAVEVVTGSHTPDQ 274 Query: 240 YQQYAQVARYYGFLASMGSDFHGPGESRVDLGGLPPLPQGVKPVWHDW 287 +++YA VAR+YG LAS GSDFHGPGE RV+LG LPPLP V PVW+DW Sbjct: 275 FRRYANVARHYGLLASRGSDFHGPGEGRVELGALPPLPADVTPVWYDW 322 >F1VXC3.1 F1VXC3_9BURK Putative metal-dependent phosphoesterases (PHP family) Length = 282 Score = 330 bits (847), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 156/234 (66%), Positives = 182/234 (77%) Query: 56 VXRVRAAAQALGMVHVGGVEISVTWAGHTVHIVGLQIDETNPALVQGLAATRNGRERRAR 115 + R AAQAL + + GVEIS+TWAG TVHIVGLQIDETNP LV GL +TR+GRE+RA Sbjct: 45 IAEARHAAQALDLQFIAGVEISITWAGETVHIVGLQIDETNPQLVLGLDSTRSGREQRAH 104 Query: 116 EIAAQLEQHGVAGAYEGALKHVGNPDLISRTHFARFMVECGRCCDTREVFANYLTEGKPG 175 E+A QL G+ A+EGAL VGNPDLISRTHFAR+++E G C D +VF+ YL EG+PG Sbjct: 105 EMADQLAMVGIPDAFEGALNFVGNPDLISRTHFARYLIEIGECRDVPDVFSKYLIEGRPG 164 Query: 176 YVPHRWATLEEAVRWIRGAGGVAVIAHPGRYKYSETQFGAFFDEFRQLGGAAIEVNTGSH 235 YVPHRWATL++AV WIRGAGG AV+AHPGRY +S+ Q GAF DEF GG+AIEV TGSH Sbjct: 165 YVPHRWATLQQAVEWIRGAGGTAVVAHPGRYDFSDLQLGAFLDEFISYGGSAIEVMTGSH 224 Query: 236 TPEQYQQYAQVARYYGFLASMGSDFHGPGESRVDLGGLPPLPQGVKPVWHDWAL 289 T +QY +A++A YG AS GSDFHGPGESRVDLG LPPLP V PVW DW L Sbjct: 225 TVDQYDTFARMATRYGLRASRGSDFHGPGESRVDLGALPPLPPSVTPVWADWDL 278 >Q0KCD0.1 Q0KCD0_CUPNH Predicted metal-dependent phosphoesterase (PHP family) EC=3.1.-.- Length = 281 Score = 321 bits (822), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 153/222 (68%), Positives = 178/222 (80%) Query: 66 LGMVHVGGVEISVTWAGHTVHIVGLQIDETNPALVQGLAATRNGRERRAREIAAQLEQHG 125 GM +V GVEISVTWAG TVHIVGLQID P L+ GL TR+GR RRAR+IA L + G Sbjct: 60 FGMRYVPGVEISVTWAGQTVHIVGLQIDPHCPELIDGLTDTRSGRARRARDIAEALAKVG 119 Query: 126 VAGAYEGALKHVGNPDLISRTHFARFMVECGRCCDTREVFANYLTEGKPGYVPHRWATLE 185 + GAYEGAL+HVGNPDLISRTHFAR++V+ GRC EVF+ YL+EG+PGYV HRWA+L Sbjct: 120 ITGAYEGALQHVGNPDLISRTHFARWLVDQGRCATVGEVFSEYLSEGRPGYVGHRWASLA 179 Query: 186 EAVRWIRGAGGVAVIAHPGRYKYSETQFGAFFDEFRQLGGAAIEVNTGSHTPEQYQQYAQ 245 +AV WIR AGG+AV+AHPGRY Y++TQ A FDEF LGG A+EV TGSHTP+QY++YA Sbjct: 180 DAVGWIRAAGGIAVMAHPGRYNYTDTQHDALFDEFTALGGGAVEVVTGSHTPDQYRRYAA 239 Query: 246 VARYYGFLASMGSDFHGPGESRVDLGGLPPLPQGVKPVWHDW 287 VAR+YG LAS GSDFHGPGE RV+LG LPPLP V PVW DW Sbjct: 240 VARHYGLLASRGSDFHGPGEGRVELGKLPPLPSTVTPVWRDW 281 >Q473F5.1 Q473F5_CUPPJ PHP, C-terminal Length = 281 Score = 318 bits (815), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 151/222 (68%), Positives = 177/222 (79%) Query: 66 LGMVHVGGVEISVTWAGHTVHIVGLQIDETNPALVQGLAATRNGRERRAREIAAQLEQHG 125 LGM +V GVEISVTWAG TVHIVGLQID P L+ GLA TR+GR RRAR+I L + G Sbjct: 60 LGMRYVCGVEISVTWAGQTVHIVGLQIDPFAPELIDGLADTRSGRARRARDIGEALGKIG 119 Query: 126 VAGAYEGALKHVGNPDLISRTHFARFMVECGRCCDTREVFANYLTEGKPGYVPHRWATLE 185 + AY+GALK+VGNPDLISRTHFAR++V+ G C +VF+ YL+EG+PGYV HRWA L Sbjct: 120 IENAYQGALKYVGNPDLISRTHFARWLVDQGHCATIGDVFSQYLSEGRPGYVGHRWANLS 179 Query: 186 EAVRWIRGAGGVAVIAHPGRYKYSETQFGAFFDEFRQLGGAAIEVNTGSHTPEQYQQYAQ 245 +A+ WIR AGG+AV+AHPGRY Y++TQ A FDEF LGG A+EV TGSHTP+QY++YA Sbjct: 180 DAIGWIRAAGGIAVMAHPGRYNYTDTQHDALFDEFTALGGRAVEVVTGSHTPDQYRRYAD 239 Query: 246 VARYYGFLASMGSDFHGPGESRVDLGGLPPLPQGVKPVWHDW 287 VARYYG LAS GSDFHGPGE RV+LG LPPLP V PVWHDW Sbjct: 240 VARYYGLLASRGSDFHGPGEGRVELGALPPLPSTVTPVWHDW 281 >A2W933.1 A2W933_9BURK Phosphoesterase PHP Length = 279 Score = 313 bits (801), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 153/228 (67%), Positives = 176/228 (77%) Query: 60 RAAAQALGMVHVGGVEISVTWAGHTVHIVGLQIDETNPALVQGLAATRNGRERRAREIAA 119 R+ A+ALGM ++ GVEISVTWA TVHIVGL +D NPALV GL TR+GR RA+ I A Sbjct: 51 RSEAEALGMRYLCGVEISVTWASRTVHIVGLNVDPANPALVDGLHRTRHGRAARAQAIGA 110 Query: 120 QLEQHGVAGAYEGALKHVGNPDLISRTHFARFMVECGRCCDTREVFANYLTEGKPGYVPH 179 QL G+ GAYEGALK V NPDLISRTHFARF+VE G T +VF L +GKPG+VPH Sbjct: 111 QLATLGIPGAYEGALKFVSNPDLISRTHFARFLVENGHAESTADVFDRLLGDGKPGFVPH 170 Query: 180 RWATLEEAVRWIRGAGGVAVIAHPGRYKYSETQFGAFFDEFRQLGGAAIEVNTGSHTPEQ 239 RWATL +AVRWIRGAGG AV+AHPGRY+Y+ +F AFF EF LGG AIEV TGSHTP+Q Sbjct: 171 RWATLSDAVRWIRGAGGEAVVAHPGRYRYTPVEFDAFFGEFIDLGGRAIEVVTGSHTPDQ 230 Query: 240 YQQYAQVARYYGFLASMGSDFHGPGESRVDLGGLPPLPQGVKPVWHDW 287 Y++YA VAR +GF AS GSDFH PGE RV+LG LPPLP +KPVW W Sbjct: 231 YREYADVARRFGFEASRGSDFHAPGEGRVELGSLPPLPSDLKPVWERW 278 >A6SXH0.1 A6SXH0_JANMA Uncharacterized conserved protein Length = 278 Score = 313 bits (801), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 158/222 (71%), Positives = 181/222 (81%) Query: 66 LGMVHVGGVEISVTWAGHTVHIVGLQIDETNPALVQGLAATRNGRERRAREIAAQLEQHG 125 L + V GVEIS+TW+G TVHIVGLQIDETN LV GLA TR GRE RAREIAAQLE+ G Sbjct: 55 LDLPFVAGVEISITWSGQTVHIVGLQIDETNETLVNGLATTRGGREPRAREIAAQLEKIG 114 Query: 126 VAGAYEGALKHVGNPDLISRTHFARFMVECGRCCDTREVFANYLTEGKPGYVPHRWATLE 185 + GAYEGALK V NPDLISRTHFAR+++E G C + +VFANYL EGKPG+VPHRWA+L+ Sbjct: 115 IKGAYEGALKFVDNPDLISRTHFARYIIELGLCDNLHDVFANYLGEGKPGFVPHRWASLQ 174 Query: 186 EAVRWIRGAGGVAVIAHPGRYKYSETQFGAFFDEFRQLGGAAIEVNTGSHTPEQYQQYAQ 245 +V WIR AGG+AVIAHPGRYK+++ F A F EF+ GG IEV TGSHT +QY YA+ Sbjct: 175 NSVEWIRAAGGIAVIAHPGRYKFTDLAFDALFKEFKSFGGVGIEVTTGSHTVDQYDFYAK 234 Query: 246 VARYYGFLASMGSDFHGPGESRVDLGGLPPLPQGVKPVWHDW 287 VA+ Y FLAS GSDFHGPGESRVDLGGLPPLP GVKPVWH+W Sbjct: 235 VAKDYDFLASRGSDFHGPGESRVDLGGLPPLPLGVKPVWHNW 276 >D8ND49.1 D8ND49_RALSO Putative uncharacterized protein Length = 286 Score = 311 bits (797), Expect = 7e-83, Method: Compositional matrix adjust. Identities = 151/228 (66%), Positives = 176/228 (77%) Query: 60 RAAAQALGMVHVGGVEISVTWAGHTVHIVGLQIDETNPALVQGLAATRNGRERRAREIAA 119 R AA++LGM ++ GVEISVTWAG T+HIVGL ID + ALVQGLA TR+GR RA ++A Sbjct: 57 REAAESLGMDYLAGVEISVTWAGRTLHIVGLGIDPDDAALVQGLARTRSGRCARAEDMAE 116 Query: 120 QLEQHGVAGAYEGALKHVGNPDLISRTHFARFMVECGRCCDTREVFANYLTEGKPGYVPH 179 L + G+ GAYEGAL + GNPD+ISRTHFARF+VE G C D EVFA YL EGKPG+VPH Sbjct: 117 ALGKLGIHGAYEGALSYAGNPDMISRTHFARFLVEHGHCRDIAEVFARYLGEGKPGFVPH 176 Query: 180 RWATLEEAVRWIRGAGGVAVIAHPGRYKYSETQFGAFFDEFRQLGGAAIEVNTGSHTPEQ 239 RW+ L +A+ WIRGAGGVAV+AHPGRY + + GA FDEF+ LGG +EV TGSHTP+Q Sbjct: 177 RWSRLADAIGWIRGAGGVAVMAHPGRYTLTLLEHGALFDEFKDLGGEGVEVVTGSHTPDQ 236 Query: 240 YQQYAQVARYYGFLASMGSDFHGPGESRVDLGGLPPLPQGVKPVWHDW 287 Y YA VAR YG LAS GSDFHGPGE RVDLG LPPLP + PVW W Sbjct: 237 YACYADVARRYGLLASRGSDFHGPGEGRVDLGELPPLPDNLTPVWSRW 284 >E1T427.1 E1T427_BURSG PHP domain protein Length = 277 Score = 310 bits (794), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 150/228 (65%), Positives = 174/228 (76%) Query: 60 RAAAQALGMVHVGGVEISVTWAGHTVHIVGLQIDETNPALVQGLAATRNGRERRAREIAA 119 R AA+ALGM ++ GVE SVTWA TVHIVGL ID T+ L+ GLA TRNGR RA I Sbjct: 49 RQAAEALGMGYLSGVETSVTWAARTVHIVGLGIDPTSSVLIDGLARTRNGRAARAEAIGE 108 Query: 120 QLEQHGVAGAYEGALKHVGNPDLISRTHFARFMVECGRCCDTREVFANYLTEGKPGYVPH 179 QL G+ GAYEGALK+V NPD+ISRTHFARF+VE G T++VF YL +GKPGYVPH Sbjct: 109 QLATLGIPGAYEGALKYVSNPDMISRTHFARFLVESGHASSTQDVFNRYLGDGKPGYVPH 168 Query: 180 RWATLEEAVRWIRGAGGVAVIAHPGRYKYSETQFGAFFDEFRQLGGAAIEVNTGSHTPEQ 239 RW+ L +AV WI+ AGG A+IAHPGRY YS T+F AFF EF LGG AIEV TGSHTP+Q Sbjct: 169 RWSKLADAVGWIKAAGGEAIIAHPGRYAYSPTEFDAFFAEFIDLGGKAIEVVTGSHTPDQ 228 Query: 240 YQQYAQVARYYGFLASMGSDFHGPGESRVDLGGLPPLPQGVKPVWHDW 287 Y++YA+VAR +GF AS GSDFH PGE RV+LG LPPLP +KPVW W Sbjct: 229 YREYAEVARRFGFEASRGSDFHAPGEGRVELGTLPPLPSDLKPVWERW 276